CN208140716U - A kind of novel agent box with paramagnetic particle method detection human IgG antibody - Google Patents
A kind of novel agent box with paramagnetic particle method detection human IgG antibody Download PDFInfo
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- CN208140716U CN208140716U CN201820620827.6U CN201820620827U CN208140716U CN 208140716 U CN208140716 U CN 208140716U CN 201820620827 U CN201820620827 U CN 201820620827U CN 208140716 U CN208140716 U CN 208140716U
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Abstract
The utility model relates to technical field of medical equipment, and a kind of novel agent box with paramagnetic particle method detection human IgG antibody is disclosed, including kit, the side of the kit is movably installed with storage room, grooved hole is opened up in the storage room, the side of the storage room is fixedly installed with connecting rod, and one end of the connecting rod runs through kit and extends to the inside of kit.Novel human IgG antibody's detection kit, pass through the cooperation of lid and swivel bearing, prevent reaction tube from skidding off outside reaction chamber, utilize the cooperation of apparatus for feeding and catch bar, so that the medicament of reaction is by discharge nozzle into reaction tube, sufficiently reaction, it is different according to the size of reaction tube using the cooperation of pedestal and compressed spring, adjust the depth of reaction chamber, cooperated using two position limiting clamps, preventing kit, reaction tube is fallen in the handling process, causes to detect sample damage, using the effect of locating piece, prevent extension rod from directly popping up the outside of cylinder.
Description
Technical field
It is specially a kind of to detect the novel of human IgG antibody with paramagnetic particle method the utility model relates to technical field of medical equipment
Kit.
Background technique
For holding the box of the chemical reagent such as detection chemical component, medicament residue, viral species, general hospital, pharmacy
Enterprise uses.
Currently, general Antigen of human blood group detection is mostly salt water law and column agglutination, centrifugation apparatus is required, time-consuming,
When for IgG class antibody test, need secondary antibody auxiliary that could observe as a result, kit can be anti-with a variety of blood groups of dispensable mould detection
Original, easy to operate, it is convenient to provide for clinical detection, existing most kit, in the detection process, due to moving reagent
Box causes the reaction tube in kit to fall, and leads to the sample damage of reaction, influences the efficiency of detection, while detecting sample
When quantity is excessive, need to also test tube be being looked for, waste the efficiency of detection.
Utility model content
(1) the technical issues of solving
In view of the deficiencies of the prior art, the utility model provides a kind of novel examination with paramagnetic particle method detection human IgG antibody
Agent box, has the advantages that good fixing effect, easy to detect, solves most kit, in the detection process, due to moving
Kit causes the reaction tube in kit to fall, and leads to the sample damage of reaction, influences the efficiency of detection, detects simultaneously
When sample size is excessive, the problem of need to also looking for test tube, waste the efficiency of detection.
(2) technical solution
To realize above-mentioned good fixing effect, purpose easy to detect, the utility model is provided the following technical solutions：A kind of use
Paramagnetic particle method detects the novel agent box of human IgG antibody, including kit, the side of the kit are movably installed with storage room,
Grooved hole is opened up in the storage room, the side of the storage room is fixedly installed with connecting rod, and one end of the connecting rod is run through
Kit and the inside for extending to kit offer the limiting slot inside kit, the connection in the connecting rod
The bottom of bar is connected with support plate, and the side of the support plate is fixedly installed with the positioning positioned at kit inner cavity side
The inside fixing sleeve of cylinder, the positioning tube is equipped with adjustable spring, and one end of the adjustable spring is fixedly connected with limited block, described
One end of limited block runs through positioning tube and extends to the outside of positioning tube, and the side of the reaction chamber has positioned at kit table
The label in face, the side of the label are placed with the isolation board in the middle part of kit, and the side of the isolation board is placed with examination
Pipe support is fixedly installed with storage test tube on the rack for test tube, and fixing sleeve is equipped with reaction tube in the reaction chamber, and the reaction tries
The apparatus for feeding being fixedly installed at the top of kit above pipe, the top movable of the apparatus for feeding are set with promotion
One end of bar, the catch bar runs through apparatus for feeding and extends to the inside of apparatus for feeding, and the two sides of the apparatus for feeding are solid
Surely it is communicated with feed pipe, the bottom fixation of the apparatus for feeding is communicated with discharge nozzle, and one end of the discharge nozzle extends to reaction
The top of test tube is fixedly installed with the magnet positioned at reaction chamber intracavity bottom, the reaction tube below the reaction tube
Top movable be set with stirring rod, one end of the stirring rod is through reaction tube and extends to the inside of reaction tube, institute
It states and is placed with magnetic bead in reaction tube, the bottom of the reaction tube is movably installed with pedestal, the fixed peace in the top of the pedestal
Equipped with the position-limiting drum for being located at reaction chamber side.
Preferably, the position-limiting drum includes cylinder, and the bottom of the cylinder lumen is fixedly installed with extension spring, the drawing
The one end for stretching spring is fixedly connected with locating piece, and the side of the locating piece is fixedly connected with extension rod, and the one of the extension rod
End runs through cylinder and extends to the outside of cylinder, and one end of the extension rod is fixedly installed with the position limiting clamp outside cylinder.
Preferably, the top movable of the reaction tube is set with the lid at the top of reaction chamber, and the one of the lid
Hold fixing sleeve that swivel bearing is housed.
Preferably, the two sides of the pedestal and the inner wall of reaction chamber are mutually perpendicular to, the two sides of the pedestal and reaction chamber
Inner wall is flexibly connected, and the bottom of the pedestal is fixedly connected with compressed spring, and one end of the compressed spring is fixedly connected on instead
Answer the bottom of room.
Preferably, fixing sleeve is equipped with anti-slip layer on the position limiting clamp, and there are two the quantity of the position limiting clamp, and two limits
The symmetrical two sides for being distributed in reaction tube of folder.
Preferably, there are two the quantity of the connecting rod, one end and the kit of two connecting rods are mutually perpendicular to, and
The symmetrical two sides for being distributed in storage room of two connecting rods.
(3) beneficial effect
Compared with prior art, the utility model provides a kind of novel agent box with paramagnetic particle method detection human IgG antibody,
Has following beneficial effect：
1, the novel agent box passes through the cooperation of storage room and slot, and when placing heavy workload, the sample of detection is excessive, instead
Take an entrance examination it is effective it is complete need to also look for, the efficiency of detection is wasted, using the cooperation of limiting slot and limited block, so that storage room is fixed on examination
The inside of agent box, prevents storage room from skidding off out of kit, using the cooperation of support plate and connecting rod, prevents connecting rod in movement
When, it is shaken in kit, influences the stability of storage room, using the cooperation of label and isolation board, so that storage test tube and anti-
Test tube is answered convenient for distinguishing, prevents storage test tube and reaction tube chaotic.
2, the novel agent box prevents reaction tube from skidding off outside reaction chamber by the cooperation of lid and swivel bearing, utilizes
The cooperation of apparatus for feeding and catch bar sufficiently reacts so that the medicament of reaction passes through discharge nozzle into reaction tube, utilizes magnetic bead
With the effect of magnet so that absorption antibody do not allow to be easy to run off, using the cooperation of pedestal and compressed spring, according to reaction tube
Size is different, adjusts the depth of reaction chamber, is cooperated using two position limiting clamps, prevents kit in the handling process, reaction tube
It falls, detection sample damage is caused to prevent extension rod from directly popping up the outside of cylinder using the effect of locating piece.
Detailed description of the invention
FIG. 1 is a schematic structural view of the utility model；
Fig. 2 is the overlooking structure diagram of Fig. 1；
Fig. 3 is the side structure schematic view of Fig. 1；
Fig. 4 is the structural schematic diagram of reaction chamber；
Fig. 5 is the structural schematic diagram of position-limiting drum.
In figure：1 kit, 2 storage rooms, 3 slots, 4 connecting rods, 5 limiting slots, 6 support plates, 7 positioning tubes, 8 adjustable springs,
9 limited blocks, 10 reaction chambers, 11 labels, 12 isolation boards, 13 rack for test tubes, 14 storage test tubes, 15 reaction tubes, 16 swivel bearings, 17
Lid, 18 stirring rods, 19 magnetic beads, 20 pedestals, 21 compressed springs, 22 position-limiting drums, 221 cylinders, 222 extension springs, 223 positioning
Block, 224 extension rods, 225 position limiting clamps, 23 apparatuss for feeding, 24 catch bars, 25 feed pipes, 26 discharge nozzles, 27 magnet.
Specific embodiment
The following will be combined with the drawings in the embodiments of the present invention, carries out the technical scheme in the embodiment of the utility model
Clearly and completely describe, it is clear that the described embodiments are only a part of the embodiments of the utility model, rather than whole
Embodiment.Based on the embodiments of the present invention, those of ordinary skill in the art are without making creative work
Every other embodiment obtained, fall within the protection scope of the utility model.
Please refer to Fig. 1-5, a kind of novel agent box with paramagnetic particle method detection human IgG antibody, including kit 1, kit 1
Side be movably installed with storage room 2, grooved hole 3 is opened up in storage room 2, the side of storage room 2 is fixedly installed with connecting rod 4,
One end of connecting rod 4 runs through kit 1 and extends to the inside of kit 1, and there are two the quantity of connecting rod 4, two connecting rods 4
One end be mutually perpendicular to kit 1, and two sides for being distributed in storage room 2 that two connecting rods 4 are symmetrical prevent storage room
When 2 removal kits 1 are outer, connecting rod 4 is shaken back and forth in kit 1, influences the stability of storage room 2, causes storage room 2 sliding
The outside of kit 1 out prevents storage room 2 from skidding off the outside of kit 1 using the cooperation of limiting slot 5 and limited block 9, improves
The stability of storage room 2, the limiting slot 5 inside kit 1 is offered in connecting rod 4, and the bottom activity of connecting rod 4 connects
It is connected to support plate 6, the side of support plate 6 is fixedly installed with the positioning tube 7 positioned at 1 inner cavity side of kit, the inside of positioning tube 7
Fixing sleeve is equipped with adjustable spring 8, and one end of adjustable spring 8 is fixedly connected with limited block 9, and positioning tube 7 is run through in one end of limited block 9
And the outside of positioning tube 7 is extended to, there are the label 11 positioned at 1 surface of kit, the side of label 11 in the side of reaction chamber 10
Face is placed with the isolation board 12 positioned at 1 middle part of kit, and the side of isolation board 12 is placed with rack for test tube 13, convenient for storage test tube 14
It with the differentiation of reaction tube 15, prevents from storing test tube 14 and reaction tube 15 places confusion, convenient for differentiation storage test tube 14 and instead
Test tube 15 is answered, storage test tube 14 is fixedly installed on rack for test tube 13, fixing sleeve is equipped with reaction tube 15, reaction examination in reaction chamber 10
The top of pipe 15 is fixedly installed with the apparatus for feeding 23 positioned at 1 top of kit, and the top movable of apparatus for feeding 23, which is set with, to be pushed away
One end of lever 24, catch bar 24 runs through apparatus for feeding 23 and extends to the inside of apparatus for feeding 23, the two sides of apparatus for feeding 23
Fixed to be communicated with feed pipe 25, the bottom fixation of apparatus for feeding 23 is communicated with discharge nozzle 26, and one end of discharge nozzle 26 extends to
The top of reaction tube 15, the lower section of reaction tube 15 are fixedly installed with the magnet 27 positioned at 10 intracavity bottom of reaction chamber, reaction
The top movable of test tube 15 is set with stirring rod 18, and one end of stirring rod 18 through reaction tube 15 and extends to reaction tube 15
Inside, the top movable of reaction tube 15 is set with the lid 17 positioned at the top of reaction chamber 10, one end fixing sleeve of lid 17
Equipped with swivel bearing 16, magnetic bead 19 is placed in reaction tube 15, the bottom of reaction tube 15 is movably installed with pedestal 20, pedestal
20 two sides and the inner wall of reaction chamber 10 are mutually perpendicular to, and the two sides of pedestal 20 are flexibly connected with the inner wall of reaction chamber 10, pedestal 20
Bottom be fixedly connected with compressed spring 21, one end of compressed spring 21 is fixedly connected on the bottom of reaction chamber 10, prevents from reacting
The length of test tube 15 is different, causes reaction tube 15 not to be put into the inside of reaction chamber 10, bottom plate 20 is according to different size of anti-
Test tube 15 is answered to adjust the depth of reaction chamber 10,21 springing pedestal 20 of compressed spring returns to when reactionless test tube 15 on bottom plate 20
Position originally, improves the utilization rate of bottom plate 20, and the top of pedestal 20 is fixedly installed with the limit positioned at 10 side of reaction chamber
Cylinder 22, position-limiting drum 22 include cylinder 221, and the bottom of 221 inner cavity of cylinder is fixedly installed with extension spring 222, extension spring 222
One end is fixedly connected with locating piece 223, and the side of locating piece 223 is fixedly connected with extension rod 224, and one end of extension rod 224 is passed through
It wears cylinder 221 and extends to the outside of cylinder 221, one end of extension rod 224 is fixedly installed with the limit outside cylinder 221
Folder 225, fixing sleeve is equipped with anti-slip layer on position limiting clamp 225, prevents reaction tube 15, and in the handling process, reaction tube 15 is from anti-
It answers and is skidded off in room 10, cause reaction tube 15 broken, influence the efficiency of pattern detection, there are two the quantity of position limiting clamp 225, and two
The symmetrical two sides for being distributed in reaction tube 15 of a position limiting clamp 225, improve the stability of reaction tube 15.
When work, reaction tube 15 is put into reaction chamber 10, and 222 springing extension rod 224 of extension spring is mobile, extension rod
224 drive position limiting clamp 225 to clamp reaction tube 15, are put into sample to reaction tube 15, press apparatus for feeding 23, make lysate
It is cracked in reaction tube 15, using the effect of centrifugation, medicament reacts in reaction tube 15, tries magnetic bead 19 to reaction is added
In pipe 15, so that IgG antibody is adsorbed on 19 surface of magnetic bead, using the adsorption capacity of magnet 27, so that IgG antibody is adsorbed on reaction examination
On the tube wall of pipe 15, the liquid after reacting is outwelled, eluent is added and is eluted out the IgG antibody adsorbed on magnetic bead 19, examined
After the completion of survey, reaction tube 15 is taken out, is put into storage test tube 14, labelled 11 to storage test tube 14 and reaction tube 15
Side pulls storage room 2 when heavy workload, and limited block 9 inwardly squeezes adjustable spring 8, takes out extra test tube and examined
It surveys.
In conclusion novel human IgG antibody's detection kit places work by the cooperation of storage room 2 and slot 3
When measuring big, the sample of detection is excessive, and reaction tube 15, which is finished, need to also look for, and wastes the efficiency of detection, utilizes limiting slot 5 and limit
The cooperation of block 9 prevents storage room 2 from skidding off out of kit 1, utilizes support so that storage room 2 is fixed on the inside of kit 1
The cooperation of plate 6 and connecting rod 4 prevents connecting rod 4 when moving, shakes in kit 1, influences the stability of storage room 2, benefit
Storage 14 He of test tube is prevented so that storage test tube 14 and reaction tube 15 are convenient for distinguishing with the cooperation of label 11 and isolation board 12
Reaction tube 15 is chaotic；It by the cooperation of lid 17 and swivel bearing 16, prevents reaction tube 15 from skidding off outside reaction chamber 10, utilizes
The cooperation of apparatus for feeding 23 and catch bar 24 is sufficiently reacted so that the medicament of reaction passes through discharge nozzle 26 into reaction tube 15,
It is different according to the size of reaction tube 15 using the cooperation of pedestal 20 and compressed spring 21, the depth of reaction chamber 10 is adjusted, is utilized
Two position limiting clamps 225 cooperate, and prevent kit 1 in the handling process, and reaction tube 15 is fallen, and cause to detect sample damage, benefit
With the effect of locating piece 223, the outside of the directly pop-up cylinder 221 of extension rod 224 is prevented；Solve most kit 1,
In detection process, due to moving kit 1, the reaction tube 15 in kit 1 is caused to fall, leads to the sample damage of reaction,
Influence detection efficiency, while detect sample size it is excessive when, the problem of need to also looking for test tube, waste the efficiency of detection.
It should be noted that, in this document, relational terms such as first and second and the like are used merely to a reality
Body or operation are distinguished with another entity or operation, are deposited without necessarily requiring or implying between these entities or operation
In any actual relationship or order or sequence.Moreover, the terms "include", "comprise" or its any other variant are intended to
Non-exclusive inclusion, so that the process, method, article or equipment including a series of elements is not only wanted including those
Element, but also including other elements that are not explicitly listed, or further include for this process, method, article or equipment
Intrinsic element.
While there has been shown and described that the embodiments of the present invention, for the ordinary skill in the art,
It is understood that these embodiments can be carried out with a variety of variations in the case where not departing from the principles of the present invention and spirit, repaired
Change, replacement and variant, the scope of the utility model is defined by the appended claims and the equivalents thereof.
Claims (6)
1. a kind of novel agent box with paramagnetic particle method detection human IgG antibody, including kit (1), it is characterised in that：The reagent
The side of box (1) is movably installed with storage room (2), is opened up grooved hole (3) on the storage room (2), the side of the storage room (2)
Face is fixedly installed with connecting rod (4), and one end of the connecting rod (4) through kit (1) and extends to the interior of kit (1)
Portion offers the limiting slot (5) internal positioned at kit (1), the bottom activity of the connecting rod (4) on the connecting rod (4)
It is connected with support plate (6), the side of the support plate (6) is fixedly installed with the positioning tube positioned at kit (1) inner cavity side
(7), the inside fixing sleeve of the positioning tube (7) is equipped with adjustable spring (8), and one end of the adjustable spring (8) is fixedly connected with
One end of limited block (9), the limited block (9) runs through positioning tube (7) and extends to the outside of positioning tube (7), the kit
(1) it is offered at the top of reaction chamber (10), the side of the reaction chamber (10) is equipped with the label positioned at kit (1) surface
(11), the side of the label (11) is placed with the isolation board (12) in the middle part of kit (1), the side of the isolation board (12)
Face is placed with rack for test tube (13), is fixedly installed on the rack for test tube (13) and is stored test tube (14), solid in the reaction chamber (10)
Surely it is set with reaction tube (15), the charging being fixedly installed with above the reaction tube (15) at the top of kit (1)
The top movable of equipment (23), the apparatus for feeding (23) is set with catch bar (24), and one end of the catch bar (24) is run through
Apparatus for feeding (23) and the inside for extending to apparatus for feeding (23), the fixation of the two sides of the apparatus for feeding (23) are communicated with charging
It manages (25), the bottom fixation of the apparatus for feeding (23) is communicated with discharge nozzle (26), and one end of the discharge nozzle (26) extends to
The top of reaction tube (15) is fixedly installed with the magnetic positioned at reaction chamber (10) intracavity bottom below the reaction tube (15)
The top movable of iron (27), the reaction tube (15) is set with stirring rod (18), and one end of the stirring rod (18) is through anti-
It answers test tube (15) and extends to the inside of reaction tube (15), be placed with magnetic bead (19) in the reaction tube (15), it is described anti-
It answers the bottom of test tube (15) to be movably installed with pedestal (20), is fixedly installed with above the pedestal (20) positioned at reaction chamber (10)
The position-limiting drum (22) of side.
2. a kind of novel agent box with paramagnetic particle method detection human IgG antibody according to claim 1, it is characterised in that：Institute
Stating position-limiting drum (22) includes cylinder (221), and the bottom of cylinder (221) inner cavity is fixedly installed with extension spring (222), described
One end of extension spring (222) is fixedly connected with locating piece (223), and the side of the locating piece (223) is fixedly connected with extension
One end of bar (224), the extension rod (224) runs through cylinder (221) and extends to the outside of cylinder (221), the extension rod
(224) one end is fixedly installed with the position limiting clamp (225) external positioned at cylinder (221).
3. a kind of novel agent box with paramagnetic particle method detection human IgG antibody according to claim 1, it is characterised in that：Institute
The top movable for stating reaction tube (15) is set with lid (17) at the top of reaction chamber (10), one end of the lid (17)
Fixing sleeve is equipped with swivel bearing (16).
4. a kind of novel agent box with paramagnetic particle method detection human IgG antibody according to claim 1, it is characterised in that：Institute
The inner wall of the two sides and reaction chamber (10) of stating pedestal (20) is mutually perpendicular to, and the two sides of the pedestal (20) are interior with reaction chamber (10)
Wall is flexibly connected, and the bottom of the pedestal (20) is fixedly connected with compressed spring (21), and one end of the compressed spring (21) is solid
Surely it is connected to the bottom of reaction chamber (10).
5. a kind of novel agent box with paramagnetic particle method detection human IgG antibody according to claim 2, it is characterised in that：Institute
It states fixing sleeve on position limiting clamp (225) and anti-slip layer is housed, there are two the quantity of the position limiting clamp (225), and two position limiting clamps (225)
The symmetrical two sides for being distributed in reaction tube (15).
6. a kind of novel agent box with paramagnetic particle method detection human IgG antibody according to claim 1, it is characterised in that：Institute
There are two the quantity for stating connecting rod (4), and one end and the kit (1) of two connecting rods (4) are mutually perpendicular to, and two connections
The symmetrical two sides for being distributed in storage room (2) of bar (4).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820620827.6U CN208140716U (en) | 2018-04-27 | 2018-04-27 | A kind of novel agent box with paramagnetic particle method detection human IgG antibody |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820620827.6U CN208140716U (en) | 2018-04-27 | 2018-04-27 | A kind of novel agent box with paramagnetic particle method detection human IgG antibody |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN208140716U true CN208140716U (en) | 2018-11-23 |
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ID=64310537
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201820620827.6U Active CN208140716U (en) | 2018-04-27 | 2018-04-27 | A kind of novel agent box with paramagnetic particle method detection human IgG antibody |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN208140716U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109514513A (en) * | 2019-01-17 | 2019-03-26 | 中国电建集团贵州电力设计研究院有限公司 | A kind of high efficiency electrode heat-preservation cylinder |
-
2018
- 2018-04-27 CN CN201820620827.6U patent/CN208140716U/en active Active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109514513A (en) * | 2019-01-17 | 2019-03-26 | 中国电建集团贵州电力设计研究院有限公司 | A kind of high efficiency electrode heat-preservation cylinder |
| CN109514513B (en) * | 2019-01-17 | 2023-11-07 | 中国电建集团贵州电力设计研究院有限公司 | Welding rod heat preservation cylinder |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CB03 | Change of inventor or designer information |
Inventor after: Wang Li Inventor after: Wang Sibo Inventor before: Wang Li |
|
| CB03 | Change of inventor or designer information | ||
| CP03 | Change of name, title or address |
Address after: No. 29, Xinye 7th Street, West District, Binhai New Area Economic and Technological Development Zone, Tianjin 300462 Patentee after: Tianjin Texiang Biotechnology Co.,Ltd. Address before: No. 29, Xinye 7th Street, West District, Tianjin Economic and Technological Development Zone, Binhai New Area, Tianjin 300000 Patentee before: TIANJIN DEXIANG BIOTECHNOLOGY Co.,Ltd. |
|
| CP03 | Change of name, title or address |