CN208043737U - Loading device for Matrix-Assisted Laser Desorption Ionization Time of Flight - Google Patents

Loading device for Matrix-Assisted Laser Desorption Ionization Time of Flight Download PDF

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Publication number
CN208043737U
CN208043737U CN201820551486.1U CN201820551486U CN208043737U CN 208043737 U CN208043737 U CN 208043737U CN 201820551486 U CN201820551486 U CN 201820551486U CN 208043737 U CN208043737 U CN 208043737U
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China
Prior art keywords
intake passage
loading device
target platform
body part
sample intake
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Active
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CN201820551486.1U
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Chinese (zh)
Inventor
周晓光
李运涛
于新爱
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New Biological Technology (qingdao) Co Ltd
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New Biological Technology (qingdao) Co Ltd
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Abstract

The utility model discloses a kind of loading device for Matrix-Assisted Laser Desorption Ionization Time of Flight, including is formed with the shell of accommodating chamber;Positioned at the indoor load target platform of accommodating chamber;And sampling device;It includes body part and baffle to carry target platform;Sampling device includes the sample intake passage for carrying the disengaging of target platform body part, includes window in housing sidewall;Along window circumferential direction, window internal face, which is recessed inwardly, is formed with the first annular groove, forms groove between the sampling device wall outer surface corresponding to the first annular groove and sample intake passage passway edge, sealing element is provided in the groove;After load target platform body part enters sample intake passage, the corner of the close sampling device of baffle is pressed on a side surface of sealing element inner end.The loading device can ensure the vacuum insulation of device accommodating chamber, and can realize that there are effective sealings when larger pressure difference between accommodating chamber and sample intake passage by the adjusting of device self structure during biological target plate loads and takes out.

Description

Loading device for Matrix-Assisted Laser Desorption Ionization Time of Flight
Technical field
The utility model is related to a kind of loading devices.It is ionized for Matrix Assisted Laser Desorption more particularly, to one kind The loading device of flight time mass spectrum.
Background technology
Matrix-Assisted Laser Desorption Ionization Time of Flight (MALDI-TOF) is a kind of high-end analytical instrument of precision, Ion flight space needs very high vacuum environment, it is desirable that environment vacuum degree can reach 1e-7Torr, even higher.According to biology The operation requirement of experiment, existing loading device generally include with the internal accommodating chamber in vacuum state and facilitate biological target Plate into and out of the sampling device with sample intake passage, for target plate load and pop up structure normally referred to as carry target platform, target plate Into or device for ejecting will pass through from the sample intake passage of sampling device in the accommodating chamber of vacuum state, i.e., target plate is loaded and is taken It is needed while going out by sample intake passage and in the accommodating chamber isolating seal of vacuum state.Therefore, sample intake passage needs to undergo high State conversion between low vacuum or between high vacuum and atmospheric environment, and when state is converted, sample intake passage and loading device It needs to be effectively isolated between accommodating chamber, so that high-vacuum chamber can still keep vacuum state, this contributes to target plate to enter in true After the accommodating chamber of dummy status, system can be rapidly achieved the required vacuum degree of experiment, while protect molecular pump, high vacuum inspection Survey the generation of the vacuum such as meter and detection device.
In the prior art, the sealing means generally use sealing being isolated between equipment accommodating chamber and two cavity of sample intake passage Part seals, and sealing element is placed in integrally to be exposed in a vacuum with sealing element when in the matched groove of sealing element size, carrying the movement of target platform, When no external force is fixed, sealing element can be drawn onto in the accommodating chamber in vacuum state.In addition, according to existing standard, place The groove dimensions of sealing element are all to be subject to sealing element more fully to be compressed by both sides contact surface, although sealing element has certain bullet Property, but in this case, the adjustable decrement very little or almost nil of sealing element.
In addition also have in the prior art and vacuum accommodating chamber and sample introduction are realized by control mechanism transverse direction or circumferential movement Isolation between two cavity of channel and unicom, but its own possessed sealing structure is compressed without longitudinal direction and regulatory function, The machining accuracy of groove corresponding to sealing element is depended entirely on to the pressure of sealing element, can not equally realize the longitudinal direction to sealing element It adjusts, and when sealing effect is bad, it is difficult to which ideal isolating seal effect is reached by effective adjustment of mechanism itself.
Utility model content
In view of the above problems, the technical problem to be solved by the present invention is to provide one kind being used for Matrix Assisted Laser Desorption The loading device of ionization time of flight mass spectrometry.The loading device can ensure to add during biological target plate loads and takes out The vacuum insulation for setting accommodating chamber is carried, and can realize accommodating chamber and sample intake passage by the adjusting of loading device self structure Between there are effective sealings when larger pressure difference.
In order to solve the above technical problems, the utility model uses following technical proposals:
A kind of loading device for Matrix-Assisted Laser Desorption Ionization Time of Flight, the loading device include:
It is formed with the shell of accommodating chamber;
Positioned at the indoor load target platform of the accommodating chamber;And
Outside the shell and combine the sampling device for being fixed on housing sidewall outer surface;
The load target platform includes body part, and circumferential along body part by the end surface of the separate sampling device of body part To the baffle extended far from body part direction;
The sampling device includes the sample intake passage for carrying the disengaging of target platform body part, include in the housing sidewall with The corresponding window that the disengaging sample intake passage is passed through for carrying target platform body part in the sample intake passage passway;
Along window circumferential direction, the window internal face, which is recessed inwardly, is formed with the first annular groove, which runs through institute State housing sidewall outer surface, first annular groove and the sampling device wall outer surface corresponding to the edge of sample intake passage passway Between form groove, be provided with sealing element in the groove;
After carrying target platform body part and entering sample intake passage, the corner of the close sampling device of the baffle is pressed on described close On one side surface of sealing inner end.
Further, it is preferable to which scheme is, the sealing element includes the main body of structure annular in shape, the main body radial section it is straight Diameter is not less than the internal diameter of the groove.
Further, it is preferable to scheme is, and in the direction of motion for carrying target platform body part, the separate body part of the baffle End face be located at the inside of window internal face, and the end face of the separate body part of the baffle is located at the outside of sealing element inner end.
Further, it is preferable to scheme is, and in the direction of motion for carrying target platform body part, the internal face of the sample intake passage Positioned at the inside of the window internal face.
Further, it is preferable to which scheme is, along sample intake passage passway circumferential direction, sample intake passage passway edge includes There are the second annular groove for being recessed inwardly and being formed by sampling device wall outer surface, the second annular groove to be collectively formed with the first annular groove for holding Receive the groove of the sealing element.
Further, it is preferable to which scheme is, second annular groove includes the groove body side wall close to the sample intake passage, the groove body The inner surface of side wall is in the inclined-plane extended out.
Further, it is preferable to which scheme is, the corner of the close sampling device of the baffle includes and the seal surface The contact surface of abutting, the contact surface are inclined-plane or cambered surface.
Further, it is preferable to which scheme is, the shell includes at least the first shell with opening, and combines and be fixed on institute State the second shell of the plate-like structure of opening, the sampling device, which combines, is fixed on second shell outer surface, and described Sampling device is corresponding, and the window is formed in the second shell.
Further, it is preferable to which scheme is, the loading device further includes being located at the indoor slide device of the accommodating chamber;It is described Slide device includes:
With the relatively-stationary fixed part of shell position;And
The moving portion that can be slided along fixed part extending direction on the fixed part;
The load target platform is in conjunction with being fixed in the moving portion.
Further, it is preferable to which scheme is, the loading device further includes the branch for being connected and fixed the load target platform with moving portion Fagging, the support plate is by least three adjusting screws in conjunction with being fixed on the surface of the moving portion;Wherein at least three Region is triangular in shape defined by the projection of adjusting screw in the horizontal plane.
The beneficial effects of the utility model are as follows:
1, loading device provided by the utility model passes in and out sample intake passage by the improvement of structure using target platform is carried Slide device with the baffle movement on dynamic load target platform, and by the abutting between the baffle and sealing element, and then realizes load dress Accommodating chamber is set during biological target plate loads and takes out, remains and is sealed with the vacuum insulation of external environment.And The loading device is simple in structure, capacity is small, can effectively realize high vacuum environment and low vacuum environment or Gao Zhen in loading device Altitude and atmospheric environment be isolated and sealing.
2, loading device provided by the utility model drives baffle mobile and is matched with sealing element by slide device The mode of conjunction can make the corner of baffle with certain angle of inclination further to sealing element by adjusting the distance of baffle Forward Horizontal direction and the pressing force of vertical direction are imposed, the adjustable work(to loading device accommodating chamber isolating seal effect is realized Energy.
3, in loading device provided by the utility model, under the action of slide device, sealing element is because by baffle Corner squeezes and generates flexible deformation and be close to trench wall, compensates for trench wall since mechanical processing is formed by surface not Enough smooth defects.
4, when the load target platform for carrying target plate returns in loading device accommodating chamber, baffle after carrying target platform with moving, no longer Sealing element is compressed, accommodating chamber is connected with sample intake passage, by low vacuum to high vacuum in formation sample intake passage during this Conversion, the moment that baffle is detached with sealing element, since there are huge pressure differences to be formed between sample intake passage and accommodating chamber Prodigious impact force, when coordinating not close between sealing element and trench wall, sealing element is easily inhaled into accommodating chamber, and In one kind provided by the utility model preferably loading device structure, by forming second in sampling device wall outer surface The design of groove is collectively formed in the design of annular groove by the second annular groove and the first annular groove, avoid the appearance of the above situation, protects Having demonstrate,proved sealing element will not be inhaled into because of the immense pressure difference between accommodating chamber and sample intake passage in accommodating chamber, realize Better seal isolation effect.
5, loading device provided by the utility model can be such that the indoor vacuum degree of loading device accommodating chamber is continuously reduced to 1e-7Torr (≈ 1.33e-5Pa), and this state can be kept, above-mentioned vacuum degree be enough for microorganism ribosomal protein molecule from The detection of son provides ideal vacuum environment.
Description of the drawings
Specific embodiment of the present utility model is described in further detail below in conjunction with the accompanying drawings.
Fig. 1 shows the assembling structure schematic diagram of the provided loading device of the utility model.
Fig. 2 shows the structural schematic diagrams that target platform is carried in the provided loading device of the utility model.
Fig. 3 shows the structural schematic diagram of the provided loading device of the utility model.
Fig. 4 shows the Section A-A figure of loading device structure shown in Fig. 3 of part.
Fig. 5 shows the portions the B enlarged diagram of Fig. 4.
Specific implementation mode
In order to illustrate more clearly of the utility model, the utility model is done into one with reference to preferred embodiments and drawings The explanation of step.Similar component is indicated with identical reference numeral in attached drawing.It will be appreciated by those skilled in the art that below Specifically described content is illustrative and be not restrictive, and should not limit the scope of protection of the utility model with this.
In following description given, for purposes of illustration, in order to provide comprehensive reason to one or more embodiment Solution, numerous specific details are set forth.It may be evident, however, that these realities can also be realized without these specific details Apply mode.In other examples, one or more embodiment for ease of description, well known structure and equipment are with block diagram Form show.
In order to illustrate more clearly of the utility model, the utility model is done into one with reference to preferred embodiments and drawings The explanation of step.Similar component is indicated with identical reference numeral in attached drawing.It will be appreciated by those skilled in the art that below Specifically described content is illustrative and be not restrictive, and should not limit the scope of protection of the utility model with this.
In conjunction with shown in Fig. 1 to Fig. 5, the utility model provides a kind of for Matrix Assisted Laser Desorption ionization flight time matter The loading device of spectrum, the loading device include:It is formed with the shell of accommodating chamber;Positioned at the indoor load target platform of the accommodating chamber 1;And outside the shell and combine the sampling device 2 for being fixed on housing sidewall outer surface.
The load target platform 1 include body part 11, and by body part 11 separate sampling device 2 end surface along ontology Portion 11 is circumferential to the baffle 12 extended far from 11 direction of body part;The sampling device 2 includes for carrying 1 body part 11 of target platform The sample intake passage 21 of disengaging includes corresponding with 2 passway of the sample intake passage in the housing sidewall for carrying 1 ontology of target platform Portion 11 passes through the window 3 for passing in and out the sample intake passage 21.It should be noted that it will be appreciated by persons skilled in the art that institute Vacuum state chamber should be remained by stating accommodating chamber, and the internal face of the sample intake passage 21 is located at 3 internal face of the window Inside passes in and out the sample intake passage 21 convenient for carrying 1 body part 11 of target platform across window 3.In addition schematic structure is combined, for the ease of The assembly of loading device and simplify technique, in present embodiment, specifically, the shell includes the first shell with opening Body (not shown), and the second shell 4 in conjunction with the plate-like structure for being fixed on the opening.Relative to by first shell And the loading device shell with accommodating chamber is collectively formed in second shell, the sampling device 2, which combines, is fixed on second shell 4 outer surface of body, corresponding with the sampling device 2, the window 3 is formed in the second shell 4.Further, edge The window 3 is circumferential, and 3 internal face of the window, which is recessed inwardly, is formed with the first annular groove 31, and first annular groove 31 is through described the Two shells, 4 side-wall outer side surface, first annular groove 31 and 2 side wall of sampling device corresponding to 21 passway edge of sample intake passage Groove 5 is formed between outer surface, is provided with first seal 51 in the groove 5, it is preferable that the material of the first seal 51 For rubber.After 1 body part 11 of load target platform enters sample intake passage 21, the corner of the close sampling device 2 of the baffle 12 121 are pressed on a side surface of 51 inner end of the first seal.In embodiment provided by the utility model, use First seal 51 realizes being isolated between accommodating chamber and sample intake passage 21 with the cooperation of groove 5, due to first seal 51 Can by the corner 121 of baffle 12 squeeze and generate flexible deformation and be close to 5 inner wall of groove, and then compensate for 5 inner wall of groove by It is formed by not smooth enough the defect in surface in mechanical processing.
Further, the loading device further includes being located at the indoor slide device of the accommodating chamber;The slide device Including:With the relatively-stationary fixed part of shell position 6;And it can be slided along 6 extending direction of fixed part on the fixed part 6 Moving portion 7;The load target platform 1 is in conjunction with being fixed in the moving portion 7.
The structure in conjunction with shown in Fig. 1 and Fig. 3, it is preferable that the loading device further includes by the load target platform 1 and moving portion 7 The support plate 8 being connected and fixed, the support plate 8 is by three adjusting screws 9 in conjunction with being fixed on the surface of the moving portion 7; Region is triangular in shape defined by the projection of wherein three adjusting screws 9 in the horizontal plane.The purpose of three adjusting screws 9 is set It is, by the adjustment of three adjusting screws 9, can be adjusted in the horizontal direction to carrying target platform 1 relative to slide device, with Just it carries and preferably coordinates between target platform 1 and sample intake passage 21, the loading convenient for biological target plate and taking-up.
Loading device provided by the utility model is installed on the indoor slide device of accommodating chamber when the biological target plate of load Moving portion 7 is moved along 6 extending direction of the fixed part, passes through window 3 into the sample intake passage of sampling device 2 with dynamic load target platform 1 In 21, carry target platform 1 it is completely in place after, be formed in carry it is on 1 body part 11 of target platform and with carry 1 body part 11 of target platform in rigid connection Baffle 12 abutted with the first seal 51, i.e. the corner 121 of the close sampling device 2 of baffle 12 is pressed on described first On one side surface of 51 inner end of sealing element.At this point, the corner 121 of the close sampling device 2 of baffle 12 can be to first seal 51 impose the pressing force F of horizontal direction and vertical direction, and 51 axial surface of first seal and radial end face is made to be produced by compression It gives birth to flexible deformation and is adjacent to 5 inner wall of groove, realize being isolated between sample intake passage 21 and accommodating chamber.Then, sample introduction dress is opened The intake valve set makes 21 inside of sample intake passage be communicated with air.At this point, it is 1e- that the both sides of loading device, which are vacuum degree on one side, The accommodating chamber of 7Torr (≈ 1.33e-5Pa), another side are the sample intake passages of atmospheric environment, and pressure is 1 atmospheric pressure (≈ 1e5Pa)。
Further, the data detected according to high vacuum gauge, when sample intake passage 21 has reached required with accommodating chamber Isolation effect after, the indoor vacuum pressure value of accommodating chamber can continue to decline, i.e., vacuum degree persistently increases, until stable reading.
When perfect condition is not achieved in vacuum degree in accommodating chamber, in the effect of accommodating chamber and 21 pressure difference of sample intake passage Under, high-vacuum chamber vacuum degree can decline, i.e., the vacuum pressure value detected by high vacuum gauge can increase.It, can under this state It is moved by slide device moving portion 7, regulating fender 12 is moved to close to the direction of first seal 51, Forward baffle appropriate 12, the corner 121 of the close sampling device 2 of baffle 12 can be made to be pressed further by first seal 51, make its preferably with groove 5 Inner wall is adjacent to.During the adjustment, it is observed that the reading of high vacuum gauge can continuously decline, until the indoor vacuum of accommodating chamber Degree reaches perfect condition, disclosure satisfy that the condition of Bioexperiment.So far, realize in accommodating chamber with atmospheric environment it is effective every From sealing, the charge and discharge operations of biological target plate can be carried out.
When needing load target platform 1 to return in accommodating chamber, it is first shut off being located between sample intake passage 21 and atmospheric environment Intake valve on the sampling device 2 opens the by-passing valve between sampling device 2 and low vacuum accumulator, by sample intake passage 21 Vacuum degree be extracted into about 2e-2Torr (≈ 2.66Pa), be converted to low vacuum state in sample intake passage 21.Later, bypass is closed Valve returns in accommodating chamber with dynamic load target platform 1 positioned at the indoor slide device moving portion of accommodating chamber 7, is formed in load target at this time It is on 1 body part 11 of platform and with carry 1 body part 11 of target platform in moving after rigidly connected baffle 12, no longer squeeze first seal 51, unicom between accommodating chamber and sample intake passage 21 is formed during carrying target platform 1 and baffle 12 returns to accommodating chamber By the conversion of low vacuum to high vacuum in sample intake passage 21.
In addition, in conjunction with Fig. 4 and Fig. 5, in loading device provided by the utility model, the groove of first seal 51 is accommodated Pass through the 2 wall outer surface shape of sampling device corresponding to 4 side-wall outer side surface of second shell and 21 passway edge of sample intake passage At this requires 51 main bodys of first seal to be not only embedded in the groove 5, it is also necessary to which there are can be with the baffle 12 The matched part for exposing groove 5 in corner 121, it is preferred that the first seal 51 includes structure annular in shape Main body, the diameter of the main body radial section are not less than the internal diameter of the groove 5;And in 1 body part 11 of load target platform In the direction of motion, the end face of the separate body part 11 of the baffle 12 is located at the inside of 3 internal face of window, in addition the baffle 12 End face far from body part 11 is located at the outside of 51 inner end of first seal.
When the load target platform 1 for carrying target plate returns in loading device accommodating chamber, baffle 12 after carrying target platform 1 with moving, no First seal 51 is compressed again, and accommodating chamber is connected with sample intake passage 21, by low true in formation sample intake passage 21 during this Sky arrive high vacuum conversion, the moment that baffle 12 is detached with first seal 51, between sample intake passage 21 and accommodating chamber due to There are huge pressure differences can form prodigious impact force, when coordinating not close between 5 inner wall of first seal 51 and groove, First seal 51 is easily inhaled into accommodating chamber, in view of the above-mentioned problems, in conjunction with shown in Fig. 4 and Fig. 5, present embodiment provides One kind being preferably carried out mode, and along 21 passway of sample intake passage circumferential direction, 21 passway edge of the sample intake passage includes Be recessed inwardly the second annular groove 22 formed by 2 wall outer surface of sampling device, and the second annular groove 22 is collectively formed with the first annular groove 31 Groove 5 for accommodating the first seal 51.The design of groove is collectively formed by the second annular groove 22 and the first annular groove 31, The appearance that can avoid the above problem, ensure that first seal 51 will not be because of huge between accommodating chamber and sample intake passage 21 Pressure difference and be inhaled into accommodating chamber, realize better seal isolation effect.
Preferably, in present embodiment, second annular groove 22 includes the groove body side wall close to the sample intake passage 21 221, the inner surface 2211 of the groove body side wall 221 is in the inclined-plane extended out.It can be with convenient for the groove body inner surface of the second annular groove 22 The adaptation installation of 51 surface of first seal, and when first seal 51 is squeezed by the corner 121 of baffle 12, first seal 51 surfaces can fit closely fixation with the groove body inner surface of the second annular groove 22.It should be noted that in conjunction with schematic structure, in order to Realize better isolating seal effect, in the recording device that present embodiment is provided, on 4 outer surface of the second shell also Include third annular groove 10, it includes second seal 101 to be formed between 2 wall outer surface of the third annular groove 10 and sampling device Groove body.
In addition, as further preferably scheme, in conjunction with Fig. 5, the corner 121 of the close sampling device 2 of the baffle 12 Include the contact surface 1211 abutted with 51 surface of the first seal, which is inclined-plane or cambered surface.Pass through Above-mentioned set-up mode so that 12 corner 121 of baffle, which is contacted with the way of contact on 51 surface of first seal by line face, becomes face Face contacts, and on the one hand avoids the damage by 12 corner 121 of baffle to 51 surface of first seal of line face contact, influences sample introduction Isolating seal effect between channel 21 and accommodating chamber.On the other hand in biological target plate loading procedure, 12 corner 121 of baffle The way of contact with 51 surface of first seal is plane-plane contact, be conducive to the corner 121 of baffle 12 with certain angle of inclination into One step imposes horizontal direction and the pressing force of vertical direction to first seal 51, realizes and loading device accommodating chamber is isolated The adjustable function of sealing effect.
In conclusion the load provided by the utility model for Matrix-Assisted Laser Desorption Ionization Time of Flight Device, by the improvement of structure, it can be achieved that loading device accommodating chamber is protected always during biological target plate loads and takes out It holds and is sealed with the vacuum insulation of external environment.And the side that baffle is mobile and is coordinated with sealing element is driven by slide device Formula realizes the adjustable function to loading device accommodating chamber isolating seal effect.In addition the loading device structure, also passes through The design of the second annular groove is formed in sampling device wall outer surface, ensure that sealing element will not be because of accommodating chamber and sample intake passage Between immense pressure difference and be inhaled into accommodating chamber, realize better seal isolation effect.
Obviously, above-described embodiment of the utility model is only intended to clearly illustrate the utility model example, and It is not the restriction to the embodiment of the utility model, for those of ordinary skill in the art, in above description On the basis of can also make other variations or changes in different ways, all embodiments can not be exhaustive here, It is every to belong to obvious changes or variations that the technical solution of the utility model is extended out still in the utility model The row of protection domain.

Claims (10)

1. a kind of loading device for Matrix-Assisted Laser Desorption Ionization Time of Flight, which is characterized in that the load Device includes:
It is formed with the shell of accommodating chamber;
Positioned at the indoor load target platform of the accommodating chamber;And
Outside the shell and combine the sampling device for being fixed on housing sidewall outer surface;
The load target platform includes body part, and circumferential to remote along body part from the end surface of the separate sampling device of body part The baffle extended from body part direction;
The sampling device includes the sample intake passage for carrying the disengaging of target platform body part, include in the housing sidewall with it is described The corresponding window that the disengaging sample intake passage is passed through for carrying target platform body part in sample intake passage passway;
Along window circumferential direction, the window internal face, which is recessed inwardly, is formed with the first annular groove, which runs through the shell Between sampling device wall outer surface corresponding to body sidewall outer surface, first annular groove and sample intake passage passway edge Groove is formed, sealing element is provided in the groove;
After load target platform body part enters sample intake passage, the corner of the close sampling device of the baffle is pressed on the sealing element On one side surface of inner end.
2. loading device according to claim 1, which is characterized in that the sealing element includes the main body of structure annular in shape, The diameter of the main body radial section is not less than the internal diameter of the groove.
3. loading device according to claim 1, which is characterized in that in the direction of motion for carrying target platform body part, The end face of the separate body part of the baffle is located at the inside of window internal face, and the end face of the separate body part of the baffle is located at The outside of sealing element inner end.
4. loading device according to claim 1, which is characterized in that in the direction of motion for carrying target platform body part, The internal face of the sample intake passage is located at the inside of the window internal face.
5. loading device according to claim 4, which is characterized in that along the sample intake passage passway circumferential direction, it is described into Sample channel passway edge includes the second annular groove for being recessed inwardly and being formed by sampling device wall outer surface, the second annular groove and The groove for accommodating the sealing element is collectively formed in one annular groove.
6. loading device according to claim 5, which is characterized in that second annular groove includes logical close to the sample introduction The inner surface of the groove body side wall in road, the groove body side wall is in the inclined-plane extended out.
7. loading device according to claim 1, which is characterized in that the corner of the close sampling device of the baffle includes There is the contact surface abutted with the seal surface, which is inclined-plane or cambered surface.
8. loading device according to claim 1, which is characterized in that the shell includes at least the first shell with opening Body, and in conjunction with the second shell for the plate-like structure for being fixed on the opening, the sampling device, which combines, is fixed on second Hull outside surface, corresponding with the sampling device, the window is formed in the second shell.
9. loading device according to claim 1, which is characterized in that the loading device further includes being located at the accommodating chamber Indoor slide device;The slide device includes:
With the relatively-stationary fixed part of shell position;And
The moving portion that can be slided along fixed part extending direction on the fixed part;
The load target platform is in conjunction with being fixed in the moving portion.
10. loading device according to claim 9, which is characterized in that the loading device further includes by the load target platform The support plate being connected and fixed with moving portion, the support plate is by least three adjusting screws in conjunction with being fixed on the moving portion On surface;Region is triangular in shape defined by the projection of wherein at least three adjusting screw in the horizontal plane.
CN201820551486.1U 2018-04-18 2018-04-18 Loading device for Matrix-Assisted Laser Desorption Ionization Time of Flight Active CN208043737U (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108375626A (en) * 2018-04-18 2018-08-07 融智生物科技(青岛)有限公司 Loading device for Matrix-Assisted Laser Desorption Ionization Time of Flight

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108375626A (en) * 2018-04-18 2018-08-07 融智生物科技(青岛)有限公司 Loading device for Matrix-Assisted Laser Desorption Ionization Time of Flight

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