CN209193857U - A kind of albumen precipitation supernatant separation device - Google Patents
A kind of albumen precipitation supernatant separation device Download PDFInfo
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- CN209193857U CN209193857U CN201821921339.5U CN201821921339U CN209193857U CN 209193857 U CN209193857 U CN 209193857U CN 201821921339 U CN201821921339 U CN 201821921339U CN 209193857 U CN209193857 U CN 209193857U
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- settling tank
- probe tube
- tank
- separation device
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Abstract
The utility model provides a kind of albumen precipitation supernatant separation device.Specifically, the utility model provides a kind of albumen precipitation supernatant separation device, and the device includes settling tank, gas source, and the gas source is connected by gas pipeline with the settling tank；The tank skin of the settling tank is equipped with feed pipe, discharge nozzle, supernatant separation device and form；The supernatant separation device includes casing and probe tube, the casing passes through the upper tank skin of the settling tank, the probe tube passes through described sleeve pipe, between the probe tube and described sleeve pipe be tightly connected and can be free to slide, the lower ends bent of probe tube in the settling tank is at being parallel to the horizontal plane, the nozzle of probe tube in the settling tank is equipped with 30-60 ° of upper scarf, and the nozzle of the probe tube outside settling tank is equipped with diaphragm valve.The albumen precipitation supernatant separation device of the utility model can be realized albumen precipitation supernatant quick separating, easy to operate and guarantee product quality.
Description
Technical field
The utility model relates to bio-pharmaceuticals apparatus fields, and in particular to a kind of albumen precipitation supernatant separation device.
Background technique
In bio-pharmaceuticals separation and purification of protein, most of technique for using albumen precipitation carries out initial gross separation.But big
In scale processes, after albumen is sufficiently precipitated, need for supernatant a large amount of in material pot to be removed.Currently, using compared with
More is a piece hose of decentralization installation at the top of jar, is then extracted outside tank body with peristaltic pump, disadvantage of this is that
It is easy to suck up the precipitating of bottom, influences separating effect, and this separate mode easilys lead to the pollution of miscellaneous bacteria, thus
Albumen is polluted.
Therefore, this field needs to develop a kind of quick, easy to operate and guarantees the albumen precipitation supernatant that product quality requires
Liquid separating apparatus.
Utility model content
The purpose of this utility model is to provide albumen precipitations that is a kind of quick, easy to operate and guaranteeing product quality requirement
Supernatant separation device.
The utility model in a first aspect, provide a kind of albumen precipitation supernatant separation device, the device includes heavy
Shallow lake tank 10, gas source 20, the gas source are connected by gas pipeline 30 with the settling tank；
The tank skin of the settling tank is equipped with feed pipe 11, discharge nozzle 12, supernatant separation device and form 13；
The supernatant separation device includes casing 14 and probe tube 15, and the casing passes through the upper tank of the settling tank
Wall, the probe tube pass through described sleeve pipe, between the probe tube and described sleeve pipe be tightly connected and can be free to slide, institute
The lower ends bent of the probe tube in settling tank is stated at being parallel to the horizontal plane, the nozzle of the probe tube in the settling tank is equipped with 30-
60 ° are gone up scarves, and the nozzle of the probe tube outside settling tank is equipped with diaphragm valve 16.
In another preferred example, the lower end of the probe tube in the settling tank is vertically bent to be parallel to the horizontal plane.
In another preferred example, the discharge nozzle is located at the bottom of the settling tank.
In another preferred example, the casing length is identical as the wall thickness of upper tank skin of settling tank.
In another preferred example, the casing is fixedly connected on the upper tank skin of the settling tank.
In another preferred example, the gas source is compressed air source.
In another preferred example, the bottom of the settling tank is pyramidal structure, and the discharge nozzle is arranged in settling tank
Bottom.
In another preferred example, the pyramidal structure is arc-shaped pyramidal structure.
In another preferred example, form longitudinal arrangement on the tank skin of settling tank.
In another preferred example, the form is transparent window.
In another preferred example, the form is transparent class visual window.
In another preferred example, the probe tube and described sleeve pipe are stereoplasm tube.
In another preferred example, the diaphragm valve is sanitary diaphragm valve.
In another preferred example, the settling tank is equipped with height-adjustable support frame, for placing probe tube.
In another preferred example, liquid filter 17 is additionally provided on the probe tube outside the settling tank.
In another preferred example, the gas pipeline of crossing is additionally provided with air filter 31.
In another preferred example, the feed pipe and discharge nozzle are equipped with valve 18.
In another preferred example, the settling tank is additionally provided with heater.
It should be understood that in the scope of the utility model, above-mentioned each technical characteristic of the utility model and (strictly according to the facts below
Apply example) in specifically describe each technical characteristic between can be combined with each other, to form a new or preferred technical solution.Limit
In length, not repeated them here.
Detailed description of the invention
The attached figures are only used for illustrative purposes and cannot be understood as limitating the patent；In order to better illustrate this embodiment, attached
Scheme certain components to have omission, zoom in or out, does not represent the size of actual product；To those skilled in the art,
The omitting of some known structures and their instructions in the attached drawings are understandable；The same or similar label corresponds to same or similar
Component；The terms describing the positional relationship in the drawings are only for illustration, should not be understood as the limitation to this patent.
Fig. 1 is albumen precipitation supernatant separation apparatus structure schematic diagram in a preference of the utility model.
Wherein, attached drawing respectively numbers representative:
10 be settling tank, 11 be feed pipe, 12 be discharge nozzle, 13 be form, 14 be casing, 15 be probe tube, 16 for every
Film valve, 17 be liquid filter, 18 be valve, 20 be gas source, 30 be gas pipeline and 31 be air filter.
Specific embodiment
The present inventor develops a kind of albumen precipitation supernatant separation device by extensive and in-depth study.At this
In albumen precipitation supernatant separation device described in utility model, between probe tube and described sleeve pipe be tightly connected and can be free
Therefore sliding can make nozzle be located at supernatant and protein precipitation circle by the height of the nozzle of the probe tube in adjusting settling tank
The height in face leads to gas pressurized into settling tank by gas source, by the effect of air pressure supernatant is discharged, to realize
Albumen precipitation supernatant separation, albumen precipitation supernatant separation device described in the utility model have quick separating, operation letter
Single and guarantee product quality requires advantage.On this basis, inventor completes the utility model.
Term
Unless otherwise defined, belonging to the meaning and the utility model of all technical and scientific terms used herein
The meaning that field those of ordinary skill is commonly understood by is identical.
As used herein, the terms "include", "comprise" are used interchangeably with " containing ", not only include open definition, also
Including semi-enclosed and closed definition.In other words, the term include " by ... constitute ", " substantially by ... structure
At ".
As used herein, the orientation or positional relationship of the instructions such as term " on ", "lower", "top", "bottom", "horizontal" be based on
Orientation or positional relationship shown in the drawings is merely for convenience of description the utility model and creates and simplify description, rather than indicates
Or imply that signified device or element must have a particular orientation, be constructed and operated in a specific orientation, therefore cannot understand
For the restriction created to the utility model.
As used herein, term " connection " is to be understood broadly, and may be a fixed connection, and is also possible to detachably connect
It connects, or is integrally connected.
As used herein, term " albumen precipitation supernatant separation device " is used interchangeably with " device ".
For ease of description, further describe the utility model below in conjunction with attached drawing 1, in the utility model it should be understood that
It is that attached drawing does not limit the scope of the utility model.
Typically, the utility model provides a kind of albumen precipitation supernatant separation device, which is characterized in that the device
Including settling tank 10, gas source 20, the gas source is connected by gas pipeline 30 with the settling tank；
The tank skin of the settling tank is equipped with feed pipe 11, discharge nozzle 12, supernatant separation device and form 13；
The supernatant separation device includes casing 14 and probe tube 15, and the casing passes through the upper tank of the settling tank
Wall, the probe tube pass through described sleeve pipe, between the probe tube and described sleeve pipe be tightly connected and can be free to slide, institute
The lower ends bent of the probe tube in settling tank is stated at being parallel to the horizontal plane, the nozzle of the probe tube in the settling tank is equipped with 30-
60 ° are gone up scarves, and the nozzle of the probe tube outside settling tank is equipped with diaphragm valve 16.
In device described in the utility model, also sunk by the form that the tank skin of settling tank is equipped with to observe supernatant
The interface of shallow lake albumen.Preferably, the form is transparent window, and typically, the form is transparent class visual window.Another
In one preference, form longitudinal arrangement on the tank skin of settling tank.
In bio-pharmaceuticals separation and purification of protein, each inventory in precipitating filling is often different, leads to each supernatant
Different from the interfacial level of protein precipitation, in albumen precipitation supernatant separation device described in the utility model, described is taken
Between sample pipe and casing be tightly connected and can be free to slide, therefore, can by the sliding between probe tube and casing, adjust
The height of the nozzle of probe tube in settling tank makes the nozzle of the probe tube in settling tank be located at supernatant and protein precipitation interface
Between, to realize the supernatant of different interfacial levels and the separation requirement of protein precipitation.
In device described in the utility model, the nozzle of the probe tube in settling tank is equipped with 30-60 ° of upper scarf.With
Traditional circular ports are compared, and nozzle, which is equipped with 30-60 ° of upper scarf, can not only effectively improve the area of nozzle, improve supernatant
The rate of discharge of liquid, prevents nozzle from blocking, and the fluid dynamics of the nozzle of scarf and supernatant are adapted on 30-60 °,
The smooth flow for ensuring supernatant, preventing the not specification of supernatant from flowing causes albumen precipitation to be sucked up, and influences separating effect.
In device described in the utility model, gas source is connected by gas pipeline with the settling tank, can be passed through
Gas source is passed through gas into settling tank, pressurizes to the supernatant in settling tank, by the effect of air pressure by supernatant
Discharge.A piece hose of installation is transferred at the top of settling tank with tradition, is then extracted that (traditional is compacted outside tank body with peristaltic pump
Suction usually acts directly on protein precipitation in dynamic pump suction process, sucks up so as to cause by the protein precipitation of bottom) phase
Than device described in the utility model, air pressure directly acts on clear liquid and be pressurised into uniform pressurization of the gas to supernatant, energy
It is enough effectively to prevent from sucking up in the albumen of precipitating, guarantee separating effect.
It in device described in the utility model, is tightly connected between the probe tube and described sleeve pipe, is tightly connected energy
Enough guarantee that the miscellaneous bacteria in probe tube and described sleeve pipe sliding process in air cannot be introduced into settling tank, cause dirt to settling tank
Dye.In a preferred embodiment, the diaphragm valve is sanitary diaphragm valve.In another preferred example, taking outside the settling tank
Liquid filter 17 is additionally provided on sample pipe.In another preferred example, the gas pipeline of crossing is additionally provided with air filter.Health
The setting of diaphragm valve, liquid filter and/or air filter can further prevent during the separation process miscellaneous bacteria enter precipitating
In tank, so that the protein precipitation microbial contamination of settling tank, to guarantee the quality of protein precipitation.
In a preference in the utility model, the bottom of the settling tank is pyramidal structure, the discharging
The bottom of settling tank is arranged in pipe.Compared with traditional bottom is the settling tank of planar structure, bottom is the settling tank of pyramidal structure
It can guarantee that protein precipitation is smoothly flowed out from discharge nozzle, protein precipitation is avoided to collect not exclusively, to improve protein precipitation
Collection rate.
In another preferred example, the feed pipe and discharge nozzle are equipped with valve 18.
In another preferred example, the probe tube and described sleeve pipe are stereoplasm tube.
In another preferred example, the settling tank is equipped with height-adjustable support frame, for placing probe tube.
In another preferred example, the gas pipeline of crossing is additionally provided with air filter 31.
In another preferred example, the settling tank is additionally provided with heater.Heater adds the material in settling tank
Heat is guaranteed that the temperature during supernatant separation is kept in a certain range, can be reduced to avoid some supernatants due to temperature
Viscosity is caused to increase and be unfavorable for being discharged.
The major advantage of the utility model includes:
1, albumen precipitation supernatant separation device described in the utility model is capable of the upper of flexible adaptation difference interfacial level
The separation of clear liquid and protein precipitation
2, supernatant is discharged by way of gas pressurized for device described in the utility model, can effectively prevent by
The albumen of precipitating sucks up, and guarantees separating effect.
3, device described in the utility model can be avoided settling tank microbial contamination, to guarantee the precipitating isolated
The quality of albumen.
The present invention will be further illustrated below in conjunction with specific embodiments.It should be understood that these embodiments are merely to illustrate this
Utility model rather than limitation the scope of the utility model.In the following examples, the experimental methods for specific conditions are not specified, leads to
Often according to normal conditions, or according to the normal condition proposed by manufacturer.Unless otherwise stated, otherwise percentage and number be by weight
It calculates.
Embodiment 1
The present embodiment provides a kind of albumen precipitation supernatant separation device, the albumen precipitation supernatant separation device packet
It includes:
The device includes settling tank, gas source, and the gas source passes through gas pipeline and the settling tank phase
Even, the gas pipeline is additionally provided with air filter；
The bottom of the settling tank is pyramidal structure, and the bottom of settling tank is arranged in the discharge nozzle, and described is heavy
The tank skin of shallow lake tank is equipped with feed pipe, discharge nozzle, supernatant separation device, form and heater, and the form is transparent glass
Form and the longitudinal arrangement on the tank skin of settling tank, the feed pipe and discharge nozzle are equipped with valve；
The supernatant separation device includes casing and probe tube, and the casing passes through the upper tank skin of the settling tank,
The probe tube pass through described sleeve pipe, between the probe tube and described sleeve pipe be tightly connected and can be free to slide, precipitating
For the lower ends bent of probe tube in tank at being parallel to the horizontal plane, the nozzle of the probe tube in settling tank is equipped with 30-60 ° of upper beveling
Face, the nozzle of the probe tube outside settling tank are equipped with sanitary diaphragm valve, are additionally provided with liquid mistake on the probe tube outside the settling tank
Filter.
The working principle of the present embodiment aseptic inoculating device is as follows:
Material is entered in settling tank by feed inlet, after supernatant and protein precipitation layering, passes through probe tube and set
Sliding between pipe adjusts the height of the nozzle of the probe tube in settling tank, nozzle is made to be located at supernatant and protein precipitation interface
Between, gas source is passed through gas pressurized, the sanitary diaphragm valve discharge of supernatant sampled pipe under the influence of air pressure, to supernatant
After emptying, stopping is passed through gas, opens discharge nozzle, collecting precipitation protein.
It is incorporated herein by reference in all documents that the utility model refers to, just as each document quilt
It is individually recited as with reference to such.In addition, it should also be understood that, after having read the above-mentioned teaching content of the utility model, this field skill
Art personnel can make various changes or modifications the utility model, and such equivalent forms equally fall within the application appended claims
Book limited range.
Claims (10)
1. a kind of albumen precipitation supernatant separation device, which is characterized in that the device includes settling tank (10), gas source
(20), the gas source is connected by gas pipeline (30) with the settling tank；
The tank skin of the settling tank is equipped with feed pipe (11), discharge nozzle (12), supernatant separation device and form (13)；
The supernatant separation device includes casing (14) and probe tube (15), and the casing passes through the upper tank of the settling tank
Wall, the probe tube pass through described sleeve pipe, between the probe tube and described sleeve pipe be tightly connected and can be free to slide, institute
The lower ends bent of the probe tube in settling tank is stated at being parallel to the horizontal plane, the nozzle of the probe tube in the settling tank is equipped with 30-
60 ° are gone up scarves, and the nozzle of the probe tube outside settling tank is equipped with diaphragm valve (16).
2. device as described in claim 1, which is characterized in that the bottom of the settling tank is pyramidal structure, and described goes out
The bottom of settling tank is arranged in expects pipe.
3. device as described in claim 1, which is characterized in that form longitudinal arrangement on the tank skin of settling tank.
4. device as described in claim 1, which is characterized in that the form is transparent window.
5. device as described in claim 1, which is characterized in that the probe tube and described sleeve pipe are stereoplasm tube.
6. device as described in claim 1, which is characterized in that the diaphragm valve is sanitary diaphragm valve.
7. device as described in claim 1, which is characterized in that be additionally provided with liquid filtering on the probe tube outside the settling tank
Device (17).
8. device as described in claim 1, which is characterized in that the gas pipeline of crossing is additionally provided with air filter (31).
9. device as described in claim 1, which is characterized in that the feed pipe and discharge nozzle is equipped with valve (18).
10. device as described in claim 1, which is characterized in that the settling tank is additionally provided with heater.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821921339.5U CN209193857U (en) | 2018-11-21 | 2018-11-21 | A kind of albumen precipitation supernatant separation device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821921339.5U CN209193857U (en) | 2018-11-21 | 2018-11-21 | A kind of albumen precipitation supernatant separation device |
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| Publication Number | Publication Date |
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| CN209193857U true CN209193857U (en) | 2019-08-02 |
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ID=67425235
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| Application Number | Title | Priority Date | Filing Date |
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| CN201821921339.5U Active CN209193857U (en) | 2018-11-21 | 2018-11-21 | A kind of albumen precipitation supernatant separation device |
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| CN (1) | CN209193857U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111248335A (en) * | 2019-12-31 | 2020-06-09 | 宁夏佳立马铃薯产业有限公司 | Potato wet protein processing production line and method |
-
2018
- 2018-11-21 CN CN201821921339.5U patent/CN209193857U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111248335A (en) * | 2019-12-31 | 2020-06-09 | 宁夏佳立马铃薯产业有限公司 | Potato wet protein processing production line and method |
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