CN208218735U - One kind being synthetically prepared the efficient purifying plant of 2- thiophene acetic acid recrystallization method - Google Patents
One kind being synthetically prepared the efficient purifying plant of 2- thiophene acetic acid recrystallization method Download PDFInfo
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- CN208218735U CN208218735U CN201721612226.2U CN201721612226U CN208218735U CN 208218735 U CN208218735 U CN 208218735U CN 201721612226 U CN201721612226 U CN 201721612226U CN 208218735 U CN208218735 U CN 208218735U
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Abstract
The utility model discloses one kind to be synthetically prepared the efficient purifying plant of 2- thiophene acetic acid recrystallization method, including cold air tank, air compressor, valve, air inlet pipe, escape pipe, belt wheel, belt, the first motor, stirring rod, fin, thermal insulation layer, the first thermometer boss, reaction kettle, steam inlet, the first water pumper, outlet pipe, second temperature meter interface, the first water inlet pipe, the second motor, turntable, inner cylinder, outer cylinder, water storage box, the second water pumper, aqueduct, the second water inlet pipe, feed inlet, locating slot, convex block and groove.The beneficial effects of the utility model are: can more comprehensively monitor the temperature inside reaction kettle by the first thermometer boss and second temperature meter interface, and then convenient for the temperature inside the accurate solution reaction kettle of worker, and then crystallized in reaction kettle convenient for 2- thiophene acetic acid；It can quickly be cooled down to reaction kettle by the way that cold air tank is arranged, and then accelerate the speed that 2- thiophene acetic acid crystallizes in reaction kettle.
Description
Technical field
The utility model relates to a kind of purifying plant, it is efficient to be synthetically prepared 2- thiophene acetic acid recrystallization method for specially one kind
Purifying plant belongs to pharmaceutical production application field.
Background technique
2- thiophene acetic acid is the pharmaceutical intermediates such as cefaloridine, Cephalothin Sodium, therefore is widely used in medical field, and
Pharmaceutical factory is generally produced using water recrystallization method when producing 2- thiophene acetic acid, i.e., mixed 2- thiophene acetic acid crude product with water, so
After be heated to 60 degrees Celsius after naturally cool to 50 degrees Celsius and separate water layer, water layer is cooled to room temperature, and then white is precipitated in ice bath
Flat crystal obtains 2- thiophene acetic acid crystal after filtering.
But there are still certain defect, existing purifying plants one when in use for existing 2- thiophene acetic acid purifying plant
As using ice bath method to mixed solution cool down, and then cannot to mixed solution uniform decrease in temperature, meanwhile, filter device there is also
Filter efficiency it is too low and the shortcomings that small pieces crystalline solid is easy to run off.
Utility model content
The purpose of this utility model is that above-mentioned solution is unable to uniform decrease in temperature and small pieces crystalline solid is easy to run off in order to solve
The problem of and one kind is provided and is synthetically prepared the efficient purifying plant of 2- thiophene acetic acid recrystallization method.
The utility model is achieved through the following technical solutions above-mentioned purpose, and one kind is synthetically prepared-and thiophene acetic acid is with tying again
The efficient purifying plant of crystallization, including reaction kettle, are arranged escape pipe at the top of the reaction kettle, the reactor bottom be arranged steam into
Mouthful, the steam inlet side is arranged outlet pipe, and the reaction kettle side wall installs the first thermometer boss, inside the reaction kettle
Stirring rod is set, and the stirring rod side wall installs fin, and feed inlet, setting below the feed inlet is arranged in the reaction kettle side wall
Second temperature meter interface, described stirring rod one end connect air inlet pipe, and the air inlet pipe side wall installs valve, described air inlet pipe one end
Air compressor is connected, cold air tank is arranged in the air compressor bottom, and belt wheel, the belt wheel one is arranged in the stirring rod side
Belt is installed in side, and the belt side connects the first motor, and described outlet pipe one end connects the first water pumper, and described first takes out
Water dispenser side connects the first water inlet pipe, and first water inlet pipe one end connects outer cylinder, and inner cylinder is arranged in the outer barrel, described interior
Turntable is arranged in cylinder bottom, and the second motor is installed in the turntable bottom, and water storage box, the water storage box top is arranged in the outer cylinder side
The second water pumper is installed in portion, and second water pumper one end connects aqueduct, and the second water inlet pipe, institute is arranged in the aqueduct side
Inner cylinder bottom setting locating slot is stated, convex block is installed at the top of the turntable, groove, the reaction kettle side wall is arranged in the convex block side
Thermal insulation layer is set.
Preferably, first thermometer boss and the second temperature meter interface are mounted on thermometer, and described the
One thermometer boss and the second temperature meter interface are distributed in the two sides of the reaction kettle, and first thermometer boss
Height is lower than the height of the second temperature meter interface.
Preferably, the side wall of the fin is equipped with aperture, and the stirring rod is hollow steel pipe, and the stirring rod and institute
It states and is connected between air inlet pipe in dynamic sealing.
Preferably, the locating slot of the inner cylinder bottom setting is matched with the convex block at the top of the turntable, and
Pass through axis connection between second motor and the turntable.
Preferably, in close connection between first water inlet pipe and the outer cylinder, and first water inlet pipe is located at institute
State the surface of inner cylinder.
Preferably, connected between first motor and the belt wheel by the belt, and the belt wheel with it is described
It is in be fixedly connected between stirring rod.
Compared with prior art, the utility model has the beneficial effects that
1, the temperature inside reaction kettle can be more comprehensively monitored by the first thermometer boss and second temperature meter interface
Degree, and then convenient for the temperature inside the accurate solution reaction kettle of worker, and then crystallized in reaction kettle convenient for 2- thiophene acetic acid.
2, it can quickly be cooled down to reaction kettle by the way that cold air tank is arranged, and then accelerate 2- thiophene acetic acid in reaction kettle
The speed of interior crystallization.
3, the 2- thiophene acetic acid after crystallization can be made to be separated from water by the way that inner barrel and outer barrel is arranged, and then convenient for collecting 2- thiophene
Pheno acetic acid, meanwhile, the water energy after separation can be reached into recycling and reusing by the way that water storage box is arranged, and then be conducive to save water money
Source.
Detailed description of the invention
Fig. 1 is the utility model overall structure diagram.
Fig. 2 is the utility model inner cylinder bottom substance schematic diagram.
Fig. 3 is the utility model turntable structure schematic diagram.
In figure: 1, cold air tank；2, air compressor；3, valve；4, air inlet pipe；5, escape pipe；6, belt wheel；7, belt；8,
First motor；9, stirring rod；10, fin；11, thermal insulation layer；12, the first thermometer boss；13, reaction kettle；14, steam into
Mouthful；15, the first water pumper；16, outlet pipe；17, second temperature meter interface；18, the first water inlet pipe；19, the second motor；20,
Turntable；21, inner cylinder；22, outer cylinder；23, water storage box；24, the second water pumper；25, aqueduct；26, the second water inlet pipe；27, it feeds
Mouthful；28, locating slot；29, convex block；30, groove.
Specific embodiment
The following will be combined with the drawings in the embodiments of the present invention, carries out the technical scheme in the embodiment of the utility model
Clearly and completely describe, it is clear that the described embodiments are only a part of the embodiments of the utility model, rather than whole
Embodiment.Based on the embodiments of the present invention, those of ordinary skill in the art are without making creative work
Every other embodiment obtained, fall within the protection scope of the utility model.
Embodiment 1
It please refers to shown in Fig. 1-3, one kind being synthetically prepared the efficient purifying plant of 2- thiophene acetic acid recrystallization method, including reaction
Kettle 13, escape pipe 5 is arranged at the top of reaction kettle 13, and 13 bottom of reaction kettle is arranged steam inlet 14, can be made by steam inlet 14
The high steam of temperature heats mixed liquor, and outlet pipe 16,13 side wall of reaction kettle installation first is arranged in 14 side of steam inlet
Thermometer boss 12, is arranged stirring rod 9 inside reaction kettle 13, and 9 side wall of stirring rod installs fin 10,13 side wall of reaction kettle be arranged into
Material mouth 27, second temperature meter interface 17 is arranged below feed inlet 27, and 9 one end of stirring rod connects air inlet pipe 4,4 side wall of air inlet pipe peace
Valve 3 is filled, 4 one end of air inlet pipe connects air compressor 2, and cold air tank 1, the setting of 9 side of stirring rod is arranged in 2 bottom of air compressor
Belt 7 is installed in belt wheel 6,6 side of belt wheel, and 7 side of belt connects the first motor 8, and 16 one end of outlet pipe connects the first water pumper
15,15 side of the first water pumper connects the first water inlet pipe 18, and 18 one end of the first water inlet pipe connects outer cylinder 22, is arranged inside outer cylinder 22
Inner cylinder 21,21 side of inner cylinder are equipped with filter opening, and turntable 20 is arranged in 21 bottom of inner cylinder, and the second motor 19 is installed in 20 bottom of turntable, in turn
Enable the second motor 19 by driving turntable 20 to rotate, drives inner cylinder 21 to rotate, water storage box 23 is arranged in 22 side of outer cylinder, stores
Second water pumper 24 is installed, 24 one end of the second water pumper connects aqueduct 25,25 side of aqueduct setting second at the top of water tank 23
Water inlet pipe 26,21 bottom of inner cylinder are arranged locating slot 28, convex block 29 are installed at the top of turntable 20, and groove 30 is arranged in 29 side of convex block, into
And make to be stably mounted in inner cylinder 21 on turntable 20, and then prevent turntable 20 rotate when inner cylinder 21 will not as turntable 20 rotates,
Thermal insulation layer 11 is arranged in 13 side wall of reaction kettle, and then prevents ambient temperature from influencing the temperature in reaction kettle 13.
Embodiment 2
Please continue to refer to Fig. 1-3, the difference from embodiment 1 is that: the first thermometer boss 12 and second temperature meter interface
17 are mounted on thermometer, and then are convenient for measuring the temperature inside reaction kettle 13, and the first thermometer boss 12 and second temperature
Meter interface 17 is distributed in the two sides of reaction kettle 13, and the height of the first thermometer boss 12 is lower than the height of second temperature meter interface 17
Degree, and then the temperature inside the solution reaction kettle 13 that kept the producer comprehensive.The side wall of fin 10 is equipped with aperture, i.e. air inlet pipe
Cold air in 4 enters in mixed solution from fin 10, and stirring rod 9 is hollow steel pipe, and between stirring rod 9 and air inlet pipe 4
It is connected in dynamic sealing, and then makes stirring rod 9 in the course of rotation, the cold air inside air inlet pipe 4 is able to enter in stirring rod 9.
The locating slot 28 of 21 bottom of inner cylinder setting is matched with the convex block 29 at 20 top of turntable, and between the second motor 19 and turntable 20
By axis connection, and then the second motor 19 is set to be able to drive the rotation of inner cylinder 21, and then enable inner cylinder 21 by crystal and moisture
From.In close connection between first water inlet pipe 18 and outer cylinder 22, and the first water inlet pipe 18 is located at the surface of inner cylinder 21, and then makes
Mixed solution is able to enter inner cylinder 21, and flows out water from the filter opening of 21 side wall of inner cylinder.First motor 8 and belt wheel 6 it
Between connected by belt 7, and in being fixedly connected between belt wheel 6 and stirring rod 9.
When the utility model is used, passing through firstly, pour into 2- thiophene acetic acid in reaction kettle 13 by feed inlet 27
Two water inlet pipes 26 pour into water in reaction kettle 13, and steam is imported reaction kettle 13 by steam inlet 14, opens simultaneously the first electricity
The switch of motivation 8, and then rotate stirring rod 9, and then mixed solution is made to rise to 60 degrees Celsius, pass through the first thermometer boss
12 and second temperature meter interface 17 can measure the whole temperature of reaction kettle 13, then will be in cold air tank 1 by air compressor 2
Cold air by entering in reaction kettle 13 after air inlet pipe 4 and stirring rod 9, and then enable cold air with the rotation of stirring rod 9 and
Rotation, so enable cold air be uniformly mixed with solution after crystal is precipitated completely through the first water pumper 15 solid-liquid is mixed it is molten
Liquid is poured into inner cylinder 21, drives turntable 20 to rotate by the second motor 19, and then inner cylinder 21 is driven to rotate, and then make water from interior
The filter opening outflow of 21 side walls of cylinder, while crystal is kept in inner cylinder 21, water and crystal small in size enter water storage box 23 and then pass through
Second water pumper 24 enters water and mixed liquor with small size crystal in reaction kettle 13 by aqueduct 25, and then allows the water to
Enough to re-use, small size crystal incorporates in water again, so as to bear biggish crystal, then takes out inner cylinder 21, passes through
Internal crystal recycling.
It is obvious to a person skilled in the art that the present invention is not limited to the details of the above exemplary embodiments, and
And without departing substantially from the spirit or essential attributes of the utility model, it can realize that this is practical new in other specific forms
Type.Therefore, in all respects, the present embodiments are to be considered as illustrative and not restrictive, this is practical new
The range of type is indicated by the appended claims rather than the foregoing description, it is intended that containing for the equivalent requirements of the claims will be fallen in
All changes in justice and range are embraced therein.It should not treat any reference in the claims as limiting
Related claim.
In addition, it should be understood that although this specification is described in terms of embodiments, but not each embodiment is only wrapped
Containing an independent technical solution, this description of the specification is merely for the sake of clarity, and those skilled in the art should
It considers the specification as a whole, the technical solutions in the various embodiments may also be suitably combined, forms those skilled in the art
The other embodiments being understood that.
Claims (6)
1. one kind is synthetically prepared the efficient purifying plant of 2- thiophene acetic acid recrystallization method, including reaction kettle (13), it is characterised in that:
Escape pipe (5) are set at the top of the reaction kettle (13), steam inlet (14) are arranged in reaction kettle (13) bottom, the steam into
Mouth (14) side setting outlet pipe (16), reaction kettle (13) side wall install the first thermometer boss (12), the reaction kettle
(13) internal that stirring rod (9) are arranged, stirring rod (9) side wall installs fin (10), reaction kettle (13) side wall be arranged into
Second temperature meter interface (17) are arranged in material mouth (27), feed inlet (27) lower section, and described stirring rod (9) one end connects air inlet pipe
(4), air inlet pipe (4) side wall installation valve (3), described air inlet pipe (4) one end connect air compressor (2), the air
Cold air tank (1) is arranged in compressor (2) bottom, and belt wheel (6) are arranged in stirring rod (9) side, and skin is installed in belt wheel (6) side
Band (7), belt (7) side connect the first motor (8), and described outlet pipe (16) one end connects the first water pumper (15),
First water pumper (15) side connects the first water inlet pipe (18), and described first water inlet pipe (18) one end connects outer cylinder (22),
Inner cylinder (21) are set inside the outer cylinder (22), turntable (20) are arranged in inner cylinder (21) bottom, turntable (20) the bottom peace
It fills the second motor (19), water storage box (23) are arranged in outer cylinder (22) side, and installation second is taken out at the top of the water storage box (23)
Water dispenser (24), described second water pumper (24) one end connect aqueduct (25), second water inlet of aqueduct (25) side setting
It manages (26), locating slot (28) are arranged in inner cylinder (21) bottom, install convex block (29) at the top of the turntable (20), the convex block
(29) thermal insulation layer (11) are arranged in side setting groove (30), reaction kettle (13) side wall.
2. one kind according to claim 1 is synthetically prepared the efficient purifying plant of 2- thiophene acetic acid recrystallization method, feature
Be: first thermometer boss (12) and the second temperature meter interface (17) are mounted on thermometer, and described first
Thermometer boss (12) and the second temperature meter interface (17) are distributed in the two sides of the reaction kettle (13), and first temperature
The height of degree meter interface (12) is lower than the height of the second temperature meter interface (17).
3. one kind according to claim 1 is synthetically prepared the efficient purifying plant of 2- thiophene acetic acid recrystallization method, feature
Be: the side wall of the fin (10) is equipped with aperture, and the stirring rod (9) is hollow steel pipe, and the stirring rod (9) and institute
It states and is connected between air inlet pipe (4) in dynamic sealing.
4. one kind according to claim 1 is synthetically prepared the efficient purifying plant of 2- thiophene acetic acid recrystallization method, feature
Be: the locating slot (28) and the convex block (29) at the top of the turntable (20) of inner cylinder (21) the bottom setting match
It closes, and passes through axis connection between second motor (19) and the turntable (20).
5. one kind according to claim 1 is synthetically prepared the efficient purifying plant of 2- thiophene acetic acid recrystallization method, feature
It is: is in closely to connect, and first water inlet pipe (18) is located between first water inlet pipe (18) and the outer cylinder (22)
The surface of the inner cylinder (21).
6. one kind according to claim 1 is synthetically prepared the efficient purifying plant of 2- thiophene acetic acid recrystallization method, feature
It is: is connect between first motor (8) and the belt wheel (6) by the belt (7), and the belt wheel (6) and institute
State is in be fixedly connected between stirring rod (9).
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201721612226.2U CN208218735U (en) | 2017-11-28 | 2017-11-28 | One kind being synthetically prepared the efficient purifying plant of 2- thiophene acetic acid recrystallization method |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201721612226.2U CN208218735U (en) | 2017-11-28 | 2017-11-28 | One kind being synthetically prepared the efficient purifying plant of 2- thiophene acetic acid recrystallization method |
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| CN208218735U true CN208218735U (en) | 2018-12-11 |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112480067A (en) * | 2020-12-10 | 2021-03-12 | 武汉至精诚医药技术有限公司 | Method and device for producing thiophene and derivative thereof |
| CN113181679A (en) * | 2021-04-20 | 2021-07-30 | 金溪华香香料有限公司 | Recrystallization purification device of linalyl acetate |
| CN114210085A (en) * | 2021-02-04 | 2022-03-22 | 青岛智库生物技术有限公司 | Long-chain dicarboxylic acid refining plant |
-
2017
- 2017-11-28 CN CN201721612226.2U patent/CN208218735U/en active Active
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112480067A (en) * | 2020-12-10 | 2021-03-12 | 武汉至精诚医药技术有限公司 | Method and device for producing thiophene and derivative thereof |
| CN114210085A (en) * | 2021-02-04 | 2022-03-22 | 青岛智库生物技术有限公司 | Long-chain dicarboxylic acid refining plant |
| CN113181679A (en) * | 2021-04-20 | 2021-07-30 | 金溪华香香料有限公司 | Recrystallization purification device of linalyl acetate |
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