CN207451652U - A kind of water for injection storage distribution system for carrying superheated water sterilizing device - Google Patents
A kind of water for injection storage distribution system for carrying superheated water sterilizing device Download PDFInfo
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- CN207451652U CN207451652U CN201720308903.5U CN201720308903U CN207451652U CN 207451652 U CN207451652 U CN 207451652U CN 201720308903 U CN201720308903 U CN 201720308903U CN 207451652 U CN207451652 U CN 207451652U
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- water
- distribution system
- pipeline
- heat exchanger
- sterilizing device
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Abstract
The utility model provides a kind of water for injection storage distribution system for carrying superheated water sterilizing device, including storage tank, the water pump of storage tank is connected by outlet pipeline, use point U-shaped curved by what pipeline was connected with water pump, with the heat exchanger with the U-shaped curved connection of point, heat exchanger is connected by water return pipeline with storage tank, wherein storage tank is provided with fluid level transmitter, water pump and with point it is U-shaped it is curved between pipeline set pressure of supply water table, pipeline sets water supply sampling valve between water pump and pressure of supply water table, and flow transmitter is set in water return pipeline.Device configuration is reasonable in the utility model, has preferable sterilization effect, and selects suitable device, and the accuracy for making water for injection storage distribution system is higher.
Description
Technical field
The utility model belongs to pharmacy water for injection distribution system field more particularly to one kind carries superheated water sterilizing device
Water for injection storage distribution system.
Background technology
Microbiological indicator can increase over time in water for pharmaceutical purposes system, and microbial contamination is pharmaceutical purpose water system
Most common in system, most incident pollution.States Pharmacopoeia specifications, the microbial limit of water for injection are 10CFU/100ml, water for injection
Belong to the scope of raw water, although raw water is without according to sterile carry out management and control, necessary antibacterial means are essential；For
For the sterile pharmaceuticals water such as sterilized water for injection, States Pharmacopoeia specifications its have to comply with the requirement of sterile product.Disinfection/sterilization technology
It is that water for pharmaceutical purposes system control microbiological indicator is most conventional, most important technology, therefore, pharmacy corporation need to take suitable micro- life
Object inhibits means and periodically sterilize or sterilize, to ensure that water purification system meets with microbiological indicator in water for injection system
The bound requirements of pharmacopeia and the quality of production.
Injection water store with distribution system normal operation when Antimicrobial measure be 70 degree it is stored above or 20 degree with
Lower low-temperature storage, the pure ＆ disinfectant measures that periodically sterilize are usually steam sterilizing.Pure steam sterilizing refers to steam using high temperature, high pressure
The method that vapour sterilizes, it belongs to moist hear heat test.The penetration power of pure steam is strong, and protein, plasm colloid are in damp and hot item
Easily denaturation solidification, enzyme system are more easily damaged under part, and steam can release potential heat and carry into water is condensed into the cell
High-temperature, enhances sterilizing power, and advantage is short sterilization time, gasification latent heat, simple system；And pure steam possesses in itself without residual
The advantages that staying, be free from environmental pollution, not destroying product surface and being easy to control and reappear.Nevertheless, pure steam sterilizing is still deposited
Technically the defects of.Pure steam sterilizing needs to consider the condensed water elimination problem of minimum point, and low spot is needed to set steam trap, made
High price is expensive, complicated for operation to be also possible to introduce unnecessary danger；And if condensed water elimination is too late in pure steam sterilization process
When can cause sterilizing dead angle, it is also possible to reduce sterilization effect when being unable to reach sterilising temp.
Superheated water sterilizing is another typical moist hear heat test, and principle is the superheated water progress using high temperature, high pressure
Sterilization treatment can kill all microorganisms, stronger thin including bacterial propagule, fungi, protozoon, algae, virus and resistance
Bacterium gemma.Superheated water, which sterilizes, can cause the structure change, enzymatic inactivation and protein coagulating of cell membrane, so that cell occurs extremely
It dies.Superheated water sterilizing is widely used in pharmaceutical industry, and water for injection is stored to go out with the sterilizing of distribution system, sterilized water for injection
Superheated water sterilizing can be used in bacterium production technology and the final sterilization technique of big/small-volume injection etc..Traditional superheated water goes out
In bacterium device, the difference of device rigging position causes device sterilization effect and non-significant, and how reasonable disposition is this field to device
Researcher's focus of attention.
Utility model content
Technical problem to be solved in the utility model is to provide a kind of water for injection for carrying superheated water sterilizing device and deposits
Distribution system is stored up, device configuration is reasonable in the device, has preferable sterilization effect, and selects suitable device, makes it accurate
Degree is higher.
In order to solve the above technical problems, the technical solution adopted in the utility model：One kind is provided and carries superheated water sterilizing dress
The water for injection storage distribution system put, it is characterised in that：The water pump and water of storage tank are connected including storage tank, by outlet pipeline
Pump is connected by what pipeline connected with U-shaped curved and with the U-shaped curved connection of point heat exchanger, a heat exchanger by water return pipeline and storage tank
Connect, the storage tank is provided with fluid level transmitter, the water pump and with point it is U-shaped it is curved between pipeline be provided with pressure of supply water table, institute
It states the pipeline between water pump and pressure of supply water table and is provided with water supply sampling valve, flow transmitter is provided in the water return pipeline.
Further：The storage tank is additionally provided with respirator, rupture disk, tank body pressure gauge, temperature transmitter.
Further：The respirator is provided with respirator sterilizing temperature transmitter.
Further：Frequency converter is provided with above the water pump.
Further：It is described to use a point valve with U-shaped curved be additionally provided with of point.
Further：It is described the U-shaped curved pipeline between heat exchanger of point is provided with heat exchanger before temperature transmitter.
Further：The heat exchanger is provided with heat exchanger pressure gauge.
Further：Temperature transmitter after conductivity meter, heat exchanger, TOC inspections are also disposed in the water return pipeline
Survey instrument, pressure of return water table, return water sampling valve.
Further：The water return pipeline end is provided with spray ball, and the spray ball is located in storage tank.
Further：The fluid level transmitter is liquid level transducer of differential pressure type.
The beneficial effects of the utility model：A kind of water for injection storage distribution system for carrying superheated water sterilizing device is provided
System, fluid level transmitter are mounted on storage tank rather than on storage tank outlet pipeline.Liquid level in tank is directly measured on storage tank,
Compared on outlet pipeline, more stablize；Secondly, which is mounted on water return pipeline, monitors water return pipeline；
Furthermore the heat exchanger is mounted on water return pipeline rather than in water supply pipe, when return water temperature is not up to setting value, is then changed
Hot device is started to work, and return water is raised temperature.In addition it is also to use the heat exchanger when superheated water sterilizes, and also has and sterilize
Refrigerating function afterwards.
Description of the drawings
Fig. 1 is the structure diagram for the water for injection storage distribution system for carrying superheated water sterilizing device.
Reference numeral in figure, 1- storage tanks；2- water pumps；3- frequency converters；4- water supply sampling valves；5- pressure of supply water tables；6- points
Valve；7- points are U-shaped curved；Temperature transmitter before 8- heat exchangers；9- heat exchangers；10- heat exchanger pressure gauges；11- conductivity meters；
Temperature transmitter after 12- heat exchangers；13-TOC detectors；14- flow transmitters；15- pressure of return water tables；16- return water sampling valves；
17- sprays ball；18- respirator sterilizing temperature transmitters；19- respirators；20- rupture disks；21- tank body pressure gauges；22- temperature
Transmitter；23- pipelines；24- outlet pipelines；25- water return pipelines；26- fluid level transmitters.
Specific embodiment
With reference to the content of embodiment, more specifically elaboration the utility model.The implementation of the utility model is not limited to
The following examples, the accommodation in any form made to the utility model or changed all should be in the protection model of the utility model
In enclosing.
Embodiment 1：
A kind of water for injection storage distribution system for carrying superheated water sterilizing device, as shown in Figure 1, including storage tank 1, water pump
2nd, with U-shaped curved 7, heat exchanger 9 is put, wherein storage tank 1 connects water pump 2 by outlet pipeline 24, passes through 23 He of pipeline with point U-shaped curved 7
Water pump 2 connects, and is connected with point U-shaped curved 7 by pipeline 23 and heat exchanger 9, heat exchanger 9 is connected to storage finally by water return pipeline 25
Tank 1.Fluid level transmitter 26 is provided on storage tank 1, is liquid level transducer of differential pressure type 26 in the present embodiment, with traditional liquid level transmitter
Unlike installation site, liquid level transducer of differential pressure type 26 is mounted on storage tank 1 in the present embodiment, not the outlet pipeline of storage tank
In 24, it is advantageous that directly measuring liquid level in tank on storage tank 1, more stablize compared on outlet pipeline 24；Storage tank 1
Respirator 19, rupture disk 20, tank body pressure gauge 21, temperature transmitter 22 are additionally provided with, wherein respirator 19 is provided with respirator
Sterilizing temperature transmitter 18；The top of water pump 2 is provided with frequency converter 3, water pump 2 and pipeline 23 between putting U-shaped curved 7 is provided with confession
Water pressure table 5, the pipeline 23 between water pump 2 and pressure of supply water table 5 are provided with water supply sampling valve 4, and with putting, U-shaped curved 7 setting is useful
Point valve 6 is provided with temperature transmitter 8 before heat exchanger with the pipeline 23 between point U-shaped curved 7 and heat exchanger 9, and heat exchanger 9 is set
There is heat exchanger pressure gauge 10, heat exchanger 9 is mounted on water return pipeline 25, when return water temperature is not up to setting value, then heat exchanger 9
It starts to work, return water is raised into temperature.In addition it is also to use the heat exchanger when superheated water sterilizes, and in the present embodiment
Heat exchanger also has the refrigerating function after sterilizing, but there is no refrigerating functions for traditional design.Flow is provided in water return pipeline 25
Transmitter 14, flow transmitter 14 is arranged at 2 exit of water pump in traditional technology, installs flow transmitter 14 in the present embodiment
It is that can monitor 25 flow of water return pipeline in time in the advantage of water return pipeline 25, when 25 flow of water return pipeline is less than setting value,
By frequency converter 3 water pump is controlled to raise frequency, enlargement discharge.Conductivity meter 11 is also disposed in water return pipeline 25, is exchanged heat
Temperature transmitter 12 after device, TOC detectors 13, pressure of return water table 15, return water sampling valve 16,25 end of water return pipeline are provided with spray
Ball 17 is drenched, spray ball 17 is located in storage tank 1.
This water for injection storage distribution system for carrying superheated water sterilizing device, sterilizing flow are divided into following four mistake
Journey：
(a) the water filling stage：The water for injection of injection certain volume, is advisable with 30%~40% tank level in storage tank 1；
(b) heating period：Start the circulatory system, will be stored up using the steam jacket of 1 periphery of the heat exchanger 9 in system or storage tank
Water for injection in tank 1 is heated to 121 degree from 80 degree；
(c) sterilization phase：Water for injection maintains 30min at a temperature of 121 degree, and ensures storage tank pot temperature, pipeline temperature
Degree and respirator sterilising temp, which are both needed to reach 121 degree, starts timing；
(d) cooling stage：After sterilizing, cooling water control program is opened, Xun Huan water for injection cools down by predetermined speed
To design temperature.
Claims (10)
1. a kind of water for injection storage distribution system for carrying superheated water sterilizing device, it is characterised in that：Including storage tank (1), lead to
Cross outlet pipeline (24) connection storage tank (1) water pump (2), with water pump (2) by pipeline (23) be connected with put U-shaped curved (7), with
Heat exchanger (9), the heat exchanger (9) connected with point U-shaped curved (7) is connected by water return pipeline (25) with storage tank (1), the storage tank
(1) it is provided with fluid level transmitter (26), the water pump (2) and the pipeline (23) between point U-shaped curved (7) is provided with pressure of supply water
Table (5), the pipeline (23) between the water pump (2) and pressure of supply water table (5) are provided with water supply sampling valve (4), the return pipe
Flow transmitter (14) is provided in road (25).
2. a kind of water for injection storage distribution system for carrying superheated water sterilizing device, feature exist according to claim 1
In：The storage tank (1) is additionally provided with respirator (19), rupture disk (20), tank body pressure gauge (21), temperature transmitter (22).
3. a kind of water for injection storage distribution system for carrying superheated water sterilizing device, feature exist according to claim 2
In：The respirator (19) is provided with respirator sterilizing temperature transmitter (18).
4. a kind of water for injection storage distribution system for carrying superheated water sterilizing device, feature exist according to claim 1
In：Frequency converter (3) is provided with above the water pump (2).
5. a kind of water for injection storage distribution system for carrying superheated water sterilizing device, feature exist according to claim 1
In：It is described to be additionally provided with point U-shaped curved (7) with point valve (6).
6. a kind of water for injection storage distribution system for carrying superheated water sterilizing device, feature exist according to claim 1
In：The pipeline (23) between point U-shaped curved (7) and heat exchanger (9) is provided with temperature transmitter (8) before heat exchanger.
7. a kind of water for injection storage distribution system for carrying superheated water sterilizing device, feature exist according to claim 1
In：The heat exchanger (9) is provided with heat exchanger pressure gauge (10).
8. a kind of water for injection storage distribution system for carrying superheated water sterilizing device, feature exist according to claim 1
In：Temperature transmitter (12) after conductivity meter (11), heat exchanger, TOC detections are also disposed in the water return pipeline (25)
Instrument (13), pressure of return water table (15), return water sampling valve (16).
9. a kind of water for injection storage distribution system for carrying superheated water sterilizing device, feature exist according to claim 1
In：Water return pipeline (25) end is provided with spray ball (17), and the spray ball (17) is located in storage tank (1).
10. a kind of water for injection storage distribution system for carrying superheated water sterilizing device, feature exist according to claim 1
In：The fluid level transmitter (26) is liquid level transducer of differential pressure type.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201720308903.5U CN207451652U (en) | 2017-03-28 | 2017-03-28 | A kind of water for injection storage distribution system for carrying superheated water sterilizing device |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201720308903.5U CN207451652U (en) | 2017-03-28 | 2017-03-28 | A kind of water for injection storage distribution system for carrying superheated water sterilizing device |
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| CN207451652U true CN207451652U (en) | 2018-06-05 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109704424A (en) * | 2018-12-29 | 2019-05-03 | 楚天科技股份有限公司 | A kind of on-line checking, sterilizing water distribution system and method for supplying water |
-
2017
- 2017-03-28 CN CN201720308903.5U patent/CN207451652U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109704424A (en) * | 2018-12-29 | 2019-05-03 | 楚天科技股份有限公司 | A kind of on-line checking, sterilizing water distribution system and method for supplying water |
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Legal Events
| Date | Code | Title | Description |
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| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| PP01 | Preservation of patent right |
Effective date of registration: 20181023 Granted publication date: 20180605 |
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| PP01 | Preservation of patent right | ||
| PD01 | Discharge of preservation of patent |
Date of cancellation: 20200609 Granted publication date: 20180605 |
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| PD01 | Discharge of preservation of patent | ||
| CB03 | Change of inventor or designer information |
Inventor after: Zhang Liqin Inventor after: He Guoqiang Inventor before: Xia Tiantian |
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| CB03 | Change of inventor or designer information | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20201028 Address after: 201600 Shanghai city Songjiang District Yuyang Road No. 799 Patentee after: SHANGHAI AUSTAR PHARMACEUTICAL TECHNOLOGY EQUIPMENT Co.,Ltd. Address before: 201100 Shanghai Minhang District, Jianchuan Road 951 Building 5 1 Floor Patentee before: MLST (SHANGHAI) Co.,Ltd. |
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| TR01 | Transfer of patent right |