CN207913273U - A kind of taxol extraction element - Google Patents

A kind of taxol extraction element Download PDF

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Publication number
CN207913273U
CN207913273U CN201721854084.0U CN201721854084U CN207913273U CN 207913273 U CN207913273 U CN 207913273U CN 201721854084 U CN201721854084 U CN 201721854084U CN 207913273 U CN207913273 U CN 207913273U
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CN
China
Prior art keywords
tank body
fixedly connected
shaft
agitating shaft
extraction element
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Expired - Fee Related
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CN201721854084.0U
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Chinese (zh)
Inventor
彭程
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Northwest Minzu University
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Northwest Minzu University
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Priority to CN201721854084.0U priority Critical patent/CN207913273U/en
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Publication of CN207913273U publication Critical patent/CN207913273U/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Abstract

The utility model discloses a kind of taxol extraction elements, including tank body, condensation head and agitating shaft, inner tank wall is fixedly connected with separating plate, the separating plate other end is fixedly connected with drainage plate, tank body upper surface is fixedly embedded at several two rows of condensation heads, and condensation head is fixedly connected with several radiating fins on tank body upper section outer wall;Lower part is fixedly connected with two groups of shaft seats in the tank body, the agitating shaft is rotatably connected on respectively on two groups of shaft seats, agitating shaft is fixedly connected with stirring fan plate in shaft seat centre position, transmission gear has been fixedly connected on agitating shaft, it is also rotatablely connected there are two transmission shaft in agitating shaft top position on tank body rear wall, the front side end of transmission shaft has been fixedly connected with partial gear, partial gear engages connection with two transmission gears respectively, the utility model change of current is efficient, extraction effect is good, condensation is simple small and exquisite, and extracting solution can back and forth be utilized, reduce extracting solution consumption.

Description

A kind of taxol extraction element
Technical field
The utility model is related to a kind of extraction equipment, specifically a kind of taxol extraction element.
Background technology
Taxol is the two mushroom class compound of tricyclic separated from Chinese yew genus plants earliest, is after adriamycin and suitable The anti-cancer drugs of hottest point after platinum.There is taxol complicated chemical constitution, molecule to constitute two mushroom cores, molecule by 3 main rings In there is 11 chiral centres and the multiple substituent groups, parent cyclic moiety to be a complicated tetracyclic ring system, there are many functional group and Stereochemical characteristics.Molecular formula C47H51NO14, molecular weight 853.92.Tagging shows that taxol is bonded only to polymerize Micro-pipe on, not with unpolymerized tubulin dimerization precursor reactant.It can be accumulated in the cell after cell contact taxol a large amount of Micro-pipe, the accumulation of these micro-pipes disturb the various functions of cell, cell division are especially made to stop at m period, block The proper splitting of cell.By II-III clinical research, taxol is primarily adapted for use in oophoroma and breast cancer, to lung cancer, large intestine Cancer, melanoma, incidence cancer, lymthoma, brain tumor also have certain curative effect, purple as a kind of cancer treatment drugs of costliness The extraction of China fir alcohol lives through multiple reform, and wherein ultrasonic extraction is exactly the efficient extracting method of one of which.Current is super The mixing that sound wave extraction method carries out material using longitudinal stirring blade is extracted with can adequately contact ultrasonic wave, but It is that oscillator is generally mounted to two side position of tank body upper end, the material of ectonexine is handed in conventional central shaft type stirring now It is poor to change effect so that exert a certain influence to the extraction of part medicinal material, be intended to obtain higher recovery rate need to expend compared with Long time waits for ectonexine material to be sufficiently mixed exchanges, in addition, current extraction is disposable material extractant put into after It is together discharged, to ensure extraction effect, extracting solution generally requires largely to add, and guarantee will not can not because extracting solution is fully loaded Extraction, if things go on like this, causes prodigious waste;Further more, heating component is had to promote the current extractor polygamy of extraction efficiency, To avoid excessive extracting solution Influence of Evaporation extraction effect, polygamy steams extracting solution for equipment such as condenser and oil water separators at present Vapour is condensed the recycling squeezed into realize extracting solution again so that the floor space of complete equipment is very big, while pipeline knot Structure etc. is also more complicated, and equipment and the use cost in soil are increased for medium-sized and small enterprises.
Utility model content
It is mentioned above in the background art to solve the purpose of this utility model is to provide a kind of taxol extraction element Problem.
To achieve the above object, the utility model provides the following technical solutions:
A kind of taxol extraction element, including tank body, condensation head and agitating shaft, the tank body lower end are fixedly connected with branch Foot, outlet valve and inlet valve are respectively equipped at tank body lower end and upper end center, and tank body upper end is fixedly embedded at several ultrasonic waves shakes Stick is swung, tank wall is also fixedly connected with oily hot jacket, and oily hot jacket is equipped with oil filler and oil discharge outlet, is also fixedly connected in oily hot jacket There are several electrical bars, the inner tank wall to be fixedly connected with separating plate in tank body upper position, the separating plate is by metal frame Frame and the nylon membrane composition between being located therein, the separating plate other end are fixedly connected with drainage plate, and tank body upper surface is fixedly embedded at Several two rows of condensation heads, condensation head is hollow-core construction and inside is negative pressure state, and the inner wall for condensing head is covered with imbibition Core, condensation head are fixedly connected with several radiating fins on tank body upper section outer wall;Lower part is fixedly connected in the tank body Two groups of shaft seats, the agitating shaft is rotatably connected on respectively on two groups of shaft seats and it is also fixedly connected with torsion between shaft seat Spring, agitating shaft are fixedly connected with stirring fan plate in shaft seat centre position, transmission gear, tank body have been fixedly connected on agitating shaft It is also rotatablely connected there are two transmission shaft in agitating shaft top position on rear wall, the front side end of transmission shaft has been fixedly connected with endless All gear, partial gear engage connection with two transmission gears respectively, and the rear side end of transmission shaft has been respectively fixedly connected with actively Belt pulley and driving pulley, drive pulley are sequentially connected with driving pulley, and drive pulley is also driven with decelerating motor Connection.
As further program of the utility model:The condensation head is respectively positioned on separating plate and draws flitch boundary position.
As the utility model further scheme:Acetone is filled in the condensation head.
As the utility model further scheme:The oil hot jacket is coated on the left and right sidewall and front side wall of tank body On.
As the utility model further scheme:The process of described two stirring fan plates is opposite.
As the utility model further scheme:It lifts and is extremely prescribed a time limit with ultrasonic oscillation device not on the stirring fan plate Contact.
Compared with prior art, the utility model has the beneficial effects that:The reciprocating and staggered of plate is fanned by stirring to agitate so that Raw material can carry out the reciprocal flowing exchange in efficiently left and right in tank body, and central shaft stirring-type more now is compared to the flowing between raw material It is more rapid efficient to change layer, high efficiency extraction can be carried out to whole raw materials, improves due to ultrasonic wave stops and decays to former at center Material extraction is not thorough the low disadvantage of efficiency, practicality and high efficiency;Rapid cooling is carried out using the condensation head of liquid heat pipe principle so that with Contact solvent vapo(u)r can fast cooling condense and fall after rise, save equipment cost and floor space, it is convenient and practical, lead to simultaneously Taxol and extracting solution are carried out initial gross separation by the UF membrane principle for crossing separating plate, and purer extracting solution is fallen by separating plate Under, it ensure that internal solvent amount, extractant injected volume can be reduced, it is economical and practical.
Description of the drawings
Fig. 1 is a kind of main structure diagram of taxol extraction element.
Fig. 2 is a kind of right side structural representation of taxol extraction element.
Specific implementation mode
The technical solution of this patent is described in more detail With reference to embodiment.
Please refer to Fig.1-2, a kind of taxol extraction element, including tank body 1, condensation head 2 and agitating shaft 3, under the tank body 1 End is fixedly connected with stabilizer blade 4, outlet valve 5 and inlet valve 6 is respectively equipped at 1 lower end of tank body and upper end center, 1 upper end of tank body is fixed Several ultrasonic oscillation sticks 7 are embedded with, 1 side wall of tank body is also fixedly connected with oily hot jacket 8, and oily hot jacket 8 is equipped with oil filler 9 and row Hydraulic fluid port 10, is also fixedly connected with several electrical bars 11 in oily hot jacket 8, and 1 inner wall of the tank body connects 1 top position of tank body is fixed It is connected to separating plate 12, nylon membrane of the separating plate 12 by metal framework and between being located therein forms, and 12 other end of separating plate is solid Surely be connected with drainage plate 13,1 upper surface of tank body is fixedly embedded at several two rows of condensation heads 2, condensation head 2 be hollow-core construction and Inside is negative pressure state, and the inner wall of condensation head 2 is covered with liquid-sucking core 14, and condensation head 2 is fixed on 1 upper section outer wall of tank body Several radiating fins 15 are connected with, condenses and is filled with acetone in head 2, condensation head 2 can be to evaporating using liquid heat pipe principle Mixed vapour be quickly cooled down, it is cooling after mixing drop fallen from condensation head 2, condensation head 2 be respectively positioned on separating plate 12 with Draw flitch boundary position, so certifiable drop can be fallen on separating plate 12, pass through the UF membrane of the nylon membrane of separating plate 12 Principle, by most of taxol blocking accumulation therein, and other extracting solutions and taxane then fall progress by nylon membrane It extracts again, improves the extraction effect of extracting solution, outstanding extraction effect, economic ring are can be obtained by a small amount of extracting solution It protects;Lower part is fixedly connected with two groups of shaft seats 16 in the tank body 1, and the agitating shaft 3 is rotatably connected on two groups of shaft seats respectively On 16 and it is also fixedly connected with torsional spring 17 between shaft seat 16, and agitating shaft 3 is fixedly connected in 16 centre position of shaft seat Plate 18 is fanned in stirring, has been fixedly connected with transmission gear 19 on agitating shaft 3, has also been turned in 3 top position of agitating shaft on 1 rear wall of tank body Dynamic connection is there are two transmission shaft 20, and the front side end of transmission shaft 20 has been fixedly connected with partial gear 21, and partial gear 21 divides Connection is not engaged with two transmission gears 19, the rear side end of transmission shaft 20 has been respectively fixedly connected with drive pulley 22 and transmission skin Belt wheel, drive pulley 22 are sequentially connected with driving pulley, and drive pulley 22 is also sequentially connected with decelerating motor, and two are stirred Mix the process of fan plate 18 on the contrary, namely stirring fan plate 18 in side when being lifting status, another is crouches down state, and its torsional spring 17 It plays negative direction also to answer on the contrary, it engages period and should be staggered simultaneously, also as following working condition:The transmission of side stirring fan plate 18 When gear 19 is detached from partial gear 21, quick bullet is counter to agitate, and the fan of other side stirring at this time plate 18 should still be the slow of engagement Slow swing state, then when another stirring fan plate 18 is detached from that quick bullet is counter to agitate, it is then to nibble that original, which is detached from stirring fan plate 18, Rotary state is closed, so that two stirring fan plates 18 is staggeredly agitated so that material can carry out the exchange of stirring rapidly and efficiently, more existing Modern central shaft stirring-type changes that layer is more rapid efficiently to promote extraction effect compared to the flowing between raw material, to avoid collision damage It is bad, it lifts on stirring fan plate 18 and is not contacted with ultrasonic oscillation device in limited time extremely, to avoid oily hot jacket high temperature from influencing the transmission at the back side Structure, oily hot jacket are coated in the left and right sidewall and front side wall of tank body 1.
The better embodiment of this patent is explained in detail above, but this patent is not limited to above-mentioned embodiment party Formula, one skilled in the relevant art within the scope of knowledge, can also be under the premise of not departing from this patent objective It makes a variety of changes.

Claims (6)

1. a kind of taxol extraction element, including tank body (1), condensation head (2) and agitating shaft (3), tank body (1) lower end are fixed It is connected with stabilizer blade (4), outlet valve (5) and inlet valve (6), tank body (1) upper end are respectively equipped at tank body (1) lower end and upper end center Several ultrasonic oscillation sticks (7) are fixedly embedded at, tank body (1) side wall is also fixedly connected with oily hot jacket (8), is set on oily hot jacket (8) There are oil filler (9) and oil discharge outlet (10), is also fixedly connected with several electrical bars (11) in oily hot jacket (8), which is characterized in that described Tank body (1) inner wall has been fixedly connected with separating plate (12) in tank body (1) upper position, the separating plate (12) by metal framework and Nylon membrane composition between being located therein, separating plate (12) other end are fixedly connected with drainage plate (13), and tank body (1) upper surface is fixed Being embedded with two rows, several condense heads (2), and condensation head (2) is hollow-core construction and inside is negative pressure state, condenses the interior of head (2) Wall is covered with liquid-sucking core (14), and condensation head (2) is fixedly connected with several radiating fins on tank body (1) upper section outer wall (15);The interior lower part of the tank body (1) is fixedly connected with two groups of shaft seats (16), and the agitating shaft (3) is rotatably connected on two respectively On group shaft seat (16) and it is also fixedly connected with torsional spring (17) between shaft seat (16), and agitating shaft (3) is in shaft seat (16) Centre position is fixedly connected with stirring fan plate (18), has been fixedly connected with transmission gear (19) on agitating shaft (3), after tank body (1) It is also rotatablely connected there are two transmission shaft (20) in agitating shaft (3) top position on side wall, the front side end of transmission shaft (20) is fixed It is connected with partial gear (21), partial gear (21) engages connection, transmission shaft (20) with two transmission gears (19) respectively Rear side end be respectively fixedly connected with drive pulley (22) and driving pulley, drive pulley (22) is passed with driving pulley Dynamic connection, drive pulley (22) are also sequentially connected with decelerating motor.
2. a kind of taxol extraction element according to claim 1, which is characterized in that the condensation head (2) is respectively positioned on point From plate (12) and draw flitch boundary position.
3. a kind of taxol extraction element according to claim 1, which is characterized in that filled in the condensation head (2) There is acetone.
4. a kind of taxol extraction element according to claim 1, which is characterized in that the oil hot jacket is coated on tank body (1) in left and right sidewall and front side wall.
5. a kind of taxol extraction element according to claim 1, which is characterized in that the process of two stirring fan plates (18) On the contrary.
6. a kind of taxol extraction element according to claim 1, which is characterized in that lifted on the stirring fan plate (18) It is not contacted with ultrasonic oscillation device in limited time extremely.
CN201721854084.0U 2017-12-27 2017-12-27 A kind of taxol extraction element Expired - Fee Related CN207913273U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201721854084.0U CN207913273U (en) 2017-12-27 2017-12-27 A kind of taxol extraction element

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201721854084.0U CN207913273U (en) 2017-12-27 2017-12-27 A kind of taxol extraction element

Publications (1)

Publication Number Publication Date
CN207913273U true CN207913273U (en) 2018-09-28

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110064226A (en) * 2019-04-25 2019-07-30 桐城市红豆杉生态农林科技有限公司 It is a kind of to impregnate taxol extractor by the ultrasonic wave of raw material of Chinese yew

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110064226A (en) * 2019-04-25 2019-07-30 桐城市红豆杉生态农林科技有限公司 It is a kind of to impregnate taxol extractor by the ultrasonic wave of raw material of Chinese yew

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CF01 Termination of patent right due to non-payment of annual fee
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Granted publication date: 20180928

Termination date: 20191227