CN206852604U - A kind of capsule endoscope system for gastrointestinal protuberant lesions examination - Google Patents

A kind of capsule endoscope system for gastrointestinal protuberant lesions examination Download PDF

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CN206852604U
CN206852604U CN201621152904.7U CN201621152904U CN206852604U CN 206852604 U CN206852604 U CN 206852604U CN 201621152904 U CN201621152904 U CN 201621152904U CN 206852604 U CN206852604 U CN 206852604U
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radiation
capsule
capsule endoscope
ray
mobile terminal
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廖专
李兆申
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Second Military Medical University SMMU
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Second Military Medical University SMMU
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Abstract

It the utility model is related to a kind of capsule endoscope system for gastrointestinal protuberant lesions examination, including ray scanning formula capsule endoscope, mobile terminal records instrument, data processing terminal;The ray scanning formula capsule endoscope includes capsule-type shell, miniature X ray generator, radiation detector, collimator, motion sensor, battery, Bluetooth communication modules, radiation proof shield, control circuit, piezoelectricity micro-displacement brake, displacement bar.Advantage:1st, capsule endoscope system of the present utility model is easy to use, and patient is swallowing capsule, connecting mobile terminal records instrument, can normal activity, exhaust after capsule battery or remove data logger from after anus discharge, that is, complete to check.2nd, ray scanning formula capsule endoscope of the present utility model includes capsule-type shell, miniature X ray generator, radiation detector, x-ray photon can be launched in the motion process of capsule in the gastrointestinal tract and detected, so as to efficient, the carry out Alimentary tract disease examination of quick-speed large-scale.

Description

A kind of capsule endoscope system for gastrointestinal protuberant lesions examination
Technical field
Technical field of medical instruments is the utility model is related to, is that a kind of gastrointestinal protuberant lesions that are used for sieve specifically The capsule endoscope system looked into.
Background technology
Colorectal cancer is commonly called as colorectal cancer, is that the cancer in colon occurs.Colon is one section of intestinal tube critically important in human body, its Effect is to absorb moisture and some other material in the swill digested and assimilated by small intestine, and these residues are finally become Into excrement, and finally excrete.Polyp of colon, it is the lesion of colonic mucosal surface protuberance property, generally, is grown in intestinal tube An interior hyperplastic dermopathy, polyp of colon are often gradually grown up over time.Existing evidence shows, almost all of colon cancer All originate from polyp of colon.Therefore the benign polypus for also very little being extractd under colonoscopy is one of effective measures for being capable of pre- anti-cancer. The prevention emphasis of colorectal cancer essentially consists in increasing generaI investigation and examination dynamics, and generaI investigation can improve colorectal cancer early diagnosis rate, reduce the death rate. At present, the examination for colorectal cancer mainly includes the content of five aspects:1st, medical history is collected;2nd, digital rectal examination;3rd, routine test (blood Conventional, stool OB);4th, CEA is detected;5th, enteroscopy.Enteroscopy is that colonoscopy is followed chamber and is inserted to ileocecus by per anum, from mucous membrane The inspection method of colonic pathological change is observed in side, is the optimal selection of current diagnosis colorectal mucosa lesion.Enteroscopy is by being installed on The electro-photographic probe of colonoscopy front end by the image transmitting of mucous membrane of colon in electronic computer processing center, after be shown in monitor On screen, the minor variations of colorectal mucosa can be observed.But patient will bear affliction during enteroscopy, and the hidden of perforation be present Suffer from.Pain when although existing Painless can avoid checking, Painless risk is big, has anesthetic accident and causes dead disease Example happens occasionally.
Capsule endoscope full name is that " intelligent capsule digestive tract endoscope system " is also known as " Medical wireless scope ", in recent years should be For a kind of new-type digestion endoscope of clinic, operation principle is that person under inspection passes through oral built-in shooting and signal transmitting apparatus Intelligent capsule, it is allowed to motion and shooting image, doctor in alimentary canal by alimentary canal creep and utilizes external image recorder And image workstation, the whole alimentary canal situation of person under inspection is understood, so as to make diagnosis to its state of an illness.Capsule endoscope, which has, to be checked Convenience, hurtless measure, without wire, no pain, without cross-infection, do not influence the advantages that normal work of patient, extend alimentary canal The visual field of inspection, overcome poor resistance possessed by traditional plug-in type scope, be not suitable for oldaged physically weak and the state of an illness is critical The defects of.
Chinese patent 2013102959808, a kind of multi-functional capsule endoscope system suitable in alimentary canal is disclosed, Including capsule endoscope, external work station and Portable magnetic volume array;Described capsule endoscope, external work station and portable Magnet array forms a system by the sensing in magnetic field and the transmission of wireless signal.Portable magnetic volume array of the present utility model It can be adjusted according to actual position to be seen, conveniently, safely, effectively solve conventional capsule endoscope positions without the legal time The problem of, by the integration of pH sensor, realize and the timing pH value of privileged site in alimentary canal is detected;Meanwhile use Narrow ripple LED light powered lighting arrangement can strengthen the observation to the microstructure pattern of mucomembranous surface, accelerate to glue gastrointestinal system The difference of the tumour on film surface and non-tumour diagnoses.Chinese patent 2005100570398, disclose a kind of intelligence of three-dimensional imaging Capsule type digestive tract endoscope, including a pair of opticators and camera module, each camera module include imaging sensor, colour Processor, realtime graphic condensing encoder and interface circuit;Wherein imaging sensor carries out signal signal after analog-to-digital conversion It is connected to color processor and carries out color treatments, by UART the or I2C ends of interface circuit after image compression encoder compresses Mouthful be connected with microprocessor, then be connected through microprocessor with RF receiving and transmission module, from RF receiving and transmission module by antenna to external Information is sent, and control instruction is received by RF receiving and transmission module, and after being handled by microprocessor the instruction of receiving By the working method and working condition of I/O mouths connection LED illumination array, image sensor and RF receiving and transmission module.It is however, above-mentioned Technical scheme uses LED light powered lighting arrangement shooting image in alimentary canal, but this mode is easily by colonic contents Interference, it is difficult to it was observed that, viewing blind zone be present, shooting in the gastrointestinal tract has randomness in capped polyp of colon;And After inspection terminates, the medical personnel for generally requiring specialty screen analysis, time and effort consuming to a large amount of photos of shooting.
The content of the invention
The purpose of this utility model is to be directed to deficiency of the prior art, there is provided one kind is used for gastrointestinal protuberant lesions and sieved The capsule endoscope system looked into.
To achieve the above object, the utility model adopts the technical scheme that:
A kind of capsule endoscope system for gastrointestinal protuberant lesions examination, including ray scanning formula capsule endoscope (1), Mobile terminal records instrument (3), data processing terminal (4);
The ray scanning formula capsule endoscope (1) includes capsule-type shell (11), miniature X ray generator (12), radiation Detector (13), collimator (14), motion sensor (15), battery (16), Bluetooth communication modules (17), radiation proof shield (18), area (22), radiation closing area are opened in control circuit (19), piezoelectricity micro-displacement brake (20), displacement bar (21), radiation (23), radiation window (24);The capsule-type shell (11) a diameter of 16mm, 17mm, 18mm, 19mm or 20mm, length are 31mm、32mm、33mm、34mm、35mm;The radiation proof shield (18) is hollow spherical, is made up of lead or tungsten material, anti-spoke Penetrate shield (18) and share two, be separately positioned on up and down in two chambers of capsule-type shell (11), in radiation proof shield (18) Area (22) are opened provided with radiation and area (23) are closed in radiation;It is described by radiation open area (22) centered on, along ray scanning formula glue Uniform ring is around 4-8 collimator (14) of distribution on the cross section of intracapsular mirror (1), when miniature X ray generator (12) is in radiation When opening area (22), miniature X ray generator (12) is by collimator (14) and radiation window (24) to external emission X ray spoke Penetrate;The miniature X ray generator (12) shares two, is separately positioned on up and down in two radiation proof shields (18), miniature X is penetrated Line generator (12) is fixed on displacement bar (21);The displacement bar (21) is connected with piezoelectricity micro-displacement brake (20), works as pressure When electric micro-displacement brake (20) does not receive piezoelectric signal, piezoelectricity micro-displacement brake (20) is in stable state, on displacement bar (21) The radiation that corresponds in radiation proof shield (18) of miniature X ray generator (12) close area (23), now ray scanning formula glue Intracapsular mirror (1) is not to external emission X-ray radiation;When piezoelectricity micro-displacement brake (20) receives piezoelectric signal, piezoelectricity microbit Move brake (20) and be in excitation state, the miniature X ray generator (12) on displacement bar (21) corresponds to radiation proof shield (18) Area (22) are opened in interior radiation, and now ray scanning formula capsule endoscope (1) outside capsule to sending X-ray radiation;
The motion sensor (15) is arranged in control circuit (19), and motion sensor (15) can sensitive scanning formula capsule Scope (1) motion conditions in human colon, when capsule moves, the motion that motion sensor (15) is sensed is converted to Electric signal passes to piezoelectricity micro-displacement brake (20);Bluetooth communication modules in the ray scanning formula capsule endoscope (1) (17) it is connected with mobile terminal records instrument (3) by Bluetooth communication, mobile terminal records instrument (3) is taken by wireless network and high in the clouds Business device communication connection, is connected between cloud server and data processing terminal (4) by network service;The radiation detector (13) it is arranged on the inner surface of capsule-type shell (11) and is connected with control circuit (19), radiation detector (13) is to what is sensed Backward compton scattering is counted, and count information is transferred into mobile terminal records instrument by Bluetooth communication modules (17) (3), mobile terminal records instrument (3) receives the count information obtained out of ray scanning formula capsule endoscope (1), and the counting is believed Breath data, which are uploaded in cloud server, to be preserved, and data processing terminal (4) downloads count information from cloud server automatically Data.
Further, the mobile terminal records instrument (3) includes power supply (31), receiving unit (32), single-chip microcomputer (33), data Memory module (34), antenna (35), controller (36), bandage (37), the power supply (31), receiving unit (32), single-chip microcomputer (33), data memory module (34) is linked in sequence, and antenna (35) is connected with single-chip microcomputer (33), and the single-chip microcomputer (33) receives reception Stored after the count information data-signal of unit (32) together with time tag in data memory module (34);It is described to receive list First (32) receive the count information data of Bluetooth communication modules (17) transmission by Bluetooth communication, pass through the place of single-chip microcomputer (33) Reason, the data is stored in data memory module (34) together with time tag, while the data are led to together with time tag Cross antenna (35) to communicate to connect with cloud server, downloaded for data processing terminal (4).
Further, the mobile terminal records instrument (3) has circular housing, institute's power supply (31), receiving unit (32), monolithic Machine (33), data memory module (34), antenna (35) are fixed in circular housing.
Further, control circuit (19) is fixed in capsule-type shell (11), displacement bar (20), motion sensor (15), Battery (16), Bluetooth communication modules (17), piezoelectricity micro-displacement brake (20) are fixed in control circuit (19).
Further, the data processing terminal (4) is tablet personal computer or mobile phone.
Further, the surface of the capsule-type shell (11) is additionally provided with lubricant coating.
The utility model advantage is:
1st, capsule endoscope system of the present utility model is easy to use, and patient is swallowing capsule, connecting mobile terminal records Instrument, can normal activity, exhaust after capsule battery or remove data logger from after anus discharge, that is, complete to check.
2nd, ray scanning formula capsule endoscope of the present utility model includes capsule-type shell, miniature X ray generator, radiation spy Device is surveyed, the radiation generator and detector included in capsule are as photon is launched in the motion of capsule in the gastrointestinal tract and carries out Detection, so as to efficient, the carry out Alimentary tract disease examination of quick-speed large-scale.
3rd, the data that capsule endoscope gathers are transferred to and set mobile terminal records instrument by the utility model by Bluetooth communication In, further upload and preserved into cloud server, data processing terminal downloads count information from cloud server automatically Data, by software processing, the counting rate and the curve of time of two dimension are drawn, medical personnel are according to the calibration curve information, differentiation trouble The possibility of polyp of colon or protrusion lesion be present in person's colon.Design of the present utility model reads detection process and result Process is taken to separate, patient is in or the working time can complete to check.
4th, X-ray emitter is arranged to have the Open-closure of motional induction to radiate motion structure, glue by the utility model Intracapsular including motion sensor, motion sensor is used to induce the capsule motion conditions in enteron aisle, when motion sensor senses Wriggled to capsule in the big enteral of patient, motion sensor sends signal instruction and gives piezoelectricity micro-displacement brake, piezoelectricity micro-displacement system Dynamic device drive displacement bar movement, and radiation source is moved to radiation and opens region, now radiation source sends X ray;Work as kinesthesia Device is answered not sense the movement (motion) of capsule, brake homing, radiation source is moved to spoke in the presence of brake Penetrate and close region, now radiation source does not send X ray.Design control capsule only sends radiation in special time and penetrated Line, greatly reduce patient by the time radiated.
5th, capsule-type case surface of the present utility model is additionally provided with lubricant coating, and lubricant coating can water in aqueous environment Change forms water-swellable gel, and the gel is avoided that capsule directly contacts in enteron aisle in motion process with enteron aisle inwall, significantly The friction between surface both is reduced, alleviates the damage to tissue.
6th, capsule-type case surface of the present utility model is additionally provided with lubricant coating, and the lubricant coating has good lubrication Property, and adhesive ability is strong, after 80 frictions lubricity do not reduce significantly.
Brief description of the drawings
Accompanying drawing 1 is ray scanning formula capsule endoscope structural representation of the present utility model.
Accompanying drawing 2 is mobile terminal records instrument structural representation of the present utility model.
Accompanying drawing 3 is illustraton of model of the utility model ray scanning formula capsule in colon.
Embodiment
With reference to embodiment, the utility model is expanded on further.It should be understood that these embodiments are merely to illustrate The utility model rather than limitation the scope of the utility model.In addition, it is to be understood that reading in the utility model record After appearance, those skilled in the art can make various changes or modifications to the utility model, and these equivalent form of values equally fall within this Apply for appended claims limited range.
The reference and part being related in accompanying drawing are as follows:
1. ray scanning formula capsule endoscope, 11. capsule-type shells, 12. miniature X ray generators, 13. radiation detectors, 14. collimator, 15. motion sensors, 16. batteries, 17. Bluetooth communication modules, 18. radiation proof shields, 19. control circuits, 20. Area is opened in piezoelectricity micro-displacement brake, 21. displacement bars, 22. radiation, and area, 24. radiation windows, 3. mobile terminals are closed in 23. radiation Recorder, 31. power supplys, 32. receiving units, 33. single-chip microcomputers, 34. data memory modules, 35. antennas, 36. controllers, 37. tie up Band, 4. data processing terminals.
The ray scanning formula capsule endoscope system of the present utility model of embodiment 1
Fig. 1-Fig. 2 is referred to, accompanying drawing 1 is ray scanning formula capsule endoscope structural representation of the present utility model, and accompanying drawing 2 is Mobile terminal records instrument structural representation of the present utility model.The capsule endoscope system include ray scanning formula capsule endoscope 1, Mobile terminal records instrument 3, data processing terminal 4;The ray scanning formula capsule endoscope 1 includes capsule-type shell 11, miniature X is penetrated Line generator 12, radiation detector 13, collimator 14, motion sensor 15, battery 16, Bluetooth communication modules 17, radiation proof shield Area 22, radiation closing area 23, rediation aperture are opened in cover 18, control circuit 19, piezoelectricity micro-displacement brake 20, displacement bar 21, radiation Mouth 24;The capsule-type shell (11) a diameter of 16mm, 17mm, 18mm, 19mm or 20mm, length 31mm, 32mm, 33mm, 34mm or 35mm;The radiation proof shield 18 is hollow spherical, is made up of lead or tungsten material, radiation proof shield 18 shares two Individual, be separately positioned on capsule-type shell 11 is provided with radiation unlatching area 22 and spoke up and down in two chambers, in radiation proof shield 18 Penetrate and close area 23;It is described by radiation open area 22 centered on, along the cross section of ray scanning formula capsule endoscope 1 uniform ring around point 4-8 collimator of cloth 14, when miniature X ray generator 12, which is in radiation, opens area 22, miniature X ray generator 12 passes through standard Straight instrument 14 and radiation window 24 are to external emission X-ray radiation;The miniature X ray generator 12 shares two, sets respectively In upper and lower two radiation proof shields 18, miniature X ray generator 12 is fixed on displacement bar 21;The displacement bar 21 and piezoelectricity Micro-displacement brake 20 connects, when piezoelectricity micro-displacement brake 20 does not receive piezoelectric signal, at piezoelectricity micro-displacement brake 20 Area 23 is closed in the radiation that the miniature X ray generator 12 in stable state, displacement bar 21 corresponds in radiation proof shield 18, is now penetrated Line scan-type capsule endoscope 1 is not to external emission X-ray radiation;When piezoelectricity micro-displacement brake 20 receives piezoelectric signal, pressure Electric micro-displacement brake 20 is in excitation state, and the miniature X ray generator 12 on displacement bar 21 corresponds in radiation proof shield 18 Radiation open area 22, now ray scanning formula capsule endoscope 1 outside capsule to sending X-ray radiation;The motion sensor 15 are arranged in control circuit 19, the motion conditions in human colon of the energy sensitive scanning formula of motion sensor 15 capsule endoscope 1, when When capsule moves, motion that motion sensor 15 is sensed is converted to electric signal and passes to piezoelectricity micro-displacement brake 20; Bluetooth communication modules 17 in the ray scanning formula capsule endoscope 1 are connected with mobile terminal records instrument 3 by Bluetooth communication, are moved Dynamic terminal recorder 3 is communicated to connect by wireless network and cloud server, is led between cloud server and data processing terminal 4 Cross network service connection;The radiation detector 13 is arranged on the inner surface of capsule-type shell 11 and is connected with control circuit 19, Radiation detector 13 is counted to the backward compton scattering sensed, and count information is passed through into Bluetooth communication modules 17 Mobile terminal records instrument 3 is transferred to, mobile terminal records instrument 3 receives the counting letter obtained out of ray scanning formula capsule endoscope 1 Breath, and the count information data are uploaded in cloud server and preserved, data processing terminal 4 is automatically from cloud server Download count information data.
The mobile terminal records instrument 3 includes power supply 31, receiving unit 32, single-chip microcomputer 33, data memory module 34, antenna 35th, controller 36, bandage 37, the power supply 31, receiving unit 32, single-chip microcomputer 33, data memory module 34 are linked in sequence, antenna 35 are connected with single-chip microcomputer 33, and the single-chip microcomputer 33 is received after the count information data-signal of receiving unit 32 together with time tag Store in data memory module 34;The receiving unit 32 receives the counting of the transmission of Bluetooth communication modules 17 by Bluetooth communication Information data, by the processing of single-chip microcomputer 33, the data are stored in data memory module 34 together with time tag, simultaneously The data are communicated to connect together with time tag by antenna 35 and cloud server, are downloaded for data processing terminal 4.At data Manage terminal 4, by software processing, can draw two-dimentional counting rate and the curve of time, medical personnel's root according to the data of download According to the calibration curve information, differentiate that patient's colon has the possibility of polyp of colon or protrusion lesion.
Patient takes contrast agent before checking, contrast agent flows through intestines and stomach and discharged together with excreta, and contrast agent is basic It is not absorbed into blood.After contrast agent takes 1-5 hours, patient swallow's ray scanning formula capsule endoscope of the present utility model 1, when capsule is passed through in gastrointestinal tract, the miniature X ray generator radiation X ray in capsule, now intestinal walls, enteron aisle content Thing and contrast agent, enteron aisle outside organization serve as the scattering medium of radiation by Compton scattering, and the photon of scattering passes through enteron aisle Content and contrast agent return to be detected by the radiation detector 13 of the inner surface of capsule-type shell 11, is detected within the unit interval The distance of the photon flux of return and radiation detector 13 and colon wall is into inverse relationship.As shown in figure 3, Fig. 3 illustrates glue Capsule is in the model of colon, and due to the presence of contrast agent, the intestinal contents containing contrast agent is not easy to be penetrated by X ray, therefore works as When capsule is in B location (position corresponding to polyp of colon), the backward compton scattering counting rate that detector is detected will Higher than the counting rate when capsule is located at location A.Therefore the backward compton scattering counting rate detected according to detector Change with time, can be evaluated whether detector the distance between to colon wall, thus analyze the colonic segment exist polyp of colon or The possibility of protrusion lesion.
The motion sensor 15 can sense the motion conditions for indicating capsule in intestines and stomach, when motion sensor 15 senses Wriggled to capsule in the big enteral of patient, motion sensor 15 sends electric signal and instructed to piezoelectricity micro-displacement brake 20, piezoelectric micromotor Miniature X ray generator 12 is moved to radiation and opens area 22 by displacement brake 20, and now capsule externally sends X ray.Work as fortune Dynamic sensor 15 does not sense the movement (motion) of capsule, the homing of piezoelectricity micro-displacement brake 20, now miniature X ray Generator 12 is moved to radiation in the presence of motion sensor 15 and closes area 23, and now capsule does not radiate externally.Pass through fortune Sense wriggling of the capsule in big enteral with motion sensor 15, control capsule only sends radiation within the mobile period and penetrated Line, power supply is saved, reduce patient by the flux (exposed amount) radiated.
After patient takes contrast agent, the contrast concentration of intestinal contents is equally distributed in specific region, therefore For single energy photon radiation source, the X ray-backward compton scattering projected from radiation source returns to radiation detector During, the flux of the backward compton scattering that radiation detector is detected and photon are by the distance of contrast agent into anti- Proportionate relationship.Therefore, when capsule is by with enteron aisle position corresponding to polyp of colon, the Compton that detector is detected is carried on the back Compare what is dramatically increased in scattered photon number position adjacent thereto.
Capsule reaches the movement characteristic after large intestine:The continuity that the longitudinal muscle and circular muscle of large intestine are coordinated is shunk, and makes large intestine Some stable intestinal wall contraction waves forward are formed, constantly push forward big intestinal contents.The characteristics of wriggling is that intestinal segment is filled When swollen, longitudinal muscle shrinks first, is shunk followed by circular muscle, and material is thus formed diastole preceding, shrinks posterior peristaltic wave.It is compacted It is dynamic often since hepatic flexure of colon, left hemicolon to is pushed intestinal contents with 1~2cm per minute speed.Pushed ahead during colonic peristalsis Strength is very big, is the principal mode that colon transports.The colonic contents most of the time is motionless, and every a few hours, contraction is opened Begin, colon produces pressure, and material is forwardly toward into anus extruding.In order that patient is minimized by the radiation of radiation source, spoke The source of penetrating is configured to the Open-closure radiation motion structure with motional induction, includes motion sensor, motion-sensing in capsule Device is used to induce the capsule motion conditions in enteron aisle, when motion sensor senses capsule in the big enteral wriggling of patient, motion Sensor sends signal instruction and gives piezoelectricity micro-displacement brake, the movement of piezoelectricity micro-displacement brake drive displacement bar, and will radiate Source is moved to radiation and opens region, and now radiation source sends X ray.When motion sensor does not sense the movement (fortune of capsule It is dynamic), brake homing, radiation source is moved to radiation in the presence of brake and closes region, and now radiation source does not send X Ray.By sensing wriggling of the capsule in big enteral with inductor, control capsule only sends radiation in special time and penetrated Line, patient is reduced by the flux (exposed amount) radiated.
The utility model detects the polyp and protrusion lesion of colon using principle as described above and method, in patient The polyp of colon is often gradually grown up over time, and existing evidence shows, almost all of colon cancer is all originating from knot Intestinal polyp.The utility model is used for the polyp for detecting colon and its hetero-organization distortion, generaI investigation and early stage for colorectal cancer Check.
The ray scanning formula capsule endoscope application method that the utility model is used for Alimentary tract disease examination is as follows:Suffer from before checking Person takes contrast agent, the swallowable capsule scope after contrast agent takes 1-5 hours, when capsule endoscope is in human gastrointestinal tract motion process In, the motion conditions in human colon of the energy sensitive scanning formula of motion sensor 15 capsule endoscope 1, when capsule moves, motion passes The motion that sensor 15 is sensed is converted to electric signal and passes to piezoelectricity micro-displacement brake 20, when piezoelectricity micro-displacement brake 20 when receiving piezoelectric signal, and piezoelectricity micro-displacement brake 20 is in excitation state, the miniature X ray generator 12 on displacement bar 21 from Radiation closes area and is moved to radiation unlatching area, and now ray scanning formula capsule endoscope 1 sends X ray spoke to capsule external environment condition Penetrate, while the radiation detector in capsule senses and records the flux of backward compton scattering, and enumeration data is passed through into indigo plant Tooth communications receive the counting to mobile terminal records instrument 3, the receiving unit 32 of mobile terminal records instrument 3 by Bluetooth communication Data, the processing of single-chip microcomputer 33 data are simultaneously stored in data memory module 34 together with time tag, at the same the data with Time tag is communicated to connect by antenna 35 and cloud server together, and mobile terminal records instrument 3 passes through wireless network and high in the clouds Server communication connects, and is connected between cloud server and data processing terminal 4 by network service, such data processing terminal 4 can download count information data from cloud server automatically, and data processing terminal 4 can be according to the data of download, at software Reason, draws the counting rate and the curve of time of two dimension, and medical personnel differentiate that patient's colon has colon according to the calibration curve information The possibility of polyp or protrusion lesion.Usual this polyp or tissue it is abnormal be probably knot that tumour starts to grow in the gastrointestinal tract Fruit, if physician suspects the polyp occurred or tissue aberrations are probably cancer or pre-cancer, patient needs further knot Enteroscopy confirms.Scan-type capsule endoscope system of the present utility model can be additionally used in generaI investigation and the early detection of colorectal cancer, After data processing terminal 4 receives the data of patient, pass through the analysis of computer software, it would be possible to the trouble of polyp of colon be present Person screens, and notifies patient by risk is assessed, and patient does further enteroscopy according to the assessment information.
The preparation of the surface lubrication coating of embodiment 2
The capsule endoscope case surface of the present invention is additionally provided with slip coating, and the slip coating formula is as follows:
Calculated according to mass percent:Carboxylic propyl methocel 8%, DAAM 30%, polyamide 20%, Unifor 5%, n-butylamine 2%, ethyl acetate 35%.
Preparation method:(1) carboxylic propyl methocel, DAAM, polyamide are placed according to formula rate It is well mixed in container;(2) n-butylamine is added to container;Unifor and ethyl acetate are added to container afterwards In, after homogeneous mixture is formed in container, solution allocation is completed.By the solution spraying configured to capsule shell surface, put Enter baking oven to be heating and curing, 40-80 DEG C of solidification temperature, the hydrophilic of the medical apparatus surface is formed on the medical apparatus surface Coating, thickness are 10-50 μm.
The preparation of the surface lubrication coating of embodiment 3
The capsule endoscope case surface of the present invention is additionally provided with slip coating, and the lubricant coating formula is as follows:
Calculated according to mass percent:Carboxylic propyl methocel 8%, DAAM 30%, polyamide 20%, 1- benzoyl -2- benzene sulfonyl hydrazides 5%, n-butylamine 2%, ethyl acetate 35%.
Preparation method:(1) carboxylic propyl methocel, DAAM, polyamide are placed according to formula rate It is well mixed in container;(2) n-butylamine is added to container;Unifor and ethyl acetate are added to container afterwards In, after homogeneous mixture is formed in container, solution allocation is completed.By the solution spraying configured to capsule shell surface, put Enter baking oven to be heating and curing, 40-80 DEG C of solidification temperature, the hydrophilic of the medical apparatus surface is formed on the medical apparatus surface Coating, thickness are 10-50 μm.
The lubricity of embodiment 4 and fastness test experiments
Lubricant coating is coated on catheter substrate using embodiment 2-3 formula and preparation method.Comparative example 1 is not apply The conduit of coating, comparative example 2 coat lubricant coating prepared by following formula on catheter substrate:Carboxylic propyl methocel 8%, DAAM 50%, unifor 5%, n-butylamine 2%, ethyl acetate 35%.Carry out outside 80 test conduits Frictional force, investigate the fastness and durability test of coating.Frictional force is lower, shows that lubricity is better;Friction is by 50 After secondary friction, frictional force is lower and change is smaller, illustrates that coating abrasion is smaller, that is, coating has preferable fastness. Sample is made after the formulation for coating material used in the present invention is coated on different conduit base materials, and applies normal pressure on sample 400gf, testing friction power, as a result as shown in the table in 37 DEG C of water baths.
Conduit base material Coating First time frictional force (gf) 80th frictional force (gf)
Polyamide Comparative example 1 182.3 More than 300
Polyurethane Comparative example 1 197.5 More than 300
Polyamide Embodiment 2 10.5 11.2
Polyurethane Embodiment 2 11.8 12.0
Polyamide Embodiment 3 13.5 13.9
Polyamide Comparative example 2 60.2 94.1
Polyurethane Comparative example 2 68.4 99.7
The coating made using this method does not show greasy property when being in dry state, and instrumentation etc. will not be produced Influence;After contact with water, water suction forms hydrogel, and water absorption rate is contained due to surface more than 90% and largely plays lubrication Water and give people the sensation of a kind of similar " fish-skin ".The capsule for scribbling above-mentioned coating is forming water-setting into rapid water suction after human body Glue, coefficient of friction between capsule shell and lumen of a body vessel wall surface is set to reduce (approximate can be regarded as the interaction between water and water), Realize increases the effect of lubricity under organizational environment, and accordingly improves it and cross lesion ability.
Due to the combination between the coating and the material surface being modified be not simply by physisorption, and Make to make coating material molecule and substrate molecule form inierpeneirating network structure (i.e. between macromolecular chain and chain by specific process Entanglement spatially), because the force ratio between the entanglement network structure and matrix material is stronger, it is ensured that hydrophilic poly- Compound substrate surface fastness, will not because of friction cause declining to a great extent for greasy property.
Described above is only preferred embodiment of the present utility model, it is noted that for the common skill of the art Art personnel, on the premise of the utility model method is not departed from, some improvement and supplement can also be made, these are improved and supplement Also it should be regarded as the scope of protection of the utility model.

Claims (5)

  1. A kind of 1. capsule endoscope system for gastrointestinal protuberant lesions examination, it is characterised in that the capsule endoscope system Including ray scanning formula capsule endoscope (1), mobile terminal records instrument (3), data processing terminal (4);
    The ray scanning formula capsule endoscope (1) includes capsule-type shell (11), miniature X ray generator (12), radiation detection Device (13), collimator (14), motion sensor (15), battery (16), Bluetooth communication modules (17), radiation proof shield (18), control Circuit (19) processed, piezoelectricity micro-displacement brake (20), displacement bar (21), area (22) are opened in radiation, area (23), radiation are closed in radiation Window (24);Capsule-type shell (11) a diameter of 16-20mm, length 31-35mm;During the radiation proof shield (18) is Empty is spherical, is made up of lead or tungsten material, radiation proof shield (18) shares two, is separately positioned on the upper of capsule-type shell (11) Radiation unlatching area (22) is provided with lower two chambers, in radiation proof shield (18) and area (23) are closed in radiation;It is described to be opened with radiation Centered on opening area (22), along the cross section of ray scanning formula capsule endoscope (1) uniform ring around distribution 4-8 collimator (14), When miniature X ray generator (12), which is in radiation, opens area (22), miniature X ray generator (12) by collimator (14) and Radiation window (24) is to external emission X-ray radiation;The miniature X ray generator (12) shares two, is separately positioned on In lower two radiation proof shields (18), miniature X ray generator (12) is fixed on displacement bar (21);The displacement bar (21) with Piezoelectricity micro-displacement brake (20) connects, when piezoelectricity micro-displacement brake (20) does not receive piezoelectric signal, piezoelectricity micro-displacement system Dynamic device (20) be in stable state, and the miniature X ray generator (12) on displacement bar (21) is corresponding to the spoke in radiation proof shield (18) Penetrate and close area (23), now ray scanning formula capsule endoscope (1) is not to external emission X-ray radiation;When piezoelectricity micro-displacement is braked When device (20) receives piezoelectric signal, piezoelectricity micro-displacement brake (20) is in excitation state, the miniature X ray hair on displacement bar (21) Area (22) are opened in the radiation that raw device (12) corresponds in radiation proof shield (18), and now ray scanning formula capsule endoscope (1) is to glue X-ray radiation is sent outside capsule;
    The motion sensor (15) is arranged in control circuit (19), and motion sensor (15) can sensitive scanning formula capsule endoscope (1) motion conditions in human colon, when capsule moves, the motion that motion sensor (15) is sensed is converted to telecommunications Number pass to piezoelectricity micro-displacement brake (20);Bluetooth communication modules (17) in the ray scanning formula capsule endoscope (1) with Mobile terminal records instrument (3) is connected by Bluetooth communication, and mobile terminal records instrument (3) is led to by wireless network and cloud server Letter connection, is connected between cloud server and data processing terminal (4) by network service;The radiation detector (13) is set Capsule-type shell (11) inner surface and be connected with control circuit (19), radiation detector (13) is carried on the back to the Compton that senses Scattered photon is counted, and count information is transferred into mobile terminal records instrument (3) by Bluetooth communication modules (17), mobile Terminal recorder (3) receives the count information obtained out of ray scanning formula capsule endoscope (1), and by the count information data Pass in cloud server and preserved, data processing terminal (4) downloads count information data from cloud server automatically;
    The mobile terminal records instrument (3) includes power supply (31), receiving unit (32), single-chip microcomputer (33), data memory module (34), antenna (35), controller (36), bandage (37), the power supply (31), receiving unit (32), single-chip microcomputer (33), data are deposited Storage module (34) is linked in sequence, and antenna (35) is connected with single-chip microcomputer (33), and the single-chip microcomputer (33) receives receiving unit (32) Stored after count information data-signal together with time tag in data memory module (34);The receiving unit (32) passes through Bluetooth communication receives the count information data of Bluetooth communication modules (17) transmission, by the processing of single-chip microcomputer (33), by the data With being stored together with time tag in data memory module (34), at the same the data together with time tag by antenna (35) with Cloud server communicates to connect, and is downloaded for data processing terminal (4);The surface of the capsule-type shell (11) is additionally provided with lubrication and applied Layer.
  2. 2. it is used for the capsule endoscope system of gastrointestinal protuberant lesions examination according to claim 1, it is characterised in that described Mobile terminal records instrument (3) has circular housing, institute's power supply (31), receiving unit (32), single-chip microcomputer (33), data memory module (34), antenna (35) is fixed in circular housing.
  3. 3. it is used for the capsule endoscope system of gastrointestinal protuberant lesions examination according to claim 1, it is characterised in that described Data processing terminal (4) is tablet personal computer or mobile phone.
  4. 4. it is used for the capsule endoscope system of gastrointestinal protuberant lesions examination according to claim 1, it is characterised in that described Mobile terminal records instrument (3) is Worn type.
  5. 5. it is used for the capsule endoscope system of gastrointestinal protuberant lesions examination according to claim 1, it is characterised in that described Mobile terminal records instrument (3) is hand-held.
CN201621152904.7U 2016-10-31 2016-10-31 A kind of capsule endoscope system for gastrointestinal protuberant lesions examination Active CN206852604U (en)

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CN201621152904.7U CN206852604U (en) 2016-10-31 2016-10-31 A kind of capsule endoscope system for gastrointestinal protuberant lesions examination

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201621152904.7U CN206852604U (en) 2016-10-31 2016-10-31 A kind of capsule endoscope system for gastrointestinal protuberant lesions examination

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113710154A (en) * 2019-04-18 2021-11-26 消化道官能有限公司 Biosensor capsule and system

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113710154A (en) * 2019-04-18 2021-11-26 消化道官能有限公司 Biosensor capsule and system

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