CN207933428U

CN207933428U - A kind of genetic chip of layering setting

Info

Publication number: CN207933428U
Application number: CN201820177556.1U
Authority: CN
Inventors: 迟翔宇; 李微微; 吴冰; 鲁明
Original assignee: Tianjin Wei Polymer Diagnostic Technology Co Ltd
Current assignee: Tianjin Wei Polymer Diagnostic Technology Co Ltd
Priority date: 2018-02-01
Filing date: 2018-02-01
Publication date: 2018-10-02
Anticipated expiration: 2028-02-01

Abstract

The utility model discloses a kind of genetic chips of layering setting, including shielded box, chip, notice plate, timer, storage compartment and partition board, the shielded box side wall equidistantly opens up four storage compartments, and storage compartment is separated by partition board, the chip is inserted into storage compartment, the shielded box side wall is located at storage box respective heights and is fixed with notice plate, timer is installed at the top of the shielded box, this genetic chip film overlay device layer can effectively prevent respectively reacting the interference between aperture on base membrane layer, ensure that reaction is normally carried out, and the chip type for marking storage compartment to be stored on notice plate, it avoids confusion each chip position, simultaneously, when using timer, at the end of reaction time, timer alarm is reminded, research reaction result in time, keep experimental result more acurrate, the genetic chip is simple in structure, it is easy to operate.

Description

A kind of genetic chip of layering setting

Technical field

The utility model is related to biochip technology field, specially a kind of genetic chip of layering setting.

Background technology

The prototype of genetic chip is that the mid-80 proposes.The sequencing principle of genetic chip is sequencing by hybridization method, i.e., Method by carrying out determining nucleic acid sequence with the nucleic acid probe hybridization of one group of known array, sequence is secured in one piece of substrate surface The probe of the known target nucleotide of row.As the nucleic acid sequence TATGCAATCTAG for carrying fluorescent marker in solution, with genetic chip When the nucleic acid probe of upper corresponding position generates complementary matching, by determining the strongest probe location of fluorescence intensity, one group of sequence is obtained The probe sequence of row complete complementary.The sequence of target nucleic acid can be recombinated out accordingly.

A kind of genetic chip of effective protection base membrane layer conversion zone is mentioned in existing patent CN205133582U, is passed through Lid protects probe array, but this device is not easy to differentiate experiment type, causing cannot be complete when carrying out multigroup experiment Whole experiment process is manipulated, for this purpose, it is proposed that a kind of genetic chip of layering setting.

Utility model content

The purpose of this utility model is to provide a kind of genetic chips of layering setting, to solve to carry in above-mentioned background technology The problem of going out.

To achieve the above object, the utility model provides the following technical solutions：A kind of genetic chip of layering setting, including Shielded box, chip, notice plate, timer, storage compartment and partition board, the shielded box side wall equidistantly opens up four storage compartments, and deposits It puts storehouse to be separated by partition board, the chip is inserted into storage compartment, and the shielded box side wall is located at storage box respective heights and is fixed with mark Remember board, timer is installed at the top of the shielded box.

Preferably, the chip includes bearing bed, base membrane layer, coating layer, hole array, probe array and baffle, described Bearing bed end is fixedly connected with baffle, and the bearing bed upper surface is placed with base membrane layer, and basement membrane layer surface is provided with probe Array, the base membrane layer upper surface is placed with coating layer, and overlay film layer surface is provided with the probe array pair with basement membrane layer surface The hole array answered.

Preferably, the bearing bed offers out film slot close to baffle one end.

Preferably, the baffle sidewall is equipped with handle.

Preferably, the probe array multiplies 5 arrays using 4.

Preferably, the partition board upper surface and chip lower surface polish smooth.

Compared with prior art, the utility model has the beneficial effects that：

1, the protein material of experiment is placed on probe array surface by the utility model, and coating layer can be effectively prevent The interference between aperture is respectively reacted on base membrane layer, it is ensured that reaction is normally carried out, and chip is inserted into shielded box, in notice plate subscript The chip type that note storage compartment is stored, each chip position of avoiding confusion.

2, when the utility model uses timer, at the end of the reaction time, timer alarm is reminded, in time research reaction As a result, keeping experimental result more acurrate, the genetic chip is simple in structure, easy to operate.

Description of the drawings

Fig. 1 is the utility model overall structure diagram；

Fig. 2 is the utility model chip structure schematic diagram；

Fig. 3 is the utility model shielded box structural schematic diagram.

In figure：1- shielded boxs；2- chips；3- notice plates；4- timers；5- storage compartments；6- bearing beds；7- base membrane layers；8- Coating layer；9- hole arrays；10- probe arrays；11- baffles；12- handles；13- ply bar scots；14- partition boards.

Specific implementation mode

The following will be combined with the drawings in the embodiments of the present invention, carries out the technical scheme in the embodiment of the utility model Clearly and completely describe, it is clear that the described embodiments are only a part of the embodiments of the utility model, rather than whole Embodiment.Based on the embodiments of the present invention, those of ordinary skill in the art are without making creative work The every other embodiment obtained, shall fall within the protection scope of the present invention.

- 3 are please referred to Fig.1, the utility model provides a kind of technical solution：A kind of genetic chip of layering setting, including every From case 1, chip 2, notice plate 3, timer 4, storage compartment 5 and partition board 14,1 side wall of the shielded box equidistantly opens up four storage compartments 5, and storage compartment 5 is separated by partition board 14, the chip 2 is inserted into storage compartment 5, and 1 side wall of the shielded box is located at storage box correspondence Height is fixed with notice plate 3, and 1 top of the shielded box is equipped with timer 4.

The chip 2 includes bearing bed 6, base membrane layer 7, coating layer 8, hole array 9, probe array 10 and baffle 11, institute It states 6 end of bearing bed to be fixedly connected with baffle 11,6 upper surface of the bearing bed is placed with base membrane layer 7, and 7 surface of base membrane layer is set It is equipped with probe array 10,7 upper surface of the base membrane layer is placed with coating layer 8, and 8 surface of coating layer is provided with and 7 table of base membrane layer The 10 corresponding hole array 9 of probe array in face.

The bearing bed 6 offers out film slot 13 close to 11 one end of baffle, and coating layer 8 and base membrane layer 7 are not easy to separate, open up Ply bar scot 13 is convenient separately to take out coating layer 8, is convenient for cleaning device.

11 side wall of the baffle is equipped with handle 12, convenient for extracting and being put into chip out.

The probe array 10 multiplies 5 arrays using 4, and such setting can ensure the setting of multiple subregions, and can ensure The project accuracy of each subregion.

14 upper surface of the partition board and 2 lower surface of chip polish smooth, and the frictional force for reducing chip 2 and partition board 14 is convenient It the extraction of chip 2 and is put into.

Operation principle：The protein material of experiment is placed in the probe array 10 on 7 surface of base membrane layer, coating layer 8 It can effectively prevent respectively reacting the interference between aperture on base membrane layer 7, it is ensured that reaction is normally carried out, and chip 2 is inserted into shielded box In, 2 type of chip for marking storage compartment 5 to be stored on notice plate 3, then 2 position of each chip of avoiding confusion uses timing 4 timing of device, at the end of the reaction time, 4 warning reminding of timer, the gene device is simple in structure, easy to operate.

It should be noted that herein, relational terms such as first and second and the like are used merely to a reality Body or operation are distinguished with another entity or operation, are deposited without necessarily requiring or implying between these entities or operation In any actual relationship or order or sequence.Moreover, the terms "include", "comprise" or its any other variant are intended to Non-exclusive inclusion, so that the process, method, article or equipment including a series of elements is not only wanted including those Element, but also include other elements that are not explicitly listed, or further include for this process, method, article or equipment Intrinsic element.

While there has been shown and described that the embodiments of the present invention, for the ordinary skill in the art, It is appreciated that can these embodiments be carried out with a variety of variations in the case where not departing from the principles of the present invention and spirit, repaiied Change, replace and modification, the scope of the utility model are defined by the appended claims and the equivalents thereof.

Claims

1. a kind of genetic chip of layering setting, including shielded box (1), chip (2), notice plate (3), timer (4), storage compartment (5) and partition board (14), it is characterised in that：Shielded box (1) side wall equidistantly opens up four storage compartments (5), and storage compartment (5) by Partition board (14) separates, and the chip (2) is inserted into storage compartment (5), and it is solid that shielded box (1) side wall is located at storage box respective heights Surely there is notice plate (3), timer (4) is installed at the top of the shielded box (1).

2. a kind of genetic chip of layering setting according to claim 1, it is characterised in that：The chip (2) includes holding Carrier layer (6), base membrane layer (7), coating layer (8), hole array (9), probe array (10) and baffle (11), the bearing bed (6) End is fixedly connected with baffle (11), and bearing bed (6) upper surface is placed with base membrane layer (7), and base membrane layer (7) surface is arranged There is probe array (10), base membrane layer (7) upper surface is placed with coating layer (8), and coating layer (8) surface is provided with and basement membrane The corresponding hole array (9) of probe array (10) on layer (7) surface.

3. a kind of genetic chip of layering setting according to claim 2, it is characterised in that：The bearing bed (6) is close Baffle (11) one end offers out film slot (13).

4. a kind of genetic chip of layering setting according to claim 3, it is characterised in that：Baffle (11) the side wall peace Equipped with handle (12).

5. a kind of genetic chip of layering setting according to claim 2, it is characterised in that：The probe array (10) is adopted Multiply 5 arrays with 4.

6. a kind of genetic chip of layering setting according to claim 2, it is characterised in that：Partition board (14) upper surface It is polished smooth with chip (2) lower surface.