CN208893220U - A kind of device for extraction polymethoxyflavone in the dried immature fruit of citron orange - Google Patents
A kind of device for extraction polymethoxyflavone in the dried immature fruit of citron orange Download PDFInfo
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- CN208893220U CN208893220U CN201820991174.2U CN201820991174U CN208893220U CN 208893220 U CN208893220 U CN 208893220U CN 201820991174 U CN201820991174 U CN 201820991174U CN 208893220 U CN208893220 U CN 208893220U
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Abstract
The utility model relates to traditional Chinese medicine extyaction apparatus fields, disclose a kind of for extracting the device of polymethoxyflavone in the dried immature fruit of citron orange.It is created by the utility model, on the one hand the complete process flow comprising dried immature fruit of citron orange crushing, effective component refluxing extraction, adsorption and desorption and condensing crystallizing etc. can be automatically performed, and it is whole without artificial participation, so as to greatly promote the degree of automation of whole device, reduction human cost；On the other hand, due to applying a large amount of metering pump and related sensor in extraction element, the dosing and environmental parameter of each processing links can be accurately controlled according to existing mature technology method, and the efficient absorption feature by utilizing macroporous absorbent resin, it may insure the high efficiency that drug ingredient extracts, the utilization rate of the dried immature fruit of citron orange and the yield of final polymethoxyflavone are promoted, to be conducive to reduce drug market price, promotes the tremendous development of medical and health care system.
Description
Technical field
The utility model belongs to traditional Chinese medicine extyaction apparatus field, and in particular to one kind is for extracting more first in the dried immature fruit of citron orange
The device of oxygroup flavones.
Background technique
The dried immature fruit of citron orange is the drying young fruit of Rutaceae bitter orange and its variety sweet orange, and property is bitter, pungent, sour, warm, returns spleen, stomach meridian,
With relieving stagnant Qi disperse accumulation, the effect of eliminating phlegm and dispersing mass.Brass class, volatile oil and a small amount of alkaloid are mainly contained in the dried immature fruit of citron orange,
In Flavonoid substances not only there is antibacterial, antiviral, anti-inflammatory and vasorelaxation action, also have and inhibit lipid peroxy
Change effect, platelet aggregation and a large amount of enzymes activity, and the permeability and brittleness of capillary can be improved, it is especially more
Methoxy flavone, with the pharmacological actions such as antiviral, antibacterial, antitumor, anti-oxidant, resisting cardiovascular disease, its synthesis
With huge practical value.
As the utility value of various natural constituents increases year by year, it is also more aobvious that these effective components are extracted from plants
It is important, but the technique for extracting polymethoxyflavone from the dried immature fruit of citron orange also generally existing automation difference and extraction efficiency are low
Problem, so that human cost is higher, drug market price is more expensive, is unfavorable for the tremendous development of medical and health care system.
Utility model content
In order to solve the problems, such as that aforementioned existing extraction process technology, the utility model aim are to provide a kind of for the dried immature fruit of citron orange
The middle device for extracting polymethoxyflavone.
The technology employed by the present utility model is
A kind of device for extraction polymethoxyflavone in the dried immature fruit of citron orange, including crusher, grinding mill, electric gate valve, heating
Tank, the first ethyl alcohol holding vessel, the first metering pump, condenser, extracting solution holding vessel, the second ethyl alcohol holding vessel, the second metering pump,
Three metering pumps, two into one go out type three-way magnetic valve, adsorption plant, one-in-and-two-out type three-way magnetic valve, eluent holding vessel, the 4th
Metering pump, condensing crystallizing equipment and industrial personal computer, wherein store concentration between 60~80% in the first ethyl alcohol holding vessel
Ethyl alcohol, concentration is stored in the second ethyl alcohol holding vessel between 30~50% ethyl alcohol；
The heating tank is stainless cylinder of steel, and is equipped with temperature sensor in the tank inner sidewall of the heating tank, is added described
The bottom part down of hot tank is equipped with primary heater, the liquid out that the condenser is built-in with the condenser pipe of both ends exposing and bottom end is exposed
Pipe, the adsorption plant include sequentially connected sealing cover, vertical pipe and liquid collecting funnel from top to bottom, wherein the condenser pipe
It is formed by connecting side by side by several v-shaped tubes, and the bottom end of each v-shaped tube is made to be connected to the top of the outlet tube, the sealing cover
In back-off funnel-form, large pore resin absorption column is filled in the pipe of the vertical pipe；
The discharge port of the crusher is connected to the feed inlet of the grinding mill, and the discharge port of the grinding mill is connected to the electricity
One end of dynamic gate valve, the other end of the electric gate valve are connected to the feed inlet of the heating tank, the feed liquor of first metering pump
End is connected to bottom in the tank of the first ethyl alcohol holding vessel, and the outlet end of first metering pump is connected to the feed liquor of the heating tank
Mouthful, the tank inner top of the heating tank is connected to one end of the condenser pipe, and the other end of the condenser pipe is connected to the heating tank
Tank in bottom, the bottom end of the outlet tube is connected to the inlet of the extracting solution holding vessel, the feed liquor of second metering pump
End is connected to bottom in the tank of the extracting solution holding vessel, and the outlet end connection described two into one of second metering pump goes out type threeway
First input end of solenoid valve, the liquid feeding end of the third metering pump are connected to bottom in the tank of the second ethyl alcohol holding vessel, institute
The outlet end for stating third metering pump is connected to described two into one the second input ends for going out type three-way magnetic valve, and described two into one go out type three
The outlet end of three-way electromagnetic valve is connected to the inside of the sealing cover, and the bottom port of the liquid collecting funnel is connected to the one-in-and-two-out type
The input end of three-way magnetic valve, the first exit end of the one-in-and-two-out type three-way magnetic valve are connected to the extracting solution holding vessel
Inlet, the second outlet end of the one-in-and-two-out type three-way magnetic valve are connected to the eluent holding vessel, the 4th metering
The liquid feeding end of pump is connected to bottom in the tank of the eluent holding vessel, and the outlet end of the 4th metering pump is connected to the concentration knot
The inlet of brilliant equipment；
The output end of the temperature sensor communicates to connect the input terminal of the industrial personal computer, the output end point of the industrial personal computer
The crusher, the grinding mill, the electric gate valve, the primary heater, first metering pump, institute are not communicated to connect
State the second metering pump, the third metering pump, the 4th metering pump, described two into one go out type three-way magnetic valve, described one into
Two go out the controlled end of type three-way magnetic valve and the condensing crystallizing equipment.
Optimization, further include acid liquor storage tank, the 5th metering pump and pH value sensor, wherein the pH value sensor is set
It sets on the tank inner sidewall of the extracting solution holding vessel；
The liquid feeding end of 5th metering pump is connected to bottom in the tank of the acid liquor storage tank, and the 5th metering pump goes out
Liquid end is connected to bottom in the tank of the extracting solution holding vessel, and the output end of the pH value sensor communicates to connect the industrial personal computer
Input terminal, the output end of the industrial personal computer communicate to connect the controlled end of the 5th metering pump.
Optimization, the extracting solution holding vessel is stainless cylinder of steel, and is equipped in the tank inner sidewall of the extracting solution holding vessel
Strength of fluid sensor is equipped with secondary heater in the bottom part down of the extracting solution holding vessel, wherein the strength of fluid passes
The output end of sensor communicates to connect the input terminal of the industrial personal computer, the output end communication connection of the industrial personal computer second heating
The controlled end of device.
Optimization, the outlet end that connection described two into one goes out type three-way magnetic valve is equipped in the lid internal upper part of the sealing cover
Spray head.
Optimization, the top port of the vertical pipe is threadedly engaged with the bottom port of the sealing cover and connect, described perpendicular
The bottom port of straight tube is threadedly engaged with the top port of the liquid collecting funnel and connect.
Optimization, bottom is fixed with downward projection of dome-type sieve in the pipe of the vertical pipe.
Specifically, the crusher is roller crusher.
Specifically, the grinding mill is spherical grinding mill.
Specifically, the condenser pipe and/or the outlet tube are made of stainless steel material.
Specifically, the industrial personal computer uses PLC control system.
The utility model has the following beneficial effects:
(1) the invention provide a kind of application industrial personal computer be controlled automatically at extract it is each in polymethoxyflavone technique
The novel device of processing links can be automatically performed comprising dried immature fruit of citron orange crushing, effective component refluxing extraction, adsorption and desorption and concentration
The complete process flow of crystallization etc., and it is whole without artificial participation, so as to greatly promote the degree of automation of whole device,
Reduce human cost；
It (2), can be according to existing mature work due to applying a large amount of metering pump and related sensor in extraction element
Process accurately controls the dosing and environmental parameter of each processing links, and by utilizing the efficient of macroporous absorbent resin
Absorption feature, it can be ensured that the high efficiency that drug ingredient extracts promotes the utilization rate of the dried immature fruit of citron orange and the production of final polymethoxyflavone
Amount；
(3) described device has many advantages, such as convenient disassembly, also conducive to clearing up and being easily achieved, convenient for actually promoting and answering
With.
Detailed description of the invention
In order to illustrate the embodiment of the utility model or the technical proposal in the existing technology more clearly, below will be to embodiment
Or attached drawing needed to be used in the description of the prior art is briefly described, it should be apparent that, the accompanying drawings in the following description is only
It is some embodiments of the utility model, for those of ordinary skill in the art, in the premise not made the creative labor
Under, it is also possible to obtain other drawings based on these drawings.
Fig. 1 is provided by the utility model for extracting the apparatus structure schematic diagram of polymethoxyflavone in the dried immature fruit of citron orange.
In above-mentioned attached drawing: 1- crusher；2- grinding mill；3- electric gate valve；4- heating tank；401- temperature sensor；402-
Primary heater；5- the first ethyl alcohol holding vessel；The first metering pump of 601-；The second metering pump of 602-；603- third metering pump；604-
4th metering pump；The 5th metering pump of 605-；7- condenser；701- condenser pipe；702- outlet tube；8- extracting solution holding vessel；801-
Strength of fluid sensor；802- secondary heater；9- the second ethyl alcohol holding vessel；10- bis- goes out type three-way magnetic valve into one；11- inhales
Applying equipment；1101- sealing cover；1102- vertical pipe；1103- liquid collecting funnel；1104- large pore resin absorption column；1105- spray head；
1106- dome-type sieve；12- one-in-and-two-out type three-way magnetic valve；13- eluent holding vessel；14- condensing crystallizing equipment；15- work
Control machine；16- acid liquor storage tank；17-PH value sensor.
Specific embodiment
With reference to the accompanying drawing and specific embodiment is further elaborated the utility model.It should be noted that right
It is used to help understand the utility model in the explanation of these way of example, but does not constitute the restriction to the utility model.
The terms "and/or", only a kind of incidence relation for describing affiliated partner, indicates that there may be three kinds of passes
System, for example, A and/or B, can indicate: individualism A, individualism B exist simultaneously tri- kinds of situations of A and B, the terms
"/and " it is to describe another affiliated partner relationship, indicate may exist two kinds of relationships, for example, A/ and B, can indicate: individually depositing
In A, two kinds of situations of individualism A and B, in addition, character "/" herein, typicallying represent forward-backward correlation object is a kind of "or" pass
System.
Embodiment one
As shown in Figure 1, the device for extraction polymethoxyflavone in the dried immature fruit of citron orange provided in this embodiment, including it is broken
Machine 1, grinding mill 2, electric gate valve 3, heating tank 4, the first ethyl alcohol holding vessel 5, the first metering pump 601, condenser 7, extracting solution storage
It deposits tank 8, the second ethyl alcohol holding vessel 9, the second metering pump 602, third metering pump 603, two and goes out type three-way magnetic valve 10, absorption into one
Equipment 11, one-in-and-two-out type three-way magnetic valve 12, eluent holding vessel 13, the 4th metering pump 604, condensing crystallizing equipment 14 and work
Control machine 15, wherein concentration is stored in the first ethyl alcohol holding vessel 5 between 60~80% ethyl alcohol, in second second
Concentration is stored in alcohol holding vessel 9 between 30~50% ethyl alcohol.
The heating tank 4 is stainless cylinder of steel, and is equipped with temperature sensor 401 in the tank inner sidewall of the heating tank 4, in institute
The bottom part down for stating heating tank 4 is equipped with primary heater 402, and the condenser 7 is built-in with condenser pipe 701 and the bottom of both ends exposing
The outlet tube 702 exposed is held, the adsorption plant 11 includes sequentially connected sealing cover 1101,1102 and of vertical pipe from top to bottom
Liquid collecting funnel 1103, wherein the condenser pipe 701 is formed by connecting side by side by several v-shaped tubes, and makes the bottom end of each v-shaped tube
It is connected to the top of the outlet tube 702, the sealing cover 1101 is filled in the pipe of the vertical pipe 1102 in funnel-form is buckled to
Large pore resin absorption column 1104.
The discharge port of the crusher 1 is connected to the feed inlet of the grinding mill 2, and the discharge port of the grinding mill 2 is connected to institute
One end of electric gate valve 3 is stated, the other end of the electric gate valve 3 is connected to the feed inlet of the heating tank 4, first metering pump
601 liquid feeding end is connected to bottom in the tank of the first ethyl alcohol holding vessel 5, and the outlet end of first metering pump 601 is connected to institute
The inlet of heating tank 4 is stated, the tank inner top of the heating tank 4 is connected to one end of the condenser pipe 701, the condenser pipe 701
The other end be connected to bottom in the tank of the heating tank 4, the bottom end of the outlet tube 702 is connected to the extracting solution holding vessel 8
Inlet, the liquid feeding end of second metering pump 602 are connected to bottom in the tank of the extracting solution holding vessel 8, second metering
Pump 602 outlet end be connected to described two into one go out type three-way magnetic valve 10 the first input ends, the third metering pump 603 into
Liquid end is connected to bottom in the tank of the second ethyl alcohol holding vessel 9, the outlet end connection described two into one of the third metering pump 603
Second input end of type three-way magnetic valve 10 out, described two into one outlet ends for going out type three-way magnetic valve 10 are connected to the sealing cover
1101 inside, the bottom port of the liquid collecting funnel 1103 are connected to the input end of the one-in-and-two-out type three-way magnetic valve 12,
The first exit end of the one-in-and-two-out type three-way magnetic valve 12 is connected to the inlet of the extracting solution holding vessel 8, described one into
The two second outlet ends for going out type three-way magnetic valve 12 are connected to the eluent holding vessel 13, the feed liquor of the 4th metering pump 604
End is connected to bottom in the tank of the eluent holding vessel 13, and the outlet end of the 4th metering pump 604 is connected to the condensing crystallizing
The inlet of equipment 14.
The output end of the temperature sensor 401 communicates to connect the input terminal of the industrial personal computer 15, the industrial personal computer 15
Output end communicates to connect the crusher 1, the grinding mill 2, the electric gate valve 3, the primary heater 402, institute respectively
State the first metering pump 601, second metering pump 602, the third metering pump 603, the 4th metering pump 604, described two
The controlled end for going out type three-way magnetic valve 10, the one-in-and-two-out type three-way magnetic valve 12 and the condensing crystallizing equipment 14 into one.
As shown in Figure 1, the crusher 1 is used in the apparatus structure for extracting polymethoxyflavone in the dried immature fruit of citron orange
Under the start-up and shut-down control in the industrial personal computer 15, the dried immature fruit of citron orange block of feeding is crushed, can be, but not limited to break for drum-type
Broken machine.The grinding mill 2 is used under the start-up and shut-down control of the industrial personal computer 15, carries out further powder to broken dried immature fruit of citron orange fragment
Breakdown mill, to obtain the smaller Immature Orange Fruit of granularity, and then during subsequent refluxing extraction, it is possible to increase Immature Orange Fruit
With the contact area of extractant, conducive to fully effective component of chinese medicine is extracted from the dried immature fruit of citron orange, can be, but not limited to for
Spherical grinding mill.The electric gate valve 3 be used under the control of the industrial personal computer 15, close or be connected the heating tank 4 into
Material mouth, during refluxing extraction, to prevent the mixed gas evaporated from escaping from the feed inlet.By aforementioned crusher 1,
Grinding mill 2, electric gate valve 3 and the industrial personal computer 15, that is, may make up has the characteristics that the dried immature fruit of citron orange of automation crushes feeding mechanism.
The heating tank 4 be used to provide using extractant (i.e. concentration between 60~80% ethyl alcohol) seep and steep Immature Orange Fruit
Container place, to extract the Chinese medicine comprising polymethoxyflavone, volatile oil substance and alkaloid etc. from Immature Orange Fruit
Effective component (extracting method is existing method), while can provide heating method and accelerating extraction rate, and evaporating generation and include
The mixed gas of polymethoxyflavone, volatile oil substance, alkaloid and ethyl alcohol etc., wherein the temperature sensor 401 is used for
The temperature data of pot liquid is acquired, to be sent to the industrial personal computer 15, realizes the heating for controlling the primary heater 401
Power purpose makes pot liquid be in one always most useful in the temperature environment extracted and evaporated.The first ethyl alcohol storage
Tank 5 is for storing as extractant and concentration between 60~80% ethyl alcohol.First metering pump 601 is used in the work
Under the control of control machine 15, accurate control import the heating tank 4 extractant dosage (i.e. concentration between 60~80% ethyl alcohol,
Its weight ratio with Immature Orange Fruit is generally in 1:0.1 or so).The condenser 7 is located in the condenser pipe 701 for cooling
Mixed gas obtains the extracting solution comprising polymethoxyflavone, volatile oil substance, alkaloid and ethyl alcohol etc. to condense, wherein
In order to improve heat exchange cooling efficiency, the condenser pipe 701 and/or the outlet tube 702 are preferably made of stainless steel material.Simultaneously
Since the condenser pipe 701 is designed using more v-shaped tubes, and the top of the outlet tube 702 is made to be connected to the bottom end of each v-shaped tube,
So that the bottom end of the outlet tube 702 is connected to the inlet of the extracting solution holding vessel 8, cooling can be condensed and be mentioned described in obtaining
Liquid is taken to import in the extracting solution holding vessel 8.Further, since the other end of the condenser pipe 701 is connected to the tank of the heating tank 4
Interior bottom can lead back to the mixed gas of uncolled condensation in the heating tank 4 again, realize refluxing extraction purpose.Thus lead to
Cross aforementioned heating tank 4, the first ethyl alcohol holding vessel 5, the first metering pump 601, condenser 7, extracting solution holding vessel 8 and the industrial personal computer
15, that is, it may make up the Chinese medicine refluxing extraction mechanism with automation.
The extracting solution holding vessel 8 is for storing to be adsorbed and including polymethoxyflavone, volatile oil substance, biology
The extracting solution of alkali and ethyl alcohol etc..Second metering pump 602 is used under the control of the industrial personal computer 15, and accurate control imports institute
State the extracting solution dosage and flow velocity of adsorption plant 11.The second ethyl alcohol holding vessel 9 is for storing as eluant, eluent and concentration
Between 30~50% ethyl alcohol.The third metering pump 603 is used under the control of the industrial personal computer 15, and accurate control imports institute
State the eluent dosage and flow velocity of adsorption plant 11.Described two into one, which go out type three-way magnetic valve 10, is used in the industrial personal computer 15
Under control, the absorbing process stage make its first input end be connected with outlet end and its second input end cut-off, to ensure at this time
Extracting solution be able to enter the adsorption plant 11, and eluant, eluent cannot；The elution processes stage make its second input end with
Outlet end conducting and the cut-off of its first input end, to ensure that eluant, eluent at this time is able to enter the adsorption plant 11, and are extracted
Liquid but cannot.The adsorption plant 11 is for realizing separating process after the first absorption of polymethoxyflavone, wherein the macropore is inhaled
Attached resin column 1104 is used for when permeating extracting solution, is made comprising in polymethoxyflavone, volatile oil substance and alkaloid etc.
Pharmaceutically active ingredient can be adsorbed on macroporous absorbent resin (i.e. a kind of polymer adsorption tree for being free of cation exchange groups and having macroporous structure
Rouge has good macroreticular structure and biggish specific surface area, can be optionally through in physical absorption aqueous solution
Organic matter is the novel organic polymer adsorbent to grow up the 1960s, in environmental protection, food, medicine and other fields
It is widely used) on, and when permeating eluant, eluent, so that the polymethoxyflavone formerly adsorbed is come into full contact with eluant, eluent simultaneously
It oozes out together, realizes the accurate purpose for extracting polymethoxyflavone；The liquid collecting funnel 1103 is for collecting in absorbing process rank
Residual extracting solution when section and at the elution processes stage and eluent comprising polymethoxyflavone and ethyl alcohol.Described one into
Two, which go out type three-way magnetic valve 10, is used under the control of the industrial personal computer 15, goes out its input end with first in the absorbing process stage
The conducting of mouth end and the cut-off of its second outlet end, to ensure that residual extracting solution at this time can be back to the extracting solution holding vessel 8；
The elution processes stage make its input end be connected with second outlet end and its first exit end cut-off, to ensure eluent at this time
The eluent holding vessel 13 can be imported to be stored.From there through aforementioned extracting solution holding vessel 8, the second ethyl alcohol holding vessel 9,
Second metering pump 602, third metering pump 603, two go out type three-way magnetic valve 10, adsorption plant 11, one-in-and-two-out type threeway into one
Solenoid valve 12, eluent holding vessel 13 and the industrial personal computer 15, that is, may make up has the characteristics that first adsorbing for automation elutes afterwards
Polymethoxyflavone extraction mechanism.
The eluent holding vessel 13 be used for store crystallization to be concentrated and include the elution of polymethoxyflavone and ethyl alcohol
Liquid.4th metering pump 604 is used under the control of the industrial personal computer 15, and accurate control imports the condensing crystallizing every time and sets
Standby 14 eluent dosage.The condensing crystallizing equipment 14 is used to carry out condensing crystallizing to eluent, obtains in the more of crystalline solid
Methoxy flavone powder can be realized using existing Conventional concentration crystallizer, such as be can be used in the prior art
The Chinese medical extract concentration and crystallization device being previously mentioned in CN206980125U.The industrial personal computer 15 is for realizing aforementioned each processing
The automatic control purpose of link, relevant control program can refer to that existing control program is write and debugging obtains, in addition,
The industrial personal computer 15 can be, but not limited to using PLC (Programmable Logic Controller, Programmable logical controller
Device aims at a kind of electronic device of digital operation of industrial production design) control system.It is stored up from there through aforementioned eluent
Tank 13, the 4th metering pump 604, condensing crystallizing equipment 14 and the industrial personal computer 15 are deposited, that is, may make up has the characteristics that the dense of automation
The preparing mechanism of sheepshank crystalline substance polymethoxyflavone.
From there through aforementioned device detailed construction describe, on the one hand can be automatically performed comprising the dried immature fruit of citron orange crush, effectively at
Divide the complete process flow of refluxing extraction, adsorption and desorption and condensing crystallizing etc., and whole without artificial participation, so as to big
Big the degree of automation for promoting whole device, reduces human cost；On the other hand, a large amount of due to being applied in extraction element
Metering pump and related sensor, can be accurately controlled according to existing mature technology method each processing links dosing and
Environmental parameter, and the efficient absorption feature by utilizing macroporous absorbent resin, it can be ensured that the high efficiency that drug ingredient extracts mentions
The utilization rate of the dried immature fruit of citron orange and the yield of final polymethoxyflavone are risen, to be conducive to reduce drug market price, promotes health care
The tremendous development of cause.
Optimization, further include acid liquor storage tank 16, the 5th metering pump 605 and pH value sensor 17, wherein the pH value passes
Sensor 17 is arranged on the tank inner sidewall of the extracting solution holding vessel 8；The liquid feeding end of 5th metering pump 605 is connected to the acid
The outlet end of bottom in the tank of liquid holding vessel 16, the 5th metering pump 605 is connected to bottom in the tank of the extracting solution holding vessel 8
Portion, the output end of the pH value sensor 17 communicate to connect the input terminal of the industrial personal computer 15, the output end of the industrial personal computer 15
Communicate to connect the controlled end of the 5th metering pump 605.As shown in Figure 1, the acid liquor storage tank 16 realizes extraction for storing
The acid solution of liquid pH value adjustment, such as hydrochloric acid solution.5th metering pump 605 is used under the control of the industrial personal computer 15, essence
Really control imports the acid solution dosage of the extracting solution holding vessel 8.The pH value sensor 17 is used to acquire the PH of extracting solution in tank
Value Data realizes that controlling the 5th metering pump 605 adds appropriate acid solution, makes to mention in tank to be sent to the industrial personal computer 15
Liquid is taken to be in a state most useful for subsequent adsorbtion always, need to generally adjust pH value is 4~5 or so.From there through aforementioned acid
Liquid holding vessel 16, the 5th metering pump 605 and pH value sensor 17 and the industrial personal computer 15, that is, may make up has the characteristics that automation
Extracting solution is acidified regulating mechanism.
Optimization, the extracting solution holding vessel 8 is stainless cylinder of steel, and is set in the tank inner sidewall of the extracting solution holding vessel 8
There is strength of fluid sensor 801, is equipped with secondary heater 802 in the bottom part down of the extracting solution holding vessel 8, wherein described
The output end of strength of fluid sensor 801 communicates to connect the input terminal of the industrial personal computer 15, and the output end of the industrial personal computer 15 is logical
Letter connects the controlled end of the secondary heater 802.As shown in Figure 1, the strength of fluid sensor 801 is mentioned for acquiring in tank
The concentration data of liquid is taken, to be sent to the industrial personal computer 15, realizes that controlling the secondary heater 802 is heated, and is treated
The extracting solution of absorption carries out the purpose of initial concentration, and extracting solution in tank is made to be in a state most useful for subsequent adsorbtion always,
It is 30~35% or so that concentration, which need to generally be adjusted,.
Optimization, connection described two into one, which is equipped with, in the lid internal upper part of the sealing cover 1101 goes out type three-way magnetic valve 10
The spray head 1105 of outlet end.As shown in Figure 1, passing through previous designs, it can be ensured that extracting solution or eluant, eluent are uniformly sprinkled upon described
The purpose for making full use of everywhere macroporous absorbent resin is realized in the upper surface of large pore resin absorption column 1104.
Optimization, the bottom port of the top port of the vertical pipe 1102 and the sealing cover 1101 is threadedly engaged company
It connects, the bottom port of the vertical pipe 1102 is threadedly engaged with the top port of the liquid collecting funnel 1103 and connect.By aforementioned
Design can be convenient disassembly or the assembling adsorption plant 11, be conducive to replacement macroporous absorbent resin.
Optimization, bottom is fixed with downward projection of dome-type sieve 1106 in the pipe of the vertical pipe 1102.Such as Fig. 1 institute
Show, by designing the dome-type sieve 1106, not only can effectively support the large pore resin absorption column 1104, can also make
The volume maximization of the large pore resin absorption column 1104 improves the amount of single-trial extraction polymethoxyflavone.
To sum up, using the device for being used in the dried immature fruit of citron orange extract polymethoxyflavone provided by the present embodiment, there is following skill
Art effect:
(1) it present embodiments provides a kind of application industrial personal computer and is controlled automatically at and extract each place in polymethoxyflavone technique
The novel device for managing link can be automatically performed comprising dried immature fruit of citron orange crushing, effective component refluxing extraction, adsorption and desorption and concentration knot
The complete process flow of crystalline substance etc., and it is whole without artificial participation, so as to greatly promote the degree of automation of whole device, drop
Low human cost；
It (2), can be according to existing mature work due to applying a large amount of metering pump and related sensor in extraction element
Process accurately controls the dosing and environmental parameter of each processing links, and by utilizing the efficient of macroporous absorbent resin
Absorption feature, it can be ensured that the high efficiency that drug ingredient extracts promotes the utilization rate of the dried immature fruit of citron orange and the production of final polymethoxyflavone
Amount；
(3) described device has many advantages, such as convenient disassembly, also conducive to clearing up and being easily achieved, convenient for actually promoting and answering
With.
The utility model is not limited to above-mentioned optional embodiment, anyone can obtain under the enlightenment of the utility model
Other various forms of products out.Above-mentioned specific embodiment should not be understood the limitation of the pairs of protection scope of the utility model,
The protection scope of the utility model should be subject to be defined in claims, and specification can be used for explaining that right is wanted
Seek book.
Claims (10)
1. a kind of for extracting the device of polymethoxyflavone in the dried immature fruit of citron orange, it is characterised in that: including crusher (1), grinding mill
(2), electric gate valve (3), heating tank (4), the first ethyl alcohol holding vessel (5), the first metering pump (601), condenser (7), extracting solution
Holding vessel (8), the second ethyl alcohol holding vessel (9), the second metering pump (602), third metering pump (603), two into one go out type three and are powered
Magnet valve (10), adsorption plant (11), one-in-and-two-out type three-way magnetic valve (12), eluent holding vessel (13), the 4th metering pump
(604), condensing crystallizing equipment (14) and industrial personal computer (15), wherein concentration Jie is stored in the first ethyl alcohol holding vessel (5)
In 60~80% ethyl alcohol, concentration is stored between 30~50% ethyl alcohol in the second ethyl alcohol holding vessel (9)；
The heating tank (4) is stainless cylinder of steel, and is equipped with temperature sensor (401) in the tank inner sidewall of the heating tank (4),
The bottom part down of the heating tank (4) is equipped with primary heater (402), and the condenser (7) is built-in with the condensation of both ends exposing
The outlet tube (702) that (701) and bottom end are exposed is managed, the adsorption plant (11) includes sequentially connected sealing cover from top to bottom
(1101), vertical pipe (1102) and liquid collecting funnel (1103), wherein the condenser pipe (701) is connected side by side by several v-shaped tubes
It forms, and the bottom end of each v-shaped tube is made to be connected to the top of the outlet tube (702), the sealing cover (1101) is in back-off funnel
Shape, the pipe of the vertical pipe (1102) is interior to be filled with large pore resin absorption column (1104)；
The discharge port of the crusher (1) is connected to the feed inlet of the grinding mill (2), the discharge port connection of the grinding mill (2)
One end of the electric gate valve (3), the other end of the electric gate valve (3) are connected to the feed inlet of the heating tank (4), and described the
The liquid feeding end of one metering pump (601) is connected to bottom in the tank of the first ethyl alcohol holding vessel (5), first metering pump (601)
Outlet end be connected to the inlet of the heating tank (4), the tank inner top of the heating tank (4) is connected to the condenser pipe (701)
One end, the other end of the condenser pipe (701) is connected to bottom in the tank of the heating tank (4), the bottom of the outlet tube (702)
End is connected to the inlet of the extracting solution holding vessel (8), and the liquid feeding end of second metering pump (602) is connected to the extracting solution storage
Bottom in the tank of tank (8) is deposited, the outlet end connection described two into one of second metering pump (602) goes out type three-way magnetic valve (10)
The first input end, the liquid feeding end of the third metering pump (603) is connected to bottom in the tank of the second ethyl alcohol holding vessel (9),
The outlet end of the third metering pump (603) is connected to described two into one the second input ends for going out type three-way magnetic valve (10), described
Two into one outlet ends for going out type three-way magnetic valve (10) are connected to the inside of the sealing cover (1101), the liquid collecting funnel (1103)
Bottom port be connected to the input end of the one-in-and-two-out type three-way magnetic valve (12), the one-in-and-two-out type three-way magnetic valve
(12) first exit end is connected to the inlet of the extracting solution holding vessel (8), the one-in-and-two-out type three-way magnetic valve (12)
Second outlet end be connected to the eluent holding vessel (13), the liquid feeding end of the 4th metering pump (604) is connected to the elution
The outlet end of bottom in the tank of liquid holding vessel (13), the 4th metering pump (604) is connected to the condensing crystallizing equipment (14)
Inlet；
The output end of the temperature sensor (401) communicates to connect the input terminal of the industrial personal computer (15), the industrial personal computer (15)
Output end communicate to connect respectively the crusher (1), the grinding mill (2), the electric gate valve (3), it is described first heating
Device (402), first metering pump (601), second metering pump (602), the third metering pump (603), the described 4th
Metering pump (604), described two into one go out type three-way magnetic valve (10), the one-in-and-two-out type three-way magnetic valve (12) and described dense
The controlled end of contracting crystallizer (14).
2. as described in claim 1 a kind of for extracting the device of polymethoxyflavone in the dried immature fruit of citron orange, it is characterised in that: further include
Acid liquor storage tank (16), the 5th metering pump (605) and pH value sensor (17), wherein pH value sensor (17) setting exists
On the tank inner sidewall of the extracting solution holding vessel (8)；
The liquid feeding end of 5th metering pump (605) is connected to bottom in the tank of the acid liquor storage tank (16), the 5th metering
The outlet end for pumping (605) is connected to bottom in the tank of the extracting solution holding vessel (8), and the output end of the pH value sensor (17) is logical
Letter connects the input terminal of the industrial personal computer (15), and the output end of the industrial personal computer (15) communicates to connect the 5th metering pump
(605) controlled end.
3. as described in claim 1 a kind of for extracting the device of polymethoxyflavone in the dried immature fruit of citron orange, it is characterised in that: described to mention
Taking liquid holding vessel (8) is stainless cylinder of steel, and is equipped with strength of fluid sensor in the tank inner sidewall of the extracting solution holding vessel (8)
(801), secondary heater (802) are equipped in the bottom part down of the extracting solution holding vessel (8), wherein the strength of fluid passes
The output end of sensor (801) communicates to connect the input terminal of the industrial personal computer (15), the output end communication link of the industrial personal computer (15)
Connect the controlled end of the secondary heater (802).
4. as described in claim 1 a kind of for extracting the device of polymethoxyflavone in the dried immature fruit of citron orange, it is characterised in that: described
The lid internal upper part of sealing cover (1101) is equipped with the spray head that connection described two into one goes out the outlet end of type three-way magnetic valve (10)
(1105)。
5. as described in claim 1 a kind of for extracting the device of polymethoxyflavone in the dried immature fruit of citron orange, it is characterised in that: described perpendicular
The top port of straight tube (1102) is threadedly engaged with the bottom port of the sealing cover (1101) and connect, the vertical pipe (1102)
Bottom port be threadedly engaged and connect with the top port of the liquid collecting funnel (1103).
6. as described in claim 1 a kind of for extracting the device of polymethoxyflavone in the dried immature fruit of citron orange, it is characterised in that: described perpendicular
Bottom is fixed with downward projection of dome-type sieve (1106) in the pipe of straight tube (1102).
7. as described in claim 1 a kind of for extracting the device of polymethoxyflavone in the dried immature fruit of citron orange, it is characterised in that: described broken
Broken machine (1) is roller crusher.
8. as described in claim 1 a kind of for extracting the device of polymethoxyflavone in the dried immature fruit of citron orange, it is characterised in that: the stone roller
Grinding machine (2) is spherical grinding mill.
9. as described in claim 1 a kind of for extracting the device of polymethoxyflavone in the dried immature fruit of citron orange, it is characterised in that: described cold
Solidifying pipe (701) and/or the outlet tube (702) are made of stainless steel material.
10. as described in claim 1 a kind of for extracting the device of polymethoxyflavone in the dried immature fruit of citron orange, it is characterised in that: described
Industrial personal computer (15) uses PLC control system.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820991174.2U CN208893220U (en) | 2018-06-26 | 2018-06-26 | A kind of device for extraction polymethoxyflavone in the dried immature fruit of citron orange |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820991174.2U CN208893220U (en) | 2018-06-26 | 2018-06-26 | A kind of device for extraction polymethoxyflavone in the dried immature fruit of citron orange |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN208893220U true CN208893220U (en) | 2019-05-24 |
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ID=66566965
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201820991174.2U Active CN208893220U (en) | 2018-06-26 | 2018-06-26 | A kind of device for extraction polymethoxyflavone in the dried immature fruit of citron orange |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN208893220U (en) |
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2018
- 2018-06-26 CN CN201820991174.2U patent/CN208893220U/en active Active
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Effective date of registration: 20201103 Address after: 618400 Deyang City, Sichuan province Shifang City nine Li Geng Cun town Division Patentee after: Sichuan aimailang Biotechnology Co., Ltd Address before: Kyrgyzstan Ruisan road 610000 Sichuan city of Chengdu province high tech Zone 99 No. 1 building 4 unit 15 Floor No. 1501 Patentee before: SICHUAN YUNYICHUN TECHNOLOGY Co.,Ltd. |