CN207785317U - A kind of endocranium reparation sticking patch - Google Patents
A kind of endocranium reparation sticking patch Download PDFInfo
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- CN207785317U CN207785317U CN201720686605.XU CN201720686605U CN207785317U CN 207785317 U CN207785317 U CN 207785317U CN 201720686605 U CN201720686605 U CN 201720686605U CN 207785317 U CN207785317 U CN 207785317U
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- endocranium
- sticking patch
- short silk
- repair
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Abstract
A kind of endocranium reparation sticking patch, is three-layer composite structure, includes membranaceous impervious barrier, repair layer and netted lamella successively from outside to inside, and the outer surface of the netted lamella is contacted with membranaceous impervious barrier inner surface, and inner surface covers repair layer;It is characterized in that the netted lamella is made of basal layer and adhesive layer, the basal layer is woven by filamentary material, the adhesive layer is made of the short silk for being clouded in basal layer inner surface, and the fixing end of the short silk is fixed on basal layer inner surface, and the free end of short silk is formed by bending barb.
Description
Technical field
The utility model belongs to field of biomedical materials, and in particular to a kind of endocranium reparation sticking patch.
Background technology
Cranial surgery operation of opening cranium patient has 10-15% to need artificial dura mater to repair dura defect, to prevent simultaneously
Send out the generation of disease.Therefore suitable endocranium repair materials are conducted a research to meet clinical needs, is always that neurosurgery is concerned about
The problem of.
Although not will produce using autologous tissue's Hard meninges in reconstruction convenient material drawing and unfavorable or harmful immunological rejection,
Infection will not be transmitted, however the incidence of its early postoperation leakage of cerebrospinal and hypohydrops is still higher, easily leads to adhesion etc.
Complication.
As dural substitutes there is good biocompatibility, the country clinically often to make using biologic replacement materials
With bovine pericardium, sheep pericardium, year peritonaeum, pig peritonaeum, mesenterium etc. replace dura mater, with it is safe to use it is effective, more flexible, be easy to
The advantages that operating, derive from a wealth of sources, is cheap.However, its also have simultaneously cause adhesion, it is not easy to maintain, be not easy to sterilize, have can
The defects of immune response can occur.Though natural material such as natural collagen protein has good flexibility and elasticity, it is easy to absorb
The advantages that, but bioprotein film pastes not tight, the easy outer hydrops of formation meninx;Additionally due to bioprotein film is absorbable, in the later stage
Easily lacked the protection to meninx when making skull repairing by absorption, is easy to accidentally injure brain tissue.
As technology develops, artificial synthesized resorbable polymeric materials are also gradually applied to surgery minimal invasive and repair, such as
Polyvinyl alcohol, polyethylene glycol, polycaprolactone and poly lactic-co-glycolic acid etc., although these materials elasticity and intensity can meet
Demand, but biocompatibility is relatively weak, it is also possible to cause localized liquid accumulation, aseptic inflammation etc..Thus provide one kind
Degradable high polymer material and natural material advantage can be integrated, endocranium repair sticking patch become it is urgently to be resolved hurrily in the prior art
The problem of.
Utility model content
To solve aforementioned technical problem, the utility model uses following technical scheme:Provide a kind of endocranium reparation
Sticking patch is three-layer composite structure, includes antiseepage film layer, middle layer and repair layer, the appearance of the middle layer successively from outside to inside
Face is contacted with antiseepage last layer inner surface, and inner surface covers repair layer;It is characterized in that the middle layer is by substrate web and adhesive layer group
At the substrate web is woven by filamentary material, and the adhesive layer is made of the short silk for being clouded in substrate web inner surface, described
The fixing end of short silk is fixed on basal layer inner surface, and the free end of short silk is formed by bending barb.The thickness of the antiseepage film layer is
0.05-0.5mm, the total interlayer thickness are 0.1~1mm, and the base layer thickness is 0.05-0.5mm.
The endocranium repairs sticking patch, it is characterized in that the antiseepage film layer, middle layer are all made of degradable macromolecule
Material is made, and the repair layer is collagen or collagen composite material.
Endocranium provided by the utility model repairs sticking patch, using three-layer composite structure, using antiseepage film layer as outermost layer
Protective layer, prevent the exudation that intracerebral is tolerant, use the middle layer that substrate web and adhesive layer are combined, substrate web has one
Fixed elasticity, can improve and repair the adaptability that sticking patch changes cranium pressure, and adhesive layer is formed the short silk of barb by upright end
Composition can improve the adhesive ability of the repair layer of collagen material composition, to realize good protective effect,
It can be improved again to dural repair.
Description of the drawings
Fig. 1 is that the utility model provides a kind of structural schematic diagram of endocranium reparation sticking patch.
Specific implementation mode
A kind of endocranium provided by the utility model repairs sticking patch, is three-layer composite structure, includes anti-successively from outside to inside
Film layer 1, middle layer 2 and repair layer 3 are oozed, the outer surface of the middle layer is contacted with antiseepage last layer inner surface, and inner surface covering is repaiied
Cladding;The middle layer is made of substrate web 21 and adhesive layer 22, and the substrate web is woven by filamentary material, the attachment
Layer is made of the short silk for being clouded in substrate web inner surface, and the fixing end of the short silk is fixed on basal layer inner surface, short silk from
Barb is formed by bending by end.The thickness of the antiseepage film layer is 0.05-0.5mm, and the total interlayer thickness is 0.1~1mm,
The base layer thickness is 0.05-0.5mm.
The antiseepage film layer, middle layer are all made of degradable high polymer material and are made, and the repair layer is collagen
Or collagen composite material.Make middle layer degradable high polymer material be poly lactic coglycolic acid (PG910) with
Polydioxanone, the degradable high polymer material for making antiseepage film layer are that polydioxanone prepares antiseepage film layer.
The application method that the endocranium repairs sticking patch is as follows
1) dural patch to match depending on dura defect size clip size shape
2) by repair layer towards brain tissue, silk thread key approximation suture is first used,
3) antiseepage film layer is made into the continuous suture of endocranium with defect endocranium edge with absorbable filament or tight interruption subtracts
Open suture.
Claims (2)
- It is three-layer composite structure 1. a kind of endocranium repairs sticking patch, includes antiseepage film layer, middle layer and reparation successively from outside to inside Layer, the outer surface of the middle layer are contacted with antiseepage last layer inner surface, and inner surface covers repair layer;It is characterized in that the middle layer It is made of substrate web and adhesive layer, the substrate web is woven by filamentary material, and the adhesive layer is by being clouded in substrate web The short silk on surface forms, and the fixing end of the short silk is fixed on basal layer inner surface, and the free end of short silk is formed by bending barb, institute The thickness for stating antiseepage film layer is 0.05-0.5mm, and the total interlayer thickness is 0.1~1mm, and the base layer thickness is 0.05- 0.5mm。
- 2. a kind of endocranium as described in claim 1 repairs sticking patch, it is characterized in that the antiseepage film layer, middle layer are all made of Degradable high polymer material is made, and the repair layer is collagen or collagen composite material.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN201720686605.XU CN207785317U (en) | 2017-06-14 | 2017-06-14 | A kind of endocranium reparation sticking patch |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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CN201720686605.XU CN207785317U (en) | 2017-06-14 | 2017-06-14 | A kind of endocranium reparation sticking patch |
Publications (1)
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CN207785317U true CN207785317U (en) | 2018-08-31 |
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CN201720686605.XU Active CN207785317U (en) | 2017-06-14 | 2017-06-14 | A kind of endocranium reparation sticking patch |
Country Status (1)
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CN (1) | CN207785317U (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111330079A (en) * | 2020-03-31 | 2020-06-26 | 江苏白衣缘生物工程有限公司 | Artificial dura mater composite patch |
-
2017
- 2017-06-14 CN CN201720686605.XU patent/CN207785317U/en active Active
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111330079A (en) * | 2020-03-31 | 2020-06-26 | 江苏白衣缘生物工程有限公司 | Artificial dura mater composite patch |
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