For detecting and calibrating the tool of ophthalmology imaging, ophthalmology biological parameter measuring instrument
Technical field
This patent be related to it is a kind of for detecting and calibrate the tool of fundus imaging instrument field range, more particularly to detection and
Calibrate the tool of Optical coherence tomography (OCT) system field range.It can also be used for distortion, the inspection of calibration ophthalmoscopic image
It surveys and calibrates ophthalmology bio-measurement instrument and tie the axis oculi of the corneal curvature of coherence tomography, ophthalmology bio-measurement instrument at the moment
Length etc..
Background technique
The continuous improvement of ophthalmoscopic image technology is largely benefited from the development of ophthalmology medicine, including traditional crack
Lamp (slit lamp), colored fundus camera (color fundus camera), confocal scanning laser ophthalmoscope (confocal
Scanning laser ophthalmoscope) etc..
Optical coherence tomography (OCT) is a kind of 3 dimension imaging technology, it has a wide range of applications field, especially
It is biomedical imaging.OCT technology has many advantages, such as that high-resolution, image taking speed be fast and high sensitivity.Since 1996 first
Since Tianwan businessman is come out with OCT image equipment, OCT technology has greatly pushed the development of Ophthalmologic Diagnostics.In the latest 20 years, with
Technology constantly updates, and image taking speed, sensitivity, resolution ratio and the imaging depth of OCT technology are also being constantly progressive.
It is all these to be used to check that the image instrument on eyeground has an important technical indicator, that is, the visual field of imaging
Range (field ofview).The field-of-view angle of funduscopy typically refers to visual angle (angle observed by corresponding human eye
Ofview), as shown in Figure 1,1 is eyes, 2 be the visual angle being observed that.
Similar with the visual angle of ordinary camera, which can also be subdivided into horizontal, vertical and cornerwise different views again
Angle, as shown in Figure 2.
Recently as the development of ophthalmoscopic image technology, corresponding instrument field-of-view angle is being continuously increased, more than 40 °
Field-of-view angle is increasingly universal.
For ophthalmoscopic image instrument manufacturer, the detection and calibration of big field-of-view angle are not very easy.Such as it is existing
Have in technology, international standard ISO-16971 recommends a kind of optical performance test tool of OCT instrument, and as shown in Figure 3: 1 is work
Has outer lens barrel (length is approximately equal to 17mm), 2 be lens (focal length is approximately equal to 17mm), and 3 be diaphragm (diameter is approximately equal to 6mm), and 4 are
Individual filament (diameter is approximately equal to 100 μm), 5 be neutral-density filter, and 6 be sheet glass (with a thickness of 1mm), and 7 be to indicate size
Scale plate.The size scale for paying attention to scale plate 7 in figure is exactly the detection and calibration for the OCT instrument visual field.But the test
Tool is suitable only for smaller field-of-view angle (near optical shaft orientation).If the width of simple extension scale plate 7, from optical axis
Farther away fringe region is extremely difficult to clearly image quality.In addition, shown in the corresponding image height of the scale of scale plate 7 and Fig. 1
Angle of visibility be not stringent proportional relation, if without non-liner revision error can be brought to the measurement of angle of visibility.
Utility model content
Purpose of utility model: big angle of visibility can not be detected and calibrated in order to solve optical performance test tool in the prior art
The problem of spending, the utility model provide a kind of for detecting and calibrating the tool of ophthalmology imaging.Meanwhile the utility model also can be used
In detecting and calibrating ophthalmology bio-measurement instrument and tie the corneal curvature of coherence tomography at the moment, ophthalmology biology is detected and calibrated
The axiallength of measuring instrument.
Technical solution: a kind of for detecting and calibrating the tool of ophthalmology imaging, ophthalmology biological parameter measuring instrument, feature
It is, including optics forepiece and optics back part;Optics forepiece includes the first cylindrical body and the first ball-crown body, the first spherical crown
The bottom surface of body is identical as the bottom surface size of the first cylindrical body;Optics back part include the second cylindrical body and the second ball-crown body, second
The bottom surface of ball-crown body is identical as the bottom surface size of the second cylindrical body;First cylindrical body, the second cylindrical body include the first bottom surface and
First bottom surface of the second bottom surface, the first cylindrical body is overlapped with the bottom surface of the first ball-crown body;Second bottom surface of the first cylindrical body and the
First bottom surface of two cylindrical bodies connects, and the circle in the center of circle of the second bottom surface of the first cylindrical body and the first bottom surface of the second cylindrical body
The heart coincides;Second bottom surface of the second cylindrical body is overlapped with the bottom surface of the second ball-crown body;The spherical crown surface of first ball-crown body is polishing
Face, the spherical crown surface of the second ball-crown body are buffed surface.
Preferably, the first ball-crown body includes the first spherical crown curved surface, the first spherical crown curved surface center of circle and first the second bottom of cylindrical body
The face center of circle is overlapped;Second ball-crown body includes the second spherical crown curved surface, the second spherical crown curved surface center of circle and second the first bottom surface of cylindrical body circle
The heart is overlapped.
Preferably, basal diameter of the basal diameter of the first cylindrical body less than the second cylindrical body.
Preferably, the first spherical crown curved surface and the second spherical crown curved surface are convex surface, wherein the first spherical crown curved surface is convex ball
Face, radius 5.6mm~9mm.
Preferably, between the first cylindrical body and the first ball-crown body, between the first cylindrical body and the second cylindrical body, the second cylinder
Coaxial gluing is formed or is integrally formed between body and the second ball-crown body.
Preferably, first ball-crown body, the first cylindrical body, the second cylindrical body and the second spherical crown body by integral forming.
Preferably, the effective focal length range of the tool is 10.5mm-18mm, the effective focal length for the human eye that is near the mark
16.7mm。
Preferably, the spherical crown surface of the second ball-crown body is equipped with multiple concentric circles.
Preferably, multiple radiation and one or more witness markers are additionally provided on the spherical crown surface of the second ball-crown body.
Preferably, for detecting and calibrating the field range of fundus imaging instrument.
The utility model has the advantages that the prior art that compares, the utility model provides a kind of for detecting and calibrating ophthalmology imaging, eye
The tool of section's biological parameter measuring instrument, has the advantage that
1, it can be used for adjusting the field of view center registration of different light paths;
2, it can be used for detecting fundus imaging instrument field range;It is able to detect and calibrates 50 ° of even greater angle of visibilities
Degree;And it is more accurate to wide-field measurement;
3, it can be used for detecting the distortion with calibration ophthalmoscopic image;
4, it can be used for detecting and calibrating ophthalmology bio-measurement instrument and tie the corneal curvature of coherence tomography at the moment;
5, it can be used for detecting and calibrating the axiallength of ophthalmology bio-measurement instrument;
6, the tool is easy to process, is segmented into several part processing, is also suitable for one-pass molding.
Detailed description of the invention
Fig. 1 is funduscopy field-of-view angle schematic diagram;
Fig. 2 is in horizontal, vertical, diagonal line different directions field-of-view angle;
Fig. 3 is the tool for being used to test OCT instrumental optics performance that international standard ISO-16971 recommends;
Fig. 4 is the structure for the tool that the utility model embodiment one is used to detect and calibrate fundus imaging instrument field range
Schematic diagram;
Fig. 5 is the structural schematic diagram and concentric circles of the utility model embodiment one;
Fig. 6 is the structural schematic diagram of embodiment two;
Fig. 7 is the structural schematic diagram of embodiment three;
Fig. 8 is the structural schematic diagram of example IV.
Specific embodiment
The utility model is described in further detail in the following with reference to the drawings and specific embodiments.
Embodiment one:
As shown in figure 4, a kind of for detecting and calibrating the tool of ophthalmology imaging and bio-measurement instrument, including optics front
Part 01 and optics back part 02, optics forepiece 01 are all made of N-BK7 type glass with optics back part 02 and are made;Optics front
Part 01 includes the first cylindrical body 011 and the first ball-crown body 012, the bottom surface of the bottom surface of the first ball-crown body 012 and the first cylindrical body 011
Size is identical;Optics back part 02 includes the second cylindrical body 021 and the second ball-crown body 022, the bottom surface of the second ball-crown body 022 and the
The bottom surface size of two cylindrical bodies 021 is identical;First cylindrical body 011, the second cylindrical body 021 include the first bottom surface and the second bottom
Face, the first bottom surface of the first cylindrical body 011 are overlapped with the bottom surface of the first ball-crown body 012;First cylindrical body 011 and the second cylindrical body
Coaxial closely sealed between 021, i.e., the second bottom surface of the first cylindrical body 011 is connect with the first bottom surface of the second cylindrical body 021, and first
The center of circle of second bottom surface of cylindrical body 011 and the center of circle of the first bottom surface of the second cylindrical body 021 coincide;Second cylindrical body 021
The second bottom surface be overlapped with the bottom surface of the second ball-crown body 022;First cylindrical body 011, the first ball-crown body 012, the second cylindrical body
021 and second ball-crown body 022 be integrally formed, gluing coaxial between different piece can also be made.
As shown in figure 4, the spherical crown surface of first ball-crown body 012 is burnishing surface in optics forepiece 01, in optics back part 02
The spherical crown surface of second ball-crown body 022 is buffed surface.
The spherical crown surface of the tool optic forepiece 01 generates convergence effect to the incident parallel light of different angle, and after optics
The spherical crown surface of component 02 is corresponding focusing surface.The length and spherical radius of former and later two components are optimized by optical design.The
One ball-crown body 012 includes the first spherical crown curved surface, and the first spherical crown curved surface centre of sphere is overlapped with the 011 second bottom surface center of circle of the first cylindrical body;
Second ball-crown body 022 includes the second spherical crown curved surface, the second spherical crown curved surface centre of sphere and the 021 first bottom surface center of circle of the second cylindrical body weight
It closes;The center of circle overlapping position is the conjugation pupil place that the tool is the optical path that ophthalmological instrument is calibrated;The incidence of different angle
Directional light all passes through a pivoting point (pivot point), that is, the faying face of above-mentioned first cylindrical body and the second cylindrical body
Geometric center, the incident parallel light of different angle is represented in figure by the straight line of pivoting point.Tool mould to a certain extent
Anthropomorphic eye: the cornea of the corresponding human eye of the spherical surface (polishing) of optics forepiece 01, and the spherical surface (polishing) of optics back part 02 is corresponding
The retina of human eye.Pivoting point between the component of front and back corresponds to the position of pupil of human.The work is a difference in that with human eye
Has no corresponding crystalline lens, therefore all dioptric effects both are from the spherical surface of forepiece.
This embodiment is designed for 805nm wavelength.When object distance setting can be on back part convex surface at -758mm
Blur-free imaging.
Therefore first spherical crown subsequent corrosion 8.85mm collects directional light close to eye cornea radius statistical result 7.8mm. and enters
It is mapped to the reflection light in the face, can be used as keratometry calibration and usage.Second spherical crown subsequent corrosion is 16.67mm.First
Cylindrical body basal diameter is 13mm, the second cylindrical body basal diameter be the first ball-crown body of 22mm. and the first cylindrical body thickness and
For 8.85mm, the thickness of the second ball-crown body and the second cylindrical body and be 16.67mm, the overall thickness of entire tool is 25.52mm, with
Relatively, total optical path is equivalent to the human eye that length is 29mm to standard human eye, is greater than standard human eye 24mm, but still in common eye
Within the measurement range (14mm to 32mm) of section's bio-measurement instrument, axiallength measurement calibration and usage can be used as.
The range maximum of the measurement of the present embodiment field range and distortion calibration is up to 80 degree.
Structural schematic diagram in this embodiment after optical design optimizes is as shown in Figure 5.
As human eye, which is a simple imaging system.For more preferable simulation human eye, the tool it is effective
Focal length (effective focal length) is also configured as standard human eye, and the effective focal length in this embodiment is about
For 17mm (diopter is about 60diopters), the focal length for the human eye that is near the mark.
In order to simulate diffusing scattering (diffuse scattering) effect of human eye retina, the spherical crown surface of the second ball-crown body
Do grinding process.
In order to measure the angle of incident ray, as shown in figure 5, the spherical crown surface of the second ball-crown body 022 is equipped with several together
Heart circle 03, the corresponding certain incidence angle of each concentric circles 03.There are 12 concentric circles, two neighboring concentric circles in the present embodiment
Corresponding 2.5 ° of the field-of-view angle (corresponding arc length is approximately equal to 0.73mm on the second spherical crown surface) of 03 radius spacing, so 12 same
The corresponding total visual field angle of heart circle is 2.5 ° × 2 × 12=60 °, and (corresponding arc length is approximately equal on the second spherical crown surface
17.5mm), the range that the tool much larger than Fig. 3 can measure.In addition to concentric circles 03, also it is printed on the spherical crown surface of optics back part
A series of radiation and several positioning stains, these increased lines and point can be used for detecting the eyeground of fundus imaging instrument intake
Whether image has rotation or overturning, so especially suitable for detection and calibration fundus imaging instrument tool.In this embodiment,
From the first spherical crown towards in tool, positioning stain is located at horizontal radial line lower right.If in the intake of fundus imaging instrument
Stain is positioned in eye fundus image and is located at other orientation, then illustrates that image has rotation or overturning.The tool is in addition to can detecte eye
Outside section's imaging, ophthalmology biological parameter measuring instrument, it can also be calibrated, i.e., according to the result of actual measurement in instrument
It adjusts on software or hardware to the field range of imaging, so that final field angle is consistent with the nominal value of instrument.
Embodiment two:
As shown in fig. 6, a kind of for detecting and calibrating the tool of ophthalmology imaging and bio-measurement instrument, including optics front
Part 03 and optics back part 04, optics forepiece 03 are all made of N-BK7 type glass with optics back part 04 and are made;Optics front
Part 03 includes the first cylindrical body 031 and the first ball-crown body 032, the bottom surface of the bottom surface of the first ball-crown body 032 and the first cylindrical body 031
Size is identical;Optics back part 04 includes the second cylindrical body 041 and the second ball-crown body 042, the bottom surface of the second ball-crown body 042 and the
The bottom surface size of two cylindrical bodies 041 is identical;First cylindrical body 031, the second cylindrical body 041 include the first bottom surface and the second bottom
Face, the first bottom surface of the first cylindrical body 031 are overlapped with the bottom surface of the first ball-crown body 032;First cylindrical body 031 and the second cylindrical body
Coaxial closely sealed between 041, i.e., the second bottom surface of the first cylindrical body 031 is connect with the first bottom surface of the second cylindrical body 041, and first
The center of circle of second bottom surface of cylindrical body 031 and the center of circle of the first bottom surface of the second cylindrical body 041 coincide;Second cylindrical body 041
The second bottom surface be overlapped with the bottom surface of the second ball-crown body 042;First cylindrical body 031, the first ball-crown body 032, the second cylindrical body
041 and second ball-crown body 042 be integrally formed, gluing coaxial between different piece can also be made.
As shown in fig. 6, the spherical crown surface of first ball-crown body 032 is burnishing surface in optics forepiece 03, in optics back part 04
The spherical crown surface of second ball-crown body 042 is buffed surface.
The spherical crown surface of the tool optic forepiece 03 generates convergence effect to the incident parallel light of different angle, and after optics
The spherical crown surface of component 04 is corresponding focusing surface.The length and spherical radius of former and later two components are optimized by optical design.The
One spherical crown surface, the 032 convex surface center of circle is overlapped with the 031 second bottom surface center of circle of the first cylindrical body;Second spherical crown, the 042 convex surface center of circle and second
The 041 first bottom surface center of circle of cylindrical body is overlapped;The center of circle overlapping position is the conjugation that the tool is the optical path that ophthalmological instrument is calibrated
Where pupil;The incident parallel light of different angle all passes through a pivoting point (pivot point), that is, above-mentioned first cylinder
The geometric center of the faying face of body and the second cylindrical body represents the incident parallel of different angle in figure by the straight line of pivoting point
Light.The tool simulates human eye to a certain extent: the cornea of the corresponding human eye of the spherical surface (polishing) of optics forepiece 03, and after optics
The retina of the corresponding human eye of the spherical surface (polishing) of component 04.Pivoting point between the component of front and back corresponds to the position of pupil of human
It sets.It is a difference in that the tool does not have corresponding crystalline lens with human eye, therefore all dioptric effects both are from the ball of forepiece
Face.
The present embodiment is designed for zero diopter of 805nm wavelength, and the effective focal length of the tool is about 15.2mm.Work as object distance
Design at infinity, can be equivalent to and retina is imaged in zero diopter in back part convex surface blur-free imaging.
First spherical crown curved surface, 032 radius 7.8mm is consistent with eye cornea radius statistical result.Therefore it is incident to collect directional light
To the reflection light in the face, keratometry calibration and usage can be used as.Second spherical crown, 042 subsequent corrosion is 15.2mm.Total thickness
Degree is 23.0mm, and relatively with standard human eye, total optical path is equivalent to the human eye that length is 26mm, is slightly larger than standard human eye
24mm, but still can be used as axiallength measurement calibration and usage in the measurement range of common ophthalmological bio-measurement instrument.
The range maximum of the measurement of the present embodiment field range and distortion calibration is up to 120 degree.
Embodiment three:
The structure of the present embodiment is identical as embodiment one and two, is designed for zero diopter of 805nm wavelength, has in size
Institute is different, if 052 subsequent corrosion of the first spherical crown in Fig. 7 the present embodiment is 5.6mm, is equivalent to clinically the smallest children's cornea
Radius.Second spherical crown, 062 subsequent corrosion is 10.9mm, which is about 10.9mm, and overall thickness 16.5mm is equivalent to
Length this embodiment of 19mm human eye length is suitable for the inspection and calibration of children's ophthalmic product.
The range maximum of the measurement of the present embodiment field range and distortion calibration is up to 120 degree.
Example IV:
The structure of the present embodiment is identical as embodiment one and two, is designed for zero diopter of 805nm wavelength, has in size
Institute is different, if 072 subsequent corrosion of the first spherical crown in Fig. 8 the present embodiment is 9.0mm, is equivalent to clinically maximum adult angle
Film radius.Second spherical surface, 082 radius is 17.6mm, which is about 17.6mm, and overall thickness 26.6mm is equivalent to length
30mm human eye length is spent, still in the measurement range of common ophthalmological bio-measurement instrument, close to the measurement upper limit.
The range maximum of the measurement of the present embodiment field range and distortion calibration is up to 120 degree.