CN208780672U - A kind of gel release oxygen detection device - Google Patents
A kind of gel release oxygen detection device Download PDFInfo
- Publication number
- CN208780672U CN208780672U CN201820976889.0U CN201820976889U CN208780672U CN 208780672 U CN208780672 U CN 208780672U CN 201820976889 U CN201820976889 U CN 201820976889U CN 208780672 U CN208780672 U CN 208780672U
- Authority
- CN
- China
- Prior art keywords
- oxygen
- open
- entrance
- top receptacle
- gel
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 title claims abstract description 157
- 239000001301 oxygen Substances 0.000 title claims abstract description 157
- 229910052760 oxygen Inorganic materials 0.000 title claims abstract description 157
- 238000001514 detection method Methods 0.000 title claims abstract description 20
- 238000005259 measurement Methods 0.000 claims abstract description 38
- 238000004891 communication Methods 0.000 claims abstract description 3
- 239000000523 sample Substances 0.000 claims description 8
- -1 polyethylene Polymers 0.000 claims description 6
- 239000004698 Polyethylene Substances 0.000 claims description 4
- 229920000573 polyethylene Polymers 0.000 claims description 4
- 229920000915 polyvinyl chloride Polymers 0.000 claims description 4
- 239000004800 polyvinyl chloride Substances 0.000 claims description 4
- MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical group O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 claims description 2
- 229910001882 dioxygen Inorganic materials 0.000 claims description 2
- 239000000499 gel Substances 0.000 abstract description 41
- 238000012360 testing method Methods 0.000 abstract description 22
- 239000007853 buffer solution Substances 0.000 abstract description 16
- 239000007789 gas Substances 0.000 abstract description 8
- 230000008859 change Effects 0.000 abstract description 4
- 238000007405 data analysis Methods 0.000 abstract description 4
- 230000008901 benefit Effects 0.000 abstract description 3
- 239000000463 material Substances 0.000 description 9
- 206010052428 Wound Diseases 0.000 description 7
- 208000027418 Wounds and injury Diseases 0.000 description 7
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 6
- 238000010998 test method Methods 0.000 description 6
- 229920001971 elastomer Polymers 0.000 description 5
- 230000006872 improvement Effects 0.000 description 5
- 238000000034 method Methods 0.000 description 5
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 4
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 4
- 238000010586 diagram Methods 0.000 description 4
- 239000000017 hydrogel Substances 0.000 description 4
- 238000002640 oxygen therapy Methods 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- 230000029663 wound healing Effects 0.000 description 4
- 230000015572 biosynthetic process Effects 0.000 description 3
- 239000003292 glue Substances 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 229910052757 nitrogen Inorganic materials 0.000 description 3
- 239000011780 sodium chloride Substances 0.000 description 3
- XKRFYHLGVUSROY-UHFFFAOYSA-N Argon Chemical compound [Ar] XKRFYHLGVUSROY-UHFFFAOYSA-N 0.000 description 2
- 239000007836 KH2PO4 Substances 0.000 description 2
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 description 2
- LHJQIRIGXXHNLA-UHFFFAOYSA-N calcium peroxide Chemical compound [Ca+2].[O-][O-] LHJQIRIGXXHNLA-UHFFFAOYSA-N 0.000 description 2
- 210000004027 cell Anatomy 0.000 description 2
- 239000002131 composite material Substances 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- 230000018109 developmental process Effects 0.000 description 2
- 229910000397 disodium phosphate Inorganic materials 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 238000012544 monitoring process Methods 0.000 description 2
- 229910000402 monopotassium phosphate Inorganic materials 0.000 description 2
- 239000008363 phosphate buffer Substances 0.000 description 2
- GNSKLFRGEWLPPA-UHFFFAOYSA-M potassium dihydrogen phosphate Chemical compound [K+].OP(O)([O-])=O GNSKLFRGEWLPPA-UHFFFAOYSA-M 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 238000007789 sealing Methods 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 239000004343 Calcium peroxide Substances 0.000 description 1
- 102000016938 Catalase Human genes 0.000 description 1
- 108010053835 Catalase Proteins 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 102000001554 Hemoglobins Human genes 0.000 description 1
- 108010054147 Hemoglobins Proteins 0.000 description 1
- SPAGIJMPHSUYSE-UHFFFAOYSA-N Magnesium peroxide Chemical compound [Mg+2].[O-][O-] SPAGIJMPHSUYSE-UHFFFAOYSA-N 0.000 description 1
- 239000004952 Polyamide Substances 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- 206010072170 Skin wound Diseases 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 229910052786 argon Inorganic materials 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 238000009530 blood pressure measurement Methods 0.000 description 1
- 230000010478 bone regeneration Effects 0.000 description 1
- 239000000872 buffer Substances 0.000 description 1
- 230000003139 buffering effect Effects 0.000 description 1
- 235000019402 calcium peroxide Nutrition 0.000 description 1
- MMCOUVMKNAHQOY-UHFFFAOYSA-N carbonoperoxoic acid Chemical compound OOC(O)=O MMCOUVMKNAHQOY-UHFFFAOYSA-N 0.000 description 1
- 239000003054 catalyst Substances 0.000 description 1
- 230000004663 cell proliferation Effects 0.000 description 1
- 238000010382 chemical cross-linking Methods 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 238000012790 confirmation Methods 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- LOKCTEFSRHRXRJ-UHFFFAOYSA-I dipotassium trisodium dihydrogen phosphate hydrogen phosphate dichloride Chemical group P(=O)(O)(O)[O-].[K+].P(=O)(O)([O-])[O-].[Na+].[Na+].[Cl-].[K+].[Cl-].[Na+] LOKCTEFSRHRXRJ-UHFFFAOYSA-I 0.000 description 1
- BNIILDVGGAEEIG-UHFFFAOYSA-L disodium hydrogen phosphate Chemical compound [Na+].[Na+].OP([O-])([O-])=O BNIILDVGGAEEIG-UHFFFAOYSA-L 0.000 description 1
- 238000010494 dissociation reaction Methods 0.000 description 1
- 230000005593 dissociations Effects 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 230000003179 granulation Effects 0.000 description 1
- 238000005469 granulation Methods 0.000 description 1
- 210000003714 granulocyte Anatomy 0.000 description 1
- 230000012010 growth Effects 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 239000001307 helium Substances 0.000 description 1
- 229910052734 helium Inorganic materials 0.000 description 1
- SWQJXJOGLNCZEY-UHFFFAOYSA-N helium atom Chemical compound [He] SWQJXJOGLNCZEY-UHFFFAOYSA-N 0.000 description 1
- 239000011261 inert gas Substances 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 229910052754 neon Inorganic materials 0.000 description 1
- GKAOGPIIYCISHV-UHFFFAOYSA-N neon atom Chemical compound [Ne] GKAOGPIIYCISHV-UHFFFAOYSA-N 0.000 description 1
- 230000037311 normal skin Effects 0.000 description 1
- 239000013307 optical fiber Substances 0.000 description 1
- 230000000242 pagocytic effect Effects 0.000 description 1
- 230000010412 perfusion Effects 0.000 description 1
- 150000002978 peroxides Chemical class 0.000 description 1
- 239000002953 phosphate buffered saline Substances 0.000 description 1
- 229920002647 polyamide Polymers 0.000 description 1
- 229920000515 polycarbonate Polymers 0.000 description 1
- 239000004417 polycarbonate Substances 0.000 description 1
- 229920000728 polyester Polymers 0.000 description 1
- 229920006324 polyoxymethylene Polymers 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 229920002635 polyurethane Polymers 0.000 description 1
- 239000004814 polyurethane Substances 0.000 description 1
- 239000001103 potassium chloride Substances 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 235000010413 sodium alginate Nutrition 0.000 description 1
- 239000000661 sodium alginate Substances 0.000 description 1
- 229940005550 sodium alginate Drugs 0.000 description 1
- SQSAJLXDUSFNKX-UHFFFAOYSA-M sodium;3-(prop-2-enoylamino)butane-2-sulfonate Chemical compound [Na+].[O-]S(=O)(=O)C(C)C(C)NC(=O)C=C SQSAJLXDUSFNKX-UHFFFAOYSA-M 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 230000006641 stabilisation Effects 0.000 description 1
- 238000011105 stabilization Methods 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 230000017423 tissue regeneration Effects 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
- 230000010388 wound contraction Effects 0.000 description 1
Abstract
The utility model discloses a kind of gels to discharge oxygen detection device, including open-top receptacle and can cover and the film of the oral area of closed open-top receptacle, open-top receptacle is equipped at least two entrances being in communication with the outside, and open-top receptacle is equipped with the oxygen measurement device of at least one detectable oxygen concentration or partial pressure of oxygen.The utility model has the advantages that the utility model proposes gel release oxygen detection device the oxygen rate of release and partial pressure of oxygen of gel can be quantitatively evaluated, influence of the oxygen to test result in tainer air can be excluded by being passed through buffer solution and gas, the detectable oxygen concentration of first oxygen measurement device or partial pressure of oxygen situation of change can calculate the oxygen rate of release of oxygen release gel by data analysis.The utility model relates to medical instruments fields.
Description
Technical field
The utility model relates to medical instruments field, in particular to a kind of gel discharges oxygen detection device.
Background technique
Oxygen therapy is more and more received and be applied in Wound healing and bone regeneration by clinic.With wound healing theory
Development, oxygen have obtained more and more confirmations for the positive influence of wound healing.Oxygen has weight for the healing of wound
It acts on.Studies have shown that oxygen can promote collage synthesis, fine cell Proliferation and new vascular generation in tissue regeneration processes, energy
Enhance granulocyte phagocytic function and promote granulation formation and Wound Contraction etc..Oxygen in air is not since partial pressure of oxygen is high, and one
The wound handled a bit often has covering, these all affect going deep into for oxygen, therefore air oxygen acts on less wound.
In recent years, enough research and clinical test show that topical oxygen therapy is the effective of raising wound healing
Method, it is some to be ground with response type oxygen release function, low cost and the material of oxygen being convenient for carrying or system
Study carefully exploitation, as CN104117057A " it is a kind of load enzyme the hydrogel composition with oxygen release function and its formation hydrogel "
A kind of disclosed oxygen release gel.
All oxygen therapies, including partial oxygen supply or hemoglobin are reinforced, can be to wound proximal end oxygen
Benefit in horizontal understanding.The partial pressure of oxygen of normal skin is usually 40mmHg, acute skin wound can drop to 30mmHg hereinafter,
And the partial pressure of oxygen of chronic wounds is down to 5mmHg.The partial pressure of oxygen near wound, i.e. transcutaneous oxygen pressure measurement (TCOM) are measured, is mesh
Before be considered measure wound oxygen content best Substitute Indexes.This measurement greatly depends on Multiple factors, including regional flow
Perfusion, thermotonus, the percutaneous diffusion of oxygen etc..
In oxygen therapy, oxygen rate of release and the partial pressure of oxygen for controlling oxygen releasing device are also very crucial.If release
Oxygen is too fast, can generate free radicals damaging cells.If oxygen release is excessively slow, enough energy cannot be provided to maintain cell to deposit
It is living.
In the prior art, not yet there is gel release oxygen detection device, technological deficiency is: can not be quantitatively evaluated solidifying
The oxygen rate of release and partial pressure of oxygen of glue, are unfavorable for the development and application of oxygen release gel.
Utility model content
The technical problem to be solved by the utility model is to provide a kind of gels to discharge oxygen detection device, can test oxygen release
The oxygen rate of release and partial pressure of oxygen of gel.
Used technical solution to solve above-mentioned technical problem: a kind of gel discharges oxygen detection device, including opening
It container and can cover and the film of the oral area of closed open-top receptacle, open-top receptacle is equipped at least two discrepancy being in communication with the outside
Mouthful, open-top receptacle is equipped with the oxygen measurement device of at least one detectable oxygen concentration or partial pressure of oxygen.
As an improvement, film is polyethylene film or polyvinyl chloride film.
As an improvement, oxygen measurement device includes the first oxygen measurement device and the second oxygen measurement device, the first oxygen
Measuring device can be placed in measurand, and the second oxygen measurement device can be placed in the inner cavity of open-top receptacle.
As an improvement, oxygen measurement device is oxygen sensor probes, oxygen sensor probes and external computer connect
It connects.
As an improvement, entrance include the first entrance and the second entrance, the first entrance be located at container side wall or
Bottom, the second entrance are located at the bottom of container.
As an improvement, the first entrance and the second entrance are hose connection, it is arranged with hose on hose connection, on hose
Equipped with can closed hose clip.
The utility model has the advantages that the utility model proposes gel release oxygen detection device can be quantitatively evaluated gel oxygen release
Rate and partial pressure of oxygen can exclude influence of the oxygen to test result in tainer air by being passed through buffer solution and gas,
The detectable oxygen concentration of first oxygen measurement device or partial pressure of oxygen situation of change can calculate oxygen release gel by data analysis
Oxygen rate of release.
Detailed description of the invention
The utility model is described further with reference to the accompanying drawing:
Fig. 1 is the structural schematic diagram of the detection device of the utility model embodiment；
Fig. 2 is the schematic diagram after the completion of the test method step (4) of the utility model embodiment；
Fig. 3 is the schematic diagram of test method step (5) intermediate state of the utility model embodiment；
Fig. 4 is the schematic diagram after the completion of the test method step (5) of the utility model embodiment；
Fig. 5 is the experimental data line chart of the utility model embodiment；
The noun and label that embodiment and Figure of description are related to include: open-top receptacle 1, film 2, the first entrance 3, the
Two entrances 4, clip 5, the first oxygen measurement device 6, the second oxygen measurement device 7, oxygen release gel 8.
Specific embodiment
Raw material used in embodiment unless otherwise specified, can be obtained from routine business approach.
Referring to figs. 1 to 4, a kind of gel discharges oxygen detection device, including open-top receptacle 1.It is solidifying for the ease of fixed oxygen release
Glue 8 and sealing open-top receptacle 1, open-top receptacle 1 are equipped with and can cover and the film 2 of the oral area of closed open-top receptacle 1.This implementation
Open-top receptacle 1 is rectangular glass guide channel in example.The shape of open-top receptacle 1 can be it is round, rectangular, cylindrical or other have one
The shape of constant volume and intensity.Open-top receptacle 1 can also be other chemical property stabilization and the material with some strength, including
But be not limited to polycarbonate, polyester, polyethylene, polypropylene, polyvinyl chloride, polyformaldehyde, polyurethane, polyamide etc..
In order to improve the leakproofness of open-top receptacle 1, the film 2 in the present embodiment is polyethylene film.Film 2 needs to have
Have air-locked property, should also be it is soft, so as to paste or bind open-top receptacle 1 oral area realize sealing.Film 2
Material can also be polyvinyl chloride film or other are airtight, with some strength and herein in test environment, chemical property is stablized
Other membrane materials.
Open-top receptacle 1 is passed in and out for the ease of buffer solution and gas, open-top receptacle 1 is equipped with the first entrance 3 and second
Entrance 4, the first entrance 3 and the second entrance 4 are located at the bottom of open-top receptacle 1 in the present embodiment.Second entrance 4 is located at
The bottom of open-top receptacle 1 can facilitate buffer solution to be discharged, and the first entrance 3 can also be provided on the side wall of open-top receptacle 1,
A possibility that buffer solution is flowed out from the first entrance 3 can be reduced.
For the ease of forming confined space between open-top receptacle 1 and film 2, the first entrance 3 and the second entrance 4 are
Hose connection, is arranged with hose on hose connection, hose be equipped with can closed hose clip 5.
When needing to be passed through or be discharged buffer solution or gas, clip 5 can be taken off.First entrance 3 and the second entrance 4
It can also be cone seal plug or screw lid.
For the ease of the oxygen concentration or partial pressure of oxygen in monitoring oxygen release gel 8 and confined space, film 2 is equipped with and can penetrate
The the first oxygen measurement device 6 and the second oxygen measurement device 7 of film 2.First oxygen measurement device 6 can be placed to oxygen release gel
In 8, the second oxygen measurement device 7 can be placed in confined space.First oxygen measurement device 6 and the second oxygen measurement device 7
It can be oxygen sensor probes, be mainly used for measuring the concentration or partial pressure of oxygen of oxygen gas in environment, according to measurement range
Difference and working life length, there are many model and product, such as German compact optical fiber formula oxygen measurement set FireSting
O2。
For the ease of the oxygen concentration or partial pressure of oxygen in real-time monitoring oxygen release gel 8 and confined space, the first oxygen measurement
Device 6 and the second oxygen measurement device 7 are equipped with USB interface, can be connect by USB line with external computer.Computer can
Record oxygen release gel 8 and oxygen concentration or partial pressure of oxygen in confined space in real time can calculate oxygen release gel 8 by data analysis
Oxygen rate of release.
The test process of the present embodiment is related to PBS buffer solution, PBS buffer solution (phosphate buffer
Saline) it is phosphate buffered saline solution, generally as solvent, plays dissolution protection reagent.It is in biochemical research
A kind of the most widely used buffer, main component Na2HPO4、KH2PO4, NaCl and KCl, due to Na2HPO4And KH2PO4
They have second level dissociation, and the pH value range of buffering is very wide.
A kind of gel release oxygen test method based on above-mentioned detection device, comprising the following steps:
(1) oxygen release gel 8 is fixed on film 2；
(2) film 2 is penetrated with the first oxygen measurement device 6 and be inserted into its probe in oxygen release gel 8, with the second oxygen
Measuring device 7 penetrates film 2 and oxygen release gel 8, and the probe of the second oxygen measurement device 7 is made to be pierced by oxygen release gel 8；
(3) by the covering of above-mentioned film 2, simultaneously adhesive seal is fixed on oxygen release gel 8 spacious in the oral area of open-top receptacle 1
The oral area of mouth container 1, is presented to the probe of the second oxygen measurement device 7 in the inner cavity of open-top receptacle 1；
(4) overturning open-top receptacle 1 and makes the first entrance 3 and the second entrance 4 upward, removes the first entrance 3 and the
Clip 5 on two entrances 4 injects PBS buffer solution into the first entrance 3, until the air in open-top receptacle 1 is complete
Discharge；
(5) it overturns open-top receptacle 1 and makes the second entrance 4 downward, inject nitrogen into the first entrance 3, make in container
PBS buffer solution be discharged from the second entrance 4, until the PBS buffer solution in open-top receptacle 1 is fully drained, use folder
Son 5 closes the first entrance 3 and the second entrance 4, makes to keep air-tight state in open-top receptacle 1；
(6) oxygen concentration or partial pressure of oxygen of the first oxygen test device and the second oxygen test device are recorded by computer
Situation of change.
(7) test period of the first oxygen measurement device 6 and the second oxygen measurement device 7 is set as 20min, when the first oxygen
When the sequential growth rate of oxygen concentration or partial pressure of oxygen that gas measuring device 6 and the second oxygen measurement device 7 measure is not more than 1%,
Test terminates.
The utility model proposes gel release oxygen test method and detection device the oxygen of gel can be quantitatively evaluated and release
Rate and partial pressure of oxygen are put, the oxygen in tainer air can be excluded to the shadow of test result by being passed through buffer solution and gas
It rings, the detectable oxygen concentration of the first oxygen measurement device 6 or partial pressure of oxygen situation of change, oxygen release can be calculated by data analysis
The oxygen rate of release of gel 8.
Oxygen release gel 8 in this test can be gel rubber material perhaps gel rubber material composition gel rubber material or gel
Material compositions are a kind of gel rubber materials that can discharge oxygen, can be embedding or adsorption of oxygen (such as perfluocarbon and blood red
Protein carrier) oxygen carrying type gel or the raw oxygen type gel of chemistry (be placed in oxygen generating agent in such as dressing system -- mainly peroxide
With inorganic peroxide salt such as percarbonic acid, calper calcium peroxide, peromag or catalyst, chemistry occurs using hydrogen peroxide and water
One of oxygen is resolved into reaction).This test method and detection device have the wider scope of application.
Buffer solution in order to exclude influence of the oxygen in the air in open-top receptacle 1 to test result, in step (5)
For PBS (phosphate buffer saline) buffer solution, the gas in step (5) is nitrogen.PBS buffer solution may be used also
It is replaced with the buffer solution for using other chemical property under this test condition stable, nitrogen can also use other in this test
Under the conditions of the stable inert gas (such as helium, neon or argon gas) of chemical property replace.According to the oxygen release speed of oxygen release gel 8
Difference, the test period of settable different the first oxygen measurement device 6 and the second oxygen measurement device 7.Oxygen release speed is faster,
Test period can be set to shorter, set reasonable test period, it is ensured that test result accurate and accelerating as far as possible test into
Degree.
The following are an experimental results of the present embodiment:
This experiment is prepared for poly- (2- acrylamido-methyl propane sulfonic acid sodium salt) (PAMPSNa) water-setting by chemical crosslinking
Glue and PAMPSNa- sodium alginate composite hydrogel, after changing composite hydrogel load catalase and hydrogen peroxide, system energy
The release oxygen of continuous and effective.The measurement for being carried out oxygen release to the gel rubber system using the method for the present embodiment, is obtained a result
As shown in Figure 5.The test period of this experiment is set as 20min, show that system reaches flat in 300min or so from experimental result
Weighing apparatus, in order to which further identity system has reached balance, this test acquires several groups of data again after 300min.
The experimental data of the present embodiment:
| Time (minute) | 20 | 40 | 60 | 80 | 100 | 120 | 140 | 160 | 180 |
| PO2(mmHg) | 18 | 42 | 78 | 105 | 123 | 138 | 147 | 150 | 152 |
| Time (minute) | 220 | 240 | 260 | 300 | 340 | 400 | 450 | 500 | 550 |
| PO2(mmHg) | 154 | 155 | 157 | 159 | 159 | 159 | 159 | 159 | 159 |
The embodiments of the present invention is explained in detail above in conjunction with attached drawing, but the utility model is not limited to
State embodiment, technical field those of ordinary skill within the scope of knowledge, can also do not depart from it is practical
Various changes can be made under the premise of novel objective.
Claims (6)
1. a kind of gel discharges oxygen detection device, it is characterised in that: including open-top receptacle and can cover and closed open-top receptacle
Oral area film, open-top receptacle be equipped at least two entrances being in communication with the outside, open-top receptacle be equipped at least one
The oxygen measurement device of detectable oxygen concentration or partial pressure of oxygen.
2. gel according to claim 1 discharges oxygen detection device, it is characterised in that: the film is polyethylene film
Or polyvinyl chloride film.
3. gel according to claim 1 discharges oxygen detection device, it is characterised in that: the oxygen measurement device includes
First oxygen measurement device and the second oxygen measurement device, the first oxygen measurement device can be placed in measurand, the second oxygen
Measuring device can be placed in the inner cavity of open-top receptacle.
4. gel according to claim 1 discharges oxygen detection device, it is characterised in that: the oxygen measurement device is oxygen
Gas sensor probe, oxygen sensor probes are connect with external computer.
5. gel according to claim 1 discharges oxygen detection device, it is characterised in that: the entrance goes out including first
Entrance and the second entrance, the first entrance are located at side wall or the bottom of container, and the second entrance is located at the bottom of container.
6. gel according to claim 5 discharges oxygen detection device, it is characterised in that: first entrance and second
Entrance is hose connection, is arranged with hose on hose connection, hose be equipped with can closed hose clip.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820976889.0U CN208780672U (en) | 2018-06-22 | 2018-06-22 | A kind of gel release oxygen detection device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820976889.0U CN208780672U (en) | 2018-06-22 | 2018-06-22 | A kind of gel release oxygen detection device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN208780672U true CN208780672U (en) | 2019-04-23 |
Family
ID=66152664
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201820976889.0U Active CN208780672U (en) | 2018-06-22 | 2018-06-22 | A kind of gel release oxygen detection device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN208780672U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108896712A (en) * | 2018-06-22 | 2018-11-27 | 广东省医疗器械研究所 | A kind of gel release oxygen test method and detection device |
-
2018
- 2018-06-22 CN CN201820976889.0U patent/CN208780672U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108896712A (en) * | 2018-06-22 | 2018-11-27 | 广东省医疗器械研究所 | A kind of gel release oxygen test method and detection device |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP3901781B2 (en) | Calibration method of gas concentration measurement sensor | |
| Gray et al. | Determination of the oxyhaemoglobin dissociation curves for mouse and rat blood | |
| CA1305913C (en) | Tissue equivalent test systems | |
| CN110121312A (en) | With or without the system of the containment device with oxygen sensor of external source oxygen conveying | |
| Cohen et al. | Models of wound healing | |
| EP0522286A1 (en) | Device and methods for controlled diffusion of a chemical substance | |
| CN208780672U (en) | A kind of gel release oxygen detection device | |
| Rofstad et al. | Growth characteristics of human melanoma multicellular spheroids in liquid‐overlay culture: comparisons with the parent tumour xenografts | |
| CN108896712A (en) | A kind of gel release oxygen test method and detection device | |
| Ruiz‐Espigares et al. | Evolution of Metastasis Study Models toward Metastasis‐On‐A‐Chip: The Ultimate Model? | |
| CN101158676B (en) | Analysis method and device for evaluating blood and crucifixes oxygen carrying and oxygen releasing function thereof | |
| CN108918451B (en) | Real-time detection and dynamic intervention device and test intervention method for cell metabolism | |
| JP4248744B2 (en) | Planar biosensor with microstructure, method of using the same, and method of immobilizing biocatalyst | |
| Chakrabarti et al. | Effects of age on fibrinolytic activity and factors V, VII and VIII | |
| Hahn | Techniques for measuring the partial pressures of gases in the blood. I. In vitro measurements | |
| CN104459145A (en) | Cosmetic detection | |
| CN102967543A (en) | Method for measuring permeability coefficient of oral drug by using hollow fiber membrane | |
| CN107121413B (en) | Blood sample providing device, platelet aggregation function detector and platelet aggregation function detection method | |
| US10114010B1 (en) | Biomimetic interface device and methods of using the same | |
| Hwang et al. | Evaluation of the paratrend multi-analyte sensor for potential utilization in long-duration automated cell culture monitoring | |
| CN115960818B (en) | Preparation method and application of recombinant human 3D skin model | |
| US11965876B1 (en) | Biomimetic interface device and methods of using the same | |
| CN103041453A (en) | Double-layer skin covering material compositely built by collagen/fibrin glue-VEGF (vascular endothelial growth factor) and mesenchymal stem cell as well as preparation method and application of double-layer skin covering material | |
| CN211921592U (en) | Three-dimensional lung cancer cell culture ware | |
| RU2679887C2 (en) | Method for obtaining materials for high-hydrophilic coating of hemocompatible membranes |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CP01 | Change in the name or title of a patent holder |
Address after: No. 1307, Guangzhou Avenue middle, Tianhe District, Guangzhou, Guangdong 510500 Patentee after: Institute of health medicine, Guangdong Academy of Sciences Address before: No. 1307, Guangzhou Avenue middle, Tianhe District, Guangzhou, Guangdong 510500 Patentee before: GUANGDONG INSTITUTE OF MEDICAL INSTRUMENTS |
|
| CP01 | Change in the name or title of a patent holder | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20231121 Address after: No.10, shiliugang Road, Haizhu District, Guangzhou City, Guangdong Province 510000 Patentee after: Institute of biological and medical engineering, Guangdong Academy of Sciences Address before: No. 1307, Guangzhou Avenue middle, Tianhe District, Guangzhou, Guangdong 510500 Patentee before: Institute of health medicine, Guangdong Academy of Sciences |
|
| TR01 | Transfer of patent right |