CN209203208U - A kind of imaging scope - Google Patents

A kind of imaging scope Download PDF

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Publication number
CN209203208U
CN209203208U CN201821685360.XU CN201821685360U CN209203208U CN 209203208 U CN209203208 U CN 209203208U CN 201821685360 U CN201821685360 U CN 201821685360U CN 209203208 U CN209203208 U CN 209203208U
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imaging
optical path
beam splitter
dichroscope
light
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Chinese (zh)
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杨西斌
熊大曦
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Suzhou Institute of Biomedical Engineering and Technology of CAS
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Suzhou Institute of Biomedical Engineering and Technology of CAS
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  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)

Abstract

The utility model discloses a kind of imaging scopes, including light source, lens group, imaging fibre, face to be imaged and image device, wherein, the image device includes for the first imagery device of light field imaging and for the second imagery device of fluorescence imaging, the first imagery device includes beam splitter and the first sub- device of imaging, the second imagery device includes dichroscope and the second sub- device of imaging, the beam splitter or dichroscope receive the light that the light source issues, the lens group, imaging fibre and face to be imaged are successively set in the reflected light optical path of the beam splitter or dichroscope, the sub- device of first imaging is arranged in the transmitted light optical path of beam splitter, the sub- device of second imaging is arranged in the optical path of incident light and transmitted light optical path of dichroscope.Compared with prior art, the utility model can realize nucleus or the imaging of other subcellular organelles by switching mode, and can be improved to the pathological changes diagnosis accuracy such as tumour.

Description

A kind of imaging scope
Technical field
The utility model belongs to clinical endoscopy technical field, and in particular to a kind of imaging scope.
Background technique
Clinical endoscopy technical field crosses imaging scope to the diagnosis multi-pass of the lesions such as tumour to realize, finding one kind can Realize light field imaging or fluorescence imaging, raising is technology urgently to be solved to the imaging scope of the accuracy of the pathological changes diagnosis such as tumour Problem.
Utility model content
The shortcomings that for the above-mentioned prior art or deficiency, the technical problem to be solved by the present invention is to provide one kind can Light field imaging or fluorescence imaging are realized by switching mode to be imaged and be can be improved to tumour to nucleus or other subcellular organelles The imaging scope of equal pathological changes diagnosis accuracy.
In order to solve the above technical problems, the utility model has following constitute:
A kind of imaging scope, including light source, lens group, imaging fibre, face to be imaged and image device, wherein described Image device includes for the first imagery device of light field imaging and for the second imagery device of fluorescence imaging described first Image device includes beam splitter and the first sub- device of imaging, and the second imagery device includes dichroscope and the second sub- device of imaging Part, the beam splitter or dichroscope receive the light that the light source issues, the lens group, imaging fibre and face to be imaged according to In the secondary reflected light optical path that the beam splitter or dichroscope is arranged in, the saturating of beam splitter is arranged in the sub- device of first imaging It penetrates in light optical path, the sub- device of second imaging is arranged in the optical path of incident light and transmitted light optical path of dichroscope.
The sub- device of first imaging includes the first imaging len and the first detector, first imaging len and the One detector is successively set in the transmitted light optical path of the beam splitter.
The sub- device of second imaging includes fluorescence excitation piece, fluorescent emission piece, the second imaging len and the second detection Device, the fluorescence excitation piece are arranged in the optical path between the light source and dichroscope, the fluorescent emission piece, the second imaging Lens and the second detector are successively set in the transmitted light optical path of the dichroscope.
Different installation positions is arranged in by changeable microscope base respectively in the beam splitter and dichroscope, the beam splitter and Dichroscope receives the light that different light sources issue respectively;It is equipped between the beam splitter and the installation position of dichroscope for connecing It receives and multiple reflecting mirrors of reflected light, one of reflecting mirror is disposed adjacent with the beam splitter and by changeable microscope base settings In the transmitted light optical path of the beam splitter, the reflecting mirror being disposed adjacent with dichroscope receives the reflection of upper level reflecting mirror Light, and by the reflected light back to the dichroscope.
The beam splitter and the reflecting mirror being disposed adjacent with the beam splitter select a switching in the optical path.
The beam splitter and dichroscope respectively by changeable microscope base setting in identical installation position, the beam splitter and Dichroscope receives the light of same light source sending respectively;One is equipped in optical path between the light source and dichroscope to be mounted on Fluorescence on changeable microscope base excites piece;Optical path between the beam splitter and the first sub- device of imaging is mounted on equipped with one can Switch the reflecting mirror on microscope base, light is reflexed to the second sub- imager through at least one other reflecting mirror by the reflected light of reflecting mirror Part.
The beam splitter and dichroscope select a switching in the optical path;It is described when the beam splitter switches in the optical path Fluorescence excitation piece and the reflecting mirror being disposed adjacent with the dichroscope are away from optical path;When the fluorescence excite piece, two to The switching of Look mirror and the reflecting mirror being disposed adjacent with the dichroscope in the optical path when, the beam splitter leaves optical path.
The first imagery device and second imagery device are the overall structure being mounted on switching mechanism, wherein institute State the light that the dichroscope in beam splitter or second imagery device in first imagery device receives same light source sending respectively.
First detector is colored or black-white CCD/CMOS camera.
Second detector is scientific research grade Weak photodetector.
Compared with prior art, the utility model has the following technical effect that
The fusion of light field imaging and fluorescence imaging may be implemented in the utility model, by an electronically or mechanically switching mode same Realize that light field imaging or fluorescence imaging nucleus or other subcellular organelles to be imaged, substantially increase and face in one scope Field is peeped to the diagnostic accuracy of the lesions such as tumour in bed.
Detailed description of the invention
By reading a detailed description of non-restrictive embodiments in the light of the attached drawings below, the application's is other Feature, objects and advantages will become more apparent upon:
Fig. 1: the schematic diagram of the utility model imaging the first embodiment of scope;
Fig. 2: the schematic diagram under light field imaging pattern as shown in Figure 1;
Fig. 3: the schematic diagram under fluorescence imaging mode as shown in Figure 2;
Fig. 4: the schematic diagram of the utility model imaging second of embodiment of scope;
Fig. 5: the schematic diagram under light field imaging pattern as shown in Figure 4;
Fig. 6: the schematic diagram under fluorescence imaging mode as shown in Figure 4;
Fig. 7: the schematic diagram one of the utility model imaging the third embodiment of scope;
Fig. 8: the schematic diagram two of the utility model imaging the third embodiment of scope.
Specific embodiment
Make furtherly below with reference to technical effect of the attached drawing to the design of the utility model, specific structure and generation It is bright, to be fully understood from the purpose of this utility model, feature and effect.
Embodiment one
A kind of imaging scope, including light source 10, lens group 20, imaging fibre 30, face to be imaged and image device, In, the image device include for the first imagery device of light field imaging and for the second imagery device of fluorescence imaging, The first imagery device includes beam splitter 40 and the first sub- device of imaging, and the second imagery device includes 50 He of dichroscope The second sub- device of imaging, the beam splitter 40 or dichroscope 50 receive the light that the light source 10 issues, the lens group 20, at It is successively set on as optical fiber 30 and face to be imaged in the reflected light optical path of the beam splitter 40 or dichroscope 50, described first Sub- device is imaged to be arranged in the transmitted light optical path of beam splitter 40, entering for dichroscope 50 is arranged in the sub- device of second imaging It penetrates in light optical path and transmitted light optical path.
The sub- device of first imaging includes the first imaging len 41 and the first detector 42, first imaging len 41 And first detector 42 be successively set in the transmitted light optical path of the beam splitter 40.
The sub- device of second imaging includes fluorescence excitation piece 52, fluorescent emission piece 53, the second imaging len 54 and the Two detectors 55, the fluorescence excitation piece 52 are arranged in the optical path between the light source 10 and dichroscope 50, the fluorescence Sheet emitting 53, the second imaging len 54 and the second detector 55 are successively set on the transmitted light optical path of the dichroscope 50 On.
Different installation positions, the beam splitting is arranged in by changeable microscope base respectively in the beam splitter 40 and dichroscope 50 Mirror 40 and dichroscope 50 receive the light that different light sources 10 issue respectively;In the installation position of the beam splitter 40 and dichroscope 50 Between be equipped with for receives with multiple reflecting mirrors 51 of reflected light, one of reflecting mirror 51 is disposed adjacent with the beam splitter 40 And it is arranged in the 40 transmitted light optical path of beam splitter by changeable microscope base, the reflecting mirror 51 being disposed adjacent with dichroscope 50 The reflected light of upper level reflecting mirror 51 is received, and by the reflected light back to the dichroscope 50.The beam splitter 40 and The reflecting mirror 51 being disposed adjacent with the beam splitter 40 selects a switching in the optical path.
As shown in Figure 1, beam splitter 40 in dotted line frame and the reflecting mirror 51 being disposed adjacent with the beam splitter 40 are respectively mounted On changeable microscope base, optical path can be located in optical path or left by an electronically or mechanically mode, in system work, Beam splitter 40 and reflecting mirror 51 are not located in optical path simultaneously, and only alternative one is located in optical path.
In the present embodiment, the setting quantity of light source 10 is two, and beam splitter 40 is 50% beam splitter.The light source 10 wraps Include LED light source, laser light source, xenon source, halogen light source etc..
As shown in Fig. 2, adjusting changeable microscope base under light field imaging pattern by an electronically or mechanically mode, making beam splitter 40 are located in optical path, and the reflecting mirror 51 being disposed adjacent with the beam splitter 40 is not in the optical path.Specifically, one of light source 10 The light of sending reflects, at this time light energy losses 50% by beam splitter 40, and the light energy of residue 50% passes through lens group 20 or mesh Mirror focuses on the end face of imaging fibre 30, conducts by the light of imaging optical fiber bundle 30, light energy eventually arrives at face to be imaged;Root It is returned by the light that face to be imaged is reflected by same optical path according to reversibility of optical path principle, reaches beam splitter 40, at this time luminous energy Amount loss 50% again, the light energy of residue 50% continue along paths, by the first imaging len 41, in the first detector 42 Upper imaging.
It is colored or black-white CCD/CMOS camera that wherein the first detector 42, which is the CCD, forms black surround or color image.Example Such as in Methylene Blue stained cells, the colour imaging of nucleus may be implemented by the light field imaging pattern.
As shown in figure 3, adjusting changeable microscope base under fluorescence imaging mode by an electronically or mechanically mode, making reflecting mirror 51 are located in optical path, and beam splitter 40 is then not in the optical path.Specifically, the light that another light source 10 issues, excites piece by fluorescence 52 filtering, form narrowband excitation light, which is reflected by dichroscope 50, and continuously anti-by two steering reflection mirrors 51 It penetrates, is incident in lens group 20 or eyepiece, focused on by lens group 20 or eyepiece on the end face of imaging fibre 30, by imaging The light of optical fiber 30 conducts, and light energy eventually arrives at excitation fluorescence in face to be imaged;According to reversibility of optical path principle, fluorescence is excited to pass through Same optical path returns, and reflects again through two steering reflection mirrors 51, reaches dichroscope 50, and fluorescence penetrates dichroic at this time Mirror 50, and filtered by fluorescent emission piece 53, only excitation fluorescence is imaged on the second detector 55 by the second imaging len 54, Form fluorescent image.
Due to fluorescence be pole dim light, second detector 55 be scientific research grade Weak photodetector, be electron gain CCD or Scientific research grade cmos detector.Such as in the cell of fluorescein sodium dyeing, subcellular may be implemented by the fluorescence imaging mode Horizontal fluorescent image.
The present embodiment only passes through the changeable design of beam splitter 40 and one of reflecting mirror 51 in the optical path, so that it may Realize that fluorescence imaging is switched fast with what light field was imaged, switching mode is simple to operation and stable system performance, to diseases such as tumours The accuracy rate of diagnosis of change is high.
Embodiment two
A kind of imaging scope, including light source 10, lens group 20, imaging fibre 30, face to be imaged and image device, In, the image device include for the first imagery device of light field imaging and for the second imagery device of fluorescence imaging, The first imagery device includes beam splitter 40 and the first sub- device of imaging, and the second imagery device includes 50 He of dichroscope The second sub- device of imaging, the beam splitter 40 or dichroscope 50 receive the light that the light source 10 issues, the lens group 20, at It is successively set on as optical fiber 30 and face to be imaged in the reflected light optical path of the beam splitter 40 or dichroscope 50, described first Sub- device is imaged to be arranged in the transmitted light optical path of beam splitter 40, entering for dichroscope 50 is arranged in the sub- device of second imaging It penetrates in light optical path and/or transmitted light optical path, wherein the incident light light of dichroscope 50 is arranged in fluorescence excitation piece 52 described below On the road, the fluorescent emission piece 53, the second imaging len 54 and the second detector 55 are successively set on the dichroscope 50 Transmitted light optical path on.
The sub- device of first imaging includes the first imaging len 41 and the first detector 42, first imaging len 41 And first detector 42 be successively set in the transmitted light optical path of the beam splitter 40.
The sub- device of second imaging includes fluorescence excitation piece 52, fluorescent emission piece 53, the second imaging len 54 and the Two detectors 55, the fluorescence excitation piece 52 are arranged in the optical path between the light source 10 and dichroscope 50, the fluorescence Sheet emitting 53, the second imaging len 54 and the second detector 55 are successively set on the transmitted light optical path of the dichroscope 50 On.
The beam splitter 40 and dichroscope 50 are arranged by changeable microscope base in identical installation position, the beam splitting respectively Mirror 40 and dichroscope 50 receive the light of the sending of same light source 10 respectively;Optical path between the light source 10 and dichroscope 50 It is equipped with a fluorescence excitation piece 52 being mounted on changeable microscope base;Light between the beam splitter 40 and the first sub- device of imaging Road is equipped with a reflecting mirror 51 being mounted on changeable microscope base, and the reflected light of reflecting mirror 51 is through at least one other reflecting mirror Light is reflexed to the second sub- image device by 51.
The beam splitter 40 and dichroscope 50 select a switching in the optical path;When the beam splitter 40 switches in the optical path When, the fluorescence excitation piece 52 and the reflecting mirror 51 being disposed adjacent with the dichroscope 50 are away from optical path;When described glimmering Light excites the switching of piece 52, dichroscope 50 and the reflecting mirror 51 being disposed adjacent with the dichroscope 50 in the optical path When, the beam splitter 40 leaves optical path.
In the present embodiment, the setting quantity of the light source 10 is one, and beam splitter 40 is 50% beam splitter.The light source 10 include LED light source, laser light source, xenon source, halogen light source etc..
As shown in figure 4, wherein the fluorescence in dotted line frame excites piece 52, reflecting mirror 51, beam splitter 40 and dichroscope 50 It is installed on changeable microscope base, wherein beam splitter 40 and dichroscope 50, which can be switched, is mounted on same installation position, Ke Yitong Crossing an electronically or mechanically mode and adjusting changeable microscope base makes fluorescence excitation piece 52, reflecting mirror 51, beam splitter 40 and dichroscope 50 In optical path or leave optical path.
It working in both modes in system, the first mode is light field imaging pattern, and beam splitter 40 is located in optical path, and Fluorescence excites piece 52, dichroscope 50 and reflecting mirror 51 not to be located in optical path;Second of mode is fluorescence imaging mode, and fluorescence swashs Send out piece 52, dichroscope 50 and reflecting mirror 51 are located in optical path simultaneously, beam splitter 40 is not in the optical path.
As shown in figure 5, adjusting changeable microscope base under light field imaging pattern by an electronically or mechanically mode, making beam splitter 40 are located in optical path, and fluorescence excites piece 52, dichroscope 50 and reflecting mirror 51 not to be located in optical path.Specifically, one of light The light that source 10 issues reflects, at this time light energy losses 50% by beam splitter 40, and the light energy of residue 50% passes through lens group 20 Or eyepiece focuses on the end face of imaging fibre 30, conducts by the light of imaging fibre 30, light energy eventually arrives at face to be imaged; It is returned by the light that face to be imaged is reflected by same optical path according to reversibility of optical path principle, reaches beam splitter 40, this time Energy loses 50% again, and the light energy of residue 50% continues to conduct along optical path, by the first imaging len 41, in the first detector It is imaged on 42.
It is colored or black-white CCD/CMOS camera that wherein the first detector 42, which is the CCD, forms black surround or color image.Example Such as in Methylene Blue stained cells, the colour imaging of nucleus may be implemented by the light field imaging pattern.
As shown in fig. 6, changeable microscope base is adjusted by an electronically or mechanically mode, so that fluorescence under fluorescence imaging mode Piece 52, dichroscope 50 and reflecting mirror 51 is excited to be located in optical path simultaneously, beam splitter 40 is not in the optical path.Specifically, light source 10 The light of sending filters by fluorescence excitation piece 52, forms narrowband excitation light, which is reflected by dichroscope 50, directly Access is mapped in lens group 20 or eyepiece, is focused on 30 end face of imaging fibre by lens group 20 or eyepiece, by imaging The light conduction of fibre 30, light energy eventually arrive at excitation fluorescence in face to be imaged;According to reversibility of optical path principle, fluorescence is excited to pass through phase Same light path returns, and reaches dichroscope 50, and fluorescence penetrates dichroscope 50 at this time, is reflected by two steering reflection mirrors 51, and by Fluorescent emission piece 53 filters, and only excitation fluorescence is imaged on the second detector 55 by the second imaging len 54, forms fluorescence Image.
Due to fluorescence be pole dim light, second detector 55 be scientific research grade Weak photodetector, be electron gain CCD or Scientific research grade cmos detector.Such as in the cell of fluorescein sodium dyeing, subcellular may be implemented by the fluorescence imaging mode Horizontal fluorescent image.
The present embodiment only uses a light source 10, reduces components, so that overall structure is more compact;And fluorescence Excite piece 52, reflecting mirror 51, the changeable design of beam splitter 40 and dichroscope 50 in the optical path, so that it may realize fluorescence at As being switched fast with light field imaging, switching mode is simple to operation and stable system performance, quasi- to the diagnosis of the lesions such as tumour True rate is high.
Embodiment three
A kind of imaging scope, including light source 10, lens group 20, imaging fibre 30, face to be imaged and image device, In, the image device include for the first imagery device of light field imaging and for the second imagery device of fluorescence imaging, The first imagery device includes beam splitter 40 and the first sub- device of imaging, and the second imagery device includes 50 He of dichroscope The second sub- device of imaging, the beam splitter 40 or dichroscope 50 receive the light that the light source 10 issues, the lens group 20, at It is successively set on as optical fiber 30 and face to be imaged in the reflected light optical path of the beam splitter 40 or dichroscope 50, described first Sub- device is imaged to be arranged in the transmitted light optical path of beam splitter 40, entering for dichroscope 50 is arranged in the sub- device of second imaging It penetrates in light optical path and transmitted light optical path.
The sub- device of first imaging includes the first imaging len 41 and the first detector 42, first imaging len 41 And first detector 42 be successively set in the transmitted light optical path of the beam splitter 40.
The sub- device of second imaging includes fluorescence excitation piece 52, fluorescent emission piece 53, the second imaging len 54 and the Two detectors 55, the fluorescence excitation piece 52 are arranged in the optical path between the light source 10 and dichroscope 50, the fluorescence Sheet emitting 53, the second imaging len 54 and the second detector 55 are successively set on the transmitted light optical path of the dichroscope 50 On.
In the present embodiment, the setting quantity of the light source 10 is one, and beam splitter 40 is 50% beam splitter.The light source 10 include LED light source, laser light source, xenon source, halogen light source etc..
In the present embodiment, the first imagery device and second imagery device are the entirety being mounted on switching mechanism Structure, wherein the beam splitter 40 in the first imagery device or the dichroscope in second imagery device 50 receive together respectively The light that one light source 10 issues.It can realize that the entirety of element in two dotted line frames is cut by motorized precision translation stage or Mechanical Moving platform It changes.There is also two kinds of operating modes, respectively light field imaging pattern and fluorescence imaging mode for the embodiment.
As described in Figure 7, under light field imaging pattern, the element in the dotted line frame is switched in optical path.Specifically, wherein The light that one light source 10 issues reflects, at this time light energy losses 50% by beam splitter 40, and the light energy of residue 50% passes through mirror Head group 20 or eyepiece focus on the end face of imaging fibre 30, by imaging fibre 30 light conduct, light energy eventually arrive to Imaging surface;It is returned by the light that face to be imaged is reflected by same optical path according to reversibility of optical path principle, reaches beam splitter 40, Light energy loses 50% again at this time, and the light energy of residue 50% continues along paths, by the first imaging len 41, first It is imaged on detector 42.
It is colored or black-white CCD/CMOS camera that wherein the first detector 42, which is the CCD, forms black surround or color image.Example Such as in Methylene Blue stained cells, the colour imaging of nucleus may be implemented by the light field imaging pattern.
As shown in figure 8, the element in the dotted line frame is switched in optical path under fluorescence imaging mode.Specifically, light source 10 light issued filter by fluorescence excitation piece 52, form narrowband excitation light, which is reflected by dichroscope 50, Be directly incident in lens group 20 or eyepiece, focused on by lens group 20 or eyepiece on the end face of imaging fibre 30, by As the light conduction of optical fiber 30, light energy eventually arrives at excitation fluorescence in face to be imaged;According to reversibility of optical path principle, fluorescence warp is excited Same optical path return is crossed, dichroscope 50 is reached, fluorescence penetrates dichroscope 50 at this time, and is filtered by fluorescent emission piece 53, only There is excitation fluorescence to be imaged on the second detector 55 by the second imaging len 54, forms fluorescent image.The structure equally can be with Subcellsular level fluorescence imaging applied to fluorescein sodium dyeing.
Advantage of this embodiment is that the element in dotted line frame under two kinds of imaging patterns is whole changeable design, principle letter It is single, it realizes more convenient.
Above embodiments are only to illustrate the technical solution of the utility model and non-limiting, referring to preferred embodiment to this reality It is described in detail with novel.Those skilled in the art should understand that can be to the technical solution of the utility model It modifies or equivalent replacement should all cover practical new at this without departing from the spirit and scope of the technical scheme of the present invention In the scope of the claims of type.

Claims (10)

1. a kind of imaging scope, which is characterized in that
Including light source (10), lens group (20), imaging fibre (30), face to be imaged and image device, wherein the imager Part include for the first imagery device of light field imaging and for the second imagery device of fluorescence imaging,
The first imagery device includes beam splitter (40) and the first sub- device of imaging, and the second imagery device includes dichroic Mirror (50) and the second sub- device of imaging,
The beam splitter (40) or dichroscope (50) receive the light that the light source (10) issues,
The lens group (20), imaging fibre (30) and face to be imaged are successively set on the beam splitter (40) or dichroscope (50) in reflected light optical path,
The sub- device of first imaging is arranged in the transmitted light optical path of beam splitter (40), and the sub- device setting of the second imaging exists In the optical path of incident light and transmitted light optical path of dichroscope (50).
2. imaging scope according to claim 1, which is characterized in that the sub- device of first imaging includes that the first imaging is saturating Mirror (41) and the first detector (42), first imaging len (41) and the first detector (42) are successively set on described point In the transmitted light optical path of Shu Jing (40).
3. imaging scope according to claim 1, which is characterized in that the sub- device of second imaging includes fluorescence excitation piece (52), fluorescent emission piece (53), the second imaging len (54) and the second detector (55), fluorescence excitation piece (52) setting In optical path between the light source (10) and dichroscope (50), the fluorescent emission piece (53), the second imaging len (54) And second detector (55) be successively set in the transmitted light optical path of the dichroscope (50).
4. imaging scope according to any one of claims 1 to 3, which is characterized in that
Different installation positions, the beam splitting is arranged in by changeable microscope base respectively in the beam splitter (40) and dichroscope (50) Mirror (40) and dichroscope (50) receive the light that different light sources (10) issue respectively;
It is equipped between the beam splitter (40) and the installation position of dichroscope (50) for receiving and multiple reflections of reflected light Mirror (51),
One of reflecting mirror (51) is disposed adjacent with the beam splitter (40) and is arranged by changeable microscope base in the beam splitting In mirror (40) transmitted light optical path,
The reflecting mirror (51) that is disposed adjacent with dichroscope (50) receives the reflected light of upper level reflecting mirror (51), and by the reflection Light reflexes to the dichroscope (50).
5. imaging scope according to claim 4, which is characterized in that the beam splitter (40) and with the beam splitter (40) reflecting mirror (51) being disposed adjacent selects a switching in the optical path.
6. imaging scope according to any one of claims 1 to 3, which is characterized in that the beam splitter (40) and dichroic Mirror (50) is arranged by changeable microscope base in identical installation position respectively, and the beam splitter (40) and dichroscope (50) connect respectively Receive the light that same light source (10) issue;
The fluorescence that one is mounted on changeable microscope base is equipped in optical path between the light source (10) and dichroscope (50) to swash Send out piece;
Optical path between the beam splitter (40) and the first sub- device of imaging is equipped with a reflection being mounted on changeable microscope base The reflected light of mirror (51), reflecting mirror (51) transmits light to the second sub- image device through at least one reflecting mirror (51).
7. imaging scope according to claim 6, which is characterized in that
The beam splitter (40) and dichroscope (50) select a switching in the optical path;
When the beam splitter (40) switching in the optical path when, fluorescence excitation piece and setting are in the beam splitter (40) and the Reflecting mirror (51) between the one sub- device of imaging switches away from optical path;
When the fluorescence excites piece (52), dichroscope (50) and the reflecting mirror being disposed adjacent with the dichroscope (50) (51) switching in the optical path when, the beam splitter (40) switches away from optical path.
8. imaging scope according to any one of claims 1 to 3, which is characterized in that the first imagery device and second Image device is the overall structure being mounted on switching mechanism, wherein beam splitter (40) in the first imagery device or Dichroscope (50) in second imagery device receives the light of same light source (10) sending respectively.
9. imaging scope according to claim 2, which is characterized in that first detector (42) is colored or black and white CCD/CMOS camera.
10. imaging scope according to claim 3, which is characterized in that second detector (55) is scientific research grade dim light Detector.
CN201821685360.XU 2018-10-17 2018-10-17 A kind of imaging scope Active CN209203208U (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109288490A (en) * 2018-10-17 2019-02-01 中国科学院苏州生物医学工程技术研究所 A kind of imaging scope
CN113768472A (en) * 2021-11-10 2021-12-10 华中科技大学 Three-dimensional image acquisition device with fluorescent marker and method

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109288490A (en) * 2018-10-17 2019-02-01 中国科学院苏州生物医学工程技术研究所 A kind of imaging scope
CN113768472A (en) * 2021-11-10 2021-12-10 华中科技大学 Three-dimensional image acquisition device with fluorescent marker and method

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Assignee: SHENYANG SHENDA ENDOSCOPE Co.,Ltd.

Assignor: Suzhou Institute of Biomedical Engineering and Technology Chinese Academy of Sciences

Contract record no.: X2020980005472

Denomination of utility model: An imaging endoscope

Granted publication date: 20190806

License type: Common License

Record date: 20200827

EE01 Entry into force of recordation of patent licensing contract