CN214908551U

CN214908551U - Adaptation device is implanted to kiwi brain deep nuclear group electrode based on stereotactic headstock

Info

Publication number: CN214908551U
Application number: CN202120368031.8U
Authority: CN
Inventors: 马硕; 姜建; 李殿友
Original assignee: Ruinjin Hospital Affiliated to Shanghai Jiaotong University School of Medicine Co Ltd; Center for Excellence in Brain Science and Intelligence Technology Chinese Academy of Sciences
Current assignee: Ruinjin Hospital Affiliated to Shanghai Jiaotong University School of Medicine Co Ltd; Center for Excellence in Brain Science and Intelligence Technology Chinese Academy of Sciences
Priority date: 2021-02-09
Filing date: 2021-02-09
Publication date: 2021-11-30
Anticipated expiration: 2031-02-09

Abstract

The utility model discloses an adaptation device is implanted to chinese goosebeery deep nuclear group electrode based on stereotactic headstock, this adaptation device are used for with stereotactic headstock, stereotactic head bow and chinese goosebeery skull rigid connection and puncture, including headstock adaptation device, puncture sleeve pipe and puncture guide sleeve subassembly, headstock adaptation device includes T type titanium nail, connection base, connection crossbeam, two extension arms, two connection stands. The utility model discloses can carry out position adjustment according to actual operation after connecting crossbeam, extension arm, connection stand and the three-dimensional orientation headstock is connected among the headstock adapter device, the follow-up operation of being convenient for, for the intracranial implantation electrode of different kiwi fruit skull size, shape difference, different skull connection base mounted position provides great degree of freedom, easily understand the operation and improved work efficiency, simple structure, the implementation of being convenient for.

Description

Adaptation device is implanted to kiwi brain deep nuclear group electrode based on stereotactic headstock

Technical Field

The utility model belongs to the technical field of medical equipment, concretely relates to adaptation device is implanted to kiwi brain deep nucleus group electrode based on stereotactic headstock.

Background

The non-human primate macaque is an important experimental model animal for researching the high-grade cognitive function of human beings, and the main research means for researching neural circuits, such as precise positioning insecticide application, electrophysiological recording, electrical stimulation and the like, of the deep brain structure of the macaque greatly depend on the precise positioning implantation technology of the deep brain nucleus of a large animal. The commercial large animal deep brain nucleus stereotaxic apparatus adopted at present has some deficiencies in the deep brain nucleus positioning implantation operation process, mainly includes: the electrode implantation can be ensured to be relatively accurately implanted in the vertical direction, the positioning device and the skull of the macaque lack stable rigid fixation, the operations of secondary installation such as scanning nuclear magnetic front and back fixation and the like easily cause position deviation, the movable range of the stereotactic device implantation kit is limited, and certain specific parts can not realize the electrode implantation and the like.

Aiming at the defects of the large animal brain deep nucleus stereotaxic device, the utility model discloses the people combines clinical stereotaxic operation experience, finds out that the stereotaxic system based on the human stereotaxic headstock Leksell Frame G has the advantages of multi-angle accurate implantation, rigid fixation with skull, wide movable range and the like, and can well make up the defects of the commercial macaque brain deep nucleus stereotaxic device.

The skull size of a non-human primate macaque is only one fourth of that of a human skull, and the difference in size between the macaque and the human skull causes that a skull fixing component of a Leksell Frame G stereotactic head Frame cannot be well fixed on the macaque skull, so that the Leksell Frame G stereotactic head Frame becomes a main technical problem that a Leksell Frame G stereotactic system cannot be applied to accurate positioning implantation of deep brain nuclei of large animals such as the macaque. To this technical problem, the utility model discloses rely on with stereotactic headstock Leksell Frame G, designed one set and can found the adaptation device of kiwi fruit skull and Leksell Frame G rigid connection, make Leksell Frame G stereotactic headstock can be fixed with the kiwi fruit skull rigidity, effectively connect with human stereotactic headstock and kiwi fruit skull, and combine the kiwi fruit brain size, a set of supplementary surgical instruments are implanted to the kiwi version electrode that matches with it has been specially made, the system has realized that the kiwi fruit is based on the accurate of the deep nuclear group of brain of human stereotactic headstock Leksell Frame G stereotactic system, safety, the directional implantation of wicresoft.

Aiming at the operation of accurate positioning implantation of the brain deep nucleus, the method is mainly implemented by two technical schemes at present, namely a brain deep nucleus accurate positioning technology which is based on a large animal stereotaxic instrument and is used for researching neural loops such as positioning insecticide application, electrophysiological recording, electrical stimulation and the like of the macaca deep nucleus; and secondly, the stereotactic system based on the human Leksell Frame G stereotactic head Frame is used for clinically developing a technology of brain deep nucleus accurate positioning technology of brain deep nucleus electrical stimulation electrode implantation and pathological sampling. The specific technical implementation backgrounds are respectively introduced as follows:

1. the brain deep nucleus accurate positioning implantation scheme based on the large animal stereotaxic instrument:

the brain deep nucleus positioning method of the large animal stereotaxic apparatus is mainly based on a bilateral eye rod, a bilateral ear rod and a dental bar, an anesthetized animal is stably fixed on the stereotaxic apparatus, a mark is arranged on the surface of a skull through an operation, then the stereotaxic apparatus is detached, the relative position of a brain deep part to-be-implanted part and the surface mark of the skull is determined through the assistance of imaging, the anesthetized animal is fixed on the stereotaxic apparatus in the same way as before again, a needle inserting device is horizontally moved according to the obtained relative position, needle insertion is performed through vertical drilling above a target point, and the brain deep nucleus positioning implantation is realized. The brain deep nucleus locating implantation scheme can not realize the oblique implantation of the deep nucleus, and because the brain deep nucleus needs to be fixed in the stereotaxic instrument twice in front and back and the needle inserting parameters need to be obtained by calculating the relative position, and the like, the large animal stereotaxic instrument used for locating the brain deep nucleus is complex in operation and has larger system and random errors.

2. Clinical deep brain nucleus accurate positioning implantation scheme based on human stereotaxic device:

the accurate positioning implantation scheme of deep brain nucleus of clinical brain of the head frame device of human stereotactic, it is that through the location of imaging and stereotactic device guide, put microelectrode, etc. into the intracranial specific target point, treat central nervous system disease or clamp the neurosurgery operation which picks up the pathological sample. At present, the stereotaxic devices used at home and abroad are all bow-shaped positioning instruments, and the principle is a sphere center method. The using steps are as follows: firstly, a scalp is pierced by four long nails to be clamped on a skull, a stereotactic head frame is rigidly fixed on the skull, the stereotactic head frame is used as a reference mark for image positioning, a brain is placed in a three-dimensional space, and Cartesian coordinates (X, Y and Z) of a target point are measured. And secondly, adjusting X, Y and Z arms on the stereotaxic apparatus to enable the circle center of the arc-shaped bow on the stereotaxic apparatus to coincide with the target point. Finally, according to the adjusted X, Y and Z coordinates, the bow-shaped orientation instrument is installed on the frame, and the electrode is placed from any point on the arc-shaped bow in the direction perpendicular to the arc-shaped tangent line, and can pass through the preset sphere center, so that the electrode embedding of the target point is completed. The positioning system has the advantages of accuracy and simplicity. Despite the advantages, because the skull of the macaque is small in size (only equal to about 1/4 of the human skull) and thin, the long nail used for rigidly fixing the stereotactic head frame on the skull cannot meet the requirement of puncturing the scalp of the macaque to be stuck on the skull, and the skull is easy to puncture and hurt the intracranial tissues in the process of nail feeding. How to firmly and safely fix the human stereotactic head frame on the skull of experimental large animals such as macaques has important significance for realizing the accurate positioning and orientation implantation of the deep nucleus of the brain of the macaque. But at present, no corresponding device can assist in realizing the firm and safe connection between the macaque skull and the human stereotactic head frame.

SUMMERY OF THE UTILITY MODEL

In order to solve the defects existing in the prior art, the utility model provides a macaque brain deep nucleus group electrode implantation adapting device based on a stereotactic headstock.

In order to solve the technical problem, the utility model provides a following technical scheme:

the utility model provides a macaque brain deep nucleus group electrode implantation adapter device based on stereotactic headstock, is used for with stereotactic headstock, stereotactic head bow and macaque skull rigid connection and puncture, including headstock adapter device, puncture sleeve pipe and puncture guide sleeve pipe subassembly, headstock adapter device includes T type titanium nail, connection base, connecting beam, two extension arms, two connection columns, T type titanium nail is used for anchoring on the macaque occipital skull, the surface of T type titanium nail is paintd and is covered with dental cement, the connection base is embedded to be fixed in on the dental cement, the slope portion and the connection base of connecting beam bottom pass through bolted connection, the draw-in groove at connecting beam both ends respectively with two extension arms through bolted connection, the wedge connecting portion of extension length direction one end passes through bolted connection with the top of connection column, the connecting upright post is connected with the inner side of the three-dimensional directional head frame through a bolt; the puncture sleeve penetrates through the guide sleeve assembly from top to bottom, and the guide sleeve assembly is arranged on a head bow sliding block of the three-dimensional directional head bow.

As an optimal technical scheme of the utility model, T type titanium nail includes square body structure and cylinder structure, square body structure an organic whole sets up in the one end of cylinder structure axle center direction.

As a preferred technical scheme of the utility model, connection base is including the first base body and the second base body of an organic whole setting, first base body and second base body are for having the square body structure of setting for length, width, height dimension of first base body are less than the size of second base body, it is equipped with two base connecting holes to run through on first base body and the second base body.

As a preferred technical scheme of the utility model, the horizontal crossbeam body, the vertical crossbeam body and the slope portion that the connection crossbeam set up including an organic whole, be equipped with the draw-in groove on the lower surface at horizontal crossbeam body length direction both ends respectively, the tank bottom of draw-in groove is equipped with the crossbeam connecting hole, the vertical crossbeam body sets up perpendicularly on the lower surface of the horizontal crossbeam body, the square body structure of the length and width height is specifically set for to the slope portion, the contained angle setting is set for with vertical crossbeam body slope in any side of slope portion, be equipped with two slope connecting holes in the slope portion, bolted connection is passed through with connection base's base connecting hole to slope connecting hole 35 in the slope portion.

As a preferred technical solution of the present invention, the extension arm includes an extension arm body and a wedge-shaped connection portion, which are integrally disposed, the extension arm body is provided with at least one second extension arm connection hole along a length direction thereof, the wedge-shaped connection portion is disposed on one side of the extension arm body along the length direction, and the wedge-shaped connection portion is provided with a first extension arm connection hole; the wedge-shaped connecting part is clamped in the clamping grooves at the two ends of the connecting beam and connects the first extension arm connecting hole formed in the wedge-shaped connecting part with the beam connecting hole through a bolt.

As a preferred technical scheme of the utility model, the both sides of connecting stand length direction are equipped with the wedge spliced pole, the top of connecting the stand and be located and be equipped with stand top recess between two wedge spliced poles, the tank bottom of stand top recess is equipped with stand top connecting hole, wedge spliced pole length direction's the outside is equipped with stand connecting groove on the surface, be equipped with the stand connecting hole on one side lateral wall of stand connecting groove.

As a preferred technical scheme of the utility model, the puncture sleeve pipe includes spacing post and puncture needle tubing of an organic whole setting, puncture guide sleeve subassembly includes guide post and lower guide post.

As a preferred technical solution of the present invention, wedge-shaped head frame grooves are symmetrically disposed on the inner surface of the stereotactic head frame and at positions close to the back of the brain, head frame connection holes are disposed on the upper surface of the stereotactic head frame and at the front side of the wedge-shaped head frame grooves, and the head frame connection holes are communicated with the wedge-shaped head frame grooves; the wedge-shaped head frame groove is matched with the wedge-shaped connecting column, so that the wedge-shaped connecting column is clamped in the wedge-shaped head frame groove, and the stand column connecting hole and the head frame connecting hole are connected through a bolt.

As a preferred technical solution of the present invention, the stereospecific head bow is provided with two head bow ear rings and a head bow slider, one end of each two head bow ear ring is respectively disposed at two ends of the stereospecific head bow in the length direction, the other end of each head bow ear ring is further mounted on the stereospecific head frame, the head bow slider is slidably connected to the stereospecific head bow along the length direction of the stereospecific head bow, the head bow slider is further provided with a slider mounting part for mounting the puncture guide sleeve pipe assembly, and the slider mounting part is mounted on the movable head bow slider in the head bow linear direction; the puncture sleeve pipe runs through from top to bottom and wears to locate in guide post and the guide post down, it sets up on the slider installation department with guide post down to go up the guide post.

The utility model discloses compare in prior art, have following beneficial effect:

the utility model discloses a T type titanium nail of kiwi fruit skull installation and skull connection base to and connect the headstock adapter device that crossbeam, extension arm, connection stand etc. constitute, because the skull undersize of non-human primate kiwi fruit through the solution, and can not use the device of this ripe brain deep nucleus accurate positioning of stereotactic headstock to carry out the technical problem of brain deep nucleus location, indirectly solved the difficult problem of the accurate location of kiwi fruit brain deep nucleus multi-angle in the basic scientific research.

The utility model discloses can carry out position adjustment according to actual operation after connecting crossbeam, extension arm, connection stand and the three-dimensional orientation headstock is connected among the headstock adapter device, the follow-up operation of being convenient for, for the intracranial implantation electrode of different kiwi fruit skull size, shape difference, different skull connection base mounted position provides great degree of freedom, easily understand the operation and improved work efficiency, simple structure, the implementation of being convenient for.

Drawings

Fig. 1 is a schematic structural view of a T-shaped titanium nail of the present invention.

Fig. 2 is a schematic structural diagram of the connection base of the present invention.

Fig. 3 is a schematic structural diagram of the middle connecting beam of the present invention.

Fig. 4 is a schematic structural diagram of the extension arm of the present invention.

Fig. 5 is a schematic structural diagram of the middle connection pillar of the present invention.

Fig. 6 is a schematic structural view of the middle puncture cannula of the present invention.

Fig. 7 is a schematic view of a puncture guide sleeve assembly according to the present invention.

Fig. 8 is a schematic view of the stereotactic headgear of the present invention.

Fig. 9 is a schematic structural view of the middle stereospecific head bow of the present invention.

Detailed Description

The preferred embodiments of the present invention will be described in conjunction with the accompanying drawings, and it will be understood that they are presented herein only to illustrate and explain the present invention, and not to limit the present invention.

In the description of the present invention, it should be understood that the terms "left", "right", etc. indicate the orientation or positional relationship based on the orientation or positional relationship shown in fig. 1 of the drawings of the specification, which is only for convenience of description and simplification of description, but do not indicate or imply that the device or element referred to must have a specific orientation, be constructed in a specific orientation, and be operated, and thus should not be construed as limiting the present invention.

In the description of the present invention, it is to be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "connected" and "connected" are to be construed broadly, and may for example be fixedly connected, detachably connected, or integrally connected; may be directly connected or indirectly connected through an intermediate. The specific meaning of the above terms in the present invention can be understood in specific cases to those skilled in the art.

Example 1

In order to achieve the objective of the present invention, as shown in fig. 1 to 9, in one embodiment of the present invention, an adaptive apparatus for implanting electrodes in deep nuclei of the brain of a macaque based on a stereotactic head frame is provided for rigidly connecting and puncturing the stereotactic head frame 8, the stereotactic head bow 9 and the skull of the macaque. This adaptation device is implanted to deep nuclear group electrode of kiwi fruit includes headstock adaptation device, puncture sleeve 6 and puncture guide sleeve subassembly 7, headstock adaptation device includes T type titanium nail 1, connection base 2, connection crossbeam 3, two extension arms 4, two connection upright posts 5, T type titanium nail 1 is used for anchoring on the skull of kiwi fruit occipitalia, the surface of T type titanium nail 1 is paintd and is stamped dental cement, 2 embedded being fixed in on the dental cement of connection base.

As shown in fig. 1, the T-shaped titanium nail 1 includes a square structure and a cylindrical structure, and the square structure is integrally disposed at one end of the cylindrical structure in the axial direction.

As shown in fig. 2, the connection base 2 includes a first base body 21 and a second base body 22 which are integrally arranged, the first base body 21 and the second base body 22 are of a square structure with a set length, width and height, the length, width and height of the first base body 21 are smaller than those of the second base body 22, and two base connection holes 23 are formed in the first base body 21 and the second base body 22 in a penetrating manner.

As shown in fig. 3, the connecting beam 3 includes a horizontal beam body 31, a vertical beam body 32 and a slope portion 33 that are integrally provided, the lower surfaces at both ends of the length direction of the horizontal beam body 31 are respectively provided with a clamping groove 34, the bottom of the clamping groove 34 is provided with a beam connecting hole 36, the vertical beam body 32 is perpendicularly provided on the lower surface of the horizontal beam body 31, the slope portion 33 is a square body structure with a specific length and width, any side surface of the slope portion 33 and the vertical beam body 32 are inclined to set an included angle, the slope portion 33 is provided with two slope connecting holes 35, and the slope connecting hole 35 on the slope portion 33 is connected with the base connecting hole of the connecting base 2 through a bolt.

As shown in fig. 4, the extension arm 4 includes an extension arm body 41 and a wedge-shaped connection portion 42 that are integrally disposed, wherein 3 second extension arm connection holes 43 are disposed on the extension arm body 41 and along the length direction thereof, the wedge-shaped connection portion 42 is disposed on one side of the extension arm body 41 in the length direction, and a first extension arm connection hole 44 is disposed on the wedge-shaped connection portion 42. The wedge-shaped connecting portion 42 is clamped in the clamping groove 34 at the two ends of the connecting beam 3 and connects the first extension arm connecting hole 44 formed on the connecting groove and the beam connecting hole 36 through a bolt.

As shown in fig. 5, the two sides of the connecting column 5 in the length direction are provided with wedge-shaped connecting columns 51, the top of the connecting column 5 is provided with a column top groove 52 between the two wedge-shaped connecting columns 51, the bottom of the column top groove 52 is provided with a column top connecting hole 53, the outer side surface of the wedge-shaped connecting column 51 in the length direction is provided with a column connecting groove 54, and one side wall of the column connecting groove 54 is provided with a column connecting hole 55.

As shown in fig. 6, the puncture cannula 6 comprises a limiting column and a puncture needle tube which are integrally arranged, and as shown in fig. 7, the puncture guide cannula assembly 7 comprises an upper guide column 71 and a lower guide column 72.

As shown in fig. 8, a wedge-shaped head holder groove 81 is symmetrically formed on the inner surface of the stereotactic head 8 at a position close to the back of the brain, and a head holder connection hole 82 is formed on the upper surface of the stereotactic head 8 at the front side of the wedge-shaped head holder groove 81, and the head holder connection hole 82 is communicated with the wedge-shaped head holder groove 81.

The wedge-shaped head frame groove 81 is matched with the wedge-shaped connecting column 51, so that the wedge-shaped connecting column 51 is clamped in the wedge-shaped head frame groove 81, and the column connecting hole and the head frame connecting hole 82 are connected through a bolt.

As shown in fig. 9, the head bow 9 is provided with a two-head bow ear ring 91 and a head bow slider 92, one end of the two-head bow ear ring 91 is respectively disposed at two ends of the length direction of the head bow 9, the other end of the head bow ear ring 91 is further mounted on the head bow 8, the head bow slider 92 is slidably connected to the head bow 9 along the length direction of the head bow 9, the head bow slider 92 is further provided with a slider mounting portion 93 for mounting a puncture guide cannula component, and the slider mounting portion 93 is movably mounted on the head bow slider 92 in the head bow normal line direction. The puncture cannula 6 penetrates through the upper guide column 71 and the lower guide column 72 from top to bottom, and the upper guide column 71 and the lower guide column 72 are arranged on the slider mounting portion 93.

The utility model also provides an utilize method that adaptation device was implanted to kiwi brain deep nuclear group electrode based on stereotactic headstock to implant electrode, including following step:

s1, establishing a Cartesian coordinate system by relying on the stereotactic head frame 8, and determining coordinates of a nucleus of the deep part of the head of the macaque in the Cartesian coordinate system; the method comprises the following steps:

s11, punching holes in the skull of the occiput of the macaque under general anesthesia and inserting the T-shaped bone nails 1, and tightly pressing and reinforcing the T-shaped bone nails 1 by the outer end gaskets 11 and the nuts;

s12, smearing dental cement on the surface of the T-shaped bone nail 1 and inlaying the connecting base 2 on the cement;

s13, after the connection base 2 is firmly installed, the connection base 2 is fastened in the base connection hole 23 on the connection base 2 and the slope connection hole 35 on the slope part 33 through bolts, and therefore the connection base 2 is connected with the connection cross beam 3; then, according to the relative position of the skull and the adapting device, the optimal second extension arm connecting hole 43 is selected on the extension arm 4 at the position of the clamping groove 34 of the sliding connecting beam 3 to fix the extension arm 4 and the connecting beam 3; the wedge-shaped connecting part 42 is clamped in the column top groove 52 of the connecting column 5 and the first extension arm connecting hole 44 and the column top connecting hole 53 on the wedge-shaped connecting part are connected through a bolt, so that the extension arm 4 and the connecting column 5 are fixed; then the wedge-shaped connecting column 51 of the connecting upright post 5 is clamped in the wedge-shaped headstock groove 81, and the upright post connecting hole and the headstock connecting hole 82 are connected through a bolt, so that the connecting upright post 5 is rigidly connected with the three-dimensional orientation headstock;

s14, mounting a positioning frame along the stereotactic head frame around the skull, and performing skull MRI scanning;

s15, importing the MRI data of the cranium of the macaque into a stereotactic operation planning system, determining the relative position of a nuclear group of the deep part of the brain of the macaque under the current Cartesian coordinate system determined by the stereotactic head frame and a target needle insertion path avoiding the great vessels by means of software, and automatically calculating the corresponding head bow assembly X, Y, Z coordinate and the needle insertion path coordinate.

S2, implanting an electrode into the cranium of a macaque, which comprises the following steps:

s21, correspondingly adjusting the connecting position of the stereotactic head bow and the stereotactic head bow according to a head bow assembly X, Y, Z coordinate preset by an operation planning system, namely a stereotactic head bow scale groove, a stereotactic head bow front and back scale and a stereotactic head bow earring connecting scale, and placing a deep brain target nucleus in the spherical center of the spherical surface where the head bow is located;

s22, determining the spherical surface position of the head arch around the spherical center of the target nucleus and the needle insertion selection radius according to the head arch earring angle R and the head arch slide block Arc coordinates of the needle insertion path preset by the operation planning system;

s23, installing a puncture guide cannula on the cephalic arch, inserting the puncture cannula into the cranium under the guide of the puncture guide cannula, stopping inserting the needle when the needle is inserted to 19 cm, and positioning the tip at the core ball of the deep part of the brain, namely the ball center of the cephalic arch;

s24, taking out the puncture cannula core to make the arc puncture cannula cavity empty;

s25, implanting an electrode in the empty puncture cannula lumen, wherein the electrode enters into the cranium under the restriction of the puncture cannula lumen until the electrode tail end reaches the outlet of the puncture cannula, and at the moment, the electrode body is under the restriction and protection of the puncture cannula lumen, and the electrode body contacts with the target point through the tail end opening of the puncture cannula.

Finally, it should be noted that: although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that modifications may be made to the embodiments described in the foregoing embodiments, or equivalents may be substituted for elements thereof. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. A macaque brain deep nucleus group electrode implantation adapting device based on a stereotactic headstock is used for rigidly connecting and puncturing the stereotactic headstock, a stereotactic head bow and a macaque skull, and is characterized by comprising the headstock adapting device, a puncturing sleeve and a puncturing guide sleeve assembly, wherein the headstock adapting device comprises a T-shaped titanium nail, a connecting base, a connecting beam, two extending arms and two connecting stand columns, the T-shaped titanium nail is used for anchoring on the macaque occipital skull, dental cement is coated on the surface of the T-shaped titanium nail, the connecting base is fixed on the dental cement in an embedded manner, a slope part at the bottom of the connecting beam is connected with the connecting base through bolts, clamping grooves at two ends of the connecting beam are respectively connected with the two extending arms through bolts, and a wedge-shaped connecting part at one end in the length direction of the extending arms is connected with the top of the connecting stand columns through bolts, the connecting upright post is connected with the inner side of the three-dimensional directional head frame through a bolt; the puncture sleeve penetrates through the guide sleeve assembly from top to bottom, and the guide sleeve assembly is arranged on a head bow sliding block of the three-dimensional directional head bow.

2. The deep yangonian nucleus electrode implantation adaptive device based on the stereotactic headstock as claimed in claim 1, wherein said T-shaped titanium nail comprises a square structure and a cylinder structure, said square structure is integrally disposed at one end of the cylinder structure in the axial direction.

3. The device of claim 1, wherein the connection base comprises a first base body and a second base body which are integrally arranged, the first base body and the second base body are of a square structure with a set length, width and height, the length, width and height of the first base body are smaller than those of the second base body, and two base connection holes are formed in the first base body and the second base body in a penetrating mode.

4. The deep nucleus pulposus electrode implantation adapting device of the macaque based on the stereotactic headstock of claim 1, wherein the connecting beam comprises a horizontal beam body, a vertical beam body and a slope portion which are integrally arranged, the lower surfaces of the two ends of the length direction of the horizontal beam body are respectively provided with a clamping groove, the bottom of the clamping groove is provided with a beam connecting hole, the vertical beam body is vertically arranged on the lower surface of the horizontal beam body, the slope portion is a square body structure with the length, the width and the height specifically set, the inclined angle setting is set between any side surface of the slope portion and the vertical beam body in an inclined mode, two slope connecting holes are arranged on the slope portion, and the slope connecting hole 35 on the slope portion is connected with the base connecting hole of the connecting base through a bolt.

5. The adaptation device for macaque brain deep nucleus electrode implantation based on the stereotactic headstock of claim 1, wherein the extension arm comprises an extension arm body and a wedge-shaped connecting part which are integrally arranged, the extension arm body is provided with at least one second extension arm connecting hole along the length direction of the extension arm body, the wedge-shaped connecting part is arranged at one side of the length direction of the extension arm body, and the wedge-shaped connecting part is provided with a first extension arm connecting hole; the wedge-shaped connecting part is clamped in the clamping grooves at the two ends of the connecting beam and connects the first extension arm connecting hole formed in the wedge-shaped connecting part with the beam connecting hole through a bolt.

6. The adaptation device is implanted to kiwi brain deep nucleus group electrode based on stereotactic headstock of claim 1, characterized in that, the both sides of connecting stand length direction are equipped with the wedge spliced pole, the top of connecting the stand just is located and is equipped with stand top recess between two wedge spliced poles, the tank bottom of stand top recess is equipped with stand top connecting hole, be equipped with stand connecting groove on the outside surface of wedge spliced pole length direction, be equipped with the stand connecting hole on one side lateral wall of stand connecting groove.

7. The stereotactic headstock-based deep macaque nucleus pulposus electrode implantation adapting device as claimed in claim 1, wherein said puncture cannula comprises an integrally arranged limiting column and a puncture needle tube, and said puncture guide cannula assembly comprises an upper guide column and a lower guide column.

8. The stereotactic headstock-based deep macaque nuclei electrode implantation adapting device according to claim 1, wherein wedge-shaped headstock grooves are symmetrically formed on the inner side surface of the stereotactic headstock and at positions close to the back side of the brain, headstock connecting holes are formed on the upper surface of the stereotactic headstock and at the front side of the wedge-shaped headstock grooves, and the headstock connecting holes are communicated with the wedge-shaped headstock grooves; the wedge-shaped head frame groove is matched with the wedge-shaped connecting column, so that the wedge-shaped connecting column is clamped in the wedge-shaped head frame groove, and the stand column connecting hole and the head frame connecting hole are connected through a bolt.

9. The deep macaque brain nucleus electrode implantation adapting device based on the stereotactic head frame according to claim 1, wherein a two-head bow ear ring and a head bow slider are arranged on the stereotactic head bow, one end of the two-head bow ear ring is respectively arranged at two ends of the length direction of the stereotactic head bow, the other end of the head bow ear ring is also arranged on the stereotactic head frame, the head bow slider is connected to the stereotactic head bow in a sliding manner along the length direction of the stereotactic head bow, a slider mounting part for mounting a puncture guide cannula assembly is further arranged on the head bow slider, and the slider mounting part is movably mounted on the head bow slider in the head bow normal direction; the puncture sleeve pipe runs through from top to bottom and wears to locate in guide post and the guide post down, it sets up on the slider installation department with guide post down to go up the guide post.