CN207020320U - A kind of gain correcting device of scintillation detector - Google Patents

A kind of gain correcting device of scintillation detector Download PDF

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CN207020320U
CN207020320U CN201720906974.5U CN201720906974U CN207020320U CN 207020320 U CN207020320 U CN 207020320U CN 201720906974 U CN201720906974 U CN 201720906974U CN 207020320 U CN207020320 U CN 207020320U
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gain
scintillation detector
voltage
scintillation
chip microcomputer
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姜浩
邢明俊
朱玉珍
谢庆国
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Huazhong University of Science and Technology
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Abstract

本实用新型提供一种闪烁探测器的增益校正装置,该装置包括校准射源和至少两路比较器、计数模块、温度传感器和单片微型计算机,每一路比较器均与光电器件通信连接以将不同能量段的模拟电压信号转换为数字脉冲信号;计数模块分别与每一路比较器通信连接并同时测量数字脉冲信号的计数率;温度传感器实测闪烁探测器表面温度数据;单片微型计算机与计数模块通信连接并根据计数率和实测温度数据计算目标增益以及校正电压;高压电源与单片微型计算机连接以接收校正电压,高压电源还与光电器件连接以根据校正电压实现光电器件的增益校正。本实用新型可根据温度直接调整增益,可避免信息缺失,加快了校准速度,提高了增益校正的效率。

The utility model provides a gain correction device for a scintillation detector. The device includes a calibration radiation source and at least two comparators, a counting module, a temperature sensor and a single-chip microcomputer. Each comparator is connected with a photoelectric device for communication. The analog voltage signals of different energy segments are converted into digital pulse signals; the counting module communicates with each comparator and simultaneously measures the counting rate of the digital pulse signal; the temperature sensor measures the surface temperature data of the scintillation detector; the single-chip microcomputer and the counting module The communication is connected and the target gain and correction voltage are calculated according to the counting rate and the measured temperature data; the high-voltage power supply is connected to the single-chip microcomputer to receive the correction voltage, and the high-voltage power supply is also connected to the photoelectric device to realize the gain correction of the photoelectric device according to the correction voltage. The utility model can directly adjust the gain according to the temperature, can avoid information loss, speed up the calibration speed, and improve the efficiency of gain correction.

Description

一种闪烁探测器的增益校正装置A Gain Correction Device for Scintillation Detector

技术领域technical field

本实用新型涉及核医学成像领域以及电离辐射测量领域中的一种信号校正装置和方法,更具体地涉及一种闪烁探测器的增益校正装置。The utility model relates to a signal correction device and method in the field of nuclear medical imaging and ionizing radiation measurement, more particularly to a gain correction device of a scintillation detector.

背景技术Background technique

闪烁探测器广泛应用于核医学成像和电离辐射测量领域,是实现成像或辐射测量的核心器件。闪烁探测器包括相互耦合的闪烁晶体和光电器件,闪烁晶体用以将电离辐射射线(包括X射线、伽马光子、中子、α光子和β光子等)转换为光信号,光电器件用以将该光信号转换为电信号,通过相应的电子学设计处理该电信号后可以获取到对应的到达时间、到达位置以及伽马光子的能量等信息。目前常用的闪烁晶体包括碘化钠(NaI)晶体、硅酸钇镥(LYSO)晶体、硅酸镥(LSO)晶体、硅酸钇(YSO)晶体和碘化铯(CsI)晶体等,常用的光电器件有光电二极管(APD),光电倍增管(PMT)以及新兴的硅光电倍增器(SiPM)等。Scintillation detectors are widely used in the fields of nuclear medical imaging and ionizing radiation measurement, and are the core devices for imaging or radiation measurement. The scintillation detector includes mutually coupled scintillation crystals and photoelectric devices. The scintillation crystals are used to convert ionizing radiation rays (including X-rays, gamma photons, neutrons, alpha photons and beta photons, etc.) The optical signal is converted into an electrical signal, and after the electrical signal is processed by the corresponding electronic design, information such as the corresponding arrival time, arrival position, and energy of the gamma photons can be obtained. Currently commonly used scintillation crystals include sodium iodide (NaI) crystals, yttrium lutetium silicate (LYSO) crystals, lutetium silicate (LSO) crystals, yttrium silicate (YSO) crystals, and cesium iodide (CsI) crystals. Optoelectronic devices include photodiodes (APDs), photomultiplier tubes (PMTs) and emerging silicon photomultipliers (SiPMs).

由于闪烁探测器是实现成像或辐射测量的核心器件,其增益参数将直接影响辐射测量的准确性。然而,由于闪烁晶体的个体光输出(光输出是指闪烁晶体吸收单位能量的电离射线转换为光子的数量)之间存在差异,这种差异将会引起闪烁探测器的增益变化,尤其是以硅光电倍增器为光电器件的闪烁探测器,其增益对温度极度敏感,在-20~50℃温度范围下增益可相差56%以上,严重影响系统的准确性。因此,实际使用中需要对闪烁探测器的增益进行校正。Since the scintillation detector is the core device for imaging or radiation measurement, its gain parameters will directly affect the accuracy of radiation measurement. However, due to differences in the individual light output of scintillation crystals (light output refers to the number of ionizing rays absorbed by scintillation crystals per unit energy and converted into photons), this difference will cause changes in the gain of scintillation detectors, especially in silicon The photomultiplier is the scintillation detector of the photoelectric device, its gain is extremely sensitive to temperature, and the gain can vary by more than 56% in the temperature range of -20 to 50°C, which seriously affects the accuracy of the system. Therefore, it is necessary to correct the gain of the scintillation detector in actual use.

目前,对闪烁探测器的增益进行校正的方法多为在闪烁探测器后端增加放大器,并采用多道分析设备测量闪烁探测器的能谱,从而获取测试射源的光电峰位置,再以光电峰位置作为闪烁探测器的增益,通过调整放大器的增益以弥补闪烁探测器增益变化造成的影响,使光电峰位置保持不变以实现增益的校准。At present, the method of correcting the gain of the scintillation detector is mostly to add an amplifier at the back end of the scintillation detector, and use multi-channel analysis equipment to measure the energy spectrum of the scintillation detector, so as to obtain the photoelectric peak position of the test source, and then use the photoelectric The peak position is used as the gain of the scintillation detector. By adjusting the gain of the amplifier to compensate for the influence caused by the gain change of the scintillation detector, the photoelectric peak position remains unchanged to achieve gain calibration.

虽然现有技术可通过在闪烁探测器后端增加放大器,将输出的信号进行二次放大以实现增益校正,但是,由于采用硅光电倍增器的闪烁探测器自身具有幅值相对固定的本底噪声信号,当硅光电倍增器的增益下降时,部分输出的信号将淹没于本底噪声信号中,即使在后端增加放大器,其信噪比也并不会提高,最终导致损失信号信息。其次,采用放大器后,需要测量校准射源的完整的能谱,并获取其光电峰位置以实现校准,通常其数据获取量不低于5000个事件,这将造成系统校准速度慢,硬件成本增大。再次,采用放大器后,当温度变化时需要重复校准测量流程,校准效率降低。Although the existing technology can add an amplifier at the back end of the scintillation detector to amplify the output signal twice to achieve gain correction, however, since the scintillation detector using a silicon photomultiplier itself has a relatively fixed amplitude noise floor Signal, when the gain of the silicon photomultiplier decreases, part of the output signal will be submerged in the background noise signal. Even if an amplifier is added at the back end, the signal-to-noise ratio will not be improved, resulting in the loss of signal information. Secondly, after the amplifier is used, it is necessary to measure the complete energy spectrum of the calibration radiation source and obtain its photoelectric peak position to achieve calibration. Usually, the data acquisition amount is not less than 5000 events, which will cause slow system calibration speed and increase hardware cost. big. Thirdly, after the amplifier is used, the calibration measurement process needs to be repeated when the temperature changes, and the calibration efficiency is reduced.

实用新型内容Utility model content

本实用新型的目的是提供一种闪烁探测器的增益校正装置,从而解决现有技术中闪烁探测器的增益校正速度慢、校准效率低且成本较高的问题。The purpose of the utility model is to provide a gain correction device of a scintillation detector, so as to solve the problems of slow gain correction speed, low calibration efficiency and high cost of the scintillation detector in the prior art.

为了解决上述技术问题,本实用新型的技术方案是提供一种闪烁探测器的增益校正装置,闪烁探测器的增益G、温度t和电压x之间满足增益温度电压方程G(x,t)=at+bx+c,其中参数a、b、c为常数;所述增益校正方法包括以下步骤:In order to solve the above-mentioned technical problems, the technical solution of the utility model is to provide a kind of gain correction device of scintillation detector, the gain G of the scintillation detector, temperature t and voltage x satisfy the gain temperature-voltage equation G(x, t)= at+bx+c, wherein parameters a, b, c are constants; the gain correction method comprises the following steps:

第一步,确定标准闪烁探测器的增益温度电压方程,具体步骤为:The first step is to determine the gain temperature voltage equation of the standard scintillation detector, the specific steps are:

步骤S1:取一标准闪烁探测器,在温度T0和电压X0固定的情况下测量所述标准闪烁探测器的增益G0,将所述标准闪烁探测器的增益G0作为待测闪烁探测器的目标增益;Step S1: Take a standard scintillation detector, measure the gain G 0 of the standard scintillation detector when the temperature T 0 and the voltage X 0 are fixed, and use the gain G 0 of the standard scintillation detector as the scintillation detector to be tested The target gain of the device;

步骤S2:将温度固定为T0,将电压调整为X2,测量所述标准闪烁探测器的增益G2,代入所述增益温度电压方程,计算得到参数k2和p2,其中k2=b,p2=at0+c;Step S2: Fix the temperature as T 0 , adjust the voltage as X 2 , measure the gain G 2 of the standard scintillation detector, substitute it into the gain temperature-voltage equation, and calculate the parameters k 2 and p 2 , where k 2 = b,p 2 =at 0 +c;

步骤S3:将电压固定为X0,将温度调整为T1,测量标准闪烁探测器的增益G1,代入所述增益温度电压方程,计算得到参数k1和p1,其中,k1=a,p1=bx0+c;Step S3: Fix the voltage to X 0 , adjust the temperature to T 1 , measure the gain G 1 of the standard scintillation detector, substitute it into the gain temperature voltage equation, and calculate the parameters k 1 and p 1 , where k 1 =a , p 1 =bx 0 +c;

步骤S4:将参数k1、k2、p1和p2代入所述增益温度电压方程,计算得到标准闪烁探测器的参数a、b和c,从而确定标准闪烁探测器的增益温度电压方程为:Step S4 : Substituting the parameters k1 , k2, p1 and p2 into the gain temperature-voltage equation, calculating the parameters a, b and c of the standard scintillation detector, thereby determining the gain temperature-voltage equation of the standard scintillation detector as:

G(x,t)=at+bx+cG(x,t)=at+bx+c

步骤S5:当目标增益为G0时,根据增益温度电压方程可确定所述闪烁探测器的电压x和温度t之间的关系为:Step S5: When the target gain is G0, the relationship between the voltage x and the temperature t of the scintillation detector can be determined according to the gain temperature voltage equation as:

x=(G0-at-c)/bx=(G 0 -at-c)/b

第二步,测量待测闪烁探测器与所述标准闪烁探测器的增益差,获取待测闪烁探测器在所述目标增益条件下的电压温度方程;The second step is to measure the gain difference between the scintillation detector to be tested and the standard scintillation detector, and obtain the voltage temperature equation of the scintillation detector to be tested under the target gain condition;

第三步,将所述第二步中获得的电压温度方程作为校正的参考,根据待测闪烁探测器的实测温度计算得到对应的校正电压,根据所述校正电压改变所述闪烁探测器的电压以实现待测闪烁探测器的增益校正。The third step is to use the voltage-temperature equation obtained in the second step as a reference for correction, calculate the corresponding correction voltage according to the measured temperature of the scintillation detector to be tested, and change the voltage of the scintillation detector according to the correction voltage In order to realize the gain correction of the scintillation detector under test.

第二步的具体步骤如下:The specific steps of the second step are as follows:

步骤S6:调整温度为T0、电压为X0,测量待测闪烁探测器的增益G',则待测闪烁探测器的增益温度电压方程为:Step S6: Adjust the temperature to T 0 and the voltage to X 0 , measure the gain G' of the scintillation detector to be tested, then the gain temperature-voltage equation of the scintillation detector to be tested is:

G(x,t)=at+bx+c+(G'-G0);G(x,t)=at+bx+c+(G'-G 0 );

步骤S7:当目标增益为G0时,待测闪烁探测器的电压温度方程为:Step S7: When the target gain is G0, the voltage-temperature equation of the scintillation detector to be tested is :

x=(-at-c+2G0-G')/b。x=(-at-c+2G 0 -G')/b.

根据本实用新型的一个实施例,利用温度传感器得到待测闪烁探测器表面的实测温度,利用单片微型计算机计算得到对应的所述校正电压。According to an embodiment of the present invention, a temperature sensor is used to obtain the measured temperature on the surface of the scintillation detector to be tested, and a single-chip microcomputer is used to calculate and obtain the corresponding correction voltage.

对于同尺寸同规格的闪烁探测器,第一步只需执行一次,其他待测的闪烁探测器执行第二步以获取目标增益下的电压温度方程。For scintillation detectors with the same size and specifications, the first step only needs to be performed once, and other scintillation detectors to be tested perform the second step to obtain the voltage-temperature equation at the target gain.

本实用新型提供的闪烁探测器的增益校正装置,闪烁探测器包括相互耦合的闪烁晶体和光电器件,增益校正装置包括:校准射源,所述闪烁晶体接收所述校准射源发出的电离辐射射线并将所述电离辐射射线转换为可见光,所述光电器件将所述可见光转换为模拟电压信号;至少两路比较器,每一路所述比较器均与所述光电器件通信连接以将不同能量段的所述模拟电压信号转换为数字脉冲信号;计数模块,所述计数模块分别与每一路所述比较器通信连接以接收每一路所述比较器发送的数字脉冲信号,所述计数模块同时测量所述数字脉冲信号的计数率;温度传感器,所述温度传感器设置于所述光电器件外侧表面以实测温度数据;单片微型计算机,所述单片微型计算机与所述计数模块通信连接以接收所述计数率,所述单片微型计算机还与所述温度传感器通信连接以接收所述实测温度数据,所述单片微型计算机根据所述计数率和所述实测温度数据计算目标增益以及校正电压;以及高压电源,所述高压电源与所述单片微型计算机连接以接收所述校正电压,所述高压电源还与所述光电器件连接以根据所述校正电压实现所述光电器件的增益校正。The utility model provides a gain correction device for a scintillation detector. The scintillation detector includes a scintillation crystal and a photoelectric device coupled to each other. The gain correction device includes: a calibration radiation source, and the scintillation crystal receives the ionizing radiation emitted by the calibration radiation source And converting the ionizing radiation into visible light, the photoelectric device converts the visible light into an analog voltage signal; at least two comparators, each of which is connected to the photoelectric device in communication to convert different energy segments The analog voltage signal is converted into a digital pulse signal; a counting module, the counting module is respectively connected to the comparator of each road to receive the digital pulse signal sent by the comparator of each road, and the counting module measures the digital pulse signal at the same time The counting rate of the digital pulse signal; a temperature sensor, the temperature sensor is arranged on the outer surface of the photoelectric device to measure the temperature data; a single-chip microcomputer, the single-chip microcomputer communicates with the counting module to receive the counting rate, the single-chip microcomputer is also communicatively connected with the temperature sensor to receive the measured temperature data, and the single-chip microcomputer calculates a target gain and a correction voltage according to the counting rate and the measured temperature data; and A high-voltage power supply, the high-voltage power supply is connected to the single-chip microcomputer to receive the correction voltage, and the high-voltage power supply is also connected to the photoelectric device to realize gain correction of the photoelectric device according to the correction voltage.

校准射源采用单能射源。The calibration radiation source adopts single-energy radiation source.

校准射源采用的放射性核素为Cs-137、Co-60或者Eu-152。The radionuclide used in the calibration radioactive source is Cs-137, Co-60 or Eu-152.

对同种闪烁探测器进行校准时,所述校准射源与所述闪烁晶体之间的相对位置保持固定。When calibrating the scintillation detector of the same kind, the relative position between the calibration radiation source and the scintillation crystal remains fixed.

多路比较器包括两路比较器,所述两路比较器分别与所述光电器件和所述计算模块通信连接。The multi-way comparator includes two-way comparators, and the two-way comparators are respectively connected in communication with the photoelectric device and the computing module.

光电器件为硅光电倍增器。The optoelectronic device is a silicon photomultiplier.

本实用新型提供的闪烁探测器的增益校正装置,能够从闪烁探测器端直接进行增益校准,解决了信息缺失的问题,使用多路比较器替代多道分析仪,简化了校准过程的测量设备需求,加快了校准速度。同时,本实用新型建立了闪烁探测器的增益和温度、电压的数学模型,可以根据温度直接调整增益,无需重新测量,提高了增益校正的效率。The gain calibration device of the scintillation detector provided by the utility model can directly perform gain calibration from the scintillation detector end, which solves the problem of missing information, uses a multi-channel comparator instead of a multi-channel analyzer, and simplifies the measurement equipment requirements in the calibration process , to speed up the calibration. At the same time, the utility model establishes a mathematical model of the gain, temperature and voltage of the scintillation detector, and the gain can be directly adjusted according to the temperature without re-measurement, thus improving the efficiency of gain correction.

附图说明Description of drawings

图1是根据本实用新型的一个实施例的闪烁探测器的增益校正装置的能量分段示意图;Fig. 1 is a schematic diagram of energy segmentation of a gain correction device of a scintillation detector according to an embodiment of the present invention;

图2是根据本实用新型的一个实施例的闪烁探测器的增益校正装置的增益与温度的关系示意图;2 is a schematic diagram of the relationship between the gain and temperature of the gain correction device of the scintillation detector according to an embodiment of the present invention;

图3是根据本实用新型的一个优选实施例的闪烁探测器的增益校正装置的校正流程示意图;Fig. 3 is a schematic diagram of the correction process of the gain correction device of the scintillation detector according to a preferred embodiment of the present invention;

图4是根据本实用新型的一个实施例的闪烁探测器的增益校正装置的系统示意图;Fig. 4 is a system schematic diagram of a gain correction device of a scintillation detector according to an embodiment of the present invention;

图5是根据本实用新型的一个实施例的闪烁探测器的增益校正装置的多路比较器的布置示意图。Fig. 5 is a schematic diagram of arrangement of multiple comparators of a gain correction device for a scintillation detector according to an embodiment of the present invention.

具体实施方式detailed description

以下结合具体实施例,对本实用新型做进一步说明。应理解,以下实施例仅用于说明本实用新型而非用于限制本实用新型的范围。Below in conjunction with specific embodiment, the utility model is described further. It should be understood that the following examples are only used to illustrate the utility model but not to limit the scope of the utility model.

本实用新型中的能谱指使用闪烁探测器获取电离辐射射线的能量和数量信息,并以能量分段绘制的能量分布直方图。每一种射源都可发出几种固定能量的电离辐射射线,因此每一种射源都有相对固定的能谱形态。若采用n个不同的能量限值En将能谱划分为若干个能量段,则各个能量段内单位时间所有的脉冲计数率的比即为能量通道计数率比,比如使用3个能量限值E1、E2、E3将能谱划分为三个能量段,这三个能量段的区间分别为[E1,E2)、[E2,E3)、[E3,+∞),三个能量段内的计数率分别为CR1、CR2、CR3,则能量通道计数率比为CR1:CR2:CR3。对于确定尺寸的闪烁晶体,其对于同种射源的能谱形态也是相对固定的,即各能量通道的计数率比是稳定的,因此不同能量段的总计数率比也是稳定的。基于以上原理,可以采用任意两个反向电压不同的比较器记录不同能量段的计数率比,以此作为校准的参考标准,并且将该不同计数率的比值作为闪烁探测器的光电器件的增益。具体地,如图1所示,Cs-137的能谱可以分为两个能量段,如图中点画线分割所示,通过上述原理可确定闪烁探测器的光电器件的增益为:The energy spectrum in the utility model refers to the energy distribution histogram drawn by energy segments by using the scintillation detector to obtain the energy and quantity information of the ionizing radiation rays. Each radiation source can emit several kinds of ionizing radiation rays with fixed energy, so each radiation source has a relatively fixed energy spectrum form. If n different energy limits E n are used to divide the energy spectrum into several energy segments, then the ratio of all pulse count rates per unit time in each energy segment is the energy channel count rate ratio, for example, using 3 energy limits E 1 , E 2 , E 3 divide the energy spectrum into three energy segments, and the intervals of these three energy segments are [E 1 , E 2 ), [E 2 , E 3 ), [E 3 , +∞) , the counting rates in the three energy segments are CR 1 , CR 2 , and CR 3 respectively, and the counting rate ratio of the energy channel is CR 1 :CR 2 :CR 3 . For a scintillation crystal with a certain size, its energy spectrum form for the same radiation source is also relatively fixed, that is, the count rate ratio of each energy channel is stable, so the total count rate ratio of different energy segments is also stable. Based on the above principles, any two comparators with different reverse voltages can be used to record the count rate ratio of different energy segments as a reference standard for calibration, and the ratio of different count rates can be used as the gain of the photoelectric device of the scintillation detector . Specifically, as shown in Figure 1, the energy spectrum of Cs-137 can be divided into two energy segments, as shown in the dotted line division in the figure, the gain of the optoelectronic device of the scintillation detector can be determined by the above principle as:

G=CountRate2/CountRate1G=CountRate2/CountRate1

其中,CountRate指不同通道的比较器所记录的计数率,CountRate1为能量限值较低的比较器1的计数率,CountRate2为能量限值较高的比较器2的计数率。Among them, CountRate refers to the counting rate recorded by the comparators of different channels, CountRate1 is the counting rate of comparator 1 with a lower energy limit, and CountRate2 is the counting rate of comparator 2 with a higher energy limit.

进一步地,图2为根据本实用新型的一个优选实施例的闪烁探测器的增益与温度的关系示意图,由图2可知,根据实际测量结果,光电器件的增益和温度基本呈一次线性关系,增益和电压也呈一次线性关系,因此,增益G和温度t、电压x之间满足如下方程:Further, Fig. 2 is a schematic diagram of the relationship between the gain and temperature of the scintillation detector according to a preferred embodiment of the present invention. It can be seen from Fig. 2 that, according to the actual measurement results, the gain and temperature of the photoelectric device are basically in a linear relationship, and the gain And the voltage also has a linear relationship, therefore, the following equation is satisfied between the gain G and the temperature t and the voltage x:

G(x,t)=at+bx+c (1)G(x,t)=at+bx+c (1)

其中,a为温度系数,b为电压系数,c为与电压和温度无关的由闪烁探测器性质决定的增益偏差常数,比如闪烁晶体和光电器件耦合引起的光损失等。Among them, a is the temperature coefficient, b is the voltage coefficient, and c is the gain deviation constant determined by the properties of the scintillation detector that is independent of voltage and temperature, such as the light loss caused by the coupling between the scintillation crystal and the optoelectronic device.

通过式(1)的关系测量获取a、b、c即可实现温度范围内的校正,具体如下:The correction within the temperature range can be realized by obtaining a, b, and c through the relationship measurement of formula (1), as follows:

第一,当温度t0固定时,可得First, when the temperature t 0 is fixed, we can get

G(x,t0)=k2x+p2 (2)G(x,t 0 )=k 2 x+p 2 (2)

其中,k2=b,p2=at0+c;where k 2 =b, p 2 =at 0 +c;

第二,当电压x0固定时,可得Second, when the voltage x 0 is fixed, we have

G(x0,t)=k1t+p1 (3)G(x 0 ,t)=k 1 t+p 1 (3)

其中,k1=a,p1=bx0+c。Wherein, k 1 =a, p 1 =bx 0 +c.

根据以上关系,结合图3可知,本实用新型进行增益校正的步骤如下:According to the above relationship, in conjunction with Fig. 3, it can be seen that the steps of the utility model for gain correction are as follows:

第一步,确定标准闪烁探测器的增益温度电压方程,以便在不同温度下实现增益校正,具体步骤为:The first step is to determine the gain temperature voltage equation of the standard scintillation detector in order to achieve gain correction at different temperatures, the specific steps are:

S1:取一标准闪烁探测器,在温度T0和电压X0固定的情况下测量标准闪烁探测器的增益G0,将标准闪烁探测器的增益G0作为其他待测闪烁探测器的目标增益;S1: Take a standard scintillation detector, measure the gain G 0 of the standard scintillation detector when the temperature T 0 and the voltage X 0 are fixed, and use the gain G 0 of the standard scintillation detector as the target gain of other scintillation detectors to be tested ;

S2:将温度固定为T0,将电压调整为X2,测量标准闪烁探测器的增益G2,代入上文中的式(2),计算得到参数k2和p2S2: Fix the temperature as T 0 , adjust the voltage as X 2 , measure the gain G 2 of the standard scintillation detector, substitute it into the formula (2) above, and calculate the parameters k 2 and p 2 ;

S3:将电压固定为X0,将温度调整为T1,测量标准闪烁探测器的增益G1,代入上文中的式(3),计算得到参数k1和p1S3: Fix the voltage to X 0 , adjust the temperature to T 1 , measure the gain G 1 of the standard scintillation detector, substitute it into the formula (3) above, and calculate the parameters k 1 and p 1 ;

S4:将参数k1、k2、p1和p2代入上文中的式(1),计算得到标准闪烁探测器的参数a、b和c,从而确定标准闪烁探测器的增益温度电压方程为:S4: Substituting the parameters k1, k2, p1 and p2 into the above formula ( 1 ) to calculate the parameters a, b and c of the standard scintillation detector, so as to determine the gain temperature voltage equation of the standard scintillation detector as:

G(x,t)=at+bx+c (1)G(x,t)=at+bx+c (1)

S5:当目标增益为G0时,根据上式可确定闪烁探测器的电压x和温度t之间的关系为:S5: When the target gain is G 0 , according to the above formula, the relationship between the voltage x and the temperature t of the scintillation detector can be determined as:

x=(G0-at-c)/bx=(G 0 -at-c)/b

第二步,在标准闪烁探测器的样品条件下测量待测闪烁探测器与标准闪烁探测器的增益差,获取待测闪烁探测器在固定的目标增益条件下的电压温度方程;此处的样品条件指第一步中固定的温度T0和电压X0,具体步骤如下:The second step is to measure the gain difference between the scintillation detector to be tested and the standard scintillation detector under the sample conditions of the standard scintillation detector, and obtain the voltage temperature equation of the scintillation detector to be tested under the fixed target gain condition; the sample here The conditions refer to the fixed temperature T 0 and voltage X 0 in the first step, and the specific steps are as follows:

S6:调整温度为T0、电压为X0,测量待测闪烁探测器的增益G',则待测闪烁探测器的增益温度电压方程为:S6: Adjust the temperature to T 0 and the voltage to X 0 , measure the gain G' of the scintillation detector to be tested, then the gain temperature-voltage equation of the scintillation detector to be tested is:

G(x,t)=at+bx+c+(G’-G0)G(x,t)=at+bx+c+(G'-G 0 )

S7:当目标增益为G0时,待测闪烁探测器的电压温度方程为:S7: When the target gain is G0, the voltage-temperature equation of the scintillation detector to be tested is :

x=(-at-c+2G0-G')/bx=(-at-c+2G 0 -G')/b

第三步,根据实际测量的待测闪烁探测器与标准闪烁探测器的增益差,将步骤S7中获得的电压温度方程作为校正的参考,利用温度传感器实测的温度计算得到对应的校正电压,单片微型计算机(MCU)根据校正电压控制高压电源改变电压以实现待测闪烁探测器的校正。In the third step, according to the actual measurement of the gain difference between the scintillation detector to be tested and the standard scintillation detector, the voltage-temperature equation obtained in step S7 is used as a reference for correction, and the corresponding correction voltage is calculated by using the temperature actually measured by the temperature sensor. On-chip microcomputer (MCU) controls the high-voltage power supply to change the voltage according to the correction voltage to realize the correction of the scintillation detector to be tested.

对于同尺寸同规格的闪烁探测器,第一步只需执行一次,也即步骤S1-S5仅需执行一次,其他待测的闪烁探测器只需按序执行后续步骤(S6-S7)即可获取目标增益下的电压温度方程。For scintillation detectors with the same size and specifications, the first step only needs to be performed once, that is, steps S1-S5 only need to be performed once, and other scintillation detectors to be tested only need to perform subsequent steps (S6-S7) in sequence Obtain the voltage temperature equation at the target gain.

需要注意的是,实际使用中实际测量的增益和目标增益之间可能存在误差,通过步骤S6-S7确定待测闪烁探测器的电压和温度关系后,通过MCU计算出校正电压并控制高压电压进行校正电压输出进行校准后,可通过执行步骤S6持续测量增益,并通过步骤S7与目标增益进行比较,若校正后的增益不符合目标增益,则重复执行步骤S6-S7并重新进行调整,直至达到要求的范围;若校正后的增益符合目标增益,则自动进行下一个待测闪烁探测器的增益校准。It should be noted that there may be errors between the actual measured gain and the target gain in actual use. After determining the relationship between the voltage and temperature of the scintillation detector to be tested through steps S6-S7, the correction voltage is calculated by the MCU and the high-voltage voltage is controlled. After the correction voltage output is calibrated, the gain can be continuously measured by performing step S6, and compared with the target gain by step S7. If the corrected gain does not meet the target gain, repeat steps S6-S7 and re-adjust until it reaches The required range; if the corrected gain meets the target gain, then the gain calibration of the next scintillation detector to be tested will be automatically performed.

因此,根据上述原理,本实用新型提供的闪烁探测器的增益校正装置的系统示意图如图4所示,由图4可知,本实用新型的闪烁探测器10的增益校正装置包括校准射源20、多路比较器30、计数模块40、单片微型计算机(MCU)50、高压电源60以及温度传感器70,其中,闪烁探测器10包括相互耦合的闪烁晶体11和光电器件12;校准射源20采用单能射源,比如Cs-137,校准射源20发出电离辐射射线,比如X射线、伽马光子、中子、α光子和β光子等;闪烁晶体11接收校准射源20发出的电离辐射射线并将该电离辐射射线转换为可见光,与闪烁晶体11耦合的光电器件12接收该可见光并将该可见光转换为模拟电压信号;多路比较器30与光电器件12通信连接并接收来自于光电器件12的模拟电压信号,多路比较器30根据不同的能量段设置将模拟电压信号转换为数字脉冲信号并发送至计数模块40;计数模块40与多路比较器30通信连接以接收数字脉冲信号,计数模块40同时测量单位时间内多路比较器30发送的数字脉冲信号的数量,也即计数率,然后将该计数率发送至MCU50;温度传感器70设置于光电器件12的表面以便准确的测量光电器件12表面的实时温度,温度传感器70将测量的实时温度数据发送至MCU50;MCU50根据接收的计数模块40发送的各路比较器30的计数率数据进行计算以获取目标增益,同时根据电压温度方程以及实时温度数据计算校正电压,MCU50确定校正电压后发送调整命令至高压电源60以将电压调整为校准所需电压,从而完成校准,控制校准操作的进行。Therefore, according to the above principles, the system schematic diagram of the gain correction device of the scintillation detector provided by the present invention is shown in Figure 4, as can be seen from Figure 4, the gain correction device of the scintillation detector 10 of the present invention includes a calibration radiation source 20, Multi-way comparator 30, counting module 40, single-chip microcomputer (MCU) 50, high-voltage power supply 60 and temperature sensor 70, wherein, scintillation detector 10 includes mutually coupled scintillation crystal 11 and photoelectric device 12; Calibration radiation source 20 adopts Single-energy radiation source, such as Cs-137, calibration radiation source 20 emits ionizing radiation rays, such as X-rays, gamma photons, neutrons, alpha photons and beta photons, etc.; scintillation crystal 11 receives the ionizing radiation radiation emitted by calibration radiation source 20 and convert the ionizing radiation into visible light, and the photoelectric device 12 coupled with the scintillation crystal 11 receives the visible light and converts the visible light into an analog voltage signal; The analog voltage signal of the multi-way comparator 30 is set to convert the analog voltage signal into a digital pulse signal according to different energy segments and sends it to the counting module 40; the counting module 40 is connected with the multi-way comparator 30 to receive the digital pulse signal, count The module 40 simultaneously measures the number of digital pulse signals sent by the multi-channel comparator 30 per unit time, that is, the count rate, and then sends the count rate to the MCU50; the temperature sensor 70 is arranged on the surface of the optoelectronic device 12 so as to accurately measure the optoelectronic device 12 the real-time temperature of the surface, the temperature sensor 70 sends the real-time temperature data measured to the MCU50; The real-time temperature data calculates the correction voltage, and after the MCU 50 determines the correction voltage, it sends an adjustment command to the high-voltage power supply 60 to adjust the voltage to the voltage required for calibration, thereby completing the calibration and controlling the calibration operation.

更具体地,图5为根据本实用新型的一个实施例的闪烁探测器的增益校正装置的多路比较器的布置示意图,其中比较器共n路,光电器件12分别与多路比较器30通信连接,即光电器件12分别与第一比较器31、第二比较器32、……,以及第n比较器通信连接,第一比较器31、第二比较器32、……,以及第n比较器分别与计数模块40通信连接。由于能谱被n个不同的能量限值划分为若干个能量段,每一路比较器相应的将各个能量段内的模拟数字信号转换为数字脉冲信号,计数模块40同时测量单位时间内每一路比较器发送的数字脉冲信号的数量并将各个通道的计数率数据发送至MCU50,通过MCU确定能量通道计数率比,进而确定目标增益。More specifically, FIG. 5 is a schematic diagram of the layout of the multiple comparators of the gain correction device of the scintillation detector according to an embodiment of the present invention, wherein there are n comparators in total, and the optoelectronic devices 12 communicate with the multiple comparators 30 respectively. connection, that is, the optoelectronic device 12 is respectively connected to the first comparator 31, the second comparator 32, ..., and the nth comparator, and the first comparator 31, the second comparator 32, ..., and the nth comparator The devices are respectively connected to the counting module 40 in communication. Since the energy spectrum is divided into several energy segments by n different energy limits, each comparator correspondingly converts the analog digital signal in each energy segment into a digital pulse signal, and the counting module 40 simultaneously measures the energy of each comparator in a unit time. The number of digital pulse signals sent by the detector and the count rate data of each channel are sent to the MCU50, and the MCU determines the count rate ratio of the energy channel, and then determines the target gain.

根据本实用新型的一个优选实施例,多路比较器30仅采用两个反向电压不同的比较器31、32,通过计数模块40记录不同能量段的计数率比,以此作为校准的参考标准,并且通过MCU将该不同计数率的比值作为闪烁探测器的增益进行校正。According to a preferred embodiment of the utility model, the multi-way comparator 30 only uses two comparators 31 and 32 with different reverse voltages, and the counting rate ratio of different energy segments is recorded by the counting module 40, as a reference standard for calibration , and the ratio of the different count rates is corrected by the MCU as the gain of the scintillation detector.

应当注意的是,由于校准射源20发出的电离辐射射线易受到周围物体的反射和折射,这将影响到闪烁晶体测量的能谱的形态,因此,需要避免校准射源20和闪烁晶体11之间有密度较大的物体阻挡,比如金属板等。同时还需注意,校准射源20与闪烁晶体11之间的相对位置应保持固定,对同种闪烁探测器进行校准时,校准射源20与闪烁晶体11之间的相对位置也应保持一致,否则将引起校准误差。It should be noted that since the ionizing radiation emitted by the calibration radiation source 20 is easily reflected and refracted by surrounding objects, this will affect the form of the energy spectrum measured by the scintillation crystal. There is a dense object in between, such as a metal plate. At the same time, it should also be noted that the relative position between the calibration radiation source 20 and the scintillation crystal 11 should be kept fixed. When calibrating the same kind of scintillation detector, the relative position between the calibration radiation source 20 and the scintillation crystal 11 should also be consistent. Failure to do so will cause calibration errors.

根据本实用新型的一个实施例,校准射源20采用单能射源,比如Cs-137、Co-60或者Eu-152,不一定是Cs-137,因为单能射源的能谱相对比较简单,可以获取比较稳定的通道计数比。应当理解的是,本实用新型的校准射源并不局限于单能射源,还可为其他类型的射源。According to an embodiment of the present invention, the calibration radiation source 20 adopts a single-energy radiation source, such as Cs-137, Co-60 or Eu-152, not necessarily Cs-137, because the energy spectrum of the single-energy radiation source is relatively simple , a relatively stable channel count ratio can be obtained. It should be understood that the calibration radiation source of the present invention is not limited to a single-energy radiation source, and may also be other types of radiation sources.

根据本实用新型的一个优选实施例,光电器件12采用硅光电倍增器(SiPM),温度传感器70紧贴SiPM安装;温度传感器70还可安装于光电器件的外壳、SiPM底面的PCB板上或者SiPM的侧面。According to a preferred embodiment of the present utility model, optoelectronic device 12 adopts silicon photomultiplier (SiPM), and temperature sensor 70 is installed close to SiPM; side.

本实用新型提供的闪烁探测器的增益校正装置,能够从闪烁探测器端实现增益校正,保证了闪烁探测器在不同的温度和不同性能的闪烁晶体条件下信噪比不变,使闪烁探测器校准后的能量探测下限不变,保持了信息的完整性。本实用新型采用两路或者多路比较器和计数器代替多道分析器,不需要测量完整的能谱即可实现增益的测量,仅需1000个事件即可测量准确的增益,相比能谱法获取增益,测量事件数量下降80%,校准速度更快。同时,本实用新型建立了光电器件的增益对温度、电压的数学模型,仅需要测量两个温度下的数据,即可实现完整温度范围的校正,校准效率更高。The gain correction device of the scintillation detector provided by the utility model can realize the gain correction from the scintillation detector end, which ensures that the signal-to-noise ratio of the scintillation detector remains unchanged under the conditions of different temperatures and scintillation crystals with different performances, and makes the scintillation detector The lower limit of energy detection after calibration remains unchanged, maintaining the integrity of information. The utility model adopts two-way or multi-way comparators and counters instead of multi-channel analyzers, and the measurement of the gain can be realized without measuring the complete energy spectrum, and the accurate gain can be measured only by 1000 events. Compared with the energy spectrum method Get the gain, the number of measurement events drops by 80%, and the calibration is faster. At the same time, the utility model establishes a mathematical model of the gain of the photoelectric device to temperature and voltage, and only needs to measure the data at two temperatures to realize the correction of the complete temperature range, and the calibration efficiency is higher.

以上所述的,仅为本实用新型的较佳实施例,并非用以限定本实用新型的范围,本实用新型的上述实施例还可以做出各种变化,比如本实用新型中对增益、温度、电压建立的模型可以使用二次或更高阶函数进行拟合。即凡是依据本实用新型申请的权利要求书及说明书内容所作的简单、等效变化与修饰,皆落入本实用新型专利的权利要求保护范围。本实用新型未详尽描述的均为常规技术内容。The above are only preferred embodiments of the present utility model, and are not intended to limit the scope of the present utility model. Various changes can also be made to the above-mentioned embodiments of the present utility model, such as the gain, temperature , Voltage Models can be fitted using quadratic or higher order functions. That is to say, all simple and equivalent changes and modifications made according to the claims of the utility model application and the contents of the description all fall within the protection scope of the claims of the utility model patent. What the utility model does not describe in detail is conventional technical contents.

Claims (6)

1.一种闪烁探测器的增益校正装置,所述闪烁探测器包括相互耦合的闪烁晶体和光电器件,其特征在于,所述增益校正装置包括:1. A gain correction device for a scintillation detector, said scintillation detector comprising scintillation crystals and optoelectronic devices coupled to each other, characterized in that said gain correction device comprises: 校准射源,所述闪烁晶体接收所述校准射源发出的电离辐射射线并将所述电离辐射射线转换为可见光,所述光电器件将所述可见光转换为模拟电压信号;a calibration radiation source, the scintillation crystal receives the ionizing radiation emitted by the calibration radiation source and converts the ionizing radiation into visible light, and the photoelectric device converts the visible light into an analog voltage signal; 至少两路比较器,每一路所述比较器均与所述光电器件通信连接以将不同能量段的所述模拟电压信号转换为数字脉冲信号;At least two comparators, each of which is communicatively connected to the optoelectronic device to convert the analog voltage signals of different energy segments into digital pulse signals; 计数模块,所述计数模块分别与每一路所述比较器通信连接以接收每一路所述比较器发送的数字脉冲信号,所述计数模块同时测量所述数字脉冲信号的计数率;A counting module, the counting module is connected in communication with each of the comparators to receive the digital pulse signal sent by each of the comparators, and the counting module simultaneously measures the count rate of the digital pulse signal; 温度传感器,所述温度传感器设置于所述光电器件外侧以实测温度数据;A temperature sensor, the temperature sensor is arranged outside the photoelectric device to measure temperature data; 单片微型计算机,所述单片微型计算机与所述计数模块通信连接以接收所述计数率,所述单片微型计算机还与所述温度传感器通信连接以接收所述实测温度数据,所述单片微型计算机根据所述计数率和所述实测温度数据计算目标增益以及校正电压;以及A single-chip microcomputer, the single-chip microcomputer communicates with the counting module to receive the count rate, and the single-chip microcomputer communicates with the temperature sensor to receive the measured temperature data, the single-chip microcomputer The on-chip microcomputer calculates a target gain and a correction voltage according to the count rate and the measured temperature data; and 高压电源,所述高压电源与所述单片微型计算机连接以接收所述校正电压,所述高压电源还与所述光电器件连接以根据所述校正电压实现所述光电器件的增益校正。A high-voltage power supply, the high-voltage power supply is connected to the single-chip microcomputer to receive the correction voltage, and the high-voltage power supply is also connected to the photoelectric device to realize gain correction of the photoelectric device according to the correction voltage. 2.根据权利要求1所述的闪烁探测器的增益校正装置,其特征在于,所述校准射源采用单能射源。2 . The gain correction device for a scintillation detector according to claim 1 , wherein the calibration radiation source is a single-energy radiation source. 3 . 3.根据权利要求2所述的闪烁探测器的增益校正装置,其特征在于,所述校准射源采用的放射性核素为Cs-137、Co-60或者Eu-152。3. The gain correction device of scintillation detector according to claim 2, characterized in that the radionuclide used in the calibration radiation source is Cs-137, Co-60 or Eu-152. 4.根据权利要求1所述的闪烁探测器的增益校正装置,其特征在于,对同种闪烁探测器进行校准时,所述校准射源与所述闪烁晶体之间的相对位置保持固定。4 . The gain correction device for scintillation detectors according to claim 1 , wherein when calibrating the scintillation detectors of the same type, the relative position between the calibration radiation source and the scintillation crystal remains fixed. 5.根据权利要求1所述的闪烁探测器的增益校正装置,其特征在于,所述比较器包括两路比较器,两路所述比较器分别与所述光电器件和所述计数模块通信连接。5. The gain correction device of the scintillation detector according to claim 1, wherein the comparator comprises two comparators, and the two comparators are connected in communication with the photoelectric device and the counting module respectively . 6.根据权利要求1所述的闪烁探测器的增益校正装置,其特征在于,所述光电器件为硅光电倍增器。6. The gain correction device of scintillation detector according to claim 1, characterized in that, the photoelectric device is a silicon photomultiplier.
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107247284A (en) * 2017-07-25 2017-10-13 苏州瑞派宁科技有限公司 The gain correcting device and method of a kind of scintillation detector
CN114460623A (en) * 2020-11-10 2022-05-10 天津市通透医疗科技有限公司 SiPM bias control circuit for two-end readout DOI PET

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107247284A (en) * 2017-07-25 2017-10-13 苏州瑞派宁科技有限公司 The gain correcting device and method of a kind of scintillation detector
WO2019019451A1 (en) * 2017-07-25 2019-01-31 苏州瑞派宁科技有限公司 Gain correction apparatus and method for scintillation detector
CN107247284B (en) * 2017-07-25 2023-09-22 苏州瑞派宁科技有限公司 Gain correction device and method for scintillation detector
CN114460623A (en) * 2020-11-10 2022-05-10 天津市通透医疗科技有限公司 SiPM bias control circuit for two-end readout DOI PET

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