CN207918842U - A kind of stem cell tissue collecting bottle - Google Patents
A kind of stem cell tissue collecting bottle Download PDFInfo
- Publication number
- CN207918842U CN207918842U CN201721881994.8U CN201721881994U CN207918842U CN 207918842 U CN207918842 U CN 207918842U CN 201721881994 U CN201721881994 U CN 201721881994U CN 207918842 U CN207918842 U CN 207918842U
- Authority
- CN
- China
- Prior art keywords
- bottle
- filter
- stem cell
- bottle body
- intermediate inner
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 210000000130 stem cell Anatomy 0.000 title claims abstract description 42
- 239000011148 porous material Substances 0.000 claims abstract description 26
- 238000001914 filtration Methods 0.000 claims abstract description 21
- 239000002245 particle Substances 0.000 abstract description 7
- 238000000926 separation method Methods 0.000 abstract description 2
- 238000010586 diagram Methods 0.000 description 5
- 239000008280 blood Substances 0.000 description 4
- 210000004369 blood Anatomy 0.000 description 4
- PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 description 2
- 229910000831 Steel Inorganic materials 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 239000010959 steel Substances 0.000 description 2
- 230000001954 sterilising effect Effects 0.000 description 2
- 208000019838 Blood disease Diseases 0.000 description 1
- 208000026350 Inborn Genetic disease Diseases 0.000 description 1
- 208000001738 Nervous System Trauma Diseases 0.000 description 1
- 208000010378 Pulmonary Embolism Diseases 0.000 description 1
- 239000004411 aluminium Substances 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- 208000007502 anemia Diseases 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 238000005530 etching Methods 0.000 description 1
- 208000016361 genetic disease Diseases 0.000 description 1
- 208000019622 heart disease Diseases 0.000 description 1
- 208000014951 hematologic disease Diseases 0.000 description 1
- 238000011134 hematopoietic stem cell transplantation Methods 0.000 description 1
- 208000018706 hematopoietic system disease Diseases 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 208000028412 nervous system injury Diseases 0.000 description 1
- 229910052759 nickel Inorganic materials 0.000 description 1
- 230000000505 pernicious effect Effects 0.000 description 1
- 229920000052 poly(p-xylylene) Polymers 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 238000011476 stem cell transplantation Methods 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 208000019553 vascular disease Diseases 0.000 description 1
Landscapes
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The utility model discloses a kind of stem cell tissue collecting bottles, including bottle, opening and filtration members, the bottle upper end is equipped with the opening, filtration members are equipped among the bottle, the filtration members include first filter and the second filter, the bottle is divided into upper bottle body and lower bottle body, the intermediate inner bottle is nested in the upper bottle body and lower bottle body, the intermediate inner bottle bottom is equipped with second filter, first filter is equipped in the upper bottle body, internal thread is equipped in the upper bottle body and lower bottle body, the intermediate inner bottle is externally provided with and the matched external screw thread of the internal thread, the first filter is equipped with several first pores, second filter is equipped with the second pore, the diameter of first pore is more than stem cell diameter, the diameter of second pore is less than stem cell diameter.The utility model provides the separation realized to marrow little particle and marrow bulky grain in stem cell.
Description
Technical field
The utility model belongs to stem cell collection equipment technical field, more particularly to a kind of stem cell tissue collecting bottle.
Background technology
With deepening continuously for stem cell and stem cell clinical application, it is pernicious that hematopoietic stem cell transplantation has become radical cure
The effective means of blood disease, alpastic anemia, certain genetic diseases etc..Stem cell transplantation in recent years is gradually applied
In the treatment of middle and advanced stage malignant solid tumor, heart disease, nervous system injury, histoorgan reparation, diabetes, vascular diseases etc..
Stem cell collection point is generally both sides posterior superior iliac spine and anterior superior spine, acquired marrow be actually blood with
The mixed liquor of marrow, also known as " marrow blood ".The total amount about 0.5-1 liters of adopted marrow blood.Due to having one in the marrow of acquisition
A little marrow little particles and marrow bulky grain, need to take filtering and crush measure, pulmonary embolism occurs when being transfused to prevent marrow blood.Often
Filter method includes syringe needle filtering and stainless (steel) wire filtering.Also all kinds of corrupt practices creep in for syringe needle filtering, and stainless (steel) wire filtering needs
One special device about the equipment of the type is difficult on the market at present to find.
Utility model content
According to technical problem described in above-mentioned background technology, the utility model provides a kind of stem cell tissue collecting bottle,
To realize the separation to marrow little particle and marrow bulky grain in stem cell.
The technical solution adopted in the utility model is a kind of stem cell tissue collecting bottle, including bottle, opening and filtering
Part, the bottle upper end are equipped with the opening, filtration members are equipped among the bottle, and the opening is equipped with conduit connector sleeve,
The conduit connector sleeve connects the first tube at one end, and the first conduit other end connects a threeway pullover, the threeway pullover
Other two pullover is separately connected the second conduit and third conduit, and second conduit is connect with syringe, the third conduit
Connect human stem cell harvester;The filtration members include first filter and the second filter, and the first filter is set
In the top of second filter, the bottle is divided into upper bottle body and lower bottle body, and the intermediate inner bottle is nested on described
In bottle and lower bottle body, the intermediate inner bottle bottom is equipped with second filter, and the first filtering is equipped in the upper bottle body
Internal thread is equipped in device, the upper bottle body and lower bottle body, the intermediate inner bottle is externally provided with and the matched outer spiral shell of the internal thread
Line, the first filter are equipped with several first pores, and second filter is equipped with the second pore, first pore
Diameter be more than stem cell diameter, the diameter of second pore is less than stem cell diameter.
Preferably, it is respectively equipped with adjuster on first conduit and third conduit.
Preferably, step is equipped in the lower bottle body, the step supports the intermediate inner bottle.
Preferably, the external screw thread set by the intermediate inner bottle is located at the both ends of the intermediate inner bottle, in the centre
The middle section of bottle is equipped with graduation apparatus.
Preferably, the first filter is located at the top of set internal thread in the upper bottle body, is set in the upper bottle body
There are step, the step to support the first filter.
Preferably, second filter and the intermediate inner bottle are integrated.
Preferably, first pore and the second pore are inverted round stage structure.
The utility model compared with prior art, has advantageous effect below:
The utility model is simple in structure, and operation is easy, and the opening is equipped with syringe by guide-tube structure, using syringe
Differential pressure principle carries out the acquisition of stem cell;The bottle of setting can preserve blood flow temporarily, and set first filter can
To filter marrow bulky grain, the second set filter can filter marrow little particle, the first filter and the second filtering
The stem cell that set intermediate inner bottle can be arrived with store collected between device, the intermediate inner bottle and upper bottle body and lower bottle body it
Between be threadedly coupled, can will store the intermediate inner bottle taking-up of stem cell, the utility model by rotating upper bottle body and lower bottle body
So that swift to operate and convenient for disassembly and assembly.
Description of the drawings
Fig. 1 is the structural schematic diagram of the utility model;
Fig. 2 is the structural schematic diagram of the utility model first filter and the second filter;
Fig. 3 is the utility model first filter and the inside side structure schematic view of the second filter;
Fig. 4 is the structural schematic diagram of inner bottle among the utility model;
Fig. 5 is the structural schematic diagram of the utility model upper bottle body;
Fig. 6 is the structural schematic diagram of the utility model lower bottle body.
In figure:1, bottle 11, upper bottle body 111, step 12, lower bottle body 121, step 13, internal thread 14, external screw thread 2, opening
3, intermediate inner bottle 31, graduation apparatus 4, filtration members 41, first filter 411, the first pore 42, the second filter 421, second are thin
Hole 50, the first conduit 52, threeway pullover 53, the second conduit 54, third conduit 55, syringe 56, is adjusted conduit connector sleeve 51
Device.
Specific implementation mode
The following will be combined with the drawings in the embodiments of the present invention, carries out the technical scheme in the embodiment of the utility model
Clearly and completely describe, it is clear that the described embodiments are only a part of the embodiments of the utility model, rather than whole
Embodiment.Based on the embodiments of the present invention, those of ordinary skill in the art are without making creative work
The every other embodiment obtained, shall fall within the protection scope of the present invention.
It is illustrated in conjunction with Fig. 1-6 pairs of the technical solution of the utility model, a kind of stem cell tissue collecting bottle, including bottle
1, opening 2, intermediate inner bottle 3 and filtration members 4,1 upper end of the bottle are equipped with the opening 2, filtering are equipped among the bottle 1
Part 4, the opening 2 are equipped with, conduit connector sleeve 50, first conduit of connection of conduit connector sleeve 50,51 one end, and described first
51 other end of conduit connects a threeway pullover 52, and 52 other two pullover of the threeway pullover is separately connected the second conduit 53 and the
Three conduits 54, second conduit 53 are connect with syringe 55, and the third conduit 54 connects human stem cell harvester;Institute
It includes first filter 41 and the second filter 42 to state filtration members 4, and the first filter 41 is placed in second filter 42
Top, the bottle 1 divides for upper bottle body 11 and lower bottle body 12, the intermediate inner bottle 3 be nested in the upper bottle body 11 and under
In bottle 12,3 bottom of intermediate inner bottle is equipped with second filter 42, and first filter is equipped in the upper bottle body 11
41, the upper bottle body 11 and lower bottle body 12 are interior equipped with internal thread 13, and the intermediate inner bottle 3 is externally provided with and the internal thread 13
Matched external screw thread 14, the first filter 41 are equipped with several first pores 411, and second filter 42 is equipped with the
The diameter of two pores 421, first pore 411 is more than stem cell diameter, and the diameter of second pore 421 is less than stem cell
Diameter.
Flow velocity in order to control marrow mixed liquor keeps the marrow mixed liquor filter effect in collecting bottle best, and described first leads
It is respectively equipped with adjuster 56 on pipe 51 and third conduit 54.
Refering to fig. 1 and Fig. 6, specifically, be equipped with step 121 in the lower bottle body 12, the step 121 support it is described in
Between inner bottle 3.
Refering to fig. 1 and Fig. 4, acquired stem cell volume is observed for convenience, it is outer set by the intermediate inner bottle 3
Screw thread 14 is located at the both ends of the intermediate inner bottle 3, and the middle section of the intermediate inner bottle 3 is equipped with graduation apparatus 31.
Refering to fig. 1 and Fig. 5, specifically, the first filter 41 is located at set internal thread 13 in the upper bottle body 11
Top, the upper bottle body 11 is interior to be equipped with step 111, and the step 111 supports the first filter 41.
Refering to Fig. 4, second filter 42 is integrated with the intermediate inner bottle 3.
Refering to Fig. 3, in order to make marrow mixed liquor smoothly flow down, first pore, 411 and second pore 421 is down
Frustum cone structure.
In the present embodiment, the first filter 41 and the second filter 42 are with stainless steel, nickel, aluminium, Parylene etc.
It is made for raw material.First pore, 411 and second pore 421 is formed with micron size.First pore 411 of micron size
It can be formed by using the etching or galvanoplastics of microelectromechanical-systems technology with the second pore 421.This first filter
411 and second filter 421 will not be deformed due to the pressure of the marrow mixed liquor of flowing or marrow mixed liquor.
The stem cell tissue collecting bottle leads in use, by the connection direct collecting device of human stem cell of third conduit 54
It crosses the syringe 55 to extract collected marrow mixed liquor to the bottle 1, first filter is equipped in the bottle 1
41 and second filter 42, set first filter 41 can filter marrow bulky grain, the marrow bulky grain filtered stays in
In first filter 41, the second set filter 42 can filter marrow little particle, and the marrow little particle filtered passes through institute
It states the second filter 42 to flow in lower bottle body 1, required stem cell stays between first filter 41 and the second filter 42
In set intermediate inner bottle 3, the intermediate inner bottle 3 is threadedly coupled between upper bottle body 11 and lower bottle body 12, passes through rotation
Upper bottle body 11 and lower bottle body 12 can take out the intermediate inner bottle 3 for storing stem cell, and what is stored in the intermediate inner bottle 3 is dry
Cell is acquired for other storage devices or collecting device, after use, can respectively be washed lower bottle body 12 and intermediate inner bottle 3
It washs, sterilizing, after the upper bottle body 11 dismantles the conduit tube component in opening 2, upper bottle body 11 and the second filter 42 is divided
Not Xi Di, sterilizing, disinfection after the completion of re-assembly collecting bottle in case next time use.
The utility model is simple in structure, and operation is easy, and the opening 2 is equipped with syringe 55 by guide-tube structure, using note
Emitter differential pressure principle carries out the acquisition of stem cell;The bottle 1 of setting can preserve blood flow, the set first filtering temporarily
Device 41 can filter marrow bulky grain, and the second set filter 42 can filter marrow little particle, the first filter 41
And second stem cell that can be arrived with store collected of intermediate inner bottle 3 set between filter 42, the intermediate inner bottle 3 with it is upper
It is threadedly coupled between bottle 11 and lower bottle body 12, can will be stored in stem cell by rotating upper bottle body 11 and lower bottle body 12
Between inner bottle 3 take out, the utility model makes swift to operate and convenient for disassembly and assembly.
The above description is only a preferred embodiment of the present invention, therefore all according to described in the utility model patent application range
The equivalent change or modification done of structure, feature and principle, be included in the scope of the utility model patent application.
Claims (7)
1. a kind of stem cell tissue collecting bottle, it is characterised in that:Including bottle (1), opening (2), intermediate inner bottle (3) and filtering
Part (4), bottle (1) upper end are equipped with the opening (2), filtration members (4), the opening (2) are equipped among the bottle (1)
It is equipped with, conduit connector sleeve (50), the conduit connector sleeve (50) connects the first conduit (51) one end, first conduit (51)
The other end connects a threeway pullover (52), and described other two pullover of threeway pullover (52) is separately connected the second conduit (53) and the
Three conduits (54), second conduit (53) connect with syringe (55), and third conduit (54) the connection human stem cell is adopted
Acquisition means;The filtration members (4) include first filter (41) and the second filter (42), and the first filter (41) is placed in
The top of second filter (42), the bottle (1) are divided into upper bottle body (11) and lower bottle body (12), the intermediate inner bottle
(3) it is nested in the upper bottle body (11) and lower bottle body (12), intermediate inner bottle (3) bottom is equipped with second filter
(42), it is equipped with first filter (41) in the upper bottle body (11), interior spiral shell is equipped in the upper bottle body (11) and lower bottle body (12)
Line (13), the intermediate inner bottle (3) are externally provided with and the internal thread (13) matched external screw thread (14), the first filter
(41) several first pores (411) are equipped with, second filter (42) is equipped with the second pore (421), and described first is thin
The diameter in hole (411) is more than stem cell diameter, and the diameter of second pore (421) is less than stem cell diameter.
2. a kind of stem cell tissue collecting bottle according to claim 1, it is characterised in that:First conduit (51) and
Adjuster (56) is respectively equipped on three conduits (54).
3. a kind of stem cell tissue collecting bottle according to claim 1, it is characterised in that:It is equipped in the lower bottle body (12)
Step (121), the step (121) support the intermediate inner bottle (3).
4. a kind of stem cell tissue collecting bottle according to claim 1, it is characterised in that:Intermediate inner bottle (3) institute
If external screw thread (14) be located at the both ends of the intermediate inner bottle (3), the middle section of the intermediate inner bottle (3) is equipped with scale
Table (31).
5. a kind of stem cell tissue collecting bottle according to claim 1, it is characterised in that:The first filter (41) sets
The top of set internal thread (13) in the upper bottle body (11), the upper bottle body (11) is interior to be equipped with step (111), the step
(111) first filter (41) is supported.
6. a kind of stem cell tissue collecting bottle according to claim 1, it is characterised in that:Second filter (42) with
The intermediate inner bottle (3) is integrated.
7. a kind of stem cell tissue collecting bottle according to claim 1, it is characterised in that:First pore (411) with
Second pore (421) is inverted round stage structure.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201721881994.8U CN207918842U (en) | 2017-12-28 | 2017-12-28 | A kind of stem cell tissue collecting bottle |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201721881994.8U CN207918842U (en) | 2017-12-28 | 2017-12-28 | A kind of stem cell tissue collecting bottle |
Publications (1)
Publication Number | Publication Date |
---|---|
CN207918842U true CN207918842U (en) | 2018-09-28 |
Family
ID=63615562
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201721881994.8U Expired - Fee Related CN207918842U (en) | 2017-12-28 | 2017-12-28 | A kind of stem cell tissue collecting bottle |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN207918842U (en) |
-
2017
- 2017-12-28 CN CN201721881994.8U patent/CN207918842U/en not_active Expired - Fee Related
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
GR01 | Patent grant | ||
GR01 | Patent grant | ||
CF01 | Termination of patent right due to non-payment of annual fee | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20180928 |