CN208446473U - It is a kind of to automate filling cell cryopreservation bag on a large scale suitable for machine - Google Patents
It is a kind of to automate filling cell cryopreservation bag on a large scale suitable for machine Download PDFInfo
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- CN208446473U CN208446473U CN201821048006.6U CN201821048006U CN208446473U CN 208446473 U CN208446473 U CN 208446473U CN 201821048006 U CN201821048006 U CN 201821048006U CN 208446473 U CN208446473 U CN 208446473U
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- cryopreservation bag
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Abstract
The utility model discloses a kind of to automate filling cell cryopreservation bag suitable for machine on a large scale, including cell cryopreservation bag bag body, butterfly clamp connector and connection hose is respectively set on the both sides of rectangular cell cryopreservation bag bag body apical lateral, it connects the hose other end and connects sample funnel, sample funnel top is added with isolating cap, outer wall setting in sample funnel lower part cooperates the Machine automated filling locating piece used, and cell cryopreservation bag bag body Basolateral is provided with label bag, printing lot number region and infusion bag hanging hole.There is the heat seal folding region that can be folded in the label bag of the cell cryopreservation bag bag body and bottom end side, printing lot number region between infusion bag hanging hole.Cell cryopreservation bag can be placed in liquid nitrogen and freeze, and after defrosting, cell cryopreservation bag is hung on infusion support, can avoid cell that can remain freezing bag as far as possible, promote cell drug large scale preparation.
Description
Technical field
It is specially a kind of to automate filling cell jelly on a large scale suitable for machine the utility model relates to cell cryopreservation bag
Deposit bag.
Background technique
Stem-cell research and the development of regenerative medicine are the traumatic of facing mankind, immunity, metabolic, degeneration and swell
The intractable therapy of serious disease such as tumor will provide revolutionary solution.By in March, 2018, U.S.'s NIH clinical research
The global registration stem cell relevant clinical of website registration is tested more than 6504, I phase, II phase, III phase, IV phase clinical research point
It Wei not be 2185,3147,652 and 183.Wherein, candidate stem cell (HSC) studies 2293 and accounts for 35%；Mesenchyma is dry
Cell (MSC) studies 807 and accounts for 12%, and relating generally to disease type includes apoplexy, sarcoidosis of lung, peripheral arterial disease, class wind
Wet arthritis, idiopathic pulmonary fibrosis and immunological diseases etc.；Embryonic stem cell (ES)/inductive pluripotent stem cells (iPSC)
It is 2% that research 115, which accounts for, is concentrated mainly on eyes, pancreas and a variety of neurodegenerative diseases or damage (such as parkinsonism, ALS
And spinal cord injury) therapy field；Neural stem cell research (NSC) 55 accounts for 1%, is primarily intended to repair impaired nervous centralis
System.
The shared nearly 300 kinds of stem cell related drugs in the whole world are being researched and developed at present, so far the U.S., Canada, European Union, Korea Spro
The drug regulatory department of the countries and regions such as state, Japan, India, New Zealand has been approved by 17 stem cell preparations listings.
2 months 2016,(i.e.) stem cell preparations are anti-for treating graft in Japanese list marketing
Host disease becomes the stem cell products of the first large-scale production ratified completely.Common cell cryopreservation bag is not applicable at present
In the extensive filling cell cryopreservation bag of machine, exploitation one is suitable for automating extensive filling cell cryopreservation bag gesture must
Row.
Utility model content
It is unsuitable for extensive filling to solve cell cryopreservation bag of the existing technology, the utility model provides a kind of be applicable in
Automate filling cell cryopreservation bag on a large scale in machine.
In order to solve the above-mentioned technical problem, the utility model provides the following technical solution: it is big that one kind being suitable for machine
Scale automates filling cell cryopreservation bag, including cell cryopreservation bag bag body, outside rectangular cell cryopreservation bag bag body top
Butterfly clamp connector and connection hose is respectively set in the both sides of side, and the connection hose other end connects sample funnel, sample funnel top
End cooperates the Machine automated filling locating piece used, cell cryopreservation bag bag added with isolating cap, the setting of sample funnel lower part outer wall
Body Basolateral is provided with label bag, prints lot number region and infusion bag hanging hole.
The label bag of the cell cryopreservation bag bag body and bottom end side, printing lot number region, have between infusion bag hanging hole can be with
The heat seal folding region of folding.
The printing lot number region is for imprinting lot number and product brand.
On the inside of the bag body of the lateral surface of the cell cryopreservation bag bag body top inner side butterfly clamp connector and connection hose
There is an oblique angle flanging, avoid the occurrence of dead angle, causes cell residue in cell cryopreservation bag bag body.
The cell cryopreservation bag is all made of ethylene-vinyl acetate copolymer EVA in addition to sample funnel and is made.
The locating piece is that two circle tools integrally formed with sample funnel and protrusion sample funnel outer wall are at regular intervals
Protruding ring.
Compared with prior art, the utility model has the following beneficial effects: automatic filling machine device can be cooperated to use,
It can also can be placed in liquid nitrogen and freeze with manual filling, after defrosting, cell cryopreservation bag is hung on infusion support, can be kept away as far as possible
Exempting from cell can remain freezing bag.
Detailed description of the invention
Fig. 1 is the overall structure signal that the utility model is suitable for that machine automates filling cell cryopreservation bag on a large scale
Figure；
Fig. 2 is the sample funnel of the utility model and the perspective view of isolating cap.
Fig. 3 is the sectional view of the sample funnel of the utility model.
In figure: 1, cell cryopreservation bag bag body, 2, butterfly clamp connector, 3, label bag, 4, printing lot number region, 5, infusion bag
Hanging hole, 6, sample funnel, 7, locating piece, 8, connection hose, 9, isolating cap, 10, heat seal folding region, 11, protruding ring.
Specific embodiment
To be easy to understand the technical means, creative features, achievement of purpose, and effectiveness of the utility model, below
In conjunction with specific embodiment, the utility model is further described.
As shown in Figure 1-3, the machine that is suitable for of the utility model automates filling cell cryopreservation bag on a large scale, including thin
Born of the same parents freeze bag bag body 1, and 2 He of butterfly clamp connector is respectively set on the both sides of rectangular 1 apical lateral of cell cryopreservation bag bag body
Hose 8 is connected, the connection hose other end connects sample funnel 6, and 6 top of sample funnel is added with isolating cap 9,6 lower part of sample funnel
Outer wall setting cooperates the Machine automated filling locating piece 7 used, 1 Basolateral of cell cryopreservation bag bag body be provided with label bag 3,
Print lot number region 4 and infusion bag hanging hole 5.
The label bag 3 of the cell cryopreservation bag bag body 1 and bottom end side, printing lot number region 4 have between infusion bag hanging hole 5
The heat seal folding region 10 that can be folded.
The printing lot number region 4 is for imprinting lot number and product brand.
On the inside of the bag body of the lateral surface of the 1 top inner side butterfly clamp connector of cell cryopreservation bag bag body and connection hose
There is an oblique angle flanging, avoid the occurrence of dead angle, causes cell residue in cell cryopreservation bag bag body.
The cell cryopreservation bag is all made of ethylene-vinyl acetate copolymer EVA in addition to sample funnel 6 and is made.
The locating piece 7 is that two circle tools integrally formed with sample funnel 6 and protrusion 6 outer wall of sample funnel are at regular intervals
Protruding ring 11.
The cell cryopreservation bag can freeze in liquid nitrogen.
When specifically used, when storing cell, the cell for first completing preparation opens isolation by machine or manual filling
Cap 9 enters bag body by connection hose 8, connects the nearly bag body end of hose 8 by heat seal instrument heat seal, cut off heat from sample funnel 6
Close 6 side of sample funnel at position.It is put into the label of the lot number product in label bag 3, folds heat seal folding region 10.Cell is frozen
It deposits bag and is put into and freeze in protecting box, after cooling down by program, be transferred to liquid nitrogen cryopreservation.It is filling set that locating piece 7 is easy for machine
It sets, printing lot number region 4 can print the product batch number of cell cryopreservation and freeze a bag trade mark.Cell is wanted in use, from liquid nitrogen container
Middle taking-up cell cryopreservation bag, thaws in 37-40 DEG C of water-bath, then unscrews butterfly clamp connector 2, can be with syringe toward even
A certain amount of sterile electrolyte injection is injected in interface 2, is inserted into blood transfusion apparatus, and infusion support is hung over by infusion bag hanging hole 5,
Carry out cell infusion.After can also thawing, butterfly clamp connector 2 is unscrewed, blood transfusion apparatus is inserted into, hung by infusion bag hanging hole 5
In infusion support, cell infusion is carried out.
The basic principles and main features of the present invention and the advantages of the present invention have been shown and described above.Current row
The technical staff of industry is described in above embodiments and description it should be appreciated that the present utility model is not limited to the above embodiments
Only illustrate the principles of the present invention, on the premise of not departing from the spirit and scope of the utility model, the utility model is also
It will have various changes and improvements, these various changes and improvements fall within the scope of the claimed invention.The utility model
Claimed range is defined by the appending claims and its equivalent thereof.
Claims (6)
1. a kind of automate filling cell cryopreservation bag, including cell cryopreservation bag bag body (1), feature suitable for machine on a large scale
It is, butterfly clamp connector (2) is respectively set on the both sides of rectangular cell cryopreservation bag bag body (1) apical lateral and connection is soft
It manages (8), connection hose other end connection sample funnel (6), sample funnel (6) top is added with isolating cap (9), sample funnel (6)
Outer wall setting in lower part cooperates the Machine automated filling locating piece (7) used, and cell cryopreservation bag bag body (1) Basolateral is provided with
Label bag (3), printing lot number region (4) and infusion bag hanging hole (5).
2. be suitable for machine according to claim 1 automates filling cell cryopreservation bag on a large scale, which is characterized in that described
The label bag (3) of cell cryopreservation bag bag body (1) and bottom end side, printing lot number region (4), have between infusion bag hanging hole (5) can be with
The heat seal folding region (10) of folding.
3. be suitable for machine according to claim 1 automates filling cell cryopreservation bag on a large scale, which is characterized in that described
Printing lot number region (4) is for imprinting lot number and product brand.
4. be suitable for machine according to claim 1 automates filling cell cryopreservation bag on a large scale, which is characterized in that described
There is an oblique angle on the inside of the bag body of the lateral surface of cell cryopreservation bag bag body (1) top inner side butterfly clamp connector and connection hose
Flanging avoids the occurrence of dead angle, causes cell residue in cell cryopreservation bag bag body.
5. be suitable for machine according to claim 1 automates filling cell cryopreservation bag on a large scale, which is characterized in that described
Cell cryopreservation bag is all made of ethylene-vinyl acetate copolymer EVA in addition to sample funnel (6) and is made.
6. be suitable for machine according to claim 1 automates filling cell cryopreservation bag on a large scale, which is characterized in that described
Locating piece (7) is integrally formed with sample funnel (6) and protrudes the two of sample funnel (6) outer wall circle tool protrusions at regular intervals
Ring (11).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821048006.6U CN208446473U (en) | 2018-07-04 | 2018-07-04 | It is a kind of to automate filling cell cryopreservation bag on a large scale suitable for machine |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821048006.6U CN208446473U (en) | 2018-07-04 | 2018-07-04 | It is a kind of to automate filling cell cryopreservation bag on a large scale suitable for machine |
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| Publication Number | Publication Date |
|---|---|
| CN208446473U true CN208446473U (en) | 2019-02-01 |
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| CN201821048006.6U Active CN208446473U (en) | 2018-07-04 | 2018-07-04 | It is a kind of to automate filling cell cryopreservation bag on a large scale suitable for machine |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111607561A (en) * | 2020-05-14 | 2020-09-01 | 北京唐颐惠康生物医学技术有限公司 | Method for constructing large-scale, high-throughput and high-safety stem cell bank |
-
2018
- 2018-07-04 CN CN201821048006.6U patent/CN208446473U/en active Active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111607561A (en) * | 2020-05-14 | 2020-09-01 | 北京唐颐惠康生物医学技术有限公司 | Method for constructing large-scale, high-throughput and high-safety stem cell bank |
| CN111607561B (en) * | 2020-05-14 | 2023-08-11 | 北京唐颐惠康生物医学技术有限公司 | Construction method of large-scale, high-flux and high-safety stem cell library |
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