CN207492836U - A kind of experimental provision of intermittence low-oxygen environment - Google Patents
A kind of experimental provision of intermittence low-oxygen environment Download PDFInfo
- Publication number
- CN207492836U CN207492836U CN201720455188.8U CN201720455188U CN207492836U CN 207492836 U CN207492836 U CN 207492836U CN 201720455188 U CN201720455188 U CN 201720455188U CN 207492836 U CN207492836 U CN 207492836U
- Authority
- CN
- China
- Prior art keywords
- concentration monitor
- animal
- gas
- experimental chamber
- hole
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Landscapes
- Investigating Or Analysing Biological Materials (AREA)
- Accommodation For Nursing Or Treatment Tables (AREA)
- Respiratory Apparatuses And Protective Means (AREA)
Abstract
The utility model discloses a kind of experimental provision of intermittence low-oxygen environment, including animal experimental chamber, monitoring device and gas control equipment；Animal experimental chamber is cuboid cabin made of organic glass, and top surface picks and places hole and sealing cover equipped with animal, and bottom is equipped with soda lime and anhydrous calcium chloride, and passes through web plate and separated with top nacelle；Animal experimental chamber the first side wall is set connects air and N respectively there are two air admission hole2Intake line, animal experimental chamber second sidewall is set connects O respectively there are two gas sampling hole2Concentration monitor is popped one's head in and CO2Concentration monitor is popped one's head in, the gas pressure balancing hole that animal experimental chamber third side wall is equipped with.The utility model can more reliably ensure the gaseous environment in experimental rig, reduce the interference of other gases, the CO that particularly animal breath activity generates to the greatest extent2。
Description
Technical field
The utility model is related to a kind of toy experiment intermittent hypoxia device, specially one kind passes through gas control equipment
Regulate and control the intermittence low-oxygen experimental apparatus for small animals of air-flow.
Background technology
Existing intermittence low-oxygen animal experiment device is mainly used in the pathophysiological condition of simulation intermittence low-oxygen, is sleeping
There are similar mechanism for the research fields such as dormancy apnea syndrome, altitude acclimatization and hypoxic precondition.
The existing mechanism that interval hypoxia is simulated by the way of hypobaric chamber of current research method, also takes normal pressure low
The method of oxygen case, the former the advantages of be that degree of oxygen deficiency can be controlled accurately, but it is chiefly used in the research of high altitude anoxia, shortcoming
It is more apparent：Equipment requirement is higher, cannot accurately reflect the situation of anoxic under normal pressure, and cannot meet sleep apnea synthesis
Levy the requirement of Repeated Brief hypoxia-reoxygenation cycle.Therefore start to occur the animal of interval hypoxia under the conditions of simulated normal pressure in recent years
The characteristics of model, this model I is maximum, is to employ the mode of atmosphere intermission anoxic, closer to the pathologic, physiologic of disease
Feature.
There are some experimental rigs in the prior art, related hypoxemia zoopery demand can be met, but remained
Some defects：For example, cannot more reliably ensure the gaseous environment in experimental rig, can there are other gases to interfere, including dynamic
The CO that object respiratory activity generates2, the interference of the outer atmospheric environment of device etc..
Utility model content
The purpose of this utility model is that：It is proposed a kind of experimental provision of intermittence low-oxygen environment, it can more reliably really
The gaseous environment in experimental rig is protected, reduces the interference of other gases, the CO that particularly animal breath activity generates to the greatest extent2。
The purpose of this utility model is realized by following technical proposals：
A kind of experimental provision of intermittence low-oxygen environment, including animal experimental chamber, monitoring device and gas control equipment, prison
It surveys device and includes O2Concentration monitor and CO2Concentration monitor, gas control equipment include air compressed gas cylinder, N2Compression
Gas bomb, gas open-close valve and control device；Animal experimental chamber is cuboid cabin made of organic glass, and top surface is equipped with animal
Hole and sealing cover are picked and placeed, bottom is equipped with soda lime and anhydrous calcium chloride, and passes through web plate and separated with top nacelle；Animal is real
Hatch checking the first side wall is set connects air and N respectively there are two air admission hole2Intake line, air and N2Intake line is respectively equipped with gas
Body switch valve, and pass through control device respectively with air compressed gas cylinder, N2Compressed gas cylinder connects, animal experimental chamber the
Two side walls are set connects O respectively there are two gas sampling hole2Concentration monitor is popped one's head in and CO2Concentration monitor is popped one's head in, O2Concentration monitor is popped one's head in
And CO2Concentration monitor probe is respectively and O2Concentration monitor and CO2Concentration monitor connects, and animal experimental chamber third side wall is equipped with
Gas pressure balancing hole.
In the utility model, the animal of animal experimental chamber picks and places hole and conveniently picks and places experimental animal, and gas pressure balancing hole makes
Nacelle inside and outside air pressure balance is obtained, keeps normal pressure state, soda lime can adsorb animal breath activity in nacelle with anhydrous calcium chloride
The CO of generation2.Gas control equipment provides air and N according to preset time parameter for animal experimental chamber exchange2, realize that animal is real
The low-oxygen environment of hatch checking, O2Concentration monitor and CO2Concentration monitor monitors the gaseous environment of animal experimental chamber so that animal is real
Hatch checking has been at intermittence low-oxygen environment, and excludes the CO that animal breath activity generates as far as possible2Interference.
Alternatively, animal experimental chamber the first side wall and second sidewall are oppositely arranged.In the program, the first side wall and second
Side wall is oppositely arranged so that air and N2Input and O2And CO2Concentration monitor is relatively distant from setting so that O2And CO2Concentration monitor
It is more accurate.
As further selection, animal experimental chamber third side wall is set between the first and second side walls.In the program, third
Side wall is centrally located so that gas pressure balancing hole can realize inside and outside air pressure balance and to air and N2Input and O2
And CO2Concentration monitor brings adverse effect.
Alternatively, gas pressure balancing hole aperture 0.5mm.In the program, preferred suitable aperture is too small to ensure
Inside and outside air pressure balance, it is excessive and external environment can be caused to bring interference to gaseous environment in animal experimental chamber.
Alternatively, O2Concentration monitor, CO2Concentration monitor and gas open-close valve are connect respectively with control device, control
Device is according to O2Concentration monitor and CO2The switch of the real-time data signal control gas open-close valve of concentration monitor feedback, it is ensured that
Animal experimental chamber is in the intermittence low-oxygen environment needed for research.
The aforementioned main scheme of the utility model and its each further selection scheme can be freely combined to form multiple schemes,
The scheme that can be used and be claimed for the utility model；And the utility model, (each non conflicting selection) selection between and
It can also be freely combined between other selections.Those skilled in the art are after the present invention program is understood according to the prior art and public affairs
Know that common sense can be understood there are many combining, be the claimed technical solution of the utility model, do not do exhaustion herein.
The beneficial effects of the utility model：It can more reliably ensure the gaseous environment in experimental rig, reduce it to the greatest extent
He interferes gas, the CO that particularly animal breath activity generates2Interference.In addition, the present apparatus is easy to condition needed for regulation and control experiment, letter
Change exhaust solenoid valve and absorption unit of dioxide carbon, reduce apparatus structure complexity and production cost, and with equal work(
Can, research needs can be met, be worthy of popularization.
Description of the drawings
Fig. 1 is the structure diagram of the utility model embodiment；
In figure, 1. animal experimental chambers, 11. animals pick and place hole, 12. air admission holes, 13. gas pressure balancing holes, 14. web plates,
15. soda lime and anhydrous calcium chloride, 2.O2Concentration monitor, 3.CO2Concentration monitor, 4. air compressed gas cylinders, 5.N2Pressure
Contracting gas bomb, 6. gas open-close valves, 7. control devices, 8.O2Concentration monitor is popped one's head in, 9.CO2Concentration monitor is popped one's head in.
Specific embodiment
The utility model is further described with reference to specific embodiments and the drawings.
Refering to what is shown in Fig. 1, a kind of intermittence low-oxygen toy experimental box and control system, including animal experimental chamber 1, detection
Device and gas control equipment, detection device include O2Concentration monitor 2 and CO2Concentration monitor 3, gas control equipment includes
Air compressed gas cylinder 4, N2Compressed gas cylinder 5, gas open-close valve 6 and control device 7.Animal experimental chamber 1 is had by 4mm thickness
30*15*15cm cuboids cabin is made in machine glass, and top surface takes the hole of a diameter of 10cm to pick and place hole 11 for animal, seals, be convenient for
Animal is picked and placeed in experimentation.It is air admission hole 12 that 1 right side wall center of animal experimental chamber, which takes two, the hole of a diameter of 5mm, is connected respectively
Connect air and N2Intake line, air and N2Intake line is respectively equipped with gas open-close valve 6, and pass through control device 7 respectively with sky
Gas compressed gas cylinder 4, N2Compressed gas cylinder 5 connects.Air and N2Two gas open-close valves 6 on intake line respectively with
Control device 7 connects, and control device 7 controls the switch of gas open-close valve 6, controls air and N2Input, maintain zoopery
Intermittence low-oxygen environment in cabin 1.Further, O2Concentration monitor 2 and CO2Concentration monitor 3 and gas open-close valve 6 divide
It is not connect with control device 7, control device 7 is according to O2The O of concentration monitor 22Concentration signal and CO2The CO of concentration monitor 32
Concentration signal controls the switch of gas open-close valve 6, is controlled so as to fulfill more accurately intermittence low-oxygen environment.Control device 7 can
Realized using existing various devices, such as microcontroller, single chip circuit program are easy to rewrite, can meet different hypoxemia degree and
The demand of hypoxemia interval time；Various matched control valves, such as solenoid valve can be used in corresponding gas open-close valve 6.
It is gas sampling hole that 1 left side wall of animal experimental chamber, which takes the aperture two of a diameter of 0.5mm, connects O respectively2Concentration is supervised
Probing head 8 and CO2Concentration monitor probe 9, O28 and CO of concentration monitor probe2Concentration monitor probe 9 is respectively and O2Concentration monitor 2
And CO2Concentration monitor 3 connects.It is gas pressure balancing that 1 center side wall of animal experimental chamber, which takes the aperture one of a diameter of 0.5mm,
Hole 13, for balancing gas pressure in cabin.1 lower part of animal experimental chamber is equipped with the web plate 14 of the upper down space of isolation, 14 lower section of web plate
Animal experimental chamber bottom be equipped with soda lime and anhydrous calcium chloride 15.In experimentation, experimental animal bottom web plate in cabin
Can be freely movable on 14, CO2With the separately available soda lime and anhydrous calcium chloride for being laid on 14 times Laboratory Module bottoms of web plate of vapor
15 absorb.In order to be further reduced the CO of animal breath activity generation2It is interfered with vapor, it can also be further in zoopery
Cabin 1 sets aspirating hole, and aspirating hole connects aspiration pump, aspiration pump and CO by exhaust tube2Concentration monitor 3 respectively with control device
7 connections, control device 7 is according to CO2The CO of concentration monitor 32Concentration signal controls the switch of aspiration pump, and according to O2Concentration is supervised
Survey the O of instrument 22Concentration signal controls the switch of gas open-close valve 6, and the gas extraction of animal experimental chamber is come out, and by same step
Save air and N2Input, it is ensured that more reliable gaseous environment, and when needed thoroughly ventilation.
In addition, hypoxemia animal device design provided by the utility model, optimizes control system, together using single chip circuit
When simplify absorption unit of dioxide carbon component in exhaust outlet solenoid valve and cabin, reduce product structure complexity and production
Cost, and with equal function, research needs can be met.
The above is only the preferred embodiment of the utility model only, is not intended to limit the utility model, all at this
All any modification, equivalent and improvement made within the spirit and principle of utility model etc., should be included in the utility model
Protection domain within.
Claims (5)
1. a kind of experimental provision of intermittence low-oxygen environment, it is characterised in that：Including animal experimental chamber, monitoring device and gas control
Device processed, detection device include O2Concentration monitor and CO2Concentration monitor, gas control equipment include air compressed gas steel
Bottle, N2Compressed gas cylinder, gas open-close valve and control device；Animal experimental chamber is cuboid cabin made of organic glass, is pushed up
Face picks and places hole and sealing cover equipped with animal, and bottom is equipped with soda lime and anhydrous calcium chloride, and passes through web plate and top nacelle
It separates；Animal experimental chamber the first side wall is set connects air and N respectively there are two air admission hole2Intake line, air and N2Intake line
Be respectively equipped with gas open-close valve, and pass through control device respectively with air compressed gas cylinder, N2Compressed gas cylinder connects, and moves
Object Laboratory Module second sidewall is set connects O respectively there are two gas sampling hole2Concentration monitor is popped one's head in and CO2Concentration monitor is popped one's head in, O2It is dense
Degree monitoring probe and CO2Concentration monitor probe is respectively and O2Concentration monitor and CO2Concentration monitor connects, animal experimental chamber the
The gas pressure balancing hole that three side walls are equipped with.
2. the experimental provision of intermittence low-oxygen environment as described in claim 1, it is characterised in that：Animal experimental chamber the first side wall
It is oppositely arranged with second sidewall.
3. the experimental provision of intermittence low-oxygen environment as claimed in claim 2, it is characterised in that：Animal experimental chamber third side wall
Between the first and second side walls.
4. the experimental provision of intermittence low-oxygen environment as described in claim 1, it is characterised in that：Gas pressure balancing hole aperture
0.5mm。
5. the experimental provision of intermittence low-oxygen environment as described in claim 1, it is characterised in that：O2Concentration monitor, CO2It is dense
Degree monitor and gas open-close valve are connect respectively with control device, and control device is according to O2Concentration monitor and CO2Concentration monitor
The switch of the real time data control gas open-close valve of feedback.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201720455188.8U CN207492836U (en) | 2017-04-26 | 2017-04-26 | A kind of experimental provision of intermittence low-oxygen environment |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201720455188.8U CN207492836U (en) | 2017-04-26 | 2017-04-26 | A kind of experimental provision of intermittence low-oxygen environment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN207492836U true CN207492836U (en) | 2018-06-15 |
Family
ID=62496792
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201720455188.8U Expired - Fee Related CN207492836U (en) | 2017-04-26 | 2017-04-26 | A kind of experimental provision of intermittence low-oxygen environment |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN207492836U (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110141396A (en) * | 2019-05-24 | 2019-08-20 | 四川大学 | A kind of hypoxia device for clinical zoopery |
| CN113229156A (en) * | 2021-05-08 | 2021-08-10 | 中国人民解放军军事科学院军事医学研究院 | Animal hypoxia-sensitive individual screening device |
| CN114515612A (en) * | 2022-03-03 | 2022-05-20 | 中国人民解放军空军军医大学 | Neuroscience basic experiment operation panel |
-
2017
- 2017-04-26 CN CN201720455188.8U patent/CN207492836U/en not_active Expired - Fee Related
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110141396A (en) * | 2019-05-24 | 2019-08-20 | 四川大学 | A kind of hypoxia device for clinical zoopery |
| CN113229156A (en) * | 2021-05-08 | 2021-08-10 | 中国人民解放军军事科学院军事医学研究院 | Animal hypoxia-sensitive individual screening device |
| CN114515612A (en) * | 2022-03-03 | 2022-05-20 | 中国人民解放军空军军医大学 | Neuroscience basic experiment operation panel |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN207492836U (en) | A kind of experimental provision of intermittence low-oxygen environment | |
| CN1726061A (en) | Oxygen supply apparatus | |
| CN107773326A (en) | A kind of animal experimental chamber and its operation principle | |
| CN102907220A (en) | Circular inflation modified atmosphere grain storage device and method using device | |
| CN101889908B (en) | Gas atomization toxicant exposure box | |
| CN101241019A (en) | Robot bionic olfactory system | |
| CN105107071A (en) | Portable digital intelligent oxygen inhalation machine and control method | |
| CN209559587U (en) | A kind of gas sampling apparatus of real-time measurement Atmospheric components | |
| CN205007398U (en) | Intelligent oxygen uptake of portable digitization machine | |
| CN106442066A (en) | Soil culture device with small air collector | |
| CN110141396A (en) | A kind of hypoxia device for clinical zoopery | |
| CN104007081A (en) | Gas detection device, gas detection system and gas detection method | |
| CN103566983A (en) | Finished automobile testing room capable of testing high-and-low temperature, humidity and volatile organic compounds | |
| CN206161610U (en) | Carbon dioxide concentration detection of library device | |
| CN100455274C (en) | Normal pressure low oxygen toxicity contaminated system | |
| CN207675598U (en) | A kind of air quality surveillance device based on unmanned plane | |
| CN209203616U (en) | A kind of animal experimental chamber and its system | |
| CN206612857U (en) | A kind of multi-functional mouse inhalation anesthesia case | |
| CN207007230U (en) | A kind of environmental monitoring intelligent controlling device based on mobile technology | |
| CN205315030U (en) | Mining oxygenation control system | |
| CN204890253U (en) | Continuation ordinary pressure animal oxygen deficiency device | |
| CN207842778U (en) | A kind of refrigeration electric vehicle and the refrigerant air stoichiometry system based on liquid nitrogen | |
| CN208176752U (en) | A kind of Emergency Escape Breathing Device | |
| CN207096259U (en) | A kind of western hybridization consersion unit | |
| CN206292062U (en) | A kind of anesthesia respiratory system safety and performance detection apparatus |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20190430 Address after: 610083 No. 270 Rongdu Avenue, Jinniu District, Chengdu City, Sichuan Province Patentee after: WESTERN THEATER GENERAL HOSPITAL OF PLA Address before: 610083 Chengdu Military General Hospital, 270 Rongdu Avenue, Jinniu District, Chengdu City, Sichuan Province Patentee before: Wang Zhang |
|
| TR01 | Transfer of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20180615 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |