CN207233700U - A kind of high pressure coupled pulse generator and time of-flight mass spectrometer - Google Patents

A kind of high pressure coupled pulse generator and time of-flight mass spectrometer Download PDF

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Publication number
CN207233700U
CN207233700U CN201721206264.8U CN201721206264U CN207233700U CN 207233700 U CN207233700 U CN 207233700U CN 201721206264 U CN201721206264 U CN 201721206264U CN 207233700 U CN207233700 U CN 207233700U
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module
high pressure
current
input
resistance
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乌月恒
张贤春
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ZHUHAI MEIHUA BIO-MEDICAL TECHNOLOGY CO LTD
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ZHUHAI MEIHUA BIO-MEDICAL TECHNOLOGY CO LTD
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Abstract

A kind of high pressure coupled pulse generator and time of-flight mass spectrometer, wherein, which includes switch drive module, the first input module, the second input module, high pressure coupling module, the first output module, the second output module, filtering voltage regulation module and current limliting filter module;Switch drive module includes driving input terminal, resistance AR1, resistance R1 and triode;First input module includes first input end, multiple first current-limiting resistances and charging capacitor;High pressure coupling module includes multiple high-voltage capacitances, and one end of high pressure coupling module is first end, and the other end is second end, and first end is connected with transistor collector, and the second input module and the first output module are connected with second end;Current limliting filter module is connected with second end;Second output module includes the second output terminal and the 4th current-limiting resistance, and one end of filtering voltage regulation module is connected between adjacent 4th current-limiting resistance, other end ground connection.The circuit structure of the utility model is complicated, output waveform stabilization.

Description

A kind of high pressure coupled pulse generator and time of-flight mass spectrometer
Technical field
High-voltage pulse generator field is the utility model is related to, when especially a kind of high pressure coupled pulse generator and flight Between mass spectrograph.
Background technology
Time of-flight mass spectrometer is a kind of very important mass spectrograph, in the mass analyser using different mass-to-charge ratioes from The time difference flown in tof tube of son detects ion, has that detection range is wide, analyze speed is fast, the spy such as simple in structure Point.It is more that repulsion is carried out to the ion of ionization using high-voltage pulse generator in time of-flight mass spectrometer ion gun (such as MALDI) Or draw, it is detected subsequently into time-of-flight mass analyzer, therefore high-voltage pulse generator is in time of-flight mass spectrometer In play an important roll.
The important indicator of high-voltage pulse generator has born the amplitude of high pressure, the rise or fall time on pulse edge, arteries and veins The delay of punching, the shake of output and impulse waveform.In the prior art, relevant circuit structure is complex, the wave belt of pulse There is larger concussion hangover, it is impossible to meet the high-voltage pulse demand of time of-flight mass spectrometer ion gun well.
Utility model content
The utility model provides a kind of high pressure coupled pulse generator and time of-flight mass spectrometer, solves existing high-voltage pulse The problem of generator architecture is complicated, output waveform is unstable.
It is according to the present utility model in a first aspect, the utility model provides a kind of high pressure coupled pulse generator, including open Close drive module, the first input module, the second input module, high pressure coupling module, the first output module, the second output module, Filtering voltage regulation module and current limliting filter module;The switch drive module includes driving input terminal, resistance AR1, resistance R1 and three Pole pipe, driving input terminal are used for input pulse signal, and driving input terminal, resistance AR1 and triode grid are sequentially connected, resistance R1 Both ends connect the emitter and grid of triode, the emitter ground connection of triode respectively;First input module includes the first input End, multiple first current-limiting resistances and charging capacitor, first input end, the first current-limiting resistance and transistor collector are sequentially connected, One end of charging capacitor is connected between two neighboring first current-limiting resistance, other end ground connection;High pressure coupling module includes multiple series windings High-voltage capacitance, and one end of high pressure coupling module is first end, and the other end is second end, the first end of high pressure coupling module with Transistor collector is connected, and the second input module and the first output module are connected with second end;Current limliting filter module one end with The second end is connected, other end ground connection;Second output module includes the second output terminal and multiple 4th current-limiting resistances, and second is defeated Outlet, the 4th current-limiting resistance and second end are sequentially connected;One end of filtering voltage regulation module be connected on two neighboring 4th current-limiting resistance it Between, other end ground connection.
Preferably, first input module further includes the first diode and the second diode, the cathode of the first diode It is connected between two the first current-limiting resistances, anode is connected on the collector of triode, and the cathode of the second diode connects the collection of triode Electrode, anode ground connection.
Preferably, the current limliting filter module includes multiple 5th current-limiting resistances and inductance sequentially concatenated.
Preferably, the filtering voltage regulation module includes multiple filter capacitors in parallel.
Preferably, multiple second limits that second input module includes the second input terminal and is connected with the second input terminal Leakage resistance.
Preferably, multiple 3rd limits that first output module includes the first output terminal and is connected with the first output terminal Leakage resistance.
Preferably, the resistance AR1 is variable resistor.
Preferably, the triode is IGBT.
Second aspect according to the present utility model, the utility model provide a kind of time of-flight mass spectrometer, including above-mentioned High pressure coupled pulse generator.
In the utility model, triode keeps ending under normal conditions, the high direct voltage of first input end input, to charging electricity Capacity charge, while charge to the capacitance of high pressure coupling module.Second input terminal input direct-current high pressure, passes through the second current-limiting resistance pair The capacitance charging of high pressure coupling module.When there is trigger pulse arrival, triode ON, its collector voltage is pulled down to ground, high The capacitance electric discharge of coupling module is pressed, this quick change changes the 3rd current-limiting resistance hot end magnitude of voltage by coupling, into And the first output terminal is influenced, the voltage quick pull-down of the first output terminal.Meanwhile filtering voltage regulation module and the 4th current-limiting resistance group Into the coupling superposition of parallel filtering circuits mask pulse, second output terminal is stablized output high pressure always, make the ripple of output Shape is more stablized.And current limliting filter module further makes circuit more safe and stable.
Brief description of the drawings
Fig. 1 is a kind of structure diagram of the high pressure coupled pulse generator of embodiment of the utility model;
Fig. 2 is a kind of structure diagram of the high pressure coupled pulse generator of embodiment of the utility model.
Embodiment
The utility model is described in further detail below by embodiment combination attached drawing.
The utility model embodiment provides a kind of high pressure coupled pulse generator, as shown in Figure 1, it includes switch drive mould Block 1, the first input module 2, the second input module 3, high pressure coupling module 6, the first output module 4, the second output module 5, filter Ripple Voltage stabilizing module 8 and current limliting filter module 7.Wherein, the switch drive module 1 includes driving input terminal 11, resistance AR1, electricity R1 and triode are hindered, driving input terminal 11, resistance AR1 and triode grid are sequentially connected, and the both ends of resistance R1 connect three poles respectively The emitter and grid of pipe, the emitter ground connection of triode, driving input terminal 11 is used for input pulse signal, to control triode Conducting and cut-off.Wherein, resistance AR1 is variable resistor, can adjust the intensity of pulse signal.
First input module 2 includes first input end, multiple first current-limiting resistances and charging capacitor, first input end, One current-limiting resistance and transistor collector are sequentially connected, and one end of charging capacitor is connected between two neighboring first current-limiting resistance, separately One end is grounded.High pressure coupling module 6 includes the high-voltage capacitance of multiple series windings, as shown in FIG., includes the high-voltage electricity of three concatenations Hold C1, C2 and C3, and one end of high pressure coupling module 6 is formed as first end, the other end is formed as second end, high pressure coupling module 6 first end is connected with transistor collector, the second input module 3 and the first output module 4 then with high pressure coupling module 6 Second end is connected.
One end of current limliting filter module 7 is connected with the second end of high pressure coupling module 6, other end ground connection;Second output mould Block 5 includes the second output terminal 51 and multiple 4th current-limiting resistances, and R11, R12, R13 and R14 in figure are the 4th current-limiting resistance. Second output terminal 51, the 4th current-limiting resistance and second end are sequentially connected;One end of filtering voltage regulation module 8 is connected on the two neighboring 4th Between current-limiting resistance, other end ground connection.
Under normality, triode Q1 cut-offs, the high direct voltage of first input end input+2KV, charges charging capacitor, The collector of triode Q1 is connected to by the first current-limiting resistance, while is charged to capacitance C1.Second input terminal input+20KV's High direct voltage, charges capacitance C3.When there is trigger pulse arrival, by resistance AR1 and R1, turn on triode Q1, three poles The collector voltage of pipe is pulled down to ground, capacitance C1 electric discharges, this quick change changes the first output by capacitance C2, C3 coupling The hot end magnitude of voltage of module 4, and then influence the first output terminal, the voltage of the first output terminal are born folded by the+20KV of normality Add+2KV, realize quick pull-down.The parallel filtering circuit being made of the 4th spacing resistance and filtering voltage regulation module, shields this coupling The pulse of superposition is closed, the second output terminal 51 is stablized output+20KV high pressures always.Limiting filter circuit makes module 7 to electricity at the same time Road is further filtered, and makes circuit more safe and stable.The present embodiment is pressure-resistant 20KV, first input end input 2KV, second Under the conditions of input terminal input 20KV, trailing edge width 50 is adjustable to 200ns, and inherent delay is less than 5ns, repeatedly triggers shake and is less than 100ps。
In one embodiment, as shown in Fig. 2, first input end 21, two first current-limiting resistances R2 and R3 are sequentially concatenated. First input module 2 further includes the first diode D1 and the second diode D2, and the cathode of the first diode D1 is connected on two Between first current-limiting resistance R2 and R3, anode is connected on the collector of triode, and the cathode of the second diode D2 connects the collection of triode Electrode, anode ground connection.Two diodes form clamp diode, the charging circuit for protecting capacitance C4, C5 and resistance R3 to be formed.
In one embodiment, the current limliting filter module 7 includes multiple 5th current-limiting resistances and inductance sequentially concatenated L1.In such as figure, the 5th current-limiting resistance includes the resistance R7 and R8 of concatenation, the wherein high voltage end of resistance R7 and the second input module 3 low-voltage end connection.
In one embodiment, the filtering voltage regulation module 8 includes multiple filter capacitors in parallel, and filtering voltage regulation module 8 can have multiple, and as shown in FIG., an end of capacitance C6, C7 and C8 are connected between resistance R11 and resistance R12, and the other end then connects Ground.An end of capacitance C9 and C10 are connected between resistance R12 and R13, and the other end is then grounded.Above-mentioned parallel filtering circuit can To shield the pulse being superimposed in 6 coupling process of high pressure coupling module, make waveform stabilization.
In one embodiment, second input module 3 include the second input terminal 31 and with 31 phase of the second input terminal Multiple second current-limiting resistances even, if R4, R5 and R6 for being concatenated in figure are the second current-limiting resistance.
In one embodiment, first output module 4 include the first output terminal 41 and with 41 phase of the first output terminal Multiple 3rd current-limiting resistance R9 and R10 even.
The utility model embodiment also provides a kind of time of-flight mass spectrometer, including above-mentioned high pressure coupled pulse occurs Device.
Above content is to combine specific embodiment further detailed description of the utility model, it is impossible to is assert The specific implementation of the utility model is confined to these explanations.For the utility model person of an ordinary skill in the technical field For, without departing from the concept of the premise utility, some simple deduction or replace can also be made.

Claims (9)

  1. A kind of 1. high pressure coupled pulse generator, it is characterised in that:
    Including switch drive module, the first input module, the second input module, high pressure coupling module, the first output module, second Output module, filtering voltage regulation module and current limliting filter module;The switch drive module includes driving input terminal, resistance AR1, electricity R1 and triode are hindered, driving input terminal is used for input pulse signal, drives input terminal, resistance AR1 and triode grid sequentially phase Even, the both ends of resistance R1 connect the emitter and grid of triode, the emitter ground connection of triode respectively;First input module includes First input end, multiple first current-limiting resistances and charging capacitor, first input end, the first current-limiting resistance and transistor collector are suitable Secondary to be connected, one end of charging capacitor is connected between two neighboring first current-limiting resistance, other end ground connection;High pressure coupling module includes more The high-voltage capacitance of a series winding, and one end of high pressure coupling module is first end, the other end are second end, the of high pressure coupling module One end is connected with transistor collector, and the second input module and the first output module are connected with second end;Current limliting filter module One end is connected with the second end, other end ground connection;Second output module includes the second output terminal and multiple 4th current-limiting resistances, Second output terminal, the 4th current-limiting resistance and second end are sequentially connected;One end of filtering voltage regulation module is connected on two neighboring 4th current limliting Between resistance, other end ground connection.
  2. 2. high pressure coupled pulse generator according to claim 1, it is characterised in that:
    First input module further includes the first diode and the second diode, and the cathode of the first diode is connected on two first Between current-limiting resistance, anode is connected on the collector of triode, and the cathode of the second diode connects the collector of triode, and anode connects Ground.
  3. 3. high pressure coupled pulse generator according to claim 1, it is characterised in that:
    The current limliting filter module includes multiple 5th current-limiting resistances and inductance sequentially concatenated.
  4. 4. high pressure coupled pulse generator according to claim 1, it is characterised in that:
    The filtering voltage regulation module includes multiple filter capacitors in parallel.
  5. 5. high pressure coupled pulse generator according to claim 1, it is characterised in that:
    Second input module includes the second input terminal and multiple second current-limiting resistances being connected with the second input terminal.
  6. 6. high pressure coupled pulse generator according to claim 1, it is characterised in that:
    First output module includes the first output terminal and multiple 3rd current-limiting resistances being connected with the first output terminal.
  7. 7. high pressure coupled pulse generator according to claim 1, it is characterised in that:
    The resistance AR1 is variable resistor.
  8. 8. high pressure coupled pulse generator according to claim 1, it is characterised in that:
    The triode is IGBT.
  9. 9. a kind of time of-flight mass spectrometer, it is characterised in that including the high pressure coupled pulse described in claim 1-8 any one Generator.
CN201721206264.8U 2017-09-19 2017-09-19 A kind of high pressure coupled pulse generator and time of-flight mass spectrometer Active CN207233700U (en)

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Application Number Priority Date Filing Date Title
CN201721206264.8U CN207233700U (en) 2017-09-19 2017-09-19 A kind of high pressure coupled pulse generator and time of-flight mass spectrometer

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CN207233700U true CN207233700U (en) 2018-04-13

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107464738A (en) * 2017-09-19 2017-12-12 珠海美华医疗科技有限公司 A kind of high pressure coupled pulse generator and time of-flight mass spectrometer

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107464738A (en) * 2017-09-19 2017-12-12 珠海美华医疗科技有限公司 A kind of high pressure coupled pulse generator and time of-flight mass spectrometer
CN107464738B (en) * 2017-09-19 2023-07-07 珠海美华医疗科技有限公司 High-voltage coupling pulse generator and time-of-flight mass spectrometer

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