CN208372313U - Neutron capture treatment system - Google Patents
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- CN208372313U CN208372313U CN201721142824.8U CN201721142824U CN208372313U CN 208372313 U CN208372313 U CN 208372313U CN 201721142824 U CN201721142824 U CN 201721142824U CN 208372313 U CN208372313 U CN 208372313U
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Abstract
The utility model provides a kind of neutron capture treatment system, can avoid or reduce the leakage of neutron and other radiation caused by the place that shielding wall or floor are passed through as component or element.The neutron capture treatment system of the utility model, including accelerator, beam transport part and the first neutron beam generating unit, accelerator carries out accelerating to generate charged particle beam to charged particle, the Transport of Charged Particle Beams that beam transport part generates accelerator is to the first neutron beam generating unit, first neutron beam generating unit generates treatment neutron beam, boron neutron capture treatment system further includes that charged particle beam generates room and the first exposure cell, charged particle beam generates room and accommodates accelerator and at least partly beam transport part, patient carries out the treatment of neutron beam irradiation in the first exposure cell, at least part of first neutron beam generating unit is embedded in the first exposure cell and charged particle beam generates the first partition wall of room, the first shield is arranged by the position that the first neutron beam generating unit passes through in the side of the first partition wall towards beam transmission direction upstream.
Description
Technical field
The utility model relates to a kind of irradiation with radiation system more particularly to a kind of neutron capture treatment systems.
Background technique
As the radiation cures such as the development of atomics, such as cobalt 60, linear accelerator, electron beam have become cancer
One of the main means of disease treatment.However conventional photonic or electronic therapy are limited by radioactive ray physical condition itself, are being killed
While dead tumour cell, normal tissue a large amount of in beam approach can also be damaged；Additionally, due to tumour cell to putting
The difference of radiation-sensitive degree, traditional radiation therapy is for relatively having the malignant tumour of radiation resistance (such as: multirow glioblast
Tumor (glioblastoma multiforme), melanocytoma (melanoma)) treatment effect it is often bad.
Target therapy in order to reduce the radiation injury of tumour surrounding normal tissue, in chemotherapy (chemotherapy)
Concept is just applied in radiation cure；And it is directed to the tumour cell of radiation resistance, also actively development has high phase at present
To the radiation source of biological effect (relative biological effectiveness, RBE), as proton therapeutic, heavy particle are controlled
Treatment, neutron capture treatment etc..Wherein, neutron capture treatment is to combine above two concept, if boron neutron capture is treated, by
Boracic drug gathers in the specificity of tumour cell, and accurately neutron beam regulates and controls for cooperation, provides more better than conventional radiation
Treatment of cancer selection.
Various radioactive ray can be generated during radiation cure, as boron neutron capture therapeutic process generates low energy to high energy
Neutron, photon, these radioactive ray may cause different degrees of damage to human normal tissue.Therefore it is led in radiation cure
Domain, how to reduce while reaching effective treatment is to the radiation pollution of external environment, medical worker or patient's normal tissue
One particularly important project.Meanwhile multiple patients cannot be treated simultaneously in the treatment of accelerator boron neutron capture at present, or
Multiple exposure cell's layouts are unreasonable, and the transmission path of charged particle beam is longer, generates loss.
Therefore, it is necessary to propose the new technical solution of one kind to solve the above problems.
Utility model content
To solve the above-mentioned problems, on the one hand the utility model provides a kind of neutron capture treatment system, including accelerates
Device, beam transport part and the first neutron beam generating unit, the accelerator carry out accelerating to generate charged particle beam, institute to charged particle
Transport of Charged Particle Beams that beam transport part generates the accelerator is stated to the first neutron beam generating unit, in described first
Beamlet generating unit generates treatment neutron beam, and the neutron capture treatment system further includes that charged particle beam generates room and the first photograph
Penetrate room, the charged particle beam generates room and accommodates the accelerator and at least partly described beam transport part, and patient is described the
The treatment of neutron beam irradiation is carried out in one exposure cell, at least part of the first neutron beam generating unit is embedded in described first
Exposure cell and the charged particle beam generate the first partition wall of room, in first partition wall towards beam transmission direction upstream
The position that is passed through by the first neutron beam generating unit of side the first shield is set.The setting of first shield can prevent from
First neutron beam generating unit is overflowed or the neutron of reflection enters charged particle beam and generates room.
Preferably, the neutron capture treatment system further includes instrument table, the first neutron beam generating unit include target,
Beam-shaping body and collimator, the target are arranged between the beam transport part and the beam-shaping body, the acceleration
The charged particle beam that device generates is irradiated to the target and acts on the target through the beam transport part generates neutron, described
The neutron of generation passes sequentially through the beam-shaping body and collimator forms treatment neutron beam and irradiates on the instrument table
Patient.
Further, the beam-shaping body includes reflector, slow body, thermal neutron absorber, radiation shield and penetrates
Beam outlet, the slow body is by from the neutron degradation that the target generates to epithermal neutron energy area, described in the reflector encirclement
Slow body and the neutron that will deviate from improve epithermal neutron intensity of beam, the thermal neutron absorber use back to the slow body
Multi-dose was caused with shallow-layer normal tissue when absorbing thermal neutron to avoid treatment, the radiation shield surrounds the beam
Outlet is arranged in the reflector rear portion and is used to shield the normal tissue dose of the neutron leaked and photon to reduce non-irradiated area,
The collimator, which is arranged, goes out metastomium in the beam to converge neutron beam, and radiation shield is arranged between the patient and beam outlet
Device is covered to shield radiation of the beam for exporting out from the beam to patient's normal tissue.
Further, the beam transport part has the vacuum tube for being accelerated to charged particle beam or being transmitted, described
Vacuum tube protrudes into the beam-shaping body along charged particle beam direction, and sequentially passes through the reflector and slow body, the target
Material is arranged in described slow in vivo and positioned at the end of the vacuum tube.
Preferably as another kind, the beam transport part includes the first transport part connecting with the accelerator, switching
The beam direction switch of charged particle beam direction of travel and by Transport of Charged Particle Beams to the first neutron beam generating unit
Second transport part, second transport part pass through first shield and reach the first neutron beam generating unit, and described first
It is towards the end of the accelerator and all with the first neutron beam generating unit that shield covers the first neutron beam generating unit
First partition wall contact enclosed.
Further, it includes accelerator room and beam transfer chamber, first transport part that the charged particle beam, which generates room,
The beam transfer chamber is extended to from the accelerator room and passes through second point of the accelerator room and the beam transfer chamber
Next door is arranged in the side of second partition wall towards beam transmission direction upstream by the position that first transport part passes through
Secondary shielding body, first transport part pass through the secondary shielding body and the second partition wall, the secondary shielding body with it is described
Second partition wall contact around first transport part.The setting of secondary shielding body can prevent from overflowing from the first transport part or anti-
The neutron penetrated enters accelerator room.
Further, the neutron capture treatment system further includes the second exposure cell and is located in second exposure cell
The second neutron beam generating unit, the beam transport part includes by Transport of Charged Particle Beams to the second neutron beam generating unit
Third transport part, the third transport part extend to second exposure cell from the beam transfer chamber and pass through the beam and pass
The third partition wall of defeated room and the second exposure cell, the third partition wall towards beam transmission direction upstream side by described
Third shield is arranged in the position that third transport part passes through, and the third transport part passes through the third shield and third separates
Wall, the third shield are contacted with the third partition wall around the third transport part.The setting energy of third shield
The neutron that prevents from overflowing from the second exposure cell or reflect enters beam transfer chamber.
Further, in X/Y plane, the third passes the transmission direction of first transport part and the second transport part
Defeated portion is transmitted along Z-direction, and the third partition wall is the floor of the beam transfer chamber or the second exposure cell.
Further, the beam direction switch includes the first, second beam direction switch, the neutron capture
Treatment system further includes third exposure cell and at least part is embedded in the third exposure cell and charged particle beam generates room
The third neutron beam generating unit of 4th partition wall, the beam transport part include by Transport of Charged Particle Beams to the third neutron
4th transport part of beam generating unit and the 5th transport part of connection the first, second beam direction switch, described first passes
Defeated portion branches into the third transport part and the 5th transport part, the 5th transport part in the first beam direction switch
Second transport part and the 4th transport part are branched into the second beam direction switch, in the 4th partition wall court
The position passed through to the side of beam transmission direction upstream by the third neutron beam generating unit is arranged the 4th shield, and described the
Four transport parts pass through the 4th shield and reach the third neutron beam generating unit, and the 4th shield covers the third
Neutron beam generating unit towards the accelerator end and with the 4th partition wall around the third neutron beam generating unit
Contact.The neutron that the setting of 4th shield can be prevented from overflowing from third neutron beam generating unit or be reflected enters charged particle beam life
At room.First transport part and the 5th transport part are transmitted along the x axis, and described second, the transmission direction of the 4th transport part exists
It is in X/Y plane and Y-shaped with the transmission direction of first transport part.Using such arrangement mode, can be effectively utilized
Space, while multiple patients are treated, and the route without excessively extending beam transmission, it is lost smaller.
On the other hand the utility model provides a kind of neutron capture treatment system, including accelerator, beam transport part, in
Beamlet generating unit, the accelerator carry out charged particle to accelerate to generate charged particle beam, and the beam transport part described will add
The Transport of Charged Particle Beams that fast device generates to the neutron beam generating unit, the neutron beam generating unit generates treatment neutron beam,
The neutron capture treatment system further includes accelerator room, beam transfer chamber and exposure cell, and the charged particle beam, which generates room, to be held
Receive the accelerator, the beam transfer chamber at least partly accommodates the beam transport part, and patient carries out in the exposure cell
The treatment of neutron beam irradiation, the beam transport part pass through the accelerator room, the first partition wall of beam transfer chamber and/or institute
The second partition wall for stating beam transfer chamber and exposure cell is transmitted in first partition wall and/or the second partition wall towards beam
Shield is arranged by the position that the beam transport part passes through in the side of direction upstream.The setting of shield can be prevented from beam
Transport part and/or exposure cell are overflowed or the neutron of reflection enters accelerator room and/or beam transfer chamber.
The neutron capture treatment system of the utility model can be avoided or reduced in shielding wall or floor by component or element
The leakage of neutron caused by the place passed through and other radiation.
Detailed description of the invention
Fig. 1 is the neutron capture treatment system structural schematic diagram in the utility model embodiment；
Fig. 2 is schematic layout pattern of the neutron capture treatment system in the utility model embodiment in X/Y plane；
Fig. 3 is schematic diagram of the Fig. 2 in A-A section.
Specific embodiment
The embodiments of the present invention are described in further detail with reference to the accompanying drawing, to enable those skilled in the art
Refer to the instruction text can be implemented accordingly.Set the direction of charged particle beam P of projecting aftermentioned accelerator as X-axis,
The direction that the direction of the charged particle beam P projected with accelerator is orthogonal as Y-axis, using the direction vertical relative to ground as
The XYZ coordinate system (referring to figs. 2 and 3) of Z axis, and X, Y, Z are used in the explanation of the positional relationship in each constitutive requirements.
Such as Fig. 1, the neutron capture treatment system in the present embodiment is preferably boron neutron capture treatment system 100, boron neutron
Capture treatment system 100 is the device that treatment of cancer is carried out using boron neutron capture therapy.Boron neutron capture therapy passes through to note
The patient 200 for penetrating boron (B-10) irradiates neutron beam N to carry out treatment of cancer, and patient 200 takes or inject boracic (B-10) medicine
It after object, is gathered in tumour cell M to boracic drug selectivity, then thermal neutron is caught with height using boracic (B-10) drug
The characteristic for obtaining section, by10B(n,α)7Li neutron capture and nuclear fission reaction generate4He and7Two heavy burden charged particle of Li.Two lotuses
The average energy of charged particle is about 2.33MeV, and there is High Linear to shift (Linear Energy Transfer, LET), short range
Feature, the linear energy transfer of the short particle of α and range are respectively 150keV/ μm, 8 μm, and7Li heavy burden particle is then 175keV/
μm, 5 μm, the integrated range of two particle is approximately equivalent to a cell size, therefore the radiation injury for caused by organism can be limited to
In cell level, just it can achieve the purpose that tumour cell is killed in part under the premise of normal tissue does not cause too major injury.
Boron neutron capture treatment system 100 includes accelerator 10, beam transport part 20, neutron beam generating unit 30 and instrument table
40.Accelerator 10 accelerates charged particle (such as proton, deuteron), generates the charged particle beam P such as proton beam；Beam passes
The charged particle beam P that accelerator 10 generates is transmitted to neutron beam generating unit 30 by defeated portion 20；Neutron beam generating unit 30 generates treatment
With neutron beam N and irradiate the patient 200 on instrument table 40.
Neutron beam generating unit 30 includes target T, beam-shaping body 31, collimator 32, the charged particle that accelerator 10 generates
Beam P is irradiated to target T and acts on target T through beam transport part 20 generates neutron, and the neutron of generation passes sequentially through beam-shaping
Body 31 and collimator 32 form treatment neutron beam N and irradiate the patient 200 on instrument table 40.Target T is preferably metallic target
Material.According to required neutron yield rate and energy, the available materialization for accelerating charged particle energy and size of current, metal targets
The characteristics such as property select suitable nuclear reaction, and the nuclear reaction being often discussed has7Li(p,n)7Be and9Be(p,n)9B, both are anti-
It should be all the endothermic reaction.The energy threshold of two kinds of nuclear reactions is respectively 1.881MeV and 2.055MeV, since boron neutron capture is controlled
The ideal neutron source for the treatment of is the epithermal neutron of keV energy grade, if being theoretically only slightly taller than the proton bombardment of threshold values using energy
Lithium metal target can produce the neutron of opposite low energy, and clinic can be used for by being not required to too many slow handle, however lithium metal (Li)
It is not high with two kinds of targets of beryllium metal (Be) and the proton-effect section of threshold values energy, to generate sufficiently large neutron flux, usually
The proton of higher-energy is selected to cause nuclear reaction.Ideal target should have the neutron energy distribution of high neutron yield rate, generation
Radiation generation, the cheap easily operated and resistance to height of safety are worn by force close to epithermal neutron energy area (will be described in more detail below), without too many
The characteristics such as temperature, but actually and can not find and meet required nuclear reaction.It is well known to those skilled in the art, target T
It can be made of the metal material except Li, Be, such as be formed by Ta or W and its alloy etc..Accelerator 10 can be straight line and add
Fast device, cyclotron, synchrotron, synchrocyclotron.
Beam-shaping body 31 can adjust the beam quality for the neutron beam N that charged particle beam P and target T effect generates, quasi-
Straight device 32 makes neutron beam N targeting with higher during being treated to converge neutron beam N.Beam-shaping body
31 further comprise reflector 311, slow body 312, thermal neutron absorber 313, radiation shield 314 and beam outlet 315, band
The neutron that electrochondria beamlet P and target T effect generates other than epithermal neutron meets treatment needs, is needed since power spectrum is very wide
Other kinds of neutron is reduced as far as possible and photon content damages to avoid to operator or patient, therefore from target
The neutron that T comes out needs that fast neutron energy therein (> 40keV) is adjusted to epithermal neutron energy area by slow body 312
(0.5eV-40keV) and as far as possible reduce thermal neutron (< 0.5eV), slow body 312 by with fast neutron action section it is big, it is superthermal in
The small material of sub- action section is made, and in the present embodiment, slow body 312 is by D2O、AlF3、Fluental、CaF2、Li2CO3、
MgF2And Al2O3At least one of be made；Reflector 311 surrounds slow body 312, and passes through slow body 312 and spread around
Neutron reflection return neutron beam N to improve the utilization rate of neutron, by being made with the strong material of neutron reflection ability, this implementation
In example, reflector 311 is made of at least one of Pb or Ni；There is a thermal neutron absorber 313 at slow 312 rear portion of body, by
Big material is made with thermal neutron action section, and in the present embodiment, thermal neutron absorber 313 is made of Li-6, neutron absorption
Body 313 is used to absorb the thermal neutron across slow body 312 to reduce the content of thermal neutron in neutron beam N, when avoiding treating and shallowly
Layer normal tissue caused multi-dose；Radiation shield 314 is arranged around beam outlet 315 at reflector rear portion, for shielding
The neutron and photon leaked from beam outlet 315 with outer portion, the material of radiation shield 314 include photon shielding material in
At least one of sub- shielding material, in the present embodiment, the material of radiation shield 314 includes photon shielding material lead (Pb)
With neutron shielding material polyethylene (PE).It is appreciated that beam-shaping body 31 can also have other constructions, as long as can obtain
Epithermal neutron beam needed for treating.The setting of collimator 32 exports 315 rear portions in beam, the epithermal neutron come out from collimator 32
Beam is irradiated to patient 200, is slowly that thermal neutron reaches tumour cell M after shallow-layer normal tissue, it will be understood that collimator 32
It can also cancel or be replaced by other structures, neutron beam comes out from beam outlet 315 directly to be irradiated to patient 200.The present embodiment
In, it is also provided with radiation shield device 50 between patient 200 and beam outlet 315, shields and is penetrated from what beam outlet 315 came out
Radiation of the beam to patient's normal tissue, it will be understood that radiation shield device 50 can also be not provided with.Target T setting is passed in beam
Between defeated portion 20 and beam-shaping body 31, beam transport part 20 has the vacuum tube that charged particle beam P is accelerated or transmitted
C, in the present embodiment, vacuum tube C protrudes into beam-shaping body 31 along the direction charged particle beam P, and it is gentle to sequentially pass through reflector 311
Fast body 312, the end in slow body 312 and being located at vacuum tube C is arranged in target T, to obtain preferable neutron beam quality.It can
To understand, target can have other set-up modes, can also opposite accelerator or beam-shaping body be it is movable, to facilitate
It changes target or makes charged particle beam and target stepless action.
In conjunction with Fig. 2 and Fig. 3, boron neutron capture treatment system 100 is integrally provided in the space of two floor L1 and L2, boron neutron
Capture treatment system 100 further includes that exposure cell 101 (101A, 101B, 101C) and charged particle beam generate room 102, instrument table 40
On patient 200 treatment of neutron beam N irradiation is carried out in exposure cell 101 (101A, 101B, 101C), charged particle beam generates
Room 102 accommodates accelerator 10 and at least partly beam transport part 20.Neutron beam generating unit 30 can have one or more, to generate
One or more treatment neutron beam N, beam transport part 20 is selectively to one or several 30 transmission belts of neutron beam generating unit
Electrochondria beamlet P transmits charged particle beam P to multiple neutron beam generating units 30 simultaneously, and each neutron beam generating unit 30 is one corresponding
Exposure cell 101.Respectively there are 3, respectively neutron beam generating unit 30A, 30B, 30C in neutron beam generating unit and exposure cell in the present embodiment
With exposure cell 101A, 101B, 101C.Beam transport part 20 includes: the first transport part 21, is connect with accelerator 10；First, second
Beam direction switch 22,23 switches the direction of travel of charged particle beam P；Second transport part 24 connects the first, second beam
Direction switcher 22,23；Third, the four, the 5th transport part 25A, 25B, 25C, respectively by charged particle beam P from the first beam side
Neutron beam generating unit 30A, 30B, 30C, the neutron beam N of generation are transferred to switch 22 or the second beam direction switch 23
Irradiate the patient into exposure cell 101A, 101B, 101C respectively again.Third transport part 25A connection the first beam direction switch
22 and neutron beam generating unit 30A, the 4th transport part 25B the second beam direction of connection switch 23 and neutron beam generating unit 30B,
5th transport part 25C the second beam direction of connection switch 23 and neutron beam generating unit 30C.That is, the first transport part 21 is first
The second transport part 24 and third transport part 25A are branched into beam direction switch 22, the second transport part 24 is again in the second beam
The 4th transport part 25B and the 5th transport part 25C is branched into direction switcher 23.First, second transport part 21,24 is along X-axis side
To transmission, third transport part 25A is transmitted along Z-direction, and the transmission direction of the four, the 5th transport part 25B, 25C is in X/Y plane
And, neutron beam generating unit 30A, 30B, 30C and corresponding irradiation Y-shaped with the transmission direction of the first, second transport part 21,24
Room 101A, 101B, 101C are arranged along third, the transmission direction of the four, the 5th transport part 25A, 25B, 25C respectively, in generation
The direction beamlet N is identical as the transmission direction of third, the four, the 5th transport part 25A, 25B, 25C respectively, so that neutron beam generates
Portion 30B, 30C generate neutron beam direction in the same plane, neutron beam generating unit 30A generate neutron beam direction and the plane
Vertically.Using such arrangement mode, space can be effectively utilized, while multiple patients are treated, and without excessively
Extend the route of beam transmission, is lost smaller.It is appreciated that the neutron beam side N that neutron beam generating unit 30A (30B, 30C) is generated
It can also be different to the transmission direction with third (the four, the 5th) transport part 25A (25B, 25C)；First, second transport part 21,
24 transmission direction can also be different, and the second transport part 24 can also cancel, and only have a beam direction switch, by beam
Branch into 2 and 2 or more hops；The transmission direction of four, the 5th transport part 25B, 25C and the biography of the first transport part 21
The Y-shaped that defeated direction is formed, is also possible to the deformation of " Y ", such as the transmission side of the 4th transport part 25B or the 5th transport part 25C
To, the transmission direction of four, fiveth transport part 25B, 25Cs and first transport part identical as the transmission direction of the first transport part 21
21 transmission direction can also be in other shapes, such as T-shape or arrowhead-shaped, as long as the transmission of the four, the 5th transport part 25B, 25C
Direction forms the angle greater than 0 degree in XY plane；The transmission direction of four, the 5th transport part 25B, 25C is also not necessarily limited to XY
The transmission direction of plane, third transport part 25A may not be along Z axis, as long as the transmission direction of the 4th transport part 25B, the 5th
The transmission direction of transport part 25C and two therein of the transmission direction of the first transport part 21 in same plane (the first plane),
The transmission direction of first transport part 21 and the transmission direction of third transport part 25A are also interior in same plane (the second plane), and the
One plane and the second plane difference；Third transport part 25A, neutron beam generating unit 30A and exposure cell 101A can also cancel, in this way
Only with the beam transmission in X/Y plane.
First, second beam direction switch 22,23 includes the deflection electromagnet for deflecting the direction charged particle beam P and control
The switch electromagnet of charged particle beam P direction of travel processed, boron neutron capture treatment system 100 can also include beam trap
(not shown), the before the treatment equal output confirmation for carrying out charged particle beam P, first or second beam direction switch 22,23 energy
Charged particle beam P is enough set to be detached from regular track and guide beam trap into.
First transport part 21, the second transport part 24 and third, the four, the 5th transport part 25A, 25B, 25C are by vacuum tube
C construction, can be connected respectively by multiple sub- transport parts and be formed, and the transmission directions of multiple sub- transport parts can be identical or not
Together, such as the deflection by deflection electromagnet progress beam transmission direction, the described first, second, third, fourth, the 5th transmission
Portion 21,24, the transmission direction of 25A, 25B, 25C can be the transmission direction of its any sub- transport part, and the first of above-mentioned formation is flat
Face and the second plane are the plane formed between the sub- transport part being connected directly with beam direction switch；It can also respectively include
For the beam adjustment section (not shown) of charged particle beam P, beam adjustment section includes the water for adjusting the axis of charged particle beam P
Flat pattern diverter and horizontal vertical type diverter, diverging for inhibiting charged particle beam P quadrupole electromagnet and be used for band
The four-way cutter of shaping etc. of electrochondria beamlet P.Third, the four, the 5th transport part 25A, 25B, 25C can include electricity as needed
Flow monitor (not shown) and charged particle beam scanner section (not shown).Current monitor the real time measure is irradiated in the electrification of target T
The current value (that is, charge, exposure dose rate) of particle beams P.Charged particle beam scanner section scans charged particle beam P, is charged
Particle beams P is controlled relative to the irradiation of target T, such as controls irradiation position of the charged particle beam P relative to target T.
It may include accelerator room 1021 and beam transfer chamber 1022, accelerator room 1021 that charged particle beam, which generates room 102,
It is two layers, accelerator 10 extends to L1 from L2.Beam transfer chamber 1022 is located at L2, and the first transport part 21 is from accelerator room 1021
Extend to beam transfer chamber 1022.Exposure cell 101B, 101C are located at L2, and exposure cell 101A is located at L1.L1 is in L2 in the present embodiment
Lower section, the i.e. floor of L2 are the ceiling of L1, it is possible to understand that, or opposite configuration.The material of floor (ceiling) S
It can be the concrete or boracic baryte of thickness 0.5m or more.Exposure cell 101A, 101B, 101C and beam transfer chamber
1022 have the shielding space surrounded by shielding wall W1, and shielding wall W1 can be the boracic of thickness 1m or more, density 3g/c.c.
Baryte wall, including separate beam transfer chamber 1022 and exposure cell 101B, 101C the first compartment shield wall W2 and
The second compartment shield wall W3 of accelerator room 1021 and beam transfer chamber 1022 is separated in L1, separates accelerator room 1021 in L2
With the third compartment shield wall W4 of exposure cell 101A.Accelerator room 1021 is by with a thickness of the concrete wall W of 1m or more and second point
It is surrounded every shielding wall W3, third compartment shield wall W4.At least part of neutron beam generating unit 30B, 30C is embedded in first point
Neutron beam generating unit 30B, 30C is extended to from beam transfer chamber 1022 every shielding wall W2, the four, the 5th transport part 25B, 25C；
Neutron beam generating unit 30A is located in exposure cell 101A, and third transport part 25A passes through floor S from beam transfer chamber 1022 and extends to
Exposure cell 101A.Exposure cell 101A, 101B, 101C are respectively provided with shield door D1, D2, D3 for instrument table 40 and doctor's discrepancy,
Accelerator room 1021 is respectively provided with shield door D4, D5 that accelerator 10 is safeguarded in disengaging accelerator Room 1021 in L1 and L2,
Beam transfer chamber 1022, which has from accelerator room 1021, passes in and out the screen that beam transfer chamber 1022 safeguards beam transport part 20
A D6 is covered, shield door D6 is arranged on the second compartment shield wall W3.The indoor of exposure cell 101A, 101B, 101C also has interior screen
Wall W5 is covered, to form the labyrinth type channel exported from shield door D1, D2, D3 to beam, prevents shield door D1, D2, D3 from surprisingly beating
The direct irradiation of radiation when opening can be set in different positions, inside according to the different layout inner shield wall W5 of exposure cell
Shield door D7 inside exposure cell can also be set between shielding wall W5 and shielding wall W1 or third compartment shield wall W4, be formed in
Carry out secondary protection when neutron beam irradiation treatment.It is containing for 3g/c.c. that inner shield wall W5, which can be thickness 0.5m or more, density,
Boron baryte wall；Shield door D1, D2, D3, D4, D5, D6, D7 can be by two layers of independent main shield door D and secondary screens
It covers D ' composition or is only made of main shield door D or secondary shield door D ', can be determined according to practical situation, main shield door D can be with
It is the PE or baryte or lead of the boracic with a thickness of 0.5m or more, density 6g/c.c. of identical material, secondary shield door D '
It can be the PE or baryte or lead of the boracic with a thickness of 0.2m or more, density 6g/c.c. of identical material.This implementation
In example, shield door D1, D4, D5, D6 are made of main shield door D and secondary shield door D ', and shield door D1, D2, D3 only include main shield
Door D, shield door D7 only include time shield door D '.Shielding wall and shield door form shielding space, inhibit radioactive ray from exposure cell
The outdoor of 101A, 101B, 101C and beam transfer chamber 1022 invades indoor and radioactive ray and emits to outdoor phenomenon from interior.
In the present embodiment, the second compartment shield wall W3 for separating accelerator room 1021 and beam transfer chamber 1022 is arranged in 10 He of accelerator
Between first beam direction switch 22, i.e. the first transport part 21 passes through the second compartment shield wall W3, it will be understood that second separates
Shielding wall W3 and shield door D6 can cancel, and also can be set in other positions, such as the first, second beam direction switch 22,
Between 23 or between the second beam direction switch 23 and neutron beam generating unit 30B, 30C；Or in the second compartment shield wall W3 and
Additional compartment shield wall and shield door are set between first compartment shield wall W2.That is, in neutron beam generating unit and adding
Shielding wall is set between fast device, when accelerator overhauls and safeguards operator from the neutron that is leaked from neutron beam generating unit and
The irradiation of other radiation, while reducing reaction of the accelerator by neutron activation.
Neutron and the leakage of other radiation are be easy to cause by the place that component or element pass through in shielding wall or floor, such as
In the present embodiment, neutron beam generating unit 30B, 30C passes through the first compartment shield wall W2, the first transport part 21 passes through the second panel superheater
Wall W3, third transport part 25A are covered across floor S, in the first compartment shield wall W2, the second compartment shield wall W3, floor S direction
The side of beam transmission direction upstream is passed through by neutron beam generating unit 30B, 30C, the first transport part 21, third transport part 25A
The first shield 60, secondary shielding body 70 and third shield 80 can be respectively set in position.First shield 60 covers neutron
Beam generating unit 30B, 30C towards accelerator end and with the first compartment shield wall W2 around neutron beam generating unit 30B, 30C
Contact, the neutron that prevents from overflowing from the beam-shaping body of neutron beam generating unit 30B, 30C or reflect enter 1021 and of accelerator room
Beam transfer chamber 1022, the four, the 5th transport part 25B, 25C pass through the first shield 60 and reach neutron beam generating unit 30B, 30C
Target T.Secondary shielding body 70 is contacted with the second compartment shield wall W3 around the first transport part 21, is prevented from beam transport part
20 neutrons for overflowing or reflecting enter accelerator room 1021, and the first transport part 21 passes through secondary shielding body 70 and the second compartment shield
Wall W3 reaches the first beam direction switch 22.Floor S contact around third shield 80 and third transport part 25A, prevents
The neutron for overflowing or reflecting from exposure cell 101A enters beam transfer chamber 1022, and third transport part 25A passes through third shield 80
Neutron beam generating unit 30A is reached with floor S.The material of first shield 60, secondary shielding body 70 and third shield 80 can be with
For the PE or baryte or lead of boracic.
First, second beam direction switch 22,23 is surrounded by shielding case 26 respectively, prevents from letting out from beam direction switch
Neutron and other radiation are leaked, the material of shielding case 26 can be the PE or baryte or lead of boracic.It is appreciated that the
One, the second beam direction switch 22,23 can also be surrounded integrally by a shielding case 26；The other parts of beam transport part,
It such as vacuum tube, can also be surrounded by shielding case, prevent neutron and other radiation from revealing from beam transport part.
Boron neutron capture treatment system 100 can also include preparation room, control room and other for adjuvant treatment spaces,
Each exposure cell can configure a preparation room, for be irradiated treat before immobilized patients to instrument table, inject boron medicine, control
The preparations such as plan simulation are treated, interface channel is set between preparation room and exposure cell, and preparation is after the completion directly by patient
Push-in exposure cell controls it automatically into exposure cell by control mechanism by track, and preparation room and interface channel are also by shielding wall
Closing, preparation room also have shield door.Control room is irradiated for controlling accelerator, beam transport part, instrument table etc. to entire
Cheng Jinhang control and management, administrative staff can also monitor multiple exposure cells simultaneously in control room.
It is appreciated that shielding wall (including concrete wall W), shield door, shield, the shielding case in the present embodiment can be with
With other thickness or density or replace with other materials.
Although the illustrative specific embodiment of the utility model is described above, in order to the art
Technical staff understands the utility model, it should be apparent that the utility model is not limited to the range of specific embodiment, to this technology
For the those of ordinary skill in field, as long as various change is in the essence of the utility model that the attached claims limit and determine
In mind and range, these variations are it will be apparent that all within the scope of the requires of the utility model protection.
Claims (10)
1. a kind of neutron capture treatment system, including accelerator, beam transport part and the first neutron beam generating unit, the accelerator
Charged particle is carried out to accelerate to generate charged particle beam, the charged particle beam that the beam transport part generates the accelerator passes
The first neutron beam generating unit is transported to, the first neutron beam generating unit generates treatment neutron beam, which is characterized in that described
Neutron capture treatment system further includes that charged particle beam generates room and the first exposure cell, and the charged particle beam generates room and accommodates institute
Accelerator and at least partly described beam transport part are stated, patient carries out the treatment of neutron beam irradiation in first exposure cell,
At least part of the first neutron beam generating unit is embedded in first exposure cell and the charged particle beam generates room
First partition wall is worn in the side of first partition wall towards beam transmission direction upstream by the first neutron beam generating unit
The first shield is arranged in the position crossed.
2. neutron capture treatment system as described in claim 1, which is characterized in that the neutron capture treatment system further includes
Instrument table, the first neutron beam generating unit include target, beam-shaping body and collimator, and the target is arranged in the beam
Between transport part and the beam-shaping body, the charged particle beam that the accelerator generates is irradiated to institute through the beam transport part
It states target and is acted on the target and generate neutron, the neutron of the generation passes sequentially through the beam-shaping body and collimator shape
At treatment neutron beam and irradiate the patient on the instrument table.
3. neutron capture treatment system as claimed in claim 2, which is characterized in that the beam-shaping body include reflector,
Slow body, thermal neutron absorber, radiation shield and beam outlet, the neutron degradation that the slow body will be generated from the target
To epithermal neutron energy area, the reflector surrounds the slow body and the neutron that will deviate from is super to improve back to the slow body
Thermal neutron intensity of beam caused when the thermal neutron absorber is for absorbing thermal neutron to avoid treatment with shallow-layer normal tissue
Multi-dose, the radiation shield around the beam outlet be arranged in the reflector rear portion for shield leakage neutron with
For photon to reduce the normal tissue dose in non-irradiated area, the collimator, which is arranged, goes out metastomium in the beam to converge neutron
Radiation shield device is arranged to shield the beam for exporting out from the beam to patient in beam between the patient and beam outlet
The radiation of normal tissue.
4. neutron capture treatment system as claimed in claim 3, which is characterized in that the beam transport part has to band electrochondria
The vacuum tube that beamlet is accelerated or transmitted, the vacuum tube protrude into the beam-shaping body along charged particle beam direction, and according to
Secondary to pass through the reflector and slow body, the target is arranged in described slow in vivo and positioned at the end of the vacuum tube.
5. neutron capture treatment system as described in claim 1, which is characterized in that the beam transport part includes adding with described
First transport part of fast device connection, the beam direction switch for switching charged particle beam direction of travel and by Transport of Charged Particle Beams
To the second transport part of the first neutron beam generating unit, second transport part passes through first shield and reaches described the
One neutron beam generating unit, first shield cover the first neutron beam generating unit towards the end of the accelerator and with
First partition wall contact around the first neutron beam generating unit.
6. neutron capture treatment system as claimed in claim 5, which is characterized in that it includes adding that the charged particle beam, which generates room,
Fast device room and beam transfer chamber, first transport part extend to the beam transfer chamber from the accelerator room and pass through described
Second partition wall of accelerator room and the beam transfer chamber, in second partition wall towards the one of beam transmission direction upstream
The position that side is passed through by first transport part is arranged secondary shielding body, first transport part pass through the secondary shielding body and
Second partition wall, the secondary shielding body are contacted with second partition wall around first transport part.
7. neutron capture treatment system as claimed in claim 6, which is characterized in that the neutron capture treatment system further includes
Second exposure cell and it is located at the indoor second neutron beam generating unit of second irradiation, the beam transport part includes will be with electrochondria
Beamlet is transferred to the third transport part of the second neutron beam generating unit, and the third transport part extends from the beam transfer chamber
To second exposure cell and across the third partition wall of the beam transfer chamber and the second exposure cell, in the third partition wall
Third shield is arranged by the position that the third transport part passes through towards the side of beam transmission direction upstream, the third passes
Defeated portion passes through the third shield and third partition wall, and described the around the third shield and the third transport part
The contact of three partition walls.
8. neutron capture treatment system as claimed in claim 7, which is characterized in that first transport part and the second transport part
Transmission direction in X/Y plane, the third transport part along Z-direction transmit, the third partition wall be the beam transmit
The floor of room or the second exposure cell.
9. neutron capture treatment system as claimed in claim 8, which is characterized in that the beam direction switch includes the
One, the second beam direction switch, the neutron capture treatment system further include that third exposure cell and at least part are embedded in
The third exposure cell and charged particle beam generate the third neutron beam generating unit of the 4th partition wall of room, the beam transport part
Including by Transport of Charged Particle Beams to the 4th transport part of the third neutron beam generating unit and connection first, second beam
5th transport part of direction switcher, first transport part branch into the third in the first beam direction switch
Transport part and the 5th transport part, the 5th transport part branch into second transmission in the second beam direction switch
Portion and the 4th transport part are generated in the side of the 4th partition wall towards beam transmission direction upstream by the third neutron beam
The 4th shield is arranged in the position that portion passes through, and the 4th transport part passes through the 4th shield and reaches the third neutron beam
Generating unit, the 4th shield cover the third neutron beam generating unit towards the end of the accelerator and with the third
The 4th partition wall contact around neutron beam generating unit, first transport part and the 5th transport part are transmitted along the x axis,
Described second, the transmission direction of the 4th transport part is in X/Y plane and Y-shaped with the transmission direction of first transport part.
10. a kind of neutron capture treatment system, including accelerator, beam transport part, neutron beam generating unit, the accelerator is to band
Charged particle carries out accelerating to generate charged particle beam, and the Transport of Charged Particle Beams that the beam transport part generates the accelerator is extremely
The neutron beam generating unit, the neutron beam generating unit generate treatment neutron beam, which is characterized in that the neutron capture treatment
System further includes accelerator room, beam transfer chamber and exposure cell, and the charged particle beam generates room and accommodates the accelerator, described
Beam transfer chamber at least partly accommodates the beam transport part, and patient carries out the treatment of neutron beam irradiation in the exposure cell,
The beam transport part passes through the accelerator room, the first partition wall of beam transfer chamber and/or the beam transfer chamber and photograph
The second partition wall for penetrating room, first partition wall and/or the second partition wall towards beam transmission direction upstream side by
Shield is arranged in the position that the beam transport part passes through.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201721142824.8U CN208372313U (en) | 2017-09-07 | 2017-09-07 | Neutron capture treatment system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201721142824.8U CN208372313U (en) | 2017-09-07 | 2017-09-07 | Neutron capture treatment system |
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| Publication Number | Publication Date |
|---|---|
| CN208372313U true CN208372313U (en) | 2019-01-15 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201721142824.8U Withdrawn - After Issue CN208372313U (en) | 2017-09-07 | 2017-09-07 | Neutron capture treatment system |
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| CN (1) | CN208372313U (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109464751A (en) * | 2017-09-07 | 2019-03-15 | 南京中硼联康医疗科技有限公司 | Neutron capture treatment system |
| TWI734408B (en) * | 2019-03-18 | 2021-07-21 | 中國商中硼（廈門）醫療器械有限公司 | Neutron Capture Therapy System |
| TWI741558B (en) * | 2019-04-17 | 2021-10-01 | 中國商中硼（廈門）醫療器械有限公司 | Neutron Capture Therapy System |
-
2017
- 2017-09-07 CN CN201721142824.8U patent/CN208372313U/en not_active Withdrawn - After Issue
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109464751A (en) * | 2017-09-07 | 2019-03-15 | 南京中硼联康医疗科技有限公司 | Neutron capture treatment system |
| CN109464751B (en) * | 2017-09-07 | 2024-03-22 | 南京中硼联康医疗科技有限公司 | Neutron capture therapy system |
| TWI734408B (en) * | 2019-03-18 | 2021-07-21 | 中國商中硼（廈門）醫療器械有限公司 | Neutron Capture Therapy System |
| US11826583B2 (en) | 2019-03-18 | 2023-11-28 | Neuboron Therapy System Ltd. | Neutron capture therapy system |
| TWI741558B (en) * | 2019-04-17 | 2021-10-01 | 中國商中硼（廈門）醫療器械有限公司 | Neutron Capture Therapy System |
| TWI786791B (en) * | 2019-04-17 | 2022-12-11 | 中國商中硼（廈門）醫療器械有限公司 | Beam Shapers for Neutron Capture Therapy Systems |
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