CN208701078U - A kind of magnetic frame - Google Patents

A kind of magnetic frame Download PDF

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Publication number
CN208701078U
CN208701078U CN201820870423.2U CN201820870423U CN208701078U CN 208701078 U CN208701078 U CN 208701078U CN 201820870423 U CN201820870423 U CN 201820870423U CN 208701078 U CN208701078 U CN 208701078U
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CN
China
Prior art keywords
plate
hole
centrifuge tube
risers
magnet plate
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201820870423.2U
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Chinese (zh)
Inventor
刘继来
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Individual
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Individual
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Publication date
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Priority to CN201820870423.2U priority Critical patent/CN208701078U/en
Application granted granted Critical
Publication of CN208701078U publication Critical patent/CN208701078U/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Abstract

The utility model discloses a kind of magnetic frames, including left risers, right risers and magnet plate, upper plate and lower plate are horizontally arranged between the left risers and right risers, multiple first circular holes are provided in the plate face of the upper plate, the first open slot of left and right directions is provided in the middle part of the upper plate lower end surface, the second open slot of left and right directions is provided in the middle part of the lower plate upper surface, the magnet plate is inserted into the first open slot and the second open slot by first through hole, and the right end of the magnet plate is extend out to outside first through hole;Left risers, right risers, upper plate and the lower plate of the utility model setting form centrifuge tube shelf, when carrying out being purified by flash reaction using centrifuge tube, magnet plate is not installed, when carrying out waste liquid removal and impurity elimination, magnet plate is mounted on centrifuge tube shelf, centrifuge tube shelf becomes magnetic frame, does not need the reciprocating rotary between magnetic frame and centrifuge tube shelf during the experiment and moves centrifuge tube, experimental period can be made full use of, experiment fault rate will not improve.

Description

A kind of magnetic frame
Technical field
The utility model relates to molecular biology field, specifically a kind of magnetic frame.
Background technique
Magnetic frame is the necessary devices that nanometer magnetic bead method extracts nucleic acid.Nanometer magnetic bead adsorbed target substance, passes through magnetic frame Nanometer magnetic bead is concentrated to the position for being adsorbed on and leaning near magnet in centrifuge tube, may be implemented quickly to be separated by solid-liquid separation, remove deimpurity mesh , facilitate target substance recycling acquisition.Magnetic frame is also applied to test using the related protein group of nanometer magnetic bead at present In.
The magnetic frame that related experiment uses both at home and abroad at present is the integrally formed structure of traditional I-shaped, and upper end is Centrifuge tube card slot, lower end are the pedestal with counterweight, and vertical leg embeds magnet, magnetic bead can be adsorbed to centrifuge tube side wall or bottom Portion.The popularization and application of the traditional structure, to proteomic experiments operation band convenience.Such structure has the following disadvantages, Since magnet is the inside for being embedded in vertical leg, and magnetic frame ontology is integrally formed structures, as long as leading to centrifuge tube It is placed in card slot, the magnetic bead in centrifuge tube will be attracted to the position that near magnet is leaned in centrifuge tube, but magnetic bead needs It mixes, elute repeatedly in different liquids, purifying removal impurity, being purified by flash reaction and need the centrifuge tube shelf in no magnetic force enterprising Row, and waste liquid removes and needs to carry out on magnetic frame, causes back and forth to shift between magnetic frame and centrifuge tube shelf in experimentation Centrifuge tube not only wastes experimental period, and fault rate is be easy to cause to improve.
Utility model content
The purpose of this utility model is to provide a kind of magnetic frames, to solve to need in experimentation in magnetic frame and centrifugation The problem of reciprocating rotary moves centrifuge tube between pipe support, causes to waste experimental period, and fault rate is be easy to cause to improve.
To achieve the above object, the utility model provides the following technical solutions: a kind of magnetic frame, including left risers, the right side are stood Plate and magnet plate, are horizontally arranged with upper plate and lower plate between the left risers and right risers, in the plate face of the upper plate Multiple first circular holes are provided with, the first open slot of left and right directions, the lower plate are provided in the middle part of the upper plate lower end surface It is provided with the second open slot of left and right directions in the middle part of part upper surface, is provided with first through hole in the middle part of the right risers, it is described Magnet plate includes rectangular slab and the magnetite that is embedded in rectangular slab, and the magnet plate is inserted into the first open slot and the by first through hole In two open slots, the right end of the magnet plate is extend out to outside first through hole.
Preferably, it is provided with multiple second circular holes on the lower plate, multiple third circular holes are provided in the right risers, The size of first circular hole, the second circular hole and third circular hole is all different.
Preferably, annular groove, the ring are provided on the hole wall of first circular hole, the second circular hole and third circular hole Rubber ring is installed on connected in star.
Preferably, the junction of first through hole is provided with elastic clamping sheet on the magnet plate.
Preferably, the upper end of the magnet plate is provided with semi-circular recesses, is provided with that lead to first recessed on the upper plate The through-hole of slot is equipped with spring in the through-hole, and the lower spring end is fixedly connected with bead, and the bead extends to semicircle In connected in star.
Preferably, the magnet plate, which is located in the plate face on the outside of right risers, is provided with the second through-hole.
Compared with prior art, the utility model has the beneficial effects that
1, left risers and right risers are provided with, upper plate and lower plate are horizontally arranged between left risers and right risers, it is left Vertical plate, right risers, upper plate and lower plate form centrifuge tube shelf, are provided with circular hole on right risers, upper plate and lower plate, can incite somebody to action Centrifuge tube is placed on these circular holes, when carrying out being purified by flash reaction using centrifuge tube, is not installed magnet plate, is carried out waste liquid removal When with impurity elimination, magnet plate is mounted on centrifuge tube shelf, centrifuge tube shelf becomes magnetic frame, under the action of magnetite, by centrifuge tube In nanometer magnetic bead concentrate be adsorbed in centrifuge tube close to magnetite position, may be implemented quickly to be separated by solid-liquid separation, go deimpurity Purpose does not need the reciprocating rotary between magnetic frame and centrifuge tube shelf and moves centrifuge tube, during the experiment when can make full use of experiment Between, experiment fault rate will not improve.
2, it is provided with annular groove on the hole wall of the first circular hole, the second circular hole and third circular hole, is installed on annular groove There is rubber ring, rubber ring can fix the centrifuge tube being placed in circular hole stronger.
Detailed description of the invention
Fig. 1 is the main view of the structural schematic diagram of the utility model.
Fig. 2 is the top view of the structural schematic diagram of the utility model.
Fig. 3 is the rearview of the structural schematic diagram of the utility model.
Fig. 4 is the right view of the structural schematic diagram of the utility model.
Fig. 5 is the first structural schematic diagram of magnet plate.
Fig. 6 is second of structural schematic diagram of magnet plate
The structural schematic diagram that Fig. 7 is magnet plate when being second of structure with bead cooperation clamping.
In figure: 1- left risers, 2- right risers, 21- third circular hole, 3- upper plate, the first circular hole of 31-, 4- lower plate, 41- Second circular hole, 5- magnet plate, 51- rectangular slab, 52- magnetite, the second through-hole of 53-, 54- semi-circular recesses, 6- rubber ring, 7- elasticity Clamping sheet, 8- bead.
Specific embodiment
The following will be combined with the drawings in the embodiments of the present invention, carries out the technical scheme in the embodiment of the utility model Clearly and completely describe, it is clear that the described embodiments are only a part of the embodiments of the utility model, rather than whole Embodiment.Based on the embodiments of the present invention, those of ordinary skill in the art are without making creative work Every other embodiment obtained, fall within the protection scope of the utility model.
Please refer to Fig. 1, Fig. 2, Fig. 3, Fig. 4, Fig. 5, Fig. 6 and Fig. 7, in the utility model embodiment, a kind of magnetic frame, including Left risers 1, right risers 2 and magnet plate 5, are horizontally arranged with upper plate 3 and lower plate 4, Zuo Li between left risers 1 and right risers 2 Plate 1, right risers 2, upper plate 3 and lower plate 4 form centrifuge tube shelf, are provided with multiple first circular holes 31 in the plate face of upper plate 3, For placing centrifuge tube, the first open slot of left and right directions is provided in the middle part of 3 lower end surface of upper plate, 4 upper surface of lower plate Middle part is provided with the second open slot of left and right directions, and the middle part of right risers 2 is provided with first through hole, and magnet plate 5 includes rectangular slab 51 and the magnetite 52 that is embedded in rectangular slab 51, magnet plate 5 be inserted into the first open slot and the second open slot by first through hole, magnetic The right end of slabstone 5 is extend out to outside first through hole, when carrying out being purified by flash reaction using centrifuge tube, is not installed magnet plate 5, is carried out useless When liquid is removed with impurity elimination, magnet plate 5 is inserted into the first open slot and the second open slot, centrifuge tube shelf becomes magnetic frame, in magnetic Under the action of stone 52, the nanometer magnetic bead in centrifuge tube is concentrated to the position being adsorbed in centrifuge tube close to magnetite 52, may be implemented It is quickly separated by solid-liquid separation, goes deimpurity purpose, do not need back and forth to shift between magnetic frame and centrifuge tube shelf during the experiment Centrifuge tube, can make full use of experimental period, and experiment fault rate will not improve;Multiple second circular holes are provided on lower plate 4 41, it is provided with multiple third circular holes 21 in right risers 2, the second circular hole 41 and third circular hole 21 are also used for placing centrifuge tube, and first The size of circular hole 31, the second circular hole 41 and third circular hole 21 is all different, and can be used for placing the centrifuge tube of different size, than Such as, make first through hole 31 for placing the centrifuge tube of 2ML, make the second through-hole 41 for placing the centrifuge tube of 1.5ML, keep third logical Hole 21 is used to place the centrifuge tube of 15ML;Ring is provided on the hole wall of first circular hole 31, the second circular hole 41 and third circular hole 21 Connected in star, is equipped with rubber ring 6 on annular groove, and rubber ring 6 can be by fixed stronger of the centrifuge tube being placed in circular hole;Magnetic Elastic clamping sheet 7 is provided on slabstone 5 with the junction of first through hole, makes magnet plate 5 and first through hole clamping, by magnet plate 5 It firmly installs, this is a kind of clamping structure of magnet plate 5;The upper end of magnet plate 5 is provided with semi-circular recesses 54, on upper plate 3 It is provided with the through-hole for leading to the first groove, spring is installed in through-hole, lower spring end is fixedly connected with bead 8, and bead 8 is stretched Into semi-circular recesses 54, magnet plate 5 is firmly installed, this is second of clamping structure of magnet plate 5;Magnet plate 5 is located at the right side It is provided with the second through-hole 53 in the plate face in 2 outside of vertical plate, magnet plate 5 and first through hole clamping under the action of elastic clamping sheet 7, It is not easily taken out, finger can be protruded into the second through-hole 53, magnet plate 5 is pulled out.
It is obvious to a person skilled in the art that the present invention is not limited to the details of the above exemplary embodiments, and And without departing substantially from the spirit or essential attributes of the utility model, it can realize that this is practical new in other specific forms Type.Therefore, in all respects, the present embodiments are to be considered as illustrative and not restrictive, this is practical new The range of type is indicated by the appended claims rather than the foregoing description, it is intended that containing for the equivalent requirements of the claims will be fallen in All changes in justice and range are embraced therein.It should not treat any reference in the claims as limiting Related claim.

Claims (6)

1. a kind of magnetic frame, including left risers (1), right risers (2) and magnet plate (5), it is characterised in that: the left risers (1) It is horizontally arranged with upper plate (3) and lower plate (4) between right risers (2), is provided in the plate face of the upper plate (3) multiple First circular hole (31) is provided with the first open slot of left and right directions, the lower plate in the middle part of upper plate (3) lower end surface (4) it is provided with the second open slot of left and right directions in the middle part of upper surface, is provided with first through hole in the middle part of the right risers (2), The magnet plate (5) includes rectangular slab (51) and the magnetite (52) being embedded in rectangular slab (51), and the magnet plate (5) is by first Through-hole is inserted into the first open slot and the second open slot, and the right end of the magnet plate (5) is extend out to outside first through hole.
2. a kind of magnetic frame according to claim 1, it is characterised in that: be provided with multiple second on the lower plate (4) Circular hole (41) is provided with multiple third circular holes (21), first circular hole (31), the second circular hole (41) on the right risers (2) It is all different with the size of third circular hole (21).
3. a kind of magnetic frame according to claim 2, it is characterised in that: first circular hole (31), the second circular hole (41) It is provided with annular groove on the hole wall of third circular hole (21), rubber ring (6) are installed on the annular groove.
4. a kind of magnetic frame according to claim 1, it is characterised in that: the company on the magnet plate (5) with first through hole The place of connecing is provided with elastic clamping sheet (7).
5. a kind of magnetic frame according to claim 1, it is characterised in that: the upper end of the magnet plate (5) is provided with semicircle Connected in star (54) is provided with the through-hole for leading to the first groove on the upper plate (3), spring is equipped in the through-hole, described Lower spring end is fixedly connected with bead (8), and the bead (8) extends in semi-circular recesses (54).
6. a kind of magnetic frame according to claim 1, it is characterised in that: the magnet plate (5) is located on the outside of right risers (2) Plate face on be provided with the second through-hole (53).
CN201820870423.2U 2018-06-06 2018-06-06 A kind of magnetic frame Expired - Fee Related CN208701078U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201820870423.2U CN208701078U (en) 2018-06-06 2018-06-06 A kind of magnetic frame

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201820870423.2U CN208701078U (en) 2018-06-06 2018-06-06 A kind of magnetic frame

Publications (1)

Publication Number Publication Date
CN208701078U true CN208701078U (en) 2019-04-05

Family

ID=65934889

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201820870423.2U Expired - Fee Related CN208701078U (en) 2018-06-06 2018-06-06 A kind of magnetic frame

Country Status (1)

Country Link
CN (1) CN208701078U (en)

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CF01 Termination of patent right due to non-payment of annual fee
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20190405

Termination date: 20200606