CN207828314U - Module mechanism and PCR gene amplification instrument - Google Patents
Module mechanism and PCR gene amplification instrument Download PDFInfo
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- CN207828314U CN207828314U CN201721925804.8U CN201721925804U CN207828314U CN 207828314 U CN207828314 U CN 207828314U CN 201721925804 U CN201721925804 U CN 201721925804U CN 207828314 U CN207828314 U CN 207828314U
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Abstract
A kind of module mechanism of the utility model offer and PCR gene amplification instrument, are related to gene-amplificative instrament technical field.The module mechanism includes：Babinet, it is the accommodating chamber of open end that babinet, which has one end,；Component is jacked, jacking component is set to one end far from the open end of accommodating chamber；Specimen holder, specimen holder are rotationally arranged at the side towards open end of jacking component；Heating component, heating component be set to jacking component towards open end side and opposite jacking component fix, specimen holder is located at the side of the separate jacking component of heating component, the side of the separate jacking component of heating component forms multiple equally distributed heating zones, and heating element is both provided in each heating zone；And control assembly, control assembly are located at the side towards open end of jacking component, control assembly is corresponded for controlling specimen holder with heating zone.The module mechanism it is reasonable for structure, highly practical, heating, cooling effect is good.
Description
Technical field
The utility model is related to gene-amplificative instrament technical fields, in particular to a kind of module mechanism and pcr gene
Amplification instrument.
Background technology
Round pcr generally refers to PCR, and PCR is a kind of specific for amplifying amplification
The Protocols in Molecular Biology of DNA fragmentation, it is considered as the special DNA replication dna of in vitro.The feature of PCR maximums is that energy will be micro-
The DNA of amount significantly increases.Therefore, round pcr is in phase in fields such as microbiology, hereditary disease, oncology and medical jurisprudence
Work as consequence.
Round pcr is made of denaturation-fundamental reaction step of annealing-extension three, it is then desired to be carried out repeatedly to sample
Heating, cooling processing, but the heating, cooling effect of the module mechanism of current PCR gene amplification instrument is bad, influences working efficiency.
Utility model content
The purpose of this utility model is to provide a kind of module mechanism, the module mechanism it is reasonable for structure, it is highly practical, change
It has been apt to module mechanism heating and the bad problem of cooling-down effect in the prior art, meanwhile, also ensure working efficiency.
The another object of the utility model is to provide a kind of PCR gene amplification instrument, which has above-mentioned
The repertoire of module mechanism.
What the embodiments of the present invention were realized in：
A kind of module mechanism is applied to PCR gene amplification instrument, including：
Babinet, it is the accommodating chamber of open end that the babinet, which has one end,；
Component is jacked, the jacking component is set to one end far from the open end of the accommodating chamber；
Specimen holder, the specimen holder are rotationally arranged at the side of the direction open end of the jacking component；
Heating component, the heating component are set to the side of the direction open end of the jacking component and opposite institute
It states jacking component to fix, the specimen holder is located at the side far from the jacking component of the heating component, the heating group
The side far from the jacking component of part forms multiple equally distributed heating zones, is both provided with and adds in each heating zone
Thermal element；With
Control assembly, the control assembly are located at the side of the direction open end of the jacking component, the control
Component is corresponded for controlling the specimen holder with the heating zone.
In addition, according to the module mechanism that the utility model embodiment provides, there can also be following additional technical characteristic：
In the utility model optional embodiment, the module mechanism further includes：
End cap, the end cap are matched with the open end of the babinet to open or close the opening of the accommodating chamber
End.
In the utility model optional embodiment, the module mechanism further includes：
Support plate, the support plate are set between the jacking component and the control assembly, and the support plate is used for
The control assembly is supported.
In the utility model optional embodiment, the jacking component includes at least three cylinders, the court of the support plate
To the side of the jacking component formed with the one-to-one location hole of the cylinder, it is described fixed that the piston rod of the cylinder stretches into
It is connect in the hole of position and with the contacted inner surfaces of the location hole.
In the utility model optional embodiment, cushion pad is provided in the location hole, the cushion pad is located at described
Between one end and the piston rod of the cylinder far from the cylinder of location hole.
In the utility model optional embodiment, the control assembly includes：
Stepper motor, the stepper motor are fixedly mounted in the support plate；With
Angle dispenser, the angle dispenser be mounted on the support plate on, the input terminal of the angle dispenser with
The output shaft of the stepper motor is connected, the output end of the angle dispenser pass through the heating component and with the specimen holder
It is connected.
In the utility model optional embodiment, the module mechanism further includes：
Multiple support columns, the multiple support column is distributed in the peripheral surface of the output end of the angle dispenser, described more
One end of a support column is fixedly connected on the side far from the jacking component of the angle dispenser, the multiple support column
The other end be connected with the heating component.
In the utility model optional embodiment, the specimen holder is provided with multiple sample putting holes, and the sample is placed
Hole is stepped hole, and the stepped hole includes the first hole and the second hole, and the aperture in first hole is more than the aperture in second hole,
And relatively described second hole in first hole is far from the heating component.
In the utility model optional embodiment, the heating zone is configured to the groove towards the jacking component-recess,
The heating element is set in the groove.
The utility model embodiment also provides a kind of PCR gene amplification instrument comprising above-mentioned module mechanism.
The advantageous effect of the utility model embodiment is：The module mechanism it is simple and reasonable for structure, manufacturing cost is low, real
It is strong with property, due to that specimen holder can be jacked to the outside of accommodating chamber using jacking component so that its cooling-down effect is preferable, works as sample
Be conducive to its temperature rise effect when being placed in the accommodating chamber of relative closure, to improve work efficiency.
Description of the drawings
It, below will be to required use in embodiment in order to illustrate more clearly of the technical solution of the utility model embodiment
Attached drawing be briefly described, it should be understood that the following drawings illustrates only some embodiments of the utility model, therefore should not be by
Regard the restriction to range as, for those of ordinary skill in the art, without creative efforts, may be used also
To obtain other relevant attached drawings according to these attached drawings.
Fig. 1 is the structural schematic diagram for the module mechanism that the utility model embodiment provides；
Fig. 2 is the structural schematic diagram of support plate in Fig. 1；
Fig. 3 is the structural schematic diagram of specimen holder；
Fig. 4 is the structural schematic diagram of sample putting hole.
Icon：100- babinets；101- accommodating chambers；102- stage portions；103- ventilation holes；120- cylinders；130- support plates；
131- location holes；132- cushion pads；140- stepper motors；150- angle dispensers；160- heating components；The heating zones 161-；
170- support columns；180- specimen holders；The first holes 181-；The second holes 182-.
Specific implementation mode
It is new below in conjunction with this practicality to keep the purpose, technical scheme and advantage of the utility model embodiment clearer
Attached drawing in type embodiment, the technical scheme in the utility model embodiment is clearly and completely described, it is clear that is retouched
The embodiment stated is the utility model a part of the embodiment, instead of all the embodiments.Usually here described in attached drawing and
The component of the utility model embodiment shown can be arranged and be designed with a variety of different configurations.
Therefore, the detailed description of the embodiments of the present invention to providing in the accompanying drawings is not intended to limit requirement below
The scope of the utility model of protection, but it is merely representative of the selected embodiment of the utility model.Based in the utility model
Embodiment, the every other embodiment that those of ordinary skill in the art are obtained without creative efforts, all
Belong to the range of the utility model protection.
It should be noted that：Similar label and letter indicate similar terms in following attached drawing, therefore, once a certain Xiang Yi
It is defined, then it further need not be defined and explained in subsequent attached drawing in a attached drawing.
In the description of the present invention, it should be noted that the orientation of the instructions such as term "upper", "lower", "inner", "outside"
Or position relationship be based on the orientation or positional relationship shown in the drawings or the utility model product using when usually put
Orientation or positional relationship is merely for convenience of describing the present invention and simplifying the description, and does not indicate or imply the indicated dress
It sets or element must have a particular orientation, with specific azimuth configuration and operation, therefore should not be understood as to the utility model
Limitation.In addition, term " first ", " second " etc. are only used for distinguishing description, it is not understood to indicate or imply relatively important
Property.
In the description of the present invention, it should also be noted that, unless otherwise clearly defined and limited, term " is set
Set ", " installation ", " connected ", " connection " shall be understood in a broad sense, for example, it may be being fixedly connected, may be a detachable connection,
Or it is integrally connected；It can be mechanical connection, can also be electrical connection；It can be directly connected, intermediary can also be passed through
It is indirectly connected, can be the connection inside two elements.For the ordinary skill in the art, it can be managed with concrete condition
Solve the concrete meaning of above-mentioned term in the present invention.
In the present invention unless specifically defined or limited otherwise, fisrt feature is on or below second feature
It may include that the first and second features are in direct contact, can also not be to be in direct contact but pass through it including the first and second features
Between other characterisation contact.Moreover, fisrt feature is on second feature, top and above include fisrt feature the
Right over two features and oblique upper, or be merely representative of fisrt feature level height and be higher than second feature.Fisrt feature is in the second spy
Under sign, lower section and fisrt feature included below are immediately below second feature and obliquely downward, or are merely representative of fisrt feature level
Height is less than second feature.
Embodiment 1
Refering to fig. 1, the utility model embodiment provides a kind of module mechanism, which expands applied to pcr gene
In instrument, which includes babinet 100, jacking component, support plate 130, specimen holder 180, heating component 160 and control group
Part.
Wherein, the shape of the babinet 100 can be square column or cylindrical-shaped structure, in the present embodiment, shape
Preferably square column structure.
Refering to fig. 1, babinet 100 has accommodating chamber 101, and one end of the accommodating chamber 101 is open end, and the other end is closing
End, jacks component, specimen holder 180, heating component 160 and control assembly and is respectively positioned in the accommodating chamber 101 as a result,.
Refering to fig. 1, in the present embodiment, ventilation hole 103 is additionally provided on the side wall of the babinet 100.
In the present embodiment, which further includes end cap.
The open end has stage portion 102, which closes for covering at stage portion 102, so that the end cap can be opened
Or close accommodating chamber 101.
Wherein, stage portion 102 and end cap cooperate, and matching herein refer to, the shape of stage portion 102 and end cap
Shape is identical, size is adapted, i.e., when stage portion 102 is round, the shape of end cap is also circle, when the shape of stage portion 102
When shape is rectangle, the shape of end cap is also rectangle.
Refering to fig. 1, in the present embodiment, jacking component includes at least three cylinders 120.
At least three cylinders 120 are mounted on the bottom of accommodating chamber 101, and at least three cylinders 120 are evenly distributed on receiving
The bottom of the bottom of chamber 101, at least three cylinders, 120 vertically-mounted and opposite accommodating chamber 101 is fixed.
In the present embodiment, support plate 130 is to be set to the top of cylinder 120.Support plate 130 be used for heating component 160,
Control assembly and specimen holder 180 are supported.
Wherein, the shape of support plate 130 is indefinite, can be round, rectangle or other shapes, when its area should be less than
The lateral cross-sectional area of accommodating chamber 101, so that support plate 130 can be positioned in accommodating chamber 101.As a result, when cylinder 120 jacks
When, cylinder 120 can push support plate 130 to be moved towards the open end of accommodating chamber 101.
Referring to Fig.2, further, the side of the direction jacking component of support plate 130 is provided with to be corresponded with cylinder 120
Location hole 131.
One-to-one correspondence herein refers to that the quantity of location hole 131 is identical as the quantity of cylinder 120, the position of location hole 131
Also it is corresponded with the position of cylinder 120, which is arranged in the bottom side of support plate 130, and location hole 131 is preferably blind
Hole, and the top of the piston rod of cylinder 120 is stretched into location hole 131.
Since the location hole 131 uses blind hole so that location hole 131 is set in the top of the piston rod of cylinder 120, to
So that occurring relative displacement between support plate 130 and cylinder 120 in the horizontal direction, preferably make location hole 131 and cylinder 120
Piston rod is clearance fit.
Referring to Fig.2, in addition, the module mechanism further includes multiple cushion pads 132, the quantity and location hole of the cushion pad 132
131 quantity is identical.
The cushion pad 132 can be used rubber material and be made, and cushion pad 132 is arranged in location hole 131, and be located at location hole
Between one end and the piston rod of cylinder 120 of 131 separate cylinder 120, the shape of the shape and location hole 131 of cushion pad 132
Match.
In the present embodiment, control assembly is located at the side towards open end of support plate 130, i.e. control assembly is mounted on branch
On fagging 130.
Refering to fig. 1, specifically, control assembly includes stepper motor 140 and angle dispenser 150.
Wherein, stepper motor 140 is fixedly mounted in support plate 130, and angle dispenser 150 is also fixedly mounted on support plate
On 130, and angle dispenser 150 is disposed adjacent with stepper motor 140, output shaft and the angle dispenser 150 of stepper motor 140
Input terminal be connected and rotate synchronously, the output end of angle dispenser 150 passes through heating component 160 and is connected with specimen holder 180.
As a result, when stepper motor 140 works, the input terminal rotation of angle dispenser 150 is driven, and then drives angle
The output end of dispenser 150 rotates, so that the specimen holder 180 being connected with the output end of angle dispenser 150 rotates therewith.
In the present embodiment, the substantially plate-like structure of heating component 160, heating component 160 is mounted on angle dispenser 150
Side far from jacking component.
Refering to fig. 1, specifically, which further includes multiple support columns 170.
Multiple support columns 170 are distributed in the peripheral surface of the output end of angle dispenser 150, one end of multiple support columns 170
It is fixedly connected on the side of the separate jacking component of angle dispenser 150, the other end and heating component of multiple support columns 170
160 are connected, so that the fixation of 160 relative angle dispenser 150 of heating component.
In addition, one end of the support column 170 can also be connect with support plate 130, it can also realize that heating component 160 is opposite
The fixation of angle dispenser 150.
In the present embodiment, heating component 160 is located at the side towards open end of angle dispenser 150, wherein heating group
The side of the separate jacking component of part 160 forms multiple equally distributed heating zones 161, and the middle part of heating component 160 is provided with
One through-hole, so that the output end of angle dispenser 150 passes through.
Further, which is configured to the groove towards jacking component direction recess, and is arranged in the groove
There is heating element, wherein heating tube or electric heating coil can be used in heating element.It should be noted that multiple heating zones 161 can be set
Fixed different temperature is more conducive to pair when jacking component jacks specimen holder 180 to the outside of the open end of accommodating chamber 101
Specimen holder 180 realizes cooling, in addition, when being heated to specimen holder 180, it can be by 103 envelope of ventilation hole on 100 side wall of babinet
Close, when cooling down to specimen holder 180, then open the ventilation hole 103 on 100 side wall of babinet, to it is corresponding provide heating or
Person's cooling efficiency.
It is appreciated that specimen holder 180 is located at the top of heating zone 161, and in the present embodiment, specimen holder 180 and heating zone 161
It corresponds, under the action of control assembly, specimen holder 180 often rotates by a certain angle, and specimen holder 180 can be located therein one
The surface of a heating zone 161.
In the present embodiment, which can be used for holding test tubes, and multiple samples are provided on specimen holder 180 and are placed
Hole.
In conjunction with Fig. 3 and Fig. 4, wherein sample putting hole is stepped hole, which includes the first hole 181 and the second hole
182, the first hole 181 and the second hole 182 are interconnected, and the first hole 181 and the coaxial arrangement of the second hole 182.
The aperture in the first hole 181 is more than the aperture in the second hole 182, and 181 opposite second hole 182 of the first hole is far from heating group
Part 160, wherein test tube is i.e. for being placed in the first hole 181, since the second hole 182 is opposite with heating zone 161 below
It answers so that the heat generated by heating zone 161 can directly heat test tube, to improve the efficiency of heating surface.
To sum up, the module mechanism is reasonable for structure, and heating, cooling effect is good, and work efficiency is high.
Embodiment 2
The utility model embodiment is also provided in a kind of PCR gene amplification instrument, which includes above-mentioned
Module mechanism.
Whole effects with above-mentioned module mechanism in PCR gene amplification instrument.
The above descriptions are merely preferred embodiments of the present invention, is not intended to limit the utility model, for this
For the technical staff in field, various modifications and changes may be made to the present invention.It is all in the spirit and principles of the utility model
Within, any modification, equivalent replacement, improvement and so on should be included within the scope of protection of this utility model.
Claims (10)
1. a kind of module mechanism is applied to PCR gene amplification instrument, which is characterized in that including：
Babinet, it is the accommodating chamber of open end that the babinet, which has one end,；
Component is jacked, the jacking component is set to one end far from the open end of the accommodating chamber；
Specimen holder, the specimen holder are rotationally arranged at the side of the direction open end of the jacking component；
Heating component, the heating component are set to the side of the direction open end of the jacking component and the relatively described top
It rises component to fix, the specimen holder is located at the side far from the jacking component of the heating component, the heating component
Side far from the jacking component forms multiple equally distributed heating zones, and heating unit is both provided in each heating zone
Part；With
Control assembly, the control assembly are located at the side of the direction open end of the jacking component, the control assembly
It is corresponded with the heating zone for controlling the specimen holder.
2. module mechanism according to claim 1, which is characterized in that the module mechanism further includes：
End cap, the end cap are matched with the open end of the babinet to open or close the open end of the accommodating chamber.
3. module mechanism according to claim 1, which is characterized in that the module mechanism further includes：
Support plate, the support plate are set between the jacking component and the control assembly, and the support plate is used for institute
Control assembly is stated to be supported.
4. module mechanism according to claim 3, which is characterized in that the jacking component includes at least three cylinders, institute
The side for stating the direction jacking component of support plate is formed and the one-to-one location hole of the cylinder, the piston of the cylinder
Bar is stretched into the location hole and is connect with the contacted inner surfaces of the location hole.
5. module mechanism according to claim 4, which is characterized in that cushion pad is provided in the location hole, it is described slow
Punching pad is between one end and the piston rod of the cylinder far from the cylinder of the location hole.
6. module mechanism according to claim 3, which is characterized in that the control assembly includes：
Stepper motor, the stepper motor are fixedly mounted in the support plate；With
Angle dispenser, the angle dispenser be mounted on the support plate on, the input terminal of the angle dispenser with it is described
The output shaft of stepper motor is connected, the output end of the angle dispenser pass through the heating component and with the specimen holder phase
Even.
7. module mechanism according to claim 6, which is characterized in that the module mechanism further includes：
Multiple support columns, the multiple support column are distributed in the peripheral surface of the output end of the angle dispenser, the multiple branch
One end of dagger be fixedly connected on the angle dispenser far from it is described jacking component side, the multiple support column it is another
One end is connected with the heating component.
8. module mechanism according to claim 6, which is characterized in that the specimen holder is provided with multiple sample putting holes,
The sample putting hole is stepped hole, and the stepped hole includes the first hole and the second hole, and the aperture in first hole is more than described
The aperture in the second hole, and relatively described second hole in first hole is far from the heating component.
9. module mechanism according to claim 1, which is characterized in that the heating zone is configured to towards the jacking component
The groove of recess, the heating element are set in the groove.
10. a kind of PCR gene amplification instrument, which is characterized in that including claim 1-9 any one of them module mechanisms.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201721925804.8U CN207828314U (en) | 2017-12-29 | 2017-12-29 | Module mechanism and PCR gene amplification instrument |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201721925804.8U CN207828314U (en) | 2017-12-29 | 2017-12-29 | Module mechanism and PCR gene amplification instrument |
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| Publication Number | Publication Date |
|---|---|
| CN207828314U true CN207828314U (en) | 2018-09-07 |
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ID=63391299
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| CN201721925804.8U Active CN207828314U (en) | 2017-12-29 | 2017-12-29 | Module mechanism and PCR gene amplification instrument |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114350760A (en) * | 2022-01-12 | 2022-04-15 | 浙江正合谷生物科技有限公司 | PCR amplification instrument and method for nucleic acid on-site temperature-variable amplification |
-
2017
- 2017-12-29 CN CN201721925804.8U patent/CN207828314U/en active Active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114350760A (en) * | 2022-01-12 | 2022-04-15 | 浙江正合谷生物科技有限公司 | PCR amplification instrument and method for nucleic acid on-site temperature-variable amplification |
| CN114350760B (en) * | 2022-01-12 | 2024-04-12 | 浙江正合谷生物科技有限公司 | PCR amplification instrument and amplification method for on-site variable-temperature amplification of nucleic acid |
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