CN207198090U - Expiration formula diabetes monitoring systems based on the identification of ultraviolet light acetone - Google Patents

Expiration formula diabetes monitoring systems based on the identification of ultraviolet light acetone Download PDF

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Publication number
CN207198090U
CN207198090U CN201720868245.5U CN201720868245U CN207198090U CN 207198090 U CN207198090 U CN 207198090U CN 201720868245 U CN201720868245 U CN 201720868245U CN 207198090 U CN207198090 U CN 207198090U
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China
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closed gas
pid
gas production
signal
ultraviolet light
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Expired - Fee Related
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CN201720868245.5U
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Chinese (zh)
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杨建华
蒋昱晨
熊瑞婧
孙明靖
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Northwestern Polytechnical University
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Northwestern Polytechnical University
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Abstract

The utility model proposes a kind of expiration formula diabetes monitoring systems based on the identification of ultraviolet light acetone, including closed gas producing device, Signal-regulated kinase, signal acquisition module and host computer;Closed gas producing device includes closed gas production vial and PID photoion sensors;PID photoions sensor is fixed on closed gas production vial intracavity bottom by sensor fastening device;PID photoion sensor output signals are converted to electric signal, and the signal acquisition module by wire transmission to outside by being fixed on the Signal-regulated kinase of PID photoion sensors end face, and are exported by signal acquisition module to host computer.The utility model is using PID photoion sensor vacuum ultraviolet light photos from the acetone concentration in principle detection expiration, so as to noninvasive, non-destructive, the state of an illness of real-time detection diabetes patient, the interference of the humidity such as the vapor in exhaling is avoided, solves the deficiencies of minimal invasive and cross-infection of traditional blood sampling formula detection means.

Description

Expiration formula diabetes monitoring systems based on the identification of ultraviolet light acetone
Technical field
It the utility model is related to and belong to blood sugar test instrument field, be related to a kind of Novel noninvasive quick detection to diabetes System.
Background technology
The diagnostic method of diabetes mainly has four kinds:Glycosylated hemoglobin diagnosis, oral glucose tolerance test (OGTT) method, VOC comprehensive diagnos method and gene diagnosis.Existing blood sugar test technology mainly has hospital to be based in the market The Large-scale professional detection device of blood testing, and family expenses handheld blood glucose detector.Both are all invasive detection device, it is necessary to fixed Shi Zhazhen is detected, complex operation, and cost is high.
Comparatively, VOC comprehensive diagnos method has more preferable Research Prospects, noninvasive, convenient and swift.Expiratory air can regard blood as The headspace gas of liquid, dynamic reflection plasma metabolism trend, so as to be used as biological marker.Diabetes can is suffered from by detecting Content of acetone during person exhales carrys out diagnostic monitoring.
Based on VOC comprehensive diagnos methods, Chinese invention patent --- Application No. CN201610710711.7 is related to " hospital's use Blood sugar test instrument and noninvasive management system " discloses a kind of hospital blood sugar test instrument and the noninvasive management system of diabetes, Including hospital's blood sugar test instrument, high in the clouds data platform and user with blood sugar test equipment, by network by hospital's blood glucose Detecting instrument connects with intelligent terminal, establishes personal Blood sugar management archives, there is provided the management service such as early warning.Its management system and net Network system is successfully established, but the sensor of its expiration formula blood sugar test instrument uses resistor-type gas sensor, is easily done by humidity Disturb.
Chinese utility model patent --- Application No. CN200820038071.1 is related to " exhalation diabetes detection apparatus " A kind of exhalation diabetes detection apparatus is disclosed, it is by Carbon Monoxide Detection circuit, electric field reaction unit and single chip circuit structure Into, acetone decomposition is gone out carbon monoxide using constant temperature high-frequency electric field, by detect the concentration of carbon monoxide analyze exhale in Content of acetone.Acetone in the device needs secondary response to detect, and equipment is complex.
The content of the invention
To overcome the following shortcoming of traditional blood sampling formula blood sugar detecting method:
1. invasive or minimal invasive.Improperly blood-sampling method can not only bring pain to the shallow grade of acupuncture to tester, can more produce Cross-infection etc. endangers.
2. detection process is cumbersome.To obtain accurate blood sample, the blood-sugar detecting instrument under the conditions of prior art is to blood sample demand More, tester need to continue on an empty stomach before sampling, and ensure that right place detects;
3. detection device requires high.Blood sampling formula blood-sugar detecting instrument is made up of blood glucose meter, blood taking needle, test paper three parts, test paper Go bad caused by bar is expired, preservation is improper, can all produce significant impact to testing result.Secondly, test section easily by blood, The pollution of humid air, the test paper that makes moist.Furthermore when blood sample is added drop-wise in strip, the excessive very few or position of drop of blood is inaccurate all The accuracy of test value can be influenceed.To ensure accuracy of detection and avoiding infection, it is necessary to more parts of disposable blood taking needles and test paper, equipment Complex operation, consumptive material take.
4. the response speed of medical biochemical blood glucose meter is slow, measurement accuracy is low, does not reach the requirement detected immediately.
The utility model proposes a kind of expiration formula diabetes monitoring systems based on the identification of ultraviolet light acetone, the system are automatic The exhaled gas of acquisition testing person, using PID photoion sensors, using vacuum-ultraviolet light by molecular ionization into negative ions, Collected using collection and modulate circuit and be converted into current signal, using computer as control core, data acquisition, deposited Storage, calculate, all processes of analysis.User directly carries out man-machine interaction by computer port with tester, judges disease Feelings.With non-invasive and more preferable accuracy, testing result is not disturbed by humidity.
The technical solution of the utility model is:
A kind of expiration formula diabetes monitoring systems based on the identification of ultraviolet light acetone, it is characterised in that:Including closing Formula gas producing device, Signal-regulated kinase, signal acquisition module and host computer;
The closed gas producing device includes closed gas production vial and PID photoion sensors;
PID photoions sensor is fixed on closed gas production vial intracavity bottom by sensor fastening device;PID light Ion transducer output signal is converted to electric signal by being fixed on the Signal-regulated kinase of PID photoion sensors end face, and Signal acquisition module by wire transmission to outside, and exported by signal acquisition module to host computer;
The closed gas production glass bottle, which covers, is provided with inflatable mouth, and the inner connection fluorine sebific duct of inflatable mouth, fluorine sebific duct leads to Enter closed gas production vial bottom.
Further preferred scheme, a kind of expiration formula diabetes monitoring systems based on the identification of ultraviolet light acetone, its It is characterised by:The closed gas production vial bottleneck uses frosted mouth, realizes that sealing coordinates with bottle cap.
Further preferred scheme, a kind of expiration formula diabetes monitoring systems based on the identification of ultraviolet light acetone, its It is characterised by:Disposable blow gun is housed on the inflatable mouth.
Further preferred scheme, a kind of expiration formula diabetes monitoring systems based on the identification of ultraviolet light acetone, its It is characterised by:The grass tube that the wire is covered by closed gas production glass bottle is drawn, and grass tube uses with wire Glass cement seals.
Beneficial effect
The utility model detects the acetone concentration in exhaling using PID photoion sensor vacuum ultraviolet light photos from principle, So as to noninvasive, non-destructive, the state of an illness of real-time detection diabetes patient, avoid the humidity such as the vapor in exhaling and disturb, solve The deficiencies of minimal invasive of traditional blood sampling formula detection means and cross-infection.Test response speed and measurement accuracy are improved, is reduced The cost and measurement request of system equipment, be easy to carry measurement.
Additional aspect and advantage of the present utility model will be set forth in part in the description, partly by from following description In become obvious, or by it is of the present utility model practice recognize.
Brief description of the drawings
Of the present utility model above-mentioned and/or additional aspect and advantage will in the description from combination accompanying drawings below to embodiment Become obvious and be readily appreciated that, wherein:
Fig. 1 is the schematic diagram of closed gas producing device described in the utility model.
Fig. 2 is PID sensor schematic diagram described in the utility model.
Fig. 3 is the matched curve figure of PID sensor output voltage-actual concentrations.
Fig. 4 is that the principle of the expiration formula diabetes monitoring systems described in the utility model based on the identification of ultraviolet light acetone is shown It is intended to.
Wherein:1st, inflatable mouth;2nd, PID sensor;3rd, sensor fastening device;4th, wire;5th, air storing cavity.
Embodiment
Embodiment of the present utility model is described below in detail, the example of the embodiment is shown in the drawings, wherein from beginning Same or similar element is represented to same or similar label eventually or there is the element of same or like function.Below by ginseng The embodiment for examining accompanying drawing description is exemplary, it is intended to for explaining the utility model, and it is not intended that to the utility model Limitation.
As shown in figure 1, the utility model proposes based on ultraviolet light acetone identification expiration formula diabetes monitoring systems bag Closed gas producing device, Signal-regulated kinase, signal acquisition module and host computer are included, it is not to humidity sensitive that it, which detects core, Ultraviolet photoion PID sensor, pass through other supporting devices, one complete breath acetone detection.
The closed gas producing device includes closed gas production vial and PID photoion sensors.
PID photoion sensors are a kind of high sensitivity, non-damaged data sensor applied widely.It is used for examining The carbon containing organic compound of volatility is surveyed, detectable 10ppb (parts billion) arrives 10000ppm (parts per Million) up to more than 30 kind VOC and other toxic gases.PID photoions sensor using molecule it is vacuum ultraviolet ionized this One photochemical reaction, organic molecule are energized into upper state after being absorbed to the ultraviolet light of high-energy, and being ionized into can be examined by detector The negative ions measured.After detector captures the positive and negative charge of ionized gas, it is translated into current signal and amplifies aobvious " PPM " concentration value is shown, realizes the measurement of gas concentration.And after gas ion is detected on electrode, electronics can be combined quickly, Original gas and steam molecule are reformulated, further can still be tested.Due to its high accuracy and non-destructive, PID mesh Before be in the world detect high-carbon organic matter main method.
The PID sensor that the present invention uses is the PID-TECH 2000 of Baseline companies of U.S. production, and measurement range reaches To 0-10000ppm, humidity range can reach 0-90%RH.Except high accuracy, the sensor utilizes vacuum ultraviolet ionized point Son, there is good moisture-resistant degree interference performance.The small volume of sensor, a diameter of 2cm, it is highly 1.7cm, substantially reduces whole The volume and weight of diabetes detector.It is easy to carry, measures at any time.
When encountering this kind of organic solvent of acetone in view of transparent plastic, organic solvent can be with the surface generationization of transparent plastic Learn reaction and generate the surface that other opaque materials are adhered to transparent plastic, the accuracy of detection of gas is influenceed, so this reality Vial is used with new closed gas production bottle.The closed gas production vial bottleneck uses frosted mouth, is realized with bottle cap Sealing coordinates, to ensure the sealing of device.The closed gas production glass bottle, which covers, is provided with inflatable mouth, and inflatable mouth is inner Fluorine sebific duct is connected, fluorine sebific duct is passed through closed gas production vial bottom, fully to be reacted with PID sensor, reduces loss, with Ensure measurement accuracy.Disposable blow gun is housed on the inflatable mouth, avoids cross-infection, while reduce use cost.
PID photoions sensor is fixed on closed gas production vial intracavity bottom by sensor fastening device;PID light Ion transducer output signal is converted to telecommunications by being fixed on the circular signal conditioning module of PID photoion sensors end face Number, and the signal acquisition module by wire transmission to outside, and exported by signal acquisition module to host computer.The wire leads to Cross the grass tube that closed gas production glass bottle covers to draw, grass tube is sealed with wire using glass cement.
The principle for the expiration formula diabetes monitoring systems that the utility model is identified based on ultraviolet light acetone is:Closed gas production Bottle connection expiration thief hatch, acetone concentration during the PID photoions sensor detection in test chamber is exhaled, Signal-regulated kinase will pass Sensor signal is converted to voltage signal, the voltage signal of signal acquisition module collection sensor conversion, data transmission interface and letter The connection of number acquisition process unit, sends data to outside host computer, host computer application software realizes sensor signal and acetone The corresponding of concentration calculates analysis, provides user blood glucose concentration value, detection is finally shown on the human-computer interaction interface of application software As a result.
Before use, the standard acetone gas of corresponding relation between under test gas and sensor response signal via various concentrations Calibrated.Wherein acetone gas is obtained, then imported by glass syringe and fluorine sebific duct by glass syringe by Head-space sampling Reaction unit.Nitrogen plays a part of cleaning reaction unit and transports acetone gas, led by fluorine sebific duct and vavuum pump as carrier gas Enter reaction unit.
Although embodiment of the present utility model has been shown and described above, it is to be understood that above-described embodiment is Exemplary, it is impossible to it is interpreted as not departing from the utility model to limitation of the present utility model, one of ordinary skill in the art Principle and objective in the case of above-described embodiment can be changed in the scope of the utility model, change, replace and Modification.

Claims (4)

  1. A kind of 1. expiration formula diabetes monitoring systems based on the identification of ultraviolet light acetone, it is characterised in that:Including closed gas production Device, Signal-regulated kinase, signal acquisition module and host computer;
    The closed gas producing device includes closed gas production vial and PID photoion sensors;
    PID photoions sensor is fixed on closed gas production vial intracavity bottom by sensor fastening device;PID photoions Sensor output signal is converted to electric signal by being fixed on the Signal-regulated kinase of PID photoion sensors end face, and passes through Wire transmission is exported to host computer to outside signal acquisition module by signal acquisition module;
    The closed gas production glass bottle, which covers, is provided with inflatable mouth, and the inner connection fluorine sebific duct of inflatable mouth, fluorine sebific duct is passed through envelope Enclosed gas production vial bottom.
  2. 2. a kind of expiration formula diabetes monitoring systems based on the identification of ultraviolet light acetone, its feature exist according to claim 1 In:The closed gas production vial bottleneck uses frosted mouth, realizes that sealing coordinates with bottle cap.
  3. 3. a kind of expiration formula diabetes monitoring systems based on the identification of ultraviolet light acetone, its feature exist according to claim 1 In:Disposable blow gun is housed on the inflatable mouth.
  4. 4. a kind of expiration formula diabetes monitoring systems based on the identification of ultraviolet light acetone, its feature exist according to claim 1 In:The grass tube that the wire is covered by closed gas production glass bottle is drawn, and grass tube uses glass cement with wire Sealing.
CN201720868245.5U 2017-07-18 2017-07-18 Expiration formula diabetes monitoring systems based on the identification of ultraviolet light acetone Expired - Fee Related CN207198090U (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109900776A (en) * 2017-12-11 2019-06-18 中国科学院大连化学物理研究所 The device of HCN and application in a kind of highly sensitive on-line checking expiratory air
CN110398533A (en) * 2019-07-22 2019-11-01 深圳市宝安区中心医院 A kind of skin treatment or preparation methodologies before and after low-carbon diet intervention based on acetone identification
CN111487310A (en) * 2020-04-01 2020-08-04 西安交通大学医学院第二附属医院 Diabetes detection device
CN114487190A (en) * 2022-01-25 2022-05-13 南京信息工程大学 Medical human body exhaled VOC gas detection device based on optical PID sensor

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109900776A (en) * 2017-12-11 2019-06-18 中国科学院大连化学物理研究所 The device of HCN and application in a kind of highly sensitive on-line checking expiratory air
CN110398533A (en) * 2019-07-22 2019-11-01 深圳市宝安区中心医院 A kind of skin treatment or preparation methodologies before and after low-carbon diet intervention based on acetone identification
CN111487310A (en) * 2020-04-01 2020-08-04 西安交通大学医学院第二附属医院 Diabetes detection device
CN114487190A (en) * 2022-01-25 2022-05-13 南京信息工程大学 Medical human body exhaled VOC gas detection device based on optical PID sensor
CN114487190B (en) * 2022-01-25 2023-10-03 南京信息工程大学 Medical human body exhale VOC gas detection device based on light PID sensor

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Granted publication date: 20180406

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