CN206462965U - A kind of ray scanning formula capsule endoscope system for Alimentary tract disease examination - Google Patents

A kind of ray scanning formula capsule endoscope system for Alimentary tract disease examination Download PDF

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CN206462965U
CN206462965U CN201621152373.1U CN201621152373U CN206462965U CN 206462965 U CN206462965 U CN 206462965U CN 201621152373 U CN201621152373 U CN 201621152373U CN 206462965 U CN206462965 U CN 206462965U
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radiation
capsule endoscope
ray
scanning formula
capsule
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廖专
李兆申
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Second Military Medical University SMMU
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Second Military Medical University SMMU
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Abstract

The utility model is related to a kind of ray scanning formula capsule endoscope system for Alimentary tract disease examination, including ray scanning formula capsule endoscope, mobile terminal records instrument, data processing terminal;The ray scanning formula capsule endoscope includes capsule-type shell, miniature X ray generator, radiation detector, collimator, motion sensor, battery, Bluetooth communication modules, radiation proof shield, control circuit, piezoelectricity micro-displacement brake, displacement bar.Advantage:1st, capsule endoscope system of the present utility model is easy to use, and patient is swallowing capsule, connecting mobile terminal records instrument, can normal activity, after capsule battery exhaust or from anus discharge after data logger is removed, that is, complete check.2nd, ray scanning formula capsule endoscope includes capsule-type shell, miniature X ray generator, radiation detector, can launch x-ray photon in the motion process of capsule in the gastrointestinal tract and be detected, thus efficiently, the carry out Alimentary tract disease examination of quick-speed large-scale.

Description

A kind of ray scanning formula capsule endoscope system for Alimentary tract disease examination
Technical field
The utility model is related to technical field of medical instruments, specifically, is a kind of penetrating for Alimentary tract disease examination Line scan-type capsule endoscope system.
Background technology
Colorectal cancer is commonly called as colorectal cancer, is to occur the cancer in colon.Colon is one section of intestinal tube critically important in human body, its Effect is to absorb the moisture and some other material in the swill digested and assimilated by small intestine, and these residues are finally become Excreted into excrement, and finally.Polyp of colon, is the lesion of colonic mucosal surface protuberance property, generally, is grown in intestinal tube An interior hyperplastic dermopathy, polyp of colon is often gradually grown up over time.Existing evidence shows, almost all of colon cancer All originate from polyp of colon.Therefore the benign polypus for also very little being extractd under colonoscopy is to be capable of one of effective measures of pre- anti-cancer. The prevention emphasis of colorectal cancer essentially consists in increasing generaI investigation and examination dynamics, and generaI investigation can improve colorectal cancer early diagnosis rate, reduce the death rate. At present, the examination for colorectal cancer mainly includes the content of five aspects:1st, medical history is collected;2nd, digital rectal examination;3rd, routine test (blood Conventional, stool OB);4th, CEA is detected;5th, enteroscopy.Enteroscopy is that colonoscopy is followed chamber and is inserted to ileocecus by per anum, from mucous membrane The inspection method of colonic pathological change is observed in side, is the optimal selection of current diagnosis colorectal mucosa lesion.Enteroscopy is by being installed on The electro-photographic of colonoscopy front end is popped one's head in the image transmitting of mucous membrane of colon in electronic computer processing center, after be shown in monitor On screen, the minor variations of colorectal mucosa can be observed.But patient will bear affliction during enteroscopy, and there is the hidden of perforation Suffer from.Although pain when existing Painless can avoid checking, Painless risk is big, there is anesthetic accident and cause dead disease Example happens occasionally.
Capsule endoscope full name is that " intelligent capsule digestive tract endoscope system " is also known as " Medical wireless scope ", in recent years should be For a kind of clinical new-type digestion endoscope, operation principle is that person under inspection passes through oral built-in shooting and signal transmitting apparatus Intelligent capsule, motion and shooting image in alimentary canal are allowed to by alimentary canal creep, and doctor utilizes external image recorder And image workstation, the whole alimentary canal situation of person under inspection is understood, so as to make diagnosis to its state of an illness.Capsule endoscope, which has, to be checked Convenience, hurtless measure, without wire, no pain, without cross-infection, the advantages of do not influence the normal work of patient, extend alimentary canal The visual field of inspection, overcomes poor resistance that traditional plug-in type scope has, is not suitable for oldaged physically weak and the state of an illness is critical Etc. defect.
Chinese patent 2013102959808, discloses a kind of multi-functional capsule endoscope system suitable in alimentary canal, Including capsule endoscope, external work station and Portable magnetic volume array;Described capsule endoscope, external work station and portable Magnet array forms a system by the sensing in magnetic field and the transmission of wireless signal.It can be adjusted according to actual position to be seen It is whole, conveniently, the problem of conventional capsule endoscope is positioned without the legal time safely, effectively is solved, pass through the whole of pH sensor Close, realize the timing pH value detection to privileged site in alimentary canal;Meanwhile, it can be increased using narrow ripple LED light powered lighting arrangement The observation of the strong microstructure pattern to mucomembranous surface, accelerates the difference of the tumour and non-tumour to gastrointestinal system mucomembranous surface Diagnosis.Chinese patent 2005100570398, discloses a kind of intelligent capsule type digestive tract endoscope of three-dimensional imaging, including one To opticator and camera module, each camera module includes imaging sensor, color processor, realtime graphic condensing encoder And interface circuit;Wherein signal will be connected to color processor after signal progress analog-to-digital conversion and carried out at color by imaging sensor Reason, is connected after image compression encoder compresses by UART the or I2C ports of interface circuit with microprocessor, then through microprocessor Device is connected with RF receiving and transmission module, sends information to external by antenna from RF receiving and transmission module, and pass through RF receiving and transmission module Control instruction is received, and connects LED illumination array, images by I/O mouthful after being handled by microprocessor the instruction of receiving The working method and working condition of sensor and RF receiving and transmission module.However, above-mentioned technical proposal uses LED light powered lighting arrangement The shooting image in alimentary canal, but this mode is easily disturbed by colonic contents, it is difficult to it was observed that capped knot , there is viewing blind zone in intestinal polyp, shooting in the gastrointestinal tract has randomness;And after inspection terminates, generally require the doctor of specialty Shield personnel screen to a large amount of photos of shooting and analyzed, time and effort consuming.
The content of the invention
The purpose of this utility model is that there is provided a kind of penetrating for Alimentary tract disease examination for deficiency of the prior art Line scan-type capsule endoscope system.
To achieve the above object, the utility model is adopted the technical scheme that:
A kind of ray scanning formula capsule endoscope system for Alimentary tract disease examination, including ray scanning formula capsule endoscope (1), mobile terminal records instrument (3), data processing terminal (4);
The ray scanning formula capsule endoscope (1) includes capsule-type shell (11), miniature X ray generator (12), radiation Detector (13), collimator (14), motion sensor (15), battery (16), Bluetooth communication modules (17), radiation proof shield (18), control circuit (19), piezoelectricity micro-displacement brake (20), displacement bar (21), radiation open area (22), radiation and close area (23), radiation window (24);The capsule-type shell (11) a diameter of 10mm, 11mm, 12mm, 13mm, 14mm or 15mm, length For 25mm, 26mm, 27mm, 28mm, 29mm, 30mm;The radiation proof shield (18) is hollow spherical, by lead or tungsten material system Into radiation proof shield (18) has two, in the two chambers up and down for being separately positioned on capsule-type shell (11), radiation proof shield (18) area (22) are opened provided with radiation in and area (23) are closed in radiation;It is described by radiate open area (22) centered on, swept along ray Uniform ring is retouched on the cross section of formula capsule endoscope (1) around 4-8 collimator (14) of distribution, when miniature X ray generator (12) place When area (22) are opened in radiation, miniature X ray generator (12) is by collimator (14) and radiation window (24) to external emission X Ray is radiated;The miniature X ray generator (12) has two, be separately positioned on above and below in two radiation proof shields (18), Miniature X ray generator (12) is fixed on displacement bar (21);The displacement bar (21) connects with piezoelectricity micro-displacement brake (20) Connect, when piezoelectricity micro-displacement brake (20) does not receive piezoelectric signal, piezoelectricity micro-displacement brake (20) is in stable state, displacement bar (21) area (23) are closed in the radiation that the miniature X ray generator (12) on corresponds in radiation proof shield (18), and now ray is swept Formula capsule endoscope (1) is retouched not to external emission X-ray radiation;When piezoelectricity micro-displacement brake (20) receives piezoelectric signal, pressure The miniature X ray generator (12) that electric micro-displacement brake (20) is on excitation state, displacement bar (21) is protected corresponding to radiation proof Area (22) are opened in the radiation covered in (18), and now ray scanning formula capsule endoscope (1) outside capsule to sending X-ray radiation;
The motion sensor (15) is arranged on control circuit (19), and motion sensor (15) can sensitive scanning formula capsule Scope (1) motion conditions in human colon, when capsule is moved, the motion that motion sensor (15) is sensed is converted to Electric signal passes to piezoelectricity micro-displacement brake (20);Bluetooth communication modules in the ray scanning formula capsule endoscope (1) (17) it is connected with mobile terminal records instrument (3) by Bluetooth communication, mobile terminal records instrument (3) is taken by wireless network and high in the clouds Business device communication connection, is connected between cloud server and data processing terminal (4) by network service;The radiation detector (13) it is arranged on the inner surface of capsule-type shell (11) and is connected with control circuit (19), radiation detector (13) is to what is sensed Backward compton scattering is counted, and count information is transferred into mobile terminal records instrument by Bluetooth communication modules (17) (3), mobile terminal records instrument (3) receives the count information obtained out of ray scanning formula capsule endoscope (1), and the counting is believed Breath data, which are uploaded in cloud server, to be preserved, and data processing terminal (4) is automatic to download count information from cloud server Data.
Further, the mobile terminal records instrument (3) includes power supply (31), receiving unit (32), single-chip microcomputer (33), data Memory module (34), antenna (35), controller (36), bandage (37), the power supply (31), receiving unit (32), single-chip microcomputer (33), data memory module (34) is linked in sequence, and antenna (35) is connected with single-chip microcomputer (33), and the single-chip microcomputer (33) receives reception Stored after the count information data-signal of unit (32) together with time tag in data memory module (34);It is described to receive single First (32) receive the count information data that Bluetooth communication modules (17) are transmitted by Bluetooth communication, pass through the place of single-chip microcomputer (33) Reason, the data is stored together with time tag in data memory module (34), while the data are led to together with time tag Cross antenna (35) to communicate to connect with cloud server, downloaded for data processing terminal (4).
Further, the mobile terminal records instrument (3) has circular housing, institute's power supply (31), receiving unit (32), monolithic Machine (33), data memory module (34), antenna (35) are fixed in circular housing.
Further, control circuit (19) is fixed in capsule-type shell (11), displacement bar (20), motion sensor (15), Battery (16), Bluetooth communication modules (17), piezoelectricity micro-displacement brake (20) are fixed on control circuit (19).
Further, the data processing terminal (4) is tablet personal computer or mobile phone.
Further, the surface of the capsule-type shell (11) is additionally provided with lubricant coating.
The utility model advantage is:
1st, the ray scanning formula capsule endoscope system of the present utility model for Alimentary tract disease examination is easy to use, patient Swallowing capsule, connecting mobile terminal records instrument, can normal activity, exhausted after capsule battery or from after anus discharge by data Recorder is removed, that is, completes to check.
2nd, ray scanning formula capsule endoscope of the present utility model includes capsule-type shell, miniature X ray generator, radiation spy Device is surveyed, the radiation generator and detector included in capsule are as photon is launched in the motion of capsule in the gastrointestinal tract and carries out Detection, thus efficiently, the carry out Alimentary tract disease examination of quick-speed large-scale.
3rd, the data that the utility model gathers capsule endoscope are transferred to setting mobile terminal records instrument by Bluetooth communication In, further upload and preserved into cloud server, data processing terminal downloads count information from cloud server automatically Data, by software processing, draw the counting rate and the curve of time of two dimension, medical personnel differentiate and suffered from according to the calibration curve information There is the possibility of polyp of colon or protrusion lesion in person's colon.Design of the present utility model reads detection process and result Process is taken to separate, patient is in or the working time can complete to check.
4th, X-ray emitter is arranged to the Open-closure radiation motion structure with motional induction, glue by the utility model Intracapsular including motion sensor, motion sensor is used to induce the capsule motion conditions in enteron aisle, when motion sensor sensing Wriggled to capsule in the big enteral of patient, motion sensor sends signal instruction and gives piezoelectricity micro-displacement brake, piezoelectricity micro-displacement system Dynamic device drive displacement bar movement, and radiation source is moved to radiation unlatching region, now radiation source sends X-ray;Work as kinesthesia Device is answered not sense the movement (motion) of capsule, brake homing, radiation source is moved to spoke in the presence of brake Closing region is penetrated, now radiation source does not send X-ray.Design control capsule only sends radiation in special time and penetrated Line, greatly reduces patient by the time radiated.
5th, capsule-type case surface of the present utility model is additionally provided with lubricant coating, and lubricant coating can water in aqueous environment Change forms water-swellable gel, and the gel is avoided that capsule is directly contacted in enteron aisle in motion process with enteron aisle inwall, significantly The friction between surface both is reduced, the damage to tissue is alleviated.
6th, capsule-type case surface of the present utility model is additionally provided with lubricant coating, and the lubricant coating has good lubrication Property, and adhesive ability is strong, after 80 times are rubbed lubricity do not reduce significantly.
Brief description of the drawings
Accompanying drawing 1 is ray scanning formula capsule endoscope structural representation of the present utility model.
Accompanying drawing 2 is mobile terminal records instrument structural representation of the present utility model.
Accompanying drawing 3 is illustraton of model of the utility model ray scanning formula capsule in colon.
Embodiment
With reference to embodiment, the utility model is expanded on further.It should be understood that these embodiments are merely to illustrate The utility model rather than limitation scope of the present utility model.In addition, it is to be understood that reading in the utility model record After appearance, those skilled in the art can make various changes or modifications to the utility model, and these equivalent form of values equally fall within this Apply for appended claims limited range.
The reference and part being related in accompanying drawing are as follows:
1. ray scanning formula capsule endoscope, 11. capsule-type shells, 12. miniature X ray generators, 13. radiation detectors, 14. collimator, 15. motion sensors, 16. batteries, 17. Bluetooth communication modules, 18. radiation proof shields, 19. control circuits, 20. Area is opened in piezoelectricity micro-displacement brake, 21. displacement bars, 22. radiation, and area, 24. radiation windows, 3. mobile terminals are closed in 23. radiation Recorder, 31. power supplys, 32. receiving units, 33. single-chip microcomputers, 34. data memory modules, 35. antennas, 36. controllers, 37. tie up Band, 4. data processing terminals.
The ray scanning formula capsule endoscope system of the present utility model of embodiment 1
Fig. 1-Fig. 2 is referred to, accompanying drawing 1 is ray scanning formula capsule endoscope structural representation of the present utility model, and accompanying drawing 2 is Mobile terminal records instrument structural representation of the present utility model.The capsule endoscope system include ray scanning formula capsule endoscope 1, Mobile terminal records instrument 3, data processing terminal 4;The ray scanning formula capsule endoscope 1 includes capsule-type shell 11, miniature X and penetrated Line generator 12, radiation detector 13, collimator 14, motion sensor 15, battery 16, Bluetooth communication modules 17, radiation proof shield Cover 18, control circuit 19, piezoelectricity micro-displacement brake 20, displacement bar 21, radiation open area 22, radiation and close area 23, rediation aperture Mouth 24;The a diameter of 10-15mm of the capsule-type shell 11, length is 25-30mm;The radiation proof shield 18 is hollow ball Shape, is made up, radiation proof shield 18 has two of lead or tungsten material, is separately positioned on the two chambers up and down of capsule-type shell 11 It is interior, open area 22 provided with radiation in radiation proof shield 18 and area 23 is closed in radiation;Centered on the area 22 by radiation unlatching, edge is penetrated Uniform ring is around 4-8 collimator 14 of distribution on the cross section of line scan-type capsule endoscope 1, when miniature X ray generator 12 is in When area 22 is opened in radiation, miniature X ray generator 12 is by collimator 14 and radiation window 24 to external emission X-ray radiation; The miniature X ray generator 12 has two, be separately positioned on above and below in two radiation proof shields 18, miniature X ray occurs Device 12 is fixed on displacement bar 21;The displacement bar 21 is connected with piezoelectricity micro-displacement brake 20, when piezoelectricity micro-displacement brake 20 when not receiving piezoelectric signal, and piezoelectricity micro-displacement brake 20 is in 12 pairs of miniature X ray generator on stable state, displacement bar 21 Area 23 should be closed in the radiation in radiation proof shield 18, now ray scanning formula capsule endoscope 1 is not to external emission X-ray spoke Penetrate;When piezoelectricity micro-displacement brake 20 receives piezoelectric signal, piezoelectricity micro-displacement brake 20 is on excitation state, displacement bar 21 The radiation that corresponds in radiation proof shield 18 of miniature X ray generator 12 open area 22, now ray scanning formula capsule endoscope 1 To sending X-ray radiation outside capsule;The motion sensor 15 is arranged on control circuit 19, and motion sensor 15 can sense The motion conditions in human colon of scan-type capsule endoscope 1, when capsule is moved, the motion that motion sensor 15 is sensed Be converted to electric signal and pass to piezoelectricity micro-displacement brake 20;Bluetooth communication modules in the ray scanning formula capsule endoscope 1 17 are connected with mobile terminal records instrument 3 by Bluetooth communication, and mobile terminal records instrument 3 is led to by wireless network and cloud server Letter connection, is connected between cloud server and data processing terminal 4 by network service;The radiation detector 13 is arranged on glue The inner surface of bladder type shell 11 is simultaneously connected with control circuit 19, and 13 pairs of backward compton scatterings sensed of radiation detector enter Row is counted, and count information is transferred into mobile terminal records instrument 3 by Bluetooth communication modules 17, and mobile terminal records instrument 3 connects By the count information obtained out of ray scanning formula capsule endoscope 1, and the count information data are uploaded in cloud server Preserved, data processing terminal 4 is automatic to download count information data from cloud server.
The mobile terminal records instrument 3 includes power supply 31, receiving unit 32, single-chip microcomputer 33, data memory module 34, antenna 35th, controller 36, bandage 37, the power supply 31, receiving unit 32, single-chip microcomputer 33, data memory module 34 are linked in sequence, antenna 35 are connected with single-chip microcomputer 33, and the single-chip microcomputer 33 is received after the count information data-signal of receiving unit 32 together with time tag Store in data memory module 34;The receiving unit 32 receives the counting that Bluetooth communication modules 17 are transmitted by Bluetooth communication Information data, by the processing of single-chip microcomputer 33, the data is stored together with time tag in data memory module 34, simultaneously The data are communicated to connect together with time tag by antenna 35 and cloud server, are downloaded for data processing terminal 4.At data Software processing can be passed through according to the data of download by managing terminal 4, draw the counting rate and the curve of time of two dimension, medical personnel's root According to the calibration curve information, differentiate that patient's colon has the possibility of polyp of colon or protrusion lesion.
Patient takes contrast agent before checking, contrast agent flows through intestines and stomach and discharged together with excreta, and contrast agent is basic It is not absorbed into blood.After contrast agent takes 1-5 hours, patient swallow's ray scanning formula capsule endoscope of the present utility model 1, when capsule is passed through in gastrointestinal tract, the miniature X ray generator radiation X ray in capsule, now intestinal walls, enteron aisle content Thing and contrast agent, enteron aisle outside organization serve as the scattering medium of radiation by Compton scattering, and the photon of scattering passes through enteron aisle Content and contrast agent are returned to be detected by the radiation detector 13 of the inner surface of capsule-type shell 11, is detected within the unit interval The distance of the photon flux of return and radiation detector 13 and colon wall is into inverse relationship.As shown in figure 3, Fig. 3 illustrates glue Capsule is in the model of colon, and due to the presence of contrast agent, the intestinal contents containing contrast agent is difficult to be penetrated by X-ray, therefore works as When capsule is in B location (the corresponding position of polyp of colon), the backward compton scattering counting rate that detector is detected will Higher than the counting rate when capsule is located at location A.Therefore the backward compton scattering counting rate detected according to detector Change with time, can be evaluated whether detector the distance between to colon wall, thus analyze the colonic segment exist polyp of colon or The possibility of protrusion lesion.
The motion sensor 15 can sense the motion conditions for indicating capsule in intestines and stomach, when motion sensor 15 senses Wriggled to capsule in the big enteral of patient, motion sensor 15 sends electric signal and instructed to piezoelectricity micro-displacement brake 20, piezoelectric micromotor Miniature X ray generator 12 is moved to radiation and opens area 22 by displacement brake 20, and now capsule externally sends X-ray.Work as fortune Dynamic sensor 15 does not sense the movement (motion) of capsule, the homing of piezoelectricity micro-displacement brake 20, now miniature X ray Generator 12 is moved to radiation in the presence of motion sensor 15 and closes area 23, and now capsule is not radiated externally.Pass through fortune Sense wriggling of the capsule in big enteral with motion sensor 15, control capsule only sends radiation within the mobile period and penetrated Line, saves power supply, reduces patient by the flux (exposed amount) radiated.
Patient is taken after contrast agent, in specific region the contrast concentration of intestinal contents be it is equally distributed, therefore For single energy photon radiation source, the X-ray-backward compton scattering projected from radiation source returns to radiation detector During, the flux of the backward compton scattering that radiation detector is detected and photon are by the distance of contrast agent into anti- Proportionate relationship.Therefore, when capsule is by enteron aisle position corresponding with polyp of colon, the Compton back of the body that detector is detected Compare what is dramatically increased in scattered light subnumber position adjacent thereto.
Capsule reaches the movement characteristic after large intestine:The continuity that the longitudinal muscle and circular muscle of large intestine are coordinated is shunk, and makes large intestine Some stable intestinal wall contraction waves forward are formed, constantly big intestinal contents are pushed forward.The characteristics of wriggling is that intestinal segment is filled When swollen, longitudinal muscle shrinks first, is shunk followed by circular muscle, material is thus formed diastole in preceding, the posterior peristaltic wave of contraction.It is compacted It is dynamic normal since hepatic flexure of colon, left hemicolon to is pushed intestinal contents with 1~2cm per minute speed.Pushed ahead during colonic peristalsis Strength is very big, is the principal mode that colon is transported.The colonic contents most of the time is motionless, and every a few hours, contraction is opened Begin, colon produces pressure, material is forwardly toward anus extruding.In order that patient is minimized by the radiation of radiation source, spoke The source of penetrating is configured to include motion sensor, motion-sensing in the Open-closure radiation motion structure with motional induction, capsule Device is used to induce the capsule motion conditions in enteron aisle, when motion sensor senses that capsule is wriggled in the big enteral of patient, moves Sensor sends signal instruction and gives piezoelectricity micro-displacement brake, the movement of piezoelectricity micro-displacement brake drive displacement bar, and will radiate Source is moved to radiation and opens region, and now radiation source sends X-ray.When motion sensor does not sense the movement (fortune of capsule It is dynamic), brake homing, radiation source is moved to radiation in the presence of brake and closes region, and now radiation source does not send X Ray.By sensing wriggling of the capsule in big enteral with inductor, control capsule only sends radiation in special time and penetrated Line, reduces patient by the flux (exposed amount) radiated.
The utility model detects the polyp and protrusion lesion of colon using principle as described above and method, in patient The polyp of colon is often gradually grown up over time, and existing evidence shows, almost all of colon cancer is all originating from knot Intestinal polyp.The utility model is used for the polyp for detecting colon and its hetero-organization distortion, generaI investigation and early stage for colorectal cancer Check.
The ray scanning formula capsule endoscope application method that the utility model is used for Alimentary tract disease examination is as follows:Suffer from before checking Person takes contrast agent, the swallowable capsule scope after contrast agent takes 1-5 hours, when capsule endoscope is in human gastrointestinal tract motion process In, the motion conditions in human colon of the energy sensitive scanning formula of motion sensor 15 capsule endoscope 1, when capsule is moved, motion is passed The motion that sensor 15 is sensed is converted to electric signal and passes to piezoelectricity micro-displacement brake 20, when piezoelectricity micro-displacement brake 20 when receiving piezoelectric signal, piezoelectricity micro-displacement brake 20 be in miniature X ray generator 12 on excitation state, displacement bar 21 from Radiation closes area and is moved to radiation unlatching area, and now ray scanning formula capsule endoscope 1 sends X-ray spoke to capsule external environment condition Penetrate, while the radiation detector in capsule senses and records the flux of backward compton scattering, and enumeration data is passed through into indigo plant Tooth communications receive the counting to mobile terminal records instrument 3, the receiving unit 32 of mobile terminal records instrument 3 by Bluetooth communication Data, the processing of single-chip microcomputer 33 data are simultaneously stored in data memory module 34 together with time tag, at the same the data with Time tag is communicated to connect by antenna 35 and cloud server together, and mobile terminal records instrument 3 passes through wireless network and high in the clouds Server communication is connected, and is connected between cloud server and data processing terminal 4 by network service, such data processing terminal 4 automatic can download count information data from cloud server, and data processing terminal 4 can be according to the data of download, at software Reason, draws the counting rate and the curve of time of two dimension, and medical personnel differentiate that patient's colon has colon according to the calibration curve information The possibility of polyp or protrusion lesion.Usual this polyp or tissue it is abnormal be probably knot that tumour starts to grow in the gastrointestinal tract Really, if physician suspects the polyp occurred or tissue aberrations are probably cancer or pre-cancer, patient needs further knot Enteroscopy confirms.Scan-type capsule endoscope system of the present utility model can be additionally used in generaI investigation and the early detection of colorectal cancer, Data processing terminal 4 is received after the data of patient, passes through the analysis of computer software, it would be possible to there is the trouble of polyp of colon Person screens, and notifies patient by risk is assessed, and patient does further enteroscopy according to the assessment information.
The preparation of the surface lubrication coating of embodiment 2
The capsule endoscope case surface of the present invention is additionally provided with slip coating, and the slip coating formula is as follows:
Calculated according to mass percent:Carboxylic propyl methocel 8%, DAAM 30%, polyamide 20%, Unifor 5%, n-butylamine 2%, ethyl acetate 35%.
Preparation method:(1) carboxylic propyl methocel, DAAM, polyamide are placed according to formula rate It is well mixed in container;(2) n-butylamine is added to container;Unifor and ethyl acetate are added to container afterwards In, after homogeneous mixture is formed in container, solution allocation is completed.By the solution spraying configured to capsule shell surface, put Enter baking oven to be heating and curing, 40-80 DEG C of solidification temperature forms the hydrophilic of the medical apparatus surface on the medical apparatus surface Coating, thickness is 10-50 μm.
The preparation of the surface lubrication coating of embodiment 3
The capsule endoscope case surface of the present invention is additionally provided with slip coating, and the lubricant coating formula is as follows:
Calculated according to mass percent:Carboxylic propyl methocel 8%, DAAM 30%, polyamide 20%, 1- benzoyl -2- benzene sulfonyl hydrazides 5%, n-butylamine 2%, ethyl acetate 35%.
Preparation method:(1) carboxylic propyl methocel, DAAM, polyamide are placed according to formula rate It is well mixed in container;(2) n-butylamine is added to container;Unifor and ethyl acetate are added to container afterwards In, after homogeneous mixture is formed in container, solution allocation is completed.By the solution spraying configured to capsule shell surface, put Enter baking oven to be heating and curing, 40-80 DEG C of solidification temperature forms the hydrophilic of the medical apparatus surface on the medical apparatus surface Coating, thickness is 10-50 μm.
The lubricity of embodiment 4 and fastness test experiments
Lubricant coating is coated on catheter substrate using embodiment 2-3 formula and preparation method.Comparative example 1 is not apply The conduit of coating, comparative example 2 coats lubricant coating prepared by following formula on catheter substrate:Carboxylic propyl methocel 8%, DAAM 50%, unifor 5%, n-butylamine 2%, ethyl acetate 35%.Carry out outside 80 test conduits Frictional force, investigate coating fastness and durability test.Frictional force is lower, shows that lubricity is better;Friction is passing through 50 After secondary friction, frictional force is lower and changes smaller, illustrates that coating abrasion is smaller, that is, coating has preferable fastness. Coated on different conduit base materials and sample is made after the formulation for coating material used in the present invention, and apply on sample normal pressure 400gf, testing friction power, as a result as shown in the table in 37 DEG C of water baths.
Conduit base material Coating First time frictional force (gf) 80th frictional force (gf)
Polyamide Comparative example 1 182.3 More than 300
Polyurethane Comparative example 1 197.5 More than 300
Polyamide Embodiment 2 10.5 11.2
Polyurethane Embodiment 2 11.8 12.0
Polyamide Embodiment 3 13.5 13.9
Polyamide Comparative example 2 60.2 94.1
Polyurethane Comparative example 2 68.4 99.7
The coating made using this method does not show greasy property when being in dry state, and instrumentation etc. will not be produced Influence;After contact with water, water suction forms hydrogel, and water absorption rate is contained due to surface more than 90% and largely plays lubrication Water and give people a kind of sensation of similar " fish-skin ".The capsule for scribbling above-mentioned coating is forming water-setting into rapid water suction after human body Glue, makes coefficient of friction between capsule shell and lumen of a body vessel wall surface reduce (interaction that approximate can be regarded as between water and water), The effect of the increase lubricity under organizational environment is realized, and accordingly improves it and crosses lesion ability.
Due to the combination between the coating and the material surface being modified be not simply by physisorption, and Make to make coating material molecule and substrate molecule formation inierpeneirating network structure (i.e. between macromolecular chain and chain by specific process Entanglement spatially), because the force ratio between the entanglement network structure and matrix material is stronger, it is ensured that hydrophilic poly- Compound will not cause declining to a great extent for greasy property in the fastness of substrate surface because of friction.
Described above is only preferred embodiment of the present utility model, it is noted that for the common skill of the art Art personnel, on the premise of the utility model method is not departed from, can also make some improvement and supplement, and these improve and supplemented Also it should be regarded as protection domain of the present utility model.

Claims (7)

1. a kind of ray scanning formula capsule endoscope system for Alimentary tract disease examination, it is characterised in that the capsule endoscope System includes ray scanning formula capsule endoscope (1), mobile terminal records instrument (3), data processing terminal (4);
The ray scanning formula capsule endoscope (1) includes capsule-type shell (11), miniature X ray generator (12), radiation detection Device (13), collimator (14), motion sensor (15), battery (16), Bluetooth communication modules (17), radiation proof shield (18), control Circuit (19) processed, piezoelectricity micro-displacement brake (20), displacement bar (21), radiation open area (22), radiation and close area (23), radiation Window (24);The a diameter of 10-15mm of the capsule-type shell (11), length is 25-30mm;During the radiation proof shield (18) is Empty is spherical, is made up of lead or tungsten material, radiation proof shield (18) has two, is separately positioned on the upper of capsule-type shell (11) In lower two chambers, open area (22) provided with radiation in radiation proof shield (18) and area (23) are closed in radiation;Area is opened to radiate (22) centered on, uniform ring is around 4-8 collimator (14) of distribution along along the cross section of ray scanning formula capsule endoscope (1), when micro- When type X-ray emitter (12) is in radiation unlatching area (22), miniature X ray generator (12) passes through collimator (14) and radiation Window (24) is to external emission X-ray radiation;The miniature X ray generator (12) has two, be separately positioned on above and below two In individual radiation proof shield (18), miniature X ray generator (12) is fixed on displacement bar (21);The displacement bar (21) and piezoelectricity Micro-displacement brake (20) is connected, when piezoelectricity micro-displacement brake (20) does not receive piezoelectric signal, piezoelectricity micro-displacement brake (20) it is in the radiation pass that the miniature X ray generator (12) on stable state, displacement bar (21) corresponds in radiation proof shield (18) Closed zone (23), now ray scanning formula capsule endoscope (1) is not to external emission X-ray radiation;When piezoelectricity micro-displacement brake (20) when receiving piezoelectric signal, the miniature X ray that piezoelectricity micro-displacement brake (20) is on excitation state, displacement bar (21) occurs Area (22) are opened in the radiation that device (12) corresponds in radiation proof shield (18), and now ray scanning formula capsule endoscope (1) is to capsule Outside sends X-ray radiation;
The motion sensor (15) is arranged on control circuit (19), and motion sensor (15) can sensitive scanning formula capsule endoscope (1) motion conditions in human colon, when capsule is moved, the motion that motion sensor (15) is sensed is converted to telecommunications Number pass to piezoelectricity micro-displacement brake (20);Bluetooth communication modules (17) in the ray scanning formula capsule endoscope (1) with Mobile terminal records instrument (3) is connected by Bluetooth communication, and mobile terminal records instrument (3) is led to by wireless network and cloud server Letter connection, is connected between cloud server and data processing terminal (4) by network service;The radiation detector (13) is set Capsule-type shell (11) inner surface and with control circuit (19) be connected, radiation detector (13) to sense Compton the back of the body Scattered photon is counted, and count information is transferred into mobile terminal records instrument (3) by Bluetooth communication modules (17), mobile Terminal recorder (3) receives the count information obtained out of ray scanning formula capsule endoscope (1), and by the count information data Pass in cloud server and preserved, data processing terminal (4) is automatic to download count information data from cloud server.
2. it is used for the ray scanning formula capsule endoscope system of Alimentary tract disease examination according to claim 1, it is characterised in that The mobile terminal records instrument (3) includes power supply (31), receiving unit (32), single-chip microcomputer (33), data memory module (34), day Line (35), controller (36), bandage (37), the power supply (31), receiving unit (32), single-chip microcomputer (33), data memory module (34) it is linked in sequence, antenna (35) is connected with single-chip microcomputer (33), the single-chip microcomputer (33) receives the counting letter of receiving unit (32) Stored after breath data-signal together with time tag in data memory module (34);The receiving unit (32) is logical by bluetooth Letter receives the count information data of Bluetooth communication modules (17) transmission, by the processing of single-chip microcomputer (33), by the data and time Label is stored in data memory module (34) together, while the data are taken together with time tag by antenna (35) and high in the clouds Business device communication connection, is downloaded for data processing terminal (4).
3. it is used for the ray scanning formula capsule endoscope system of Alimentary tract disease examination according to claim 1, it is characterised in that The mobile terminal records instrument (3) has circular housing, institute's power supply (31), receiving unit (32), single-chip microcomputer (33), data storage Module (34), antenna (35) are fixed in circular housing.
4. it is used for the ray scanning formula capsule endoscope system of Alimentary tract disease examination according to claim 1, it is characterised in that The data processing terminal (4) is tablet personal computer or mobile phone.
5. it is used for the ray scanning formula capsule endoscope system of Alimentary tract disease examination according to claim 1, it is characterised in that The mobile terminal records instrument (3) is Worn type.
6. it is used for the ray scanning formula capsule endoscope system of Alimentary tract disease examination according to claim 1, it is characterised in that The mobile terminal records instrument (3) is hand-held.
7. it is used for the ray scanning formula capsule endoscope system of Alimentary tract disease examination according to claim 1, it is characterised in that The surface of the capsule-type shell (11) is additionally provided with lubricant coating.
CN201621152373.1U 2016-10-31 2016-10-31 A kind of ray scanning formula capsule endoscope system for Alimentary tract disease examination Active CN206462965U (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108065903A (en) * 2017-12-28 2018-05-25 青岛大学附属医院 A kind of wireless vibration capsule system for adjusting gastrointestinal motivity
CN110151110A (en) * 2019-06-05 2019-08-23 上海长海医院 Fixable type gastrorrhagia monitors capsule endoscope and gastrorrhagia real-time monitoring system

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108065903A (en) * 2017-12-28 2018-05-25 青岛大学附属医院 A kind of wireless vibration capsule system for adjusting gastrointestinal motivity
CN110151110A (en) * 2019-06-05 2019-08-23 上海长海医院 Fixable type gastrorrhagia monitors capsule endoscope and gastrorrhagia real-time monitoring system
CN110151110B (en) * 2019-06-05 2024-04-23 上海长海医院 Fixable capsule endoscope for monitoring gastrorrhagia and real-time monitoring system for gastrorrhagia

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