CN208582459U - For endovascular medical device - Google Patents

For endovascular medical device Download PDF

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Publication number
CN208582459U
CN208582459U CN201820009031.7U CN201820009031U CN208582459U CN 208582459 U CN208582459 U CN 208582459U CN 201820009031 U CN201820009031 U CN 201820009031U CN 208582459 U CN208582459 U CN 208582459U
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China
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capsule
chamber
medical device
endovascular medical
endovascular
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CN201820009031.7U
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王国辉
王震
吴建平
薛宗玉
张坤
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Shanghai Xinwei Medical Technology Co.,Ltd.
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Shanghai Wei Wei Medical Technology Co Ltd
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Abstract

The utility model provides a kind of for endovascular medical device, including slender member, the slender member includes distal ports, described further includes the expandable capsule carried by the distal ports for endovascular medical device, the capsule at least has the first shape in contraction state and the second shape in swelling state, it is characterized in that, described is configured to for endovascular medical device, when the capsule is in the second shape, the capsule at least has first for being close to and blocking blood vessel with vascular wall to block outer surface and the second closure outer surface for being close to and blocking blood vessel with vascular wall;The first closure outer surface and the second closure outer surface are separated from each other in position.

Description

For endovascular medical device
Technical field
The utility model relates to one kind to be used for endovascular medical device, more particularly to one kind is able to achieve in a low voltage state The device that effective blood vessel blocks, can be used for temporary plugging vascular flow, absorbs vascular thrombosis by negative pressure or auxiliary is all kinds of takes bolt Instrument completes blood vessel machinery and takes bolt, or as other interposing catheters or the accessory channel of instrument etc., belongs to medical device technology neck Domain.
Background technique
The intravascular intervention diagnosing and treating therapeutic modality minimally invasive as one, recently as iconography equipment into The introducing improvement of step, novel intervention equipment is quickly developed, and blood vessel intervention doctor, which can handle, to become increasingly complex The case of lesion, clinical application is more and more, and the disease being related to is also more and more extensive.However, what is faced at present is one of difficult To solve the problems, such as to be, conduit is operated in the blood vessels or generates clast bolt when conveying the sacculus, bracket or plugging device of interventional therapy Subflow causes distal vessels to occlude to blood vessel distal end.
The interventional technique of the cranial vascular disease minimally-invasive treatment mode representative as one, recently as iconography The progress of equipment, the introducing of novel intervention equipment are quickly developed, and cranial nerve intervention doctor can handle increasingly Complicated lesion, the case of clinical application is more and more, and the disease being related to is also more and more extensive.
The machinery of bolt instrument is taken to take bolt or lead using sacculus by balloon guide catheter conveying intervention in the cerebrovascular The treatment method that pipe completes to inhale bolt has many advantages, such as that bleeding is few, wound is small, few intercurrent disease, safe and reliable, post-operative recovery is fast, becomes The bright spot of acute ischemic cerebral apoplexy treatment, there is revascularization rate more higher than vein or Arterial thrombolysis and broader treatment time Window.
Report in " acute ischemic cerebral apoplexy China Consensus of experts 2017 editions ", the key for taking bolt access to select be whether Use balloon guide catheter and centre/suction catheter;NASA registration research is included in 138 of 24 centers altogether and uses sacculus The patient of guiding catheter, compared with unused balloon guide catheter person, user's recanalization rate is higher, distal embolization rate and Dystopy thrombosis rate indifference, clinical prognosis desirable rate is high within 3 months;Multinomial logistic regression shows using balloon guide catheter It is the good independent influencing factor of clinical prognosis.MCA can be significantly improved using the Solumbra technology that intermediate conductor assists to close Plug machinery takes the success rate of bolt, reduces distal embolization rate and dystopy thrombosis rate.Experiment in vitro further confirms that bracket takes bolt to combine Centre/suction catheter suction can reduce hard and crisp thromboembolism distal vessels event, and joint balloon guide catheter can be significant The distal embolization event of fresh red thrombus is reduced, therefore balloon guide catheter is used in combination in embolectomy and centre/suction catheter can There can be clinical meaning.
Balloon guide catheter usage mode are as follows: by the interventional procedure of standard, percutaneous puncture is placed in arterial sheath, and auxiliary takes bolt device Tool reaches vascular thrombosis proximal end, so that it is attached at vascular wall by balloon inflation, temporary interruption blood flow forms partial sealing;? Under external negative pressure cooperation, bolt instrument and thrombus will be taken to adsorb the inner cavity into conduit.Then the sacculus for shrinking balloon guide catheter, is returned Balloon guide catheter is removed, takes thrombus out of human body to achieve the purpose that blood flow is rebuild.
Balloon guide catheter auxiliary intervention apparatus complete machinery take bolt or individually inhale bolt critical issue be: 1, sacculus compared with Under small filling pressure, it can be realized validity closure, reduce the stimulation to cranial nerve vascular wall;2, and sacculus position has Developing mark, the position of sacculus can be accurately positioned in doctor in interventional procedure;3, conduit itself should have preferable flexibility, Diseased region can be smoothly reached by full of twists and turns blood vessel.
Country's commercialized product is the Merci balloon guide catheter of U.S. Concentric Medical company production at present. Its disadvantage are as follows: sacculus is larger with blood contacting surface, more to vascular stimulation, easily causes the complication such as spasm.
Therefore, those skilled in the art is dedicated to developing a kind of new for endovascular medical device.
Utility model content
In view of the above drawbacks of the prior art, the utility model provides the new endovascular medical treatment that is used for of one kind and fills It sets, technical problem to be solved in the utility model is the contact surface reduced between capsule and blood vessel.
To achieve the above object, the technical solution of the utility model are as follows: one kind is used for endovascular medical device, including thin Long component, the slender member include distal ports, and described further includes being taken by the distal ports for endovascular medical device The expandable capsule of band, the capsule at least have the first shape in contraction state and the second shape in swelling state, Described is configured to for endovascular medical device, and when the capsule is in the second shape, the capsule, which at least has, to be used for It is close to and blocks the first closure outer surface of blood vessel with vascular wall and second for being close to and blocking blood vessel with vascular wall blocks Outer surface;The first closure outer surface and the second closure outer surface are separated from each other in position.
Preferably, described is balloon guide catheter for endovascular medical device.
Preferably, when the capsule is in the second shape, the shape of the capsule is Pear-Shaped.
Preferably, the capsule is configured as, and when by the bulbs of pressure, the first of the capsule blocks outer surface and the second envelope The part and second that the expansion amplitude of part between stifled outer surface is less than the first closure outer surface of the capsule blocks outer surface Part expansion amplitude.
Preferably, the endovascular medical device that is used for is configured to: when it is 7mm that the capsule, which is expanded into outer diameter, The length of the capsule is not more than 14mm.
Preferably, the endovascular medical device that is used for is configured to: when it is 9mm that the capsule, which is expanded into outer diameter, The length of the capsule is not more than 16mm.
Preferably, the endovascular medical device that is used for is configured to: being 10mm when the capsule is expanded into outer diameter When, the length of the capsule is not more than 18mm.
Preferably, the slender member further includes interlude, the distal ports and the interlude have prolong it is described thin The first chamber and the second chamber that the axis of long component extends.
Preferably, the distal ports include distal ports outer tube and distal ports inner tube, and the interlude includes interlude outer tube With interlude inner tube;First chamber includes the inner cavity of the distal ports inner tube and the inner cavity of interlude inner tube, second chamber Outer wall including the distal ports inner tube and the space between the inner wall of the distal ports outer tube and the interlude inner tube Space between outer wall and the inner wall of the interlude outer tube.
Preferably, the slender member further includes proximal segment, and the proximal segment includes proximal segment outer tube and proximal segment inner tube; First chamber includes the inner cavity of the proximal segment inner tube, and second chamber includes the outer wall of the proximal segment inner tube and described close Hold the space between the inner wall of section outer tube;Described further includes the hand connecting with the proximal segment for endovascular medical device Handle.
Preferably, the endovascular medical device that is used for is configured to, described when the capsule is in the second shape There is third chamber between the outer wall of distal ports outer tube and the capsule, the distal ports outer tube has one or more holes, and described the Three chambers are connected to by the hole with second chamber.
Preferably, the endovascular medical device that is used for is configured to, described when the capsule is in the second shape There is the 4th chamber between the outer surface and blood vessel of capsule.
Preferably, the capsule includes the first capsule portion and the second capsule portion, and first closure outer surface is located at first capsule Portion, second closure outer surface are located at second capsule portion;Described is configured to for endovascular medical device, works as institute When stating capsule and being in the second shape, between first capsule portion and the outer wall of the slender member there is third chamber first to divide chamber, institute Stating between the second capsule portion and the outer wall of the slender member, there is third chamber second to divide chamber;The slender member has one or more A hole, the third chamber first divide chamber to be connected to by the hole with second chamber, and the third chamber second divides chamber by addition The hole be connected to second chamber;The third chamber first divides chamber and third chamber second to divide chamber mutually indepedent.
Preferably, first capsule portion and the second capsule portion are manufactured separately, and are individually connected to the distal ports The outer wall of outer tube.
Preferably, first capsule portion and the second capsule portion are manufactured into one, and are coupled together to outside the distal ports The outer wall of pipe.
Preferably, described for endovascular medical device further includes the marker that can be shown under ray, it is close or It is close to the proximal end and/or distal end of the capsule.
Preferably, the marker is ring-type, is socketed in the outside of the slender member.
Preferably, described further includes the marker that can be shown under ray, the mark for endovascular medical device Remember that object is the developing material being embedded in the cyst wall of the capsule.
Preferably, also there is the capsule third for being close to and blocking blood vessel with vascular wall to block outer surface, and described the One closure outer surface, the second closure outer surface and third block outer surface and are separated from each other in position.
Preferably, when the capsule is in the second shape, the shape of the capsule is calabash bunch shape.
Preferably, the endovascular medical device that is used for is configured to: when it is 7mm that the capsule, which is expanded into outer diameter, The length of the capsule is not more than 21mm.
Preferably, the endovascular medical device that is used for is configured to: when it is 9mm that the capsule, which is expanded into outer diameter, The length of the capsule is not more than 24mm.
Preferably, the endovascular medical device that is used for is configured to: being 10mm when the capsule is expanded into outer diameter When, the length of the capsule is not more than 27mm.
The advantageous effects of the utility model are as follows: capsule is designed as two-part or multisection type, can play identical closure Effect, and can be reduced the stimulation to blood vessel, reduce the generation of complication.
Make furtherly below with reference to technical effect of the attached drawing to the design of the utility model, specific structure and generation It is bright, to be fully understood from the purpose of this utility model, feature and effect.
Detailed description of the invention
Fig. 1 is the first preferred embodiment provided by the utility model for endovascular medical device Structure section schematic diagram.
Fig. 2 is the structure section schematic diagram of the interlude of the slender member shown in FIG. 1 for endovascular medical device.
Fig. 3 is that the distal ports of the slender member shown in FIG. 1 for endovascular medical device and the structure of top section are cut Face schematic diagram (capsule is in contraction state).
Fig. 4 is that the distal ports of the slender member shown in FIG. 1 for endovascular medical device and the structure of top section are cut Face schematic diagram (capsule is in swelling state).
Fig. 5 is that the distal ports of the slender member shown in FIG. 1 for endovascular medical device and the structure of top section are cut Face schematic diagram (being encapsulated stifled blood vessel of expansion).
Fig. 6 is the proximal segment of the slender member shown in FIG. 1 for endovascular medical device and the structure section of handle Schematic diagram.
Fig. 7 is second of preferred embodiment provided by the utility model for endovascular medical device Structure section schematic diagram.
Fig. 8 is the third preferred embodiment provided by the utility model for endovascular medical device Structure section schematic diagram.
Fig. 9 is the 4th kind of preferred specific embodiment party provided by the utility model for endovascular medical device The structure section schematic diagram of formula.
Specific embodiment
Multiple preferred embodiments that the utility model is introduced below with reference to Figure of description, keep its technology contents clearer Be easy to understand.The utility model can be emerged from by many various forms of embodiments, the protection of the utility model Range is not limited only to the embodiment mentioned in text.
In the accompanying drawings, the identical component of structure is indicated with same numbers label, everywhere the similar component of structure or function with Like numeral label indicates.The size and thickness of each component shown in the drawings are to be arbitrarily shown, and the utility model is not Limit the size and thickness of each component.Apparent in order to make to illustrate, some places suitably exaggerate the thickness of component in attached drawing.
The term in term as used herein " proximal end " or similar description direction should be appreciated that are as follows: device or component Close to one end of the target position of user (or handle) or separate blood vessel to be treated;Term as used herein " distal end " Or the term in similar description direction should be appreciated that are as follows: the separate user (or handle) of device or component or close to needing to locate One end of the target position of the blood vessel of reason.Term as used herein " close end " should be appreciated that are as follows: lean in device or component Close or adjacent proximal ends a part (being not required for certain adjacent proximal ends);Term as used herein " distal portion " should be appreciated that Are as follows: close in device or component or a part (being not required for centainly close to distal end) close to distal end.
Term as used herein " balloon guide catheter " should be appreciated that are as follows: including elongated guiding catheter, and remote What end carried expandable capsule protrudes into endoceliac device.The meaning of " guiding catheter " meaning in " balloon guide catheter " Think of is, which can be transported to target position for other medical instruments (for example, the instrument for removing thrombus) or reagent, that is, Play the role of " guiding ";It should be noted that not needing by other for directly removing the medical instrument of obstruction, the device It itself can also implement the operation (for example, by negative-pressure ward thrombus) of removal body cavity internal congestion.Therefore, " balloon guide catheter " It is understood not to that the device of body cavity internal congestion must could be removed by other medical instruments.
It is preferred specific that Fig. 1-Fig. 6 shows the first for endovascular medical device provided by the utility model Embodiment.
As shown in figs 1 to 6, the device in the specific embodiment is used for from intravascular removal thrombus, object and/or resistance Plug property substance, a kind of most typical application are to remove thrombus.The device includes slender member 100, by the remote of slender member 100 The handle 300 of the expandable capsule 200 and the proximal segment positioned at slender member of holding section to carry.The device can be in many ways It is operated, for executing various processing functions or other functions in the blood vessels.For example, the device can with the first mode into Row operation, minimizes the shape of the device, consequently facilitating importing to endovascular target position;The device can also be with second Kind mode is operated, for example, with the instrument of removing thrombus will be gone to reach target thrombi, and the instrument after removal thrombus is inhaled Into inner cavity;The device can also be operated with the third mode, for example, blood vessel internal congestion is removed for directly suction, such as Thrombus;The device can also be operated with the 4th kind of mode, for example, balloon expandable Basilar artery blood flow, and carry out blood vessel and make Shadow.
The generally elongated shape of slender member 100, including proximal segment 110, interlude 120, distal ports 130, top section 140. Interlude 120, distal ports 130 and top section 140 be sized to import it is intravascular, proximal segment 110, interlude 120, Distal ports 130, top section 140 have the first interconnected chamber 510 extended along its axis.First chamber 510 is for directly inhaling It takes and removes blood vessel internal congestion, such as thrombus, or be sent to target site with by the instrument for removing obstruction, and after removing and blocking Instrument sucking, or pass through channel for other instruments.
As shown in Fig. 2, interlude 120 includes the interlude outer tube 121 and interlude inner tube 122 along the extension of same axis, First chamber 510 is the inner cavity of interlude inner tube 122.Have between interlude outer tube 121 and interlude inner tube 122 along interlude The second chamber 520 that 120 axis extends.Device in the specific embodiment is mainly used for removing the thrombus of intracranial vessel, because This, the length of interlude 120 can be 30 centimetres -160 centimetres, and the outer diameter of interlude outer tube 121 can be 1.5 millimeter of -4.0 milli Rice, the diameter of the first chamber 510 can be 0.8 millimeter -3.5 millimeters.In view of interlude outer tube 121 and interlude inner tube 122 The space of necessary thickness and enough second chambers 520, the internal diameter (i.e. the outer diameter of the second chamber 520) of interlude outer tube 121 can be with It is 1.45-3.95 millimeters, the outer diameter (i.e. the internal diameter of the second chamber 520) of interlude inner tube 122 can be 1.43-3.93 millimeters.
The main function of interlude 120 is the target position that distal ports 130 and top section 140 are delivered to blood vessel, and The second chamber 520 is provided to transmit the pressure for expanding capsule 200, therefore the configuration of interlude 120 mainly considers its mechanical property.In Between section outer tube 121 and interlude inner tube 122 can have substantially consistent structure along its axis, alternatively, structure can also become Change.For example, interlude outer tube 121 and the close end of interlude inner tube 122 can be it is substantially rigid or semirigid, thus just It is pushed ahead in the blood vessels in slender member 100, without having very big kink or curved risk;And interlude outer tube 121 It is then more flexible with the distal portion of interlude inner tube 122, to be suitable for curved blood vessel.Interlude outer tube 121 and interlude Inner tube 122 can use identical material, alternatively, different materials can also be used.For example, the material of interlude outer tube 121 Select plastics, the material selection metal or alloy of interlude inner tube 122;Alternatively, interlude outer tube 121 and interlude inner tube 122 Material all select metal or alloy woven network tube.What is had disclosed at present is suitable for interlude outer tube 121 and interlude inner tube 122 material and configuration can equally be well applied to the utility model and present embodiment, for example, U.S. Concentric The interlude outer tube and interlude inner tube of the Merci balloon guide catheter of Medical company production, here, being no longer described in detail.
As shown in figure 3, distal ports 130 include distal ports outer tube 131 and distal ports inner tube 132, the first chamber 510 is distal ports The inner cavity of inner tube 132, that is to say, that the first chamber 510 extends to distal ports 130 from interlude 120 along its axis.Outside distal ports The second chamber 520 that there is the axis of distally section 130 to extend between pipe 131 and distal ports inner tube 132, that is to say, that the second chamber 520 extend to distal ports 130 from interlude 120 along its axis.Expandable capsule 200 is located at the outside of distal ports outer tube 131. As a preferred mode, the outer diameter of distal ports outer tube 131 can be suitably less than the outer diameter of interlude outer tube 121, in this way, working as When capsule 200 is shunk, the outer diameter of the outer diameter in the capsule portion of device and entire endovascular part be it is the same or smaller, convenient for blood The intravascular part of circulation and device is moved in the blood vessels.Distal ports outer tube 131 and distal ports inner tube 132 can use and centre Section outer tube 121 and the identical material of interlude inner tube 122, for example, directly as interlude outer tube 121 and interlude inner tube 122 Extended segment;Distal ports outer tube 131 and distal ports inner tube 132 can also use and interlude outer tube 121 and interlude inner tube 122 different materials, for example, comparing interlude outer tube 121 and interlude inner tube 122, distal ports outer tube 131 and distal ports inner tube 132 use more rigid material.These are also all technologies known in the art, and this will not be detailed here.
Fig. 3-Fig. 5 shows the distal ports 130 and capsule 200 of the slender member 100 in the specific embodiment.In Fig. 3 In, capsule 200 is in the first shape of contraction state;In Fig. 4, capsule 200 is in the second shape of swelling state;In Fig. 5, capsule 200 are in the second shape of swelling state, and block blood vessel.
As shown in Figure 3 and Figure 4, capsule 200 includes proximal end interconnecting piece 210, distal connection 220 and inflatable portion 230.Proximal end The effect of interconnecting piece 210 and distal connection 220 is exactly to connect with distal ports 130 and/or top section 140, so that third chamber 530 Relative to the outer closures of capsule 200, so that inflatable portion 230 is expanded under the effect of the pressure.The proximal end interconnecting piece of capsule 200 210 and distal connection 220 and distal ports 130 and/or top section 140 connection type can there are many, for example, can be by viscous Mixture bonding, interference fit, laser welding, sound wave welding, melting, closely noose, by other connectors (such as lock ring, Wire or high score sub-line bind) it is closely bonded or/and the modes such as adhesive bonding is cooperated to be attached.
It is inflatable when pressure of the capsule 200 by medial surface, that is to say, that capsule 200 at least have that there are two types of shapes, i.e., in receipts The first shape (Fig. 3) of contracting state and the second shape (Fig. 4 and Fig. 5) in swelling state.When capsule 200 is in first shape When, slender member 100 and capsule 200 are suitble to move in the blood vessels as a whole;When capsule 200 is in the second shape, capsule 200 is played Block the effect of blood vessel.
When capsule 200 is in swelling state, inflatable portion 230 is with having third chamber 530 between distal ports outer tube 131.The It is connected between three chambers 530 and the second chamber 520 by one or more holes 133 on distal ports outer tube 131, so that from handle 300 pressure is transmitted to bulge 230 between distal ports outer tube 131 by the second chamber 520 so that capsule 200 carry out it is swollen It is swollen.The pressure that capsule 200 is expanded is hydraulic or air pressure, preferably hydraulic (such as developer or physiological saline). Capsule 200 can be made up of single tubular material of molding, blowing or other means.The proximal end interconnecting piece 210 of capsule 200 and distal end Interconnecting piece 220 can be sufficiently thick and/or rigid sufficiently strong, to provide enough sealing functions;And inflatable portion 230 can compare Proximal end interconnecting piece 210 and distal connection 220 are made thinner, shape when in order to provide desired expansion.Alternatively, capsule 200 Proximal end interconnecting piece 210, distal connection 220 and inflatable portion 230 or same thickness in this case can also To provide the shape of desired expansion.
Capsule 200 can be made of elastic material, such as compliance or semi-compliant capsule.Compliance or semi-compliant capsule can be with Sizes and/or shape are launched into according to the amount of the fluid in third chamber 530 and/or pressure.Capsule 200 can also be by basic Inelastic material is made, for example, non-compliance capsule, unfolded to predetermined size when inflated, it is unrelated with pressure (to work as addition Minimum volume and/or pressure are come after reaching predetermined size).One benefit of non-compliance capsule is, even if using relatively high pressure Power, capsule 200 expand when be not more than predetermined size, just will not generate in this way it is to blood vessel it is not expected that stronger pressure Compel.One benefit of compliance capsule is that, when the pressure for expanding capsule 200 is released, capsule 200 may be collapsed to abutting distal ports The outer wall of outer tube 131, so that the outer diameter in the capsule portion of whole device is as small as possible, convenient for the circulation of blood and the blood vessel of device Inner part moves in the blood vessels.The preferred compliance capsule of the specific embodiment, such as be made of the materials such as silica gel, PU, TPU.
As shown in Figure 4 and Figure 5, in this specific embodiment, when the inflatable portion 230 of capsule 200 is in swellable state When, inflatable portion 230 has the position that blood vessel can be blocked at two.Because blocking the outer surface mainly by inflatable portion 230 and blood Inside pipe wall 400 fits closely to realize, therefore, inflatable portion 200 has the first envelope for being close to and blocking blood vessel with vascular wall Outer surface 231 and the second closure outer surface 232 for being close to and blocking blood vessel with vascular wall are blocked up, first blocks outer surface 231 It is separated from each other in position with the second closure outer surface 232, that is to say, that first, which blocks outer surface 231 and second, blocks appearance There is the 4th chamber 540 between face 232 and the blood vessel 400 being close to.The shape of Fig. 4 and capsule shown in fig. 5 200 generally cucurbit Shape.So-called " Pear-Shaped " refers to be, from the appearance, there are two the parts of sphere or approximate spheres for the main body of capsule 200.Cucurbit The capsule of shape may be more easier in manufacture than other shapes, it will be clear that according to the principle that the specific embodiment provides, capsule 200 may be other shapes.For example, first block outer surface 231 and second block outer surface 232 closer to plane without It is spherical surface.
Compared with the existing technology, the device in the specific embodiment using at two in position separated position come Blood vessel is blocked, benefit is to mitigate the compressing and stimulation to blood vessel, to reduce the generation of complication.
For example, typically, the internal diameter for needing to handle the blood vessel of thrombus is about 6mm to one kind.In existing skill In art, capsule 200 only has position at one to block blood vessel, for example, coming from shape, entire only one sphere of capsule 200.This In the case of, in order to reach desired plugging effect, when capsule is in the second shape of expansion, the outer diameter of capsule would generally reach 7mm or so, the length of capsule would generally reach 8mm or so, and the area of plugging surface is usually 311mm2Left and right.In this way, capsule is to blood vessel The compressing and stimulation of inner wall are stronger, are easy to produce complication.
In this specific embodiment, blood vessel is blocked using position at two, than one at the efficiency that blocks of position improve Very much, the outer diameter, width and area of plugging surface can be greatly reduced in this way, to greatly reduce the pressure to blood vessel It forces to make peace stimulation.The application utility model people it was unexpectedly observed that for typically be about 6mm vessel diameter, when capsule 200 expand To outer diameter be 7mm when, if configuring 10-14mm for the length of capsule 200 can be realized ideal plugging effect.At this moment, first The area for blocking one in outer surface 231 and the second closure outer surface 232 is about 100~160mm2.The application's is practical new Type people is it has furthermore been found that the blood vessel bigger for internal diameter, for example, when it is 9mm that capsule 200, which is expanded into outer diameter, if by capsule 200 Length be configured to 10-16mm, ideal plugging effect can be realized;When it is 10mm that capsule 200, which is expanded into outer diameter, if by capsule 200 length is configured to 10-18mm, and ideal plugging effect can be realized.In the prior art, single plugging surface vascular compression A certain continuous position, it is larger to vascular stimulation;And multiple bag pressures compel the different location in blood vessel, reduce the continuous thorn to blood vessel Swash, blood vessel stress reaction is reduced, to reduce complication.
For compliance capsule, it is desirable to be expanded into desired Pear-Shaped, can configure capsule 200 makes the dilatancy at in-between position It is poor, for example, the wall at intermediate position is thicker, alternatively, the material poor using dilatancy, develops alternatively, being embedded at intermediate position Material (such as barium salt (BaSO4), bismuth salt (BiOCl etc.) etc.) etc..
In this specific embodiment, which further includes marker 240.The effect of marker 240 be ray (such as X-ray) under show the position of capsule 200, the preferable or more stable metal or metal alloy of biocompatibility, example can be selected in material Such as platinum group metal (such as platinumiridio), gold are addition developing material (such as barium salt (BaSO4), bismuth salt (BiOCl Deng) etc.) high molecular material.Alternatively, can also may be addition developing material (such as barium salt (BaSO4 with the material of capsule 200 Deng), bismuth salt (BiOCl etc.) etc.) high molecular material.
In this specific embodiment, as shown in Figures 4 and 5, marker 240 is ring-type, is socketed on distal ports outer tube 131 Outer wall, also, marker 240 is between capsule 200 and distal ports outer tube 131, that is to say, that when capsule 200 is in expansion shape body When, marker 240 is located at the inside of third chamber 530.It will be apparent that the deformation as the specific embodiment, is socketed on distal ports The cricoid marker 240 of the outer wall of outer tube 131 can also be located at the outside of third chamber 530, for example, the position other than capsule 200 It sets.Alternatively, marker 240 can also directly be socketed on capsule 200 proximal end interconnecting piece 210 and/or distal connection 220 it is outer Face, in this case, marker 240 are also used as lock ring, help between capsule 200 and the outer wall of distal ports outer tube 131 Closed connection.Either it is located at the outside of third chamber 530, or positioned at the inside of third chamber 530, marker 240 is preferably both Both ends that are close or being close to capsule 200, that is to say, that close or abutting proximal end interconnecting piece 210 and distal connection 220.In the tool In body embodiment, there are two ring-shaped mark objects 240 altogether, are close to proximal end interconnecting piece 210 and distal connection 220 respectively.This The configuration of sample can most clearly show the position of capsule 200 under ray.It will be apparent that the deformation as the specific embodiment, Ring-shaped mark object 240 also can be set more, for example, corresponding position configures ring at its maximum outside diameter when capsule 200 expands Shape marker.
As shown in figure 3, in this specific embodiment, top section 140 has the first chamber 510, that is to say, that the first chamber 510 extend to top section 140 from distal ports 130 along its axis.Distal end namely the first chamber of first chamber 510 of top section 140 510 openings towards internal tube, thrombus and/or other instruments for removing thrombus just pass in and out the first chamber 510 from the opening. The top for functioning as slender member 100 of top section 140, proximal end and distal ports outer tube 131 and distal ports inner tube 132 Distal end connection.The material preferred hardness of top end part 140 is smaller but has the material of certain elasticity;To be pushed away in slender member There is better protection to blood vessel when entering the bending section in blood vessel;Specific material such as Pebax2533, Pebax3533, TPU3585A and TPU3595A etc..In order to allow operator that can judge the position of the device in the blood vessels, top end part 140 can also With setting flag object, such as the metal or metal alloy that biocompatibility said before is preferable or more stable, such as platinum family Metal (such as platinumiridio), gold or the material of top end part 140 are addition developing material (such as barium salt (BaSO4), bismuth salt (BiOCl etc.) etc.) high molecular material.When the manufacturing, top section 140 and distal ports outer tube 131 and/or distal ports inner tube 132 can be manufactured separately, and be then connected to together;Top section 140 and distal ports outer tube 131 and/or distal ports inner tube 132 also can be made into one.
As shown in fig. 6, in this specific embodiment, proximal segment 110 includes proximal segment outer tube 111 and proximal segment inner tube 112, the first chamber 510 is the inner cavity of proximal segment inner tube 112, that is to say, that along its axis, proximally section 110 extends the first chamber 510 To interlude 120.There is second that the axis along proximal segment 110 extends between proximal segment outer tube 111 and proximal segment inner tube 112 Chamber 520, that is to say, that proximally section 110 extends to interlude 120 to the second chamber 520 along its axis.
The main function of proximal segment 110 is exactly to connect handle 300, and provide 510 He of the first chamber for being derived from handle 300 The channel of second chamber 520.As shown in fig. 6, handle is used to holding and operating whole device, for example, by slender member 100 and capsule 200 are pushed to endovascular target position.Handle at least has there are two mutually isolated chamber, a chamber and slender member 100 First chamber 510 connection, for removing thrombus;Another chamber is connected to the second chamber 520 of slender member 100, for providing pressure So that the expansion of capsule 200 and removal pressure shrink capsule 200.In order to complete this function, handle 300 need by interface with Other device connection, for example, generate the device (such as syringe, full device, vacuum pump, be used for the first chamber 510) of negative pressure with And provide hydraulic or air pressure device (such as syringe, full device are used for the second chamber 520).Proximal segment 110 and handle 300 are matched Setting is all technology known in the art, and this will not be detailed here.
Can directly be protruded into from skin through puncture or notch for endovascular medical device in the specific embodiment It is intravascular, alternatively, the device also using one or more other instruments enter it is intravascular, for example, guide sheath (leading by conduit and capsule Draw and pass through inside sheath or guide sheath is passed through conduit first is intracavitary), (conduit and capsule pass through guide wire outside guide wire, lead It is intracavitary positioned at first to draw silk).The position that marker 240 is monitored under the irradiation of ray promotes injection after reaching target position Device provides hydraulic or air pressure and capsule 200 is made to expand and block blood vessel, and remove the operation of thrombus, for example, opening vacuum pump Aspirate thrombi.After completing suction, pumpback syringe makes liquid or gas backstreaming in the second chamber 520, so that capsule 200 be made to receive Contracting.Finally by whole device from intravascular extraction.It in the process, can also be by 510 delivery of therapeutic agents of the first chamber to intravascular Target position, alternatively, conveying for directly removal thrombus other instruments.
Fig. 7 shows second for endovascular medical device provided by the utility model and is preferably embodied Mode.
Device and the slender member 100 of the first specific embodiment and the knot of handle 300 in the specific embodiment Structure is identical, primary difference is that the structure of capsule 200.
In this specific embodiment, equally also there are two types of shapes for tool for capsule 200, that is, are in the first shape of contraction state (not shown) and the second shape (Fig. 7) in swelling state.Similarly, when capsule 200 is in first shape, elongated structure Part 100 and capsule 200 are suitble to move in the blood vessels as a whole;When capsule 200 is in the second shape, capsule 200 plays closure blood vessel Effect.
Capsule 200, which equally also has, to be close to and is blocked with vascular wall the first of blood vessel and block outer surface 231 and be used for and blood vessel Wall is close to and blocks the second closure outer surface 232 of blood vessel, related first envelope provided in the first specific embodiment The shape and size of stifled outer surface 231 and the second closure outer surface 232 are also applied for the specific embodiment.
With the first specific embodiment the difference is that the capsule 200 in the specific embodiment divides for the first capsule portion 201 With the second capsule portion 202.Wherein, the first closure outer surface 231 is located at the first capsule portion 201, and second blocks outer surface 232 positioned at the Two capsule portions 202.When the first capsule portion 201 is in swelling state, the first capsule portion 201 is with having third between distal ports outer tube 131 Chamber first divides chamber 531;When the second capsule portion 202 is in swelling state, the second capsule portion 202 between distal ports outer tube 131 with having Third chamber second divides chamber 532.Third chamber first is divided to chamber 531 and third chamber second that chamber 532 is divided to be independent from each other two chambers, With regard to saying, the first capsule portion 201 and the second capsule portion 202 by third chamber first divide chamber 531 and third chamber second divide chamber 532 closely every From at two chambers.Third chamber first divides between chamber 531 and the second chamber 520 through the hole connection on distal ports outer tube 131, third Chamber second divides between chamber 532 and the second chamber 520 to be connected to also by the other hole on distal ports outer tube 131, so that from hand The pressure of handle 300 is transmitted to bulge 230 between distal ports outer tube 131, so that the first capsule portion by the second chamber 520 201 and second capsule portion 202 expanded.It is therefore, mentioned here that " third chamber first divides chamber and third chamber second to divide chamber mutually only It is vertical " refer to be not third chamber first divide chamber and third chamber second divide between chamber and be not connected to (they by the second chamber 520 indirectly Connection), but for capsule 200 itself, third chamber first is divided to chamber and third chamber second that the wall of chamber tunica is divided to be divided into two solely Vertical chamber.So that the pressure that the first capsule portion 201 and the second capsule portion 202 are expanded can be equally hydraulic or air pressure, preferably Air pressure.
It is that manufacture is relatively easy by the benefit that capsule 200 is divided into the first capsule portion 201 and the second capsule portion 202.At the first In specific embodiment, the generally Pear-Shaped of capsule 200, when capsule 200 is in contraction state, capsule 200 is tight as far as possible It pastes the outer wall of distal ports outer tube and makes the outer diameter of capsule 200 as small as possible, to move in the blood vessels;When capsule 200 is in swollen When swollen state, capsule 200 should be expanded into desired Pear-Shaped;It realizes this point, either uses elastic material or non-ballistic Property material, cost of manufacture are generally relatively high.In this specific embodiment, capsule 200 is separated out 201 He of independent first capsule portion Second capsule portion 202, in the expanded state, the first capsule portion 201 and the second capsule portion 202 only need to be expanded into almost spherical, Realize that this point is easily more than the first specific embodiment.During fabrication, the first capsule portion 201 and the second capsule portion 202 can To be manufactured separately, it is then respectively connected to the outer wall of distal ports outer tube.That is to say, the first capsule portion 201 and the second capsule portion 202 are respectively provided with respective proximal end interconnecting piece, distal connection and inflatable portion.In this case, the first capsule portion 201 and Two capsule portions 202 can be considered as two independent capsules in fact.First capsule portion 201 and the second capsule portion 202 can also be manufactured into one Body, and it is coupled together to the outer wall of distal ports outer tube.That is to say, the first capsule portion 201 and the second capsule portion 202 are as a whole With proximal end interconnecting piece, distal connection, middle interconnecting piece (the first capsule portion 201 and the second capsule portion 202 share), the first capsule portion The bulge of bulge and the second capsule portion.First capsule portion 201 and the second capsule portion 202 and the connection of distal ports outer tube can also use Mode provided by the first specific embodiment, for example, can be welded, be melted by adhesive bonding, interference fit, sound wave, Closely noose, the modes such as be closely bonded by other connectors and be attached.
It is identical as the first specific embodiment, the distal ports of the slender member 100 of the device in the specific embodiment 130 also carry marker 240.Marker 240 is also ring-type, is socketed on the outer wall of distal ports outer tube 131.In the specific implementation In mode, marker 240 is all located at the outside in capsule 200 (including the first capsule portion 201 and the second capsule portion 202) there are three having altogether, In two markers 240 be close to capsules 200 proximally and distally, another marker 240 is located at the first capsule portion 201 and the second capsule The middle position in portion 202 can clearly illustrate the position in the first capsule portion 201 and the second capsule portion 202 under ray in this way.
Fig. 8 shows the third for endovascular medical device provided by the utility model and is preferably embodied Mode.
In the specific embodiment for the thin of endovascular medical device and the first preferred embodiment The structure of long component 100 and handle 300 is identical, primary difference is that the structure of capsule 200.
In this specific embodiment, equally also there are two types of shapes for tool for capsule 200, that is, are in the first shape of contraction state (not shown) and the second shape (Fig. 8) in swelling state, similarly, when capsule 200 is in first shape, elongated structure Part 100 and capsule 200 are suitble to move in the blood vessels as a whole;When capsule 200 is in the second shape, capsule 200 plays closure blood vessel Effect.
With the first specific embodiment the difference is that in this specific embodiment, capsule 200 has tight with vascular wall Paste and block the first closure outer surface 231 of blood vessel, the second closure outer surface for being close to and blocking blood vessel with vascular wall 232 and third for being close to and blocking blood vessel with vascular wall block outer surface 233.First blocks outer surface 231, second It blocks outer surface 232 and third blocks outer surface 233 and is separated from each other in position, that is to say, that first blocks 231 He of outer surface There is the 4th chamber first to divide chamber 541, second blocks outer surface between second closure outer surface 232 and the blood vessel 400 being close to Between 232 and third closure outer surface 233 and the blood vessel 400 being close to there is the 4th chamber second to divide chamber 542.It is shown in Fig. 8 The generally calabash bunch shape of capsule 200, so-called " calabash bunch shape " refer to be, from the appearance, the main body of capsule 200 has multiple spheres The part of (three or more) or approximate spheres.
Relative to the first specific embodiment, three are utilized for endovascular medical device in the specific embodiment Separated position blocks blood vessel in position at place, and benefit is can further to mitigate the compressing and thorn to blood vessel Swash, to reduce the generation of complication.
The application utility model people it was unexpectedly observed that for typically be about 6mm vessel diameter, when capsule 200 expand To outer diameter be 7mm when, if configuring 10-21mm for the length of capsule 200 can be realized ideal plugging effect.At this moment, first Block outer surface 231, second block outer surface 232, second block one area in outer surface 233 be about 80~ 150mm2.The utility model people of the application is it has furthermore been found that the blood vessel bigger for internal diameter, for example, when capsule 200 is expanded into outer diameter When for 9mm, if configuring 10-24mm for the length of capsule 200, ideal plugging effect can be realized;Outside capsule 200 is expanded into When diameter is 10mm, if configuring 10-27mm for the length of capsule 200, ideal plugging effect can be realized.
In this specific embodiment, the material and manufacturing method of capsule 200, and the connection method with slender member 100, It is all similar with the first specific embodiment.Similarly, which further includes marker 240, and marker 240 is ring-type, quantity It is 2, is socketed on the outer wall of distal ports outer tube 131, is close to capsule 200 proximally and distally respectively.
Can be obvious, according to principle provided by the utility model, as the deformation of the specific embodiment, including three envelopes The capsule 200 of stifled outer surface is also possible to be similar to the configuration that second of specific embodiment provides, i.e. capsule 200 divides for the first capsule Portion, the second capsule portion, third capsule portion are respectively provided with mutually independent third chamber first and chamber, third chamber second are divided to divide chamber, third chamber Three points of chambers.Those skilled in the art can carry out configuration appropriate according to principle provided by the utility model, and this will not be detailed here.
Fig. 9 shows the 4th kind for endovascular medical device provided by the utility model and is preferably embodied Mode.
In the specific embodiment for the thin of endovascular medical device and the first preferred embodiment The structure of long component 100 and handle 300 is identical, primary difference is that the structure of marker 240 and position.
In this specific embodiment, marker 240 is developing material (such as barium salt (BaSO4), bismuth salt of strip (BiOCl etc.) etc.), it is embedded into inside the cyst wall of capsule 200.When capsule 200 expands, marker 240 and then expands together.It is such Mark mode is obviously more advantageous to position and the swelling state that operator observes capsule 200.
It will be apparent that the device provided in above-mentioned second of specific embodiment can also be deformed in this way, i.e., Developing material is embedded into inside the cyst wall of capsule 200, this will not be detailed here.
The preferred embodiments of the present invention have been described in detail above.It should be appreciated that this field ordinary skill without It needs creative work according to the present utility model can conceive and makes many modifications and variations.Therefore, it is all in the art Technical staff passes through logical analysis, reasoning, or a limited experiment according to the design of the utility model on the basis of existing technology can It, all should be within the scope of protection determined by the claims with obtained technical solution.

Claims (23)

1. one kind is used for endovascular medical device, including slender member, the slender member include distal ports, and described is used for Endovascular medical device further includes the expandable capsule carried by the distal ports, and the capsule at least has in contraction state First shape and the second shape in swelling state, which is characterized in that described is matched for endovascular medical device It is set to, when the capsule is in the second shape, the capsule at least has the first envelope for being close to and blocking blood vessel with vascular wall Block up outer surface and the second closure outer surface for being close to and blocking blood vessel with vascular wall;Described first blocks outer surface and second Outer surface is blocked to be separated from each other in position.
2. being used for endovascular medical device as described in claim 1, which is characterized in that described is used for endovascular medical treatment Device is balloon guide catheter.
3. being used for endovascular medical device as described in claim 1, which is characterized in that when the capsule is in the second shape When, the shape of the capsule is Pear-Shaped.
4. as described in claim 1 be used for endovascular medical device, which is characterized in that the capsule is configured as, by When the bulbs of pressure, the expansion amplitude that the first of the capsule blocks the part between outer surface and the second closure outer surface is less than described The first of capsule blocks the expansion amplitude of the part of outer surface and the part of the second closure outer surface.
5. being used for endovascular medical device as described in claim 1, which is characterized in that described is used for endovascular medical treatment Device is configured to: when it is 7mm that the capsule, which is expanded into outer diameter, the length of the capsule is not more than 14mm.
6. being used for endovascular medical device as described in claim 1, which is characterized in that described is used for endovascular medical treatment Device is configured to: when it is 9mm that the capsule, which is expanded into outer diameter, the length of the capsule is not more than 16mm.
7. being used for endovascular medical device as described in claim 1, which is characterized in that described is used for endovascular medical treatment Device is configured to: when it is 10mm that the capsule, which is expanded into outer diameter, the length of the capsule is not more than 18mm.
8. being used for endovascular medical device as described in claim 1, which is characterized in that the slender member further includes centre The first chamber and the second chamber that there is the axis for prolonging the slender member to extend for section, the distal ports and the interlude.
9. being used for endovascular medical device as claimed in claim 8, which is characterized in that the distal ports include outside distal ports Pipe and distal ports inner tube, the interlude includes interlude outer tube and interlude inner tube;First chamber includes the distal ports The inner cavity of inner tube and the inner cavity of interlude inner tube, second chamber include outside the outer wall and the distal ports of the distal ports inner tube The space between the outer wall in space and the interlude inner tube and the inner wall of the interlude outer tube between the inner wall of pipe.
10. being used for endovascular medical device as claimed in claim 9, which is characterized in that the slender member further includes close Section is held, the proximal segment includes proximal segment outer tube and proximal segment inner tube;First chamber includes the inner cavity of the proximal segment inner tube, Second chamber includes the space between the outer wall of the proximal segment inner tube and the inner wall of the proximal segment outer tube;Described is used for Endovascular medical device further includes the handle connecting with the proximal segment.
11. being used for endovascular medical device as claimed in claim 9, which is characterized in that when the capsule is in the second shape When, there is third chamber between the outer wall and the capsule of the distal ports outer tube, the distal ports outer tube has one or more holes, The third chamber is connected to by the hole with second chamber.
12. being used for endovascular medical device as claimed in claim 11, which is characterized in that when the capsule is in the second shape When, there is the 4th chamber between the outer surface and blood vessel of the capsule.
13. as claimed in claim 11 be used for endovascular medical device, which is characterized in that the capsule include the first capsule portion and Second capsule portion, first closure outer surface are located at first capsule portion, and second closure outer surface is located at second capsule Portion;Described is configured to for endovascular medical device, when the capsule is in the second shape, first capsule portion and institute Stating between the outer wall of slender member, there is third chamber first to divide chamber, have between second capsule portion and the outer wall of the slender member There is third chamber second to divide chamber;The slender member has one or more holes, the third chamber first divide chamber by the hole with The second chamber connection, the third chamber second divide chamber to be connected to by the other hole with second chamber;The third chamber First point of chamber and third chamber second divide chamber mutually indepedent.
14. being used for endovascular medical device as claimed in claim 13, which is characterized in that first capsule portion and the second capsule Portion is manufactured separately, and is individually connected to the outer wall of the distal ports outer tube.
15. being used for endovascular medical device as claimed in claim 13, which is characterized in that first capsule portion and the second capsule Portion is manufactured into one, and is coupled together to the outer wall of the distal ports outer tube.
16. being used for endovascular medical device as described in claim 1, which is characterized in that described is used for endovascular doctor Treating device further includes the marker that can be shown under ray, proximal end and/or distal end close or that be close to the capsule.
17. being used for endovascular medical device as claimed in claim 16, which is characterized in that the marker is ring-type, set It connects in the outside of the slender member.
18. being used for endovascular medical device as described in claim 1, which is characterized in that described is used for endovascular doctor Treating device further includes the marker that can be shown under ray, and the marker is the developing material being embedded in the cyst wall of the capsule.
19. being used for endovascular medical device as described in claim 1, which is characterized in that the capsule, which also has, to be used for and blood Tube wall is close to and blocks the third closure outer surface of blood vessel, and described first blocks outer surface, the second closure outer surface and third envelope Stifled outer surface is separated from each other in position.
20. being used for endovascular medical device as described in claim 1, which is characterized in that when the capsule is in the second shape When, the shape of the capsule is calabash bunch shape.
21. being used for endovascular medical device as described in claim 1, which is characterized in that described is used for endovascular doctor Treat device to be configured to: when it is 7mm that the capsule, which is expanded into outer diameter, the length of the capsule is not more than 21mm.
22. being used for endovascular medical device as described in claim 1, which is characterized in that described is used for endovascular doctor Treat device to be configured to: when it is 9mm that the capsule, which is expanded into outer diameter, the length of the capsule is not more than 24mm.
23. being used for endovascular medical device as described in claim 1, which is characterized in that described is used for endovascular doctor Treat device to be configured to: when it is 10mm that the capsule, which is expanded into outer diameter, the length of the capsule is not more than 27mm.
CN201820009031.7U 2018-01-03 2018-01-03 For endovascular medical device Active CN208582459U (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108013912A (en) * 2018-01-03 2018-05-11 上海心玮医疗科技有限公司 For endovascular medical treatment device

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108013912A (en) * 2018-01-03 2018-05-11 上海心玮医疗科技有限公司 For endovascular medical treatment device

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