CN209086257U - A kind of biosensor improving sample introduction speed - Google Patents
A kind of biosensor improving sample introduction speed Download PDFInfo
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- CN209086257U CN209086257U CN201821863739.5U CN201821863739U CN209086257U CN 209086257 U CN209086257 U CN 209086257U CN 201821863739 U CN201821863739 U CN 201821863739U CN 209086257 U CN209086257 U CN 209086257U
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Abstract
The utility model discloses a kind of biosensors for improving sample introduction speed, it successively includes substrate layer, electrode layer, insulating layer, reagent layer, the hydrophilic combination layer of double-sided adhesive and shielding layer from bottom to up, insulating layer is equipped with the window exposure electrode layer working portion, the window end punching setting cavernous structure；The biosensor end, the two sides abnormity for corresponding to cavernous structure are punched two side angles, and biosensor end processes to form " volcano " type structure.Substrate layer end cut mentioned by the utility model forms cavernous structure, and it is to improve one of the important implementation of biosensor sample introduction speed that cooperative end part abnormity punching two sides right angle, which processes and to form above-mentioned " volcano " type structure,.
Description
Technical field
The utility model relates to biosensors, and the bio-sensing of target substance is especially detected from blood sample
Device more particularly to a kind of biosensor for improving sample introduction speed.
Background technique
It is well known that being widely applied in medical field disposable biological sensor (such as all kinds of test papers)
In terms of quantitative determining the multiple analytes in body fluid.Such as: blood glucose test results can instruct to judge whether to insulin or
Person's other medicines intervention helps sufferer to carry out glucose-lowering treatment, and blood sugar test paper has been made by world's diabetic patients popularization at present
With.
Generally, blood sugar test paper include substrate layer and on electrode layer, electrode layer includes at least one reference electrode
With at least one working electrode, it is coated with the insulating layer of electrical insulation property on electrode layer, designs one section of square in insulation level
Shape hollow-out part, with the hydrophilic Loading channel for combining one acquisition blood sample of common building and being detected of the double-sided adhesive on the upper layer.
The design of Loading channel has an important influence test result.The blood sugar test paper of current brands many on the market adds
Similar in sample channel design, being commonly test paper medium design has an elongated channel, and one end is located at the open end of test paper
For acquiring blood, the exhaust outlet of air is excluded when another port is as acquisition blood sample.
It is formed by pain in order to reduce detection blood volume used and reduce the size depth for the wound taken a blood sample, at present
Test paper Loading channel on the market is usually very narrow, due to this narrow design, blood can be made to become slow full of sample room
It is slow and difficult.According to the feedback of some clinical patients, the blood sampling sites such as finger tightly withstand test paper to user in use
Sample introduction end, it is likely that can cause blood sample that cannot will cause big when sucking off and on quickly in time full of sample detection room
When small sample volume.In addition for the not nimble user of some eyesights or hand, blood sample is difficult to be directed at Loading channel
Entrance causes sample-adding to fail.When blood sample enough in time can not enter sensing chamber, eventually possible testing result mistake deviates real
Actual value, there is error message in all Clinical interventions after causing, by taking blood sugar test paper as an example, if testing result deviates reality
Value may manage therapeutic process dosage to insulin later and mistake occurs, the critical life security to sufferer when serious.
Summary of the invention
In order to overcome shortcoming and deficiency existing in the prior art, the purpose of this utility model is to provide it is a kind of improve into
The biosensor of sample speed, the biosensor can promote blood testing sample-adding aspect the success rate of sample introduction, guarantee to survey
Examination is gone on smoothly.
The technical scheme adopted by the utility model to solve the technical problem is as follows:
It is a kind of improve sample introduction speed biosensor, the sensor from bottom to up successively include substrate layer, electrode layer,
The hydrophilic combination layer of insulating layer, reagent layer, double-sided adhesive and shielding layer, insulating layer are equipped with the window exposure electrode layer work department
Point, the window end punching setting cavernous structure；The two sides abnormity punching of the sensor end, the corresponding cavernous structure
Fall two side angles, biosensor end processes to form " volcano " type structure.
The end of the electrode layer crosses white space, and cavernous structure will not encounter the electrode layer.
The substrate layer end is only arranged in the cavernous structure.
The type of the punching is not limited to round, elliptical shape or rectangular, and punching implementation is laser punching or mould
Has mechanical punching.
Two sensors are head to head placed in the production process, are taken through laser and are punched to form circular hole, it is subsequent again
To hemisect, i.e., the cavernous structure of final each sensor is cambered design.
The abnormity punching: punching angle avoids cutting to the electrode layer, and ensures the sensor after abnormity punching
End and blood sampling site contact surface are not less than the 1/3 of the sensor overall width.
The punching angle is 30-45 °, i.e. the angle of die cut edge and sensor end is 30-45 °.
The beneficial effect of the utility model sensor is:
(1) a large number of experiments show that, which can promote sample introduction for blood testing sample-adding aspect
Success rate, it is final to guarantee that test is gone on smoothly.
(2) sensor manufacturing process of the utility model is simple, is easy to be mass produced, practical, has market price
Value.
Detailed description of the invention
Fig. 1 is the perspective exploded view of the utility model biosensor；
Wherein, 1- substrate layer, 2- electrode layer, 3- insulating layer, 31- sample introduction end aperture, 32- reagent layer, 4- double-sided adhesive are hydrophilic
Combination layer, 5- shielding layer, 51-T shape outlet passageway, the biosensor in 6- manufacturing process, 61- abnormity punching, after 7- molding
Biosensor.
Fig. 2 is the special-shaped die cut section enlarged drawing of the utility model biosensor.
Specific embodiment
The utility model is described further with reference to the accompanying drawings and examples.
Shown in Figure 1, the biosensor of the raising sample introduction speed of the present embodiment, successively includes substrate layer from bottom to up
1, the hydrophilic combination layer 4 of electrode layer 2, insulating layer 3, reagent layer 32, double-sided adhesive and shielding layer 5, insulating layer 3 are equipped with window exposure electricity
Pole 2 working portion of layer, punch-cuts form cavernous structure (specifically on 1 end of substrate layer again after printing insulating layer 3
It is that above-mentioned window end punching setting forms sample introduction end aperture 31), and in biosensor end, above-mentioned corresponding cavernous structure
The punching of two sides abnormity 61 cut away two sides right angle portions, biosensor end processes to form " volcano " type structure.In shielding layer 5
It is equipped with T shape outlet passageway 51.
Rectangle white space is crossed in 2 one end of electrode layer, is beaten in 1 bottom end injection port position of biosensor substrate layer
Hole, punch position are located in above-mentioned rectangle white space, do not influence the normal function of electrode；Later in electrode layer 2 and insulating layer 3
The window's position collectively formed uniformly fills reagent and forms reagent layer 32, then is bonded the common shape of the hydrophilic combination layer 4 of double-sided adhesive
At the sample intake passage of conversion zone.
The punch-cuts sample introduction end aperture 31 on substrate, the subsequent abnormity of cooperation are punched 61 liang again after printing insulating layer 3
Side right angle portions are processed to form biosensor bottom end " volcano " type structure, advantageously improve and sample to test paper test sample introduction
Journey, using more convenient, test result is more acurrate.
Type is punched on the substrate of sample intake passage position and is not limited to round, elliptical shape or rectangular, and punching implementation can
To be realized by laser punching and mould machine punching, can requirement according to sensor to sample introduction and appearance, test, selection are most
Applicable technical solution.The size of cavernous structure is specifically determined according to the size of sensor.
The sensor of two the present embodiment in the production process, is head to head arranged, and is taken through laser and is punched to form circular hole,
It is subsequent again to hemisect, therefore the punching of each sensor is cambered design (preferably semicircle design).
So that blood sample introduction face is deformed into semicircular sector face from rectangle, blood sample connects with hydrophilic layer for substrate " semicircle " punching design
Contacting surface product increases, sample introduction speed and success rate are promoted, and manufacturing process is simple, is easy to be mass produced, practical.
Two sides right angle is cut away in the two sides abnormity punching 61 of the end of the present embodiment biosensor, corresponding cavernous structure, i.e.,
Biosensor end processes to form " volcano " type structure, it is ensured that and biosensor sample introduction region directly contacts blood sampling site,
The deviation for avoiding user from may cause using position has ensured the success rate of sample introduction.
The two sides abnormity of corresponding cavernous structure is punched 61 right angle portions, and punching angle avoids cutting to electrode layer 2, and ensures
Sensor end and blood sampling site contact surface are not less than the 1/3 of sensor overall width after abnormity punching 61；Punching angle is 30-
45°.Preferably, the present embodiment selects with the punching angle on bottom edge to be 37 °, and the bottom end width after punching is 3.3mm, is detailed in figure
2。
The foregoing is merely the preference embodiments of the utility model, do not constitute to scope of protection of the utility model
It limits.Any any modifications, equivalent replacements, and improvements made within spirit of the present utility model and principle etc. should all include
Within the claims of the utility model.
Claims (7)
1. a kind of biosensor for improving sample introduction speed, which is characterized in that the sensor successively includes substrate from bottom to up
The hydrophilic combination layer of layer, electrode layer, insulating layer, reagent layer, double-sided adhesive and shielding layer, insulating layer are equipped with the window exposure electrode
Layer working portion, the window end punching setting cavernous structure；The two sides of the sensor end, the corresponding cavernous structure
Abnormity is punched two side angles, and biosensor end processes to form " volcano " type structure.
2. a kind of biosensor for improving sample introduction speed as described in claim 1, which is characterized in that the end of the electrode layer
Portion crosses white space, and cavernous structure will not encounter the electrode layer.
3. a kind of biosensor for improving sample introduction speed as claimed in claim 2, which is characterized in that the cavernous structure is only
The substrate layer end is set.
4. a kind of biosensor of raising sample introduction speed as described in claim 1-3 is one of any, which is characterized in that described
The type of punching is not limited to round, elliptical shape or rectangular, and punching implementation is laser punching or mould machine punching.
5. a kind of biosensor for improving sample introduction speed as claimed in claim 4, which is characterized in that two sensors
It head to head places in the production process, is taken through laser and is punched to form circular hole, it is subsequent again to hemisect, i.e., it is final each described
The cavernous structure of sensor is cambered design.
6. a kind of biosensor of raising sample introduction speed as described in claim 1-3 is one of any, which is characterized in that described
Abnormity punching: punching angle avoids cutting to the electrode layer, and ensures the sensor end and blood sampling portion after abnormity punching
Position contact surface is not less than the 1/3 of the sensor overall width.
7. a kind of biosensor for improving sample introduction speed as claimed in claim 6, which is characterized in that the punching angle is
30-45 °, i.e. the angle of die cut edge and sensor end is 30-45 °.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201821863739.5U CN209086257U (en) | 2018-11-13 | 2018-11-13 | A kind of biosensor improving sample introduction speed |
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| CN201821863739.5U CN209086257U (en) | 2018-11-13 | 2018-11-13 | A kind of biosensor improving sample introduction speed |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111879827A (en) * | 2020-06-15 | 2020-11-03 | 上海集成电路研发中心有限公司 | Flexible sensor structure and preparation method thereof |
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2018
- 2018-11-13 CN CN201821863739.5U patent/CN209086257U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111879827A (en) * | 2020-06-15 | 2020-11-03 | 上海集成电路研发中心有限公司 | Flexible sensor structure and preparation method thereof |
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Effective date of registration: 20220117 Address after: 212300 No. 5 Baisheng Road, Danyang Development Zone, Zhenjiang City, Jiangsu Province Patentee after: Jiangsu Yuyue kailite Biotechnology Co.,Ltd. Address before: 212300 Yunyang Industrial Park, Danyang City, Zhenjiang City, Jiangsu Province Patentee before: JIANGSU YUYUE MEDICAL EQUIPMENT&SUPPLY Co.,Ltd. Patentee before: NANJING YUWELL SOFTWARE TECHNOLOGY Co.,Ltd. Patentee before: SUZHOU YUYUE MEDICAL TECHNOLOGY Co.,Ltd. Patentee before: JIANGSU YUYUE INFORMATION TECHNOLOGY SYSTEM Co.,Ltd. |
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| TR01 | Transfer of patent right |