CN209270613U - A kind of premature LISA/MIST delivery catheter - Google Patents

Abstract

The utility model discloses a kind of premature LISA/MIST delivery catheters, the antireflux device including catheter main body and conduit head end.Antireflux device is made of elastic emulsion film, expansible in the form of annular discs or spherical at positive pressure, can retract original state when removing positive pressure by natural resiliency bullet, Emulsoid-film top have a rubber ring collar at duct diffuse into as PS the access of tracheae.By the push syringe PS administration of LISA/MIST operating method, the Emulsoid-film of conduit head end will extend and expand under the action of positive pressure, through main bronchus inner wall, continue to positive pressure, PS will be enclosed by the rubber hole on Emulsoid-film top by injection infant main bronchus, main bronchus chamber is blocked up close at this time by the conduit head end expanded due to by positive pressure, to effectively reduce the PS for having been injected into main bronchus by the gap leakage reflux between tubule and main bronchus, the clinical application effect of premature LISA/MIST technology is improved.

Description

A kind of premature LISA/MIST delivery catheter

Technical field

The utility model relates to a kind of premature's clinic giving using LISA/MIST technology injection alveolar surfactant Medicine conduit device.

Background technique

Respiratory Distress Syndrome(RDS) is common one of the clinical disease of premature." European Respiratory Distress Syndrome(RDS) pipe in 2016 Manage guide " by premature's early stage continuous positive airway, combine pulmonary surfactant (pulmonary surfactant, PS) replacement therapy is considered as " the gold combination " of hyaline membrane disease of prematurity treatment.It is referred in guide using minimal invasive techniques Two kinds of main stream approach of PS are injected i.e. by tubule: LISA method (less invasive surfactant Administration) and MIST method (minimally invasive surfactant treatment), hereinafter referred to as (LISA/MIST)。

From traditional transtracheal intubation passage that PS injection is different, LISA/MIST technology is replaced using the thinner conduit of diameter Trachea cannula injects PS, it is a technical advantage that: (1) it looks at straight under laryngoscope and is placed in tubule, operate simpler.(2) tubule is placed in Trachea cannula is substituted, the damage to vocal cords and tracheal mucosa is reduced.(3) PS is not necessarily to pressure-vent with process, and PS is avoided to use Elevated pressures or excessive atelectasis lead to Premature lung injury in the process.Therefore, LISA/MIST technology can be considered that Premature Lung is protected A part of shield property strategy.

LISA/MIST technology on the one hand conventional trachea cannula replaced using tubule can reduce the stimulation to air flue mucous membrane and On the other hand damage is then increased the gap between tubule and infant main bronchus, therefore is either made using 4~5FG stomach tube For the LISA technology of PS administration route, or the MIST skill of approach is injected using 16G cannula of deep vein casing substitution stomach tube as PS Art is all suffered from PS injection process and is largely leaked outside and this problem of reflux.On the one hand leakage causes to be efficiently entering trouble with reflux The PS of youngster's lung tissue is seriously reduced, and is fallen flat, and is generally required supplement PS dosage to make up loss, is increased and suffer from Fang Jing Ji burden；On the other hand the operating time of injection is extended, cough of choking, apnea, pulse oxygen occurs in infant during increasing Saturation degree and the risk and pollution probability of heart rate decline.Therefore, the leakage of PS and reflux problem become influence in injection process One of the key factor of LISA/MIST technology curative effect.There is presently no a kind of dedicated PS for premature's LISA/MIST technology Drug delivery device.

Utility model content

For above-mentioned deficiency in the prior art, the utility model provides a kind of for premature LISA/MIST technology PS delivery catheter, the conduit head end have antireflux device design, can reduce because PS drug extravasation reflux fails to be efficiently entering trouble Influence of youngster's lung tissue to curative effect improves the clinical application effect of premature LISA/MIST technology.

In order to achieve the above object of the invention, the technical solution that the utility model premature LISA/MIST delivery catheter uses Are as follows: the antireflux device including LISA/MIST delivery catheter main body and conduit head end.Delivery catheter main body overall length 15cm, outer diameter 2mm, internal diameter 1.5mm, is made of polyvinyl chloride macromolecule material, and flexibility is good.Catheter main body side wall is provided with graduation mark, from Start away from conduit head end 5cm, until terminating away from conduit head end 12cm, one graduation mark is set every 1cm.Head end antireflux device overall length 0.5cm, by can the Emulsoid-film of automatic retracted be made, elasticity is good, and deformation ductility is good, and expansible at positive pressure is in disk Shape is spherical, can retract original state when removing positive pressure by natural resiliency bullet, and Emulsoid-film top is the rubber ring of a diameter 1.0mm Ring diffuses into the access of tracheae as PS.

Compared with the prior art, the advantages of the utility model are: by LISA/MIST technology operation method in direct-view laryngoscope It is lower that delivery catheter is passed through into glottis merging infant main bronchus, delivery catheter tail end is connected by syringe and injects PS, works as push When syringe is to PS, the Emulsoid-film of conduit head end will extend and expand under the action of liquid/gas positive pressure, and go directly main bronchus Inner wall continues to push syringe application positive pressure, and PS will be enclosed by the rubber hole on Emulsoid-film top by injection infant main bronchus, Because at this time by positive pressure due to the conduit head end that expands has been closed main bronchus chamber is completely stifled, avoid and have been injected into main bronchus PS is by the excessive reflux gas off-take in gap between tubule and main bronchus, to efficiently reduce the implementation of LISA/MIST technology In the process because leakage reflux caused by PS loss and potential pollution risk, improve the clinical application effect of LISA/MIST.

Detailed description of the invention

Fig. 1 is the side structure schematic diagram of the utility model PS intrarterial conduit

Fig. 2 is the cross-sectional structure schematic diagram of the utility model PS intrarterial conduit head end (when positive-pressure administration expands)

Fig. 3 is the utility model PS intrarterial conduit embodiments figure.

Wherein, 1, LISA/MIST delivery catheter main body；2, catheter main body side wall graduation mark；3, tail end of conduit interface；4, it leads Tube head end Emulsoid-film；5, the rubber ring of Emulsoid-film center；6, rubber ring collar at PS drug dispersion duct；7, infant Inner surface of trachea；8,5mL sterilizing syringe.

Specific embodiment

Specific embodiment of the present utility model is described below, in order to facilitate understanding by those skilled in the art The utility model, it should be apparent that the utility model is not limited to the range of specific embodiment, to the common skill of the art For art personnel, if various change the attached claims limit and determine the utility model spirit and scope in, These variations are it will be apparent that all utilize the innovation and creation of the utility model design in the column of protection.

Fig. 1 shows the side structure schematic diagram of PS intrarterial conduit, and Fig. 2 shows the transversal of delivery catheter head end Face structural schematic diagram.With reference to Fig. 1 and Fig. 2, the technical solution of premature's LISA/MIST delivery catheter of the present embodiment are as follows:

Antireflux Emulsoid-film 4 including LISA/MIST delivery catheter main body 1 and conduit head end, Emulsoid-film 4 by It may expand expansion when gas or liquid positive pressure, form cross section antireflux Emulsoid-film 4 as shown in Figure 2, Emulsoid-film 4 Center is PS via hole 6 when being administered, and has a circle rubber ring 5 around via hole 6, to protect 6 quilt of via hole in 4 expansion process of Emulsoid-film Excessively drawing tearing.

With reference to Fig. 3, operator estimates that conduit is inserted into tracheae depth according to premature infant weight in advance, operates by LISA/MIST Regulation is inserted into delivery catheter main body 1 in the case where looking at laryngoscope straight, stops insertion and properly fixed catheter main body 1 in suitable depth, will Tail end of conduit interface 3 connects the syringe 8 for having aspirated PS in advance, injects PS according to LISA/MIST dose regimen push syringe Catheter main body 1 continues to push syringe 8 at PS injection conduit head end Emulsoid-film 4, leads under gas or liquid positive pressure The Emulsoid-film 4 of pipe front end is opened in intratracheal expansion, and the gap between catheter main body 1 and inner surface of trachea 7 is filled up, is enclosed The space that disperse hole 6 enters the outside reflux of PS of main bronchus is hit exactly by film, PS can only continue forward disperse and enter lung group It knits.When injecting period (such as 5 seconds) terminates to stop push syringe 8, the natural resiliency that acts on that Emulsoid-film 4 loses positive pressure is returned Restore under the action of contracting power to unexpanded original state shown in Fig. 1, can go out again again between catheter main body 1 and inner surface of trachea 7 Existing gap, extraneous oxygen can be inhaled into lung tissue for used in body by this gap under the autonomous respiration of infant at this time.Between After 10 seconds, operator can be again started up injection Periodic Traveling PS administration next time, and the expansion that then reexpands of Emulsoid-film 4 is filled up and led The leakage reflux of PS when gap between pipe main body 1 and inner surface of trachea 7 is to prevent injection.

In conclusion the utility model PS delivery catheter using head end Emulsoid-film elastic stretching expansion fill up conduit with Gap between inner surface of trachea, can effectively reduce premature LISA/MIST operation when PS leakage and reflux, reduce PS loss and Potential pollution risk improves the clinical application effect of LISA/MIST technology.A whole set of system uses safe and non-toxic common material Material, structure is simple, economical and practical.

Claims (6)

1. a kind of premature LISA/MIST delivery catheter, it is characterised in that: including LISA/MIST delivery catheter main body and conduit The antireflux device of head end.

2. premature LISA/MIST delivery catheter according to claim 1, it is characterised in that: the delivery catheter main body It is made of polyvinyl chloride macromolecule material, flexibility is good.

3. premature LISA/MIST delivery catheter according to claim 2, it is characterised in that: the catheter main body side wall It is provided with graduation mark.

4. premature LISA/MIST delivery catheter according to claim 1, it is characterised in that: the conduit head end is prevented Reflux device by can the Emulsoid-film of automatic retracted be made, elasticity is good, and deformation ductility is good, expansible in circle at positive pressure Plate-like is spherical, can retract original state by natural resiliency bullet when removing positive pressure.

5. premature LISA/MIST delivery catheter according to claim 4, it is characterised in that: the Emulsoid-film top There is a duct to enter the access of tracheae as drug diffusion.

6. premature LISA/MIST delivery catheter according to claim 5, it is characterised in that: the duct periphery is one Rubber ring is enclosed, to protect duct not to be torn when being pulled expansion.