CN208677645U - The mold of versatility haemodynamics optimization 3 D stereo sticking patch in congenital heart disease operation - Google Patents
The mold of versatility haemodynamics optimization 3 D stereo sticking patch in congenital heart disease operation Download PDFInfo
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- CN208677645U CN208677645U CN201721160120.3U CN201721160120U CN208677645U CN 208677645 U CN208677645 U CN 208677645U CN 201721160120 U CN201721160120 U CN 201721160120U CN 208677645 U CN208677645 U CN 208677645U
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Abstract
The utility model relates to a kind of molds of the 3 D stereo sticking patch of versatility haemodynamics optimization for preparing treatment congenital heart disease, it is made of upper mold and lower mold, upper mold pedestal and lower mold base are cuboid, the lower surface of upper mold pedestal is equipped with upper mold edge protuberance, the lower surface of upper mold pedestal is recessed to form mould curved surface, upper mold pedestal is equipped with 1 channel for leading to mould curved surface from top to bottom and 1 leads to the channel near mould curved surface from top to bottom, 4 angles of upper mold pedestal are respectively provided with 1 top-down channel, the upper surface of lower mold base is equipped with lower mold edge groove, the upper surface of lower mold base forms mold convex surface.Its advantage is shown: be different from two-dimentional sticking patch used at present, the pericardium sticking patch of the mold preparation of the utility model be 3 D stereo, it is general, be fitted haemodynamics.
Description
Technical field
The utility model relates to the field of medical instrument technology, specifically, being versatility blood in congenital heart disease operation
The mold of hydromechanics optimization 3 D stereo sticking patch.
Background technique
Congenital heart disease and sticking patch application: newest medical information shows congenital heart disease (hereinafter referred to as " the first heart in recent years
Disease ") it is common disease, frequently-occurring disease in infant.In China, congenital heart disease disease incidence accounts for about 8 ‰~the 12 ‰ of born baby, has become
For the primary cause of disease of neonatal death.According to statistics, there are about 150,000 or so newly-increased congenital heart disease patients every year in China, wherein complicated first
Cardiaopath accounts for about 30~40%.With the progress of medical science and technology, many infants, non-neonate congenital heart disease include complexity
Heart malformations can have been eradicated at present, and domestic there are about 3~40,000 infants to receive congenital heart disease operative treatment every year.Wherein, portion
Point arteries of complex congenital heart defect hypotype is due to blood vessel and efferent tract is narrow or obstruction etc., and Vein graft sticking patch is needed to expand narrow blood vessel
Or efferent tract carries out surgical intervention.In previous clinical position, vascular patch implantation position, shape, size and angle
Selection mainly judges and determines according to operator clinical experience.Due to lacking objective, accurate judgment method, postoperative possibility
Sticking patch distortion, deformation, angulation can occur, lead to the remaining generation blocked.And these can be by computer aided animation most
The versatility vascular patch of excellent haemodynamics designs and 3D printing mold processes pericardium sticking patch forming technique to solve.I.e.
According to large-scale investigation, using the cardiovascular development form of most of asian population as template, haemodynamics meter is carried out
The simulation of calculation machine determines the haemodynamics optimization design scheme of the versatility vascular patch of suitable most of patients vascular morphology, with
And versatility 3D printing mold is carried out according to this scheme, it is final to realize pericardium sticking patch forming technique.
Calculate haemodynamics: in recent years, with the continuous development of computer technology, based on numerical simulation, in conjunction with
The calculating haemodynamics (Computational Hemodynamics) that flowing three-dimensional visualization technique grows up is quantitative
Hemodynamic parameter variation is analyzed, in vitro study blood flow movement track and objective quantitative assessment, design sticking patch scheme provide
It may.It calculates haemodynamics and utilizes clinical medicine image data, such as ultrasound (Ultrasound, US), nuclear magnetic resonance
(Magnetic Resonance, MRI), Electronic Computer Tomography (Computed Tomography, CT) image,
By carrying out precise measurement to many-sided information such as blood vessel morphology, haemodynamics, heart function, according to patient itself dissection and
Physilogical characteristics, by solving the blood flow governing equation that the physiologic information (such as fluctuation pressure, blood flow) for assigning and suffering from is boundary condition
Carry out the blood flow situation of the true vivo environment of analog approximation, and then patient's sticking patch implantation front and back outflow tract of right ventricle blood flow can be assessed
The change of kinetic characteristics is more intuitively studied the selection of the implantation position, shape, size and angle of sticking patch for doctor, and is mended
Influence of the factors such as sheet material characteristic to haemodynamics provides important means.
Summary of the invention
The purpose of this utility model is to provide a kind of versatility haemodynamics optimization for preparing treatment congenital heart disease
3 D stereo sticking patch mold.
To achieve the above object, the technical scheme adopted by the utility model is that:
A kind of mold of the 3 D stereo sticking patch for the versatility haemodynamics optimization preparing treatment congenital heart disease, institute
The mold of the 3 D stereo sticking patch of the versatility haemodynamics optimization for the preparation treatment congenital heart disease stated by upper mold and
Lower mold composition, upper mold pedestal and lower mold base are cuboid, and it is convex that the lower surface of upper mold pedestal is equipped with upper mold edge
It rises, the lower surface of upper mold pedestal is recessed to form mould curved surface, and upper mold pedestal is equipped with 1 and leads to mould curved surface from top to bottom
Channel and 1 lead to the channel near mould curved surface from top to bottom, 4 angles of upper mold pedestal be respectively provided with 1 it is top-down
Channel, the upper surface of lower mold base are equipped with lower mold edge groove, and the upper surface of lower mold base forms mold convex surface.
Mould curved surface is matched with the upper surface for the 3 D stereo sticking patch that versatility haemodynamics optimizes, mold convex surface and logical
With the lower surface matching for the 3 D stereo sticking patch that property haemodynamics optimizes, the 3 D stereo of versatility haemodynamics optimization is mended
The shape of piece be head end is small, tail end is big, curved surface from head end to curving.
The utility model advantage is:
1, different from the mold of two-dimentional sticking patch used at present, the pericardium sticking patch of the mold preparation of the utility model is three-dimensional
Three-dimensional.
2, the pericardium sticking patch of the mold preparation of the utility model is general, and majority of populations is suitble to use.
3, the pericardium sticking patch of the mold preparation of the utility model has been fitted haemodynamics.
Detailed description of the invention
Attached drawing 1 is a kind of solid of the mold of the 3 D stereo sticking patch of versatility haemodynamics optimization of the utility model
Schematic diagram.
Attached drawing 2 is a kind of the vertical of the upper mold of the 3 D stereo sticking patch of versatility haemodynamics optimization of the utility model
Body schematic diagram.
Attached drawing 3 is a kind of facing upward for the upper mold of the 3 D stereo sticking patch of versatility haemodynamics optimization of the utility model
View.
Attached drawing 4 is a kind of the vertical of the lower mold of the 3 D stereo sticking patch of versatility haemodynamics optimization of the utility model
Body schematic diagram.
Attached drawing 5 is a kind of bowing for the lower mold of the 3 D stereo sticking patch of versatility haemodynamics optimization of the utility model
View.
Attached drawing 6 is a kind of the vertical of the upper mold of the 3 D stereo sticking patch of versatility haemodynamics optimization of the utility model
Body schematic diagram.
Attached drawing 7 is a kind of facing upward for the upper mold of the 3 D stereo sticking patch of versatility haemodynamics optimization of the utility model
View.
Attached drawing 8 is a kind of the vertical of the lower mold of the 3 D stereo sticking patch of versatility haemodynamics optimization of the utility model
Body schematic diagram.
Attached drawing 9 is a kind of bowing for the lower mold of the 3 D stereo sticking patch of versatility haemodynamics optimization of the utility model
View.
Specific embodiment
The utility model is further described below with reference to embodiment and referring to attached drawing.Appended drawing reference involved in attached drawing
It is as follows with component part:
1, upper mold
11, upper mold pedestal
12, upper mold edge protuberance
13, mould curved surface
14, channel
2, lower mold
21, lower mold base
22, lower mold edge groove
23, mold convex surface
24, channel
Embodiment 1
(1) data acquisition three-dimensional digitalization model is acquired
According to large range of investigation, the main cardiovascular development form for acquiring asian population is statistical sample.It is logical
Cross the clinical MRI image data and supersonic blood metrical information for obtaining patient.A series of two dimensions are obtained by MRI scan
DICOM image data is to the subsequent three-dimensional reconstruction for carrying out anatomical structure.It is obtained in each lumen at any time by cardiac ultrasonic scanning
Between the blood flowing speed information that changes.The image data of DICOM format is imported to highly integrated Medical Image Processing software
Materialise- In, the image data generated by MRI scan is pre-processed, sticking patch is chosen by screening
The intact image of implanted region rebuilds 3-dimensional digital pulmonary artery image.
(2) analysis individuation virtual operation determine sticking patch design using large sample size patient medical image data into
Line number according to statistics, and combines patient anatomical's feature to design and the versatility sticking patch of Most patients is suitble to be implanted into scheme, as unified
Implantation position, shape, size and angle.Implement virtual sticking patch using cad technique to be implanted into, carry out haemodynamics be quantitatively evaluated with
Visualization display completes the analysis of calculated result, is optimized according to its haemodynamics feature.Utilize computational fluid dynamics
Method establishes blood flow movement computation model after the implantation of accurate simulation vascular patch, to three-dimensional reconstruction sticking patch implanted region blood vessel mould
Type carries out haemodynamics simulation and analysis.With the Computational Fluid Dynamic Analysis software based on finite volume scheme then
Ansys-Fluent 14.0 carries out Simulation of Blood.It is calculated by computer C Programming with Pascal Language User-Defined Functions (UDF)
Control realizes that pulsatile blood flow three-dimensional flow field considers respiration, vascular resistence, the hemodynamic under the physiological conditions such as blood vessel elasticity
Learn accurate simulation, and by calculated result carry out visualization processing compared with, to versatility sticking patch implantation position, shape, size and
Situations such as angle, carries out overall merit, determines that the sticking patch form of the most suitable best haemodynamics of Most patients and operation are implemented
Scheme.
(3) sticking patch molding die is made using 3D printing technique, explores individual's sticking patch fixing means combination 3D and beats
Print technology, production designs the versatility sticking patch design scheme molding die for being most suitable for Most patients through virtual operation, with clinic
Surgical doctor inquires into surgical procedure feasibility and operating feature jointly, in conjunction with Hemodynamic analysis as a result, being determined for compliance with mostly
The optimal operation of number blood stream of patients's dynamic conditions is implanted into scheme.Has the fixation side using glutaraldehyde to sticking patch based on clinic
Method prints sticking patch molding die in conjunction with 3D, explores the versatility sticking patch that Digital Design meets Most patients blood vessel physiological property
Forming technique is carried out follow-up and postoperative clinical data acquisition, is predicted the issuable complication of postoperative patient, for correlation
Medical personnel provides reference.
Embodiment 2
The children with CHD that an example needs to carry out sticking patch transplanting is chosen, needs to expand using Vein graft sticking patch in surgical procedure
Narrow outflow tract of right ventricle and pulmonary artery (including branch) achieve the purpose that surgical radical treatment to release outflow obstruction.
The preoperative image data of infant is acquired, calculating Hemodynamic analysis is carried out by MRI and the acquisition of cardiac ultrasonic method
The model construction base that the data such as blood flow velocity are simulated as evaluation in required 3 D anatomy structure information and Diverging area
Plinth and boundary condition basis of design complete the three-dimensional reconstruction of infant individuation sticking patch implanted region anatomical structure, pass through infant
The simulation of body haemodynamics and virtual operation are determined for compliance with the sticking patch design of the best haemodynamics of this infant.It is beaten using 3D
Print technology, production infant individuation sticking patch form physics tangible mold, strict sterilization, to fix for Vein graft sticking patch in art
Molding.
Take infant Vein graft in operation, be placed on individuation sticking patch mold convex surface, then with mould curved surface part into
Row fastens, and the fixed glutaraldehyde solution used of pericardium sticking patch is perfused into it, is horizontally arranged molding to be fixed.It is removed after 15 minutes
Mold obtains molded pericardium sticking patch, and shape and angle are ideal, are dramatically fitted Individual Digital and design sticking patch mould
Type can help well patient easily to position implant site, shape and angle during surgery.Importantly, this symbol
The body vessel repairing and graft application for closing haemodynamics individuation 3 D stereo sticking patch, can preferably help patient to carry out
Post-operative recovery reduces complication.
This research utilizes computational fluid dynamics on the basis of vascular patch clinical treatment forms, fixes previous method
And 3D printing technique makes the versatility sticking patch molding die for being suitble to Most patients, realizes patient's treatment easily and effectively and full
Sufficient haemodynamics design, so that surgical procedure has something to base on, is conducive to the improvement of modus operandi and the foundation of clinical criteria.This
Outside, sticking patch molding, technique for fixing are easily operated in this research, are conducive to clinical expansion and popularize.
Embodiment 3
Attached drawing 1-5 is please referred to, attached drawing 1 is the stereoscopic schematic diagram of mold, and attached drawing 2 is the stereoscopic schematic diagram of upper mold, attached drawing 3
It is the bottom view of upper mold, attached drawing 4 is the stereoscopic schematic diagram of lower mold, and attached drawing 5 is the top view of lower mold.
The mold of the 3 D stereo sticking patch of the versatility haemodynamics optimization is by upper mold (1) and lower mold (2)
Composition.Upper mold (1) is by upper mold pedestal (11), upper mold edge protuberance (12), mould curved surface (13) and channel (14) group
At.Lower mold (2) is made of lower mold base (21), lower mold edge groove (22) and mold convex surface (23).
Upper mold pedestal (11) is cuboid.The lower surface of upper mold pedestal (11) is equipped with upper mold edge protuberance (12),
There is a certain distance at the edge of upper mold edge protuberance (12) and upper mold pedestal (11).The lower surface of upper mold pedestal (11) is recessed
It falls into and is formed mould curved surface (13), the upper surface of mould curved surface (13) and the 3 D stereo sticking patch by haemodynamics optimization
Match.Four angles of the inside of the upper mold edge protuberance (12) of upper mold pedestal (11) form 4 top-down channels (14),
Upper mold pedestal (11) forms 1 top-down channel (14) for leading to mould curved surface (13), upper mold pedestal (11) also shape
Top-down lead to the channel (14) of mould curved surface (13) nearby at 1.
Lower mold base (21) is cuboid.The upper surface of lower mold base (11) is equipped with lower mold edge groove (22),
Lower mold edge groove (22) matches with upper mold edge protuberance (12).It is convex that the upper surface of lower mold base (21) is equipped with mold
Face (23), mold convex surface (23) are matched with the lower surface of the 3 D stereo sticking patch by haemodynamics optimization.By blood flow
The 3 D stereo sticking patch of mechanics optimization is designed by the method for embodiment 1.
The shape of 3 D stereo sticking patch by haemodynamics optimization is curved surface, and head end is small, tail end is big, and head end is to side
Bending.Upper mold (1) and lower mold (2) can be made by 3D printing.
Embodiment 4
Attached drawing 4-7 is please referred to, attached drawing 4 is the perspective view of lower mold, and attached drawing 5 is the top view of lower mold, and attached drawing 6 is upper mold
The perspective view of tool, attached drawing 7 are the bottom views of upper mold.
Compared with Example 3, the upper mold (1) of the present embodiment is not provided with channel (14).
The mold of the 3 D stereo sticking patch of the versatility haemodynamics optimization is by upper mold (1) and lower mold (2)
Composition.Upper mold (1) is made of upper mold pedestal (11), upper mold edge protuberance (12) and mould curved surface (13).Lower mold
(2) it is made of lower mold base (21), lower mold edge groove (22) and mold convex surface (23).
Upper mold pedestal (11) is cuboid.The lower surface of upper mold pedestal (11) is equipped with upper mold edge protuberance (12),
There is a certain distance at the edge of upper mold edge protuberance (12) and upper mold pedestal (11).The lower surface of upper mold pedestal (11) is recessed
It falls into and is formed mould curved surface (13), the upper surface of mould curved surface (13) and the 3 D stereo sticking patch by haemodynamics optimization
Match.
Lower mold base (21) is cuboid.The upper surface of lower mold base (11) is equipped with lower mold edge groove (22),
Lower mold edge groove (22) matches with upper mold edge protuberance (12).It is convex that the upper surface of lower mold base (21) is equipped with mold
Face (23), mold convex surface (23) are matched with the lower surface of the 3 D stereo sticking patch by haemodynamics optimization.
3 D stereo sticking patch by haemodynamics optimization is designed by the method for embodiment 1.By haemodynamics
The shape of the 3 D stereo sticking patch of optimization is curved surface, and head end is small, tail end is big, and head end is to curving.
Upper mold (1) and lower mold (2) can be made by 3D printing.
Embodiment 5
Attached drawing 6-9 is please referred to, attached drawing 6 is the perspective view of upper mold, and attached drawing 7 is the bottom view of upper mold, and attached drawing 8 is lower die
The perspective view of tool, attached drawing 9 are the top views of lower mold.
Compared with Example 3, the upper mold (1) of the present embodiment is not provided with channel (14), and lower mold (2) is equipped with channel
(24)。
The mold of the 3 D stereo sticking patch of the versatility haemodynamics optimization is by upper mold (1) and lower mold (2)
Composition.Upper mold (1) is made of upper mold pedestal (11), upper mold edge protuberance (12) and mould curved surface (13).Lower mold
(2) it is made of lower mold base (21), lower mold edge groove (22), mold convex surface (23) and channel (24).
Upper mold pedestal (11) is cuboid.The lower surface of upper mold pedestal (11) is equipped with upper mold edge protuberance (12),
There is a certain distance at the edge of upper mold edge protuberance (12) and upper mold pedestal (11).The lower surface of upper mold pedestal (11) is recessed
It falls into and is formed mould curved surface (13), the upper surface of mould curved surface (13) and the 3 D stereo sticking patch by haemodynamics optimization
Match.
Lower mold base (21) is cuboid.The upper surface of lower mold base (11) is equipped with lower mold edge groove (22),
Lower mold edge groove (22) matches with upper mold edge protuberance (12).It is convex that the upper surface of lower mold base (21) is equipped with mold
Face (23), mold convex surface (23) are matched with the lower surface of the 3 D stereo sticking patch by haemodynamics optimization.Lower mold base
(21) four angles of the inside of lower mold edge groove (22) form 4 channels (24) from bottom to top, lower mold base
(11) 1 channel (24) for leading to mold convex surface (23) from bottom to top is formed.
3 D stereo sticking patch by haemodynamics optimization is designed by the method for embodiment 1.By haemodynamics
The shape of the 3 D stereo sticking patch of optimization is curved surface, and head end is small, tail end is big, and head end is to curving.Upper mold (1) and lower mold
(2) it can be made by 3D printing.
The above is only the preferred embodiment of the utility model, it is noted that for the common skill of the art
Art personnel can also make several improvement and supplement without departing from the principle of this utility model, these are improved and supplement
Also it should be regarded as the protection scope of the utility model.
Claims (2)
1. a kind of mold of the 3 D stereo sticking patch for the versatility haemodynamics optimization for preparing treatment congenital heart disease, special
Sign is, the mold of the 3 D stereo sticking patch of the versatility haemodynamics optimization of the preparation treatment congenital heart disease by
Upper mold and lower mold composition, upper mold pedestal and lower mold base are cuboid, and the lower surface of upper mold pedestal is equipped with upper mold
Has edge protuberance, the lower surface of upper mold pedestal is recessed to form mould curved surface, and upper mold pedestal is equipped with 1 and leads to mould from top to bottom
Have the channel of concave surface and 1 leads to the channel near mould curved surface from top to bottom, 4 angles of upper mold pedestal are respectively provided with 1 certainly
Channel under above, the upper surface of lower mold base are equipped with lower mold edge groove, and the upper surface of lower mold base forms mold
Convex surface.
2. the 3 D stereo of the versatility haemodynamics optimization of preparation treatment congenital heart disease according to claim 1
The mold of sticking patch, which is characterized in that the upper surface of mould curved surface and the 3 D stereo sticking patch of versatility haemodynamics optimization
Match, mold convex surface is matched with the lower surface for the 3 D stereo sticking patch that versatility haemodynamics optimizes, versatility haemodynamics
The shape of the 3 D stereo sticking patch of optimization be head end is small, tail end is big, curved surface from head end to curving.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201721160120.3U CN208677645U (en) | 2017-09-12 | 2017-09-12 | The mold of versatility haemodynamics optimization 3 D stereo sticking patch in congenital heart disease operation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201721160120.3U CN208677645U (en) | 2017-09-12 | 2017-09-12 | The mold of versatility haemodynamics optimization 3 D stereo sticking patch in congenital heart disease operation |
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| CN208677645U true CN208677645U (en) | 2019-04-02 |
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| CN201721160120.3U Active CN208677645U (en) | 2017-09-12 | 2017-09-12 | The mold of versatility haemodynamics optimization 3 D stereo sticking patch in congenital heart disease operation |
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