CN209108380U - A kind of medicinal balloon catheter and balloon-system - Google Patents
A kind of medicinal balloon catheter and balloon-system Download PDFInfo
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- CN209108380U CN209108380U CN201821243355.3U CN201821243355U CN209108380U CN 209108380 U CN209108380 U CN 209108380U CN 201821243355 U CN201821243355 U CN 201821243355U CN 209108380 U CN209108380 U CN 209108380U
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- sacculus
- avulsion
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Abstract
The utility model provides a kind of medicinal balloon catheter and balloon-system, is related to the field of medical instrument technology.The medicinal balloon catheter includes medicine ball catheter body and protection sheath；The protection sheath is wrapped on the outer surface of the medicine ball catheter body；The protection sheath can be deviate from from the medicine ball catheter body.The balloon-system includes said medicine foley's tube.The utility model solves in medicinal balloon catheter existing in the prior art that Drug bioavailability is low, the technical problem of therapeutic effect difference.
Description
Technical field
The utility model relates to the field of medical instrument technology, more particularly, to a kind of medicinal balloon catheter and balloon-system.
Background technique
The disease incidence of hemadostewnosis or occlusion that atherosclerosis causes increases year by year, even if in bracket for eluting medicament
(DES) commonly used epoch, the lesion vessels or in-stent restenosis that long-term postoperative causes by endometrial hyperplasia cause the state of an illness anti-
Multiple is always a great problem for perplexing clinician.In recent years, the appearance of medicine-coated balloon (DCB) is to prevent lumen restenosis
Provide a kind for the treatment of method of relative efficiency.It is coated with anti-proliferative drug taxol identical with DES in sacculus outer surface
(Paclitaxel), drug effect can be retained to the quick absorption of drug and for a long time by vascular tissue, it is comparable with DES to reach
The effect of anti-endometrial hyperplasia, while avoiding the complication of DES initiation (endometrial hyperplasia in such as thrombus in stents, bracket, bracket are disconnected
It splits).
During design medicine coating foley's tube, the characteristic of foley's tube itself is not only considered, it is closer
In conjunction with application of the drug coated balloon catheter in actual operation.It is up to medicinal balloon catheter so that the elder generation listed domestic at present is auspicious
Example, after the connector of medicinal balloon catheter is accessed blood vessel, medicinal balloon catheter is entered by the position of connector, in guide wire
On the position for reaching target lesion under guide function, then dilating sacculus, so that the drug release on sacculus, and infiltrate and arrive vascular wall
It is interior.In said medicine transmission process, after medicinal balloon catheter is entered by connector, since a part of medicine can be lost in the presence of friction
Object；During reaching target lesion position under the guide function of guide wire, a part of drug caused by also being washed away because of blood flow
It is lost；After balloon expandable, there are still losses for the drug in balloon surface, can finally be coated on the drug being utilized on vascular wall
And it is few, influence therapeutic effect.Accordingly, it is considered to the drug loss rate of the above process be arrived, in the manufacturing process of medicine-coated balloon
In, it has to increase sacculus drugloading rate.And accompanying problem is that, mistake drug is washed away by blood flow on sacculus remains in body
It is interior, undesirably increase the risk of adverse drug reaction.Therefore, medicine-coated balloon using maximum difficult point is exactly at present
The sacculus for carrying upper certain drug how is set to reduce loss to the greatest extent during conveying, to reach higher Drug bioavailability
And therapeutic effect reduces the residual of drug in vivo as far as possible simultaneously.
Based on this, the utility model provides a kind of medicinal balloon catheter and balloon-system is asked with solving above-mentioned technology
Topic.
Utility model content
The purpose of this utility model is to provide a kind of medicinal balloon catheters, to solve drug ball existing in the prior art
Drug bioavailability is low in ductus bursae, the technical problem of therapeutic effect difference.
The purpose of this utility model, which also resides in, provides a kind of balloon-system, and the balloon-system includes said medicine sacculus
Conduit, the technical problem of therapeutic effect difference low for solving Drug bioavailability in medicinal balloon catheter.
Based on above-mentioned first purpose, the utility model provides a kind of medicinal balloon catheter, including medicine ball catheter body and
Protect sheath；
The protection sheath is wrapped on the outer surface of the medicine ball catheter body；The protection sheath can be led from the medicine ball
Deviate from tube body.
Optionally, said medicine foley's tube further includes avulsion structure；
The avulsion structure is for coming out the protection sheath from avulsion in the medicine ball catheter body.
Optionally, said medicine foley's tube, the avulsion structure are the length direction setting along the protection sheath
First avulsion line.
Optionally, said medicine foley's tube, the medicine ball catheter body include catheter shaft and are arranged on catheter shaft
Inflatable sacculus；
The protection sheath includes the first protection portion and the second protection portion；First protection portion wraps up the appearance of the sacculus
Face；Second protection portion wraps up the outer surface of the catheter shaft Yu the sacculus end link position.
Optionally, said medicine foley's tube is provided with a plurality of second avulsion line in first protection portion；
The every second avulsion line is arranged each along the length direction of the protection sheath；The a plurality of second avulsion line edge
First protection portion circumferentially.
Optionally, said medicine foley's tube, one end of second protection portion is connect with first protection portion, another
End is fixedly connected with the catheter shaft.
Optionally, said medicine foley's tube is provided with scale on the protection sheath.
Optionally, said medicine foley's tube, it is described protection sheath outer surface on be provided with hydrophilic coating.
Optionally, said medicine foley's tube, the protection sheath are degradable film.
Based on above-mentioned second purpose, the utility model provides a kind of balloon-system, and the balloon-system includes described
Medicinal balloon catheter.
The medicinal balloon catheter provided by the utility model, including medicine ball catheter body and protection sheath；The protection sheath
It is wrapped on the outer surface of the medicine ball catheter body；The protection sheath can be deviate from from the medicine ball catheter body.This reality
It is wrapped up with novel medicine ball catheter body by protection sheath, after the sacculus in medicine ball catheter body reaches target lesion position, is first torn
Lower protection sheath exposes the sacculus in medicine ball catheter body, gives inflated, the drug release that will be attached on sacculus immediately after
Into blood vessel.Continue to tear within the waiting period of medicine ball expansion and protects sheath until all withdrawing from external.Protection sheath effectively prevent ball
The drug wastage that drug on capsule occurs during reaching target lesion position when entering blood vessel and by guiding tube, improves medicine
The bioavailability of object.
The medicinal balloon device provided by the utility model, includes said medicine foley's tube, therefore is had above-mentioned
All advantages of medicinal balloon catheter.
Based on this, the utility model has the advantages that improve the bioavailability of drug compared with original technology.
Detailed description of the invention
It, below will be right in order to illustrate more clearly of specific embodiment of the present invention or technical solution in the prior art
Specific embodiment or attached drawing needed to be used in the description of the prior art are briefly described, it should be apparent that, it is described below
In attached drawing be that some embodiments of the utility model are not paying creativeness for those of ordinary skill in the art
Under the premise of labour, it is also possible to obtain other drawings based on these drawings.
Fig. 1 is the structural schematic diagram of the first state of medicinal balloon catheter provided by the embodiment of the utility model；
Fig. 2 is the cross-sectional view of Fig. 1；
Fig. 3 is the structural schematic diagram of second of state of medicinal balloon catheter provided by the embodiment of the utility model；
Fig. 4 is to protect a kind of package mode of sheath in medicinal balloon catheter provided by the embodiment of the utility model；
Fig. 5 is the structural schematic diagram that sheath is protected in medicinal balloon catheter provided by the embodiment of the utility model.
Icon: 100- protects sheath；101- the first avulsion line；The first protection portion of 102-；The second protection portion of 103-；104- second
Avulsion line；200- medicine ball catheter body；201- catheter shaft；202- sacculus.
Specific embodiment
The technical solution of the utility model is clearly and completely described below in conjunction with attached drawing, it is clear that described
Embodiment is the utility model a part of the embodiment, instead of all the embodiments.Based on the embodiments of the present invention, originally
Field those of ordinary skill every other embodiment obtained without making creative work belongs to practical
Novel protected range.
It is in the description of the present invention, it should be noted that term " center ", "upper", "lower", "left", "right", " perpendicular
Directly ", the orientation or positional relationship of the instructions such as "horizontal", "inner", "outside" is to be based on the orientation or positional relationship shown in the drawings, and is only
For ease of description the utility model and simplify description, rather than the device or element of indication or suggestion meaning must have it is specific
Orientation, be constructed and operated in a specific orientation, therefore should not be understood as limiting the present invention.In addition, term " the
One ", " second ", " third " are used for descriptive purposes only and cannot be understood as indicating or suggesting relative importance.
In the description of the present invention, it should be noted that unless otherwise clearly defined and limited, term " is pacified
Dress ", " connected ", " connection " shall be understood in a broad sense, for example, it may be being fixedly connected, may be a detachable connection, or integrally
Connection；It can be mechanical connection, be also possible to be electrically connected；Can be directly connected, can also indirectly connected through an intermediary,
It can be the connection inside two elements.For the ordinary skill in the art, above-mentioned art can be understood with concrete condition
The concrete meaning of language in the present invention.
Embodiment one
Fig. 1 is the structural schematic diagram of the first state of medicinal balloon catheter provided by the embodiment of the utility model；Fig. 2 is figure
1 cross-sectional view；Fig. 3 is the structural schematic diagram of second of state of medicinal balloon catheter provided by the embodiment of the utility model.
A kind of medicinal balloon catheter is provided in the present embodiment, and the medicinal balloon catheter includes medicine ball catheter body
200 and protection sheath 100；
The protection sheath 100 is wrapped on the outer surface of the medicine ball catheter body 200；The protection sheath 100 can be from
Deviate from the medicine ball catheter body 200.
The medicinal balloon catheter provided by the utility model, medicine ball catheter body 200 are wrapped up by protection sheath 100, medicine
After sacculus 202 in ball catheter body 200 reaches target lesion position, first tears in one end far from sacculus and extract protection sheath
100, to expose the sacculus 202 in medicine ball catheter body 200, then inflated to sacculus 202, to will be attached on sacculus 202
Drug release is into blood vessel.Within the waiting time of inflated, continue to tear and pull protection sheath until withdrawing from completely external.
During protection sheath 100 effectively prevent the drug on sacculus 202 to reach target lesion position when entering blood vessel and by guiding tube
The drug wastage of generation improves the bioavailability of drug.
Based on this, the utility model has the advantages that improve the bioavailability of drug compared with original technology.
It further include avulsion structure in the optinal plan of the present embodiment；
The avulsion structure is for coming out the protection sheath 100 from avulsion in the medicine ball catheter body 200.
Sacculus 202 on medicinal balloon catheter needs to expand and discharges drug when reaching target lesion position, therefore, protects sheath
100 need to remove before sacculus 202 is expanded or sacculus 202 expand tension enable to protection sheath 100 rupture, will
Drug on sacculus 202 is successfully discharged into target lesion position, reduces drug wastage, improves therapeutic effect.
In the above-mentioned technical solutions, further, the avulsion structure is to set along the length direction of the protection sheath 100
The the first avulsion line 101 set.
As shown in Figure 1, Figure 2 and Figure 3, protection sheath 100 is wrapped up by wherein one end of medicine ball catheter body 200 to the other end,
Therefore, the first avulsion line 101 also extends to the other end by wherein one end of medicine ball catheter body 200.The tool of first avulsion line 101
Body structure is multiple spaced long holes, and the center line of each long hole length direction constitutes the center of the first avulsion line 101
Line.First avulsion line 101 makes that the bonding strength of sheath 100 in the position is protected to substantially reduce, when removing protection sheath 100, slightly
The structure of the first avulsion line 101 just can be destroyed to the power of a tear-off, to expose sacculus 202, sheath will be protected by continuing tear-off
100 take out from blood vessel.
In the above-mentioned technical solutions, further, scale is provided on the protection sheath 100.
Specifically, the scale is mark point corresponding with length of balloon, effect is to determine that protection 100 head end of sheath is dropped back
Length, i.e., when protection sheath is torn to mark point, the protection sheath for representing package balloon position is withdrawn from completely, and sacculus is fully exposed to body
It is interior, it can be inflated immediately.
In the above-mentioned technical solutions, further, the outer surface of the protection sheath 100 is hydrophilic coating.
Medicinal balloon catheter since entering blood vessel until the position for reaching target lesion needs very long a certain distance, and drug
The movement of foley's tube in the blood vessel inevitably can generate friction with vascular wall, bring resistance to the advance of medicinal balloon catheter, very
Vascular wall can extremely be damaged.Therefore, the present embodiment provides medicinal balloon catheters is provided with hydrophilic coating on the surface of protection sheath 100,
It can be effectively reduced the resistance of medicinal balloon catheter advance, protection vascular wall is injury-free.
Embodiment two
Fig. 4 is to protect a kind of package mode of sheath 100 in medicinal balloon catheter provided by the embodiment of the utility model；Fig. 5
For the structural schematic diagram for protecting sheath 100 in medicinal balloon catheter provided by the embodiment of the utility model.
As shown in figure 4, providing a kind of medicinal balloon catheter in the present embodiment, the medicinal balloon catheter includes medicine ball
Catheter body 200 and protection sheath 100；
The protection sheath 100 is wrapped on the outer surface of the medicine ball catheter body 200；The protection sheath 100 can be from
Deviate from the medicine ball catheter body 200.
The medicinal balloon catheter provided by the utility model, medicine ball catheter body 200 are wrapped up by protection sheath 100, medicine
It after sacculus 202 in ball catheter body 200 reaches target lesion position, first tears and protects sheath 100, expose medicine ball catheter body 200
On sacculus 202, then to sacculus 202 inflate, the drug release on sacculus 202 will be attached into blood vessel.Protection sheath 100 has
The drug stream that effect prevents the drug on sacculus 202 from occurring during reaching target lesion position when entering blood vessel and by guiding tube
It loses, improves the bioavailability of drug.
Based on this, the utility model has the advantages that improve the bioavailability of drug compared with original technology.
As shown in figure 5, further including avulsion structure in the optinal plan of the present embodiment；
The avulsion structure is for coming out the protection sheath 100 from avulsion in the medicine ball catheter body 200.
Sacculus 202 on medicinal balloon catheter needs to expand and discharges drug when reaching target lesion position, therefore, protects sheath
100 need to remove before sacculus 202 is expanded or sacculus 202 expand tension enable to protection sheath 100 rupture, will
Drug on sacculus 202 is successfully discharged into target lesion position, reduces drug wastage, improves therapeutic effect.
In the above-mentioned technical solutions, further, the medicine ball catheter body 200 includes that catheter shaft 201 and setting are being led
Inflatable sacculus 202 on pipe axis 201；
The protection sheath 100 includes the first protection portion 102 and the second protection portion 103；First protection portion 102 wraps up institute
State the outer surface of medicinal balloon 202；Second protection portion 103 is wrapped up the catheter shaft 201 and is connect with 202 end of sacculus
The outer surface of position.
Mainly protect sheath 100 main on sacculus 202, in the present embodiment in the medicament-carried position of medicine ball catheter body 200
Wrap up sacculus 202, including the first protection portion 102 and the second protection portion 103, wherein the first protection portion 102 wraps up sacculus 202
Outer surface, the outer surface that the second protection portion 103 package catheter shaft 201 is connect with 202 end of sacculus, to prevent drug from sacculus
202 end is lost, and the specific structure is shown in FIG. 3.
In the above-mentioned technical solutions, further, one end of second protection portion 103 and first protection portion 102
Connection, the other end are fixedly connected with the catheter shaft 201.
In the above-mentioned technical solutions, further, a plurality of second avulsion line 104 is provided in first protection portion 102；
The every second avulsion line 104 is arranged each along the length direction of the protection sheath 100；A plurality of described second tears
Off-line 104 along first protection portion 102 circumferentially.
In this example, the first protection portion 102 is an integral structure with the second protection portion 103, and the second protection portion 103 is far from sacculus
202 one end is fixedly connected with catheter shaft 201.Since the tool of sacculus 202 is there are two end, the second guarantor is provided on two ends
Shield portion 103, therefore the one end of the second protection portion 103 far from sacculus 202 is fixedly connected with catheter shaft 201 and two kinds of situations occurs: the
One is only one one end of the second protection portion 103 far from sacculus 202 in two the second protection portion 103 and catheter shaft 201 are solid
Fixed connection；Second is that two second one end of protection portion 103 far from sacculus 202 are fixedly connected with catheter shaft 201.
For the structure of the first protection sheath 100, avulsion structure can be using the knot of the first avulsion line 101 in embodiment one
Structure, protection sheath 100 reach dilating sacculus 202 behind target lesion position, expanded by sacculus 202 without removing before expansion
Power destroys the first avulsion line 101, exposes sacculus 202 to realize and releases medicine in blood vessel.Since protection sheath 100 is separate
One end of sacculus 202 is fixed on catheter shaft 201, and the other end will not be directly entered in blood vessel after destroying, and finally follows conduit
Axis 201 is withdrawn from.It is emphasized that in the present solution, the quantity of the first avulsion line 101 can be one, it can also be to be a plurality of, setting
The bonding strength of tension and the first avulsion line 101 expanded according to sacculus 202 of quantity determine.
The structure of sheath 100 is protected for second, the second avulsion line is arranged on the outer surface of protection sheath 100 in the present embodiment
104.The quantity of second avulsion line 104 at least two: first length directions along the protection sheath 100 are arranged；Second
Item is arranged along the circumferential of protection sheath 100.When the second avulsion line 104 is a plurality of, a week along protection sheath 100 is only needed to have
To setting, remaining a plurality of second avulsion line 104 is arranged each along the length direction of the protection sheath 100.After sacculus 202 is expanded,
Tension will destroy each the second avulsion of item line 104, and catheter shaft due to two second one end of protection portion 103 far from sacculus 202
201 are fixedly connected, and protection sheath 100 will not be directly entered blood vessel after destroying, and finally catheter shaft 201 can be followed to withdraw from.
In the optinal plan of the present embodiment, the protection sheath 100 is degradation material.
Protection sheath 100, which follows conduit to withdraw from, there will still likely be the possibility that friction is generated with vascular wall, protect in the present embodiment
Sheath 100 can choose the medicative protective film of tool, which can degrade after being ruptured, avoid protection sheath 100 in blood vessel
Middle generation obstruction rubs with vascular wall, while can also make up the dose lost after sacculus 202 is expanded.
Embodiment three
This embodiment offers a kind of balloon-system, the balloon-system includes connector and embodiment one or implements
The medicinal balloon catheter in example two.
Connector is arranged on one of end of catheter shaft 201, and when use is fixed on the mobile road of medicinal balloon catheter
The start position of diameter.Since the balloon-system that this example provides includes the medicinal balloon catheter in embodiment one or embodiment two,
Therefore have the advantages that all of medicinal balloon catheter in embodiment one or embodiment two.
Finally, it should be noted that the above various embodiments is only to illustrate the technical solution of the utility model, rather than it is limited
System；Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should
Understand: it is still possible to modify the technical solutions described in the foregoing embodiments, or to some or all of
Technical characteristic is equivalently replaced；And these are modified or replaceed, it does not separate the essence of the corresponding technical solution, and this is practical new
The range of each embodiment technical solution of type.
Claims (10)
1. a kind of medicinal balloon catheter, which is characterized in that including medicine ball catheter body and protection sheath；
The protection sheath is wrapped on the outer surface of the medicine ball catheter body；The protection sheath can be from the medicine ball conduit sheet
Deviate from body.
2. medicinal balloon catheter according to claim 1, which is characterized in that further include avulsion structure；
The avulsion structure is for coming out the protection sheath from avulsion in the medicine ball catheter body.
3. medicinal balloon catheter according to claim 2, which is characterized in that the avulsion structure is along the protection sheath
Length direction setting the first avulsion line.
4. medicinal balloon catheter according to claim 2, which is characterized in that the medicine ball catheter body include catheter shaft and
Inflatable sacculus on catheter shaft is set；
The protection sheath includes the first protection portion and the second protection portion；First protection portion wraps up the outer surface of the sacculus；
Second protection portion wraps up the outer surface of the catheter shaft Yu the sacculus end link position.
5. medicinal balloon catheter according to claim 4, which is characterized in that be provided with a plurality of in first protection portion
Two avulsion lines；
The every second avulsion line is arranged each along the length direction of the protection sheath；The a plurality of second avulsion line is along institute
State the first protection portion circumferentially.
6. medicinal balloon catheter according to claim 5, which is characterized in that one end of second protection portion and described the
The connection of one protection portion, the other end are fixedly connected with the catheter shaft.
7. medicinal balloon catheter according to claim 1, which is characterized in that be provided with scale on the protection sheath.
8. medicinal balloon catheter according to claim 1, which is characterized in that be provided with parent on the outer surface of the protection sheath
Water coating.
9. medicinal balloon catheter according to claim 1, which is characterized in that the protection sheath is degradable film.
10. a kind of balloon-system, which is characterized in that the balloon-system includes such as the described in any item drugs of claim 1-9
Foley's tube.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821243355.3U CN209108380U (en) | 2018-08-01 | 2018-08-01 | A kind of medicinal balloon catheter and balloon-system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821243355.3U CN209108380U (en) | 2018-08-01 | 2018-08-01 | A kind of medicinal balloon catheter and balloon-system |
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| Publication Number | Publication Date |
|---|---|
| CN209108380U true CN209108380U (en) | 2019-07-16 |
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| CN201821243355.3U Active CN209108380U (en) | 2018-08-01 | 2018-08-01 | A kind of medicinal balloon catheter and balloon-system |
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| CN (1) | CN209108380U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109173016A (en) * | 2018-08-01 | 2019-01-11 | 中国医学科学院北京协和医院 | A kind of medicinal balloon catheter and balloon-system |
-
2018
- 2018-08-01 CN CN201821243355.3U patent/CN209108380U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109173016A (en) * | 2018-08-01 | 2019-01-11 | 中国医学科学院北京协和医院 | A kind of medicinal balloon catheter and balloon-system |
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