CN207950204U - A kind of storage unit of injection-type Nano medication - Google Patents
A kind of storage unit of injection-type Nano medication Download PDFInfo
- Publication number
- CN207950204U CN207950204U CN201721512720.1U CN201721512720U CN207950204U CN 207950204 U CN207950204 U CN 207950204U CN 201721512720 U CN201721512720 U CN 201721512720U CN 207950204 U CN207950204 U CN 207950204U
- Authority
- CN
- China
- Prior art keywords
- nanogel
- injection
- type nano
- cylindrical structure
- storage unit
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Abstract
The utility model is related to a kind of storage units of injection-type Nano medication, include the nanogel in cylindrical structure, the length of the nanogel of the cylindrical structure is 8mm.Using the nanogel of cylindrical structure, on the one hand drug one easy to carry is logical is injected into the tissues such as integumentary musculature, on the other hand can effectively reduce immune response of the human body to implantation material.
Description
Technical field
The utility model is related to the slow release method of drug more particularly to a kind of storage units of injection-type Nano medication.
Background technology
For the prevention or therapeutic effect for reaching best, many diseases or state are needed to give drug or bioactive substance
And reach stable or lasting levels of drugs in vivo.To achieve the above object, prior art means using multiple dose administration or
Person is realized using the system of sustainable drug release or controllable drug release.Wherein, it refers to by certain that more meterings, which are also known as repeat administration,
The medication that administration makes blood concentration reach and is maintained in therapeutic window is repeated several times in dosage, certain intervals time.Clinically
Often through multiple dose administration to maintain blood concentration in therapeutic window.Principle is to calculate injection or medication according to blood concentration
Amount, the single drug duration is short, needs repeatedly to be administered patient.And controlled release pharmaceutical compositions have two big main advantages,
First, higher treatment level can be maintained in longer time, second is that can subtract while reaching with quick releasing formulation same effect
Few medicining times, to improve the compliance of patient.Slow release method is efficiently used, drug is implanted directly into lesions position, when long
Between be sustained drug effect, can not only mitigate the pain of patient, also can the release of more scientific and reasonable control drug effect.Wherein, hydrogel conduct
Pharmaceutical carrier plays an important role in terms of medicine controlled releasing.The response performance of hydrogel be by the reversible volumetric phase transformation of gel come
It realizes, and makes it in the fixation etc. of sensor, artificial muscle, drug controlled release, organizational project, catalyst system and catalyzing, enzyme
It has broad application prospects.
Currently, European and American developed countries have started the clinical application of similar technique many years ago.Such as chip implanted prosthetics, drug
It is big to be sustained side effect, silica gel stick technology is there are nondegradable defect, and patient must face the pain of second operation, and small plant
Enter in body technique, since release amount of medicine is uncontrollable, there is also huge side effects.And it is newest research shows that nanometer
Gel, which can be loaded, to be sent to inside cell and passes through biomembrane.This nanogel has good stability and can protect
Shield bioactie agent is not degraded by endocellular metabolism system.Nanogel conveys and improves oral and brain in systemic medication
Prodigious potential is shown in terms of the bioavilability of position.
Wherein, injection aquagel in situ is the novel hydrogels system occurred in recent years.To have by the method for injection
There is the biomaterial of certain fluidity to implant, therefore is easy to full of the entire defect with irregular shape, hand
Art wound is very small.And how to realize that the immune response that hydrogel must inject and reduce implantation material to skin is to realize this
The key of technology.
Utility model content
In view of the above-mentioned state of the art, the technical problem to be solved by the utility model is to provide a kind of reduction plants
Enter the storage unit of the injection-type Nano medication of object immune response.
Technical solution is used by the utility model solves above-mentioned technical problem：A kind of storage of injection-type Nano medication
Unit includes the nanogel in cylindrical structure, and the length of the nanogel of the cylindrical structure is 8mm.
Further, a diameter of 1mm of the nanogel of the cylindrical structure.
Further, it is embedded with drug in the nanogel.
It is the utility model compared with prior art that the utility model, which solves technical solution used by above-mentioned technical problem,
Advantageous effect be：Using the nanogel of cylindrical structure, on the one hand drug one easy to carry is logical is injected into the groups such as integumentary musculature
It knits, on the other hand can effectively reduce immune response of the human body to implantation material.
Description of the drawings
Fig. 1 is novel overall structure diagram described in the utility model.
Specific implementation mode
The following will be combined with the drawings in the embodiments of the present invention, to the skill embodiment in the utility model embodiment, and
The embodiment being not all of.Based on the embodiments of the present invention, those of ordinary skill in the art are not making creativeness
The every other embodiment obtained under the premise of labour, shall fall within the protection scope of the present invention.
As shown in Figure 1, a kind of storage unit of injection-type Nano medication, includes having uniform nano junction in cylindrical structure
The gel particle of structure is (referred to as：Nanogel), the length of the nanogel of the cylindrical structure is 8mm, the cylindrical structure
A diameter of 1mm of nanogel.
It is embedded with drug in the nanogel.
Its preparation process can be laser processing or 3D printing.
It is the utility model compared with prior art that the utility model, which solves technical solution used by above-mentioned technical problem,
Advantageous effect be：Using the nanogel of cylindrical structure, on the one hand drug one easy to carry is logical is injected into the groups such as integumentary musculature
It knits, on the other hand can effectively reduce immune response of the human body to implantation material.
It is obvious to a person skilled in the art that the present invention is not limited to the details of the above exemplary embodiments, and
And without departing substantially from the spirit or essential attributes of the utility model, it can realize that this practicality is new in other specific forms
Type.Therefore, in all respects, the present embodiments are to be considered as illustrative and not restrictive, this practicality is new
The range of type is indicated by the appended claims rather than the foregoing description, it is intended that containing in the equivalent requirements of the claims will be fallen
All changes in justice and range are embraced therein.Any reference numeral in claim should not be considered as limitation
Involved claim.
Claims (3)
1. a kind of storage unit of injection-type Nano medication, which is characterized in that include the nanogel in cylindrical structure, the circle
The length of the nanogel of rod structure is 8mm.
2. a kind of storage unit of injection-type Nano medication according to claim 1, which is characterized in that the cylindrical structure
Nanogel a diameter of 1mm.
3. a kind of storage unit of injection-type Nano medication according to claim 1, which is characterized in that the nanogel
Inside it is embedded with drug.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201721512720.1U CN207950204U (en) | 2017-11-06 | 2017-11-06 | A kind of storage unit of injection-type Nano medication |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201721512720.1U CN207950204U (en) | 2017-11-06 | 2017-11-06 | A kind of storage unit of injection-type Nano medication |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN207950204U true CN207950204U (en) | 2018-10-12 |
Family
ID=63724579
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201721512720.1U Active CN207950204U (en) | 2017-11-06 | 2017-11-06 | A kind of storage unit of injection-type Nano medication |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN207950204U (en) |
-
2017
- 2017-11-06 CN CN201721512720.1U patent/CN207950204U/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| He et al. | Intradermal implantable PLGA microneedles for etonogestrel sustained release | |
| KR101747099B1 (en) | Method of Preparing Micro-Needle Using Biocompatible Polymer | |
| AU2012247089B2 (en) | Microneedle assembly formulation for skin treatment | |
| KR100483447B1 (en) | Device for local administration of solid and semisolid formulations, sustained-release formulations for parenteral administration and method of preparation | |
| CN102657914A (en) | Micro-needle transdermal delivery patch with high penetration efficiency | |
| CN105411997A (en) | Degradable microstructure body and preparation method thereof | |
| EP3117867B1 (en) | Micro-needle preparation administration member for intradermal placement of target substance and apparatus for rapid administration of micro-needle preparation | |
| CN111904951A (en) | Microneedle patch and preparation method thereof | |
| Nguyen et al. | Advances of microneedles in hormone delivery | |
| CN106362223B (en) | Porous fibroin albumen micropin drug delivery device and preparation method thereof | |
| CN104519870B (en) | Injectable composition | |
| CN107096013A (en) | Salmon calcitonin solubility microneedle patch and preparation method thereof | |
| CN113081896A (en) | Regenerative medical injection for facial rejuvenation and application thereof | |
| CN115737782A (en) | Microneedle patch carrying melittin nanoparticles and/or antigens, preparation method and application | |
| CN102805896A (en) | Transdermal administration method, preparation and system | |
| CN114099936A (en) | Long-acting soluble microneedle for cosmetic filling and sustained-release administration and preparation method thereof | |
| CN207950204U (en) | A kind of storage unit of injection-type Nano medication | |
| KR20200108308A (en) | High-load microneedle and composition for skin enhancement | |
| CN208003121U (en) | A kind of storage unit for stablizing sustained release Nano medication | |
| CN208229126U (en) | A kind of storage unit of the Nano medication fixed convenient for implantation | |
| CN208611373U (en) | A kind of storage unit of the Nano medication convenient for operation | |
| CN103269693A (en) | Selective, lipophilic, and long-acting beta agonist monotherapeutic formulations and methods for the cosmetic treatment of adiposity and contour bulging | |
| JP2022500177A (en) | Microstructure-based drug injection device and its manufacturing method | |
| CN214158121U (en) | Long-acting intelligent implantable drug carrying device | |
| CN114848577A (en) | Double-layer conductive microneedle patch for treating subcutaneous tumors and preparation method and application thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant |