CN209172278U - A kind of full optics of the eye coherence tomography device based on slit-lamp platform - Google Patents
A kind of full optics of the eye coherence tomography device based on slit-lamp platform Download PDFInfo
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- CN209172278U CN209172278U CN201821508269.0U CN201821508269U CN209172278U CN 209172278 U CN209172278 U CN 209172278U CN 201821508269 U CN201821508269 U CN 201821508269U CN 209172278 U CN209172278 U CN 209172278U
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Abstract
The utility model discloses a kind of full optics of the eye coherence tomography device based on slit-lamp platform, including the OCT image system being arranged on slit-lamp platform and for the computer of signal processing, the OCT image system includes light source, to scan the sample arm of eyeball and generate the reference arm of interference light with sample arm, the sample arm and reference arm receive the light that light source issues, the reference arm includes lens barrel and the lens group that is arranged in lens barrel, the lens group includes one-dimensional galvanometer system and changeable at least four groups of plane mirrors, at least four groups of plane mirrors are different at a distance from one-dimensional galvanometer system.The device adjusts the depth of focus by switching different reflection microscope groups, and cooperation carries image processing software on computers and splices enhancing to multiple image, and then can be realized three-dimensional imaging of the single pass simultaneously to anterior chamber of eye and posterior segment on the apparatus.
Description
Technical field
The utility model belongs to optical imaging field, and in particular to a kind of full optics of the eye based on slit-lamp platform is relevant disconnected
Layer imaging device.
Background technique
The World Health Organization (WHO) statistics shows, in recent years ophthalmology disease have become after tumour, cardiovascular disease it
The third position disease of human health and life quality is endangered afterwards.China is the blind in the world and most state of impaired vision patient populations
Family, impaired vision seriously affects the eye Health and Living quality of the people, be related to the people's livelihood great public health problem and
Social concern.
Eyeball is made of the optical texture of precise structure and Microvasculature.It is rapid with ophthalmology imaging technique in recent years
Development, relevant scanning (Optical Coherence Tomography, OCT) this contactless, Noninvasive of optical fault
Novel ophthalmology diagnostic techniques appearance and development, provide important information, form for the diagnosing and treating of ophthalmology disease
It learns measurement function to be applied in the rigorous analysis of tear film, epithelium, anterior chamber, crystalline lens and retinal function, changes ophthalmology
Existing Diagnosis-treat Model, the milestone formula achievement of ophthalmology of being known as diagnostic techniques.
Expand the key technical problem that OCT scan depth is always OCT area research.With the full eye imaging of ultrahigh resolution
OCT can provide the diagnostic message in wider scope preferably to the image microstructures of tissue, greatly push to fundus oculi disease
The understanding and early diagnosis of pathology.However, the commercially use OCT functions of the equipments of eye examination at present are more single, what is had can only
The eyeball tissues such as the cornea for anterior chamber of eye, what is had can only be imaged for institutional frameworks such as posterior segment retinas.Although there are one
The disadvantages of a little to incorporate the technical solution of anterior chamber of eye, back segment imaging, but there is structure is complicated, inconvenient, lack one kind
It gathers with certain inspection comfort level, simple and fast, structure section, easy to operate imaging scheme.
Patent document CN201180001796.7 discloses a kind of realization back segment imaging device at the moment.By using reflecting mirror
Switch two sets optical paths mode, by OCT system scan arm sending light be converted into respectively anterior chamber of eye imaging probe and posterior segment at
As probe both can be carried out refraction compensation and remained that blinkpunkt is clear although this mode can be directed to the people of different eyesights.But
Aplanatic Surface can be only positioned at cornea or retina level when being due to imaging, only being capable of diagonal film, retinal structure focusing
Imaging, and increased imaging probe device keeps system structure complicated after OCT scan galvanometer system, the laser of light source sending is through popping one's head in
Polygonal mirror in device will cause system optical power attenuation, influence the image quality of OCT system.
Patent document CN201410243150.5 disclose one kind can be to full cornea, crystalline body front surface, crystalline lens after
The OCT device that surface and retinal structure are imaged.By using increase anterior ocular segment image-forming module and oculi posterior segment after scan arm
Image-forming module, the program can be respectively to eyeball different depth position scanning imageries.But since the program refers to arm lengths not
It is adjustable, therefore increases the light path regulating mechanism of design structure complexity, optical path length is caused to increase and reflecting mirror number in optical path
It measures more, will cause the optical power attenuation of system, influence image quality.
Utility model content
The main purpose of the utility model is to provide a kind of full optics of the eye coherence tomography based on slit-lamp platform
Device, can be automatically performed on the apparatus to patient's anterior chamber of eye and posterior segment cornea, Fang Jiao, crystal, retina high-resolution
The imaging of rate super large range.
To achieve the above objectives, a kind of the technical solution adopted in the utility model are as follows: full eye based on slit-lamp platform
Coherence tomography device is learned, including the OCT image system that is arranged on slit-lamp platform and for the computer of signal processing,
The OCT image system include light source, the sample arm to scan eyeball and with sample arm generate interference light reference arm, it is described
Sample arm and reference arm receive the light that light source issues, and the reference arm includes lens barrel and the lens group that is arranged in lens barrel, special
Sign is that the lens group includes one-dimensional galvanometer system and changeable at least four groups of plane mirrors, and described at least four groups flat
Face reflecting mirror is different at a distance from one-dimensional galvanometer system.
Preferably, the reference arm further includes before each plane mirror is arranged for adjusting focus first thoroughly
Mirror.
Preferably, the sample arm include 2-D vibration mirror system to scan eyeball and setting 2-D vibration mirror system with
It is in the heat reflection lens of 45 degree of angles installation between eyeball and with light beam.
Preferably, the sample arm further includes being arranged between heat reflection lens and eyeball and dismountable ophthalmoscope.
Preferably, the sample arm further includes the fixation system of aid imaging, and the fixation system includes to display target
Target target display screen and to obtain auxiliary positioning camera of the eyeball relative to the real time position of slit-lamp platform, the target
Display screen and auxiliary positioning camera are connected with computer.
It preferably, further include the spectrometer that Fourier transformation processing is carried out to the interference light that sample arm and reference arm generate.
Compared with prior art, the utility model has the following beneficial effects:
1) the utility model imaging system is controlled by computer, is automatically switched lens group and is adjusted optical path, makes imaging system
Anterior chamber of eye, middle section, back segment different location are focused, realizes and the very long range of full eye is imaged；
2) imaging method of the utility model design, by overlapping region as datum mark, using software superposition, splicing one
It is secondary to scan several pictures got, picture quality can be enhanced, and expand single pass areas imaging；
3) it by using the one-dimensional galvanometer of computer control as optical path auto-switch component, and then can realize automatically pair
The eyeball tissue of different depth is scanned.
Detailed description of the invention
Fig. 1 is a kind of image-forming principle of the full optics of the eye coherence tomography device based on slit-lamp platform of the utility model
Figure
Fig. 2 is a kind of optical path switching of full optics of the eye coherence tomography device based on slit-lamp platform of the utility model
Plant system drawing
Fig. 3 is a kind of full ophthalmic optical coherence fault imaging device optical path switching based on slit-lamp platform of the utility model
Image scanning range schematic diagram
Specific embodiment
It is described below for disclosing the utility model so that those skilled in the art can be realized the utility model.It retouches below
Preferred embodiment in stating is only used as illustrating, it may occur to persons skilled in the art that other obvious modifications.
As shown in Figure 1, a kind of full optics of the eye coherence tomography device based on slit-lamp platform, the imaging device packet
It includes the light source 1 that can emit specific wavelength laser, fiber coupling device 2, reference arm, sample arm, spectrometer and carries out image point
The computer of analysis.The light source 1 is connect by optical fiber with fiber coupling device 2, and the reference arm and sample arm pass through light respectively
Fibre is connect with fiber coupling device 2, and the light inlet of the spectrometer is connect by optical fiber with fiber coupling device 2, the spectrum
The signal output end of instrument is connect by high speed linear array CMOS camera 7 with computer.Wherein, spectrometer, high speed linear array CMOS camera 4
It is all made of the prior art.
The reference arm includes lens barrel and the lens group that is threadedly coupled with lens barrel, is provided in the light inlet of lens barrel to protect
The collimating mirror L1 and the adjustable slit 3 to adjust incident aperture and incident flux for holding beam collimation, the lens group can
Light from adjustable slit 3 is focused and is reflected, specifically, the lens group includes the lens L2 to focus light beam
And plane mirror M, the lens L2 to reflect light beam are convex lens, specifically, lens L2 and plane mirror M
Specification all use the prior art, and will not be described here in detail.
As depicted in figs. 1 and 2, the lens group further includes the one-dimensional vibration being arranged between lens L2 and plane mirror M
Mirror system G1, the plane mirror M have multiple, preferably four, respectively M1, M2, M3 and M4, different plane reflections
Distance of the mirror M apart from one-dimensional galvanometer system G1 is different, specifically, plane mirror M1 |, M2, M3, M4 be apart from one-dimensional galvanometer system
The distance of G1 gradually increases, and can be projected light beams upon on different plane mirror M by rotating one-dimensional galvanometer system G1.
The lens group further includes being arranged between each plane mirror and one-dimensional galvanometer system G1 to be used for light beam
Lens L11, L12, L13 and the L14 further focused.The specification of described lens L11, L12, L13, L14 use the prior art,
And will not be described here in detail.
The one-dimensional galvanometer system G1 can be controlled by computer, and Computer signal is transmitted to galvanometer controller 4, control
2-D vibration mirror G1 processed is rotated according to specific direction, angular dimension, optical path is switched to specific position and then can will be in optical path
Light beam project on the plane mirror M of needs.Plane mirror M1, M2, M3, M4 with respect to galvanometer G1 when being closer,
The system depth of focus is shallower, distance farther out when the depth of focus it is deeper.
The sample arm include 2-D vibration mirror system G2 and setting 2-D vibration mirror system G2 and sample human eye 13 it
Between the heat reflection lens 12 in 45 degree of setting angles, the heat reflection lens 12 can either by light a part reflect, again
Another part of light can be projected.The 2-D vibration mirror system G2 and heat reflection lens 12 are all made of the prior art, herein not
It is described in detail again.
The 2-D vibration mirror system G2 is equally controlled by computer 8, the galvanometer controller 5 of 2-D vibration mirror system G2 with
Computer 8, the 2-D vibration mirror system G2 after receiving computer and issuing and be transmitted to the signal of galvanometer controller 5, according to
Specific direction, angle rotation, by rotation, light can same depth to eyeball different location planar sweep
It retouches.
The sample arm further includes multiple lens L4, L6 and ophthalmoscope L5, be can be realized pair by lens L4, L5, L6
The adjusting of optical path, described lens L4, L5, L6 are convex lens, can be to light beam by carrying out position adjustment along beam direction
Focus condition be finely adjusted.The ophthalmoscope L5 is arranged between hot mirror 12 and eyeball 13, and specifically, ophthalmoscope L5 is logical
Cross the suitable position for being magnetically attached to slit-lamp platform.The lens L4 is arranged in 2-D vibration mirror system G2 and heat reflection lens 12
Between.The lens L6 is arranged opposite heat reflection lens 12 and is located at the side opposite with lens L5.Described lens L4, L5, L6's
Specification uses the prior art, and and will not be described here in detail.
The laser aligner L3 to guarantee laser alignment, the laser quasi are additionally provided in the light inlet of the sample arm
Straight device L3 uses the prior art, and and will not be described here in detail.
The spectrometer includes collimating mirror L8, grating 6 and lens L7, spectrometer and collimating mirror L8, grating 6 and lens L7
It is all made of the prior art, and will not be described here in detail.What the light and sample arm that reference arm returns returned has sample tissue information (eyeball
Information) light interfere after enter spectrometer, the interference light with sample tissue information after interfering is in spectrum
It carries out passing through high speed linear array CMOS camera 7 and entering after frequency domain Fourier transformation in instrument carrying out processing imaging in computer 8.
The sample arm further includes the fixation system of aid imaging, and the fixation system is swept to the eyeball to patient
When retouching imaging, detected person's sight is fixed, eliminates influence of the eyeball movement to imaging process.
The fixation system includes to display target target target display screen 9 and auxiliary positioning camera 11, and the target is aobvious
Display screen 9 and auxiliary positioning camera 11 are connect with Computer signal, the display of the target display screen 9 by computer control,
I.e. computer can control target in the display position of target display screen 9, when scanning eyeball, control target by computer and exist
Position on target display screen 9 makes detected person's eyeball realize fixation and watching target attentively by adjusting target position, into
And to the specific position scanning imagery of eyeball.When adjusting target position, the position of eyeball can pass through heat reflection lens 12, lens L6
Auxiliary positioning camera 11 is entered, the eyeball position that auxiliary positioning camera 11 obtains can be shown in a computer, can pass through tune
The position that target is shown in whole target display screen 9, the eyeball of such detected person can follow target mobile, and then can be realized pair
The detection of eyeball specific position.In order to make auxiliary positioning camera 11 that can enable eyeball again while obtaining eyeball position
It observes the target in target display screen 9, is provided with light beam splitter 10 before target display screen 9 and lens L6, passes through light
Line beam splitter 10, eyeball are able to observe that the target in target display screen 9, and it is opposite that auxiliary positioning camera 11 can also obtain eyeball
In the position of slit-lamp platform.
When system is run, the laser of light source 1 is divided into two bundles by fiber coupling device 2, has respectively entered reference arm and sample
Product arm, the laser for entering reference arm return in fiber coupling device 2 by plane mirror M, and laser enters sample arm
Later, 2-D vibration mirror system G2 is scanned eyeball and returns to the result of scanning in fiber coupling device 2, by reference
The light that arm and sample arm return is interfered in fiber coupling device 2, and individual reflection can be enhanced by interference, weaken scattering
The radiation of light enhances the sample tissue information of different depth, that is to say, that when by adjusting the one-dimensional galvanometer system in reference arm
When system G1 reflects different plane mirror M to light beam, since the light beam depth of different plane mirror M is different,
In this way when the light beam of reference arm reflection and the light beam of sample arm reflection interfere, in the light beam and reference arm in sample arm when
The sample tissue information that plane mirror used in preceding corresponds to depth is enhanced, and other depth obtain sample tissue information quilt
The certain depth that decrease, i.e. each plane mirror correspond to eyeball, and then by program adjust automatically reference arm
Currently used plane mirror M can detect the sample tissue of different depth.Interference light is then into light
Spectrometer carries out frequency domain Fourier transformation, and passing through high speed linear array CMOS camera 7 is transmitted to computer 8 later, passes through the place of computer 8
Reason is final to obtain the 3-D image comprising eyeball structure information.
Since in this embodiment, therefore tool can obtain the image of four kinds of different depths there are four plane mirror.It is right
The image of these four different depths has partial region overlapping, in a computer using overlapping region as datum mark to different depth
Image be overlapped, splice and then obtain the faultage image of eyeball.Above-mentioned partial region is overlapped, to different depth
When eyeball tissue is scanned, overlapping region can be scanned artificially in order to be folded by point on the basis of the region that these are overlapped
Add.
As shown in Figures 2 and 3, when device is to ocular imaging, every single sweep operation, one-dimensional galvanometer system G1 is according to computer 8
Program setting, rotated according to specific direction and angle, optical path successively switched to reflecting mirror M1, M2, M3, M4.Such as Fig. 2, phase
It answers, the laser signal scanning area that light source issues is covered to P1, P2, P3, P4, and computer controls galvanometer system G1, G2 circulation
Scanning, so that it may obtain a series of faultage images of eyeball corresponding position.
Basic principles, main features, and advantages of the present invention has been shown and described above.Current row
The technical staff of industry is described in above embodiments and description it should be appreciated that the present utility model is not limited to the above embodiments
Only the principles of the present invention, the utility model also has respectively on the premise of not departing from the spirit and scope of the utility model
Kind changes and improvements, these changes and improvements are both fallen in the range of claimed invention.The requires of the utility model
Protection scope defined by appended claims and its equivalent.
Claims (6)
1. a kind of full optics of the eye coherence tomography device based on slit-lamp platform, including being arranged on slit-lamp platform
OCT image system and computer for signal processing, the OCT image system includes light source, the sample to scan eyeball
Arm and the reference arm that interference light is generated with sample arm, the sample arm and reference arm receive the light that light source issues, the reference arm
Including lens barrel and the lens group being arranged in lens barrel, which is characterized in that the lens group includes one-dimensional galvanometer system and can be switched
At least four groups of plane mirrors, at least four groups of plane mirrors are different at a distance from one-dimensional galvanometer system.
2. a kind of full optics of the eye coherence tomography device based on slit-lamp platform according to claim 1, feature
It is, the reference arm further includes before each plane mirror is arranged for adjusting the first lens focused.
3. a kind of full optics of the eye coherence tomography device based on slit-lamp platform according to claim 1 or 2, special
Sign is, the sample arm includes 2-D vibration mirror system to scan eyeball and is arranged between 2-D vibration mirror system and eyeball
And with light beam in the heat reflection lens of 45 degree of angles installation.
4. a kind of full optics of the eye coherence tomography device based on slit-lamp platform according to claim 3, feature
It is, the sample arm further includes being arranged between heat reflection lens and eyeball and dismountable ophthalmoscope.
5. a kind of full optics of the eye coherence tomography device based on slit-lamp platform according to claim 3, feature
It is, the sample arm further includes the fixation system of aid imaging, and the fixation system includes aobvious to display target target target
Display screen and to obtain auxiliary positioning camera of the eyeball relative to the real time position of slit-lamp platform, the target display screen and auxiliary
Positioning camera is helped to be connected with computer.
6. a kind of full optics of the eye coherence tomography device based on slit-lamp platform according to claim 3, feature
It is, further includes the spectrometer for carrying out Fourier transformation processing to the interference light that sample arm and reference arm generate.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109008942A (en) * | 2018-09-15 | 2018-12-18 | 中山大学中山眼科中心 | A kind of full optics of the eye coherence tomography device and imaging method based on slit-lamp platform |
| CN113729615A (en) * | 2021-10-12 | 2021-12-03 | 中山大学中山眼科中心 | Optical coherence tomography device with a hand-held probe |
-
2018
- 2018-09-15 CN CN201821508269.0U patent/CN209172278U/en active Active
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109008942A (en) * | 2018-09-15 | 2018-12-18 | 中山大学中山眼科中心 | A kind of full optics of the eye coherence tomography device and imaging method based on slit-lamp platform |
| CN113729615A (en) * | 2021-10-12 | 2021-12-03 | 中山大学中山眼科中心 | Optical coherence tomography device with a hand-held probe |
| CN113729615B (en) * | 2021-10-12 | 2023-01-13 | 中山大学中山眼科中心 | Optical coherence tomography device with a hand-held probe |
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| TR01 | Transfer of patent right |
Effective date of registration: 20210819 Address after: 510000 No. 7, Jinsui Road, Tianhe District, Guangzhou City, Guangdong Province Patentee after: ZHONGSHAN OPHTHALMIC CENTER, SUN YAT-SEN University Patentee after: SUN YAT-SEN University Address before: 510000 1603, building 3, Zhongshan ophthalmology center, Sun Yat sen University, No. 54, Xianlie South Road, Yuexiu District, Guangzhou, Guangdong Province Patentee before: ZHONGSHAN OPHTHALMIC CENTER, SUN YAT-SEN University |
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Effective date of registration: 20230518 Address after: Room 406, No. 1, Yichuang Street, Huangpu District (Zhongxin Guangzhou Knowledge City), Guangzhou City, Guangdong Province, 510000 Patentee after: Meishi Optical Technology (Guangdong) Co.,Ltd. Address before: 510000 No. 7, Jinsui Road, Tianhe District, Guangzhou City, Guangdong Province Patentee before: ZHONGSHAN OPHTHALMIC CENTER, SUN YAT-SEN University Patentee before: SUN YAT-SEN University |