CN208464335U - The mouse fixing of irradiation experiment is radiated applied to mouse leg - Google Patents
The mouse fixing of irradiation experiment is radiated applied to mouse leg Download PDFInfo
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- CN208464335U CN208464335U CN201721763889.4U CN201721763889U CN208464335U CN 208464335 U CN208464335 U CN 208464335U CN 201721763889 U CN201721763889 U CN 201721763889U CN 208464335 U CN208464335 U CN 208464335U
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- mouse
- fixing pipe
- leg
- fixing
- irradiation experiment
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Abstract
The utility model discloses a kind of mouse fixings that irradiation experiment is radiated applied to mouse leg, it includes entering fixing pipe therein for toy, it respectively can be along the baffle head and guard rails at the both ends for being axially movably arranged at fixing pipe of fixing pipe, leg fixed structure in fixing pipe is set, the leg fixed structure includes the penetrating region for being provided in fixing pipe and stretching out from fixing pipe for toy leg, it is movably disposed in fixing pipe and a part in penetrating region is made to be blocked, the slide damper that another part is exposed, the card slot for being provided in fixing pipe and being connected with penetrating region, the adjustable fixing bolt being connected on the outer wall of fixing pipe, adjustable fixing bolt and card slot cooperation are fixed on toy leg in card slot.The utility model is fixed after capable of stretching toy four limbs, and the flat orientation where adjustable toy, convenient for operation, when being suitable for studying radiation-induced skin injury, the requirement to the local irradiation of mouse leg.
Description
Technical field
The utility model relates to mouse fixed networks, radiate irradiation experiment applied to mouse leg more particularly to a kind of
Mouse fixing.
Background technique
Currently, zoopery has been widely used in biomedicine field research, to probe into internal metabolic pathway, new drug development
Data and theoretical basis abundant are provided with the innovation of art formula.People explore life by the research to animal biological phenomena itself
The secret of life, and then push away and use mankind itself, deepen the understanding to various vital movements and pathophysiological process, and finally cause
Power is in extension human longevity and improves life quality.
In radiobiology research process, radiation or pre- is often determined by parameters variation after detection mouse irradiation
Handle the biological effect generated.Wherein, in probing into skin injury effect caused by irradiation, frequently with to mouse leg skin
Carry out local irradiation method come avoid full-body exposure cause important organ damage after, mouse is dead rapidly.Existing fixation side
Mouse is limited in a certain container by formula, however mouse rolls up posture and movement seriously limits the need of leg local irradiation
It asks.Fixation is another common settling mode after anesthesia, but on the one hand often because caused by the fault of dosage and operation mouse it is unexpected
It is dead;On the other hand, anesthesia can not also estimate exclusion to the unknown influence that mouse generates.Meanwhile it can not be adjusted with upper type small
The angle orientation of mouse is not easy to irradiation and operation.
Utility model content
The purpose of this utility model is that propose a kind of mouse fixing that irradiation experiment is radiated applied to mouse leg,
Very firm fixation can be carried out to the leg of toy in irradiation experiment.
In order to achieve the above object, the utility model provides a kind of technical solution: being applied to the radiation irradiation of mouse leg
The mouse fixing of experiment, it includes can be along the axial movement of fixing pipe into fixing pipe therein, difference for toy
The baffle head and guard rails, the leg fixed structure that is arranged in fixing pipe at the both ends of fixing pipe, the leg is arranged in ground
Portion's fixed structure include be provided in fixing pipe and stretched out from fixing pipe for toy leg penetrating region, movably set
It sets in fixing pipe and makes a part in penetrating region is blocked, another part is exposed slide damper, be provided with fixing pipe
Upper and the card slot being connected with penetrating region, the adjustable fixing bolt being connected on the outer wall of fixing pipe, adjustable fixation
Bolt is matched with card slot is fixed on toy leg in card slot.
Further, slide damper is moved by itself and adjusts the area that penetrating region is exposed to block penetrating region
Size.
Further, adjustable fixing bolt is telescopic rod, and telescopic direction is the axial direction along fixing pipe.
Further, adjustable fixing bolt is rotatably connected on the outer wall of fixing pipe, and pivot center is perpendicular to fixing pipe
Axial direction.
Further, baffle head is taper.
Further, the gap therefrom stretched out for toy tail portion is offered on guard rails.
Further, restricted its position lock is respectively set between baffle head, guard rails, slide damper and fixing pipe
Determine structure.
Further, pedestal is provided on the outer wall of fixing pipe.
Further, it further includes station, which includes support frame, is pivotally connected rotation on the support frame
Platform, the branch gripping arm for being connected to turntable two sides, the connection ring for being connected in branch gripping arm and being used to be connected and fixed pipe, connection ring are located at
The top of turntable.
Further, connection ring is socketed in the outside of fixing pipe.
By using above-mentioned technical proposal, the utility model is applied to the fixed dress of mouse of mouse leg radiation irradiation experiment
It sets, it is fixed after toy four limbs capable of being stretched, and the flat orientation where adjustable toy, convenient for operation.Not only solve
In irradiation experiment, traditional mouse fixing, which can not stretch mouse, to be fixed, and is only capable of for mouse being limited to a certain region and is carried out
Full-body exposure causes the drawbacks of important device dirty damage, it is thus also avoided that the unexpected death of mouse caused by anesthesia and uncertain factor
It introduces, when this fixation device is suitable for studying radiation-induced skin injury, the requirement to the local irradiation of mouse leg, meanwhile,
This fixation device is but also widely used for the inoculation of mouse four limbs position knurl, drug is smeared and a variety of operations such as sample of tissue.
The above description is merely an outline of the technical solution of the present invention, in order to better understand the skill of the utility model
Art means, and can be implemented in accordance with the contents of the specification, below on the preferred embodiment of the present invention and the accompanying drawings in detail
It describes in detail bright as after.
Detailed description of the invention
Attached drawing 1 is to be applied in the mouse fixing of mouse leg radiation irradiation experiment in the utility model embodiment one
The overlooking structure diagram of fixation kit;
Attached drawing 2 is to be applied in the mouse fixing of mouse leg radiation irradiation experiment in the utility model embodiment one
The positive structure diagram of fixation kit;
Attached drawing 3 is to be applied in the mouse fixing of mouse leg radiation irradiation experiment in the utility model embodiment one
The side structure schematic view of fixation kit;
Attached drawing 4 is to be applied in the mouse fixing of mouse leg radiation irradiation experiment in the utility model embodiment one
The positive structure diagram of station;
Attached drawing 5 is to be applied in the mouse fixing of mouse leg radiation irradiation experiment in the utility model embodiment one
The overlooking structure diagram of station;
Attached drawing 6 is to be applied in the mouse fixing of mouse leg radiation irradiation experiment in the utility model embodiment one
The side structure schematic view of station;
Attached drawing 7 is to be applied in the mouse fixing of mouse leg radiation irradiation experiment in the utility model embodiment two
The positive structure diagram of fixation kit.
Figure label are as follows:
1, fixing pipe;2, baffle head;3, guard rails;4, slide damper;5, penetrating region;6, fixing bolt;7, pedestal;
8, screw-threaded coupling knob;9, support frame;10, turntable;11, branch gripping arm;12, connection ring;13, card slot;14, gap.
Specific embodiment
With reference to the accompanying drawings and examples, specific embodiment of the present utility model is described in further detail.Below
Embodiment is not intended to limit the scope of the present invention for illustrating the utility model.
Embodiment one
The fixed dress of mouse for being applied to the radiation irradiation experiment of mouse leg referring to attached drawing 1 to attached drawing 6, in the present embodiment
It sets, it includes fixation kit and station.
Fixation kit include for toy enter fixing pipe 1 therein, respectively can axially movably setting along fixing pipe 1
Set baffle head 2 and guard rails 3 at the both ends of fixing pipe 1, the leg fixed structure that is arranged in fixing pipe 1.
Fixing pipe 1 is cylindrical, and toy can entirely pierce wherein.
Baffle head 2 is taper, can preferably fix the head of toy.
The gap 14 therefrom stretched out for toy tail portion is offered on guard rails 3, convenient for the behaviour such as tail vein injection, blood sampling
Make.
Leg fixed structure includes the penetrating area for being provided in fixing pipe 1 and stretching out from fixing pipe 1 for toy leg
Domain 5 is movably disposed in fixing pipe 1 and keeps off the sliding that a part in penetrating region 5 is blocked, another part is exposed
Plate 4, is connected to being adjusted on the outer wall of fixing pipe 1 at the card slot 13 for being provided in fixing pipe 1 and being connected with penetrating region 5
Formula fixing bolt 6.Slide damper 4 moves that adjust the area that penetrating region 5 is exposed big to block penetrating region 5 by itself
It is small.Adjustable fixing bolt 6 is matched with card slot is fixed on toy leg in card slot 13.
In a kind of highly preferred embodiment, above-mentioned leg fixed structure at least there are two, and along fixing pipe 1
Axial arranging.Two leg fixed structures are symmetrical arranged about one perpendicular to the axial plane of fixing pipe 1.Each leg fixed knot
Structure includes two card slots 13, and two card slots 13 are separately positioned on the left and right sides in penetrating region 5.Fixing bolt 6 and 13 numbers of card slot
It is corresponding.
Adjustable fixing bolt 6 in the present embodiment is telescopic rod, and telescopic direction is the axial direction along fixing pipe 1.
In a kind of highly preferred embodiment, between baffle head 2, guard rails 3, slide damper 4 and fixing pipe 1
Its restricted position locking structure is respectively set.In the present embodiment, the position locking structure at three is screw-threaded coupling knob 8.
In a kind of highly preferred embodiment, it is provided with pedestal 7 on the outer wall of fixing pipe 1, makes fixation kit can be with
It is used alone independently of station.
Station includes support frame 9, the turntable being pivotably attached on support frame 9 10, is connected to 10 two sides of turntable
Branch gripping arm 11, the connection ring 12 for being connected in branch gripping arm 11 and being used to be connected and fixed pipe 1, connection ring 12 are located at the upper of turntable 10
Side.Connection ring 12 is separatably socketed in the outside of fixing pipe 1.10 shaft of turntable is vertically arranged.
The present embodiment introduces the working principle of this fixation device by taking mouse as an example:
1. after mouse enters fixing pipe 1 first under induction, adjusting baffle head 2 and guard rails 3 for mouse in fixation
Suitable position is fixed on 1 long axis direction of pipe;
It 2. adjusting the slide damper 4 of bottom in appropriate location, stretch out mouse thigh can in the penetrating region 5 of bottom and small
Mouse will not drill out due to the penetrating region 5 is excessive;
3. mouse thigh is pulled to export-oriented side direction under artificial traction, by mouse thigh root as being fixed on
In the card slot 13 being connected with penetrating region 5;
4. can only accommodate mouse itself since 1 caliber of fixing pipe is small, mouse huckle is only capable of below 13 indentation, there of card slot
It slips, and is not directly set back in fixing pipe 1, fixing bolt 6 is slipped downwards by limitation mouse thigh and plays fixed function.
Embodiment two
The mouse fixing for being applied to the radiation irradiation experiment of mouse leg and implementation referring to attached drawing 7, in the present embodiment
The difference of example one is only that: adjustable fixing bolt 6 is rotatably connected on the outer wall of fixing pipe 1, and pivot center is perpendicular to fixation
The axial direction of pipe 1.Fixing bolt 6 can rotate upwardly and downwardly.
Working principle:
1. to 3. with embodiment one;
4. mouse huckle is pulled into after side wall card slot 13, fixing bolt 6 is rotated, mouse thigh root is made
It is accommodated between fixing bolt 6 and the wall of card slot 13, thus plays fixed function.
Above are merely preferred embodiments of the utility model, it is not intended to limit the utility model, it is noted that for
For those skilled in the art, without deviating from the technical principle of the utility model, if can also make
Dry improvement and modification, these improvements and modifications also should be regarded as the protection scope of the utility model.
Claims (10)
1. being applied to the mouse fixing of mouse leg radiation irradiation experiment, it is characterised in that: it includes entering for toy
Fixing pipe therein, respectively can along the both ends for being axially movably arranged at fixing pipe of the fixing pipe baffle head and
Guard rails, the leg fixed structure being arranged in the fixing pipe, the leg fixed structure include being provided with the fixing pipe
It is upper and for toy leg from the penetrating region stretched out in fixing pipe, be movably disposed in the fixing pipe and make described logical
The a part in saturating region is blocked, the slide damper that another part is exposed, be provided in fixing pipe and with the penetrating region
The card slot being connected, the adjustable fixing bolt being connected on the outer wall of the fixing pipe, the adjustable fixing bolt with
The card slot, which matches, is fixed on toy leg in card slot.
2. the mouse fixing according to claim 1 applied to the radiation irradiation experiment of mouse leg, it is characterised in that:
The slide damper is moved by itself and adjusts the size exposed in penetrating region to block the penetrating region.
3. the mouse fixing according to claim 1 applied to the radiation irradiation experiment of mouse leg, it is characterised in that:
The adjustable fixing bolt is telescopic rod, and telescopic direction is the axial direction along fixing pipe.
4. the mouse fixing according to claim 1 applied to the radiation irradiation experiment of mouse leg, it is characterised in that:
The adjustable fixing bolt is rotatably connected on the outer wall of fixing pipe, axial direction of the pivot center perpendicular to fixing pipe.
5. the mouse fixing according to claim 1 applied to the radiation irradiation experiment of mouse leg, it is characterised in that:
The baffle head is taper.
6. the mouse fixing according to claim 1 applied to the radiation irradiation experiment of mouse leg, it is characterised in that:
The gap therefrom stretched out for toy tail portion is offered on the guard rails.
7. the mouse fixing according to claim 1 applied to the radiation irradiation experiment of mouse leg, it is characterised in that:
Its restricted position locking structure is respectively set between the baffle head, guard rails, slide damper and fixing pipe.
8. the mouse fixing according to claim 1 applied to the radiation irradiation experiment of mouse leg, it is characterised in that:
Pedestal is provided on the outer wall of the fixing pipe.
9. the mouse fixing according to claim 1 applied to the radiation irradiation experiment of mouse leg, it is characterised in that:
It further includes station, which includes support frame, the turntable being pivotably attached on support frame as described above, is connected to the rotation
The branch gripping arm of turntable two sides, the connection ring for being connected in the branch gripping arm and being used to connect the fixing pipe, the connection ring position
In the top of turntable.
10. the mouse fixing according to claim 9 applied to the radiation irradiation experiment of mouse leg, feature exist
In: the connection ring is socketed in the outside of the fixing pipe.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN201721763889.4U CN208464335U (en) | 2017-12-15 | 2017-12-15 | The mouse fixing of irradiation experiment is radiated applied to mouse leg |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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CN201721763889.4U CN208464335U (en) | 2017-12-15 | 2017-12-15 | The mouse fixing of irradiation experiment is radiated applied to mouse leg |
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CN208464335U true CN208464335U (en) | 2019-02-05 |
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CN201721763889.4U Active CN208464335U (en) | 2017-12-15 | 2017-12-15 | The mouse fixing of irradiation experiment is radiated applied to mouse leg |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110353720A (en) * | 2019-08-29 | 2019-10-22 | 中南大学湘雅医院 | Synchrotron radiation X-ray Micro-CT scanning and fixed device suitable for toy four limbs living imaging |
CN112603578A (en) * | 2020-12-21 | 2021-04-06 | 杭州市第一人民医院 | Murine radiation fixing device |
-
2017
- 2017-12-15 CN CN201721763889.4U patent/CN208464335U/en active Active
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110353720A (en) * | 2019-08-29 | 2019-10-22 | 中南大学湘雅医院 | Synchrotron radiation X-ray Micro-CT scanning and fixed device suitable for toy four limbs living imaging |
CN112603578A (en) * | 2020-12-21 | 2021-04-06 | 杭州市第一人民医院 | Murine radiation fixing device |
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