CN209107665U - Conscious mouse head fixer - Google Patents
Conscious mouse head fixer Download PDFInfo
- Publication number
- CN209107665U CN209107665U CN201821746677.XU CN201821746677U CN209107665U CN 209107665 U CN209107665 U CN 209107665U CN 201821746677 U CN201821746677 U CN 201821746677U CN 209107665 U CN209107665 U CN 209107665U
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- fixture block
- main body
- fixer
- cylinder
- adjustable column
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Abstract
The utility model discloses a kind of conscious mouse head fixers, including pedestal, fixer main body, station plate, adjustable column, first fixture block, second fixture block, fetter cylinder, titanium alloy circle, the fixer main body is fixedly mounted on the front end above pedestal, and station plate is provided with above fixer main body, station plate both ends, which symmetrically bolt, adjustable column, the adjustable column upper end is fixedly connected with the first fixture block by fastening bolt, and first is fixedly connected with the second fixture block by the first tightening knob above fixture block, the first fixture block and the second fixture block are combined into the collet for fixing titanium alloy circle simultaneously, the pedestal rear end is provided with constraint cylinder.The utility model can firmly fix the head of experiment mice, and accurately carry out flat cranium adjusting to mouse head angle.
Description
Technical field
The utility model relates to implement fixed device, specially a kind of conscious mouse to animal for medical treatment or experiment purpose
Head fixer.
Background technique
Two Photon Fluorescence has been applied to very universally in the research of Neurobiology, especially body function at
Picture, but between experimental animal and microscope, the animal fixing device of such as living imaging there are no producer's research and development and is provided,
Conscious mouse head fixer disclosed by the utility model has just filled up the market vacancy.
This instrument is also suitable for use in the record experiment of living body depth Electroencephalo, especially in sobering animal experiment, is solved
Naoliqing capsule problem in sobering animal depth Electroencephalo record, the unicellular electricity that can accurately record deep brain small nut group are living
It is dynamic, it can be used in combination with technological perfectionisms such as Tetrode, Optotrode and MEA.When carrying out sobering animal electrophysiological recording, tradition
Fixed device is the integrated positioning with ear bar and tooth bar, but the device cannot firmly fix the head of experiment mice, also not
Flat cranium adjusting accurately can be carried out to mouse head angle.
Utility model content
The utility model solve the technical issues of be to overcome defect of the existing technology, a kind of conscious mouse head is provided
Fixer.The present apparatus can be carried out accurately before and after AP(bregma) and ML(in meet before and after) angular adjustments of two axial directions, and
Each being adjusted axially range is both greater than 15 degree, in conjunction with reasonable experiment flow, the fixed electrophysiological recording of sobering animal head is allowed to have
Operability and precision well.
To achieve the above object, the utility model provides the following technical solutions: a kind of conscious mouse head fixer, including base
Seat, fixer main body, station plate, adjustable column, the first fixture block, the second fixture block, titanium alloy circle, the fixer main body are fixed
It is mounted on the front end above pedestal, and is provided with station plate above fixer main body, station plate both ends are symmetrical
Bolt has adjustable column, and the adjustable column upper end is fixedly connected with the first fixture block by fastening bolt, and passes through above the first fixture block
First tightening knob is fixedly connected with the second fixture block, while the first fixture block and the second fixture block are combined into for fixing titanium alloy circle
Collet.
Preferably, the pedestal rear end is provided with constraint cylinder, and fetters and be equipped with cylinder support below cylinder, cylinder support side
It is fixedly connected with support plate on pedestal, and is provided with strip groove among support plate, the cylinder support passes through the fixed peace of the second tightening knob
It fills on the supporting plate and can be moved up and down in strip groove.
Preferably, the constraint cylinder is wedge shape close to adjustable column one end.
Preferably, it is provided with the first adjusting knob on front side of the fixer main body, right side is provided with the second adjusting knob.
Preferably, the position on the fixer main body lateral surface and below the first adjusting knob and the second adjusting knob
It sets and indicates graduation mark respectively.
Compared with prior art, the utility model has the beneficial effects that the present apparatus can firmly fix experiment mice
Head, and flat cranium adjusting accurately is carried out to mouse head angle.
Detailed description of the invention
Fig. 1 is conscious mouse head fixer main view in an embodiment of the present invention；
Fig. 2 is conscious mouse head fixer top view in an embodiment of the present invention；
Fig. 3 is the support plate left view of conscious mouse head fixer in an embodiment of the present invention.
Figure label: 1- pedestal, 2- fixer main body, 3- station plate, the first adjusting knob of 4-, 5- second adjust rotation
Button, 6- adjustable column, the first fixture block of 7-, the second fixture block of 8-, 9- fastening bolt, the first tightening knob of 10-, 11- fetter cylinder, 12- titanium
Alloy ring, 13- support plate, 14- strip groove, the second tightening knob of 15-, 16- supports.
Specific embodiment
The following will be combined with the drawings in the embodiments of the present invention, carries out the technical scheme in the embodiment of the utility model
Clearly and completely describe, it is clear that the described embodiments are only a part of the embodiments of the utility model, rather than whole
Embodiment.Based on the embodiments of the present invention, those of ordinary skill in the art are without making creative work
Every other embodiment obtained, fall within the protection scope of the utility model.
As shown in Figure 1, the utility model provides a kind of technical solution: a kind of conscious mouse head fixer, including pedestal 1,
Fixer main body 2, station plate 3, adjustable column 6, the first fixture block 7, the second fixture block 8, constraint cylinder 11, titanium alloy circle 12, it is fixed
Instrument main body 2 is fixedly mounted on the front end of 1 top of pedestal, and station plate 3 is provided with above fixer main body 2, and station is flat
3 both ends of plate, which symmetrically bolt, adjustable column 6, and 6 upper end of adjustable column is fixedly connected with the first fixture block 7, and the first folder by fastening bolt 9
Second fixture block 8 is fixedly connected with by the first tightening knob 10 above block 7, while the first fixture block 7 and the second fixture block 8 are combined into use
In the collet of fixed titanium alloy circle 12,1 rear end of pedestal is provided with constraint cylinder 11, and constraint cylinder 11 is wedge shape close to 6 one end of adjustable column.
Wherein, the clip designs that the first fixture block 7 and the second fixture block 8 are combined into cooperate the fixed titanium alloy circle 12 of dedicated head,
It can be fixedly secured mouse head, vibration is reduced to minimum, the redundancy of the first fixture block 7 also allows the titanium alloy of fixed mouse head
Enclose 12 detachable, an experiment mice long-time many experiments uses.
Titanium alloy circle 12 is bonded on experiment mice skull with dental cement, and light weight, bioaffinity is good, is suitble to length
Time experiment, experimental test experiment mice install this titanium alloy circle 12 after half a year, still securely as before, can carry out high-precision
Imaging experiment.
The first adjusting knob 4 is provided on front side of fixer main body 2, right side is provided with the second adjusting knob 5, fixer main body
Graduation mark is indicated respectively on 2 lateral surfaces and close to the position of 5 lower section of the first adjusting knob 4 and the second adjusting knob, and first is adjusted
Knob 4 and the second adjusting knob 5 control AP and ML two of station plate 3 by the gear inside fixer main body 2 respectively
Axial angle is adjusted, i.e., upper and lower and left and right both direction.
As shown in Figures 2 and 3, it fetters below cylinder 11 and support 16 is installed, be fixedly connected on the pedestal 1 of 16 side of cylinder support
Support plate 13, and strip groove 14 is provided among support plate 13, cylinder support 16 is fixedly mounted on support plate by the second tightening knob 15
It can move up and down on 13 and in strip groove 14.
Constraint cylinder 11 is for fettering animal struggle, and swing body, both effectively mouse was prevented to sway, and prevented titanium from closing
Gold ring 12 falls off, and experiment mice is made to have certain move place, and constraint cylinder 11 just can carry out upper-lower height tune with cylinder support
Section.
The experimentation of the utility model is as follows:
Firstly, experiment mice to be mixed up to flat cranium in stereotaxic instrument, site to be recorded is marked on mouse skull；So
Titanium alloy circle 12 is fixed on mouse skull using dental cement afterwards, after dental cement is fully cured, is marked with forsner bit
Three level points, as the reference point for leveling skull in experiment；It waits after a certain period of time, experiment mice is mounted in this fixer
On, mouse body is fitted into constraint cylinder 11, using three reference points for being preset in dental cement surface, passes through the first adjusting knob
10 and second adjusting knob 15 adjust AL and ML axial direction angle, until flat cranium；Electrophysiological recording experiment is carried out later, because
Through flat cranium, electrode can be vertically descended, the depth only rolled into a ball with consideration core to be recorded, so that entire experiment flow is provided with and can operate
Property.
While there has been shown and described that the embodiments of the present invention, for the ordinary skill in the art,
It is understood that these embodiments can be carried out with a variety of variations in the case where not departing from the principles of the present invention and spirit, repaired
Change, replacement and variant, the scope of the utility model is defined by the appended claims and the equivalents thereof.
Claims (5)
1. a kind of conscious mouse head fixer, including pedestal (1), fixer main body (2), station plate (3), adjustable column (6),
First fixture block (7), the second fixture block (8), titanium alloy circle (12), it is characterised in that: the fixer main body (2) is fixedly mounted on base
Front end above seat (1), and be provided with station plate (3) above fixer main body (2), station plate (3) both ends
Symmetrical bolt has adjustable column (6), and adjustable column (6) upper end is fixedly connected with the first fixture block (7) by fastening bolt (9), and
It is fixedly connected with the second fixture block (8) by the first tightening knob (10) above first fixture block (7), while the first fixture block (7) and the
Two fixture blocks (8) are combined into the collet for fixing titanium alloy circle (12).
2. conscious mouse head fixer according to claim 1, it is characterised in that: pedestal (1) rear end is provided with beam
It ties up cylinder (11), and fetters and be equipped with cylinder support (16) below cylinder (11), be fixedly connected on the pedestal (1) of cylinder support (16) side
Support plate (13), and be provided with strip groove (14) among support plate (13), the cylinder support (16) is solid by the second tightening knob (15)
Dingan County is on support plate (13) and can move up and down in strip groove (14).
3. conscious mouse head fixer according to claim 2, it is characterised in that: the constraint cylinder (11) is close to adjustable column
(6) one end is wedge shape.
4. conscious mouse head fixer according to claim 1, it is characterised in that: set on front side of the fixer main body (2)
It is equipped with the first adjusting knob (4), right side is provided with the second adjusting knob (5).
5. conscious mouse head fixer according to claim 4, it is characterised in that: fixer main body (2) lateral surface
Upper and below the first adjusting knob (4) and the second adjusting knob (5) positions indicate graduation mark respectively.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821746677.XU CN209107665U (en) | 2018-10-26 | 2018-10-26 | Conscious mouse head fixer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821746677.XU CN209107665U (en) | 2018-10-26 | 2018-10-26 | Conscious mouse head fixer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN209107665U true CN209107665U (en) | 2019-07-16 |
Family
ID=67202430
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201821746677.XU Active CN209107665U (en) | 2018-10-26 | 2018-10-26 | Conscious mouse head fixer |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN209107665U (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110721004A (en) * | 2019-10-30 | 2020-01-24 | 漯河医学高等专科学校 | Quick positioning and tightening device for laboratory mouse |
| CN111024934A (en) * | 2019-12-27 | 2020-04-17 | 苏州溢博伦光电仪器有限公司 | Vibration reduction type microscopic observation method |
| CN111643213A (en) * | 2020-06-12 | 2020-09-11 | 中国人民解放军空军军医大学 | Murine stereotactic skull leveling inspection and calibration device |
-
2018
- 2018-10-26 CN CN201821746677.XU patent/CN209107665U/en active Active
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110721004A (en) * | 2019-10-30 | 2020-01-24 | 漯河医学高等专科学校 | Quick positioning and tightening device for laboratory mouse |
| CN111024934A (en) * | 2019-12-27 | 2020-04-17 | 苏州溢博伦光电仪器有限公司 | Vibration reduction type microscopic observation method |
| CN111024934B (en) * | 2019-12-27 | 2021-12-07 | 苏州溢博伦光电仪器有限公司 | Vibration reduction type microscopic observation method |
| CN111643213A (en) * | 2020-06-12 | 2020-09-11 | 中国人民解放军空军军医大学 | Murine stereotactic skull leveling inspection and calibration device |
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