CN206573403U - Close strength tester - Google Patents

Close strength tester Download PDF

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Publication number
CN206573403U
CN206573403U CN201621457808.3U CN201621457808U CN206573403U CN 206573403 U CN206573403 U CN 206573403U CN 201621457808 U CN201621457808 U CN 201621457808U CN 206573403 U CN206573403 U CN 206573403U
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CN
China
Prior art keywords
bottle
suction
strength tester
conduit
closing
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CN201621457808.3U
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Chinese (zh)
Inventor
孙雨龙
骆井万
林龙翔
廖妮娜
张珂珂
黄丹
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Shenzhen Institute of Advanced Technology of CAS
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Shenzhen Institute of Advanced Technology of CAS
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Abstract

The utility model embodiment discloses a kind of closing strength tester, the closing strength tester includes aerating device, pressure gauge and bottle,suction, the manometric blow vent is connected with the inflation inlet of the aerating device and the branch pipe of the bottle,suction, the air inlet for the container that the bottleneck of the bottle,suction is formed with test serum is connected, and aperture is provided with the container of the test serum formation.Using the utility model, the accuracy of the performance test of closing intensity can be improved.

Description

Close strength tester
Technical field
The utility model is related to pharmaceutical technology field, more particularly to a kind of closing strength tester.
Background technology
With the research and development of tissue adhesive, Wound care market, especially sealer and styptic are quick to increase It is long.Clinically, according to the position of traumatic wounds, size, the size of amount of bleeding, different hemostasia products can be used, at present Occur in that various hemostatic materials.Accordingly, it would be desirable to which the various performances to various hemostatic materials are evaluated, for example, hemostasis Speed, Adhesion property, closing intensity etc..
In the prior art, the mechanical property for hemostatic material is as mostly excessively coarse and do not have in closed the evaluation in intensity There is systematicness, cause that its index can not accurately be tested.It should be noted that hemostatic material is fallen within for closing aperture or hole One kind of the encapsulant of gap, when considering the anthemorrhagic performance of hemostatic material, it is also desirable to consider whether hemostatic material can be to tissue The effect of hemostasis and closing is played in bleeding and infiltration.Study and find through inventor, because hemostatic material is applied to haemostatic state When lower, the closing intensity, it is necessary to certain is influenceed by blood pressure, can just effectively achieve to tissue bleeding and penetrate into whereabouts blood Hemostatic material, which systematic can not be simulated, with the test mode of the effect of closing, therefore existing hemostatic material is applied to human body The situation of bleeding state, it is impossible to the closed performance of objective appraisal hemostatic material.
That is, the test on the closed performance of the encapsulant for closing aperture or hole is deposited in the prior art The problem of test result accuracy is not enough.
Utility model content
Based on this, deposited to solve the test in conventional art for the closed performance for the encapsulant for closing aperture or hole Test result the not enough technical problem of accuracy, spy proposes a kind of closing strength tester.
One kind closing strength tester, the closing strength tester includes aerating device, pressure gauge and bottle,suction, described Manometric blow vent is connected with the inflation inlet of the aerating device and the branch pipe of the bottle,suction, the bottleneck of the bottle,suction It is connected with the air inlet of the container of test serum formation, aperture is provided with the container of the test serum formation.
Optionally, in one of the embodiments, the aerating device is aerated capsule ball.
Optionally, in one of the embodiments, the first end connection of the manometric blow vent and three-way pipe, described The inflation inlet of aerating device is connected with the second end of the three-way pipe, the 3rd end of the branch pipe of the bottle,suction and the three-way pipe It is connected.
Optionally, in one of the embodiments, the inflation inlet of the aerating device passes through the first conduit and the threeway Second end of the pipe branch pipe of the bottle,suction that is connected is connected with the 3rd end of the three-way pipe by the second conduit, the bottle,suction The air inlet of container that is formed by the 3rd conduit with test serum of bottleneck be connected.
Optionally, in one of the embodiments, collapsible bag is provided between the aerating device and the pressure gauge, institute Stating collapsible bag includes the first blow vent and the second blow vent, the first ventilation of the inflation inlet of the aerating device and the collapsible bag Mouth is connected by the 4th conduit, and the second end of the three-way pipe is connected with the second blow vent of the collapsible bag by the 5th conduit Connect.
Optionally, in one of the embodiments, the bottle mouth position of the bottle,suction is provided with rubber stopper with holes, the suction filtration The bottle,suction is inserted in perforate of the bottle with one end of the 3rd conduit on the rubber stopper, described in the 3rd conduit insertion One end of bottle,suction is located at the top for the liquid being equipped with the bottle,suction.
Optionally, in one of the embodiments, the volume of the bottle,suction is 1000ml, is equipped with the bottle,suction Liquid is 250ml deionized waters.
Optionally, in one of the embodiments, the bottle,suction is cone.
Optionally, in one of the embodiments, the closing strength tester also includes rack for test tube, and the pressure gauge is consolidated It is scheduled on the rack for test tube.
Optionally, in one of the embodiments, first conduit, second conduit and the 3rd conduit are Perspex conduit.
The closing strength tester evaluation that the above-mentioned closing strength tester of the utility model offer is different from the past is stopped blooding The scheme of the anthemorrhagic performance of material, the mode of blood pressure is replaced using air pressure, the mode of the bleeding of people's in-vivo tissue and seepage is simulated, More simulate hemostatic material really hemostasis scene in human blood-pressure for the closing intensity of hemostatic material influence, raising It is used for the accuracy for closing the test of the closing intensity of the encapsulant of aperture or hole in test.
That is, during testing the closing intensity of the encapsulant for closing aperture or hole, Set on the container for test serum (such as animal tissue) formation that hemostatic material to be measured is applied to simulation human body blood outlet Aperture on, after gel layer to be formed, be constantly inflated to increase the air pressure inside test serum by aerating device So that the gel layer of hemostatic material formation to be measured is by bursting, so as to obtain the maximum pressure that hemostatic material to be measured can bear Value, i.e., the maximum closing intensity that hemostatic material to be measured can bear.That is, replacing the mode of blood pressure, mould using air pressure Intended the mode of the bleeding of people's in-vivo tissue and seepage, rebuild hemostatic material really hemostasis scene in human blood-pressure for The influence of the closing intensity of hemostatic material, improves and is testing the closing intensity for the encapsulant for being used to close aperture or hole The accuracy of test.
Brief description of the drawings
, below will be to embodiment in order to illustrate more clearly of the utility model embodiment or technical scheme of the prior art Or the accompanying drawing used required in description of the prior art is briefly described, it should be apparent that, drawings in the following description are only It is some embodiments of the present utility model, for those of ordinary skill in the art, is not paying the premise of creative work Under, other accompanying drawings can also be obtained according to these accompanying drawings.
Wherein:
Fig. 1 is a kind of structural representation for closing strength tester in one embodiment;
Fig. 2 is a kind of structural representation for closing strength tester in another embodiment.
Embodiment
Below in conjunction with the accompanying drawing in the utility model embodiment, the technical scheme in the utility model embodiment is carried out Clearly and completely describe, it is clear that described embodiment is only a part of embodiment of the utility model, rather than whole Embodiment.Based on the embodiment in the utility model, those of ordinary skill in the art are not under the premise of creative work is made The every other embodiment obtained, belongs to the scope of the utility model protection.
To solve to be used in conventional art the survey that the test for the closed performance for closing the encapsulant of aperture or hole is present The not enough technical problem of the accuracy of test result, in the present embodiment, spy propose a kind of closing strength tester.
With reference to Fig. 1, Fig. 1 illustrates a kind of structural representation for closing strength tester.
Specifically, in Fig. 1, closing strength tester includes aerating device 10, pressure gauge 20 and bottle,suction 30, described The blow vent 201 of pressure gauge 20 is connected with the inflation inlet 101 of the aerating device 10 and the branch pipe 301 of the bottle,suction 30, The air inlet 401 for the container 40 that the bottleneck 302 of the bottle,suction 30 is formed with test serum is connected, and the test serum is formed Container 40 on be provided with aperture 402.
Specifically, aerating device can be aerated capsule ball, can by press or 10 come pairs of extruding aerated capsule ball with The object that aerated capsule asks 10 inflation inlet 101 to connect is inflated, that is to say, that pressing or extruding aerated capsule ball 10 When, gas can be entered from the inflation inlet 101 of aerated capsule ball with the object that inflation inlet 101 is connected.
Further, in the present embodiment, the connection between pressure gauge 20 and aerating device 10 and bottle,suction 30 can be with Connected by three-way pipe, i.e., the blow vent 201 of pressure gauge 20 is connected with the first end 211 of three-way pipe 21, aerating device 10 Inflation inlet 101 be connected with the second end 212 of three-way pipe 21;The branch pipe 301 of bottle,suction 30 connects with the 3rd end 213 of three-way pipe 21 Connect.
Further, pressure gauge 20, aerating device 10 and three-way pipe 21, bottle,suction 30, the container of test serum formation It can be connected between 40 by conduit, the inflation inlet 101 of test serum 10 passes through the first conduit 1001 and the second of three-way pipe 21 End 212 is connected;The branch pipe 301 of bottle,suction 30 is connected with the 3rd end 213 of three-way pipe 21 by the second conduit 1002, bottle,suction 30 The air inlet 401 of container 40 that is formed by the 3rd conduit 1003 with test serum of bottleneck 302 be connected.
It should be noted that in the present embodiment, pressure gauge 20 can be intelligent digital pressure gauge or other shapes Air pressure in the pressure gauge of formula, the space that can be connected for test with the blow vent 201 of pressure gauge 20, and in pressure gauge 20 Reading on show the occurrence of measured air pressure.
The container 40 of above-mentioned test serum formation can also be able to be cystic container for tubular container, for example, it may be dog The animal tubular tissues such as small intestine, animals iv blood vessel or animal artery blood vessel, also, one end 401 of the animal tubular tissue The 3rd conduit 1003 is connected, and first end is clamped with Medical hemostatic clamp, to ensure the air-tightness inside hemostasis tester.Another In individual embodiment, the container 40 of above-mentioned test serum formation can also be the animal bourse of such as gall-bladder.The animal cryptomere The opening (being the air inlet 401 of the container 40 of test serum formation) of tissue is connected with the 3rd conduit 1003.Need explanation Be, in other embodiments, the container 40 of above-mentioned test serum formation can also be other it is abiotic organize the formation of it is container-like Tissue, be not limited in the utility model.
Further, the aperture 402 that sets is to imitate actual bleeding on the container 40 of above-mentioned test serum formation Real scene during with seepage, for example, the pore size in the aperture 402 is syringe pillow size;It should be noted that at this In embodiment, the pore size in the aperture 402 to being set on the container 40 of above-mentioned test serum formation is not limited, and is only needed Detected materials formation gel can be caused when smearing detected materials or smear layer is formed.
It should be noted that in the present embodiment, the container 40 of above-mentioned test serum formation also can also be its hetero-organization, And it is not only the container for being limited to test serum formation, that is to say, that strength tester is closed in the present embodiment can also also use In the aperture in non-test serum or the test of the closed performance of the encapsulant of hole.
It should be noted that in the present embodiment, above-mentioned conduit or three-way pipe are transparent plastic conduit, also, envelope It is sealed for closing inside the whole equipment of strength tester, that is to say, that needed during the closing strength tester is used Ensure the overall air-tightness of closing strength tester.
Further, in the present embodiment, as depicted in figs. 1 and 2, it is provided with band at the bottleneck 302 of above-mentioned bottle,suction 30 Suction filtration is inserted in hole rubber stopper 303, the perforate 3031 of one end 10031 of the conduit 1003 of bottle,suction 30 and the 3rd on rubber stopper 303 Bottle 30, one end 10031 of the 3rd conduit 1003 insertion bottle,suction 30 is located at the top for the liquid being equipped with bottle,suction 30.
That is, the bottleneck 302 of bottle,suction is sealed by rubber stopper 303 with holes, and bottle,suction 30 is by inserting The 3rd conduit 1003 for entering rubber stopper 303 with holes is connected with the container 40 that test serum is formed.
Optionally, in the present embodiment, the volume of above-mentioned bottle,suction 30 is 1000ml, and the liquid being equipped with bottle,suction 30 is 250ml deionized waters;Further, the shape of bottle,suction 30 can be cone.
In the present embodiment, bottle,suction 30 can play cushioning effect to the gas in closing strength tester, to cause envelope Close the gas in strength tester it is gentle uniformly full of inside whole tester so that the pressure that pressure gauge 20 is measured Value is consistent with the pressure value in the container 40 of test serum formation, so that being set on the container 40 of test serum formation When the coating that the detected materials smeared on the aperture 402 put are formed is by bursting, its close intensity corresponding to occurrence with The pressure value that pressure gauge 20 is measured is consistent, so as to improve the accuracy of test.
Further, as shown in Fig. 2 in the closing strength tester that Fig. 2 is shown, aerating device 10 and pressure gauge It is provided with collapsible bag 50 between 20, collapsible bag 50 includes the first blow vent 501 and the second blow vent 502, aerating device 10 fills Gas port 101 is connected with the first blow vent 501 of collapsible bag 50 by the 4th conduit 1004, the second end 212 of three-way pipe 21 and glue Second blow vent 502 of pouch 50 is connected by the 5th conduit 1005.
That is, when being inflated inside 10 pairs of closing strength testers of aerating device, gas first is charged into capsule Inside bag 50, then enter back into other devices, directly tester inside is inflated so as to avoid, in tester The flowing of the gas in portion plays cushioning effect, so that being smeared on the aperture 402 set on the container 40 of test serum formation The coating that is formed of detected materials by bursting when, it closes the pressure that the occurrence corresponding to intensity is measured with pressure gauge 20 Value is consistent, so as to improve the accuracy of test.
In order that the convenience of used time, in the present embodiment, above-mentioned closing strength tester also include rack for test tube 60, pressure gauge 20 are fixed on rack for test tube 60, so as to facilitate user to be more convenient during being tested using above-mentioned closing strength tester Reading pressure gauge 20 reading.
Specifically, following application method and operating method to above-mentioned closing strength tester, using encapsulant as hemostasis Illustrated exemplified by material.
Following steps S102-106 can be specifically divided into:
Step S102:Detected materials are applied on the aperture set on the container of the test serum formation, wait pre- If duration makes its gel, the application area of the detected materials is more than the area in the aperture.
It should be noted that in the present embodiment, detected materials are the encapsulant available for closing aperture or hole, such as Hemostatic material of painting type etc..In the following description, so that encapsulant is hemostatic material as an example, to the specific mistake of the above method Journey is illustrated.
When being tested using foregoing closing strength tester the closing intensity of hemostatic material, by such as water to be measured The hemostatic material of gel is applied on the aperture 402 set on the container 40 of foregoing test serum formation, also, the hemostasis smeared The application area of material is more than the area in aperture 402, so that the hemostatic material smeared can cover aperture 402.
It should be noted that in the present embodiment, to be measured available for above-mentioned tester can be used for closing aperture or hole The encapsulant of gap be limited to can painting type encapsulant or the encapsulant of adhesive formula, for example, hydrogel material only Blood material etc..In the present embodiment, hemostatic material is not limited, it is only necessary to which the hemostatic material adheres to above-mentioned simulation and moved On property management shape or bourse, and the aperture in animal tubulose or bourse can be sealed.
In the present embodiment, it is not to smear the container 40 that hemostatic material or cohesive stanch bleeding material are formed in test serum It aerating device 10 can be used to be inflated after on the aperture 402 of upper setting, and need smearing hemostatic material or stickup The regular hour is waited after hemostatic material, so that the adhesion that hemostatic material forms firm gel layer or hemostatic material is steady Gu, with the accuracy for the performance test for ensureing hemostatic material;For example, the duration waited can be preset duration 15 minutes.
Step S104:It is inflated by the aerating device, until the gel layer rupture of detected materials formation.
In the present embodiment, by closing strength tester inside be inflated with change the air pressure inside tester come Influence in hemostasis of the blood in human body in pressure for hemostatic material is simulated, i.e., by constantly pressing or extruding aerating device 10 Tester inside is inflated, to increase the air pressure inside tester.
It should be noted that in the present embodiment, the frequency being inflated by the aerating device is no more than the pressure The numerical value jumping frequency rate of power table, for example, the frequency of pressing aerated capsule ball is no more than the manometric numerical value jumping frequency rate.Pressure The numerical value jumping frequency rate of power table is manometric sensitivity, if pressing test serum frequency exceeded it is manometric sensitive Degree, that is, inflate too fast, then when being likely to result in the gel layer of detected materials formation by bursting, the pressure value shown on pressure gauge is also stopped Stay in the pressure value that previous instant is measured, i.e., be not detected materials formation gel layer by pressure value during bursting, so as to cause Test result is inaccurate.
Step S106:The manometric pressure value is recorded as the closing intensity level of the detected materials.
Manometric pressure value is the gel layer for forming detected materials when the gel layer of detected materials formation is by bursting Closing intensity occurrence, the maximum closing intensity that as detected materials can be born during hemostasis.
Optionally, in the present embodiment, temperature may influence the anthemorrhagic performance of hemostatic material, therefore, in the present embodiment In, in order to more accurately simulate anthemorrhagic performance of the hemostatic material in real hemostasis, in addition it is also necessary to which test serum is formed Container 40 and tester are generally held in body temperature.
Specifically, methods described also includes:The closing strength tester is placed in water-bath, to keep the envelope Strength tester is closed in preset temperature, for example, preset temperature is 37 degree.
It should be noted that in the present embodiment, closing strength tester integrally can be prevented from water-bath protecting Default temperature is held, or, can also be that bottle,suction is placed in water-bath, the then liquid by being equipped with bottle,suction The temperature inside tester to be adjusted.
The closing strength tester evaluation that the above-mentioned closing strength tester of the utility model offer is different from the past is stopped blooding The scheme of the anthemorrhagic performance of material, the mode of blood pressure is replaced using air pressure, the mode of the bleeding of people's in-vivo tissue and seepage is simulated, More simulate hemostatic material really hemostasis scene in human blood-pressure for the closing intensity of hemostatic material influence, raising It is used for the accuracy for closing the test of the closing intensity of the encapsulant of aperture or hole in test.
That is, during testing the closing intensity of the encapsulant for closing aperture or hole, Set on the container for test serum (such as animal tissue) formation that hemostatic material to be measured is applied to simulation human body blood outlet Aperture on, after gel layer to be formed, be constantly inflated to increase the air pressure inside test serum by aerating device So that the gel layer of hemostatic material formation to be measured is by bursting, so as to obtain the maximum pressure that hemostatic material to be measured can bear Value, i.e., the maximum closing intensity that hemostatic material to be measured can bear.That is, replacing the mode of blood pressure, mould using air pressure Intended the mode of the bleeding of people's in-vivo tissue and seepage, rebuild hemostatic material really hemostasis scene in human blood-pressure for The influence of the closing intensity of hemostatic material, improves and is testing the closing intensity for the encapsulant for being used to close aperture or hole The accuracy of test.
Above disclosed is only the utility model preferred embodiment, can not limit the utility model with this certainly Interest field, therefore equivalent variations made according to the utility model claim still belong to the scope that the utility model is covered.

Claims (10)

1. one kind closing strength tester, it is characterised in that the closing strength tester includes aerating device, pressure gauge and taken out Filter flask, the manometric blow vent is connected with the inflation inlet of the aerating device and the branch pipe of the bottle,suction, described to take out The air inlet for the container that the bottleneck of filter flask is formed with test serum is connected, and hole is provided with the container of the test serum formation Footpath.
2. closing strength tester according to claim 1, it is characterised in that the aerating device is aerated capsule ball.
3. closing strength tester according to claim 1, it is characterised in that the manometric blow vent and three-way pipe First end connection, the inflation inlet of the aerating device is connected with the second end of the three-way pipe, the branch pipe of the bottle,suction and 3rd end of the three-way pipe is connected.
4. closing strength tester according to claim 3, it is characterised in that the inflation inlet of the aerating device passes through One conduit is connected with the second end of the three-way pipe, and the 3rd end of the branch pipe of the bottle,suction and the three-way pipe is led by second Pipe is connected, and the air inlet for the container that the bottleneck of the bottle,suction is formed by the 3rd conduit with test serum is connected.
5. closing strength tester according to claim 3, it is characterised in that the aerating device and the pressure gauge it Between be provided with collapsible bag, the collapsible bag includes the first blow vent and the second blow vent, the inflation inlet of the aerating device and institute The first blow vent for stating collapsible bag is connected by the 4th conduit, the second end of the three-way pipe and the second ventilation of the collapsible bag Mouth passes through the 5th conduit and connected.
6. closing strength tester according to claim 4, it is characterised in that the bottle mouth position of the bottle,suction is provided with band The bottle,suction, institute are inserted in perforate of the one end of hole rubber stopper, the bottle,suction and the 3rd conduit on the rubber stopper The one end for stating the 3rd conduit insertion bottle,suction is located at the top for the liquid being equipped with the bottle,suction.
7. closing strength tester according to claim 6, it is characterised in that the volume of the bottle,suction is 1000ml, The liquid being equipped with the bottle,suction is 250ml deionized waters.
8. closing strength tester according to claim 1, it is characterised in that the bottle,suction is cone.
9. closing strength tester according to claim 1, it is characterised in that the closing strength tester also includes examination Pipe support, the pressure gauge is fixed on the rack for test tube.
10. closing strength tester according to claim 4, it is characterised in that first conduit, second conduit And the 3rd conduit is perspex conduit.
CN201621457808.3U 2016-12-28 2016-12-28 Close strength tester Active CN206573403U (en)

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Application Number Priority Date Filing Date Title
CN201621457808.3U CN206573403U (en) 2016-12-28 2016-12-28 Close strength tester

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Application Number Priority Date Filing Date Title
CN201621457808.3U CN206573403U (en) 2016-12-28 2016-12-28 Close strength tester

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108254256A (en) * 2016-12-28 2018-07-06 中国科学院深圳先进技术研究院 Close strength tester and closing strength test method
CN109855976A (en) * 2017-11-30 2019-06-07 北京航空航天大学 A kind of Diffusion Bonded Joint tensile strength detection method

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108254256A (en) * 2016-12-28 2018-07-06 中国科学院深圳先进技术研究院 Close strength tester and closing strength test method
CN109855976A (en) * 2017-11-30 2019-06-07 北京航空航天大学 A kind of Diffusion Bonded Joint tensile strength detection method

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