CN206529484U - Cell culture operations integral system - Google Patents
Cell culture operations integral system Download PDFInfo
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- CN206529484U CN206529484U CN201621486542.5U CN201621486542U CN206529484U CN 206529484 U CN206529484 U CN 206529484U CN 201621486542 U CN201621486542 U CN 201621486542U CN 206529484 U CN206529484 U CN 206529484U
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- cell culture
- gas
- integral system
- culture operations
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Abstract
The utility model provides a kind of cell culture operations integral system, and the cell culture operations integral system includes housing, and the front side of the housing has operation gloves；The housing is internal layer, the double-decker of outer layer composition, and the upper wall and lower wall of the internal layer have through hole；The outer layer has gas feed, gas vent and humidification port；The cell culture operations integral system further comprises：Heating module, the heating module is arranged in the interlayer；Conveyor module, the conveyor module conveys gas so that gas has the advantages that gas consumption is small in internal layer, interlayer internal circulation flow the utility model.
Description
Technical field
The utility model is related to cell culture, more particularly to cell culture operations integral system.
Background technology
Cell culture is needed in a suitable environment, such as suitable gas concentration, suitable cleanliness factor, suitable temperature
Degree and suitable humidity (being usually saturated humidity or high humility), so as to ensure cell safety, normal growth.
At present, cell culture is mainly carried out by cell culture incubator on the market, and cell manipulation is mainly in clean bench or life
Carried out in thing safety cabinet, to prevent pollution.The main deficiency of this kind of cell culture incubator is：
1. cell culture and operation are separated, the pollution in transmittance process is caused；
2. the clean bench or Biohazard Safety Equipment of cell manipulation are without gas concentration control and temperature control, it is impossible to ensure thin
The uniformity of born of the same parents' culture environment, influences the normal growth of cell；
3. under high humidity environment, there is condensed water in the inner surface of cell culture incubator, and pollution risk is big.
Utility model content
To solve the deficiency in above-mentioned prior art, the utility model provides that a kind of pollution risk is small, gas disappears
The cell culture operations integral system that consumption is small, gas concentration control efficiency is high.
The purpose of this utility model is achieved through the following technical solutions：
A kind of cell culture operations integral system, the cell culture operations integral system includes housing, the shell
The front side of body has operation gloves；
The housing is internal layer, the double-decker of outer layer composition, and the upper wall and lower wall of the internal layer have through hole；It is described outer
Layer has gas feed, gas vent and humidification port；
The cell culture operations integral system further comprises：
Heating module, the heating module is arranged in the interlayer of the double-decker formation；
Conveyor module, the conveyor module conveys gas so that gas is in internal layer, interlayer internal circulation flow.
Compared with prior art, the utility model have the advantage that for：
1. the hot gas set protection interlayer of internal layer periphery, the temperature in the gas inside internal layer, interlayer is heated by air circulation
Degree is higher than inside internal layer, effectively prevents internal layer inwall from condensed water occur, reduces contaminated risk；
2. cell culture operations are integrated, the culture amount of cell is effectively increased；
3. reducing the loss of the gas in the control of internal layer target gas levels, the efficiency of gas concentration control is accelerated.
Brief description of the drawings
Referring to the drawings, disclosure of the present utility model will be easier to understand.Skilled addressee readily understands that
It is：These accompanying drawings are used only for illustrating the technical solution of the utility model, and are not intended to protection of the present utility model
Scope is construed as limiting.In figure：
Fig. 1 is the structure diagram of the cell culture operations integral system according to the utility model embodiment 1.
Embodiment
Fig. 1 and following description describe optional embodiment of the present utility model to instruct those skilled in the art how real
Apply and reproduce the utility model.In order to instruct technical solutions of the utility model, simplify or eliminate some conventional aspects.Ability
Field technique personnel should be appreciated that modification or replacement from these embodiments will be in the range of the utility model.This area skill
Art personnel should be appreciated that following characteristics can combine to form multiple modifications of the present utility model in a variety of ways.Thus, this reality
Following optional embodiments are not limited to new, and are only limited by claim and their equivalent.
Embodiment 1：
Fig. 1 schematically illustrates the structure diagram of the cell culture operations integral system of the utility model embodiment,
As shown in figure 1, the cell culture operations integral system includes：
Housing, the housing has gas access, gas vent and humidification port, and the double-deck knot constituted for internal layer, outer layer
Structure；The upper wall and lower wall of the internal layer have through hole；The front side of housing has operation gloves；
Conveyor module, such as blower fan, the conveyor module are arranged on the through hole of the upper wall of the internal layer or the downside of through hole,
For the gas in the internal layer to be transported into regulation device so that gas is in internal layer, interlayer internal circulation flow；
Heating module, the flake heater, the heating module is arranged in the interlayer, such as the inwall of outer layer, side
Portion's interlayer, top interlayer, bottom interlayer have heating module, wherein the heating module in the interlayer of front side is transparent, are easy to see
Internal layer is examined, while improving heating uniformity；
Filter, the filter is arranged on the bottom of the conveyor module, the projection of the filter in the horizontal plane
The figure surrounded with the inwall of the internal layer on the horizontal plane is overlapped；
Regulation device, the regulation device is respectively at the storage of object gas, release according to the difference of running parameter
State, the regulation device is arranged in the top interlayer；The regulation device is 2, is oxygen molecule sieve, carbon dioxide
Molecular sieve, carries out adsorption and desorption, so as to store, discharge object gas using pressure swing adsorption (PSA) to gas molecule；
Oxygen in the internal layer measured, the content of carbon dioxide are sent to processor by sensor, the sensor；
Processor, the processor controls the working condition of the regulation device according to the content received：If less than mesh
Scale value, makes regulation device be in release conditions by control；If higher than desired value, making regulation device be in storage shape by control
State.
The method of work of the cell culture operations integral system of the utility model embodiment, the cell culture operations one
The method of work of body system comprises the following steps：
(A1) under conveyor module work, gas is in internal layer to lower flowing；
(A2) gas of interlayer is entered in bottom interlayer, sidepiece interlayer, top interlayer by the through hole of the internal layer lower wall
Interior flowing, and it is heated module heating；
The inwall of the internal layer does not have condensed water；
(A3) gas enters in internal layer from the through hole of the internal layer upper wall；
The control method of target gas content comprises the following steps in internal layer：
(B1) the target gas such as oxygen, carbon dioxide in gas sensor detection cell culture operations integral system internal layer
The content of body, and it is sent to processor；
(B2) processor goes to control the working condition of regulation device according to the content received：
If desired for the content of reduction object gas, into step (B3)；
If desired for the content of rise object gas, into step (B4)；
As that need not adjust, into step (B5)；
(B3) parameter of the regulation device is controlled, regulation device is in object gas storing state；In conveyor module
In the presence of, gas enters in interlayer from the lower wall of internal layer, is flowed up to along the interlayer between the wall of side in the interlayer between upper wall,
Object gas in gas is adjusted device storage, finally enters from the upper wall of internal layer inside internal layer；Into step (B1)；
(B4) parameter of the regulation device is controlled, object gas release conditions are in using regulation device；In conveying mould
In the presence of block, gas enters in interlayer from the lower wall of internal layer, the interlayer flowed up to along the interlayer between the wall of side between upper wall
Interior, the object gas of regulation device storage is discharged into gas, is finally entered from the upper wall of internal layer inside internal layer；Into step
(B1)；
(B5) terminate；
In above process, if by circulating several times, the target gas content in internal layer still can not reach target
Value, then need to inject foreign gas into the housing by the gas access on housing：As target gas content is all the time in housing
Less than desired value, then inject target gas content and be higher than the gas of desired value, so as to reduce in housing object gas in gas
Content；Target gas content is consistently higher than desired value in such as housing, then injects the gas that target gas content is less than desired value, from
And reduce the content of object gas in gas in housing.
Embodiment 2：
The cell culture operations integral system of the utility model embodiment, as different from Example 1：
1. regulation device is arranged on the outside of the housing, input and output end are respectively communicated with the double-decker of housing
Interlayer between the wall of side；
2. being additionally provided with conveyor module, the gas of interlayer is transported to the regulation device.
Claims (8)
1. a kind of cell culture operations integral system, the cell culture operations integral system includes housing, the housing
Front side have operation gloves；It is characterized in that：
The housing is internal layer, the double-decker of outer layer composition, and the upper wall and lower wall of the internal layer have through hole；The outer layer tool
There are gas feed, gas vent and humidification port；
The cell culture operations integral system further comprises：
Heating module, the heating module is arranged in the interlayer of the double-decker formation；
Conveyor module, the conveyor module conveys gas so that gas is in internal layer, interlayer internal circulation flow.
2. cell culture operations integral system according to claim 1, it is characterised in that：The heating module is sheet
Heater element, is arranged on the inwall of the outer layer；It is transparent to be arranged on the heating module of the inwall of front side outer layer.
3. cell culture operations integral system according to claim 1, it is characterised in that：The heating module is arranged on
On the inwall of the upside of the outer layer, downside and all sidepieces.
4. cell culture operations integral system according to claim 1, it is characterised in that：The cell culture operations one
Body system further comprises：
Filter, the filter is arranged on the downside of the internal layer upper wall, filter projection in the horizontal plane and institute
State the figure coincidence that the inwall of internal layer is surrounded on the horizontal plane.
5. cell culture operations integral system according to claim 1, it is characterised in that：The cell culture operations one
Body system further comprises：
Regulation device, the regulation device is respectively at the storage of object gas, release conditions according to the difference of running parameter,
The output end of the regulation device connects the interlayer；
The content of object gas in the housing measured is sent to processor by sensor, the sensor；
Processor, the processor controls the working condition of the regulation device according to the content received.
6. cell culture operations integral system according to claim 5, it is characterised in that：The regulation device is arranged on
In the interlayer, conveyor module is arranged on the downside of the through hole of the upper wall of the internal layer.
7. cell culture operations integral system according to claim 5, it is characterised in that：The regulation device is arranged on
The outside of the housing.
8. cell culture operations integral system according to claim 5, it is characterised in that：The object gas is oxygen
Gas, carbon dioxide, the regulation device are molecular sieve.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201621486542.5U CN206529484U (en) | 2016-12-31 | 2016-12-31 | Cell culture operations integral system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201621486542.5U CN206529484U (en) | 2016-12-31 | 2016-12-31 | Cell culture operations integral system |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN206529484U true CN206529484U (en) | 2017-09-29 |
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ID=59917562
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201621486542.5U Active CN206529484U (en) | 2016-12-31 | 2016-12-31 | Cell culture operations integral system |
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| Country | Link |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106701574A (en) * | 2016-12-31 | 2017-05-24 | 宁波华仪宁创智能科技有限公司 | Cell culture operation integrated system and working method thereof |
-
2016
- 2016-12-31 CN CN201621486542.5U patent/CN206529484U/en active Active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106701574A (en) * | 2016-12-31 | 2017-05-24 | 宁波华仪宁创智能科技有限公司 | Cell culture operation integrated system and working method thereof |
| WO2018121728A1 (en) * | 2016-12-31 | 2018-07-05 | 宁波大学 | Cell culture and operation integrated system and working method |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20201211 Address after: Area a, 4th floor, no.483, Xingnan Avenue, Nancun Town, Panyu District, Guangzhou City, Guangdong Province Patentee after: Guangzhou aibeitai Biotechnology Co.,Ltd. Patentee after: CHINA INNOVATION INSTRUMENT Co.,Ltd. Address before: Room 304, D Building, Kexin Building, 655 Xueshi Road, Yinzhou District, Ningbo City, Zhejiang Province, 315000 Patentee before: CHINA INNOVATION INSTRUMENT Co.,Ltd. |
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| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20220309 Address after: 510535 floor 1, building C2, No. 11, Kaiyuan Avenue, Huangpu District, Guangzhou, Guangdong Patentee after: GUANGZHOU HUAYUEHANG MEDICAL TECHNOLOGY Co.,Ltd. Address before: Area a, 4th floor, no.483, Xingnan Avenue, Nancun Town, Panyu District, Guangzhou City, Guangdong Province Patentee before: Guangzhou aibeitai Biotechnology Co.,Ltd. Patentee before: Ningbo Huayi ningchuang Intelligent Technology Co., Ltd |