CN207187752U - A kind of system for preparing 6 methine 17a hydroxyl progesterone acetates - Google Patents
A kind of system for preparing 6 methine 17a hydroxyl progesterone acetates Download PDFInfo
- Publication number
- CN207187752U CN207187752U CN201721185059.8U CN201721185059U CN207187752U CN 207187752 U CN207187752 U CN 207187752U CN 201721185059 U CN201721185059 U CN 201721185059U CN 207187752 U CN207187752 U CN 207187752U
- Authority
- CN
- China
- Prior art keywords
- outer barrel
- inner cylinder
- rotating shaft
- methine
- preparing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
It the utility model is related to the production technical field of 6 methine 17a progesterone acetates,Especially a kind of system for preparing 6 methine 17a hydroxyl progesterone acetates,Including outer barrel,The top of the outer barrel offers feeding port,The bottom of the outer barrel is provided with funnel-form discharging opening,The two bottom sides of the outer barrel are mounted on supporting leg,Inner cylinder is installed in the outer barrel,It is equidistant on the water inlet pipe in the inner cylinder to offer osculum,The top of the inner cylinder offers charging aperture on the downside of feeding port,Plc controllers are installed on the supporting leg of the second rotating shaft side,The output end of the plc controllers passes through the wire input with humidity sensor respectively,The input connection of motor,The utility model is simple in construction,It is easy to use,Can quickly it be dried after raw material hydrolysis,Ensure the purity of progesterone acetate,Improve production efficiency,Reduce production cost.
Description
Technical field
It the utility model is related to the production technical field of 6- methine -17a- progesterone acetates, more particularly to a kind of system
The system of standby 6- methine -17a- hydroxyl progesterone acetates.
Background technology
6- methine -17a- hydroxyl progesterone acetates, also known as megestrol acetate, chemical formula C24H32O4, molecular weight
It is odorless tasteless for white or slightly yellow crystalline powder for 384.51,214-216 DEG C of fusing point, be dissolved in acetone, be slightly soluble in ethanol,
Ether, it is not soluble in water.Be commonly used for biochemical reagents to synthesize the intermediate of medroxyproges-terone acetate, biochemical test research, tumer it is pregnant
Ketone is semi-synthetic progestin derivative, there is certain inhibitory action to hormone-dependent neoplasm.Its mechanism of action is identical with medroxyprogesterone acetate,
The influence to pituitary gonadotropic hormone secretion is may be by, the development and growth of ovary follicle are controlled, so as to reduce estrogen
Generation.ERs is acted on, prevents it from synthesizing and re-use, disturbs the combination of itself and estrogen, suppress oncocyte
Growth.In addition, can also antagonism glucocorticoid receptor, the interference steroid hormone receptor regulation egg related to cell growth differentiation
Interaction between white.
At present, the production equipment of 17 Alpha-hydroxy progesterone acetates uses first acylation reaction, and the mode hydrolyzed afterwards is carried out, but
After existing hydrolysis device hydrolysis, the purity of product is not high, and low production efficiency, causes production cost to rise.
Utility model content
The purpose of this utility model is to solve to exist in the prior art the shortcomings of low production efficiency, cost is high, and is carried
A kind of system for preparing 6- methine -17a- hydroxyl progesterone acetates gone out.
To achieve these goals, the utility model employs following technical scheme：
Design a kind of system for preparing 6- methine -17a- hydroxyl progesterone acetates, including outer barrel, the outer barrel it is upper
Portion offers feeding port, and the bottom of the outer barrel is provided with funnel-form discharging opening, and the two bottom sides of the outer barrel are mounted on propping up
Support leg, inner cylinder is installed in the outer barrel, gap is provided between the inner cylinder and outer barrel, the both ends of the outer barrel are installed respectively
There are clutch shaft bearing and second bearing, the both ends of the inner cylinder are separately installed with first rotating shaft and the second rotating shaft, the first rotating shaft
It is connected with clutch shaft bearing, and the one end of first rotating shaft away from inner cylinder by bindiny mechanism and is arranged on supporting leg through clutch shaft bearing
The output axis connection of upper motor, second rotating shaft are connected with second bearing, and water inlet pipe is rotatably connected in second rotating shaft,
One end of the water inlet pipe is fixed on the inwall of inner cylinder by contiguous block, equidistant on the water inlet pipe in the inner cylinder to open
Provided with osculum, and humidity sensor is installed in the middle part of water inlet pipe；
The top of the inner cylinder offers charging aperture on the downside of feeding port, and charging is slidably fitted with the charging aperture
Baffle plate, equidistant in the side wall of the inner cylinder to offer spilled water hole, the spilled water hole is used cooperatively with gap, close to described second
Plc controllers are installed on the supporting leg of rotating shaft side, the output ends of the plc controllers by wire respectively with humidity sensor
The input connection of the input, motor of device.
Preferably, the bindiny mechanism includes the first belt pulley being arranged in first rotating shaft and installed in motor output shaft
On the second belt pulley, first belt pulley is connected by belt with the second belt pulley.
Preferably, the both sides of the charging aperture offer chute, and the both sides of the charging baffle plate are connected with slide.
Preferably, the motor is buncher.
Preferably, the discharging opening is movably installed with discharge baffle.
The utility model proposes a kind of system for preparing 6- methine -17a- hydroxyl progesterone acetates, beneficial effect
It is：By installing clutch shaft bearing and second bearing at the both ends of outer barrel, first rotating shaft and second turn are installed at the both ends of inner cylinder
Axle, first rotating shaft, the second rotating shaft are connected with clutch shaft bearing, second bearing respectively, ensure that inner cylinder can freely turn in outer barrel
It is dynamic, convenient use, by being rotatablely installed water inlet pipe in the second rotating shaft, and osculum is opened up on water inlet pipe, be easy to raw material
Interior liquid water is taken off, and improves production efficiency, and the utility model is simple in construction, easy to use, can quickly be dried after raw material hydrolysis,
Ensure the purity of progesterone acetate, improve production efficiency, reduce production cost.
Brief description of the drawings
Fig. 1 be the utility model proposes a kind of system for preparing 6- methine -17a- hydroxyl progesterone acetates knot
Structure schematic diagram；
Fig. 2 is Fig. 1 A portions structural representation；
Fig. 3 be the utility model proposes a kind of system for preparing 6- methine -17a- hydroxyl progesterone acetates work
Make schematic diagram.
In figure：Belt 1, first rotating shaft 2, clutch shaft bearing 3, outer barrel 4, inner cylinder 5, gap 6, spilled water hole 7, second bearing 8,
Two rotating shafts 9, plc controllers 10, water inlet pipe 11, humidity sensor 12, osculum 13, charging baffle plate 14, charging aperture 15, supporting leg
16th, motor 17, discharge baffle 18, discharging opening 19, chute 20.
Embodiment
Below in conjunction with the accompanying drawing in the utility model embodiment, the technical scheme in the embodiment of the utility model is carried out
Clearly and completely describing, it is clear that described embodiment is only the utility model part of the embodiment, rather than whole
Embodiment.
Reference picture 1-3, a kind of system for preparing 6- methine -17a- hydroxyl progesterone acetates, including outer barrel 4, outer barrel 4
Top offer feeding port, the bottom of outer barrel 4 is provided with funnel-form discharging opening 19, and discharging opening 19 is movably installed with discharge baffle
18, the two bottom sides of outer barrel 4 are mounted on supporting leg 16, and inner cylinder 5 is provided with outer barrel 4, is provided between inner cylinder 5 and outer barrel 4
Gap 6, the both ends of outer barrel 4 are separately installed with clutch shaft bearing 3 and second bearing 8, and the both ends of inner cylinder 5 are separately installed with first rotating shaft
2 and second rotating shaft 9, first rotating shaft 2 is connected with clutch shaft bearing 3, and clutch shaft bearing 3 is run through in the one end of first rotating shaft 2 away from inner cylinder 5
By bindiny mechanism and the output axis connection for being arranged on motor 17 on supporting leg 16, motor 17 is buncher, convenient use, is connected
Connection mechanism includes the first belt pulley being arranged in first rotating shaft 2 and the second belt pulley on the output shaft of motor 17, the
One belt pulley is connected by belt 1 with the second belt pulley, is easy to the rotating speed of controlled motor, facilitates the rotating speed of controlled motor 17, just
In use, production cost is saved.
Second rotating shaft 9 is connected with second bearing 8, and water inlet pipe 11, one end of water inlet pipe 11 are rotatably connected in the second rotating shaft 9
It is fixed on by contiguous block on the inwall of inner cylinder 5, it is equidistant on the water inlet pipe 11 in the inner cylinder 5 to offer osculum 13, and
The middle part of water inlet pipe 11 is provided with humidity sensor 12, and the one end of water inlet pipe 11 away from inner cylinder 5 is with being arranged on outside the device
Water pump is connected, and the input of water pump is connected by wire with the output end of plc controllers 10, and it is convenient to supply water, and is easy to hydrolysis material
The solution of interior absorption, improve production efficiency.
The top of inner cylinder 5 offers charging aperture 15 on the downside of feeding port, and charging gear is slidably fitted with charging aperture 15
Plate 14, the both sides of charging aperture 15 offer chute 20, and the both sides of charging baffle plate 14 are slidably connected with chute 20.It is convenient open or
Person's closure of feed mouth 15, equidistant in the side wall of inner cylinder 5 to offer spilled water hole 7, spilled water hole 7 is used cooperatively with gap 6, close to the
Plc controllers 10 are installed on the supporting leg 16 of the side of two rotating shaft 9, the output ends of plc controllers 10 by wire respectively with it is wet
The input connection of the input, motor 17 of sensor 12 is spent, is easy to control, it is simple to operate, it is possible to increase production efficiency.
Workflow：The utility model makes inner cylinder 5 in use, slowly run by the controlled motor 17 of plc controllers 10
Charging aperture 15 aligns with the feeding port of outer barrel 4, then pulls charging baffle plate 14, opens charging aperture 15, by raw material from charging aperture 15
Inner cylinder 5 is put into, then closure of feed baffle plate 14, motor 17 and water pump is then started by plc controllers 10 simultaneously, and pass through
Motor 17 is adjusted to middling speed state by plc controllers 10, while water pump passes through water inlet pipe by the water filling into inner cylinder 5 of water inlet pipe 11
Raw material is hydrolyzed osculum 13 on 11, and the water after hydrolysis is discharged into gap 6 by the spilled water hole 7 on inner cylinder 5, Ran Houtong
The row of discharging opening 19 is crossed, after the completion of hydrolysis, is switched off the pump using plc controllers 10, while humidity is started by plc controllers 10
Sensor 12, motor 17 is then adjusted to by fast state by plc controllers 10, rotated as inner cylinder 5 is high, under centrifugal action
Moisture content in raw material after hydrolysis is dried, humidity sensor 12 sends signal, plc controls to plc controllers 10 after the completion of drying
Device 10 processed closes motor 17, takes out progesterone acetate, can effectively improve operating efficiency.
It is described above, the only preferable embodiment of the utility model, but the scope of protection of the utility model is not
This is confined to, any one skilled in the art is in the technical scope that the utility model discloses, according to this practicality
New technical scheme and its utility model design are subject to equivalent substitution or change, should all cover in protection model of the present utility model
Within enclosing.
Claims (5)
1. a kind of system for preparing 6- methine -17a- hydroxyl progesterone acetates, including outer barrel (4), the outer barrel (4) it is upper
Portion offers feeding port, and the bottom of the outer barrel (4) is provided with funnel-form discharging opening (19), the two bottom sides of the outer barrel (4)
It is mounted on supporting leg (16), it is characterised in that：Inner cylinder (5), the inner cylinder (5) and outer barrel (4) are installed in the outer barrel (4)
Between be provided with gap (6), the both ends of the outer barrel (4) are separately installed with clutch shaft bearing (3) and second bearing (8), it is described in
The both ends of cylinder (5) are separately installed with first rotating shaft (2) and the second rotating shaft (9), and the first rotating shaft (2) connects with clutch shaft bearing (3)
Connect, and the one end of first rotating shaft (2) away from inner cylinder (5) by bindiny mechanism and is arranged on supporting leg through clutch shaft bearing (3)
(16) the output axis connection of motor (17) on, second rotating shaft (9) are connected with second bearing (8), in second rotating shaft (9)
Water inlet pipe (11) is rotatably connected to, one end of the water inlet pipe (11) is fixed on by contiguous block on the inwall of inner cylinder (5), close
It is equidistant on water inlet pipe (11) in the inner cylinder (5) to offer osculum (13), and be provided with the middle part of water inlet pipe (11) wet
Spend sensor (12)；
The top of the inner cylinder (5) offers charging aperture (15) on the downside of feeding port, and peace is slided at charging aperture (15) place
It is equidistant in the side wall of the inner cylinder (5) to offer spilled water hole (7), the spilled water hole (7) and gap equipped with charging baffle plate (14)
(6) it is used cooperatively, plc controllers (10), the plc is installed on the supporting leg (16) of the second rotating shaft (9) side
The output end of controller (10) by wire respectively the input with humidity sensor (12), motor (17) input be connected.
2. a kind of system for preparing 6- methine -17a- hydroxyl progesterone acetates according to claim 1, its feature exist
In：The bindiny mechanism includes the first belt pulley being arranged in first rotating shaft (2) and on motor (17) output shaft
Second belt pulley, first belt pulley are connected by belt (1) with the second belt pulley.
3. a kind of system for preparing 6- methine -17a- hydroxyl progesterone acetates according to claim 1, its feature exist
In：The both sides of the charging aperture (15) offer chute (20), and both sides and the chute (20) of the charging baffle plate (14) slide
Connection.
4. a kind of system for preparing 6- methine -17a- hydroxyl progesterone acetates according to claim 1, its feature exist
In：The motor (17) is buncher.
5. a kind of system for preparing 6- methine -17a- hydroxyl progesterone acetates according to claim 1, its feature exist
In：The discharging opening (19) is movably installed with discharge baffle (18).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201721185059.8U CN207187752U (en) | 2017-09-15 | 2017-09-15 | A kind of system for preparing 6 methine 17a hydroxyl progesterone acetates |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201721185059.8U CN207187752U (en) | 2017-09-15 | 2017-09-15 | A kind of system for preparing 6 methine 17a hydroxyl progesterone acetates |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN207187752U true CN207187752U (en) | 2018-04-06 |
Family
ID=61789301
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201721185059.8U Expired - Fee Related CN207187752U (en) | 2017-09-15 | 2017-09-15 | A kind of system for preparing 6 methine 17a hydroxyl progesterone acetates |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN207187752U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115818038A (en) * | 2022-12-12 | 2023-03-21 | 山东鑫浩冠新材料科技有限公司 | Raw material transportation equipment is used in lyocell fibre production |
-
2017
- 2017-09-15 CN CN201721185059.8U patent/CN207187752U/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115818038A (en) * | 2022-12-12 | 2023-03-21 | 山东鑫浩冠新材料科技有限公司 | Raw material transportation equipment is used in lyocell fibre production |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN204583007U (en) | Many components material automatic Weighing and online mixture induction system | |
| CN107494807A (en) | A kind of Drum-type fermentation device | |
| CN208860087U (en) | A kind of feed drying device that inlet amount is controllable | |
| CN206011458U (en) | A kind of preparation facilitiess of pulverized fuel ash cement slurry | |
| CN207187752U (en) | A kind of system for preparing 6 methine 17a hydroxyl progesterone acetates | |
| CN103506249B (en) | A kind of junction box glue-pouring machine | |
| CN205392264U (en) | Intelligence agitator | |
| CN104307426A (en) | Blender mixer feeding in proportion | |
| CN205379835U (en) | A agitating unit for preparing nano -material | |
| CN107226354A (en) | Weigh charging equipment and its application method of a kind of technique of saltouing | |
| CN103111209A (en) | Automatic powder material feeding method and device | |
| CN204583020U (en) | Heat-conducting oil heating mixer | |
| CN109516860B (en) | A preparation equipment for ecological compound fertilizer | |
| CN204973771U (en) | Compound fertilizer dispensing equipment | |
| CN206778433U (en) | A kind of reactor for being used to prepare powder | |
| CN207011665U (en) | A kind of quality-adjusting device of zero head waste material | |
| CN202224099U (en) | High-speed mixer capable of adjusting temperature | |
| CN202428556U (en) | Colorized ultrafine powder uniform mixing production line | |
| CN206046008U (en) | A kind of industrial starch reaction unit | |
| CN210700075U (en) | Feeding proportion controllable polyurethane structural adhesive reaction kettle | |
| CN207193163U (en) | A kind of production system of refined diene alcohol ketone acetic ester | |
| CN206384592U (en) | A kind of purified cotton is weighed transmitting device | |
| CN207415819U (en) | A kind of heat drying all-in-one machine of mutual inductor casting equipment | |
| CN106052817A (en) | Efficient material metering device | |
| CN208296513U (en) | A kind of tea seed drying box |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20180406 Termination date: 20180915 |