CN208649340U - A kind of efficiently still air-breather - Google Patents
A kind of efficiently still air-breather Download PDFInfo
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- CN208649340U CN208649340U CN201820824956.7U CN201820824956U CN208649340U CN 208649340 U CN208649340 U CN 208649340U CN 201820824956 U CN201820824956 U CN 201820824956U CN 208649340 U CN208649340 U CN 208649340U
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- defoaming
- film
- still air
- breather
- gas
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Abstract
The gas-liquid of a kind of efficiently still air-breather, defoaming position, the sealing position at middle part, lower end including upper end exchanges position；The sealing position setting is below defoaming position, gas-liquid exchanges position and is arranged below sealing position, it defoams position and places position and foam overflow position including defoaming film sealing position, defoaming film, the defoaming film sealing position setting is defoaming above film placement position, and the foam overflow position is arranged places in position in defoaming film；Gas-liquid exchange position includes microscreen, snorkel and microvesicle ventilation head, and the snorkel runs through whole device, and microvesicle ventilation head is mounted on snorkel bottom end, and microscreen is arranged in device lower end two sides；The utility model increases the dissolved oxygen transmission efficiency inside isolated still air-breather, while leading to the problem of a large amount of bubbles because ventilatory capacity is larger when can solve High Density Cultivation again.
Description
Technical field
The utility model relates to cell biologies and biological product technical field, and in particular to a kind of efficiently still ventilation dress
It sets.
Background technique
Still ventilating technology relatively typically utilizes the principle that can permeate gas when silicone tube thin-walled under lower pressure,
Since infiltration extremely tiny flow quantity is lower, so gas-liquid exchange can occur sufficiently to avoid the generation of bubble.Also exactly because
For the lower reason of flow, required exchange area is also quite huge when volume of culture is larger, so big
Rarely has such technical application of discovery 200L or more in scale cell culture.Such as application No. is the China of CN200820200454.3
Patent, a kind of bioreactor use insulating space to lead directly to gas, although without the practical bubble eliminated when gas-liquid exchanges,
But it is that of avoiding the contact of bubble with culture cell, has equally reached the still ventilatory effect on practical significance.But just because of
The reason of isolation, causes delivered spaced more to which dissolved oxygen transmission efficiency reduces, relatively difficult when High Density Cultivation.
Utility model content
In view of the deficiencies of the prior art, lacking the purpose of this utility model is to overcome isolated still ventilating technology
Point increases the dissolved oxygen transmission efficiency inside isolated still air-breather, while because of ventilation when can solve High Density Cultivation again
It measures and larger leads to the problem of a large amount of foams.
To achieve the above objectives, the present invention adopts the following technical solutions:
The gas-liquid of a kind of efficiently still air-breather, defoaming position, the sealing position at middle part, lower end including upper end exchanges position；
Below defoaming position, gas-liquid exchanges position and is arranged below sealing position for sealing position setting, defoaming position include defoaming film sealing position,
It defoams film and places position and foam overflow position, the defoaming film sealing position setting is placed above position in defoaming film, the foam overflow
Position setting is placed in position in defoaming film；Gas-liquid exchange position includes that microscreen, snorkel and microvesicle ventilation head, the snorkel pass through
Whole device is worn, microvesicle ventilation head is mounted on snorkel bottom end, and microscreen is arranged in device lower end two sides.
Preferably, the defoaming film is micro-strainer of the diameter between 5-100um.
Preferably, the number of plies of the defoaming film is between 2-10 layers.
Preferably, the material of the defoaming film includes but is not limited to stainless steel or silk.
Preferably, the sealing position accounts for the 10%-80% of whole device length.
Preferably, the microvesicle ventilation head bore diameter is between 1-50um.
Preferably, the microscreen aperture is between 5-100um.
The utility model has the beneficial effects that:
The gas-liquid exchange position of lower end is because microvesicle ventilation provides higher gas-liquid exchange efficiency, while improving outside device
The presence of side negative pressure, increased foam accumulation, is defoamed by the defoaming position of upper end, and foam can after multilayer defoaming film
To reach defoaming effect, the sealing position at middle part is prevented on the outside of foam overflow device for fusion and explosion step by step.
Detailed description of the invention
Fig. 1 is the overall structure diagram of the efficiently still air-breather of the utility model.
Appended drawing reference: 1, film sealing position is defoamed；2, defoaming film places position；3, sealing position；4, microscreen；5, foam overflow
Position；6, snorkel；7, microvesicle ventilation head.
Specific embodiment
In the following, being described further in conjunction with attached drawing and specific embodiment to the utility model:
As shown in Figure 1, a kind of efficiently still air-breather, defoaming position, the sealing position 3 at middle part, lower end including upper end
Gas-liquid exchanges position；Below defoaming position, gas-liquid exchanges position and is arranged below sealing position 3 for the setting of sealing position 3, and defoaming position includes
Film sealing position 1, defoaming film placement position 2 and foam overflow position 5 are defoamed, the setting of defoaming film sealing position 1 places position 2 in defoaming film
Top, the setting of foam overflow position 5 are placed in position 2 in defoaming film；Gas-liquid exchange position includes microscreen 4, snorkel 6 and micro-
Bubble ventilation head 7, the snorkel 6 run through whole device, and microvesicle ventilation head 7 is mounted on 6 bottom end of snorkel, and microscreen 4 is arranged
In device lower end two sides.
Defoaming film is micro-strainer of the diameter in 10um, and the number of plies is 8 layers, and material is stainless steel.
Sealing position 3 accounts for the 65% of whole device length.
Microvesicle ventilates 7 aperture of head as 5um, and 4 aperture of microscreen is 10um.
When being passed through gas from snorkel 6, enter inside still air-breather by microvesicle ventilation sintering head, then
Foam floats, and can not be discharged by middle part sealing position 3, is overflowed by foam overflow position 5 and reaches defoaming film, defoams film sealing position 1
Foam is forced to place the defoaming film of position 2 by reaching defoaming purpose from defoaming film.
The gas-liquid exchange position of lower end is because microvesicle ventilation provides higher gas-liquid exchange efficiency, while improving outside device
The presence of side negative pressure, however foam accumulation is increased, it can only be defoamed by the defoaming position of upper end.Practical discovery foam is through excessive
It can be merged step by step after layer defoaming film and explosion is to reach defoaming effect.
Film position is defoamed when if microvesicle floating in practical application within the scope of training volume liquid level, foam can slowly glue
It is attached to liquid level and is slowly spilled over on the outside of device, defoaming effect is not achieved, so the sealing position 3 at setting middle part is necessary.
It will be apparent to those skilled in the art that can make various other according to the above description of the technical scheme and ideas
Corresponding change and deformation, and all these changes and deformation all should belong to the protection of the utility model claims
Within the scope of.
Claims (7)
1. a kind of efficiently still air-breather, which is characterized in that the gas of defoaming position, the sealing position at middle part, lower end including upper end
Liquid exchanges position；Below defoaming position, gas-liquid exchanges position and is arranged below sealing position for the sealing position setting, and defoaming position includes defoaming
Film sealing position, defoaming film place position and foam overflow position, and the defoaming film sealing position setting is placed above position in defoaming film, described
The setting of foam overflow position is placed in position in defoaming film；Gas-liquid exchange position include microscreen, snorkel and microvesicle ventilation head, it is described
Snorkel runs through whole device, and microvesicle ventilation head is mounted on snorkel bottom end, and microscreen is arranged in device lower end two sides.
2. efficiently still air-breather according to claim 1, which is characterized in that the defoaming film is diameter in 5-
Micro-strainer between 100um.
3. efficiently still air-breather according to claim 2, which is characterized in that the number of plies of the defoaming film is at 2-10 layers
Between.
4. efficiently still air-breather according to claim 3, which is characterized in that the material of the defoaming film is stainless steel
Or silk.
5. efficiently still air-breather according to claim 1, which is characterized in that the sealing position accounts for whole device length
10%-80%.
6. efficiently still air-breather according to claim 1, which is characterized in that the microvesicle ventilation head bore diameter is in 1-
Between 50um.
7. according to efficiently still air-breather according to claim 1, which is characterized in that the microscreen aperture is in 5-
Between 100um.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820824956.7U CN208649340U (en) | 2018-05-30 | 2018-05-30 | A kind of efficiently still air-breather |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820824956.7U CN208649340U (en) | 2018-05-30 | 2018-05-30 | A kind of efficiently still air-breather |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN208649340U true CN208649340U (en) | 2019-03-26 |
Family
ID=65779359
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201820824956.7U Active CN208649340U (en) | 2018-05-30 | 2018-05-30 | A kind of efficiently still air-breather |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN208649340U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114561291A (en) * | 2022-03-21 | 2022-05-31 | 广州齐志生物工程设备有限公司 | 500ml small-sized one-control multi-cell bioreactor |
-
2018
- 2018-05-30 CN CN201820824956.7U patent/CN208649340U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114561291A (en) * | 2022-03-21 | 2022-05-31 | 广州齐志生物工程设备有限公司 | 500ml small-sized one-control multi-cell bioreactor |
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