CN206337281U - Cell culture incubator - Google Patents

Cell culture incubator Download PDF

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Publication number
CN206337281U
CN206337281U CN201621486693.0U CN201621486693U CN206337281U CN 206337281 U CN206337281 U CN 206337281U CN 201621486693 U CN201621486693 U CN 201621486693U CN 206337281 U CN206337281 U CN 206337281U
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China
Prior art keywords
cell culture
regulation device
gas
culture incubator
housing
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CN201621486693.0U
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Chinese (zh)
Inventor
闻路红
毕磊
王蓓蕾
史振志
李文
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Guangzhou Aibeitai Biotechnology Co ltd
Original Assignee
Ningbo Huayi Ningchuang Intelligent Science & Technology Co Ltd
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Priority to CN201621486693.0U priority Critical patent/CN206337281U/en
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Abstract

The utility model provides a kind of cell culture incubator, and the cell culture incubator includes housing;Supply unit, the supply unit is used to the gas in the housing being transported to regulation device;Regulation device, the regulation device is respectively at the storage of object gas, release conditions according to the difference of running parameter, and the output end of the regulation device connects the enclosure interior;The content of object gas in the housing measured is sent to processor by sensor, the sensor;Processor, the processor controls the working condition of the regulation device according to the content received.The utility model has the advantages that gas consumption is small.

Description

Cell culture incubator
Technical field
The utility model is related to cell culture, more particularly to cell culture incubator.
Background technology
The growing environment good to ensure cell, the culture region of cell or operating area need to keep certain gas Concentration (carbon dioxide or carbon dioxide and oxygen).Current gas control mode mainly using the gas for rising concentration and drops dense The gas of degree controls the concentration of internal gas by pid algorithm.
But such technology is primarily present following deficiency:Due to during liter concentration or drop concentration, in order in keeping The stabilization of portion's pressure, the injection meeting of gas causes the waste of injection gas along with the discharge of gas;Reduce the effect of control Rate.
Utility model content
To solve the deficiency in above-mentioned prior art, the utility model provides that a kind of gas consumption is small, gas The high cell culture incubator of concentration control efficiency.
The purpose of this utility model is achieved through the following technical solutions:
A kind of cell culture incubator, the cell culture incubator includes housing;The cell culture incubator further comprises:
Supply unit, the supply unit is used to the gas in the housing being transported to regulation device;
Regulation device, the regulation device is respectively at the storage of object gas, release according to the difference of running parameter State, the output end of the regulation device connects the enclosure interior;
The content of object gas in the housing measured is sent to processor by sensor, the sensor;
Processor, the processor controls the working condition of the regulation device according to the content received.
Prior art is compared, the utility model have the advantage that for:
1. reduce the loss of gas;
2. accelerate the efficiency of gas control;
3. the hot gas set protection interlayer of internal layer periphery, the temperature in the gas inside internal layer, interlayer is heated by air circulation Degree is higher than inside internal layer, effectively prevents that condensed water from occurring in internal layer inwall, reduces contaminated risk;
4. cell culture operations are integrated, the culture amount of cell is effectively increased.
Brief description of the drawings
Referring to the drawings, disclosure of the present utility model will be easier to understand.Skilled addressee readily understands that It is:These accompanying drawings are used only for illustrating the technical solution of the utility model, and are not intended to protection of the present utility model Scope is construed as limiting.In figure:
Fig. 1 is the structure diagram of the cell culture incubator according to the utility model embodiment 1;
Fig. 2 is the structure diagram of the cell culture incubator according to the utility model embodiment 3.
Embodiment
Fig. 1-2 and following description describe optional embodiment of the present utility model how to instruct those skilled in the art Implement and reproduce the utility model.In order to instruct technical solutions of the utility model, simplify or eliminate some conventional aspects.This Art personnel should be appreciated that modification or replacement from these embodiments will be in the range of the utility model.This area Technical staff should be appreciated that following characteristics can combine to form multiple modifications of the present utility model in a variety of ways.Thus, originally Utility model is not limited to following optional embodiments, and is only limited by claim and their equivalent.
Embodiment 1:
Fig. 1 schematically illustrates the structure diagram of the cell culture incubator of the utility model embodiment, as shown in figure 1, institute Stating cell culture incubator includes:
Housing, the housing has gas access, and the double-decker constituted for internal layer, outer layer;The upper wall of the internal layer There is through hole with lower wall;
Supply unit, such as blower fan, the supply unit are used to the gas in the housing being transported to regulation device, specifically It is arranged on the downside of the through hole of the upper wall of the internal layer;
Regulation device, the regulation device is respectively at the storage of object gas, release according to the difference of running parameter State, the output end of the regulation device connects the enclosure interior;The regulation device is 2, is oxygen molecule sieve, dioxy Change carbon molecular sieve, adsorption and desorption are carried out to gas molecule using pressure swing adsorption (PSA), so as to store, discharge target Gas;Regulation and control are arranged in the interlayer on the top of the double-decker;
Filter, the filter is arranged on the bottom of the supply unit, the projection of the filter in the horizontal plane The figure surrounded with the inwall of the internal layer on the horizontal plane is overlapped;
Oxygen in the housing measured, the content of carbon dioxide are sent to processor by sensor, the sensor;
Processor, the processor controls the working condition of the regulation device according to the content received:If less than mesh Scale value, makes regulation device be in release conditions by control;If higher than desired value, making regulation device be in storage shape by control State.
The control method of the cell culture incubator of the utility model embodiment, namely above-mentioned cell culture incubator method of work, The control method of the cell culture incubator comprises the following steps:
(A1) content of the object gas such as oxygen, carbon dioxide in gas sensor detection cell culture incubator internal layer, and It is sent to processor;
(A2) processor goes to control the working condition of regulation device according to the content received:
If desired for the content of reduction object gas, into step (A3);
If desired for the content of rise object gas, into step (A4);
As that need not adjust, into step (A5);
(A3) parameter of the regulation device is controlled, regulation device is in object gas storing state;In supply unit In the presence of, gas enters in interlayer from the lower wall of internal layer, is flowed up to along the interlayer between the wall of side in the interlayer between upper wall, Object gas in gas is adjusted device storage, finally enters from the upper wall of internal layer inside internal layer;Into step (A1);
(A4) parameter of the regulation device is controlled, object gas release conditions are in using regulation device;It is single in conveying In the presence of member, gas enters in interlayer from the lower wall of internal layer, the interlayer flowed up to along the interlayer between the wall of side between upper wall Interior, the object gas of regulation device storage is discharged into gas, is finally entered from the upper wall of internal layer inside internal layer;Into step (A1);
(A5) terminate;
In above process, if by circulating several times, the target gas content in internal layer still can not reach target Value, then need to inject foreign gas into the housing by the gas access on housing:As target gas content is all the time in housing Less than desired value, then inject target gas content and be higher than the gas of desired value, so as to reduce in housing object gas in gas Content;Target gas content is consistently higher than desired value in such as housing, then injects the gas that target gas content is less than desired value, from And reduce the content of object gas in gas in housing.
Embodiment 2:
The cell culture incubator of the utility model embodiment, as different from Example 1:
1. regulation device is arranged on the outside of the housing, input and output end are respectively communicated with the double-decker of housing Interlayer between the wall of side;
2. being additionally provided with supply unit, the gas of interlayer is transported to the regulation device.
Embodiment 3:
Fig. 2 schematically illustrates the structure diagram of the cell culture incubator of the utility model embodiment, as shown in Fig. 2 institute Stating cell culture incubator includes:
Housing, the housing has gas access, gas vent and humidification port, and the double-deck knot constituted for internal layer, outer layer Structure;The upper wall and lower wall of the internal layer have through hole;The front side of housing has operation gloves;
Conveyor module, such as blower fan, the conveyor module are arranged on the through hole of the upper wall of the internal layer or the downside of through hole, For the gas in the internal layer to be transported into regulation device so that gas is in internal layer, interlayer internal circulation flow;
Heating module, the flake heater, the heating module is arranged in the interlayer, such as the inwall of outer layer, side Portion's interlayer, top interlayer, bottom interlayer have heating module, wherein the heating module in the interlayer of front side is transparent, are easy to see Internal layer is examined, while improving heating uniformity;
Filter, the filter is arranged on the bottom of the conveyor module, the projection of the filter in the horizontal plane The figure surrounded with the inwall of the internal layer on the horizontal plane is overlapped;
Regulation device, the regulation device is respectively at the storage of object gas, release according to the difference of running parameter State, the regulation device is arranged in the top interlayer;The regulation device is 2, is oxygen molecule sieve, carbon dioxide Molecular sieve, carries out adsorption and desorption, so as to store, discharge object gas using pressure swing adsorption (PSA) to gas molecule;
Oxygen in the internal layer measured, the content of carbon dioxide are sent to processor by sensor, the sensor;
Processor, the processor controls the working condition of the regulation device according to the content received:If less than mesh Scale value, makes regulation device be in release conditions by control;If higher than desired value, making regulation device be in storage shape by control State.
The control method of the cell culture incubator of the utility model embodiment, the control method of the cell culture incubator include with Lower step:
(A1) the target gas such as oxygen, carbon dioxide in gas sensor detection cell culture operations integral system internal layer The content of body, and it is sent to processor;
(A2) processor goes to control the working condition of regulation device according to the content received:
If desired for the content of reduction object gas, into step (A3);
If desired for the content of rise object gas, into step (A4);
As that need not adjust, into step (A5);
(A3) parameter of the regulation device is controlled, regulation device is in object gas storing state;In conveyor module In the presence of, gas enters in interlayer from the lower wall of internal layer, is flowed up to along the interlayer between the wall of side in the interlayer between upper wall, Object gas in gas is adjusted device storage, finally enters from the upper wall of internal layer inside internal layer;Into step (A1);
(A4) parameter of the regulation device is controlled, object gas release conditions are in using regulation device;In conveying mould In the presence of block, gas enters in interlayer from the lower wall of internal layer, the interlayer flowed up to along the interlayer between the wall of side between upper wall Interior, the object gas of regulation device storage is discharged into gas, is finally entered from the upper wall of internal layer inside internal layer;Into step (A1);
(A5) terminate;
In above process, if by circulating several times, the target gas content in internal layer still can not reach target Value, then need to inject foreign gas into the housing by the gas access on housing:As target gas content is all the time in housing Less than desired value, then inject target gas content and be higher than the gas of desired value, so as to reduce in housing object gas in gas Content;Target gas content is consistently higher than desired value in such as housing, then injects the gas that target gas content is less than desired value, from And reduce the content of object gas in gas in housing;
In the above-mentioned course of work, the gas in heating module heating interlayer so that the temperature in interlayer is higher than in internal layer Temperature, the inwall of the internal layer do not have condensed water.

Claims (7)

1. a kind of cell culture incubator, the cell culture incubator includes housing;It is characterized in that:The cell culture incubator is further wrapped Include:
Supply unit, the supply unit is used to the gas in the housing being transported to regulation device;
Regulation device, the regulation device is respectively at the storage of object gas, release conditions according to the difference of running parameter, The output end of the regulation device connects the enclosure interior;
The content of object gas in the housing measured is sent to processor by sensor, the sensor;
Processor, the processor controls the working condition of the regulation device according to the content received.
2. cell culture incubator according to claim 1, it is characterised in that:The housing has gas access.
3. cell culture incubator according to claim 1, it is characterised in that:The housing is internal layer, the bilayer of outer layer composition Structure;The upper wall and lower wall of the internal layer have through hole.
4. cell culture incubator according to claim 3, it is characterised in that:The regulation device is arranged on the folder of double-decker In layer, supply unit is arranged on the downside of the through hole of the upper wall of the internal layer.
5. cell culture incubator according to claim 4, it is characterised in that:The cell culture incubator further comprises:
Filter, the figure that the projection of the filter in the horizontal plane is surrounded with the inwall of the internal layer on the horizontal plane Overlap.
6. cell culture incubator according to claim 1, it is characterised in that:The regulation device is arranged on the outer of the housing Portion.
7. cell culture incubator according to claim 1, it is characterised in that:The object gas is oxygen, carbon dioxide, institute Regulation device is stated for molecular sieve.
CN201621486693.0U 2016-12-31 2016-12-31 Cell culture incubator Active CN206337281U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201621486693.0U CN206337281U (en) 2016-12-31 2016-12-31 Cell culture incubator

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201621486693.0U CN206337281U (en) 2016-12-31 2016-12-31 Cell culture incubator

Publications (1)

Publication Number Publication Date
CN206337281U true CN206337281U (en) 2017-07-18

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Country Status (1)

Country Link
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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106635792A (en) * 2016-12-31 2017-05-10 宁波华仪宁创智能科技有限公司 Cell culture box and control method
WO2018121728A1 (en) * 2016-12-31 2018-07-05 宁波大学 Cell culture and operation integrated system and working method
CN108467836A (en) * 2018-05-07 2018-08-31 宁波华仪宁创智能科技有限公司 Fertilized eggs culture apparatus and its working method

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106635792A (en) * 2016-12-31 2017-05-10 宁波华仪宁创智能科技有限公司 Cell culture box and control method
WO2018121728A1 (en) * 2016-12-31 2018-07-05 宁波大学 Cell culture and operation integrated system and working method
CN108467836A (en) * 2018-05-07 2018-08-31 宁波华仪宁创智能科技有限公司 Fertilized eggs culture apparatus and its working method

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Effective date of registration: 20201221

Address after: Area a, 4th floor, no.483, Xingnan Avenue, Nancun Town, Panyu District, Guangzhou City, Guangdong Province

Patentee after: Guangzhou aibeitai Biotechnology Co.,Ltd.

Patentee after: CHINA INNOVATION INSTRUMENT Co.,Ltd.

Address before: Room 304, D Building, Kexin Building, 655 Xueshi Road, Yinzhou District, Ningbo City, Zhejiang Province, 315000

Patentee before: CHINA INNOVATION INSTRUMENT Co.,Ltd.

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Effective date of registration: 20220310

Address after: 510535 floor 1, building C2, No. 11, Kaiyuan Avenue, Huangpu District, Guangzhou, Guangdong

Patentee after: GUANGZHOU HUAYUEHANG MEDICAL TECHNOLOGY Co.,Ltd.

Address before: Area a, 4th floor, no.483, Xingnan Avenue, Nancun Town, Panyu District, Guangzhou City, Guangdong Province

Patentee before: Guangzhou aibeitai Biotechnology Co.,Ltd.

Patentee before: CHINA INNOVATION INSTRUMENT Co.,Ltd.

TR01 Transfer of patent right
TR01 Transfer of patent right

Effective date of registration: 20220704

Address after: Area a, 4th floor, no.483, Xingnan Avenue, Nancun Town, Panyu District, Guangzhou City, Guangdong Province

Patentee after: Guangzhou aibeitai Biotechnology Co.,Ltd.

Address before: 510535 floor 1, building C2, No. 11, Kaiyuan Avenue, Huangpu District, Guangzhou, Guangdong

Patentee before: GUANGZHOU HUAYUEHANG MEDICAL TECHNOLOGY Co.,Ltd.