CN208390248U - A kind of centrifuge handling cell - Google Patents
A kind of centrifuge handling cell Download PDFInfo
- Publication number
- CN208390248U CN208390248U CN201820797326.5U CN201820797326U CN208390248U CN 208390248 U CN208390248 U CN 208390248U CN 201820797326 U CN201820797326 U CN 201820797326U CN 208390248 U CN208390248 U CN 208390248U
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- centrifuge
- mechanical arm
- turning joint
- mechanical
- pedestal
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Abstract
This application involves instrument equipment technology field more particularly to a kind of centrifuges for handling cell, to improve defect existing in the prior art.It include: casing, cover, operation panel, internal structure, adjustable frames and centrifuge tube and mechanical picking unit;Cover is connect by support rod with casing, and is realized by the controller on operation panel to the control of support rod and automatically turned on or close;Adjustable frames include: regulating mechanism and protection shell;Regulating mechanism includes: tubbiness pedestal and column adjusts bolt, and the inner wall of tubbiness pedestal is provided with screw thread, and links together with column adjusting bolt cooperation rotation and adjustable frames are adjusted.To avoid human contact's centrifuge tube and the pollution that may cause.Meanwhile avoiding during opening, closing, acutely lead to the problem of separated culture solution mixes again and reduces separation accuracy due to acting, and above-mentioned centrifuge can adapt to rugged use environment, promote the use scope of centrifuge.
Description
Technical field
This application involves instrument equipment technology field more particularly to a kind of centrifuges for handling cell.
Background technique
In RESEARCH ON CELL-BIOLOGY field and life science field, cell culture is most basic link.And
In cell cultivation process, centrifuge separation is the effective ways for realizing the separation of solid and liquid of cell culture, mainly by cell solution
It imports in centrifuge tube, centrifuge tube is then transferred to corresponding centrifugal separating device (generally handling the centrifuge of cell) and is carried out
Centrifugal treating;After some time, cell solution can be gathered in the bottom of centrifuge tube under the centrifugal force traction of centrifuge,
After centrifuge, supernatant in centrifuge tube and following cell can be subjected to separating treatment, obtain required cell.
However, being had the following deficiencies: when being separated to cell culture
1, it needs work one by one to put into a centrifuge centrifuge tube, and complete monitoring is carried out to separation process, and separating
After, then the culture solution after separation is taken out and is separated;As it can be seen that needing artificial participation, resource is expended;And in artificial participation process
In easily culture solution is polluted;
2, when in use, due to the limitation of environment, it is firm to be likely to result in workbench out-of-flatness for centrifuge, influences centrifuge
Efficiency;
3, the cover of existing centrifuge mostly uses electromagnetic lock, thus, it is more acute due to acting during open and close
It is strong, it easily leads to separated culture solution and mixes again, reduce separation accuracy.
Summary of the invention
The embodiment of the present application provides a kind of centrifuge for handling cell, existing in the prior art above-mentioned scarce to improve
The problem of falling into.
The embodiment of the present application adopts the following technical solutions:
A kind of centrifuge handling cell, comprising: casing, cover, operation panel, internal structure, setting are in the casing
The adjustable frames of bottom and several separable centrifuge tubes and the mechanical picking unit being fixed on casing;Wherein, institute
It states cover to connect by support rod with casing, and the control realization of the support rod is opened automatically by the controller on operation panel
It opens or closes;The adjustable frames specifically include: regulating mechanism and the protection shell for wrapping up the regulating mechanism;The adjusting
Mechanism specifically includes: tubbiness pedestal and column adjust bolt, and the inner wall of the tubbiness pedestal is provided with screw thread, and with the column
Adjusting bolt cooperation rotation, which links together, is adjusted the adjustable frames.
Optionally, mechanical picking unit includes mechanical picking unit pedestal, first mechanical arm, second mechanical arm, third machine
Tool arm, the first turning joint, the second turning joint, third turning joint, gripper, mechanical picking unit pedestal are fixed on casing
Side wall;First rotation drive device is set in mechanical picking unit pedestal, and drive shaft is vertically arranged, and driving axis connection one is hung down
The first mechanical arm being directly arranged, first mechanical arm are able to drive the rotation of other mechanical arms;First mechanical arm and second mechanical arm it
Between with the first turning joint be flexibly connected, the rotary shaft of first turning joint is parallel to horizontal plane, so that second mechanical arm
Fan shape moving is done in a perpendicular;Built-in second rotation drive device of second mechanical arm, the second rotation drive device it is defeated
Shaft is parallel to horizontal plane, for driving second mechanical arm rotation;Second mechanical arm is mechanical by the second turning joint and third
Arm is flexibly connected, and the rotary shaft of second turning joint is parallel to horizontal plane, so that third mechanical arm remains and level
Face is parallel;Third mechanical arm is connected by the ontology of third turning joint and gripper, the rotary shaft of the third turning joint
It is parallel to horizontal plane, so that the ontology of gripper is remained and is parallel to the horizontal plane;The built-in electromagnetism of the ontology of gripper acts machine
Structure, three fingers of gripper can do grasping movement under the driving of electromagnetism actuating mechanism, when grabbing centrifuge tube, three fingers
It inwardly collapses, surrounds the gripping surface substantially in cylindrical surface.
Optionally, the controller carries out signal control by single-chip microcontroller.
Optionally, further includes: the resilient cushion of the tubbiness base bottom is set.
Optionally, the resilient cushion is elastic rubber pad.
Optionally, the column adjusts and is provided with graduation mark on bolt.
Optionally, the controller controls the support rod and at the uniform velocity rises, to be supported to the cover.
Optionally, the sensor for positioning centrifuge tube position is additionally provided in the mechanical picking unit.
Optionally, further includes: the cushion in the region being bonded in the cover with the casing is set.
The embodiment of the present application use at least one above-mentioned technical solution can reach it is following the utility model has the advantages that
Through the above technical solutions, do not need manually to participate in, and avoid human contact's centrifuge tube and the pollution that may cause.
Meanwhile support rod 16 is controlled by controller 131 and is slowly risen, cover 12 is automatically turned on or closes to support cover 12 to realize,
It avoids during opening, closing, it is more violent due to acting, it easily leads to separated culture solution and mixes and reduce again
The problem of separating accuracy, improves the efficiency of separation on the whole.Above-mentioned centrifuge can adapt to rugged using ring
Border promotes the use scope of centrifuge, meanwhile, guarantee the centrifugal efficiency of centrifuge.
Detailed description of the invention
The drawings described herein are used to provide a further understanding of the present application, constitutes part of this application, this Shen
Illustrative embodiments and their description please are not constituted an undue limitation on the present application for explaining the application.In the accompanying drawings:
Fig. 1 is the structural schematic diagram of the centrifuge of processing cell provided by the embodiments of the present application;
Fig. 2 is the structural schematic diagram of adjustable frames 15;
Fig. 3 is the structural schematic diagram of regulating mechanism 18.
Description of symbols:
Casing 11, cover 12, operation panel 13, internal structure 14, adjustable frames 15, mechanical picking unit 16, mechanical gripping
Take unit pedestal 161, first mechanical arm 162a, second mechanical arm 162b, third mechanical arm 162c, turning joint 163, gripper
164, support rod 17, regulating mechanism 18, protection shell 19, resilient cushion 110, cushion 111;Controller 131, tubbiness pedestal 181,
Column adjusts bolt 182.
Specific embodiment
To keep the purposes, technical schemes and advantages of the application clearer, below in conjunction with the application specific embodiment and
Technical scheme is clearly and completely described in corresponding attached drawing.Obviously, described embodiment is only the application one
Section Example, instead of all the embodiments.Based on the embodiment in the application, those of ordinary skill in the art are not doing
Every other embodiment obtained under the premise of creative work out, shall fall in the protection scope of this application.
Centrifuge is the device using each component in the mixture of centrifugal force, separation liquid and solid particle or liquid and liquid
Tool.Centrifuge involved at present is mainly used for separating solid particle and the liquid in suspension, or by emulsion two
Different, the again immiscible liquid of kind density separates.When the suspension standing containing fine particle is motionless, due to gravitational field
Effect is so that the particle to suspend gradually sinks.Particle is heavier, sinks faster, and the small particle of density ratio liquid on the contrary will float.
The speed that particle moves under gravitational field is related with the size of particle, form and density, and with the intensity of gravitational field and liquid
The viscosity of body is related.By taking red blood cell as an example, particle diameter is micron order, can observe that red blood cell is micro- under conventional articulated gravity effect
The infall process of grain.In addition, being also accompanied by diffusion phenomena when substance settles in the medium, diffusion is unconditional, absolute, expansion
It dissipates and the quality of substance is inversely proportional, the smaller diffusion of particle is more serious.And settle be it is opposite, conditional, by external force
It can move, sedimentation is directly proportional to weight of object, and particle is bigger, and sedimentation is faster.For the particle less than several microns such as virus or albumen
Matter etc., they, can not be it is observed that infall process just with gravity in the solution at colloid or hemicolloid state.Because
The smaller sedimentation of particle is slower, and diffusion phenomena are then more serious.So needing to generate powerful centrifugal force using centrifuge, could compel
Make these particles that diffusion be overcome to generate subsiding movement.Centrifugal treating is exactly to utilize the powerful of centrifuge rotor high speed rotation generation
Centrifugal force, the sinking speed of particle in accelerating liquid separate the substance of sedimentation coefficients different in sample and buoyant density.
Below in conjunction with attached drawing, the technical scheme provided by various embodiments of the present application will be described in detail.
Shown in referring to Fig.1, for the structural schematic diagram of the centrifuge of processing cell provided by the embodiments of the present application, the centrifugation
Machine specifically includes that
Casing 11, cover 12, operation panel 13, internal structure 14, the adjustable frames 15 that 11 bottom of casing is set
And several separable centrifuge tubes and the mechanical picking unit 16 being fixedly connected on casing 11;The cover 12 passes through branch
Strut 17 is connect with casing 11, and is opened automatically by the controller 131 on operation panel 13 the control realization of the support rod 17
It opens or closes;Support rod 17 is automatically controlled support rod, is driven by motor or hydraulic-driven, can be selected from existing automatically controlled support
Bar.The principle of the automatically controlled support rod and the electric tail gate of automobile are similar.
Optionally, centrifuge tube can be separated with centrifuge, and controller 131 referred to herein is also used to control mechanical gripping
Unit 16 is taken to grab centrifuge tube, in the card slot that centrifuge tube is placed to internal structure 14, to connect and fix centrifuge tube.It is not required to as a result,
It manually to participate in, and avoid human contact's centrifuge tube and the pollution that may cause.Meanwhile support rod is controlled by controller 131
17 slowly rise, and automatically turn on or close cover 12 to support cover 12 to realize, avoid during opening, closing, due to
Movement is more violent, easily leads to the problem of separated culture solution mixes again and reduces separation accuracy, mentions on the whole
Isolated efficiency is risen.
Mechanical picking unit 16 include mechanical picking unit pedestal 161, first mechanical arm 162a, second mechanical arm 162b,
Third mechanical arm 162c, turning joint 163(include the first turning joint, the second turning joint, third turning joint), gripper
164, mechanical picking unit pedestal 161 is fixed on the side wall of casing 11, and the two engagement surface opens up harness opening, so that mechanical gripping
The control harness of unit 16 is taken to pass through.First rotation drive device is set in mechanical picking unit pedestal 161, drive shaft is vertically set
It sets, the vertically disposed first mechanical arm 162a of axis connection one, first mechanical arm 162a is driven to be able to drive the rotation of other mechanical arms,
It such as drives near 14 top of second mechanical arm 162b reaching inwards structure;Between first mechanical arm 162a and second mechanical arm 162b
It is flexibly connected with the first turning joint, the first turning joint includes swivel bearing, and rotary shaft is parallel to horizontal plane, so that the second machine
Tool arm 162b does fan shape moving in a perpendicular;Built-in second rotation drive device of second mechanical arm 162b, the second rotation
The output shaft of driving device is parallel to horizontal plane and connect with the first turning joint, for driving second mechanical arm 162b rotation;
Second mechanical arm 162b is flexibly connected by the second turning joint with third mechanical arm 162c, and the second turning joint includes rotary shaft
It holds, bearing rotary axis is parallel to horizontal plane, so that third mechanical arm 162c is remained and is parallel to the horizontal plane;Third mechanical arm
162c is connect by third turning joint with the ontology of gripper 164, and third turning joint includes swivel bearing, and rotary shaft is parallel
In horizontal plane, so that the ontology of gripper 164 is remained and is parallel to the horizontal plane, the gripping surface of gripper 164 is kept to begin with this
End and horizontal plane.Three fingers of the built-in electromagnetism actuating mechanism of the ontology of gripper 164, gripper 164 can be in electromagnetism
Grasping movement is done under the driving of actuating mechanism, when grabbing centrifuge tube, three fingers are inwardly collapsed, and surround the crawl on substantially cylindrical surface
Face.
In other embodiments, the ontology of gripper 164 can not be parallel to the horizontal plane, and at an angle, this depends on
In the placed angle of centrifuge tube, or the angle being arranged from the angle convenient for crawl.
Optionally, mechanical picking unit 16 can also can be realized other machinery of centrifuge tube crawl using existing other
Hand, mechanical arm, gripper structure.
In addition, the structural schematic diagram of adjustable frames 15 as shown in connection with fig. 2, which is specifically included: being adjusted
It saves mechanism 18 and wraps up the protection shell 19 of the regulating mechanism 18;Wherein, protection shell 19 is generally the dust-proof material of colloid, uses
To play protective action to regulating mechanism 18.The structural schematic diagram of regulating mechanism 18 as shown in connection with fig. 3, the regulating mechanism 18 tool
Body includes: that tubbiness pedestal 181 and column adjust bolt 182, and the inner wall of the tubbiness pedestal 181 is provided with screw thread, and with column tune
The section cooperation rotation of bolt 182, which links together, is adjusted the height of adjustable frames 15.To no matter guarantee the centrifuge
Where use, the mutual cooperation of bolt 182 can be adjusted by tubbiness pedestal 181 and column, each by centrifuge can
Adjustment base 15 is adjusted to required height, to adapt to rugged use environment, promotes the use scope of centrifuge, together
When, guarantee the centrifugal efficiency of centrifuge.
Optionally, in this application, controller 131 shown in FIG. 1 can by chip microcontroller, specifically receivable signal or
Signal is sent, and control of the processing realization to mechanical picking unit 16 or cover is carried out to signal.
Optionally, centrifuge shown in the embodiment of the present application, it is shown referring to Fig.1, further includes: to be arranged in tubbiness pedestal 181
The resilient cushion 110 of bottom;Wherein, the bottom of tubbiness pedestal 181 can be circle, correspondingly, be arranged in 181 bottom of tubbiness pedestal
Resilient cushion 110 shape it is matching, thickness may be provided within the scope of 2-3mm.The resilient cushion 110 is elastic rubber pad.
In fact, resilient cushion 110 can be attached to 181 bottom of tubbiness pedestal by adhesive glue, can also be arranged in 181 bottom of tubbiness pedestal
Resilient cushion 110 is limited in groove by groove, and slightly thicker, such as 5mm can be set in the thickness of resilient cushion 110 at this time
Left and right, so that the thickness of resilient cushion 110 is greater than the depth of groove.
Optionally, for the ease of precisely being adjusted to adjustable frames 15, column adjusts and is provided with scale on bolt 182
Line.
Optionally, in order to further improve vibration influence when cover 12 opens or closes, controller 131 controls the branch
17 uniform speed slow of strut rises, to be supported to cover 12.
Optionally, in this application, it is taken, put to guarantee that mechanical picking unit 16 to centrifuge tube can accurately grab
It sets, the sensor for positioning centrifuge tube position can be provided in mechanical picking unit 16.Sensor can be located at the first machine
Tool arm 162a, second mechanical arm 162b, third mechanical arm 162c, the first turning joint, the second turning joint, third activity are closed
One or more positions in section, gripper 164.
Optionally, it is contemplated that when being opened or closed to cover 12, although controlling support rod 17 by controller 131
Uniform speed slow rises, to realize the purpose for slowing down vibration influence.But still can more or less have small vibration, in order into
One step reduces or even eliminates vibration, and the region being bonded in cover 12 with the casing 11 is provided with cushion 111.
The above description is only an example of the present application, is not intended to limit this application.For those skilled in the art
For, various changes and changes are possible in this application.All any modifications made within the spirit and principles of the present application are equal
Replacement, improvement etc., should be included within the scope of the claims of this application.
Claims (8)
1. it is a kind of handle cell centrifuge, comprising: casing (11), cover (12), operation panel (13), internal structure (14),
It is arranged in the adjustable frames (15) of the casing (11) bottom and several separable centrifuge tubes and is fixed on casing
(11) the mechanical picking unit (16) on;Wherein, the cover (12) is connect by support rod (17) with casing (11), and is passed through
Controller (131) on operation panel (13), which realizes the control of the support rod (17), to automatically turn on or closes;It is described adjustable
Pedestal (15) specifically includes: the protection shell (19) of regulating mechanism (18) and the package regulating mechanism (18);The adjusting machine
Structure (18) specifically includes: tubbiness pedestal (181) and column adjust bolt (182), and the inner wall of the tubbiness pedestal (181) is provided with
Screw thread, and link together with column adjusting bolt (182) cooperation rotation and the adjustable frames (15) are adjusted;
Mechanical picking unit (16) includes mechanical picking unit pedestal, first mechanical arm, second mechanical arm, third mechanical arm, the
One turning joint, the second turning joint, third turning joint, gripper, mechanical picking unit pedestal are fixed on casing (11)
Side wall;First rotation drive device is set in mechanical picking unit pedestal, and drive shaft is vertically arranged, and driving axis connection one is vertical
The first mechanical arm of setting, first mechanical arm are able to drive the rotation of other mechanical arms;Between first mechanical arm and second mechanical arm
It is flexibly connected with the first turning joint, the rotary shaft of first turning joint is parallel to horizontal plane, so that second mechanical arm exists
Fan shape moving is done in one perpendicular;Built-in second rotation drive device of second mechanical arm, the output of the second rotation drive device
Axis is parallel to horizontal plane, for driving second mechanical arm rotation;Second mechanical arm passes through the second turning joint and third mechanical arm
It is flexibly connected, the rotary shaft of second turning joint is parallel to horizontal plane, so that third mechanical arm remains and horizontal plane
In parallel;Third mechanical arm is connected by the ontology of third turning joint and gripper, and the rotary shaft of the third turning joint is flat
Row is in horizontal plane, so that the ontology of gripper is remained and is parallel to the horizontal plane;The built-in electromagnetism actuating mechanism of the ontology of gripper,
Three fingers of gripper can do grasping movement under the driving of electromagnetism actuating mechanism, when grabbing centrifuge tube, three fingers to
Interior gathering surrounds the gripping surface substantially in cylindrical surface.
2. centrifuge as described in claim 1, which is characterized in that the controller (131) carries out signal control by single-chip microcontroller
System.
3. centrifuge as described in claim 1, which is characterized in that further include: it is arranged in tubbiness pedestal (181) bottom
Resilient cushion (110).
4. centrifuge as claimed in claim 3, which is characterized in that the resilient cushion (110) is elastic rubber pad.
5. centrifuge as described in claim 1, which is characterized in that the column adjusts and is provided with graduation mark on bolt (182).
6. centrifuge as described in claim 1, which is characterized in that it is even that the controller (131) controls the support rod (17)
Speed rises, to be supported to the cover (12).
7. centrifuge as described in claim 1, which is characterized in that be additionally provided with and be used in the machinery picking unit (16)
Position the sensor of centrifuge tube position.
8. centrifuge as described in claim 1, which is characterized in that further include: it is arranged in the cover (12) and the machine
The cushion (111) in the region of shell (11) fitting.
Priority Applications (1)
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CN201820797326.5U CN208390248U (en) | 2018-05-25 | 2018-05-25 | A kind of centrifuge handling cell |
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CN201820797326.5U CN208390248U (en) | 2018-05-25 | 2018-05-25 | A kind of centrifuge handling cell |
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CN201820797326.5U Expired - Fee Related CN208390248U (en) | 2018-05-25 | 2018-05-25 | A kind of centrifuge handling cell |
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110694804A (en) * | 2019-11-29 | 2020-01-17 | 上海百傲科技股份有限公司 | Reagent centrifugation system |
CN114377862A (en) * | 2021-11-30 | 2022-04-22 | 青岛海尔生物医疗科技有限公司 | Method and device for controlling a centrifuge, centrifuge and storage medium |
CN114484867A (en) * | 2022-01-25 | 2022-05-13 | 爱能森(深圳)高端智能装备有限公司 | Industrial waste heat type ultra-high temperature heat pump unit |
-
2018
- 2018-05-25 CN CN201820797326.5U patent/CN208390248U/en not_active Expired - Fee Related
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110694804A (en) * | 2019-11-29 | 2020-01-17 | 上海百傲科技股份有限公司 | Reagent centrifugation system |
CN114377862A (en) * | 2021-11-30 | 2022-04-22 | 青岛海尔生物医疗科技有限公司 | Method and device for controlling a centrifuge, centrifuge and storage medium |
WO2023098093A1 (en) * | 2021-11-30 | 2023-06-08 | 青岛海尔生物医疗科技有限公司 | Method and device for controlling centrifugal machine, centrifugal machine, and storage medium |
CN114484867A (en) * | 2022-01-25 | 2022-05-13 | 爱能森(深圳)高端智能装备有限公司 | Industrial waste heat type ultra-high temperature heat pump unit |
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Granted publication date: 20190118 Termination date: 20210525 |