CN208877295U - A kind of three chamber infusion bags for long chain fat emulsion, amino acid and compound glucose electrolyte injection in packing - Google Patents
A kind of three chamber infusion bags for long chain fat emulsion, amino acid and compound glucose electrolyte injection in packing Download PDFInfo
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- CN208877295U CN208877295U CN201720833177.9U CN201720833177U CN208877295U CN 208877295 U CN208877295 U CN 208877295U CN 201720833177 U CN201720833177 U CN 201720833177U CN 208877295 U CN208877295 U CN 208877295U
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Abstract
The utility model discloses a kind of three chamber infusion bags for long chain fat emulsion, amino acid and compound glucose electrolyte injection in packing, including infusion bag ontology, the infusion bag ontology is divided into first chamber, second chamber and third chamber by weak welding rod；Infusion bag ontology two sides cover Packed barrier film, are provided with oxygen absorbent between infusion bag ontology and the barrier film.The barrier property of infusion bag and oxygen can be improved in the utility model, improves the antioxidant capacity of infusion bag, extends the pot-life of medicament.
Description
Technical field
The utility model relates to a kind of three chamber parenteral nutritions infusion products.
Background technique
Parenteral nutrition is the nutritional support mode of whole nutritional factors needed for supplying patient by intravenous route, makes patient
A kind for the treatment of method of good nutrition state is maintained in the case where not feeding, Parenteral Nutrition Treatment is sought to inpatient
Support one of the important means of support.Fat, protein and sugar are the maximum three classes basic nutrients of human body requirements amount.In human body
Gastrointestinal function not all or none method meet absorb enough above-mentioned nutriments when, need to provide in a manner of venous transfusion.
Clinically, usually using mixing duct by fat emulsion injection, Amino Acid Compound Injection and compound using preceding
Glucose injection pours into a specially designed aseptic plastic bag, then inputs human body by the infusion port of this bag.Mixing behaviour
Make there are biggish security risk, need that there are four the mixing tubes of syringe needle using a band in use, wherein three mixing tubes are logical
Syringe needle is crossed across each drug rubber plug, inserts into the liquid, another syringe needle insertion mixed bag, by conduit by three medical fluids in mixed bag
Mixing.The process is manual operations, repeatedly punctures the sealing for destroying product, it is easy to the pollution of microorganism is caused to product.
Simultaneously as repeatedly puncturing rubber plug, more rubber plug particle may be generated, into blood after be easy blocking capillary, make
At microcirculation embolism.
Above-mentioned pollution can be lowered by preparing parenteral nutrition infusion product by using instant-matching type multi-chamber liquid liquid infusion bag at present
And embolic risk, it is separated by openable weak welding rod between each chamber liquid drug of multi-chamber-bag, applying pressure to bag body will be weak
Human body is infused to from medical liquid discharge port after welding rod opening mixing.Due to medicament from dispatching from the factory to using with certain period, multicell
Oxygen in infusion bag placement process in air can also penetrate progressively through bag body and enter in bag to react with drug, to influence medicine
The quality of agent.It needs that infusion bag product structure is further improved, to improve its antioxidant capacity, extends the storage life of medicament
Limit.
Utility model content
It is unique that the purpose of the utility model is to provide a kind of structure novels, easy to use, and can be effectively reduced oxygen
Three chamber infusion bags of the middle long chain fat emulsion of infiltration capacity, amino acid and compound glucose electrolyte injection；Particular technique
A kind of scheme are as follows: three Room infusion for long chain fat emulsion, amino acid and compound glucose electrolyte injection in packing
Bag, including infusion bag ontology, the infusion bag ontology are divided into first chamber, second chamber and third chamber by weak welding rod；
Infusion bag ontology two sides cover Packed barrier film, and oxygen absorbent, institute are provided between infusion bag ontology and the barrier film
State infusion bag ontology width and height ratio be 0.7 to 1.0 (such as proportional region 0.7-0.8,0.7-0.9,0.8-0.9,
0.8-1.0), one end of the weak welding rod is provided with stress and concentrates circular arc；Wherein:
(1) first chamber, second chamber and third chamber are packaged with 36% compound glucose electrolyte injection respectively
Liquid, 16 amino acids (16AA) injection and medium and long chain fat emulsion injection, liquid amount are respectively the electrolysis of compound glucose
Matter injection 250ml, 16 amino acids (16AA) injection 250ml and medium and long chain fat emulsion injection 125ml；Or dress
Liquid measure is respectively compound glucose electrolyte injection 500ml, 16 amino acids (16AA) injection 500ml and middle long-chain
Fat emulsion injection 250ml；
(2) first chamber, second chamber and third chamber are packaged with 16% compound glucose electrolyte injection respectively
Liquid, 16 amino acids (16AA) injection and medium and long chain fat emulsion injection, liquid amount are respectively the electrolysis of compound glucose
Matter injection 500ml, 16 amino acids (16AA) injection 500ml and medium and long chain fat emulsion injection 250ml, or dress
Liquid measure is respectively compound glucose electrolyte injection 750ml, 16 amino acids (16AA) injection 750ml and middle long-chain
Fat emulsion injection 375ml；
(3) first chamber, second chamber and third chamber are packaged with 30% compound glucose electrolyte injection respectively
Liquid, 16 amino acids (16AA) injection and medium and long chain fat emulsion injection, liquid amount are respectively the electrolysis of compound glucose
Matter injection 500ml, 16 amino acids (16AA) injection 500ml and medium and long chain fat emulsion injection 250ml, or dress
Liquid measure is respectively compound glucose electrolyte injection 750ml, 16 amino acids (16AA) injection 750ml and middle long-chain
Fat emulsion injection 375ml；
(4) first chamber, second chamber and third chamber are packaged with long chain fat emulsion in ω -3 fish oil respectively and inject
Liquid, 16 amino acids (16AA) injection and 30% compound glucose electrolyte injection, liquid amount are respectively ω -3 fish
Oily medium and long chain fat emulsion injection 250ml, 16 amino acids (16AA) injection 500ml and compound glucose electrolyte note
It penetrates liquid 500ml or liquid amount is respectively ω -3 fish oil medium and long chain fat emulsion injection 375ml, 16 amino acids (16AA)
Injection 750ml and compound glucose electrolyte injection 750ml or liquid amount are respectively long chain fat emulsion in ω -3 fish oil
Injection 500ml, 16 amino acids (16AA) injection 1000ml and compound glucose electrolyte injection 1000ml；Or
(5) first chamber, second chamber and third chamber are packaged with long chain fat emulsion in ω -3 fish oil respectively and inject
Liquid, 16 amino acids (16AA) injection and 36% compound glucose electrolyte injection, liquid amount are respectively ω -3 fish
Oily medium and long chain fat emulsion injection 125ml, 16 amino acids (16AA) injection 250ml and compound glucose electrolyte note
It penetrates liquid 250ml or liquid amount is respectively ω -3 fish oil medium and long chain fat emulsion injection 250ml, 16 amino acids (16AA)
Injection 500ml and compound glucose electrolyte injection 500ml or liquid amount are respectively long chain fat emulsion in ω -3 fish oil
Injection 375ml, 16 amino acids (16AA) injection 750ml and compound glucose electrolyte injection 750ml, or
Liquid amount be respectively ω -3 fish oil medium and long chain fat emulsion injection 500ml, 16 amino acids (16AA) injection 1000ml and
Compound glucose electrolyte injection 1000ml.
On the other hand, the utility model provides a kind of for long chain fat emulsion, 16 amino acid (16AA) and 36% in packing
Three chamber infusion bags of glucose electrolyte injection, including infusion bag ontology, the infusion bag ontology are divided by weak welding rod
First chamber, second chamber and third chamber, the compound glucose injection of filling 250ml, the second chamber in the first chamber
Filling 250ml Amino Acid Compound Injection in room, the medium and long chain fat emulsion injection of filling 125ml, described defeated in third chamber
Liquid bag ontology two sides cover Packed barrier film, are provided with oxygen absorbent between the infusion bag ontology and the barrier film.
The utility model also provides another for long chain fat emulsion, 16 amino acid (16AA) and 36% grape in packing
Three chamber infusion bags of sugared electrolyte injection, including infusion bag ontology, the infusion bag ontology are divided into first by weak welding rod
Chamber, second chamber and third chamber, the compound glucose injection of filling 500ml in the first chamber, in second chamber
Filling 500ml Amino Acid Compound Injection, the medium and long chain fat emulsion injection of filling 250ml, the infusion bag in third chamber
Ontology two sides cover Packed barrier film, are provided with oxygen absorbent between the infusion bag ontology and the barrier film.
On the other hand, it is provided by the utility model it is a kind of for long chain fat emulsion in packing, 16 amino acid (16AA) and
Three chamber infusion bags of 16% glucose electrolyte injection, including infusion bag ontology, the infusion bag ontology pass through weak welding rod point
It is divided into first chamber, second chamber and third chamber, the compound glucose injection of filling 500ml in the first chamber, the
Filling 500ml Amino Acid Compound Injection in two chambers, the medium and long chain fat emulsion injection of filling 250ml, institute in third chamber
It states infusion bag ontology two sides and covers Packed barrier film, be provided with oxygen uptake between the infusion bag ontology and the barrier film
Agent.
It is provided by the utility model another for long chain fat emulsion, 16 amino acid (16AA) and 16% grape in packing
Three chamber infusion bags of sugared electrolyte injection, including infusion bag ontology, the infusion bag ontology are divided into first by weak welding rod
Chamber, second chamber and third chamber, the compound glucose injection of filling 750ml in the first chamber, in second chamber
Filling 750ml Amino Acid Compound Injection, the medium and long chain fat emulsion injection of filling 375ml, the infusion bag in third chamber
Ontology two sides cover Packed barrier film, are provided with oxygen absorbent between the infusion bag ontology and the barrier film.
On the other hand, the utility model provides a kind of for long chain fat emulsion, 16 amino acid (16AA) and 30% in packing
Three chamber infusion bags of glucose electrolyte injection, including infusion bag ontology, the infusion bag ontology are divided by weak welding rod
First chamber, second chamber and third chamber, the compound glucose injection of filling 500ml, the second chamber in the first chamber
Filling 500ml Amino Acid Compound Injection in room, the medium and long chain fat emulsion injection of filling 250ml, described defeated in third chamber
Liquid bag ontology two sides cover Packed barrier film, are provided with oxygen absorbent between the infusion bag ontology and the barrier film.
The utility model also provides a kind of for long chain fat emulsion, 16 amino acid (16AA) and 30% glucose electricity in packing
Solve three chamber infusion bags of matter injection, including infusion bag ontology, the infusion bag ontology by weak welding rod be divided into first chamber,
Second chamber and third chamber, the compound glucose injection of filling 750ml in the first chamber are filling in second chamber
750ml Amino Acid Compound Injection, the medium and long chain fat emulsion injection of filling 375ml, the infusion bag ontology in third chamber
Two sides cover Packed barrier film, are provided with oxygen absorbent between the infusion bag ontology and the barrier film.
On the other hand, the utility model provides long chain fat emulsion, 16 kinds of amino acid (16AA) in a kind of packaging ω -3 fish oil
With the multicell liquid liquid infusion bag of 30% glucose injection, including infusion bag ontology, the infusion bag ontology passes through weak welding rod point
It is divided at least three chambers；Infusion bag ontology two sides cover Packed barrier film；At least three chambers difference
Independent packaging has ω -3 fish oil medium and long chain fat emulsion injection, amino acid injection and glucose injection.
Preferably, the ω -3 fish oil medium and long chain fat emulsion injection, amino acid injection and glucose injection fill liquid
Amount volume ratio is 1:2:2；The volume of each chamber is arranged in a manner of being suitable for accommodate respective liquid amount；Optionally, the ω -3
The liquid amount of fish oil medium and long chain fat emulsion injection is 250ml or 375ml, and the liquid amount of the amino acid injection is 500ml
Or 750ml, the liquid amount of the glucose injection are 500ml or 750ml.Optionally, long-chain fat in ω -3 fish oil
The liquid amount of emulsion injection is 500ml, and the liquid amount of the amino acid injection is 1000ml, the dress of the glucose injection
Liquid measure is 1000ml.
In a preferred embodiment, long chain fat emulsion in a kind of packaging ω -3 fish oil, amino acid and glucose injection
Multicell liquid liquid infusion bag, including infusion bag ontology, if the infusion bag ontology is divided into three chambers by welding rod, described first
It is packaged with the ω -3 fish oil medium and long chain fat emulsion injection of 250ml in chamber, the amino of 500ml is packaged in the second chamber
Acid injection is packaged with the glucose injection of 500ml in the third chamber, and infusion bag ontology two sides are covered with close
The barrier film of envelope.
In a preferred embodiment, long chain fat emulsion in a kind of packaging ω -3 fish oil, amino acid and glucose injection
Multicell liquid liquid infusion bag, including infusion bag ontology, if the infusion bag ontology is divided into three chambers by welding rod, described first
It is packaged with the ω -3 fish oil medium and long chain fat emulsion injection of 375ml in chamber, the amino of 750ml is packaged in the second chamber
Acid injection is packaged with the glucose injection of 750ml in the third chamber, and infusion bag ontology two sides are covered with close
The barrier film of envelope.
On the other hand, the utility model provides long chain fat emulsion, 16 kinds of amino acid (16AA) in a kind of packaging ω -3 fish oil
With the multicell liquid liquid infusion bag of 36% glucose injection, including infusion bag ontology, the infusion bag ontology passes through weak welding rod point
It is divided at least three chambers；Infusion bag ontology two sides cover Packed barrier film；At least three chambers difference
Independent packaging has ω -3 fish oil medium and long chain fat emulsion injection, amino acid injection and glucose injection.
Preferably, the ω -3 fish oil medium and long chain fat emulsion injection, amino acid injection and glucose injection fill liquid
Amount volume ratio is 1:2:2；The volume of each chamber is arranged in a manner of being suitable for accommodate respective liquid amount；Optionally, the ω -3
The liquid amount of fish oil medium and long chain fat emulsion injection is 125ml or 250ml, and the liquid amount of the amino acid injection is 250ml
Or 500ml, the liquid amount of the glucose injection are 250ml or 500ml.
In a preferred embodiment, long chain fat emulsion, 16 kinds of amino acid (16AA) and 36% in a kind of packaging ω -3 fish oil
The multicell liquid liquid infusion bag of glucose injection, including infusion bag ontology, if the infusion bag ontology is divided into three by welding rod
A chamber is packaged with the ω -3 fish oil medium and long chain fat emulsion injection of 125ml in the first chamber, wraps in the second chamber
Amino acid injection equipped with 250ml is packaged with the glucose injection of 250ml, the infusion bag sheet in the third chamber
Body two sides cover Packed barrier film.
In a preferred embodiment, long chain fat emulsion, 16 kinds of amino acid (16AA) and 36% in a kind of packaging ω -3 fish oil
The multicell liquid liquid infusion bag of glucose injection, including infusion bag ontology, if the infusion bag ontology is divided into three by welding rod
A chamber is packaged with the ω -3 fish oil medium and long chain fat emulsion injection of 250ml in the first chamber, wraps in the second chamber
Amino acid injection equipped with 500ml is packaged with the glucose injection of 500ml, the infusion bag sheet in the third chamber
Body two sides cover Packed barrier film.
In preferred embodiments, suction is provided between infusion bag ontology described in the utility model and the barrier film
Oxygen agent.
Further, the oxygen absorbent is bulk, and quantity is 1 piece or muti-piece.
Further, the oxygen absorbent can be plane coating, stripe coating or netted coating.
Further, the oxygen absorbent can be one or more independent oxygen absorbent packagings.
Further, the oxygen uptake ability of the oxygen absorbent is not less than 100ml, is preferably not less than 200ml.
Further, the oxygen transit dose of the barrier film is not more than 1.0cm3/(m2Its 0.1MPa).
Wherein, oxygen transit dose cm3/(m2Its 0.1MPa) refer under 0.1MPa (atmospheric pressure) pressure differential, often put down
The volume for the gas that the barrier film of square rice is penetrated daily.
On the other hand, for need to avoid weak welding rod open by mistake open and need guarantee use when be easy open between there are lances
This problem of shield concentrates circular arc using in the same side setting stress；It is the arc-shaped that corner is arched upward inwardly that stress, which concentrates circular arc,
Weak welding rod concentrates circular arc to make that stress point is concentrated on cambered one end in artificial open, guarantees appropriate increase by stress
Still the weld strength that the weak welding rod opened, and increased is easy when using after the weld strength of weak welding rod can with maximum probability
Opening by mistake for weak welding rod is avoided to open.
Further, the same end of the weak welding rod have unidirectional circular arc radian, described one end be weak welding rod with it is defeated
One end of liquid bag ontology connection, described one end is preferably one end of liquid feeding mouth.
Further, the arc radius is 5mm between 23mm, preferably 8mm-20mm, such as 8mm, 10mm, 12mm,
15mm, 16mm, 18mm, 20mm.
Further, the weld strength of the weak welding rod is 5N/15mm-12N/15mm, preferably 7N/15mm-10N/
15mm, such as 7N/15mm, 8N/15mm, 8.5N/15mm, 9N/15mm, 9.5N/15mm, 10N/15mm.
Further, in order to improve medication accuracy and bag stability, the liquid after reducing infusion is remained, the utility model
The height of infusion bag ontology described in the multi-chamber-bag of offer is not less than width.
It is further preferred that the width of the infusion bag ontology and the ratio of height are 0.7-1.0, such as 0.7,0.8,
0.9,1.0。
Further, any one or more in the liquid feeding mouth of the two sides of the bottom of infusion bag ontology are arranged far from this chamber
Middle position, and as medical liquid discharge port, preferably as far as possible with the ipsilateral real welding rod in the short transverse of infusion bag ontology
Close, for example including integrally formed mode, i.e., any one or more in the liquid feeding mouth of infusion bag body bottom portion two sides are with one
Body formed mode is arranged far from the middle position of this chamber；Preferably, the liquid feeding mouth is as medical liquid discharge port, as far as possible
It is close with the ipsilateral real welding rod in the short transverse of infusion bag ontology.
The integrally formed mode includes that liquid feeding mouth is arranged in the welding of mouth pipe on the body simultaneously in ontology preparation
Position makes a mouthful Guan Yuben body by integral forming.
In a preferred embodiment, the infusion bag ontology of the utility model is multi-layer compound structure with film, mainly by changing
Property polypropylene be made, the modified polypropylene material can be selected from the known in the art or high safety that is prepared by a conventional method
Property composite material, such as three-layer co-extruded material, optionally, the infusion bag ontology of the utility model is divided into three layers from the inside to the outside,
Middle internal layer is made of polypropylene material, and middle layer is made of polypropylene, polyethylene, the mixing of styrene-ethylene-butadiene copolymer, outside
Layer is made of polypropylene, the mixing of styrene-ethylene-butadiene copolymer；Optionally, the infusion bag ontology membrane material internal layer is by poly- third
Alkene copolymer, hydrogenated styrene block copolymers, ethylene hydroxy acid ester copolymer composition, middle layer is by polypropylene copolymer, hydrogenation of benzene
Ethylene block copolymer composition, outer layer is by polypropylene copolymer, hydrogenated styrene block copolymers composition.
In the utility model amino acid or Amino Acid Compound Injection refer to the compound be made of a variety of amino acid or
Compound injection, such as 16 kinds of amino acid injections (16AA).16 kinds of amino acid (16AA), 16 amino acid in the utility model
(16AA), 16 kinds of amino acids (16AA), 16 amino acids (16AA) and 16 kinds of amino acid injection (16AA) meaning phases
Together.
16 kinds of amino acid injections (16AA) of the utility model packaging are the amino comprising 16 kinds of amino acid and electrolyte
Acid injection, such as include 16 kinds of amino acid, suitable sodium chloride, sodium acetate, potassium acetate, magnesium acetate, calcium chloride, pH adjusting agent
(such as sodium hydroxide and/or citric acid)；16 kinds of amino acid is isoleucine, leucine, lysine or lysine hydrochloride, first
Methyllanthionine, phenylalanine, threonine, tryptophan, valine, arginine, histidine monohydrochloride or histidine, alanine, door winter ammonia
Acid, glutamic acid, glycine, proline and serine.
30% glucose injection of the utility model packaging is that the compound glucose of 30% mass volumn concentration is infused
Penetrate in liquid, such as every 100ml glucose injection includes glucose with glucose H2O counts 33g or in terms of DEXTROSE ANHYDROUS
30g and suitable sodium dihydrogen phosphate, zinc acetate, citric acid；
36% glucose injection of the utility model packaging is that the compound glucose of 36% mass volumn concentration is infused
Penetrate in liquid, such as every 100ml glucose injection includes glucose with glucose H2O counts 39.6g or in terms of DEXTROSE ANHYDROUS
36g glucose and suitable sodium dihydrogen phosphate, zinc acetate, citric acid；
16% glucose injection of the utility model packaging is that the compound glucose of 16% mass volumn concentration is infused
Penetrate in liquid, such as every 100ml glucose injection includes glucose with glucose H2O counts 17.6g or in terms of DEXTROSE ANHYDROUS
16g glucose and suitable sodium dihydrogen phosphate, zinc acetate, citric acid；
The medium and long chain fat emulsion injection of the utility model packaging is in the infusion bag of an exemplary embodiment, Ke Yiwei
Include the fat emulsion injection of medium chain triglyceride, such as includes soybean oil, medium chain triglyceride, enuatrol, lecithin, sweet
Oily and appropriate sodium hydroxide.
Infusion bag of the ω -3 fish oil medium and long chain fat emulsion injection of the utility model packaging in an exemplary embodiment
In, can be includes the fat emulsion injection of omega-fatty acid triglycerides and medium chain triglyceride, such as comprising soybean oil,
Medium chain triglyceride, omega-fatty acid triglycerides, enuatrol, lecithin, glycerol, alpha-tocopherol and sodium hydroxide.
In the utility model, the three of long chain fat emulsion in packaging, amino acid and compound glucose electrolyte injection
In chamber infusion bag, the liquid amount ratio of the middle long chain fat emulsion, amino acid and compound glucose electrolyte injection is 1:
2:2 also may include the liquid amount that other meet aforementioned proportion in addition to above-mentioned specific liquid amount disclosed by the utility model.Institute
The volume for stating each chamber is arranged in a manner of being suitable for accommodate respective liquid amount.Those skilled in the art are clearly understood that above-mentioned
Each chamber size can hold respective liquid amount after set-up mode, such as infusion bag forming, and will not cause infusion bag after filling liquid
Excessive bulging or sunken.
The utility model be used to pack in long chain fat emulsion, amino acid and compound glucose electrolyte injection three
Chamber infusion bag improves the barrier property of infusion bag and oxygen by the way that antioxygen barrier film is arranged in infusion bag outer body.In antioxygen
Oxygen absorbent is placed between barrier film and infusion bag, further increases the antioxidant capacity of infusion bag, extends the pot-life of medicament.It is logical
It crosses using the weak welding rod with the equidirectional radian in side, so that weak welding rod is more easily opened when use, and alternately through
The control of weak welding rod weld strength is opened to avoid opening by mistake, and improves ease of use.By width and height that infusion bag ontology is arranged
The position of medical liquid discharge port is arranged in the ratio of degree, and the liquid residual after reducing infusion improves bag body in especially infusion process
Stability improves medication accuracy and safety.
The utility model selects high security modified polypropylene material known in the art compound as three layers of membrane material preparation
The infusion bag ontology of structure overcomes risk factors and self-defect that the traditional materials such as PVC come, further improves infusion
Heat resistance, clarity and the mechanical strength of bag, improve the safety and stability of infusion products；Simultaneously as trilaminate material
Between there is different fusing points, gradually rise from inside to outside so that heat seal from the inside to the outside when welding, make its more it is tight securely,
Welding effect this product preferably that meets is to the particular/special requirement of weak weldering and fierce different weld strengths.
Detailed description of the invention
Fig. 1 is the three chamber infusion bag structural schematic diagrams of the utility model embodiment 1-5；
Fig. 2 is the three chamber infusion bag structural schematic diagrams of the utility model embodiment 6；
Fig. 3 is the structural schematic diagram of the infusion bag ontology of three chamber infusion bags of the utility model embodiment 7-9.
In figure: 1, infusion bag ontology；2, weak welding rod；3, barrier film；4, oxygen absorbent；5, stress concentrates circular arc；6, liquid feeding mouth.
Specific embodiment
The utility model is made a more thorough explanation below with embodiment.The utility model can be presented as it is a variety of not
Same form, should not be construed as limited to the exemplary embodiments described herein.
The spatially relative terms such as "upper", "lower" " left side " " right side " can be used herein for ease of explanation, for saying
Relationship of the elements or features relative to another elements or features shown in bright figure.It should be understood that in addition in figure
Except the orientation shown, spatial terminology is intended to include the different direction of device in use or operation.For example, if in figure
Device is squeezed, and is stated as being located at other elements or the element of feature "lower" will be located into other elements or feature "upper".Cause
This, exemplary term "lower" may include both upper and lower orientation.Device, which can be positioned in other ways, (to be rotated by 90 ° or is located at
Other orientation), it can be interpreted accordingly used herein of the opposite explanation in space.
Embodiment 1
As shown in Figure 1, three chamber infusion bags in the present embodiment, including infusion bag ontology 1, infusion bag ontology 1 pass through weak weldering
Item 2 is divided into 3 chambers；1 two sides of infusion bag ontology cover Packed barrier film 3.
In order to further decrease the amount that oxygen penetrates into medicament, oxygen absorbent is provided between infusion bag ontology 1 and barrier film 3
4.The form packed with independent oxygen absorbent is arranged in oxygen absorbent, is placed on the region between infusion bag ontology and barrier film.Oxygen uptake
Agent 4 can be bulk, and quantity can be 1 piece, be also possible to muti-piece.
Three chamber infusion bags are distinguished into filling middle long chain fat emulsion, 16 amino acid (16AA) and 36% glucose electrolyte injection
Liquid (625ml, wherein 250ml Amino Acid Compound Injection, 250ml compound glucose injection, 125ml fat emulsion injection),
By adjusting the dosage of oxygen absorbent and the thickness of barrier film or material；By repetition test, discovery is full in oxygen absorbent oxygen uptake ability
Zu≤200ml, barrier bag Yang gas Tou Guo Shuai≤1.0cm3/ (m20.1MPa for 24 hours) when, before the deadline in guarantee drug
The not exceeded lower product cost of impurity is lower.
Wherein, the compound glucose injection of canned 250ml is composed of the following components: glucose H2O 99.0g, phosphorus
Acid dihydride sodium H2O 1.1-1.5g, zinc acetate 2H2O 4.2-4.6mg, appropriate citric acid, remaining is water；
Wherein, canned 250ml Amino Acid Compound Injection is composed of the following components: isoleucine
1.95-2.15g, leucine 2.5-2.9g, lysine hydrochloride 2.35-2.60g, methionine 1.5-1.9g, phenylpropyl alcohol
Propylhomoserin 2.95-3.20g, threonine 1.45-1.75g, tryptophan 0.35-0.70g, valine 2.15-2.45g, arginase 12 .25-
2.55g, histidine monohydrochloride 1.25-1.60g, alanine 4.10-4.45g, L-aminobutanedioic acid 1.15-1.55g, glutamic acid 2.95-
3.20g, glycine 1.25-1.65g, proline 2.75-3.15g, serine 2.45-2.75g, sodium chloride 0.15-0.35g, vinegar
Sour sodium 3H2O 0.12-0.20g, potassium acetate 2.15-2.45g, magnesium acetate 4H2O 0.45-0.65g, calcium chloride 2H2O
0.25-0.55g, sodium hydroxide 0.5-0.9g, appropriate citric acid, remaining is water；
Wherein, the medium and long chain fat emulsion injection of filling 125ml is composed of the following components: soybean oil 10-15 g, middle chain
Triglycerides 10-15g, enuatrol 0.02-0.045g, lecithin 1.3-1.7g, glycerol 3.0-3.3g, Sodium hydroxide q.s.,
Yu Weishui.
Embodiment 2
As shown in Figure 1, three chamber infusion bags in the present embodiment, including infusion bag ontology 1, infusion bag ontology 1 pass through weak weldering
Item 2 is divided into 3 chambers；1 two sides of infusion bag ontology cover Packed barrier film 3.
In order to further decrease the amount that oxygen penetrates into medicament, oxygen absorbent is provided between infusion bag ontology 1 and barrier film 3
4.The form packed with independent oxygen absorbent is arranged in oxygen absorbent, is placed on the region between infusion bag ontology and barrier film.Oxygen uptake
Agent 4 can be bulk, and quantity can be 1 piece, be also possible to muti-piece.
Three chamber infusion bags are distinguished into filling middle long chain fat emulsion, 16 amino acid (16AA) and 16% glucose electrolyte injection
Liquid (wherein 750ml Amino Acid Compound Injection, 750ml compound glucose injection, 375ml fat emulsion injection).
Wherein, the compound glucose injection of canned 750ml is composed of the following components: glucose H2O 132g, phosphorus
Acid dihydride sodium H2O 1.45-1.65g, zinc acetate 2H2O 9.7-10.1mg, appropriate citric acid, remaining is water；
Wherein, canned 750ml Amino Acid Compound Injection is composed of the following components: sodium chloride 1.4-1.7g, acetic acid
Sodium 3H2O 0.75-0.95g, potassium acetate 4.3-4.6g, magnesium acetate 4H2O 0.85-1.1g, calcium chloride 2H2O 0.5-
0.7g, isoleucine 3.3-3.7g, leucine 4.5-4.9g, lysine hydrochloride 4.05-4.4 g, methionine 2.75-3.1g,
Phenylalanine 5.15-5.4g, threonine 2.5-2.9g, tryptophan 0.7-0.95 g, valine 3.7-4.2g, arginine 3.95-
4.25g, histidine monohydrochloride 2.4-2.6g, alanine 7.1-7.45 g, L-aminobutanedioic acid 2.05-2.45g, glutamic acid 5.1-5.4g,
Glycine 2.25-2.65g, proline
4.95-5.3g, serine 4.3-4.7g, sodium hydroxide 1.0-1.4g, appropriate citric acid, remaining is water；
Wherein, the medium and long chain fat emulsion injection of filling 375ml is composed of the following components: soybean oil 35-40 g, middle chain
Triglycerides 35-40g, enuatrol 0.1-0.2g, lecithin 4.2-4.7g, glycerol 9.2-9.5g, Sodium hydroxide q.s., remaining is
Water.
Embodiment 3
As shown in Figure 1, three chamber infusion bags in the present embodiment, including infusion bag ontology 1, infusion bag ontology 1 pass through weak weldering
Item 2 is divided into 3 chambers；1 two sides of infusion bag ontology cover Packed barrier film 3.
In order to further decrease the amount that oxygen penetrates into medicament, oxygen absorbent is provided between infusion bag ontology 1 and barrier film 3
4.The form packed with independent oxygen absorbent is arranged in oxygen absorbent, is placed on the region between infusion bag ontology and barrier film.Oxygen uptake
Agent 4 can be bulk, and quantity can be 1 piece, be also possible to muti-piece.
Three chamber infusion bags are distinguished into filling middle long chain fat emulsion, 16 amino acid (16AA) and 30% glucose electrolyte injection
Liquid (wherein 500ml Amino Acid Compound Injection, 500ml compound glucose injection, 250ml fat emulsion injection).
Wherein, the compound glucose injection of canned 500ml is composed of the following components: glucose H2O 165.0g、
Sodium dihydrogen phosphate H2O 1.95-2.25g, zinc acetate 2H2O 6.45-6.65mg, appropriate citric acid, remaining is water；
Wherein, canned 500ml Amino Acid Compound Injection is composed of the following components: isoleucine
2.6-3.0g, leucine 3.5-3.9g, lysine hydrochloride 3.25-3.6g, methionine 2.15-2.55g, phenylpropyl alcohol ammonia
Sour 4.1-4.35g, threonine 1.95-2.3g, tryptophan 0.5-0.8g, valine 3.0-3.3g, arginine 3.10-3.40g, salt
Sour histidine 1.95-2.15g, alanine 5.6-6.0g, L-aminobutanedioic acid 1.6-2.0g, glutamic acid 4.1-4.4g, glycine 1.7-
2.2g, proline 3 .95-4.2g, serine 3.4-3.8g, calcium chloride 2H2O 0.4-0.7g, magnesium acetate 4H2O 0.65-
0.95g, sodium acetate 3H2O 0.15-0.4g, sodium chloride 0.3-0.6g, potassium acetate 3.2-3.6g, sodium hydroxide 0.7-1.1g,
Appropriate citric acid, remaining is water；
Wherein, the medium and long chain fat emulsion injection of filling 250ml is composed of the following components: soybean oil 20-30 g, middle chain
Triglycerides 20-30g, enuatrol 0.05-0.1g, lecithin 2-4g, glycerol 5.5-7g, Sodium hydroxide q.s., remaining is water.
Embodiment 4
As shown in Figure 1, three chamber infusion bags in the present embodiment, including infusion bag ontology 1, infusion bag ontology 1 pass through weak weldering
Item 2 is divided into 3 chambers；1 two sides of infusion bag ontology cover Packed barrier film 3.
In order to further decrease the amount that oxygen penetrates into medicament, oxygen absorbent is provided between infusion bag ontology 1 and barrier film 3
4.The form packed with independent oxygen absorbent is arranged in oxygen absorbent, is placed on the region between infusion bag ontology and barrier film.Oxygen uptake
Agent 4 can be bulk, and quantity can be 1 piece, be also possible to muti-piece.
By three compartments of three Room liquid liquid infusion bags distinguish filling 250ml ω -3 fish oil medium and long chain fat emulsion injection,
30% glucose injection of 500ml 16 kinds of amino acid injections (16AA) and 500ml.
Wherein, the component of filling 250ml ω -3 fish oil medium and long chain fat emulsion injection are as follows: 15-25g soybean oil, 20-
30g medium chain triglyceride, 3-7g omega-fatty acid triglycerides, 0.05-0.1g enuatrol, 2.5-3.5g lecithin, 5.5-
7.5g glycerol, 0.03-0.05g alpha-tocopherol, Sodium hydroxide q.s., remaining is water.
Wherein, filling 500ml glucose injection is composed of the following components: the Portugal 140-160g in terms of DEXTROSE ANHYDROUS
Grape sugar, 1.95-2.2g sodium dihydrogen phosphate H2O, 0.002-0.008g zinc acetate 2H2O, remaining is water.
Wherein, filling 500ml amino acid injection is made of following components and remaining water: isoleucine 2.5-
3.0g, leucine 3.5-3.9g, lysine hydrochloride 3.2-3.75g, methionine 2.15-2.55g, phenylalanine 4.0-4.4g,
Threonine 1.95-2.30g, tryptophan 0.5-0.8g, valine 2.8-3.3g, arginine 3.1-3.4g, histidine monohydrochloride 1.9-
2.2g, alanine 5.5-6.0g, L-aminobutanedioic acid 1.5-2.0g, glutamic acid
4.0-4.4g, glycine 1.7-2.2g, proline 3 .8-4.2g, serine 3.4-3.8g, sodium chloride
0.3-0.7g, sodium acetate 3H2O 0.1-0.4g, potassium acetate 3.2-3.6g, magnesium acetate 4H2O 0.6-1.0g, chlorine
Change calcium 2H2O 0.3-0.7g, sodium hydroxide 0.7-1.1g, remaining is water.
Embodiment 5
As shown in Figure 1, three chamber infusion bags in the present embodiment, including infusion bag ontology 1, infusion bag ontology 1 pass through weak weldering
Item 2 is divided into 3 chambers；1 two sides of infusion bag ontology cover Packed barrier film 3.
In order to further decrease the amount that oxygen penetrates into medicament, oxygen absorbent is provided between infusion bag ontology 1 and barrier film 3
4.The form packed with independent oxygen absorbent is arranged in oxygen absorbent, is placed on the region between infusion bag ontology and barrier film.Oxygen uptake
Agent 4 can be bulk, and quantity can be 1 piece, be also possible to muti-piece.
By three compartments of three Room liquid liquid infusion bags distinguish filling 125ml ω -3 fish oil medium and long chain fat emulsion injection,
36% glucose injection of 16 kinds of amino acid injections (16AA) and 250ml of 250ml.
Wherein, the component of filling 125ml ω -3 fish oil medium and long chain fat emulsion injection are as follows: 7.5-12.5 soybean oil, 10-
15g medium chain triglyceride, 2-3g omega-fatty acid triglycerides, 0.02-0.04g enuatrol, 1-2g lecithin, 2.5-4.5g
Glycerol, 0.01-0.04g alpha-tocopherol, Sodium hydroxide q.s., remaining is water.
Wherein, 36% glucose injection of filling 250ml is composed of the following components: glucose H2O 99.0 g、
Sodium dihydrogen phosphate H2O 1.1-1.5g, zinc acetate 2H2O 4.2-4.6mg, appropriate citric acid, remaining is water.
Wherein, 16 kinds of amino acid injections (16AA) of filling 250ml are made of following components and remaining water: different bright
Propylhomoserin 1.95-2.15g, leucine 2.5-2.9g, lysine hydrochloride 2.35-2.60g, methionine 1.5-1.9g, phenylalanine
2.95-3.20g, threonine 1.45-1.75g, tryptophan 0.35-0.70g, valine 2.15-2.45g, arginase 12 .25-
2.55g, histidine monohydrochloride 1.25-1.60g, alanine 4.10-4.45g, L-aminobutanedioic acid 1.15-1.55g, glutamic acid 2.95-
3.20g, glycine 1.25-1.65g, proline 2.75-3.15g, serine 2.45-2.75g, sodium chloride 0.15-0.35g, vinegar
Sour sodium 3H2O 0.12-0.20g, potassium acetate 2.15-2.45g, magnesium acetate 4H2O 0.45-0.65g, calcium chloride 2H2O
0.25-0.55g, sodium hydroxide 0.5-0.9g, appropriate citric acid, remaining is water；
Embodiment 6
As shown in Fig. 2, three chamber infusion bags of the present embodiment, still include the infusion bag ontology for being divided into 3 chambers, with reality
It applies unlike a 1-5, in order to keep oxygen uptake ability in barrier film uniform, oxygen absorbent 4 is fixed on barrier film 3 with coating form
On, coating can be plane coating, stripe coating or netted coating.
Embodiment 7
As shown in figure 3, the infusion bag ontology 1 of the present embodiment, infusion bag ontology 1 are mainly made of modified polypropene, pass through
Weak welding rod 2 is divided into 3 chambers, and the weld strength of weak welding rod 2 is 10N/15mm, and in the same side, setting stress concentrates circular arc 5, answers
The diameter of power circular arc 5 is 12mm, and stress concentrates circular arc 5 to be located at weak welding rod close to the side of liquid feeding mouth 6；Certainly, in other implementations
In example, also it can be set in side of the weak welding rod far from liquid feeding mouth 6.
When using three chamber infusion bag of the present embodiment, infusion bag ontology 1 is taken out from the barrier film 3 of sealing, it will be defeated
Liquid bag ontology is squeezed since the side opposite with liquid feeding mouth to liquid feeding mouth direction in any way, such as to crimp infusion bag
Mode is squeezed to liquid feeding mouth direction, and the stress that stress point concentrates on weak welding rod concentrates 5 region of circular arc, can help the hand of weak welding rod
It is dynamic to open.And three chamber infusion bags of the present embodiment are in storage and transport, and are not susceptible to open by mistake and open.
A series of infusion bag ontologies including the infusion bag ontology of the present embodiment are placed on storage transport test dress
It is tested in setting, the structure of these infusion bag ontologies is similar to Example 7, unlike, the stress of these infusion bag ontologies
The diameter of circular arc 5 is is respectively 0mm (unstressed circular arc), 2mm, 3mm, 5mm, 8mm, 12mm, 20mm, 25mm, through repetition test
It was found that the infusion bag ontology that stress arc diameter is 25mm is significantly larger than this examination in the rate of opening that opens by mistake stored in trafficking experiments device
The infusion bag ontology of other stress arc diameters opens by mistake the rate of opening in testing.Further, after storing trafficking experiments, by institute
Some infusion bag ontologies take out, manually opened, find through repetition test, and stress arc diameter is the infusion bag of 0mm, 2mm, 3mm
Ontology, manually opened difficulty is big, is far longer than the manually opened difficulty of the infusion bag ontology of other stress arc diameters in this test
Degree, especially the infusion bag ontology of stress arc diameter 0mm, manually opened difficulty are maximum.
Embodiment 8
As shown in figure 3, the infusion bag ontology 1 of the present embodiment, the width of infusion bag ontology 1 and the ratio of height are 0.8, each
Chamber is provided with a liquid feeding mouth 6, and liquid feeding mouth 6 can also be used as medical fluid delivery outlet, in the present embodiment, in order to further subtract
The liquid residue of few infusion port, selects a liquid feeding mouth in two side cavities as medical fluid delivery outlet, as medical fluid delivery outlet
The position of liquid feeding mouth the real welding rod side in the short transverse of this chamber is positioned close in a manner of being integrally formed, in this implementation
In example, the liquid feeding mouth of two side cavities is arranged in this wise, and the option as medical fluid delivery outlet is selective.In fact, should manage
The liquid feeding mouth of leftmost side chamber or rightmost side chamber also can be set in a manner of being for example integrally formed as close to most left in solution
Real welding rod in the short transverse of side or the rightmost side, the liquid feeding mouth being arranged so are preferentially selected as medical fluid output when in use
Mouthful, there is no restriction for the setting position of the liquid feeding mouth of other chambers.
Three chamber infusion bags are distinguished into filling middle long chain fat emulsion, 16 amino acid (16AA) and 36% glucose electrolyte injection
Liquid (1250ml ml, wherein inject by 500ml Amino Acid Compound Injection, 500ml compound glucose injection, 250ml Fat Emulsion
Liquid), the ratio of the width and height that adjust different infusion bag ontologies obtains different pouch-shapeds；By repetition test, find in width
When the ratio of degree and height is 1.2, the Liquid Residue scale of construction will be more than 1%, extreme influence infusion accuracy.
Different in width and the infusion bag ontology of height ratio (the ratio of width to height) are further subjected to filling test (1250ml
Ml, wherein 500ml Amino Acid Compound Injection, 500ml compound glucose injection, 250ml fat emulsion injection), remove width
Other than different with height ratio, the other structures feature of infusion bag is identical as the present embodiment, and width and height ratio are respectively
0.5,0.7,0.8,0.9,1.0,1.3,1.5, found by repetition test, width and height ratio be 0.5 and 1.3,1.5 it is defeated
The infusion bag ontology that the liquid residue of liquid bag ontology is significantly greater than width and height ratio is 0.7,0.8,0.9,1.0, and
At the end of infusion closes on, the infusion bag ontology that width and height ratio are 0.5 and 1.3,1.5 is than other the ratio of width to height in this test
Infusion bag be easier to run-off the straight.
Embodiment 9
16 kinds of ammonia of 16% compound glucose injection, 500ml of filling 500ml are distinguished in infusion bag shown in Fig. 3
Base acid injection (16AA) and 250ml medium and long chain fat emulsion injection are investigated after 121 DEG C of moist heat sterilizations by example of the product
The packaging material performance of infusion bag,
Thermal adaptability: taking each 5 bags of above-mentioned sample, removes outer bag, places 24 hours under the conditions of -25 DEG C ± 2 DEG C, then
Continue to place 24 hours under the conditions of 50 DEG C ± 2 DEG C, then placed 24 hours under the conditions of 23 DEG C ± 2 DEG C, first into each sample
Between appropriate 1% methylene blue solution is added in chamber.Then sample is folded along weak weldering and is placed 5 minutes, colored solutions must not be from
Intermediate cavity is seeped into both sides chamber；It is again that the weak weldering of each chamber is fully open, then sample is placed between two parallel-plates, is born
The internal pressure of 67kPa maintains 10 minutes, and bag body surrounding (real weldering position) must not have liquid leakage.
Light transmittance: taking each 5 bags of this product, discard chamber contents, choose smooth position, be cut into the slice of 5 0.9*4cm,
Cleaned up, be put into absorption cell along light incident direction respectively, topped up with water with deionized water, and using water as blank, according to it is ultraviolet-
Visible spectrophotometry (four general rules 0401 of " Chinese Pharmacopoeia " version in 2015) measures light transmittance at 450nm.
Inner bag heat sealing strength: taking 1 bag of each batch of sample, according to compound in heat sealing strength measuring method (YBB00122003-2015)
The method measurement of bag.
Overall tightness: each 10 bags of this product, respectively by sample be put into dress water closed container in, keep bag body in water by
It floods completely, to the negative pressure of container application -67kPa, keeps 5min, must not there is bubble to overflow from bag body into water.
Test result is as follows:
By test result it is found that three layers of infusion bag being made into of modified polypropylene material are selected in the utility model, at 121 DEG C
Still have good light transmittance in each test phase after moist heat sterilization, 88% or more, meet relevant criterion, shows this
Utility model membrane material heat resistance is good；The membrane material weak weldering position in temperature adaptability test is able to bear the pressure of 30kPa
Power and be not turned on, real weldering is able to bear the pressure of 67kPa and no liquid leaks out, and weldering part heat sealing strength is not in fact for inner bag bag body surrounding
Lower than 20N/15mm, weak weldering position is not less than 5N/15mm, and is not higher than 12N/15mm, and infusion bag overall tightness is good, it is seen that
The heat seal welding carried out using the utility model trilamellar membrane material can be good at the tool for adapting to the weak weldering of this three chamber infusion bag and welding in fact
Body needs, product mechanical strength with higher.
After three chamber injections are mixed, the compatibility and safety of infusion bag material and injection are further investigated, as a result
It is as shown in the table:
The results show that the infusion bag of the utility model modified polypropene material preparation, not plasticizer-containing, with middle long-chain fat
Cream, 16 kinds of amino acid (16AA) and 16% glucose electrolyte injection compatibility it is good, conventional character is good, osmol
Your concentration, milk particle, Bacteria Detection, endotoxin detection, undue toxicity detection and conventional shape etc. meet pharmacopoeial requirements, and display is originally
The middle long chain fat emulsion of utility model, amino acid and the three chamber infusion products safety of compound glucose electrolyte injection are good
It is good.
In conclusion three chamber infusion bags of the application have the following characteristics that
(1) the setting extension of oxygen absorbent and barrier bag includes the pharmaceutical liquid pot-life；
(2) welding rod is not easy to open by mistake during transporting or save, and it is convenient to open when use；
(3) discharge of the Width x Height than being conducive to include pharmaceutical liquid of the setting position of outlet, pouch-shaped；
(4) selection of modified polypropene membrane material further improves drug safety, clarity and mechanical performance.
Above-mentioned example is only intended to illustrate the utility model, and in addition to this, also there are many different embodiments, and these
Embodiment be all those skilled in the art after comprehension the utility model thought it is also envisioned that therefore, no longer arrange one by one herein
It lifts.
Claims (9)
1. a kind of three Room infusion for long chain fat emulsion, amino acid and compound glucose electrolyte injection in packing
Bag, including infusion bag ontology, the infusion bag ontology are divided into first chamber, second chamber and third chamber by weak welding rod；
Infusion bag ontology two sides cover Packed barrier film, and oxygen absorbent, institute are provided between infusion bag ontology and the barrier film
The ratio of the width and height of stating infusion bag ontology is 0.7 to 1.0, and one end of the weak welding rod is provided with stress and concentrates circular arc, institute
Stating stress and concentrating the arc radius of circular arc is 5mm between 23mm；Wherein:
(1) first chamber, second chamber and third chamber are packaged with 36% compound glucose electrolyte injection, 16 respectively
Amino acid (16AA) injection and medium and long chain fat emulsion injection, liquid amount are respectively 250ml, 250ml and 125ml；
Or liquid amount is respectively 500ml, 500ml and 250ml；
(2) first chamber, second chamber and third chamber are packaged with 16% compound glucose electrolyte injection, 16 respectively
Amino acid (16AA) injection and medium and long chain fat emulsion injection, liquid amount are respectively 500ml, 500ml and 250ml,
Or liquid amount is respectively 750ml, 750ml and 375ml；
(3) first chamber, second chamber and third chamber are packaged with 30% compound glucose electrolyte injection, 16 respectively
Amino acid (16AA) injection and medium and long chain fat emulsion injection, liquid amount are respectively 500ml, 500ml and 250ml,
Or liquid amount is respectively 750ml, 750ml and 375ml；
(4) first chamber, second chamber and third chamber are packaged with ω -3 fish oil medium and long chain fat emulsion injection, 16 respectively
Amino acid (16AA) injection and 30% compound glucose electrolyte injection, liquid amount is respectively 250ml, 500ml
And 500ml perhaps liquid amount be respectively 375ml, 750ml and 750ml or liquid amount be respectively 500ml, 1000ml and
1000ml；Or
(5) first chamber, second chamber and third chamber are packaged with ω -3 fish oil medium and long chain fat emulsion injection, 16 respectively
Amino acid (16AA) injection and 36% compound glucose electrolyte injection, liquid amount is respectively 125ml, 250ml
And 250ml perhaps liquid amount be respectively 250ml, 500ml and 500ml or liquid amount be respectively 375ml, 750ml and
750ml or liquid amount are respectively 500ml, 1000ml and 1000ml.
2. three chamber infusion bag according to claim 1, wherein any in the liquid feeding mouth of the two sides of the bottom of infusion bag ontology
A or multiple middle positions that this chamber is arranged far from a manner of integrally formed.
3. three chamber infusion bag according to claim 2, wherein the liquid feeding mouth is as medical liquid discharge port, as far as possible with infusion
Ipsilateral real welding rod in the short transverse of bag ontology is close.
4. three chamber infusion bag according to claim 1 or 2, which is characterized in that the oxygen absorbent is bulk, and quantity is 1 piece
Or muti-piece.
5. three chamber infusion bag according to claim 1 or 2, which is characterized in that the oxygen absorbent is plane coating, strip painting
Layer or netted coating；Or the oxygen absorbent is one or more independent oxygen absorbent packagings.
6. three chamber infusion bag according to claim 1 or 2, which is characterized in that the oxygen uptake ability of the oxygen absorbent is not less than
200ml；Or the oxygen transit dose of the barrier film is not more than 1.0cm3/(m2Its 0.1MPa).
7. three chamber infusion bag according to claim 1 or 2, which is characterized in that the stress concentrates circular arc to be positioned close to
One end of liquid feeding mouth.
8. three chamber infusion bag according to claim 1 or 2, which is characterized in that the stress concentrates the arc radius of circular arc
For 8mm-20mm.
9. three chamber infusion bag according to claim 1 or 2, which is characterized in that the weld strength of the weak welding rod is 5N/
15mm-12N/15mm。
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| Application Number | Priority Date | Filing Date | Title |
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| CN2016207406580 | 2016-07-14 | ||
| CN2016207406612 | 2016-07-14 | ||
| CN2016207422278 | 2016-07-14 | ||
| CN201620740902 | 2016-07-14 | ||
| CN2016207419063 | 2016-07-14 | ||
| CN201620740661 | 2016-07-14 | ||
| CN201620742227 | 2016-07-14 | ||
| CN201620741906 | 2016-07-14 | ||
| CN2016207409023 | 2016-07-14 | ||
| CN201620740658 | 2016-07-14 |
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| CN201720833177.9U Active CN208877295U (en) | 2016-07-14 | 2017-07-11 | A kind of three chamber infusion bags for long chain fat emulsion, amino acid and compound glucose electrolyte injection in packing |
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