CN208292136U - A kind of packaging system of Couteat of Folic Acid - Google Patents
A kind of packaging system of Couteat of Folic Acid Download PDFInfo
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- CN208292136U CN208292136U CN201820861920.6U CN201820861920U CN208292136U CN 208292136 U CN208292136 U CN 208292136U CN 201820861920 U CN201820861920 U CN 201820861920U CN 208292136 U CN208292136 U CN 208292136U
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Abstract
The utility model relates to a kind of packaging system of Couteat of Folic Acid, including the first-the five surface sterilization unit, the first-the four weighing unit, purifying water unit, unit with slurry, pulverize and sieve unit, pelletization unit, drying unit, total mix unit, pelletizing unit, inner packing unit, outer packing unit.First-the four surface sterilization unit is corresponding with the first-the four weighing unit to be connected, first and second weighing units are connected with unit with slurry, unit with slurry is connected with pelletization unit, second and third weighing unit be connected with pelletization unit, pelletization unit is connected with drying unit, drying unit is connected with total mix unit, and the 4th weighing unit is connected with total mix unit;Total mix unit is connected with pelletizing unit, and pelletizing unit is connected with inner packing unit, and inner packing unit is connected with outer packing unit;Unit with slurry is connect with purifying water unit;Inner packing unit is connect with the 5th surface sterilization unit.The production process of the utility model is simple and compact.
Description
Technical field
The utility model belongs to pharmaceutical production and packing technique field, is a kind of packaging system of Couteat of Folic Acid more specifically.
Background technique
Couteat of Folic Acid is widely applicable to megaloblastic anemia caused by folic acid deficiency caused by a variety of causes and folic acid deficiency
Folic acid deficiency caused by disease, chronic hemolytic anemia, and be the gestational period, breast feeding women's prevention administration.
Couteat of Folic Acid production and packaging process are using material appropriate or container, pass through production and packing technique to Couteat of Folic Acid
The layout and configuration of the entire process of production.The case where existing production and packaging process are more complex, are easy to appear mispacking,
Influence the yield rate of Key works Drug packing.
Utility model content
The purpose of the utility model is to provide a kind of production of Couteat of Folic Acid and the composition system of packaging process, production process letters
It is single, compact.
In order to complete above-mentioned purpose, the utility model discloses a kind of packaging systems of Couteat of Folic Acid, which is characterized in that packet
It includes:
Surface sterilization device, the surface sterilization device include first surface disinfection unit, second surface disinfection unit, third
Surface sterilization unit, the 4th surface sterilization unit and the 5th surface sterilization unit, respectively to raw material folic acid, cornstarch,
Glucose, magnesium stearate and inner packaging material carry out surface sterilization;
Meausring apparatus, the meausring apparatus include the first weighing unit, the second weighing unit, third weighing unit, the 4th title
Unit is measured, respectively to weigh raw material folic acid, cornstarch, glucose, magnesium stearate;
Water unit is purified, to produce purified water;
Unit with slurry, to use purified water preparation to stir the bonding slurries formed by folic acid and cornstarch;
Unit is pulverized and sieved, to be crushed and be sieved to glucose;
Pelletization unit to mix glucose, cornstarch, and is added bonding slurries and is mixed and made into softwood, and will be soft
Wet granular is made in material;
Drying unit carries out whole grain to dry wet particle, and to the particle after drying;
Total mix unit is mixed the particle for passing through whole grain to be added in magnesium stearate;
Pelletizing unit, mixed granulation processing is formed tablet;
Inner packing unit, to pack the tablet for passing through tabletting using inner packaging material;
Outer packing unit, the tablet will pack through inner packaging material carry out double aluminium packagings;
Wherein, the first surface disinfection unit is connected with the first weighing unit, the second surface disinfection unit and
Two weighing units are connected, and the third surface sterilization unit is connected by pulverizing and sieving unit with third weighing unit, and described the
Four surface sterilization units are connected with the 4th weighing unit;
First weighing unit and the second weighing unit are connected with unit with slurry, the unit with slurry and pelletization unit phase
Even, the third weighing unit is connected with pelletization unit, and second weighing unit is connected with pelletization unit;
The pelletization unit is connected with drying unit, and the drying unit is connected with total mix unit, and the described 4th weighs list
Member is connected with total mix unit;
The total mix unit is connected with pelletizing unit, and the pelletizing unit is connected with inner packing unit, the inner packing list
Member is connected with outer packing unit;
The unit with slurry is also connect with purifying water unit;
The inner packing unit is also connect with the 5th surface sterilization unit.
Preferably, the surface sterilization device is pass-through box, which is arranged ultraviolet emission device.
Preferably, the unit that pulverizes and sieves includes efficient universal pulverizer, and the sieve of the efficient universal pulverizer is 100
Mesh screen.
Preferably, the pelletization unit includes efficient wet mixer-granulator, oscillating granulator, and in the oscillating granulator
24 mesh nylon mesh of upper installation.
Preferably, the drying unit includes to the heated-air circulation oven of dry wet particle, to after drying
Grain carries out 24 mesh nylon screens of whole grain.
Preferably, the total mix unit includes Mixers with Multi-direction Movement.
Preferably, the pelletizing unit includes rotary tablet machine.
Preferably, the outer packing unit includes double aluminum foil packing machine.
The application's has the technical effect that the utility model is the composition system of Couteat of Folic Acid production and packaging process, life
Production process is simple, compact-sized, high production efficiency.
Detailed description of the invention
Fig. 1 is the flowage structure schematic diagram of the utility model.
Specific embodiment
Below with reference to the attached drawing in the utility model embodiment, the technical scheme in the embodiment of the utility model is carried out clear
Chu is fully described by.Many details are explained in the following description in order to fully understand the utility model, but originally
Utility model can also be implemented using other than the one described here other way, and those skilled in the art can not disobey
Similar popularization is done in the case where back the utility model connotation, therefore the utility model is not by the limit of following public specific embodiment
System.
A kind of packaging system of Couteat of Folic Acid disclosed in the present embodiment, comprising: surface sterilization device, meausring apparatus, purified water
Unit, unit with slurry, the unit, pelletization unit, drying unit, total mix unit, pelletizing unit, inner packing unit, outer of pulverizing and sieving
Packaging unit.
Surface sterilization device includes first surface disinfection unit, second surface disinfection unit, third surface sterilization unit,
Four surface sterilization units and the 5th surface sterilization unit, respectively to raw material folic acid, cornstarch, glucose, magnesium stearate
Surface sterilization is carried out with inner packaging material.Meausring apparatus include the first weighing unit, the second weighing unit, third weighing unit,
4th weighing unit, respectively to weigh raw material folic acid, cornstarch, glucose, magnesium stearate.The unit that pulverizes and sieves includes one
The sieve of a efficient universal pulverizer, the efficient universal pulverizer is 100 mesh screens, to be crushed and be sieved to glucose
Point.First surface disinfection unit is connected with the first weighing unit, and second surface disinfection unit is connected with the second weighing unit, third
Surface sterilization unit is connected by pulverizing and sieving unit with third weighing unit, the 4th surface sterilization unit and the 4th weighing unit
It is connected.Surface sterilization device is preferably pass-through box, which is arranged ultraviolet emission device.Wherein, guaranteeing surface sterilization
In the case that unit and weighing unit corresponding relationship are constant, the pass-through box of the first-the four surface sterilization unit be may be used interchangeably,
The same pass-through box can also be gradually used in conjunction with.
In the production of the present embodiment, raw material folic acid, cornstarch, glucose, magnesium stearate and inner packaging material are de- outer
After packaging, dust proof workshop is come into through pass-through box ultraviolet irradiation 30min.The glucose of no less than formula ratio is crossed efficient universal to crush
100 mesh screen of machine crushes, spare.Operator weighs folic acid, glucose, magnesium stearate, cornstarch by batch production expense,
The container of load weighted material cleaning or material bag are contained, sealing, and in container containing or the significant position of material bag outer layer
It sets and sticks material label, it is spare.
Water unit is purified, to produce purified water.Unit with slurry is to use purified water preparation by folic acid and cornstarch
Stir the bonding slurries formed.It includes efficient wet mixer-granulator that pelletization unit, which is used, and glucose, cornstarch are mixed,
And bonding slurries are added and are mixed and made into softwood, further include oscillating granulator, 24 mesh nylon mesh are installed on the oscillating granulator, it will
Wet granular is made in softwood.Drying unit carries out whole grain to dry wet particle, and to the particle after drying.First weighing unit and
Second weighing unit is connected with unit with slurry, and unit with slurry is connected with pelletization unit, and third weighing unit is connected with pelletization unit,
Second weighing unit is connected with pelletization unit;Pelletization unit is connected with drying unit.
In the production of the present embodiment, the first weighing unit and the second weighing unit weigh folic acid (0.0185kg), corn
Starch (0.197kg) is added unit with slurry and adds boiling purified water after addition purified water (0.226kg) stirs into suspension shape
(2.037kg), stirs into paste, and slurries are made, spare.Recipe quantity is weighed by the second weighing unit and third weighing unit again
Cornstarch (4.063 kg), glucose (4.117 kg) be placed in efficient wet mixer-granulator, unlatching be stirred 5 points
Clock is added slurries low speed and stirs cutting softwood 1~3 minute, pelletized on oscillating granulator with 24 mesh nylon mesh.It is wet by what is made
Particle is put into heated-air circulation oven, and set temperature is 55 DEG C, and starting device records time started and temperature (temperature requirement control
System within 55 ± 5 DEG C), every 15 minutes turning over materials are primary, and record temperature, be dried to particle drying weightlessness 7%-9% it
Between, record end time, drying terminates, and particle is taken out, with 24 mesh nylon screen whole grains.
Total mix unit includes Mixers with Multi-direction Movement, is mixed the particle for passing through whole grain to be added in magnesium stearate.Pressure
Blade unit includes rotary tablet machine, mixed granulation processing is formed tablet.Inner packing unit includes double aluminium
Foilpac machine, to pack the tablet for passing through tabletting using inner packaging material.Outer packing unit is to will be through inner packing
The tablet of material packaging carries out double aluminium packagings.Drying unit and the 4th weighing unit are connected with total mix unit;Total mix unit with
Pelletizing unit is connected, and pelletizing unit is connected with inner packing unit, and inner packing unit is additionally coupled to the 5th surface sterilization unit.Interior packet
Dress unit is connect with outer packing unit.
In the production of the present embodiment, the 4th weighing unit weighs the magnesium stearate (0.004kg) of recipe quantity, by qualified
The magnesium stearate of recipe quantity is added in grain, is placed on Mixers with Multi-direction Movement and carries out total mix, incorporation time 5 minutes, total mix terminated.
Then compressing tablet process is carried out to the particle Jing Guo total mix.Particle is added in hopper, first regulates loading, then
Tablet press machine pressure, tabletting speed are adjusted, equipment is opened and starts pressure testing piece, detect tablet weight variation, takes the circumstances into consideration to adjust according to testing result
Loading, tabletting speed, tablet press machine pressure are until whole qualifications can start formal tabletting.Operator is switched on every time, terminates
20 labels are continuously picked up from tablet press machine slice when the parameters such as preceding half an hour, midway adjustment pressure, speed, check every piece
Weight, and piece appearance check at any time (unilateral appearance answers smooth, no sliver, scarce side, sticking, loose pieces, color spot).Machine is normally transported
During turning, every 20 minutes inspection slice weights, it is ensured that lay particular stress on range.
Then dress is wrapped inside to the tablet Jing Guo tabletting and outer packing is handled.The medicine bottle of inner packing passes through the 5th surface
Disinfection unit disinfection treatment, the tablet bottling packing that will be crossed by compressing tablet process, it is bottled during every bottle cross and claim, content
In the 102%-105% of theoretical loading amount, and bottle appearance check at any time, complete inner packing.The tablet of bottled completion uses double aluminium machines
Double aluminium packagings are carried out, outer packing is completed.
The present embodiment is during producing Couteat of Folic Acid, each link compact layout, is connected compact, is conducive to production efficiency
Improve the reduction with production cost.
In order to adapt to interruption production, and accurate measurement intermediate link after total mix, particle is placed in clean in production
It is labelled after capping is sealed in the material barrel of net liner two layers of polyethylene polybag, it weighs, hands over intermediate station storage, calculate and receive
Rate.When carrying out compressing tablet process to the particle Jing Guo total mix, this batch particle to be produced need to be got from intermediate station.Tabletting terminates
Afterwards, surplus material, the unqualified label in tablet press machine turntable, feeder are collected together into small material bag, tightens sack, does
Material mark is scrapped well.Qualified label is weighed, and indicates the name of an article, batch number, barrel number, net weight, operator, date etc., it hands over
Intermediate station storage, calculated yield.When dress processing is wrapped inside to the tablet Jing Guo tabletting, it need to get this batch to be given birth to from intermediate station
The tablet that the compressing tablet process of production is crossed.After the completion of bottling, the tablet of inner packing processing is received with clean material basin, and in material basin
It is upper labelled, intermediate station is delivered, inbound formality, calculated yield are handled.When carrying out double aluminium packagings, this batch of institute is got from intermediate station
The medicine bottle handled through inner packing to be produced carries out double aluminium using double aluminium machines and packs, clears out a gathering place as required after production, and do and remember
Record.
Obviously, described embodiment is only a part of the embodiment of the utility model, instead of all the embodiments.
Based on the embodiments of the present invention, obtained by those of ordinary skill in the art without making creative efforts
Every other embodiment, fall within the protection scope of the utility model.
Claims (8)
1. a kind of packaging system of Couteat of Folic Acid characterized by comprising
Surface sterilization device, the surface sterilization device include first surface disinfection unit, second surface disinfection unit, third surface
Disinfection unit, the 4th surface sterilization unit and the 5th surface sterilization unit, respectively to raw material folic acid, cornstarch, grape
Sugar, magnesium stearate and inner packaging material carry out surface sterilization;
Meausring apparatus, the meausring apparatus include the first weighing unit, the second weighing unit, third weighing unit, the 4th weighing list
Member, respectively to weigh raw material folic acid, cornstarch, glucose, magnesium stearate;
Water unit is purified, to produce purified water;
Unit with slurry, to use purified water preparation to stir the bonding slurries formed by folic acid and cornstarch;
Unit is pulverized and sieved, to be crushed and be sieved to glucose;
Pelletization unit to by glucose, cornstarch mixing, and is added bonding slurries and is mixed and made into softwood, and by softwood system
At wet granular;
Drying unit carries out whole grain to dry wet particle, and to the particle after drying;
Total mix unit is mixed the particle for passing through whole grain to be added in magnesium stearate;
Pelletizing unit, mixed granulation processing is formed tablet;
Inner packing unit, to pack the tablet for passing through tabletting using inner packaging material;
Outer packing unit, the tablet will pack through inner packaging material carry out double aluminium packagings;
Wherein, the first surface disinfection unit is connected with the first weighing unit, and the second surface disinfection unit and second claims
It measures unit to be connected, the third surface sterilization unit is connected by pulverizing and sieving unit with third weighing unit, the 4th table
Face disinfection unit is connected with the 4th weighing unit;
First weighing unit and the second weighing unit are connected with unit with slurry, and the unit with slurry is connected with pelletization unit,
The third weighing unit is connected with pelletization unit, and second weighing unit is connected with pelletization unit;
The pelletization unit is connected with drying unit, and the drying unit is connected with total mix unit, the 4th weighing unit with
Total mix unit is connected;
The total mix unit is connected with pelletizing unit, and the pelletizing unit is connected with inner packing unit, the inner packing unit with
Outer packing unit is connected;
The unit with slurry is also connect with purifying water unit;
The inner packing unit is also connect with the 5th surface sterilization unit.
2. a kind of packaging system of Couteat of Folic Acid according to claim 1, which is characterized in that the surface sterilization device is to pass
Window is passed, which is arranged ultraviolet emission device.
3. a kind of packaging system of Couteat of Folic Acid according to claim 1, which is characterized in that the unit that pulverizes and sieves includes
Efficient universal pulverizer, the sieve of the efficient universal pulverizer are 100 mesh screens.
4. a kind of packaging system of Couteat of Folic Acid according to claim 1, which is characterized in that the pelletization unit includes efficient
Wet mixing pelletizer, oscillating granulator, and 24 mesh nylon mesh are installed on the oscillating granulator.
5. a kind of packaging system of Couteat of Folic Acid according to claim 1, which is characterized in that the drying unit include to
The heated-air circulation oven of dry wet particle, the 24 mesh nylon screens to carry out whole grain to the particle after drying.
6. according to a kind of packaging system of Couteat of Folic Acid described in claim 1, which is characterized in that the total mix unit includes multidirectional fortune
Dynamic mixing machine.
7. according to a kind of packaging system of Couteat of Folic Acid described in claim 1, which is characterized in that the pelletizing unit includes rotary
Tablet press machine.
8. according to a kind of packaging system of Couteat of Folic Acid described in claim 1, which is characterized in that the outer packing unit includes double aluminium
Foilpac machine.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN201820861920.6U CN208292136U (en) | 2018-06-05 | 2018-06-05 | A kind of packaging system of Couteat of Folic Acid |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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CN201820861920.6U CN208292136U (en) | 2018-06-05 | 2018-06-05 | A kind of packaging system of Couteat of Folic Acid |
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CN208292136U true CN208292136U (en) | 2018-12-28 |
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CN201820861920.6U Active CN208292136U (en) | 2018-06-05 | 2018-06-05 | A kind of packaging system of Couteat of Folic Acid |
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2018
- 2018-06-05 CN CN201820861920.6U patent/CN208292136U/en active Active
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