CN208611373U - A kind of storage unit of the Nano medication convenient for operation - Google Patents
A kind of storage unit of the Nano medication convenient for operation Download PDFInfo
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- CN208611373U CN208611373U CN201721512788.XU CN201721512788U CN208611373U CN 208611373 U CN208611373 U CN 208611373U CN 201721512788 U CN201721512788 U CN 201721512788U CN 208611373 U CN208611373 U CN 208611373U
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- drug
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- sphere
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Abstract
The utility model relates to a kind of storage units of Nano medication convenient for operation, including the nanogel being made of multiple spheres and multiple connecting rods, the sphere is alternatively arranged with connecting rod, and the sphere and connecting rod are in same axis, is embedded with drug in the nanogel.The contact area of drug and implant is increased, it is ensured that the speed of drug release continues efficiently on the one hand by setting sphere structure using the whole carrier in the nanogel of candied haws on a stick structure as drug;On the other hand, the structure of connecting rod is convenient for the clamping of tweezers, can also cooperate the suture of operation, and fixation is attached at aura position, consequently facilitating the development of operation.
Description
Technical field
The utility model relates to the slow release method of drug more particularly to a kind of storage lists of the Nano medication convenient for operation
Member.
Background technique
To reach optimal prevention or therapeutic effect, need to give drug or bioactive substance to many diseases or state
And reach stable or lasting levels of drugs in vivo.To achieve the above object, prior art means using multiple dose administration or
Person is realized using the system of sustainable drug release or controllable drug release.Wherein, more meterings are also known as repeat administration and refer to by certain
The medication that administration reaches blood concentration and is maintained in therapeutic window is repeated several times in dosage, certain intervals time.Clinically
Often through multiple dose administration to maintain blood concentration in therapeutic window.Principle is that injection or medication are calculated according to blood concentration
Amount, the single drug duration is short, needs repeatedly to be administered patient.And controlled release pharmaceutical compositions have two big main advantages,
First is that higher treatment level can be maintained in longer time, second is that can subtract while reaching with quick releasing formulation same effect
Few medicining times, to improve the compliance of patient.Slow release method is efficiently used, drug is implanted directly into lesions position, when long
Between be sustained drug effect, can not only mitigate the pain of patient, also can the release of more scientific and reasonable control drug effect.Wherein, hydrogel conduct
Pharmaceutical carrier plays an important role in terms of medicine controlled releasing.The response performance of hydrogel be by the reversible volumetric phase transformation of gel come
Realize, and make it sensor, artificial muscle, drug controlled release, organizational project, catalyst system, enzyme in terms of
It has broad application prospects.
Currently, European and American developed countries have started the clinical application of similar technique many years ago.Such as chip implanted prosthetics, drug
It is big to be sustained side effect, silica gel stick technology is there are nondegradable defect, and patient must face the pain of second operation, and small plant
Enter in body technique, since release amount of medicine is uncontrollable, there is also huge side effects.And it is newest research shows that nanometer
Gel, which can be loaded, to be sent to inside cell and passes through biomembrane.This nanogel has good stability and can protect
Shield bioactie agent is not degraded by endocellular metabolism system.Nanogel conveys and improves oral and brain in systemic medication
Very big potential is shown in terms of the bioavilability of position.
For embedding in ophthalmologic operation rear vitreous body, muscle embedding etc. needs to use hydrogel to control the release of drug.
There are slower and slower drawbacks for the drug releasing rate of traditional drug controlled release system, and then influence using effect.And nanometer is multiple
Closing gel has excellent mechanical performance, high-biocompatibility and injectable type, has on drug release and soft tissue repair potential
Purposes.
Utility model content
In view of the above-mentioned state of the art, the technical problem to be solved by the utility model is to provide a kind of stabilizations to hold
The storage unit of continuous release drug and the Nano medication convenient for operation convenient for operation.
Technical solution adopted by the utility model to solve the above technical problems is as follows: a kind of Nano medication convenient for operation
Storage unit, including the nanogel being made of multiple spheres and multiple connecting rods, the sphere is alternatively arranged with connecting rod, the ball
Body and connecting rod are in same axis, are embedded with drug in the nanogel.
Further, the diameter of the sphere is 3mm.
Further, the length of the connecting rod is 1mm.
Further, the entire length of the nanogel is 20-30mm.
It is the utility model compared with prior art that the utility model, which solves technical solution used by above-mentioned technical problem,
Beneficial effect be: using the whole carrier in the nanogel of candied haws on a stick structure as drug, on the one hand by the way that ball is arranged
Body structure increases the contact area of drug and implant, promotes the rate of drug release;On the other hand, the structure of connecting rod is convenient for
The clamping of tweezers can also cooperate the suture of operation, and fixation is attached at aura position, consequently facilitating the development of operation.
Detailed description of the invention
Fig. 1 is novel overall structure diagram described in the utility model.
Specific embodiment
The following will be combined with the drawings in the embodiments of the present invention, to the skill embodiment in the utility model embodiment, and
The embodiment being not all of.Based on the embodiments of the present invention, those of ordinary skill in the art are not making creativeness
Every other embodiment obtained, fall within the protection scope of the utility model under the premise of labour.
As shown in Figure 1, technical solution adopted by the utility model to solve the above technical problems is as follows: a kind of convenient for operation
The storage unit of Nano medication, including the gel particle with uniform nanostructure being made of multiple spheres 1 and multiple connecting rods 2
(referred to as: nanogel), the sphere 1 is alternatively arranged with connecting rod 2, and the sphere 1 is in same axis with connecting rod 2, described
Drug is embedded in nanogel.
The diameter of the sphere 1 is 3mm.
The length of the connecting rod 2 is 1mm.
The entire length of the nanogel is 20-30mm.
Its preparation process can be laser processing or 3D printing.
It is the utility model compared with prior art that the utility model, which solves technical solution used by above-mentioned technical problem,
Beneficial effect be: using the whole carrier in the nanogel of candied haws on a stick structure as drug, on the one hand by the way that ball is arranged
Body structure increases the contact area of drug and implant, it is ensured that the speed of drug release continues efficiently;On the other hand, even
The structure of bar is convenient for the clamping of tweezers, can also cooperate the suture of operation, and fixation is attached at aura position, consequently facilitating operation is opened
Exhibition.
It is obvious to a person skilled in the art that the present invention is not limited to the details of the above exemplary embodiments, and
And without departing substantially from the spirit or essential attributes of the utility model, it can realize that this is practical new in other specific forms
Type.Therefore, in all respects, the present embodiments are to be considered as illustrative and not restrictive, this is practical new
The range of type is indicated by the appended claims rather than the foregoing description, it is intended that containing for the equivalent requirements of the claims will be fallen in
All changes in justice and range are embraced therein.It should not treat any reference in the claims as limiting
Related claim.
Claims (1)
1. a kind of storage unit of the Nano medication convenient for operation, which is characterized in that including by multiple spheres and multiple connection rod sets
At nanogel, the sphere is alternatively arranged with connecting rod, and the sphere and connecting rod are in same axis, in the nanogel
It is inside embedded with drug, the diameter of the sphere is 3mm, and the length of the connecting rod is 1mm, and the entire length of the nanogel is
20-30mm。
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201721512788.XU CN208611373U (en) | 2017-11-06 | 2017-11-06 | A kind of storage unit of the Nano medication convenient for operation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201721512788.XU CN208611373U (en) | 2017-11-06 | 2017-11-06 | A kind of storage unit of the Nano medication convenient for operation |
Publications (1)
Publication Number | Publication Date |
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CN208611373U true CN208611373U (en) | 2019-03-19 |
Family
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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CN201721512788.XU Active CN208611373U (en) | 2017-11-06 | 2017-11-06 | A kind of storage unit of the Nano medication convenient for operation |
Country Status (1)
Country | Link |
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CN (1) | CN208611373U (en) |
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2017
- 2017-11-06 CN CN201721512788.XU patent/CN208611373U/en active Active
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