CN208693250U - A kind of ophthalmology high speed, high resolution multifunctional optical coherence tomography device based on slit-lamp platform - Google Patents
A kind of ophthalmology high speed, high resolution multifunctional optical coherence tomography device based on slit-lamp platform Download PDFInfo
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- CN208693250U CN208693250U CN201720880110.0U CN201720880110U CN208693250U CN 208693250 U CN208693250 U CN 208693250U CN 201720880110 U CN201720880110 U CN 201720880110U CN 208693250 U CN208693250 U CN 208693250U
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Abstract
The utility model discloses a kind of ophthalmology high speed, high resolution multifunctional optical coherence tomography device based on slit-lamp platform, computer including the OCT image optical path being arranged on slit-lamp platform and for receiving OCT image optical path signal, the OCT image optical path includes light source, to scan the sample arm of eyeball and generate the reference arm of interference light with sample arm, the sample arm and reference arm receive the light that light source issues, the reference arm includes lens group, the lens group includes the first lens and the plane mirror positioned at the separate light inlet side of lens, the lens group of the reference arm is able to carry out switching, first lens of the different lens groups of switching are different with the relative position of plane mirror.The device adjusts the depth of focus by switching different lens group can be realized three-dimensional imaging to anterior chamber of eye and posterior segment on the apparatus.
Description
Technical field
The utility model belongs to optical imaging field, and in particular to a kind of ophthalmology high speed and high resoltuion based on slit-lamp platform
Rate multifunctional optical coherence tomography device.
Background technique
In recent years, statistics shows that ophthalmology disease has become and endangers human health and life quality, after tumour, cardiovascular disease
Third position disease later.Early detection, the early diagnosis of ophthalmology disease are the premise and basis correctly treated, and eyeball is made
It is the ideal target organ based on optical detection principle imaging technique for the optics organ of precise structure.
With the rapid development of ophthalmology imaging technique in recent years, relevant scanning (the Optical Coherence of optical fault
Tomography, OCT) this contactless, Noninvasive novel ophthalmology diagnostic techniques appearance and development, be ophthalmology disease
Diagnosing and treating provide important information, Morphological measurement function has been applied to tear film, epithelium, anterior chamber, crystalline lens
And in the rigorous analysis of retinal function, the existing Diagnosis-treat Model of ophthalmology is changed, in ophthalmology of being known as diagnostic techniques
Journey upright stone tablet formula achievement.
The commercially use OCT functions of the equipments of existing eye examination are more single, and what is had can only be directed to the cornea etc. of anterior chamber of eye
Eyeball tissue, what is had can only be imaged for institutional frameworks such as posterior segment retinas.Although incorporating anterior chamber of eye, back segment there are some
The technical solution of imaging, but the disadvantages of there is structure is complicated, inconvenient, lack it is a kind of have it is certain check comfort level,
Simple and fast, structure section gathers, easy to operate imaging scheme.
Utility model content
It is relevant disconnected that the main purpose of the utility model is to provide a kind of ophthalmology multifunctional opticals based on slit-lamp platform
Layer imaging device, can complete the high speed to patient's anterior chamber of eye and posterior segment, high-resolution imaging on the apparatus.
To achieve the above objectives, the technical solution adopted in the utility model are as follows: a kind of ophthalmology based on slit-lamp platform is more
Function optical coherence tomographic imaging apparatus, including the OCT image optical path being arranged on slit-lamp platform and for receiving OCT image
The computer of optical path signal, the OCT image optical path include light source, the sample arm to scan eyeball and generate with sample arm dry
The reference arm of light is related to, the sample arm and reference arm receive the light that light source issues, and the reference arm includes lens group, the lens
Group includes the first lens and the plane mirror positioned at the separate light inlet side of lens, which is characterized in that the reference arm
Lens group is able to carry out switching, and the first lens of the different lens groups of switching and the relative position of plane mirror are different.
Preferably, the reference arm further includes the slit for being used to adjust light-inletting quantity being arranged at the light inlet of reference arm.
Preferably, the sample arm include 2-D vibration mirror system to scan eyeball and setting 2-D vibration mirror system with
Between eyeball and the second lens moving up and down.
Preferably, the sample arm further includes being arranged between the second lens and eyeball and dismountable eyepiece.
Preferably, the sample arm further includes the fixation system of aid imaging, and the fixation system includes to eyeball
The target display screen being fixed, the target display screen are connect with Computer signal.
Preferably, the fixation system further includes the auxiliary positioning camera connecting with Computer signal, the auxiliary positioning
Camera can be acquired outside hole by sample and be shot.
It preferably, further include the spectrometer handled the interference light that sample arm and reference arm generate.
It preferably, further include the high speed linear array CCD camera being connected between spectrometer and computer.
Compared with prior art, the utility model has the following beneficial effects:
1) the utility model imaging system by switching lens group adjust optical path, make imaging system to anterior chamber of eye, back segment not
It is focused with position, realizes the Multifunctional imaging of anterior chamber of eye, back segment；
2) the fixation system of the area of computer aided imaging of the utility model design, and it is integrated in slit-lamp platform, lead to
It crosses auxiliary positioning camera and realizes adjusting to just, then by computer to target for patient's eyeball, facilitate the view of fixed those who are investigated
Line, so that operator is to patient's eyeball fast imaging；
3) by using high speed linear array CCD camera, the acquisition, processing, efficiency of transmission of image can be improved, greatly improve
Detection efficiency realizes ultrahigh resolution, high speed imaging.
Detailed description of the invention
Fig. 1 be a kind of ophthalmology multifunctional optical coherence tomography device based on slit-lamp platform of the utility model at
As schematic diagram
Fig. 2 is a kind of master of the ophthalmology multifunctional optical coherence tomography device based on slit-lamp platform of the utility model
View
After Fig. 3 is a kind of ophthalmology multifunctional optical coherence tomography device eye based on slit-lamp platform of the utility model
Section imaging pattern reference arm light path schematic diagram
After Fig. 4 is a kind of ophthalmology multifunctional optical coherence tomography device eye based on slit-lamp platform of the utility model
Section imaging pattern sample arm light path schematic diagram
Fig. 5 be a kind of ophthalmology multifunctional optical coherence tomography device based on slit-lamp platform of the utility model at the moment
Section imaging pattern reference arm light path schematic diagram
Fig. 6 be a kind of ophthalmology multifunctional optical coherence tomography device based on slit-lamp platform of the utility model at the moment
Section imaging pattern sample arm light path schematic diagram
Specific embodiment
It is described below for disclosing the utility model so that those skilled in the art can be realized the utility model.It retouches below
Preferred embodiment in stating is only used as illustrating, it may occur to persons skilled in the art that other obvious modifications.
As illustrated in fig. 1 and 2, a kind of ophthalmology multifunctional optical coherence tomography device based on slit-lamp platform 11, institute
Stating slit-lamp platform 11 is by the slit-lamp microscope of repacking, and the imaging device includes light source 1, the light that can emit laser
Fine coupling device 2, reference arm, sample arm, spectrometer and the computer for carrying out image analysis.The light source 1 passes through optical fiber and light
Fine coupling device 2 connects, and the reference arm and sample arm pass through optical fiber respectively and connect with fiber coupling device 2, the spectrometer
Light inlet connect with fiber coupling device 2 by optical fiber, the signal output end of the spectrometer passes through high speed linear array CCD camera
4 connect with Computer signal.Wherein, spectrometer, high speed linear array CCD camera 4 are all made of the prior art.
The reference arm includes lens barrel and the lens group that is threadedly coupled with lens barrel, is provided in the light inlet of lens barrel adjustable narrow
L1 is stitched, the lens group can be focused and reflect to the light from adjustable slit L1, and specifically, the lens group includes saturating
Mirror L2 and plane mirror M, the lens L2 are convex lens, and specifically, the specification of lens L2 and plane mirror M all use
The prior art, and will not be described here in detail.
To enable imaging system to have the different depths of focus, the lens group of the reference arm is changeable, and different is saturating
The relative position of lens L2/L3 and plane mirror M1/M2 Bu Tong can reach the different depths of focus in turn in microscope group, specifically
Depth of focus when being closer of ground, lens L2/L3 and plane mirror M1/M2 are shallower, distance farther out when the depth of focus it is deeper.
The sample arm includes the 2-D vibration mirror system 9 being arranged in optical path, the 2-D vibration mirror system 9 receive it is sharp
Eyeball is scanned after light.The 2-D vibration mirror system 9 uses the prior art, and and will not be described here in detail.
The sample arm further includes multiple lens L6, L7, the L8 (being convex lens) and eyepiece 8 being arranged in optical path,
It can be realized the adjusting to optical path by lens L6, L7, L8 and eyepiece 8, and the eyepiece 8 is arranged in 2-D vibration mirror system
It, specifically, can be by eyepiece 8 by being magnetically attached to the suitable position of slit-lamp platform, the lens between 9 and eyeball 10
L6, L7 and L8 be individually positioned in 2-D vibration mirror system 9 before, between 2-D vibration mirror system 9 and eyepiece 8 and eyepiece 8 and eyeball
Between 10, and the position of the quantity of lens and setting can be adjusted as needed.Described lens L6, L7, L8 and mesh
The specification of mirror 8 uses the prior art, and and will not be described here in detail.
It is additionally provided with laser aligner 6 in the light inlet of the sample arm, the laser aligner 6 uses the prior art,
And will not be described here in detail.
The spectrometer includes collimating mirror L4, grating 3 and lens L5, spectrometer and collimating mirror L4, grating 3 and lens L5
It is all made of the prior art, and will not be described here in detail.What the light and sample arm that reference arm returns returned has sample tissue information (eyeball
Information) light interfere after enter spectrometer, the interference light with sample tissue information after interfering is in spectrum
It carries out passing through high speed linear array CCD camera 4 and entering after frequency domain Fourier transformation in instrument carrying out processing imaging in computer.
The sample arm further includes the fixation system of aid imaging, and the fixation system is swept to the eyeball to patient
Eyeball is fixed when retouching imaging and eyeball is directed at sample arm.
The fixation system includes showing to display target target target display screen 5 and auxiliary positioning camera 7, the target
Screen 5 and auxiliary positioning camera 7 are connect with Computer signal, the display of the target display screen 5 is counted by the control of computer
Calculation machine can control target in the display position of target display screen 5, when scanning eyeball, control target in target by computer
Position on display screen 5, then eyeball keeps a close watch on target to realize that eyeball is fixed.
In ocular imaging, need for be fixed on head on the location structure 13 of slit-lamp platform, since sample arm is close
One end of eyeball is a certain size sample acquisition hole, there is no assurance that the head of all people is placed on location structure 13,
Eyeball can just be directed at sample acquisition hole, this just needs to be adjusted the position of location structure, the location structure 13
Adjustment is controlled by operating stick 12, location structure 13 can be made to move in perpendicular by control-rod 12.In the mistake of adjustment
Cheng Zhong, the auxiliary positioning camera 7 acquires the position that hole shoots head by sample, and auxiliary positioning camera 7 is by shooting
Photo is transferred back in computer in real time and is shown in computer screen, and operator can be according to the photo passed back in real time
The position that location structure 13 is adjusted by operation control-rod 12 is aligned until eyeball acquires hole with sample.Wherein, the operation
Bar 12 and location structure 13 are a part of slit-lamp platform, belong to the prior art, and will not be described here in detail.
When in use, calibration is carried out to sample arm by fixation system first and patient's sight is fixed: is flat using slit-lamp
The positioning device 13 of platform fixes patients head, the auxiliary positioning camera 7 and target display screen 5 of fixation system is opened, according to auxiliary
The live-pictures of positioning camera 7 are helped to indicate, operation 12 running fix structure 13 of operating stick makes eyeball 10 enter 2-D vibration mirror system 9
Scanning range completes system calibration and patient's sight is fixed by making patient watch the target display screen 5 of computer control attentively；It beats
Open the light the sending of source 1 laser, and the laser of light source 1 is divided into two bundles by fiber coupling device 2, has respectively entered reference arm and sample
Arm, enters the laser of reference arm by plane mirror M back in fiber coupling device 2, laser enter sample arm it
Afterwards, 2-D vibration mirror system 9 is scanned eyeball and returns to the result of scanning in fiber coupling device 2, by reference arm
The light returned with sample arm is interfered in fiber coupling device 2, and individual reflection can be enhanced by interference, weakens scattering light
The radiation of line, enhances the sample tissue information of different depth, and interference light carries out frequency domain Fourier transformation then into spectrometer
Computer is transmitted to by high speed linear array CCD camera later, is finally obtained by the processing of computer comprising eyeball structure information
3-D image.
As shown in Figures 3 and 4, it when posterior segment is imaged using sample arm, needs to move down the lens L7 of sample arm,
And eyepiece 8 is put on the downside of lens L7, while cutting through microscope group, using lens L2 and plane mirror M apart from biggish lens
Group moves back optical path focus point, realizes the scanning to posterior segment.
As it can be seen in figures 5 and 6, moving up lens L7 when anterior chamber of eye is imaged using sample arm, then eyepiece L8 is removed and is
System, while switching lens group, using lens L2 and plane mirror M apart from lesser lens group, optical path focus point is made to move forward, it is real
Now to the scanning of anterior chamber of eye.
Basic principles, main features, and advantages of the present invention has been shown and described above.Current row
The technical staff of industry is described in above embodiments and description it should be appreciated that the present utility model is not limited to the above embodiments
Only the principles of the present invention, the utility model also has respectively on the premise of not departing from the spirit and scope of the utility model
Kind changes and improvements, these changes and improvements are both fallen in the range of claimed invention.The requires of the utility model
Protection scope defined by appended claims and its equivalent.
Claims (8)
1. a kind of ophthalmology high speed, high resolution multifunctional optical coherence tomography device based on slit-lamp platform, including setting
OCT image optical path on slit-lamp platform and the computer for receiving OCT image optical path signal, the OCT image optical path
Sample arm including light source, to scan eyeball and the reference arm with sample arm generation interference light, the sample arm and reference arm
The light that light source issues is received, the reference arm includes lens group, and the lens group includes the first lens and positioned at the separate of lens
The plane mirror of light inlet side, which is characterized in that the lens group of the reference arm is able to carry out switching, switching it is different
First lens of lens group are different with the relative position of plane mirror.
2. a kind of ophthalmology high speed, high resolution multifunctional optical based on slit-lamp platform according to claim 1 is relevant disconnected
Layer imaging device, which is characterized in that the slit for adjusting light-inletting quantity is additionally provided at the light inlet of the reference arm.
3. a kind of ophthalmology high speed, high resolution multifunctional optical based on slit-lamp platform according to claim 2 is relevant disconnected
Layer imaging device, which is characterized in that the sample arm includes shaking to scan the 2-D vibration mirror system of eyeball and setting in two dimension
Between mirror system and eyeball and the second lens moving up and down.
4. a kind of ophthalmology high speed, high resolution multifunctional optical based on slit-lamp platform according to claim 3 is relevant disconnected
Layer imaging device, which is characterized in that the sample arm further includes being arranged between the second lens and eyeball and dismountable eyepiece.
5. a kind of ophthalmology high speed, high resolution multifunctional optical based on slit-lamp platform according to claim 1 is relevant disconnected
Layer imaging device, which is characterized in that the sample arm further includes the fixation system of aid imaging, the fixation system include to
To the target display screen that eyeball is fixed, the target display screen is connect with Computer signal.
6. a kind of ophthalmology high speed, high resolution multifunctional optical based on slit-lamp platform according to claim 5 is relevant disconnected
Layer imaging device, which is characterized in that the fixation system further includes the auxiliary positioning camera connecting with Computer signal, described auxiliary
It helps positioning camera that can acquire by sample outside hole to be shot.
7. a kind of ophthalmology high speed, high resolution multifunctional optical based on slit-lamp platform according to claim 1 is relevant disconnected
Layer imaging device, which is characterized in that further include the spectrometer handled the interference light that sample arm and reference arm generate.
8. a kind of ophthalmology high speed, high resolution multifunctional optical based on slit-lamp platform according to claim 7 is relevant disconnected
Layer imaging device, which is characterized in that further include the high speed linear array CCD camera being connected between spectrometer and computer.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201720880110.0U CN208693250U (en) | 2017-07-20 | 2017-07-20 | A kind of ophthalmology high speed, high resolution multifunctional optical coherence tomography device based on slit-lamp platform |
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| CN201720880110.0U CN208693250U (en) | 2017-07-20 | 2017-07-20 | A kind of ophthalmology high speed, high resolution multifunctional optical coherence tomography device based on slit-lamp platform |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108272432A (en) * | 2017-07-20 | 2018-07-13 | 中山大学中山眼科中心 | A kind of ophthalmology high speed, high resolution multifunctional optical coherence tomography device based on slit-lamp platform |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108272432A (en) * | 2017-07-20 | 2018-07-13 | 中山大学中山眼科中心 | A kind of ophthalmology high speed, high resolution multifunctional optical coherence tomography device based on slit-lamp platform |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20210827 Address after: 510000 No. 7, Jinsui Road, Tianhe District, Guangzhou City, Guangdong Province Patentee after: ZHONGSHAN OPHTHALMIC CENTER, SUN YAT-SEN University Patentee after: SUN YAT-SEN University Address before: 510000 1603, building 3, Zhongshan ophthalmology center, Sun Yat sen University, No. 54, Xianlie South Road, Yuexiu District, Guangzhou, Guangdong Province Patentee before: ZHONGSHAN OPHTHALMIC CENTER, SUN YAT-SEN University |
|
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20230427 Address after: Room 406, No. 1, Yichuang Street, Huangpu District (Zhongxin Guangzhou Knowledge City), Guangzhou City, Guangdong Province, 510000 Patentee after: Meishi Optical Technology (Guangdong) Co.,Ltd. Address before: 510000 No. 7, Jinsui Road, Tianhe District, Guangzhou City, Guangdong Province Patentee before: ZHONGSHAN OPHTHALMIC CENTER, SUN YAT-SEN University Patentee before: SUN YAT-SEN University |