CN208076394U - A kind of optical waveguide biosensor sensor of low testing cost and temperature-insensitive - Google Patents
A kind of optical waveguide biosensor sensor of low testing cost and temperature-insensitive Download PDFInfo
- Publication number
- CN208076394U CN208076394U CN201820557790.7U CN201820557790U CN208076394U CN 208076394 U CN208076394 U CN 208076394U CN 201820557790 U CN201820557790 U CN 201820557790U CN 208076394 U CN208076394 U CN 208076394U
- Authority
- CN
- China
- Prior art keywords
- mzi
- loop
- micro
- temperature
- output end
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Abstract
A kind of optical waveguide biosensor sensor of low testing cost and temperature-insensitive, wideband light source including particular range of wavelengths, sense micro-loop, sensitive zones, sense the straight-through output end of micro-loop, sense the download output end of micro-loop, Mach increases Dare interferometer MZI, first output end of MZI, second output end of MZI, the detector A being connected with first output end of the MZI and detector B being connected with second output end of MZI, the wideband light source of the particular range of wavelengths is composed of the wavelength filter of common wide light source and required wave-length coverage, the wideband light source of the particular range of wavelengths is connected with the input terminal of sensing micro-loop, the download output end of the sensing micro-loop is connected with the input terminal of MZI, two output ends of MZI are connected with detector A and detector B respectively.The utility model has the characteristics that temperature-insensitive and low testing cost.
Description
Technical field
The utility model is related to optical waveguide biosensor sensing detection field, especially a kind of temperature-insensitive has low detection
The optical waveguide biosensor sensor of cost.
Background technology
Based on the optical waveguide sensor of toroidal cavity resonator (ring resonator), since there is high sensitivity, exempt from label
It detection, in real time monitoring, the advantages that sample consumption is low, not by electromagnetic interference, plays in chemistry and biological sample analysis
Very important role.In particular with high index-contrast platform (for example, silicon-on-insulator (SOI)
Platform, the silicon platform on insulator) the super-small micro-loop realized, since its technique and traditional cmos process are completely simultaneous
Hold, and be expected to realize on the same chip with the hybrid integrated of the devices such as semiconductor light source, detector and microfluidic control unit,
It is final to realize miniaturization, a portable multifunctional sensing detector.
However, since silicon materials have larger thermo-optical coeffecient (1.86 × 10-4/ K) so that the sensing based on silicon materials is micro-
Ring is very sensitive to the variation of environment temperature, and the drift of resonance wavelength can reach 50pm/ DEG C.So in sensing detection process
In, if minor change occurs in environment temperature, this all can be to the essence of sensing micro-loop testing result (the resonance wavelength variable quantity of micro-loop)
Exactness has an important influence on.In order to eliminate influence of the variation of ambient temperature to sensing micro-loop testing result, a kind of common method
It is exactly to use temperature controller (N.A.Yebo, et an al, " On-chip arrayed waveguide grating
interrogated silicon-on-insulator microring resonator-based gas sensor,”IEEE
Photon.Technol.Lett., vol.23, no.20, pp.1505-1507,2011), it may ensure that environment temperature exists always
One stationary temperature, but the method increase size, cost and the complexities etc. of sensing micro-loop detecting system, are unfavorable for big
Scale on piece is integrated.Another method is by additional device (D.-X.Xu, et al, " Real-time cancellation
of temperature induced resonance shifts in SOI wire waveguide ring resonator
Label-free biosensor arrays, " Opt.Express, vol.18, no.22, pp.22867-22879,2010), than
Such as variation of ambient temperature is monitored in real time using a reference rings, the result of reference rings is then utilized to believe from the detection of sensing micro-loop
Temperature is eliminated in number to be influenced, and this method needs additional data processing.
In addition, the test to sensing micro-loop mainly calculates detectable substance in micro-loop by monitoring the variation of its resonance wavelength
The case where.Since the resonance peak of micro-loop is more sharp, i.e. Q values are higher, this is allowed for peak wavelength position permanent normal need really
The detection of micro-ring sensor is significantly increased by the high-precision tunable laser in periphery either high-precision spectrometer
Cost is unfavorable for its application in portable sensor.In order to solve this problem, on piece spectrometer is used to monitoring micro-loop
Wavelength change situation, such as J.Zou et al. (J.Zou, Z.Le, and J.-J.He, " Temeprature self-
compensated optical waveguide biosensor based on cascade of ring resonator
and arrayed waveguide grating spectrometer,”J.Lightwave Technol.,34(21),
) and N.A.Yebo et al. (N.A.Yebo, et al, " On-chip arrayed waveguide pp.4856-4863,2016
grating interrogated silicon-on-insulator microring resonator-based gas
Sensor, " IEEE Photon.Technol.Lett., vol.23, no.20, pp.1505-1507,2011) propose utilize piece
Cascade array waveguide grating spectrometer is gone up to realize the measurement to sensing micro-ring resonant wavelength change.In this scenario due to needing
High-resolution array waveguide grating is wanted, causes such array waveguide grating size larger, it is also incomplete in technique at this stage
The device performance is less ideal in the case of maturation, also can accordingly decline to being accurate to for micro-ring resonant wavelength measurement.
Invention content
In order to solve the problems, such as that tradition senses the temperature sensitivity that micro-loop encounters in the detection and high expensive testing cost, to meet
Its demand in the sensing detection application of portable low cost, the utility model provides a kind of based on sensing micro-loop and Mach
Increase the cascade optical waveguide sensor of Dare interferometer, it has the characteristics that temperature-insensitive and low testing cost.
The purpose of this utility model is achieved by the following technical solution：
A kind of optical waveguide biosensor sensor of low testing cost and temperature-insensitive, includes the broadband light of particular range of wavelengths
Source, sensing micro-loop, sensitive zones, the straight-through output end for sensing micro-loop, the download output end for sensing micro-loop, Mach increase Dare interference
First output end of instrument MZI, MZI, second output end of MZI, the detector A being connected with first output end of MZI and
The detector B being connected with second output end of MZI, the wideband light source of the particular range of wavelengths is by common wide light source and institute
The wavelength filter of wave-length coverage is needed to be composed, the input terminal of the wideband light source and sensing micro-loop of the particular range of wavelengths
Be connected, the download output end of the sensing micro-loop is connected with the input terminal of MZI, two output ends of MZI respectively with spy
Device A is surveyed with detector B to be connected.
Further, the upper arm waveguide of the MZI is by two kinds of width w0And w1Composition, w0And w1Between pass through lossless taper
Waveguide connects；The underarm waveguide of MZI is by two kinds of width w0And w2Composition, w0And w2Between pass through lossless tapered transmission line and connect；
The upper underarm width of MZI is w0Waveguide between length difference be Δ L, width is w in upper underarm1And w2Waveguide length be La, and La
Meet relational expression L with Δ La=x × Δ L, wherein x are temperature dependency regulatory factor；Duct width w0、w1And w2And x is really
Surely to meet MZI with variation of ambient temperature wavelength shift and sensing micro-loop resonance wavelength in detectable substance with environment temperature
The wavelength shift of variation is identical, i.e. the two temperature dependency having the same.
Further, the waveguiding structure of the sensing micro-loop and MZI are bar shaped or ridge, and sense the sensing unit of micro-loop
Domain and with protection top covering MZI be in identical detection sample, i.e., detection sample cover sensitive zones and MZI, when
When sensing micro-loop and MZI temperature dependencies having the same, the duct width w of micro-loop is sensedsWith the duct width parameter w of MZI0、
w1And w2And meet following relational expression between x
Wherein λ0Initial resonant wavelength for the sensing micro-loop selected in design,WithIt is wide respectively
Degree is wsWhen sense micro-loop waveguide effective refractive index and group index,WithIt is respectively
Waveguide in MZI is w in widthiWhen corresponding effective refractive index and group index.
Further, the sensing micro-ring resonant wavelength is λs, the performance number I that obtains in detector AA(λs) and detection
The performance number I obtained in device BB(λs), define detection functionWork as λsTo include λ0MZI's inside
In the wave-length coverage of half of Free Spectral Range when variation, the cross-coupling coefficient k of the outbound course coupler of MZImSelection
Satisfaction makes R (λs) in the wave-length coverage and λsBetween have maximum linear relationship range.
The utility model is when carrying out the analysis of sensing detection object, it is assumed that the resonance of inductive sensing micro-loop when initial time t=0
Wavelength is λ0, detection function value is R (λ0), it is λ to the resonance wavelength of inductive sensing micro-loop in moment tt, detection function value is R
(λt), R (λ0) and R (λt) all it is always positioned at R (λs) linear relationship within the scope of.Simultaneously in determining cross-coupling coefficient kmUnder, R
(λs) linear relationship range size can change by adjusting the Free Spectral Range size of MZI.
When carrying out the analysis of sensing detection object, R (λ are utilizeds) and λsBetween linear relationship slope value, pass through t moment and t
The detection function value changes delta R (Δ R=R (λ at=0 momentt)-R(λ0)) resonance wave long value changes delta λ in sensing micro-loop is extrapolated,
Actually detected object is extrapolated further according to the relationship between the concentration variation and sensing micro-ring resonant wavelength change Δ λ of detection and analysis object
Situation of change.
The beneficial effects of the utility model are mainly manifested in：1, the testing cost to sensing micro-loop is reduced；2, sensing is solved
The temperature tender subject encountered in micro-loop detection；3, application of the micro-loop in miniaturization, portable sensing detection is realized；4, it
It can be realized in different material platforms, such as silicon nitride (Si3N4) and the platforms such as silicon (Si).
Description of the drawings
Fig. 1 be the utility model proposes a kind of low testing cost and temperature-insensitive optical waveguide biosensor sensor tool
Body embodiment structure schematic diagram；
Fig. 2 be the utility model proposes optical waveguide biosensor sensor structure in the regions MZI enlarged diagram；
Fig. 3 is the enlarged drawing of temperature dependency adjustment region in MZI；
Fig. 4 is the sectional view at AA ' in Fig. 1, i.e., the cross-sectional view of micro-loop waveguide is sensed in sensitive zones；
Fig. 5 is the sectional view at BB ' in Fig. 1, i.e. waveguide cross-section schematic diagram in MZI；
Fig. 6 be the utility model proposes optical waveguide sensor realize temperature-insensitive detection schematic diagram；
Fig. 7 is that the waveguide of sensing micro-loop corresponds to different waveguide width when highly for 250nm and aqueous solution as top covering
Under, the ability of TE basic modes and TM basic modes perception solution variations in refractive index in waveguide；
Fig. 8 be duct height be 250nm when sensing micro-loop resonance wavelength and MZI spectrum under different waveguide width
The duct width w selected in temperature dependency and below designs、w0、w1And w2；
Fig. 9 is the temperature dependency of MZI at 1550nm with the variation relation of x.
Figure 10 is the relationship for sensing the related correlation of the temperature of both the MZI of micro-loop to x=3.5 when with wavelength change
Figure；
Figure 11 is that the light intensity of two output port in the wave-length coverage of a Free Spectral Range of MZI becomes with wavelength
The schematic diagram of change；
Figure 12 (a) is the power ratio between two output port in the wave-length coverage of a Free Spectral Range of MZI
Natural logrithm value ρ with the schematic diagram of wavelength change, be (b) near the intermediate wavelength of (a) in a Free Spectral Range
Enlarged drawing；
Figure 13 is the outbound course coupler cross-coupling coefficient k in MZImIt takesWhen, sense the one way of micro-loop waveguide
Transmission loss a corresponding detection function R (λ when taking different values) with the resonance wavelength of sensing micro-loopsThe relational graph of variation；
Figure 14 is the one way Transmission loss a=0.98 for sensing micro-loop waveguide, directional coupler from coefficient of coup r1
=r2=0.99, work as λsTo include λ0Corresponding R when variation in the wave-length coverage of half of Free Spectral Range of MZI inside
(λs) situation of change, that is, sense micro-loop detection before calibration curve；
Figure 15 be the utility model proposes optical waveguide sensor respectively under three environment temperatures, when the temperature phase of MZI
When closing property is equal to temperature dependency of the sensing micro-loop in solution to be detected, detection function R is reflected with sensitive zones detection solution
The relational graph of rate variation；
Figure 16 be the utility model proposes optical waveguide sensor respectively under three environment temperatures, when not having in MZI
When temperature dependency adjustment region, i.e. MZI temperature dependencies are not equal to the temperature dependency for sensing micro-loop, detection function R is with biography
Feel the relational graph of region detection solution variations in refractive index.
In figure：1, the wideband light source of particular range of wavelengths, 2, sense micro-loop input terminal, 3, sensing micro-loop, 4, sensing it is micro-
The duct width w of rings, 5, sensitive zones, 6, sense the straight-through output end of micro-loop, 7, sense the download output end of micro-loop, 8,
MZI, 9, first output end of MZI, 10, second output end of MZI, 11, the detection being connected with first output end of MZI
Device A, 12, the detector B being connected with second output end of MZI, 13, the upper arm waveguide of MZI, 14, width w0Waveguide,
15, the underarm waveguide of MZI, 16, the temperature dependency adjustment region in MZI, 17, the outbound course coupler of MZI, 18, waveguide
Width is from w0Change to w1Noenergy lose spot-size converter, 19, width w1Waveguide, 20, width w1Waveguide length
Degree is La, 21, duct width is from w0Change to w2Noenergy lose spot-size converter, 22, width w2Waveguide, 23, width
For w2Waveguide length be La, the docking of 24, two spot-size converters 21, the docking of 25, two spot-size converters 18.
Specific implementation mode
The utility model is further described below in conjunction with the accompanying drawings.
Referring to Fig.1~Figure 16, a kind of optical waveguide biosensor sensor of low testing cost and temperature-insensitive, including certain wave
The wideband light source 1 of long range, sensing micro-loop 3, sensitive zones 5, the straight-through output end 6 for sensing micro-loop, the download of sensing micro-loop are defeated
Outlet 7, Mach increase first output end 9 of Dare interferometer MZI8, MZI, second output end 10 of MZI, first with MZI
The detector B12 a output end connected detector A11 and be connected with second output end of MZI, the particular range of wavelengths
Wideband light source 1 be composed of the wavelength filter of common wide light source and required wave-length coverage, the specific wavelength model
The wideband light source 1 enclosed is connected with the input terminal 2 of sensing micro-loop, the input of the download output end 7 and MZI of the sensing micro-loop
End is connected, and two output ends 9,10 of MZI are connected with detector A11 and detector B12 respectively.
The upper arm waveguide 13 of MZI is by two kinds of width w014 and w119 compositions, w014 and w1Pass through lossless cone between 19
Shape waveguide 18 connects；The underarm waveguide 15 of MZI is by two kinds of width w014 and w222 compositions, w014 and w2Pass through nothing between 22
The tapered transmission line 21 of damage connects；The upper underarm width of MZI is w0Waveguide between length difference be Δ L, width is w in upper underarm1And w2
Waveguide length be La, and LaMeet relational expression L with Δ La=x × Δ L, wherein x are temperature dependency regulatory factor；Waveguide is wide
Spend w0、w1And w2And the determination of x will meet resonance wavelengths of the MZI with the wavelength shift of variation of ambient temperature and sensing micro-loop
It is identical with the wavelength shift of variation of ambient temperature in detectable substance, i.e., temperature dependency both having the same.
The waveguiding structure for sensing micro-loop 3 and MZI 8 is ridge or bar shaped, and senses the sensitive zones 5 of micro-loop 3 and have
The MZI 8 of protection top covering is in identical detection sample, that is, is detected sample and covered sensitive zones 5 and MZI 8, such as Fig. 4
Shown in sensing micro-loop 3 waveguide cross-section schematic diagram and MZI shown in fig. 58 waveguide cross-section schematic diagram, work as sensing
When 8 temperature dependency having the same of micro-loop 3 and MZI, the duct width w of micro-loop 3 is sensedsThe duct width of 4 and MZI 8 is joined
Number w0 14、w119 and w2Meet following relational expression between 22 and x
Wherein λ0Initial resonant wavelength for the sensing micro-loop selected in design,WithIt is wide respectively
Degree is wsThe effective refractive index and group index of micro-loop waveguide are sensed when 4,WithIt is respectively
Waveguide in MZI 8 is w in widthiWhen corresponding effective refractive index and group index.
Sensing micro-ring resonant wavelength is λs, the performance number I that obtains in detector A 11A(λs) and detector B 12 in obtain
Performance number IB(λs), define detection functionWork as λsTo include λ0Half of MZI 8 inside is freely
In the wave-length coverage of spectral region when variation, the cross-coupling coefficient k of the outbound course coupler 17 of MZImSelection satisfaction make R
(λs) in the wave-length coverage and λsBetween have maximum linear relationship range.
When carrying out the analysis of sensing detection object, it is assumed that be λ to the resonance wavelength of inductive sensing micro-loop 3 when initial time t=00,
Detection function value is R (λ0), it is λ to the resonance wavelength of inductive sensing micro-loop 3 in moment tt, detection function value is R (λt), R (λ0)
With R (λt) all it is always positioned at R (λs) linear relationship within the scope of.Simultaneously in determining cross-coupling coefficient kmUnder, R (λs) line
Sexual intercourse range size can change by adjusting the Free Spectral Range size of MZI 8.
When carrying out the analysis of sensing detection object, R (λ are utilizeds) and λsBetween linear relationship slope value, pass through t moment and t
The detection function value changes delta R (Δ R=R (λ at=0 momentt)-R(λ0)) extrapolate resonance wave long value changes delta in sensing micro-loop 3
λ is extrapolated actually detected further according to the relationship that the concentration of detection and analysis object changes between sensing micro-ring resonant wavelength change Δ λ
The situation of change of object.We will be further elaborated the utility model with actual example below：
Using the utility model proposes sensor structure as shown in Figure 1, realize on the SOI platforms to sensing micro-loop
On piece low cost and temperature-insensitive detection.First, we carry out a theory to the operation principle of device architecture shown in FIG. 1
It introduces.
Assuming that the directional coupler being connected between the input terminal 2 and sensing micro-loop 3 of sensing micro-loop from the coefficient of coup and
Cross-coupling coefficient is (r1,k1), and they meet relational expression r1 2+k1 2=1, while sensing the download output end 7 of micro-loop and passing
The directional coupler being connected between sense micro-loop 3 from the coefficient of coup and cross-coupling coefficient be (r2,k2), and meet relational expression
r2 2+k2 2=1, then sense the transmission spectrum T of micro-loop 3d(λ) can be expressed as
Wherein, a is the one way amplitude transmission factor for sensing micro-loop, it includes the transmission loss and two when ring transmits one week
The loss introduced in directional coupler；LrIt is the ring perimeter for sensing micro-loop 3, neff(ws) it is the effective refraction for sensing micro-loop waveguide
Rate.
Similarly, two output ends 9 of MZI 8 shown in Fig. 1 and 10 transmission spectral function TM1(λ) and TM2(λ) can be with
It is expressed as
Wherein kmIt is the cross-coupling coefficient of the outbound course coupler 17 of MZI, Δ L is the upper arm waveguide 13 of MZI under
Width is w between arm waveguide 150Waveguide 14 length difference, x is that width is w in 13 and 151And w2Waveguide length LaWith Δ L
Between ratio, i.e. x=La/ΔL；neff(w0)、neff(w1) and neff(w2) be respectively width be w0、w1And w2Waveguide correspond to
Effective refractive index.
Assuming that the resonance wavelength of sensing micro-loop is λs, i.e., corresponding wavelength at Energy maximum value in formula (1), then institute in Fig. 1
The performance number obtained in the detector A 11 and detector B 12 that show can be expressed as
Wherein S (λ) is particular range of wavelengths (i.e. λ-To λ+) wideband light source 1 output spectrum, it is to be noted here that
In light source light spectrum range lambda-To λ+It is interior, sense micro-loop download output end 7 frequency spectrum in only there are one resonance peak occur.Utilize formula
(5) and the ratio of the result of (6) takes logarithm that can define a sensing micro-ring resonant wavelength XsDetection function R (λs), it can be with
It is expressed as
Since light source light spectrum S (λ) is already contained in formula (5) and (6), therefore the R (λ in (7)s) value and light source light spectrum tremble
It is dynamic unrelated.Meanwhile the result of formula (7) is by the cross-coupling coefficient k of MZI outbound courses coupler 17mInfluence, later we
It can be seen that the suitable k of selectionmIt can make R (λs) and λsBetween have larger linear relationship range, be conducive to large range of
Sensing detection.
For sensing micro-loop, resonance wave strong point λsResonance Equation can be expressed as
neff(ws)·Lr=mrλs (8)
Wherein mrIt is diffraction time.λ can be obtained using formula (8)sWith the relationship of variation of ambient temperature, i.e. temperature dependency,
It can be expressed as
Wherein ng(ws) it is to sense micro-loop duct width as wsWhen in λsThe group index at place.
Similarly, for the MZI 8 in Fig. 1, transmission spectrum can be expressed as
neff(w0)·ΔL+(neff(w1)-neff(w2)) x Δs L=mm·λm (10)
Wherein mmIt is diffraction time.λ in MZI spectrummIt is with the correlation of variation of ambient temperature
N in formulag(w0)、ng(w1) and ng(w2) it is that duct width takes w in MZI respectively0、w1And w2When corresponding group index.
It can be seen that effective folding of basic mode in the temperature dependency for sensing the humorous spectrum of micro-loop and MZI spectrum and waveguide from formula (9) and (11)
The temperature dependency for penetrating rate is related, i.e.,Simultaneously in formula (11), the temperature dependency of MZI spectrum is also w with width1
And w2Temperature dependency difference the being temperature dependent property regulatory factor x of waveguide is related.
Fig. 6 give this civilization proposition to sense micro-ring resonant wavelength XsRealize the principle signal of temperature-insensitive detection
Figure.Assuming that environment temperature, there are one minor change Δ T, corresponding sensing micro-ring resonant wavelength shift is Δ λTs, the spectrum of MZI
Drift value is Δ λTm.As can be seen from Figure 6 as Δ λTm>ΔλTs, probe function value is from R0Become R2；As Δ λTm<ΔλTs, detection
Functional value is from R0Become R1；However work as Δ λTm=Δ λTs, probe function value remains unchanged.So being wanted in structure proposed in this paper
Sensing micro-loop and MZI temperature dependencies having the same are asked, i.e. formula (9) and (11) is for same wavelength value having the same.
Assuming that λ0Initial resonant wavelength for the sensing micro-loop selected in design, the temperature-insensitive to meet the wavelength detect, then formula
(9) and after (11) simultaneous meet following relationship
WhereinWithBe respectively width be wsSensing micro-loop waveguide in λ0The effective refractive index at place and
Group index,WithBe waveguide in MZI respectively in width it is wiWhen correspond to λ0Place has
Imitate refractive index and group index.
Then we design example the realization of the utility model is expanded on further with one.
Use material：Commercial SOI wafer, top layer silicon thickness are 250nm, and insulation buried oxide layer is 3 μm.In addition to sensing
Outside the sensitive zones of micro-loop, the top covering of entire chip is silicon dioxide layer of protection, in order to ensure sensing micro-loop 3 and MZI 8 have
There are identical environment temperature contact conditions, the two is placed in together in the microchannel that stream has detection solution, Fig. 4 and Fig. 5 are provided
The waveguide cross-section schematic diagram of the two can be ridge (a) or bar shaped (b) etc., and also stream has detection molten to the top covering of MZI 8
Liquid.Herein, it will be assumed that the detection solution that sensitive zones flow through is pure water, and waveguide cross-section is bar shaped, that is, Fig. 4 b and 5b.Fig. 7
The silicon that thickness is 250nm is given, top covering is aqueous solution, under different waveguide width, TE basic modes and TM basic modes in waveguide
Effective refractive index with aqueous solution variations in refractive index relational graph.From this figure, it can be seen that TM basic modes perception aqueous solution refractive index becomes
The ability of change is better than TE basic modes, therefore we select work polarization state of the TM basic modes as waveguide in the design below.
Fig. 8 gives when silicon duct thickness is 250nm, and top covering is respectively SiO2When with pure water, corresponding MZI and biography
The schematic diagram that the temperature dependency of sense micro-loop changes with duct width.From this figure, it can be seen that the temperature phase of MZI and sensing micro-loop
Closing property increases with the increase of duct width, simultaneously for identical width, temperature of the temperature dependency than sensing micro-loop of MZI
Greatly at least 10pm/ DEG C of correlation.In view of requiring and sensing the single mode operation requirement of micro-loop waveguide in actual process, we select
Sense the width w of micro-loop waveguides, conventional waveguide width w in MZI0With narrow duct width w1It is 450nm, while wide wave in MZI
Lead width w2For 800nm.Fig. 9 provides the variation relation for giving the temperature dependency of MZI with temperature dependency regulatory factor x,
It can be seen that under specific duct width, by changing x, the temperature dependency of MZI can be arbitrary value.It is new according to this practicality
To realize temperature-insensitive detection described in type, the temperature phase of MZI should be equal to by sensing temperature dependency of the micro-loop in detecting solution
Guan Xing, as can be seen from Figure 9 in λ both as x=3.50There is equal temperature dependency at=1550nm wavelength.Figure 10 gives
Go out the temperature dependency of the MZI and both sensing micro-loops in x=3.5 with the schematic diagram of wavelength change, it can be seen that
With wavelength departure initial designs wavelength X0When, the temperature dependency difference of the two gradually increases, but relatively small at one
In wave-length coverage, such as in the wave-length coverage of 1540~1555nm, the temperature dependency difference of the two is less than 0.5pm/ DEG C.Due to
In actual detection, sense the wave length shift of micro-loop generally in the wave-length coverage of very little, such as in 5nm, still can be with
One small range of selection simultaneously allows sensing micro-loop to be operated in the wave-length coverage, we can be approximately considered the two in the range in this way
Interior temperature dependency having the same.
After determining the temperature dependency regulatory factor x in MZI, it would be desirable to obtain such a detection relationship be exactly
In required detection range, make as far as possible detection function value R and sense micro-loop resonance wavelength between there are larger linear passes
It is that there are larger linear relationship ranges between range namely R and object concentration to be detected variation.It is defeated that Figure 11 gives MZI two
Transmission spectral function in the wave-length coverage of a Free Spectral Range of exit port centered on by 1550nm wavelength, therefrom can be with
Find out the cross-coupling coefficient k in the outbound course coupler of MZImWhen taking different value, the corresponding performance number of two output ports
Difference, in order to further analyze the two performance numbers and kmBetween relationship, we with reference to formula (7), definition
WhereinWithIt is provided by formula (2) and (3).Figure 12 gives free light centered on by 1550nm wavelength
For ρ with the schematic diagram of wavelength change, Figure 12 b give the amplification in the centre wavelength region of the Free Spectral Range in spectral limit
Figure, there it can be seen that with kmIncrease, the linear relationship range that ρ changes with λ first becomes larger to be reduced afterwards, while the linear model
The slope for enclosing region increases always.So to kmSelection when, between linear relationship range and slope value there are one compromise.
Herein, we choose larger linear relationship range, obtain and work as from Figure 12 bWhen, in a freedom between ρ and λ
There is maximum linear relationship range in the wavelength region of spectral region.However in actual application, due to the suction of aqueous solution
It receives, there is light a degree of energy loss, the energy loss to pass through amplitude transmission factor a when being propagated in sensing micro-loop<1
It embodies, senses the width at the transmission peak maximum of micro-loop downloading end and usually indicated with half maximum value overall with, i.e.,
It can be seen that for wirelessly close to 1 r1And r2And the ring of energy loss, i.e. a=1, FWHM do not become wirelessly
Be bordering on 0, the peak value sharpness of the corresponding ring is higher, which can also be indicated with the Q values of ring, i.e., resonance wavelength and
The ratio of FWHM, Q=λs/FWHM.In addition, it can be seen that for the sensing micro-loop with energy loss, in a<When 1, FWHM is total
It is greater than 0, i.e., always there is certain width at actual sensing micro-ring resonant peak.Figure 13 gives half of free spectrum in MZI
In the wave-length coverage of range, different amplitude transmission factor a, i.e., different resonance peak spectrum widths is to detection function R (λs) influence,
ρ (λ) in figure corresponds to ideally, i.e. the case where when FWHM=0, is derived from Figure 12Situation.It can see
Go out, when a changes are small, i.e., corresponding ring loss becomes larger, detection function value R (λs) it is gradually deviated from ρ values ideally, and phase
The range of linearity region answered also reduces.So when actually detected, due to the unknown of amplitude transmission factor a, needing when detecting
The corresponding R values of sensing micro-loop are calibrated first.
Herein our theoretical validations once the utility model proposes sensor structure sensing capability.Assuming that sensing is micro-
Ring has following parameter：r1=r2=0.99, a=0.98, Lr=50 μm, ws=450nm, ng(ws)=4.522, mr=64, just
Beginning resonance wavelength is λ0=1550nm；MZI has following design parameter：w0=w1=450nm, w2=800, x=3.5,FSRm=8nm, λm=1550nm, mm=58.125, L=72.63 μm of Δ.For ease of comparing, we also design one
A region for not having temperature dependency to adjust in MZI, i.e. x=0, major parameter are as follows：λm=1550nm, mm=85.125,
L=67.77 μm of Δ, FSRm=8nm.According to the parameter of sensing micro-loop, it is about 1.1 × 10 that we, which can calculate its Q value,4, the Q
Value can be obtained easily very much using CMOS technology ripe at present.Figure 14 gives bent to sensing the calibration of micro-loop before detection
Line senses the resonance wavelength of micro-loopsIn the wave-length coverage of half of Free Spectral Range centered on MZI is by 1551nm wavelength
Variation.R (λ are can be seen that from the curves) all meet linear relationship, and Linear Quasi in the very wide range of the wave-length coverage
The degree of correlation of conjunction is equal to 1.
Assuming that using the NaCl solution (various concentration corresponds to different refractivity) of various concentration as sensing analysis object, simultaneously
Sensing micro-loop is in three different environment temperatures, i.e., detection knot when room temperature, room temperature change 10 degree, room temperature changes 20 degree
Fruit.Figure 15 gives the detected value R that sensor structure used by the utility model the obtains relationships changed with detection liquid concentration
Figure, it can be seen that linear characteristic is presented with the variation of detection liquid concentration in R, and in same detection liquid, the value of R
Do not change with the variation of environment temperature, i.e., to the utility model proposes sensor, to sense micro-loop testing result only with
The variation for detecting liquid concentration is related.Figure 16 gives the testing result that temperature dependency regulatory factor is not introduced into MZI, therefrom
It can be seen that detected value R is related with the variation of detection liquid concentration and variation of ambient temperature, this will cause our actually detected results
Prodigious error.It can be seen that the utility model proposes sensor structure can solve the temperature that encounters in sensing micro-loop detection
Sensitive question is spent, simultaneously because introducing cascade MZI carries out the testing cost that power detection greatly reduces sensing micro-loop.
Claims (4)
1. the optical waveguide biosensor sensor of a kind of low testing cost and temperature-insensitive, which is characterized in that the optical waveguide biosensor
Sensor includes the wideband light source of particular range of wavelengths, sensing micro-loop, sensitive zones, the straight-through output end for sensing micro-loop, sensing
Micro-loop download output end, Mach increases first output end of Dare interferometer MZI, MZI, second output end of MZI, with
The detector B first output end of MZI connected detector A and be connected with second output end of MZI, the specific wavelength
The wideband light source of range is composed of the wavelength filter of common wide light source and required wave-length coverage, the specific wavelength
The wideband light source of range is connected with the input terminal of sensing micro-loop, the input of the download output end and MZI of the sensing micro-loop
End is connected, and two output ends of MZI are connected with detector A and detector B respectively.
2. the optical waveguide biosensor sensor of low testing cost and temperature-insensitive as described in claim 1, which is characterized in that institute
The upper arm waveguide of MZI is stated by two kinds of width w0And w1Composition, w0And w1Between pass through lossless tapered transmission line and connect；The underarm of MZI
Waveguide is by two kinds of width w0And w2Composition, w0And w2Between pass through lossless tapered transmission line and connect；The upper underarm width of MZI is w0Wave
Length difference is Δ L between leading, and width is w in upper underarm1And w2Waveguide length be La, and LaMeet relational expression L with Δ La=x ×
Δ L, wherein x are temperature dependency regulatory factor；Duct width w0、w1And w2And the determination of x will meet MZI with environment temperature
The wavelength shift of variation and the resonance wavelength of sensing micro-loop are identical with the wavelength shift of variation of ambient temperature in detectable substance,
That is the two temperature dependency having the same.
3. the optical waveguide biosensor sensor of low testing cost and temperature-insensitive as claimed in claim 1 or 2, feature exist
In the waveguiding structure of the sensing micro-loop and MZI are bar shaped or ridge, and sense the sensitive zones of micro-loop and have in protection
The MZI of covering is in identical detection sample, that is, is detected sample and covered sensitive zones and MZI, when sensing micro-loop and MZI tools
When having identical temperature dependency, the duct width w of micro-loop is sensedsWith the duct width parameter w of MZI0、w1And w2And between x
Meet following relational expression
Wherein λ0Initial resonant wavelength for the sensing micro-loop selected in design,WithBe respectively width be ws
When sense micro-loop waveguide effective refractive index and group index,WithIt is in MZI respectively
Waveguide is w in widthiWhen corresponding effective refractive index and group index.
4. the optical waveguide biosensor sensor of low testing cost and temperature-insensitive as claimed in claim 1 or 2, feature exist
In the sensing micro-ring resonant wavelength is λs, the performance number I that obtains in detector AA(λs) and detector B in the power that obtains
Value IB(λs), define detection functionWork as λsTo include λ0Half of Free Spectral Range of MZI inside
Wave-length coverage in variation when, the cross-coupling coefficient k of the outbound course coupler of MZImSelection satisfaction make R (λs) in the wave
In long range and λsBetween have maximum linear relationship range.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820557790.7U CN208076394U (en) | 2018-04-19 | 2018-04-19 | A kind of optical waveguide biosensor sensor of low testing cost and temperature-insensitive |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820557790.7U CN208076394U (en) | 2018-04-19 | 2018-04-19 | A kind of optical waveguide biosensor sensor of low testing cost and temperature-insensitive |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN208076394U true CN208076394U (en) | 2018-11-09 |
Family
ID=64044165
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201820557790.7U Active CN208076394U (en) | 2018-04-19 | 2018-04-19 | A kind of optical waveguide biosensor sensor of low testing cost and temperature-insensitive |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN208076394U (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108318453A (en) * | 2018-04-19 | 2018-07-24 | 浙江工业大学 | A kind of optical waveguide biosensor sensor of low testing cost and temperature-insensitive |
| CN109813681A (en) * | 2019-01-09 | 2019-05-28 | 东南大学 | A kind of liquid refractive index sensor based on nested micro-ring resonator |
| WO2023071004A1 (en) * | 2021-10-27 | 2023-05-04 | 赛丽科技(苏州)有限公司 | Optical sensor chip and optical sensing system |
-
2018
- 2018-04-19 CN CN201820557790.7U patent/CN208076394U/en active Active
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108318453A (en) * | 2018-04-19 | 2018-07-24 | 浙江工业大学 | A kind of optical waveguide biosensor sensor of low testing cost and temperature-insensitive |
| CN108318453B (en) * | 2018-04-19 | 2023-09-26 | 浙江工业大学 | Optical waveguide biosensor with low detection cost and insensitive temperature |
| CN109813681A (en) * | 2019-01-09 | 2019-05-28 | 东南大学 | A kind of liquid refractive index sensor based on nested micro-ring resonator |
| WO2023071004A1 (en) * | 2021-10-27 | 2023-05-04 | 赛丽科技(苏州)有限公司 | Optical sensor chip and optical sensing system |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US7145660B2 (en) | Micro-resonator based optical sensor | |
| CN208076394U (en) | A kind of optical waveguide biosensor sensor of low testing cost and temperature-insensitive | |
| US8111402B2 (en) | Optical sensing based on overlapping optical modes in optical resonator sensors and interferometric sensors | |
| US9052291B2 (en) | Optical sensor based on a broadband light source and cascaded waveguide filters | |
| US9335263B2 (en) | Optical circuit for sensing a biological entity in a fluid and method of configuring the same | |
| WO1994024542A1 (en) | Method and apparatus for determination of refractive index | |
| CN108318453A (en) | A kind of optical waveguide biosensor sensor of low testing cost and temperature-insensitive | |
| Cięszczyk et al. | A novel simple TFBG spectrum demodulation method for RI quantification | |
| US11255746B2 (en) | Photonic resonator analyzer and characterizing a photonic resonator | |
| US11906368B2 (en) | Temperature measurement system and method using optical signal transmission through an optical interferometer | |
| US9068950B2 (en) | Vernier photonic sensor data-analysis | |
| CN105572074A (en) | Refractive index detection method based on on-chip integrated optical waveguide biosensor chip | |
| CN205538647U (en) | Integrated fiber waveguide biosensor chip is gone up to apyrexial piece | |
| CN105628621B (en) | The optical waveguide biosensor sensor chip that a kind of on piece without heat integrates | |
| Prasad et al. | Full-range detection in cascaded microring sensors using thermooptical tuning | |
| Chatzianagnostou et al. | Theory and sensitivity optimization of plasmo-photonic Mach-Zehnder interferometric sensors | |
| Singha et al. | On-chip photonic temperature sensor using micro ring resonator | |
| TWI467158B (en) | Application method of optical filter spectral linewidth | |
| Abdulla et al. | Sensing platform based on micro-ring resonator and on-chip reference sensors in SOI | |
| Liu et al. | Refractive Index Sensor Based on Few-mode Silicon-Nitride Micro-Ring Resonator | |
| A Goncharenko et al. | Liquid concentration sensor based on slot waveguide microresonators | |
| CN112964668B (en) | Substance concentration detection device and method based on resonator | |
| Yoo et al. | Monolithic Integration of Si 3 N 4 Ring Resonator and On-Chip Fourier Transform Spectrometer for The Lab-On-A-Chip Biosensor | |
| DE GOEDE et al. | Double Al2O3 Microring Resonator for Self-Referenced Sensing Applications | |
| Ahmed et al. | Transitioning from resistance devices to photonic devices for temperature measurements |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant |