CN208049028U - A kind of production system suitable for Nifuratel tablet - Google Patents
A kind of production system suitable for Nifuratel tablet Download PDFInfo
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- CN208049028U CN208049028U CN201721732817.3U CN201721732817U CN208049028U CN 208049028 U CN208049028 U CN 208049028U CN 201721732817 U CN201721732817 U CN 201721732817U CN 208049028 U CN208049028 U CN 208049028U
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Abstract
A kind of production system suitable for Nifuratel tablet includes：Vacuum device, head tank, seal pipe, beater grinder, wet granulator, oscillating granulator, boiling drier, pelletizing machine, lifting material transferring machine, mixing machine and tablet press machine, vacuum device respectively with beater grinder, wet granulator, connection at the top of boiling drier and pelletizing machine, head tank is connect by seal pipe with beater grinder top, beater grinder bottom end is connect by seal pipe with wet granulator top, wet granulator is connect by seal pipe with oscillating granulator, oscillating granulator is connect by seal pipe with boiling drier top, fluidized drying motor spindle is connect by seal pipe with pelletizing machine top, whole grain motor spindle at the top of lifting material transferring machine and mixing machine by connecting, mixing motor spindle at the top of lifting material transferring machine and tablet press machine by connecting；Wherein, vacuum device includes：Vacuum extractor, vacuum chamber and pulsed dust-removing device.The utility model is saved manually, and cross contamination is avoided.
Description
Technical field
The utility model is related to medical pharmaceutical technology fields, and in particular to a kind of production system suitable for Nifuratel tablet
System.
Background technology
Oral medicine Nifuratel tablet be used for treat bacterial vaginosis BV, trichomonas vaginitis, vulvovaginal white read ball
Bacterium disease, urinary system infection contamination, alimentary canal amcbiasis and Giardiasis.Its wide indications mainly acts on microbial enzyme system,
Coacetylase, interference Microbial saccharides metabolism is inhibited to have to urinary system, disease of digestive system and significantly control to play bacteriostasis
Therapeutic effect.While killing pathogenic bacteria, Bacillus acidi lactici is protected, improves vagina ecological environment, pregnant woman can be safe to use；It can be used for
The treatment of women unmarried and in menstrual period, and can be used for bridegroom's or husband's side treatment.And it is not necessarily to drug combination, as a kind of ideal gynaecology
Anti-inflammatory drugs are worth selection of clinical application and promote.There are a large amount of powderies and graininess in the specific production process of Nifuratel tablet
The transhipment of material, handling, processing, transhipment, handling, processing and etc. generally by being accomplished manually, due to each step
All there may be more or less dust in operating process, the waste to valuable ingredient of traditional Chinese medicine is caused, production environment and system are caused
Pollution, influences worker's health.
Therefore, a series of improvement have been carried out to solve the above-mentioned problems.
Utility model content
The purpose of the utility model is to provide a kind of production systems suitable for Nifuratel tablet, to overcome existing skill
Disadvantages mentioned above present in art and deficiency.
A kind of production system suitable for Nifuratel tablet, which is characterized in that including：Vacuum device, head tank, sealing
Pipe, beater grinder, wet granulator, oscillating granulator, boiling drier, pelletizing machine, lifting material transferring machine, mixing machine and tabletting
Machine, the vacuum device is connect at the top of beater grinder, wet granulator, boiling drier and pelletizing machine respectively, described
Head tank is connect by seal pipe with beater grinder top, and the beater grinder bottom end passes through seal pipe and wet granulator
Top connects, and the wet granulator connect by seal pipe with oscillating granulator, the oscillating granulator by seal pipe and
Boiling drier top connects, and the fluidized drying motor spindle is connect by seal pipe with pelletizing machine top, the pelletizing machine bottom
Portion at the top of lifting material transferring machine and mixing machine by connecting, and the mixing motor spindle at the top of lifting material transferring machine and tablet press machine by connecting
It connects；
Wherein, the vacuum device includes：Vacuum extractor, vacuum chamber and pulsed dust-removing device, the vacuum means
It sets and is connect at the top of vacuum chamber, the vacuum chamber is respectively arranged on beater grinder, wet granulator, boiling drier and pelletizing machine
Top, the pulsed dust-removing device are connect with vacuum chamber.
Further, the vacuum extractor includes：Whirlpool air pump, gas tank, exhaust tube, electronic valve and control centre, it is described
Whirlpool air pump is connect with gas tank, and by being connect at the top of exhaust tube and vacuum chamber, the electronic valve is set on exhaust tube the gas tank,
The control centre is set on gas tank, and the control centre connect with whirlpool air pump and electronic valve respectively.
Further, the vacuum chamber includes：Sealed gas chamber, exhaust port, suction port, qi of chong channel ascending adversely mouth, dedusting filter
And pressure sensor, the sealed gas chamber bottom end is simultaneously equipped with exhaust port, suction port is equipped at the top of the sealed gas chamber, described
Sealed gas chamber side wall is equipped with qi of chong channel ascending adversely mouth, and the sealed gas chamber is internally provided with pulsed dust-removing device, and the sealed gas chamber passes through exhaust
Port is connected to beater grinder, wet granulator, boiling drier and pelletizing machine respectively, and the sealed gas chamber is by being evacuated end
Mouth is connect with exhaust tube, and the dedusting filter is set at exhaust port, and the pressure sensor is set to sealed gas chamber inner wall
On, the pressure sensor is connect with controller.
Further, the pulsed dust-removing device includes：Pulse valve, airbag, qi of chong channel ascending adversely pipe, communicating pipe and compressed gas source, it is described
Airbag, pulse valve, qi of chong channel ascending adversely pipe are set in sealed gas chamber, and the airbag bottom is described by being connected in the middle part of pulse valve and qi of chong channel ascending adversely pipe
Qi of chong channel ascending adversely pipe both ends are respectively protruding into exhaust port, and the communicating pipe, described communicating pipe one end connected with airbag with qi of chong channel ascending adversely mouth through connection
It connects, the communicating pipe other end is connect with compressed gas source.
Further, the seal pipe is equipped with valve.
The beneficial effects of the utility model：
The utility model prepares Nifuratel tablet using vacuum feeding, the dustless production on line technology of totally-enclosed, utmostly
Reduce being in direct contact for people and material, without dust leakage while avoiding pollution to drug in the process, the conveying of material is made to exist
It is completed in one closed environment, can both save manually, reduce cost, and can be to avoid cross contaminations such as environment.
Description of the drawings
Fig. 1 is the structure chart of the utility model.
Reference numeral：
Vacuum device 100, vacuum extractor 110, whirlpool air pump 111, gas tank 112, exhaust tube 113,114 and of electronic valve
Controller 115.
Vacuum chamber 120, sealed gas chamber 121, exhaust port 122, suction port 123, qi of chong channel ascending adversely mouth 124, dedusting filter
125 and pressure sensor 126.
Pulsed dust-removing device 130, pulse valve 131, airbag 132, qi of chong channel ascending adversely pipe 133, communicating pipe 134 and compressed gas source 135.
Head tank 200, seal pipe 300, valve 310, beater grinder 400, wet granulator 500, oscillating granulator
600, boiling drier 700, pelletizing machine 800, lifting material transferring machine 900, mixing machine 1000 and tablet press machine 2000.
Specific implementation mode
Below in conjunction with specific embodiment, progress explanation is made to the utility model.It should be understood that following embodiment is merely to illustrate
The utility model is not for restriction the scope of the utility model.
Embodiment 1
Fig. 1 is the structure chart of the utility model.
As shown in Figure 1, a kind of production system suitable for Nifuratel tablet includes：Vacuum device 100, head tank 200,
Seal pipe 300, beater grinder 400, wet granulator 500, oscillating granulator 600, boiling drier 700, pelletizing machine 800,
Lifting material transferring machine 900, mixing machine 1000 and tablet press machine 2000, vacuum device 100 respectively with beater grinder 400, wet method system
The 800 top connection of grain machine 500, boiling drier 700 and pelletizing machine, head tank 200 pass through seal pipe 300 and beater grinder
400 tops connect, and 400 bottom end of beater grinder is connect by seal pipe 300 with 500 top of wet granulator, wet granulator
500 are connect by seal pipe 300 with oscillating granulator 600, and oscillating granulator 600 passes through seal pipe 300 and boiling drier 700
Top connects, and 700 bottom of boiling drier is connect by seal pipe 300 with 800 top of pelletizing machine, and 800 bottom of pelletizing machine passes through
Lifting material transferring machine 900 is connect with 1000 top of mixing machine, and 1000 bottom of mixing machine passes through lifting material transferring machine 900 and tablet press machine 2000
Top connects；
Wherein, vacuum device 100 includes：Vacuum extractor 110, vacuum chamber 120 and pulsed dust-removing device 130 are taken out true
Empty device 110 is connect with 120 top of vacuum chamber, and vacuum chamber 120 is respectively arranged on beater grinder 400, wet granulator 500, boiling
800 top of drying machine 700 and pelletizing machine is risen, pulsed dust-removing device 130 is connect with vacuum chamber 120.
Vacuum extractor 110 includes：Whirlpool air pump 111, gas tank 112, exhaust tube 113, electronic valve 114 and controller 115,
Whirlpool air pump 111 is connect with gas tank 112, and gas tank 112 is connect by exhaust tube 113 with 120 top of vacuum chamber, and electronic valve 114 is set
In on exhaust tube 113, controller 115 is set on gas tank 112, and controller 115 connects with whirlpool air pump 111 and electronic valve 114 respectively
It connects.
Vacuum chamber 120 includes：Sealed gas chamber 121, exhaust port 122, suction port 123, qi of chong channel ascending adversely mouth 124 and dust removal and filtration
Device 125,121 bottom end of sealed gas chamber are simultaneously equipped with exhaust port 122, and 121 top of sealed gas chamber is equipped with suction port 123, closed
121 side wall of gas chamber is equipped with qi of chong channel ascending adversely mouth 124, and sealed gas chamber 121 is internally provided with pulsed dust-removing device 130, and sealed gas chamber 121 passes through row
Gas port 122 is connected to beater grinder 400, wet granulator 500, boiling drier 700 and pelletizing machine 800 respectively, closed
Gas chamber 121 is connect by suction port 123 with exhaust tube 113, and dedusting filter 125 is set at exhaust port 122, the pressure
Force snesor 126 is set on 121 inner wall of sealed gas chamber, and the pressure sensor 126 is connect with controller 115.
Pulsed dust-removing device 130 includes：Pulse valve 131, airbag 132, qi of chong channel ascending adversely pipe 133, communicating pipe 134 and compressed gas source
135, airbag 132, pulse valve 131, qi of chong channel ascending adversely pipe 133 are set in sealed gas chamber 121, and 132 bottom of airbag passes through pulse valve 131 and punching
133 middle part connection of tracheae, 133 both ends of qi of chong channel ascending adversely pipe are respectively protruding into exhaust port 122, and communicating pipe 134 is with qi of chong channel ascending adversely mouth 124 through company
It connects, communicating pipe, 134 one end was connect with airbag 132, and communicating pipe, 134 other end was connect with compressed gas source 135.
Seal pipe 300 is equipped with valve 310.
Before work, all electronic valves 114 and valve 310 are in closed state；Whirlpool air pump 111 starts, corresponding hammer
The electronic valve 114 of pulverizer 400 is opened under the control of controller 115, and 400 internal gas of beater grinder passes through dust removal and filtration
Device 125, exhaust port 122, sealed gas chamber 121, exhaust tube 113 and gas tank 112 are extracted out by whirlpool air pump 111, hammer type crushing
400 inside of machine forms negative-pressure vacuum, and controller 115 closes correspondence in due course according to 126 transmission datas of corresponding pressure sensor
Electronic valve 114, the valve 310 in seal pipe 300 between head tank 200 and beater grinder 400 is opened, in head tank 200
Auxiliary material beater grinder 400 is sent to by vacuum suction by seal pipe 300 after, close head tank 200 and beater grinder
Valve 310 between 400 in seal pipe 300, beater grinder 400 start, pulverize and sieve to auxiliary material；The process that pulverizes and sieves is completed
Afterwards, whirlpool air pump 111 starts, and the electronic valve 114 of corresponding wet granulator 500 is opened, and controller 115 is according to pressure sensor
126 500 internal datas of wet granulator transmitted close corresponding electronic valve 114 in due course, open and are set to beater grinder 400
Valve 310 between wet granulator 500, auxiliary material are sent to by vacuum suction in wet granulator 500 by seal pipe 300,
The valve 310 opened is closed, wet granulator 500 works, and is premixed successively to auxiliary material, adds slurry, stirring and cutting action system
Standby softwood；Start oscillating granulator 600 and boiling drier 700, opens and be set to wet granulator 500 and oscillating granulator 600
Between valve 310, after the softwood made enters oscillating granulator 600, close open valve 310, softwood is in oscillating granulator
The wet whole grain of 20 mesh screens sieving is carried out in 600；Whirlpool air pump 111 starts, and the electronic valve 114 of corresponding boiling drier 700 is opened,
700 internal data of boiling drier that controller 115 is transmitted according to pressure sensor 126 closes corresponding electronic valve in due course
114, the valve 310 being set between oscillating granulator 600 and boiling drier 700 is opened, wet granular is automatically drawn by vacuum to boiling
It rises in drying machine 700, closes open valve 310,700 control material temperature of boiling drier is dry to water at 30~40 DEG C
Divide≤3.0%；Whirlpool air pump 111 starts, and the electronic valve 114 of corresponding pelletizing machine 800 is opened, and controller 115 is according to pressure sensing
800 internal data of pelletizing machine that device 126 is transmitted closes corresponding electronic valve 114 in due course, opens and is set to 700 He of boiling drier
Valve 310 between pelletizing machine 800, dried particle are automatically drawn by vacuum into pelletizing machine 800, and open valve is closed
310, pelletizing machine 800 starts, and doing whole grain using 20 mesh sieve to dried particle obtains dry particl；The boosted material rotaring machine of dry particl
900 seamless deliveries start mixing machine 1000 to mixing machine 1000, and dry particl is mixed together 10min and obtains with glidant, lubricant
Always mixed particle；Always in boosted material rotaring machine 900 seamless delivery to tablet press machine 2000 of mixed particle, tablet press machine 2000, adjustment sheet are opened
Weight, control tablet hardness about 60~80N, obtain Nifuratel tablet；Pulse valve 131 is periodically opened, the compression in compressed gas source 135
Gas sprays from 133 both ends of qi of chong channel ascending adversely pipe, determines dedusting filter 125 through communicating pipe 134, airbag 132, pulse valve 131
When dedusting.
The utility model prepares Nifuratel tablet using vacuum feeding, the dustless production on line technology of totally-enclosed, utmostly
Reduce being in direct contact for people and material, without dust leakage while avoiding pollution to drug in the process, the conveying of material is made to exist
It is completed in one closed environment, can both save manually, reduce cost, and can be to avoid cross contaminations such as environment.
Specific embodiment of the present utility model is illustrated above, but the utility model is not limited thereto, only
The objective of the utility model is not departed from, the utility model there can also be various change.
Claims (5)
1. a kind of production system suitable for Nifuratel tablet, which is characterized in that including：Vacuum device (100), head tank
(200), seal pipe (300), beater grinder (400), wet granulator (500), oscillating granulator (600), boiling drier
(700), pelletizing machine (800), lifting material transferring machine (900), mixing machine (1000) and tablet press machine (2000), the vacuum device
(100) connect respectively at the top of beater grinder (400), wet granulator (500), boiling drier (700) and pelletizing machine (800)
It connects, the head tank (200) is connect by seal pipe (300) with beater grinder (400) top, the beater grinder
(400) bottom end is connect by seal pipe (300) with wet granulator (500) top, and the wet granulator (500) passes through sealing
Pipe (300) is connect with oscillating granulator (600), and the oscillating granulator (600) passes through seal pipe (300) and boiling drier
(700) top connects, and boiling drier (700) bottom is connect by seal pipe (300) with pelletizing machine (800) top, institute
It states pelletizing machine (800) bottom to connect by lifting material transferring machine (900) and mixing machine (1000) top, mixing machine (1000) bottom
Portion at the top of lifting material transferring machine (900) and tablet press machine (2000) by connecting；
Wherein, the vacuum device (100) includes：Vacuum extractor (110), vacuum chamber (120) and pulsed dust-removing device
(130), it is connect at the top of the vacuum extractor (110) and vacuum chamber (120), the vacuum chamber (120) is respectively arranged on hammer powder
At the top of broken machine (400), wet granulator (500), boiling drier (700) and pelletizing machine (800), the pulsed dust-removing device
(130) it is connect with vacuum chamber (120).
2. a kind of production system suitable for Nifuratel tablet according to claim 1, it is characterised in that：It is described to vacuumize
Device (110) includes：Whirlpool air pump (111), gas tank (112), exhaust tube (113), electronic valve (114) and controller (115), institute
It states whirlpool air pump (111) to connect with gas tank (112), the gas tank (112) passes through exhaust tube (113) and vacuum chamber (120) top
Connection, the electronic valve (114) are set on exhaust tube (113), and the controller (115) is set on gas tank (112), the control
Device (115) is connect with whirlpool air pump (111) and electronic valve (114) respectively.
3. a kind of production system suitable for Nifuratel tablet according to claim 2, it is characterised in that：The vacuum chamber
(120) include：Sealed gas chamber (121), exhaust port (122), suction port (123), qi of chong channel ascending adversely mouth (124), dedusting filter
(125) and pressure sensor (126), sealed gas chamber (121) bottom end are simultaneously equipped with exhaust port (122), the sealed gas chamber
(121) top is equipped with suction port (123), and sealed gas chamber (121) side wall is equipped with qi of chong channel ascending adversely mouth (124), the sealed gas chamber
(121) be internally provided with pulsed dust-removing device (130), the sealed gas chamber (121) by exhaust port (122) respectively with hammer powder
Broken machine (400), wet granulator (500), boiling drier (700) are connected to pelletizing machine (800), the sealed gas chamber (121)
It being connect with exhaust tube (113) by suction port (123), the dedusting filter (125) is set at exhaust port (122),
The pressure sensor (126) is set on sealed gas chamber (121) inner wall, and the pressure sensor (126) connects with controller (115)
It connects.
4. a kind of production system suitable for Nifuratel tablet according to claim 3, it is characterised in that：The pulse removes
Dirt device (130) includes：Pulse valve (131), airbag (132), qi of chong channel ascending adversely pipe (133), communicating pipe (134) and compressed gas source (135),
The airbag (132), pulse valve (131), qi of chong channel ascending adversely pipe (133) are set in sealed gas chamber (121), and airbag (132) bottom is logical
It being connected in the middle part of extra pulse valve (131) and qi of chong channel ascending adversely pipe (133), qi of chong channel ascending adversely pipe (133) both ends are respectively protruding into exhaust port (122),
With qi of chong channel ascending adversely mouth (124) through connection, described communicating pipe (134) one end is connect the communicating pipe (134) with airbag (132), described
Communicating pipe, (134) other end connect with compressed gas source (135).
5. a kind of production system suitable for Nifuratel tablet according to claim 1, it is characterised in that：The seal pipe
(300) it is equipped with valve (310).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201721732817.3U CN208049028U (en) | 2017-12-13 | 2017-12-13 | A kind of production system suitable for Nifuratel tablet |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201721732817.3U CN208049028U (en) | 2017-12-13 | 2017-12-13 | A kind of production system suitable for Nifuratel tablet |
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| Publication Number | Publication Date |
|---|---|
| CN208049028U true CN208049028U (en) | 2018-11-06 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201721732817.3U Expired - Fee Related CN208049028U (en) | 2017-12-13 | 2017-12-13 | A kind of production system suitable for Nifuratel tablet |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110840852A (en) * | 2019-10-16 | 2020-02-28 | 河北天成药业股份有限公司 | Metformin hydrochloride tablet and production process and production equipment thereof |
-
2017
- 2017-12-13 CN CN201721732817.3U patent/CN208049028U/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110840852A (en) * | 2019-10-16 | 2020-02-28 | 河北天成药业股份有限公司 | Metformin hydrochloride tablet and production process and production equipment thereof |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20190820 Address after: 2/F, Building No. 5, 333 Guiping Road, Xuhui District, Shanghai, 2003 Patentee after: Shanghai Hongguan Pharmaceutical Technology Co.,Ltd. Address before: Room 426, Building 4, 333 Guiping Road, Xuhui District, Shanghai, 2003 Patentee before: SHANGHAI SUNRISE MEDICAL TECHNOLOGY CO.,LTD. |
|
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20181106 Termination date: 20211213 |