CN207659422U - Bioreactor moves material device - Google Patents

Bioreactor moves material device Download PDF

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Publication number
CN207659422U
CN207659422U CN201721494495.3U CN201721494495U CN207659422U CN 207659422 U CN207659422 U CN 207659422U CN 201721494495 U CN201721494495 U CN 201721494495U CN 207659422 U CN207659422 U CN 207659422U
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China
Prior art keywords
pneumatic diaphragm
diaphragm valve
reservoir
feed liquid
culture medium
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Active
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CN201721494495.3U
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Chinese (zh)
Inventor
刘汉奇
许少迪
杨明
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SHANGHAI GAOJI BIOENGINEERING CO Ltd
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SHANGHAI GAOJI BIOENGINEERING CO Ltd
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Priority to CN201721494495.3U priority Critical patent/CN207659422U/en
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Abstract

The utility model is related to a kind of bioreactors to move material device, including reservoir, culture medium pneumatic diaphragm valve, steam pneumatic diaphragm valve, waste liquid pneumatic diaphragm valve, cleaning liquid interface and several retort feed liquid pneumatic diaphragm valves, reservoir is hollow structure, culture medium pneumatic diaphragm valve, steam pneumatic diaphragm valve, cleaning liquid interface and at least one retort feed liquid pneumatic diaphragm valve are connected to the upside of reservoir, and waste liquid pneumatic diaphragm valve and at least one retort feed liquid pneumatic diaphragm valve are connected to the downside of reservoir.The utility model can contamination-freely carry out bio-culture solution transfer, can realize the transfer of feed liquid between addition culture medium and differential responses tank, widely used, advantageously reduce cost.

Description

Bioreactor moves material device
Technical field
The utility model belongs to the technical field of reactor content transfer, and material dress is moved more particularly to a kind of bioreactor It sets.
Background technology
For pharmacy fermentation tank as technology makes into, ripe, fermentation tank operation volume often has 1000L or more or even 3000L, The big fermentation tank such as 5000L.Wherein, corresponding two-stage moves material culture transferring (materials such as cell/bacterium/culture medium), and especially volume is larger Fermentation tank moves and expects that the time is long, careless slightly, just contaminated to lead to the failure.
In actual production process, cross line is mostly used, material is moved with valve switch, pipeline complexity quantity is more, moves expects pipe Journey is long, easily causes microbiological contamination that fermentation is caused to fail.Fermentation failure is more than for company and delays the product supply time, and Directly contribute the great number economic loss that raw material are scrapped.There is customization Multichannel combination valve now, material sterility problems are moved though meeting, because Its is complicated, and time-consuming for single-minded design, and solid forging makes, and (high precision numerical control vehicle is needed for processing equipment is extremely rigorous Bed);And multiple valve hands over the phase long, price, and later stage replacement is cumbersome, is also used with regard to rare enterprise.
Invention content
The technical problem to be solved by the utility model is to provide a kind of bioreactors to move material device, effectively avoids moving and expect It pollutes, reduces cost.
Technical solution adopted by the utility model to solve its technical problems is providing a kind of bioreactor shifting material device, Including reservoir, culture medium pneumatic diaphragm valve, steam pneumatic diaphragm valve, waste liquid pneumatic diaphragm valve, cleaning liquid interface and several anti- Answer tank feed liquid pneumatic diaphragm valve, the reservoir is hollow structure, the culture medium pneumatic diaphragm valve, steam pneumatic diaphragm valve, Cleaning liquid interface and at least one retort feed liquid pneumatic diaphragm valve are connected to the upside of reservoir, the waste liquid pneumatic diaphragm valve It is connected to the downside of reservoir at least one retort feed liquid pneumatic diaphragm valve.
The reservoir is in integrally upper and lower symmetrical structure, and the hollow cavity inside reservoir is globoidal structure.
It is set on the upside of the reservoir and sets that there are two retort feed liquid gas there are one retort feed liquid pneumatic diaphragm valve, downside Dynamic diaphragm valve.
The cleaning liquid interface is the fast connection interface of clip.
Advantageous effect
In the present invention, by culture medium pneumatic diaphragm valve, steam pneumatic diaphragm valve, waste liquid pneumatic diaphragm valve, cleaning Liquid interface and retort feed liquid pneumatic diaphragm valve concentrated setting can carry out CIP before carrying out shifting material on reservoir to device Cleaning and steam sterilizing ensure that shifting material is pollution-free, can realize the transfer of feed liquid between addition culture medium and differential responses tank, use Way extensively, advantageously reduces cost.
Description of the drawings
Fig. 1 is the dimensional structure diagram of the utility model.
Fig. 2 is the positive structure schematic of the utility model.
Specific implementation mode
With reference to specific embodiment, the utility model is expanded on further.It should be understood that these embodiments are merely to illustrate this Utility model rather than limitation the scope of the utility model.In addition, it should also be understood that, in the content for having read the utility model instruction Later, those skilled in the art can make various changes or modifications the utility model, and such equivalent forms equally fall within this Shen It please the appended claims limited range.
A kind of bioreactor as depicted in figs. 1 and 2 moves material device, including reservoir 5, culture medium pneumatic diaphragm valve 1, Steam pneumatic diaphragm valve 2, waste liquid pneumatic diaphragm valve 6, cleaning liquid interface 4, A retort feed liquids pneumatic diaphragm valve 3, B retort material Hydraulic pneumatic diaphragm valve 7 and C retort feed liquids pneumatic diaphragm valve 8.
Reservoir 5 is hollow structure, whole symmetrical above and below, and the hollow cavity inside reservoir 5 is globoidal structure, is ensured in it Portion prevents hydrops without dead angle, and pollution is avoided to be detained.
Culture medium pneumatic diaphragm valve 1, steam pneumatic diaphragm valve 2, cleaning liquid interface 4 and A retort feed liquid pneumatic diaphragm valves It is connected to the upside of reservoir 5, cleaning liquid interface 4 is the fast connection interface of clip.Waste liquid pneumatic diaphragm valve 6, B retort feed liquids are pneumatic Diaphragm valve 7 and C retort feed liquids pneumatic diaphragm valve 8 are connected to the downside of reservoir 5.
The bioreactor, which moves, expects that the operation principle of device is:It cleaned, sterilized before each shifting material, share reservoir 5, by controlling different valves, it is connected to the pipeline of different directions, realizes that clean move is expected.Concrete operation step is as follows:
1, rotating wash bowl cleaning reservoir 5 and valve are connected by cleaning liquid interface 4;
2,2 input pure steam of steam pneumatic diaphragm valve is opened to sterilize to device inside;
3, respective valves are opened, A tanks can be carried out to B/C tanks shifting material or culture medium moves to B/C tanks or B tanks move to C tanks.

Claims (4)

1. a kind of bioreactor moves material device, including reservoir (5), culture medium pneumatic diaphragm valve (1), steam pneumatic diaphragm valve (2), waste liquid pneumatic diaphragm valve (6), cleaning liquid interface (4) and several retort feed liquid pneumatic diaphragm valves, it is characterised in that:It is described Reservoir (5) be hollow structure, the culture medium pneumatic diaphragm valve (1), steam pneumatic diaphragm valve (2), cleaning liquid interface (4) and At least one retort feed liquid pneumatic diaphragm valve is connected to the upside of reservoir (5), the waste liquid pneumatic diaphragm valve (6) and at least One retort feed liquid pneumatic diaphragm valve is connected to the downside of reservoir (5).
2. a kind of bioreactor according to claim 1 moves material device, it is characterised in that:The reservoir (5) is whole In upper and lower symmetrical structure, the internal hollow cavity of reservoir (5) is globoidal structure.
3. a kind of bioreactor according to claim 1 moves material device, it is characterised in that:The reservoir (5) it is upper Side, which is set, sets that there are two retort feed liquid pneumatic diaphragm valves there are one retort feed liquid pneumatic diaphragm valve, downside.
4. a kind of bioreactor according to claim 1 moves material device, it is characterised in that:The cleaning liquid interface (4) For the fast connection interface of clip.
CN201721494495.3U 2017-11-10 2017-11-10 Bioreactor moves material device Active CN207659422U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201721494495.3U CN207659422U (en) 2017-11-10 2017-11-10 Bioreactor moves material device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201721494495.3U CN207659422U (en) 2017-11-10 2017-11-10 Bioreactor moves material device

Publications (1)

Publication Number Publication Date
CN207659422U true CN207659422U (en) 2018-07-27

Family

ID=62938048

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201721494495.3U Active CN207659422U (en) 2017-11-10 2017-11-10 Bioreactor moves material device

Country Status (1)

Country Link
CN (1) CN207659422U (en)

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