CN206526023U - A kind of eyeground blood flow blood oxygen saturation detection means based on face matrix LED - Google Patents
A kind of eyeground blood flow blood oxygen saturation detection means based on face matrix LED Download PDFInfo
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- CN206526023U CN206526023U CN201621276300.3U CN201621276300U CN206526023U CN 206526023 U CN206526023 U CN 206526023U CN 201621276300 U CN201621276300 U CN 201621276300U CN 206526023 U CN206526023 U CN 206526023U
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- matrix led
- face matrix
- oxygen saturation
- blood oxygen
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Abstract
The utility model is related to a kind of eyeground blood flow blood oxygen saturation detection means based on face matrix LED, and the device includes synchronous trigger source, data handling system, face matrix LED light source, spectroscope, connects mesh object lens, image-forming objective lens, CCD color cameras and the Baeyer filter on CCD color cameras；Face matrix LED light source is alternately arranged by two kinds of wavelength LEDs and constituted；Synchronous trigger source is used to send synchronizing signal to face matrix LED light source and CCD color cameras, when adjacent sync signal is sent, the light that face matrix LED light source sends two kinds of wavelength respectively reaches spectroscope, dichroic mirror light is to connecing mesh object lens and reach the eyeground of positive docking mesh object lens, light is again introduced into after fundus reflex to be connect mesh object lens and enters image-forming objective lens through spectroscope, and CCD color cameras gather the speckle image by the light formation of two kinds of wavelength of image-forming objective lens and transmit it to data handling system and handled to obtain blood oxygen saturation respectively.The utility model is to human body without any damage, and the precision of the blood oxygen saturation of detection is high.
Description
Technical field
The utility model is related to technical field of medical instruments, more particularly, to a kind of eyeground blood flow based on face matrix LED
Blood oxygen saturation detection means.
Background technology
Blood oxygen saturation refer to the percentage that hemoglobin is combined by oxygen, i.e. hemoglobin oxygen content and oxygen capacity hundred
Divide ratio, it is an important parameter of respiratory and circulatory function, reflect the blood oxygen balance of human body.Some diseases can be to the device of human body
Official or tissue cause anoxic, cause histiocytic metabolic disorder, homeostasis is unbalance, and serious can also threaten the life of people
Life, and blood oxygen saturation monitoring is carried out to patient and will be helpful to solve this problem.Eye ground is the one of systemic microcirculation
Part, it needs the supply of oxygen to maintain its normal metabolism, and its reflection changed for blood oxygen is more sensitive, just
It is monitored in blood oxygen saturation.
Based on the device of existing detection blood oxygen saturation, measurement blood oxygen saturation, which is mainly, uses electrochemical process, this method
Advanced row human blood collection (extracting arterial blood) recycles blood gas analyzer to carry out electrochemical analysis to blood, directly measures artery oxygen
Press (PaO2), and calculate arterial oxygen saturation (SpO2)；It is relatively number but this method needs arteriopuncture or intubation
It is tired, and can not continuously be monitored, it is a kind of oximetry for having a damage, and for easily causing the position of damage just
Electrochemical process difficult to use is measured.There is a kind of monitoring method of detecting sphygmus and blood oxygen saturation in addition, this method is easily by light
Interference, such as interference of sunlight, operating room lights, if these light enter detector in measurement, influences the transmission obtained
The intensity size of light, so that the accuracy of blood oxygen saturation parameter is finally influenceed, and the only numerical value of pulse oxymeter
During more than 83%, 3% error can be only achieved.
So, there is detection essence when carrying out the measurement of blood oxygen saturation using the device of existing detection blood oxygen saturation
The problem of degree is not high is, it is necessary to improve.
Utility model content
The purpose of this utility model is to overcome the deficiencies in the prior art that there is provided a kind of eyeground blood flow based on face matrix LED
Blood oxygen saturation detection means, the device can non-contactly measure the blood oxygen saturation of human body eyeground blood flow, to human body without appoint
What is damaged, and the signal noise ratio (snr) of image shot is high, spatial resolution is high, and the precision of the blood oxygen saturation of detection is high.
In order to solve the above technical problems, the technical solution adopted in the utility model is：
A kind of eyeground blood flow blood oxygen saturation detection means based on face matrix LED is provided, including at synchronous trigger source, data
Reason system, face matrix LED light source, spectroscope, connect mesh object lens, image-forming objective lens, CCD color cameras and on CCD color cameras
Baeyer filter；Face matrix LED light source is alternately composed in series by two kinds of wavelength LEDs；Synchronous trigger source is used for face matrix LED light source
And CCD color cameras send synchronizing signal, when synchronizing signal is sent, the light that face matrix LED light source is simultaneously emitted by two kinds of wavelength is reached
Spectroscope, dichroic mirror light is to connecing mesh object lens and reaching the positive eyeground for docking mesh object lens, and light is again introduced into after fundus reflex
Connect mesh object lens and enter image-forming objective lens, the light shape for two kinds of wavelength that the collection of CCD color cameras passes through image-forming objective lens through spectroscope
Into speckle image and transmit it to data handling system and handled to obtain blood oxygen saturation.Face matrix LED light source, light splitting
Mirror and connect mesh object lens composition fundus illumination light path system；CCD color cameras, Baeyer filter, image-forming objective lens, spectroscope and connect mesh thing
Microscope group is into fundus imaging light path system；The effect for connecing mesh object lens and image-forming objective lens is control imaging focal length, to shoot high spatial
The speckle image of resolution ratio.
In such scheme, the face matrix LED light source that is alternately composed in series by two kinds of wavelength LEDs by setting and with synchronous tactile
Rise and send synchronizing signal to face matrix LED light source and CCD color cameras so that when synchronizing signal is sent, face matrix LED light source is simultaneously
The light of two kinds of wavelength is sent, CCD color cameras gather the speckle image of the light formation of two kinds of wavelength and transmitted it at data
Reason system is handled to obtain blood oxygen saturation.A kind of eyeground blood flow blood oxygen saturation based on face matrix LED of the utility model
Detection means, can non-contactly measure the blood oxygen saturation of human body eyeground blood flow, to human body without any damage, pass through collection two
The influence that eye position changes and oxygen content of blood change is brought, and shooting can effectively be suppressed by planting the speckle image of the light formation of wavelength
Signal noise ratio (snr) of image is high, spatial resolution is high, the precision of the blood oxygen saturation of detection is high.
Preferably, the data handling system is computer.
Preferably, matrix LED light source in face is λ by wavelength1=532nm and λ2=632nm LED is alternately in series.It is blood red
Albumen is larger to the absorption coefficient difference of the light of both wavelength, and the error produced during calculating is small, is conducive to improving the blood detected
The precision of oxygen saturation.
Compared with prior art, the beneficial effects of the utility model are：
A kind of eyeground blood flow blood oxygen saturation detection means based on face matrix LED of the utility model, by setting by two kinds
Wavelength LED replaces the face matrix LED light source being composed in series and sent out with synchronous trigger source to face matrix LED light source and CCD color cameras
Go out synchronizing signal so that when synchronizing signal is sent, face matrix LED light source is simultaneously emitted by the light of two kinds of wavelength, the collection of CCD color cameras
The speckle image of the light formation of two kinds of wavelength simultaneously transmits it to data handling system and is handled to obtain blood oxygen saturation, this
Device can non-contactly measure the blood oxygen saturation of human body eyeground blood flow, to human body without any damage, by gathering two kinds of ripples
The speckle image of long light formation can effectively suppress the influence that eye position changes and oxygen content of blood change is brought, and the figure shot
As signal to noise ratio height, spatial resolution height, the precision of the blood oxygen saturation of detection is high；By by face matrix LED light source by wavelength be λ1
=532nm and λ2=632nm LED is alternately in series, due to absorption coefficient of the hemoglobin to the light of both wavelength
Difference is larger so that the error produced during calculating is small, is conducive to improving the precision of the blood oxygen saturation detected.
Brief description of the drawings
Fig. 1 is a kind of schematic diagram of the eyeground blood flow blood oxygen saturation detection means based on face matrix LED of the present embodiment, wherein
Arrow represents that light is moved towards.
Fig. 2 is the arrangement schematic diagram of three color chips of CCD color cameras, wherein, only illustrate red and green arrangement
Mode.
Fig. 3 is response coefficient curve map of the green red blue response chip of CCD color cameras to different wavelengths of light.
Fig. 4 is the arrangement schematic diagram of face matrix LED light source in the present embodiment.
Embodiment
The utility model is further described with reference to embodiment.Wherein, being given for example only property of accompanying drawing
Illustrate, expression is only schematic diagram, rather than pictorial diagram, it is impossible to be interpreted as the limitation to this patent；In order to which this reality is better described
With new embodiment, some parts of accompanying drawing have omission, zoomed in or out, and do not represent the size of actual product；To ability
For field technique personnel, some known features and its explanation may be omitted and will be understood by accompanying drawing.
The same or analogous part of same or analogous label correspondence in the accompanying drawing of the utility model embodiment；In this practicality
In new description, it is to be understood that if the orientation or position relationship that have the instructions such as term " on ", " under ", "left", "right" are
Based on orientation shown in the drawings or position relationship, it is for only for ease of description the utility model and simplifies description, rather than indicate
Or imply that signified device or element must have specific orientation, to be retouched in specific azimuth configuration and operation, therefore accompanying drawing
Term the being given for example only property explanation of position relationship is stated, it is impossible to be interpreted as the limitation to this patent, for the common skill of this area
For art personnel, the concrete meaning of above-mentioned term can be understood as the case may be.
Embodiment
A kind of schematic diagram of the eyeground blood flow blood oxygen saturation detection means based on face matrix LED of the present embodiment as shown in figure 1,
Including synchronous trigger source 8, data handling system 9, face matrix LED light source 7, spectroscope 4, to meet mesh object lens 5, image-forming objective lens 3, CCD color
Form and aspect machine 1 and the Baeyer filter 2 on CCD color cameras 1；Face matrix LED light source 7 is alternately connected by two kinds of wavelength LEDs
Composition；Synchronous trigger source 8 is used to send synchronizing signal to face matrix LED light source 7 and CCD color cameras 1, when synchronizing signal is sent,
The light that face matrix LED light source 7 is simultaneously emitted by two kinds of wavelength reaches spectroscope 4, and the reflected light of spectroscope 4 is to connecing mesh object lens 5 and arrival just
The eyeground of mesh object lens 5 is docked, light is again introduced into after fundus reflex to be connect mesh object lens 5 and enter image-forming objective lens 3 through spectroscope 4,
The speckle image of the light formation for two kinds of wavelength that the collection of CCD color cameras 1 passes through image-forming objective lens 3 simultaneously transmits it to data processing
System 9 is handled to obtain blood oxygen saturation.
In the present embodiment, face matrix LED light source 7, spectroscope 4 and the composition of mesh object lens 5 fundus illumination light path system 10 is connect；CCD
Color camera 1, Baeyer filter 2, image-forming objective lens 3, spectroscope 4 and connect the composition of mesh object lens 5 fundus imaging light path system 11；CCD is color
The arrangement schematic diagram of three color chips of form and aspect machine is as shown in Fig. 2 Baeyer filter 2 is arranged on CCD color cameras 1, light warp
Cross after Baeyer filter 2, redgreenblue, wherein green glow optimal response ripple are divided into by the CCD chip on CCD color cameras 1
A length of 532nm, and feux rouges optimal response wavelength is 632nm, the green red blue response chip (pixel) of CCD color cameras 1 is to difference
The response coefficient curve map of wavelength light is as shown in Figure 3；The effect for connecing mesh object lens 5 and image-forming objective lens 3 is control imaging focal length, to clap
Take out the speckle image of high spatial resolution.
When detecting the blood oxygen saturation of human body eyeground blood flow using the device, the just docking mesh object lens 5 of eyes 6, synchronous triggering
Source 8 sends synchronizing signal to face matrix LED light source 7 and CCD color cameras 1 so that face matrix LED light source 7 is simultaneously emitted by two kinds of wavelength
Light reach spectroscope 4, the reflected light of spectroscope 4 is to connecing mesh object lens 5 and reach eyes 6, and light is again introduced into after being reflected from eyes 6 and connect
Mesh object lens 5 simultaneously enter image-forming objective lens 3, the light for two kinds of wavelength that the collection of CCD color cameras 1 passes through image-forming objective lens 3 through spectroscope 4
The speckle image of formation, is λ by corresponding wavelength according to the distribution of the pixel of CCD color cameras 11And λ2Light formation speckle
Image is separated, and the wavelength that 9 pairs of data handling system is separated is λ1And λ2Light formation speckle image located respectively
Reason, to obtain blood oxygen saturation.A kind of eyeground blood flow blood oxygen saturation detection means based on face matrix LED of the utility model, energy
The blood oxygen saturation of human body eyeground blood flow is non-contactly measured, to human body without any damage, by the light for gathering two kinds of wavelength
The speckle image of formation can effectively suppress the influence that eye position changes and oxygen content of blood change is brought, and the image noise shot
Higher than high, spatial resolution, the precision of the blood oxygen saturation of detection is high.
In the present embodiment, the data handling system 9 is computer.
Wherein, face matrix LED light source 7 is λ by wavelength1=532nm and λ2=632nm LED is alternately in series, such as Fig. 4
It is shown.Hemoglobin is larger to the absorption coefficient difference of the light of both wavelength, and the error produced during calculating is small, is conducive to improving
The precision of the blood oxygen saturation of detection.
When being detected using the above-mentioned eyeground blood flow blood oxygen saturation detection means based on face matrix LED, including following step
Suddenly：
S1., picking rate and the time for exposure of CCD color cameras 1 are set so that erythrocyte turnover pixel cell into
During as scope, the change in concentration of local causes the change of dynamical speckle interferometry intensity；By the just docking mesh object lens 5 of eyes 6；
S2. synchronous trigger source 8 is with frequency f0The subsynchronous signals of n, n times are sent to face matrix LED light source 7 and CCD color cameras 1
Triggering face matrix LED light source 7 is simultaneously emitted by wavelength for λ1And λ2Light reach spectroscope 4, the reflected light of spectroscope 4 is to connecing mesh object lens 5 simultaneously
Eyeground is reached, light is again introduced into after fundus reflex to be connect mesh object lens 5 and enter image-forming objective lens 3 through spectroscope 4, meanwhile, n times is tactile
It is λ to send out CCD color cameras 1 and gather by the wavelength of image-forming objective lens 31And λ2Light formation speckle image, wherein, λ1=
532nm, λ2=632nm；
S3. the wavelength by image-forming objective lens 3 CCD color cameras 1 gathered is λ1And λ2Light formation speckle image pass
Transport to data handling system 9 to be handled to obtain the blood oxygen saturation of eyeground blood flow, comprise the following steps：
S31. it is λ by corresponding wavelength according to the distribution of the pixel of CCD color cameras 11And λ2Light formation speckle pattern
As separating；
S32. it is λ to the wavelength isolated1And λ2The speckle image that is formed respectively of light in each pixel carry out it is quick
Fourier transformation, it is strong that the temporal speckle strength signal that CCD color cameras 1 are received is changed into frequency domain speckle along time series
Spend signal；
S33. processing is filtered to frequency domain speckle strength signal, the low frequency signal and reflection blood of background information will be reflected
The high-frequency signal of liquid flowing is separated, wherein, low frequency signal is static speckles signal, and high-frequency signal is dynamic speckle signal；
S34. inverse Fourier transform is carried out respectively to the low frequency signal and high-frequency signal separated, to obtain static speckles
Signal intensityWithDynamic speckle signal intensityWith
S35. the light intensity through biological tissue can be expressed as：
Wherein, I is transmitted light intensity, I0For incident intensity, ε0For the absorption coefficient of light of background information, C0For background information
Light absorbs material concentration, L is optical path length；
According to Beer-Lambert laws, (1) formula can be expressed as (2) formula：
Wherein,For the absorption coefficient of light of oxyhemoglobin,For the concentration of oxyhemoglobin, εHb
For the absorption coefficient of light of deoxyhemoglobin, cHbFor the concentration of deoxyhemoglobin；
And εHbIt is λ in wavelength1And λ2When the absorption coefficient of light be constant；
S36. (2) formula is calculated, obtains the content of oxyhemoglobinWith the content of deoxyhemoglobin
CHb；
S37. the blood oxygen saturation of eyeground blood flow is calculated according to blood oxygen saturation formula (4)；
Wherein, SO2The as blood oxygen saturation of eyeground blood flow.
Obviously, above-described embodiment of the present utility model is only intended to clearly illustrate the utility model example, and
It is not the restriction to embodiment of the present utility model.For those of ordinary skill in the field, in described above
On the basis of can also make other changes in different forms.There is no need and unable to give all embodiments
It is exhaustive.All any modifications, equivalent substitutions and improvements made within spirit of the present utility model and principle etc., should be included in
Within the utility model scope of the claims.
Claims (3)
1. a kind of eyeground blood flow blood oxygen saturation detection means based on face matrix LED, it is characterised in that including synchronous trigger source
(8), data handling system (9), face matrix LED light source (7), spectroscope (4), to meet mesh object lens (5), image-forming objective lens (3), CCD colored
Camera (1) and the Baeyer filter (2) on CCD color cameras (1)；Face matrix LED light source (7) is handed over by two kinds of wavelength LEDs
For being composed in series；Synchronous trigger source (8) is used to send synchronizing signal to face matrix LED light source (7) and CCD color cameras (1), synchronous
When signal is sent, the light that face matrix LED light source (7) is simultaneously emitted by two kinds of wavelength reaches spectroscope (4), and spectroscope (4) reflected light is arrived
Connect mesh object lens (5) and reach the eyeground of positive docking mesh object lens (5), light is again introduced into after fundus reflex connects mesh object lens (5) and saturating
Cross spectroscope (4) and enter image-forming objective lens (3), the light shape for two kinds of wavelength that CCD color cameras (1) collection passes through image-forming objective lens (3)
Into speckle image and transmit it to data handling system (9) and handled to obtain blood oxygen saturation.
2. a kind of eyeground blood flow blood oxygen saturation detection means based on face matrix LED according to claim 1, its feature exists
In the data handling system (9) is computer.
3. a kind of eyeground blood flow blood oxygen saturation detection dress based on face matrix LED according to any one of claim 1 to 2
Put, it is characterised in that face matrix LED light source (7) is λ by wavelength1=532nm and λ2=632nm LED is alternately in series.
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| CN201621276300.3U CN206526023U (en) | 2016-11-25 | 2016-11-25 | A kind of eyeground blood flow blood oxygen saturation detection means based on face matrix LED |
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| CN201621276300.3U CN206526023U (en) | 2016-11-25 | 2016-11-25 | A kind of eyeground blood flow blood oxygen saturation detection means based on face matrix LED |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106618476A (en) * | 2016-11-25 | 2017-05-10 | 佛山科学技术学院 | Device and method for detecting eye-ground-blood-flow blood-oxygen saturation degree based on area array LED |
| CN107788951A (en) * | 2017-11-23 | 2018-03-13 | 加动健康科技（芜湖）有限公司 | Spectral emissions device for health detection |
| CN108113682A (en) * | 2017-10-31 | 2018-06-05 | 北京心灵方舟科技发展有限公司 | Measure device, the method and apparatus of oxygen-containing hemoglobin and deoxyhemoglobin |
-
2016
- 2016-11-25 CN CN201621276300.3U patent/CN206526023U/en not_active Expired - Fee Related
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106618476A (en) * | 2016-11-25 | 2017-05-10 | 佛山科学技术学院 | Device and method for detecting eye-ground-blood-flow blood-oxygen saturation degree based on area array LED |
| CN106618476B (en) * | 2016-11-25 | 2018-05-11 | 佛山科学技术学院 | A kind of eyeground blood flow method for detecting blood oxygen saturation based on face matrix LED |
| CN108113682A (en) * | 2017-10-31 | 2018-06-05 | 北京心灵方舟科技发展有限公司 | Measure device, the method and apparatus of oxygen-containing hemoglobin and deoxyhemoglobin |
| CN107788951A (en) * | 2017-11-23 | 2018-03-13 | 加动健康科技（芜湖）有限公司 | Spectral emissions device for health detection |
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