CN209270606U - Orthopaedics implantable drug delivery system - Google Patents

Orthopaedics implantable drug delivery system Download PDF

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Publication number
CN209270606U
CN209270606U CN201820198285.8U CN201820198285U CN209270606U CN 209270606 U CN209270606 U CN 209270606U CN 201820198285 U CN201820198285 U CN 201820198285U CN 209270606 U CN209270606 U CN 209270606U
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China
Prior art keywords
administration
needle
sleeve
drug delivery
delivery system
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CN201820198285.8U
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Chinese (zh)
Inventor
崔壮
吴航天
余斌
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Southern Hospital Southern Medical University
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Southern Hospital Southern Medical University
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Priority to CN201820198285.8U priority Critical patent/CN209270606U/en
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Abstract

The utility model discloses orthopaedics implantable drug delivery systems, and including administration sleeve and the administration needle being inserted into administering cover, administration needle connects administration pump by perfusion tube, and administration needle includes the fixing head of needle tubing and fixed needle tubing, and fixing head and the inner wall of administration sleeve are fixed.The utility model designs administration needle insertion administration sleeve, administration sleeve is implanted into subchondral bone, feeding drug by administration pump through the lasting slow constant speed of administration needle, achievable subchondral bone is administered at regular time and quantity, simultaneously when traditional subchondral bone being avoided disposably to inject or be embedded to drug drug release can not quantify and unstability, the utility model can be widely applied to medical instruments field.

Description

Orthopaedics implantable drug delivery system
Technical field
The utility model relates to the field of medical instrument technology, in particular to orthopaedics implantable drug delivery system.
Background technique
Clinical practice shows that subchondral bone lesion is the key factor that osteoarthritis and other orthopaedic diseases generate, The research majority of such disease is completed by zoopery.It but is still at present one about the administration mode of subchondral bone A difficult point, to affect the development of subchondral bone experiment.It carries out being directed to subchondral bone administration mode still when basic research at present Based on so disposably being injected with syringe needle, which not can guarantee subchondral bone absorption of drugs, not account for topically effective The maintenance problem of drug concentration, if single administration be unable to satisfy experiment carry out, need carry out multiple dosing, convenient administration mode into The infection probability of subchondral bone is increased while row multiple dosing, while syringe repeatedly enters subchondral bone, under cartilage The structure of bone will also result in destruction.
Utility model content
The technical problem to be solved by the utility model is to provide orthopaedics implantable drug delivery system, by by the drug delivery device It is fixed at administering position, realization continues quantitative subchondral bone administration.
Used technical solution to solve above-mentioned technical problem:
Orthopaedics implantable drug delivery system, including administration sleeve and the administration needle being inserted into the administration sleeve, the administration Needle connects administration pump by perfusion tube, and the administration needle includes the fixing head of needle tubing and fixed needle tubing, the fixing head with it is described The inner wall of administration sleeve is fixed.
Further, the fixing head and the inner wall of the administration sleeve are threadably secured.
Further, the outer wall of the administration sleeve is disposed with screw thread.
Further, the outer wall of the administration sleeve is taper, what the administration needle was relatively large in diameter from the administration sleeve One end insertion.
Further, the administration pump is flat.
Further, the length of the administration sleeve is greater than the length of the needle tubing.
Further, the bearing of the fixing head and the administration sleeve is disposed with sealing ring.
The utility model has the advantages that the utility model design administration needle insertion administration sleeve, is implanted into subchondral bone for administration sleeve, passes through Feeding drug of the administration pump through the lasting slow constant speed of administration needle replaces the mode disposably injected, and can avoid because of syringe Repeatedly enter subchondral bone and the structure of subchondral bone is caused to be destroyed, the input drug of sustainable slow constant speed.This Utility model can be widely applied to medical instruments field, it can be achieved that subchondral bone is administered at regular time and quantity, while avoiding traditional cartilage When sending down the fishbone disposably injects or is embedded to drug drug release can not quantify and unstability.At present in the animal of Osteoarthritis , it can be achieved that the administration at regular time and quantity of subchondral bone in experimental study;Future detects premature arthritis patient and magnetic resonance Subchondral bone has the patient of early stage cystic lesion, can be administered at regular time and quantity by this device in patient's subchondral bone, be controlled with reaching Treat the purpose of early stage Osteoarthritis.Meanwhile the device is not limited to the administration of Osteoarthritis subchondral bone, for long bone of limbs Office similarly can be achieved in small-molecule drug, protein medicine-feeding and stem-cell therapy of the diseases such as tumour, osteoporosis, infection etc. Portion is administered at regular time and quantity.
Detailed description of the invention
Fig. 1 is the cross-sectional view that sleeve is administered;
Fig. 2 is the structure chart of administration needle.
Appended drawing reference: 1, administration needle;2, sleeve is administered.
Specific embodiment
The utility model is described further below with reference to Fig. 1 and Fig. 2.
Orthopaedics implantable drug delivery system, it is described to give including administration sleeve 2 and the administration needle 1 being inserted into the administration sleeve 2 Medicine needle 1 connects administration pump by perfusion tube, and the administration pump is flat miniature administration pump.Administration sleeve 2 is implanted into cartilage Sending down the fishbone installs required dose in advance in administration pump, and administration pump is implanted into lateral of tibia edge and fixation.Therefore, administration pump passes through Administration needle 1 is sustainable to be slowly sent into drug in subchondral bone by certain flow rate, maintains subchondral bone within the medical time Constant dosage and administration concentration, reaches good administering effect.By the drug delivery device, the administration of a period of time can be met Demand avoids repeatedly carrying out needle injection administration, reduces to subchondral bone structural damage, will not influence skeletal structure Normal growth restores.
The administration needle 1 includes the fixing head of needle tubing and fixed needle tubing, the inner wall of the fixing head and the administration sleeve 2 Fixed, the fixing head and the inner wall of the administration sleeve 2 are threadably secured.The fixing head and the administration sleeve 2 Bearing is disposed with sealing ring, can prevent drug leakage.
The outer wall of the administration sleeve 2 is disposed with screw thread, the position of convenient administration sleeve 2 fixed in implantation.For convenient for Be administered sleeve 2 be implanted into, it is described administration sleeve 2 outer wall be taper, and the administration needle 1 from diameter on the administration sleeve 2 compared with Big one end insertion.
The length of the administration sleeve 2 is greater than the length of the needle tubing, and the needle tubing will not be from the end of the administration sleeve 2 End protrusion is exposed in subchondral bone, can not only prevent needle tubing from being blocked by tissue, but also can prevent needle tubing prick into human body from organizing.
In the present embodiment, used administration pump is common administration pump in medical treatment.The specific working principle is as follows: the administration Pump is divided into two side rooms and a middle room, and room is disposed with elastic membrane in administration pump, during infusion of medicine administration pump, elastic membrane It is extruded and opens.After drug fills, by the elastic recovery force of elastic membrane, the drug injected is exported outward.Pass through administration Circuit design inside pump can be such that the administration flow velocity of the administration pump fixes, such as monthly 50 microlitres of administration flow velocity.
The embodiments of the present invention is explained in detail in conjunction with attached drawing above, but the utility model is not limited to State embodiment, within the scope of knowledge possessed by those of ordinary skill in the art, can also do not depart from it is practical Various changes can be made under the premise of novel objective.

Claims (7)

1. orthopaedics implantable drug delivery system, it is characterised in that: including in administration sleeve (2) and the insertion administration sleeve (2) Administration needle (1), the administration needle (1) connect administration pump by perfusion tube, and the administration needle (1) includes needle tubing and fixed needle tubing Fixing head, the fixing head and the inner wall of administration sleeve (2) are fixed.
2. orthopaedics implantable drug delivery system according to claim 1, it is characterised in that: the fixing head and the administering cover The inner wall of cylinder (2) is threadably secured.
3. orthopaedics implantable drug delivery system according to claim 1, it is characterised in that: the outer wall of administration sleeve (2) It is disposed with screw thread.
4. orthopaedics implantable drug delivery system according to claim 1, it is characterised in that: the outer wall of administration sleeve (2) For taper, one end that the administration needle (1) is relatively large in diameter from administration sleeve (2) is inserted into.
5. orthopaedics implantable drug delivery system according to claim 1, it is characterised in that: the administration pump is flat.
6. orthopaedics implantable drug delivery system according to claim 1, it is characterised in that: the length of administration sleeve (2) Greater than the length of the needle tubing.
7. orthopaedics implantable drug delivery system according to claim 1, it is characterised in that: the fixing head and the administering cover The bearing of cylinder (2) is disposed with sealing ring.
CN201820198285.8U 2018-02-02 2018-02-02 Orthopaedics implantable drug delivery system Active CN209270606U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201820198285.8U CN209270606U (en) 2018-02-02 2018-02-02 Orthopaedics implantable drug delivery system

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201820198285.8U CN209270606U (en) 2018-02-02 2018-02-02 Orthopaedics implantable drug delivery system

Publications (1)

Publication Number Publication Date
CN209270606U true CN209270606U (en) 2019-08-20

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN201820198285.8U Active CN209270606U (en) 2018-02-02 2018-02-02 Orthopaedics implantable drug delivery system

Country Status (1)

Country Link
CN (1) CN209270606U (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108245771A (en) * 2018-02-02 2018-07-06 南方医科大学南方医院 Orthopaedics implantable drug delivery system
CN113058107A (en) * 2021-05-06 2021-07-02 南京佑羲医药科技有限公司 Anchor type long-acting analgesia pump device implanted in vivo

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108245771A (en) * 2018-02-02 2018-07-06 南方医科大学南方医院 Orthopaedics implantable drug delivery system
CN113058107A (en) * 2021-05-06 2021-07-02 南京佑羲医药科技有限公司 Anchor type long-acting analgesia pump device implanted in vivo
CN113058107B (en) * 2021-05-06 2023-02-21 南京佑羲医药科技有限公司 Anchor type long-acting analgesia pump device implanted in vivo

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