CN208582561U - A kind of Biodegradable tubular bracket of supersonic induced micro-embossing preparation - Google Patents

A kind of Biodegradable tubular bracket of supersonic induced micro-embossing preparation Download PDF

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Publication number
CN208582561U
CN208582561U CN201820150580.6U CN201820150580U CN208582561U CN 208582561 U CN208582561 U CN 208582561U CN 201820150580 U CN201820150580 U CN 201820150580U CN 208582561 U CN208582561 U CN 208582561U
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CN
China
Prior art keywords
bracket
tubular bracket
biodegradable tubular
biodegradable
mold
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Expired - Fee Related
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CN201820150580.6U
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Chinese (zh)
Inventor
岳军齐
杜建飞
石国宏
卞平艳
王建平
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Henan University of Technology
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Henan University of Technology
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Priority to CN201820150580.6U priority Critical patent/CN208582561U/en
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Publication of CN208582561U publication Critical patent/CN208582561U/en
Expired - Fee Related legal-status Critical Current
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Abstract

The utility model relates to a kind of Biodegradable tubular brackets of supersonic induced micro-embossing preparation.Specific steps are as follows: form a set of equipment with special die (2-1), ultrasonic vibrator (2-2), temperature controller (2-3), heating rod (2-4), pressing plate (2-5), power supply (2-6), pedestal (2-7) etc..The type that powder particle PPDO material is laid in mold is intracavitary, makes powder particle fast melt using ultrasonic vibration, and quickly fill with microlaser cavity.Mold is placed on pedestal, ultrasonic vibrator is fixed on mold, applies static pressure, opening ultrasonic vibration by heat preservation, pressure maintaining, cooling, die sinking, polishing and cleaning treatment finally can be obtained the biodegradable tubular bracket of micron level.The biodegradable tubular bracket of invention preparation is in addition to degradability, surface are smooth, its mechanical property shows anisotropic character, radial strength, axial elasticity are all greatly improved, and it improves the safety of use, preparation process is simple, is of great immediate significance to the clinical treatment of various pipelines.

Description

A kind of Biodegradable tubular bracket of supersonic induced micro-embossing preparation
Technical field
The present invention relates to a kind of Biodegradable tubular brackets of supersonic induced micro-embossing preparation, belong to artificial tubular The preparation field of bracket.
Background technique
The intracorporal pipeline of people is varied, such as esophagus, tracheae, blood vessel, nerve, common hepatic duct, urogenital pipe.When in human body These pipeline group hair-weavings sick change when, must just carry out corresponding treatment, carry out repairing replacement operation when necessary.Biodegradable Tubular bracket is to transplant object according to the pipeline of human body different parts, passes through the methods of physics, chemistry, biology by technical staff A kind of biodegradable tubular bracket being prepared.
Kinds of experiments shows that by biodegradable tubular bracket implantation pipeline be feasible, early clinic application result Be it is inspirer, by clinical test, tentatively embodied its superiority relative to permanent metal bracket.Biology can Tubular bracket development of degrading has important clinical meaning, it is desirable to which the biology for obtaining capableing of the perfect various demands for meeting clinic can Degradation tubular bracket, preparation facilities become particularly important.
The devices preparation such as current electrostatic spinning technique (CN105839204A) and three-dimensional micro-injection free forming technology Biodegradable scaffold have certain defect, be such as not enough to provide enough support forces, in the process of importing in radial strength In due to axial elasticity deficiency, cause bracket cracked etc..
Summary of the invention
It is an object of the invention to for existing biodegradable tubular bracket radial strength, in terms of Deficiency, propose the biodegradable tubular bracket and device of a kind of induction micro-embossing preparation of novel ultrasonic.So that this dress The shearing force that can apply specific direction for biodegradable tubular bracket under the induction of ultrasound during coining is set, is changed Become lattice form in stenting procedure, to make degradable intracavity stent that anisotropy be presented, while meeting in radial strength With the requirement of axial elasticity.
The solution of the present invention is specific as follows
A kind of Biodegradable tubular bracket, it is characterised in that biodegradable tubular bracket mesh is lattice shape , bracket expansion shape is rectangle, and one end is buckle, and bracket 0.15~0.25mm of integral thickness has groove in bracket on one side, Another side has a protrusion, and for bracket in curling, protrusion corresponds to groove, raised then be buckled on buckle when being crimped onto the last layer.Institute The biodegradable tubular bracket stated is made by degradable high molecular material.
The preparation facilities of a kind of Biodegradable tubular bracket of the present invention, it is characterised in that including walking as follows It is rapid:
(1) with special die (2-1), ultrasonic vibrator (2-2), temperature controller (2-3), heating rod (2-4), pressing plate (2-5), Power supply (2-6), pedestal (2-7) etc. form a set of equipment.It is connected shown in route by specification attached drawing 2, powers on switch, The temperature of temperature controller is set, and when temperature controller reaches setting value, the type that powder particle PPDO material is laid in mold is intracavitary.Benefit Make powder particle fast melt with ultrasonic vibration, and quickly fills with microlaser cavity
(2) mold is placed on pedestal, ultrasonic vibrator is fixed on mold, apply static pressure, keep static pressure not Become, while opening ultrasonic vibration, lattice form is had an impact using ultrasonic vibration shear action, after a period of time, closes super Sound keeps the temperature after ultrasonic vibration stopping and static pressure is kept then to pull out power switch for a period of time, protects to its cooled and solidified It is opened after staying corresponding crystalline state.By polishing and cleaning treatment, the biodegradable tubulose branch of micron level can be obtained Frame.(see Figure of description 1).
The novel biodegradable tubular bracket of one kind of the present invention, it is characterised in that: using passing through ultrasonic vibration The special crystal habit generated afterwards, so that the mechanical property of net grid support shows anisotropic character.
The preparation facilities of a kind of Biodegradable tubular bracket of the present invention, it is characterised in that: described is super Acoustic vibration be respectively X to, Y-direction, Z-direction, about the z axis the single dimension ultrasonic vibration shear action reversed or two kinds it is compound or three kinds Complex vibration.
The preparation facilities of a kind of New pipe biodegradable tubular bracket of the present invention, it is characterised in that: described The frequency of ultrasonic vibration is 20kHZ -70kHZ.
The present invention has substantive distinguishing features following prominent and significant technological progress compared with prior art
The present invention passes through the ultrasonic vibration in three directions, changes the radial shear power of biodegradable tubular bracket, so that The biodegradable tubular bracket of preparation radial strength, axial elasticity, in terms of than existing three-dimensional injection The biodegradable tubular bracket of the conventional apparatus such as free forming technology preparation has greatly improved.
The precision of biodegradable tubular bracket prepared by the present invention and clinical adaptability are certainly than existing three-dimensional micro-injection It is greatly improved by bracket prepared by forming technique.
Bracket of the biodegradable tubular bracket prepared by the present invention than existing three-dimensional micro-injection free forming technology preparation It is more solid, it is more firm in human body.
Biodegradable tubular bracket prepared by the present invention than existing three-dimensional micro-injection free forming technology preparation bracket, Stronger on product structure, more stable in quality, use is safer.
Branch of the biodegradable tubular bracket prepared by the present invention than existing three-dimensional micro-injection free forming technology preparation Frame is more advantageous to adherency, the increment of inner tube chrotoplast, hence it is evident that improve the effect of reparation.
Detailed description of the invention
Fig. 1 is biodegradable tubular bracket.
Fig. 2 is the system schematic of Biodegradable tubular bracket preparation facilities.
Specific embodiment
Below with reference to specific example, the present invention will be further described in detail, but the present invention is not limited to following implementations Example.
Embodiment one
(1) with special die (2-1), ultrasonic vibrator (2-2), temperature controller (2-3), heating rod (2-4), pressing plate (2-5), Power supply (2-6), pedestal (2-7) etc. form a set of equipment.Being connected shown in route by specification attached drawing 2, power on out It closes, the temperature that temperature controller is arranged is 80 DEG C -90 DEG C, and when temperature controller reaches setting value, powder particle PPDO material is laid in The type of mold is intracavitary.Make powder particle fast melt using ultrasonic vibration, and quickly fills with microlaser cavity
(2) mold is placed on pedestal, ultrasonic vibrator is fixed on mold, apply the static pressure of 100N-150N, protected It holds that static pressure is constant, while opening X to the ultrasonic vibration with Z-direction, shadow is generated to lattice form using ultrasonic vibration shear action It rings, after 3-5 minutes, closes ultrasound, after ultrasonic vibration stopping, keeping the temperature and keep static pressure 5-10 minutes, then pull out power supply Switch is opened after its cooled and solidified retains corresponding crystalline state.By polishing and cleaning treatment, micron level can be obtained Biodegradable tubular bracket.
Embodiment two
(1) with special die (2-1), ultrasonic vibrator (2-2), temperature controller (2-3), heating rod (2-4), pressing plate (2-5), Power supply (2-6), pedestal (2-7) etc. form a set of equipment.Being connected shown in route by specification attached drawing 2, power on out It closes, the temperature that temperature controller is arranged is 80 DEG C -90 DEG C, and when temperature controller reaches setting value, powder particle PPDO material is laid in The type of mold is intracavitary.Make powder particle fast melt using ultrasonic vibration, and quickly fills with microlaser cavity
(2) mold is placed on pedestal, ultrasonic vibrator is fixed on mold, apply the static pressure of 100N-150N, protected It holds that static pressure is constant, while opening the ultrasonic vibration of Y-direction and Z-direction, shadow is generated to lattice form using ultrasonic vibration shear action It rings, after 3-5 minutes, closes ultrasound, after ultrasonic vibration stopping, keeping the temperature and keep static pressure 5-10 minutes, then pull out power supply Switch is opened after its cooled and solidified retains corresponding crystalline state.By polishing and cleaning treatment, micron level can be obtained Biodegradable tubular bracket.
Embodiment three
(1) with special die (2-1), ultrasonic vibrator (2-2), temperature controller (2-3), heating rod (2-4), pressing plate (2-5), Power supply (2-6), pedestal (2-7) etc. form a set of equipment.Being connected shown in route by specification attached drawing 2, power on out It closes, the temperature that temperature controller is arranged is 80 DEG C -90 DEG C, and when temperature controller reaches setting value, powder particle PPDO material is laid in The type of mold is intracavitary.Make powder particle fast melt using ultrasonic vibration, and quickly fills with microlaser cavity
(2) mold is put into clamping device, fastens clamping device, apply static pressure, kept static pressure constant, open simultaneously Z-direction and the ultrasonic vibration reversed about the z axis have an impact lattice form using ultrasonic vibration shear action, after 3-5 minutes, close Ultrasound is closed, after ultrasonic vibration stopping, keeping the temperature and keeps static pressure 5-10 minutes, then pull out power switch, it is solidifying to its cooling Admittedly being opened after retaining corresponding crystalline state.By polishing and cleaning treatment, the biodegradable pipe of micron level can be obtained Shape bracket.
Example IV
(1) with special die (2-1), ultrasonic vibrator (2-2), temperature controller (2-3), heating rod (2-4), pressing plate (2-5), Power supply (2-6), pedestal (2-7) etc. form a set of equipment.Being connected shown in route by specification attached drawing 2, power on out It closes, the temperature that temperature controller is arranged is 80 DEG C -90 DEG C, and when temperature controller reaches setting value, powder particle PPDO material is laid in The type of mold is intracavitary.Make powder particle fast melt using ultrasonic vibration, and quickly fills with microlaser cavity
(2) mold is put into clamping device, fastens clamping device, apply static pressure, kept static pressure constant, open simultaneously X has an impact lattice form using ultrasonic vibration shear action, after 3-5 minutes, closes to, the ultrasonic vibration of Y-direction and Z-direction Ultrasound keeps the temperature after ultrasonic vibration stopping and keeps static pressure 5-10 minutes, then pull out power switch, to its cooled and solidified It is opened after retaining corresponding crystalline state.By polishing and cleaning treatment, the biodegradable tubulose of micron level can be obtained Bracket.
Embodiment five
(1) with special die (2-1), ultrasonic vibrator (2-2), temperature controller (2-3), heating rod (2-4), pressing plate (2-5), Power supply (2-6), pedestal (2-7) etc. form a set of equipment.Being connected shown in route by specification attached drawing 2, power on out It closes, the temperature that temperature controller is arranged is 80 DEG C -90 DEG C, and when temperature controller reaches setting value, powder particle PPDO material is laid in The type of mold is intracavitary.Make powder particle fast melt using ultrasonic vibration, and quickly fills with microlaser cavity
(2) mold is put into clamping device, fastens clamping device, apply static pressure, kept static pressure constant, open simultaneously The ultrasonic vibration that X is reversed to, Y-direction and about the z axis, has an impact lattice form using ultrasonic vibration shear action, 3-5 minutes Afterwards, ultrasound is closed, after ultrasonic vibration stopping, keeping the temperature and keeps static pressure 5-10 minutes, then pull out power switch, it is cold to its But solidification is opened after retaining corresponding crystalline state.It can be dropped by polishing and cleaning treatment, the biology that micron level can be obtained Solve tubular bracket.

Claims (1)

1. a kind of Biodegradable tubular bracket of supersonic induced micro-embossing preparation, it is characterised in that biodegradable tubulose Stent mesh is lattice shape, and bracket expansion shape is rectangle, and one end is to buckle, bracket integral thickness 0.15mm~ 0.25mm has groove in bracket on one side, and another side has protrusion, and for bracket in curling, protrusion corresponds to groove, and curling is to the end Raised then be buckled on buckle at one layer, the biodegradable tubular bracket is made by degradable high molecular material.
CN201820150580.6U 2018-01-30 2018-01-30 A kind of Biodegradable tubular bracket of supersonic induced micro-embossing preparation Expired - Fee Related CN208582561U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201820150580.6U CN208582561U (en) 2018-01-30 2018-01-30 A kind of Biodegradable tubular bracket of supersonic induced micro-embossing preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201820150580.6U CN208582561U (en) 2018-01-30 2018-01-30 A kind of Biodegradable tubular bracket of supersonic induced micro-embossing preparation

Publications (1)

Publication Number Publication Date
CN208582561U true CN208582561U (en) 2019-03-08

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Family Applications (1)

Application Number Title Priority Date Filing Date
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Country Status (1)

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CN (1) CN208582561U (en)

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Granted publication date: 20190308

Termination date: 20210130