CN207658395U - Biological sample transfer device - Google Patents

Biological sample transfer device Download PDF

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Publication number
CN207658395U
CN207658395U CN201721672278.9U CN201721672278U CN207658395U CN 207658395 U CN207658395 U CN 207658395U CN 201721672278 U CN201721672278 U CN 201721672278U CN 207658395 U CN207658395 U CN 207658395U
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China
Prior art keywords
sample
transfer
box
biological sample
manipulator
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Active
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CN201721672278.9U
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Chinese (zh)
Inventor
胡佳霖
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Base Biotechnology (Chengdu) Co.,Ltd.
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Vico Point (chengdu) Medical Robot Technology Co Ltd
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Abstract

The utility model discloses a kind of biological sample transfer devices, belong to biological sample access technique field, including transfer carriage, gripping and the manipulator for shifting sample transported walking mechanism, be connected in transhipment walking mechanism;It is provided with transfer container on transfer carriage and covers the capping of transfer container;Manipulator is connected with sample holder device.Sample can ensure that the activity of cell in profound hypothermia environment in transport process, maintain profound hypothermia state of the cell in transhipment, reduce and adversely affected caused by cell due to temperature fluctuation, simple in structure, convenient and safe, efficient.

Description

Biological sample transfer device
Technical field
The utility model is related to biological sample access technique fields, in particular to a kind of biological sample transfer device.
Background technology
The long term storage of biological sample reduces the biochemical reaction in sample usually using alap temperature, improves sample The stability of various composition in this, temperature is lower, and the holding time of sample is longer.Typically freeze-stored cell is placed in sample tube In, sample tube is placed in by sample box in storage rack, and storage rack is integrally placed in liquid nitrogen, to realize the guarantor steady in a long-term of sample It deposits.
When needing using cell, the test tube in corresponding sample box in liquid nitrogen container is moved to by freezing equipment automatically It transports in sample box, then manually takes away and transport sample box with to be used, but fetch and deliver that transhipment time is longer, and freeze-stored cell exists in this way The residence time is longer in room temperature, Cell viability can be caused to reduce.
Utility model content
The purpose of this utility model is to provide a kind of biological sample transfer devices, to solve to transport by hand under current room temperature The problem of frozen cell causes Cell viability to reduce.
To realize the utility model aim, the technical solution used for:Biological sample conveyer method, including transhipment vehicle with walking machine Structure, transfer carriage, gripping and the manipulator for shifting sample being connected in transhipment walking mechanism;Transfer container is provided on transfer carriage With the capping of capping transfer container;Manipulator is connected with sample holder device.Transfer container is targetedly needed for placing The sample to be transported of transhipment.
The low temperature stopped suitable for biological sample can be kept it in transfer container by modes such as liquid nitrogen, ensures that sample is lived Property, transhipment walking mechanism and manipulator, transfer carriage and transfer container forming apparatus are whole, move integrally and realize taking for sample It puts, low temperature transhipment, walk, realize low temperature transhipment, integrality and the degree of automation are strong, and light structure is convenient.
When needing the sample to be transported transhipment by target ground to walk, transhipment walking mechanism drives transfer container to be moved to target Sample to be transported is transferred in transfer container by ground, manipulator;Multiple targets when, i.e., with arriving each target successively, successively Be transferred in transfer container, then by transhipment walking mechanism with transfer container by need to transport targetedly to be transported Sample is transported through, and realizes the biological sample that can once transport multiple target ground.It realizes with can once transporting multiple targets Biological sample.
When needing sample to be transported with being transferred to target, transhipment walking mechanism, which drives, carries turning for sample to be transported Transport container with being moved to target, manipulator takes out the sample to be transported in transfer container with moving to target;Multiple targets when, It is to each target mobile successively with transfer container from transhipment walking mechanism, it is placed in transfer container needed for targetedly distinguishing Sample to be transported.
Further, the transhipment walking mechanism is ground running vehicle or driving.
Further, at least one transport sample box for holding sample tube is provided in the transfer container.
Further, the grip device includes sample box fixture and test tube fixture.
Further, the transfer container, which has, is provided with the box frame that sample box is transported in support, and box frame has corresponding in each fortune Enclosing outside deposit box, and correspondence is provided with the shrapnel for stretching into enclosing in one corner of transport sample box.
Further, the capping is placed in transfer container upper end;Capping upper end has the envelope being adapted to sample holder device Lid grasping structures.
Further, it is covered with outer cover jointly outside the manipulator and transfer container.
Further, the outer cover is provided with sampling gate.
The utility model has the beneficial effects that being moved to access arrangement successively with transfer container by transporting walking mechanism Or target of the sample at etc., the sample to be transported in transfer container is picked and placeed using manipulator, it is entire to transport Process does not need people's manual operations, and the sample in transhipment walking all always in transfer container, can pass through liquid nitrogen in transfer container Etc. modes keep it in the profound hypothermia stopped suitable for biological sample, ensure that sample activity, such conveyer method are able to maintain that Profound hypothermia state of the cell in transhipment, is reduced and is adversely affected caused by cell due to temperature fluctuation, simple in structure, convenient Safety, it is efficient.
Description of the drawings
Fig. 1 is the structural schematic diagram for the biological sample transfer device that the utility model embodiment provides;
Fig. 2 is the structural representation for removing top outer cover for the biological sample transfer device that the utility model embodiment provides Figure, the capping of transfer container, which is in, removes state;
Fig. 3 is the partial structural diagram without capping and lower part outer cover in Fig. 2;
Fig. 4 is the structural schematic diagram of box frame;
Fig. 5 is the sample holder apparatus structure schematic diagram that quick-changing mechanism is connected to using sample box fixture;
Fig. 6 is the structural schematic diagram of quick-changing mechanism;
Fig. 7 is the sectional view at quick-changing mechanism fixing sleeve;
Fig. 8 is the structural schematic diagram of sample box fixture;
Fig. 9 is the structural schematic diagram of test tube fixture;
Reference numeral:1- transports walking mechanism, 2- manipulators, 3- transfer carriages, 4- transfer containers, 5- transport sample box, 6- Fixed plate, 7- cappings, 8- sample tubes, 9- seal lid locating structures, 10- cover grasping structures, 11- outer covers, 12- sampling gates, 13- Box frame, 14- enclosings, 15- shrapnels, 16- sample box fixtures, 17- test tube fixtures, 18- quick-changing mechanisms, 19- connecting plates, 20- fixtures Sliding block, 21- clamp arm, 22- compressed springs, 23- inserting grooves, 24-clamping faces, 25- mounting plates, the first clamping jaws of 26-, 27- second are pressed from both sides Pawl, 28- positioning pins, 29- location holes, 30- fixing sleeves, 31- movable parts, 32- discharging springs.
Specific implementation mode
The utility model is further described in detail below through specific implementation examples and in conjunction with the accompanying drawings.
Fig. 1 to Fig. 9 shows biological sample transfer device provided by the utility model, including transhipment walking mechanism 1, connection In the manipulator 2 for transporting the transfer carriage 3 in walking mechanism 1, gripping and shifting sample;4 He of transfer container is provided on transfer carriage 3 Cover the capping 7 of transfer container 4;Manipulator 2 is connected with sample holder device.
Transfer container 4 is driven with being moved at least one target using transhipment walking mechanism 1, transfer container 4 is for placing The corresponding sample to be transported in each target ground;Using manipulator 2, corresponding sample to be transported is taken out to target from transfer container 4 is interior Ground, or the sample to be transported on target ground is put into transfer container 4.When being target multiple, then by transporting 1 band of walking mechanism Dynamic transfer container 4 with being moved to next target, then carries out above-mentioned " using manipulator 2, taken out accordingly from transfer container 4 is interior Sample to be transported with arriving target, or by the sample to be transported on target ground is put into transfer container 4 ", so repeat, it is each until completing The sample on target ground is transported.
Manipulator 2 can be mounted on transfer carriage 3 or in transhipment walking mechanism 1.Manipulator 2 is mounted on transfer carriage 3, is followed Device is integrally walked together, is walked and is carried out picking and placeing for sample by manipulator 2 to any target location.Transporting walking mechanism 1 is Ground running vehicle or driving, in ground running transhipment or the walking of suspension type transhipment.
Transfer container 4 is for placing sample to be transported.At least one sample can be held by being provided in transfer container 4 The transport sample box 5 of test tube 8, sample tube 8, which is placed into, transports in sample box 5, after manipulator 2 grips out transport sample box 5, The sample tube 8 in box is gripped again and is shifted.
When multiple transports sample box 5 being arranged in transfer container 4, during present apparatus use, optional one vacant It transports sample box 5 to use as transfer sample box, in this way while the sample transhipment for realizing disposable multiple target ground, in machine Tool hand 2 does not interfere with the stop environment temperature of other samples when shifting, the vacant transport sample box 5 as transfer sample box can For transfer, other transport sample box 5 for placing the sample to be transported for targetedly needing to transport.Transporting sample box 5 is At two, it is arranged side by side in transfer container 4.
When needing sample to be transported with being transferred to target, manipulator 2 will transport in sample box 5 and correspond to waiting for for target ground Transhipment sample is put into transfer sample box, and then transfer sample box is taken out transfer container 4 and with being put into target by manipulator 2;In waiting for Turn after the sample to be transported in sample box is removed, manipulator 2 gets back to transfer sample box in transfer container 4;
When needing the sample to be transported by target ground to be transferred out, empty transfer sample box is taken out transhipment by manipulator 2 Container 4 and with being put into target, after the sample to be transported on target ground is put into transfer sample box, manipulator 2 takes transfer sample box It returns in transfer container 4, and the sample to be transported in transfer sample box is transferred to and is transported in sample box 5.
Sample box 5 is transported in setting, and when carrying sample tube 8 by transporting sample box 5, sample holder device includes sample box Fixture 16 and test tube fixture 17.Be connected with quick-changing mechanism 18 on manipulator 2, sample box fixture 16 and test tube fixture 17 can respectively with Quick-changing mechanism 18 connects, and sample box fixture 16 and test tube fixture 17 are placed on transfer carriage 3, that is, uses " the biology applied before Sample holder counter structure in sample low-temperature extraction method and extraction system ":
Sample box fixture 16 and test tube fixture 17 include connecting plate 19, the two of the opposite sliding setting in 19 lower end of connecting plate Fixture slide block 20, two fixture slide blocks 20 are fixedly installed clamp arm 21, compressed spring 22 are connected between two clamp arm 21;Two clamp arm Inserting groove 23 is all had on 21.The relative movement of two clamp arm 21 is driven to realize transport sample box 5 or sample by stretching into inserting groove 23 The clamping of this test tube 8.The opposite face of two clamp arm 21 is clamping face 24, and the clamping face 24 of clamp arm 21 is and fortune in sample box fixture 16 5 matched plane of deposit box, in test tube fixture 17 clamping face 24 of clamp arm 21 be with 8 matched cambered surface of sample tube, and Clamp arm 21 may be configured as from top to bottom tapering into, and is clamped in two clamp arm 21 in the gap to enter adjacent sample test tube 8 Sample tube 8.Sample box fixture 16 is different from 24 shape of clamping face of clamp arm 21 in test tube fixture 17, other constructions are identical.
Quick-changing mechanism 18 includes the mounting plate 25 being connect with manipulator 2, two be fixed on 25 opposite sides of mounting plate two A clamping jaw driving element;One clamping jaw driving element connects two first clamping jaws 26, and two the first clamping jaws 26 extend to mounting plate 25 lower section drives clamping fixture(Sample box fixture 16 or test tube fixture 17)Connecting plate 19;Another clamping jaw driving element Two second clamping jaws 27 are connected, respectively with 23 Corresponding matching of inserting groove of two clamp arm 21, stretches into and drives 21 phase of clamp arm in inserting groove 23 It is clamped to mobile.Clamping jaw driving element can be clamping jaw cylinder or electronic clamping jaw etc..
Mounting plate 25 is fixedly installed positioning pin 28 straight down, and it is matched fixed with positioning pin 28 to be opened up on connecting plate 19 Position hole 29, for the positioning between the two to connect.25 lower end of mounting plate is fixed with fixing sleeve 30, and the lower end in fixing sleeve 30 has Step is provided with the movable part 31 that fixing sleeve 30 is stretched out in lower end in fixing sleeve 30, is provided between movable part 31 and connecting plate 19 Discharging spring 32.Movable part 31 has the boss for supporting and being located on step.Quick-changing mechanism 18 switches sample box fixture 16 and test tube clamp When having 17, the auxiliary under the effect of discharging spring 32 of movable part 31 compresses the connecting plate 19 of sample box fixture 16 or test tube fixture 17, It is detached to help the two.
The conventional clamp of other existing conventional clamping jaws etc. also can be used in sample holder device, realizes the gripping of sample i.e. It can.
Capping is placed in transfer container upper end.There are the capping grasping structures 10 being adapted to sample holder device in capping 7.Figure In capping grasping structures 10 be the rectangular block being adapted to sample box fixture 16, may be alternatively provided as the column being adapted to test tube fixture 17 Body etc..Realize that the keying of capping 7, operation simplify by manipulator 2 in this way, apparatus structure is simple and perfect in shape and function, occupied space It is small.Other existing cap-opening mechanisms can also be used to open capping 7.
It is covered with outer cover 11 jointly outside manipulator 2 and transfer container 4, manipulator 2 is made to be in same envelope with transfer container 4 Space is closed, outer cover 11 is provided with sampling gate 12, and the keying of sampling gate 12 can pass through the existing ways such as artificial or mechanical lifting reality It is existing.Transfer container 4 and manipulator 2 can be at same enclosure space, help the isolation of manipulator 2 in shifting sample processes as possible Vapor in air.When being sample access arrangement with transporting target, the sampling gate 12 of enclosure space is opened, and enclosure space is made It is communicated with the docking of sample access arrangement, then manipulator 2 is communicated in the space to be formed in the two docking and operated.Due to sample tube 8 can be because encountering the vapor in air due to frosting from the removal of profound hypothermia environment, and manipulator 2 and transfer container 4 are in same closing Space avoids vapor in this way after the vapor in emptying enclosure space, in the transfer operation of the gripping sample of manipulator 2 and makes At the 8 surface frosting of sample tube of low temperature, cause sample tube is opposite to become larger and be unfavorable for subsequent process, be not easy to put after frosting Set, easy stick to each other the problems such as.
Transfer container 4, which has, is provided with the box frame 13 that sample box 5 is transported in support, and box frame 13 has corresponding in each transport sample box Enclosing 14 outside 5, and correspondence is provided with the shrapnel 15 for stretching into enclosing 14 in 5 one corner of transport sample box.Enclosing 14 can be The enclosing 14 for the protrusion being separately provided can also be the groove opened up on box frame 13, and the cell wall of groove, which is formed in, transports sample box 5 Outer enclosing 14, is shown in Fig. 4.Shrapnel 15 is set at one jiao, when transport sample box 5 being made to be put on box frame 13, the elastic force of shrapnel 15 Sample box 5 will be transported to diagonally opposed abutting, and just be pushed against enclosing 14 so that transporting the adjacent both sides of sample box 5 corresponding this is right Both sides on angle.Make the effective position on box frame 13 of transport sample box 5, places reliably, consistency is high, at the same time, conveniently picks up It takes and picks and places conveniently.13 upper end of box frame can be located in 4 upper end of transfer container by fixed plate 6.
The seal lid locating structure 9 that positioning is provided after promising capping 7 is removed is set on transfer carriage 3, and seal lid locating structure 9 can be The corresponding positioning protrusion in 7 inner rings of capping, positioning protrusion are arranged on transfer carriage 3, and capping 7 can detain after removing and be placed on convex On rising, positioning is placed;Other existing positioning methods also can be used in seal lid locating structure 9, are such as arranged at 7 outer rings of corresponding capping The locating slot etc. of 7 lower edges of wall or corresponding capping.Landing slab, manipulator 2 and positioning protrusion is arranged in the top of transfer carriage 3 All it can mount on landing slab.
The above descriptions are merely preferred embodiments of the present invention, is not intended to limit the utility model, for this For the technical staff in field, there can be various modifications and variations in the spirit and principles of the utility model, these are equivalent Modification or replacement etc., are all contained within the scope of protection of the utility model.

Claims (8)

1. biological sample transfer device, which is characterized in that including transhipment walking mechanism, the transhipment being connected in transhipment walking mechanism Frame, gripping and the manipulator for shifting sample;It is provided with transfer container on transfer carriage and covers the capping of transfer container;Manipulator connects It is connected to sample holder device.
2. biological sample transfer device according to claim 1, which is characterized in that the transhipment walking mechanism is ground row Mule carriage or driving.
3. biological sample transfer device according to claim 1, which is characterized in that be provided at least in the transfer container One transport sample box for holding sample tube.
4. biological sample transfer device according to claim 3, which is characterized in that the grip device includes sample box folder Tool and test tube fixture.
5. biological sample transfer device according to claim 3, which is characterized in that the transfer container is provided with support The box frame of sample box is transported, box frame has the corresponding enclosing outside each transport sample box, and corresponds to and transporting one turn of sample box The shrapnel for stretching into enclosing is provided at angle.
6. biological sample transfer device according to claim 1, which is characterized in that the capping is placed on transfer container End;Capping upper end has the capping grasping structures being adapted to sample holder device.
7. biological sample transfer device according to claim 1, which is characterized in that outside the manipulator and transfer container It is covered with outer cover jointly.
8. biological sample transfer device according to claim 7, which is characterized in that the outer cover is provided with sampling gate.
CN201721672278.9U 2017-12-05 2017-12-05 Biological sample transfer device Active CN207658395U (en)

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Application Number Priority Date Filing Date Title
CN201721672278.9U CN207658395U (en) 2017-12-05 2017-12-05 Biological sample transfer device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201721672278.9U CN207658395U (en) 2017-12-05 2017-12-05 Biological sample transfer device

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107934226A (en) * 2017-12-05 2018-04-20 基点维科(成都)医疗机器人技术有限公司 Biological specimen conveyer method and the transfer device for realizing this method
CN111903661A (en) * 2019-05-08 2020-11-10 青岛海特生物医疗有限公司 Liquid nitrogen storage device
CN115367319A (en) * 2022-09-01 2022-11-22 上海原能细胞生物低温设备有限公司 Sample warehouse equipment for whole-course cold chain aluminum plate access

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107934226A (en) * 2017-12-05 2018-04-20 基点维科(成都)医疗机器人技术有限公司 Biological specimen conveyer method and the transfer device for realizing this method
CN111776730A (en) * 2017-12-05 2020-10-16 基点生物科技(成都)有限公司 Biological sample transfer method and transfer device for implementing same
CN111903661A (en) * 2019-05-08 2020-11-10 青岛海特生物医疗有限公司 Liquid nitrogen storage device
CN111903661B (en) * 2019-05-08 2024-02-20 青岛海特生物医疗有限公司 Liquid nitrogen storage device
CN115367319A (en) * 2022-09-01 2022-11-22 上海原能细胞生物低温设备有限公司 Sample warehouse equipment for whole-course cold chain aluminum plate access

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CP01 Change in the name or title of a patent holder

Address after: 611730 129 Shengli North Street, Deyuan town (Jingrong town), Pidu District, Chengdu City, Sichuan Province

Patentee after: Base Biotechnology (Chengdu) Co.,Ltd.

Address before: 611730 129 Shengli North Street, Deyuan town (Jingrong town), Pidu District, Chengdu City, Sichuan Province

Patentee before: JIDIAN WEIKE (CHENGDU) MEDICAL ROBOT TECHNOLOGY Co.,Ltd.

CP01 Change in the name or title of a patent holder